David I. Hirsh

1971-1985 University of Colorado, Boulder, Boulder, CO, United States 
 1985- Columbia University, New York, NY 
nucleic acid structure and function and gene activity during early development of C. elegans
"David Ian Hirsh"


Mean distance: 14.46 (cluster 32)


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Fritz Albert Lipmann grad student 1968 Rockefeller (Chemistry Tree)
 (The hydroxamate reaction of aminoacyl-tRNA synthetases.)
Sydney Brenner post-doc 1968-1971 MRC-LMB


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Patrick O'Farrell grad student
James Priess grad student CU Boulder
Judith E. Kimble grad student 1978 CU Boulder (Chemistry Tree)
Craig Cameron Mello grad student 1982 CU Boulder
Vera M. Irikura grad student 2000 Columbia
Scott Emmons post-doc CU Boulder
Kenneth Kemphues post-doc CU Boulder (Cell Biology Tree)
Dan Stinchcomb post-doc CU Boulder
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Irikura VM, Lagraoui M, Hirsh D. (2002) The epistatic interrelationships of IL-1, IL-1 receptor antagonist, and the type I IL-1 receptor. Journal of Immunology (Baltimore, Md. : 1950). 169: 393-8
Zhang Y, Grant B, Hirsh D. (2001) RME-8, a conserved J-domain protein, is required for endocytosis in Caenorhabditis elegans. Molecular Biology of the Cell. 12: 2011-21
Lin SX, Grant B, Hirsh D, et al. (2001) Rme-1 regulates the distribution and function of the endocytic recycling compartment in mammalian cells. Nature Cell Biology. 3: 567-72
Josephs MD, Solorzano CC, Taylor M, et al. (2000) Modulation of the acute phase response by altered expression of the IL-1 type 1 receptor or IL-1ra. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 278: R824-30
Grant B, Hirsh D. (1999) Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte. Molecular Biology of the Cell. 10: 4311-26
Irikura VM, Hirsch E, Hirsh D. (1999) Effects of interleukin-1 receptor antagonist overexpression on infection by Listeria monocytogenes. Infection and Immunity. 67: 1901-9
Ma Y, Thornton S, Boivin GP, et al. (1998) Altered susceptibility to collagen-induced arthritis in transgenic mice with aberrant expression of interleukin-1 receptor antagonist. Arthritis and Rheumatism. 41: 1798-805
Hirsch E, Irikura VM, Paul SM, et al. (1996) Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 11008-13
Lee YH, Huang XY, Hirsh D, et al. (1992) Conservation of gene organization and trans-splicing in the glyceraldehyde-3-phosphate dehydrogenase-encoding genes of Caenorhabditis briggsae. Gene. 121: 227-35
Huang XY, Hirsh D. (1989) A second trans-spliced RNA leader sequence in the nematode Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 86: 8640-4
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