Claudio Grosman

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
AChR
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"Claudio Grosman"
Mean distance: 15.65 (cluster 32)
 
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Shyam M. Saladi research assistant 2011-2014 UIUC (Chemistry Tree)
Tyler Harpole grad student UIUC
Yamini Purohit grad student 2006 UIUC
David J. Papke grad student 2013 UIUC
Giovanni Gonzalez-Gutierrez post-doc
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Publications

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Kumar P, Cymes GD, Grosman C. (2021) Structure and function at the lipid-protein interface of a pentameric ligand-gated ion channel. Proceedings of the National Academy of Sciences of the United States of America. 118
Cymes GD, Grosman C. (2021) Signal transduction through Cys-loop receptors is mediated by the nonspecific bumping of closely apposed domains. Proceedings of the National Academy of Sciences of the United States of America. 118
Kumar P, Wang Y, Zhang Z, et al. (2020) Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayer. Proceedings of the National Academy of Sciences of the United States of America
Harpole TJ, Grosman C. (2019) A Crucial Role for Side-Chain Conformation in the Versatile Charge Selectivity of Cys-Loop Receptors. Biophysical Journal
Gonzalez-Gutierrez G, Wang Y, Cymes GD, et al. (2017) Chasing the open-state structure of pentameric ligand-gated ion channels. The Journal of General Physiology
Cymes GD, Grosman C. (2016) Identifying the elusive link between amino acid sequence and charge selectivity in pentameric ligand-gated ion channels. Proceedings of the National Academy of Sciences of the United States of America
Cymes GD, Grosman C. (2015) Engineered Ionizable Side Chains. Advances in Experimental Medicine and Biology. 869: 5-23
Gonzalez-Gutierrez G, Grosman C. (2015) The atypical cation-conduction and gating properties of ELIC underscore the marked functional versatility of the pentameric ligand-gated ion-channel fold. The Journal of General Physiology. 146: 15-36
Harpole TJ, Grosman C. (2014) Side-chain conformation at the selectivity filter shapes the permeation free-energy landscape of an ion channel. Proceedings of the National Academy of Sciences of the United States of America. 111: E3196-205
Papke D, Grosman C. (2014) The role of intracellular linkers in gating and desensitization of human pentameric ligand-gated ion channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 7238-52
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