Horace H. Loh

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Opioid pharmacology
Website:
http://www.pharmacology.med.umn.edu/staffloh.html
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"Horace Loh"
Mean distance: 17.32 (cluster 32)
 
SNBCP
Cross-listing: Chemistry Tree

Children

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Wanling Yang grad student 2002 UMN
Guilin Wang grad student 2005 UMN
Qifang Wu grad student 2009 UMN
Hong-Yiou D. Lin grad student 2012 UMN
R. Adron Harris post-doc 1973-1976 UCSF
Yulong Chen research scientist

Collaborators

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Dezhi Liao collaborator UMN
BETA: Related publications

Publications

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Lin SY, Chang YC, Tien YW, et al. (2024) DBPR116, a Prodrug of BPRMU191, in Combination with Naltrexone as a Safer Opioid Analgesic Than Morphine via Peripheral Administration. Journal of Medicinal Chemistry. 67: 19777-19790
Huang YH, Lin SY, Ou LC, et al. (2024) Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia. Cell Chemical Biology
Hsu YT, Chen SR, Chang YC, et al. (2023) A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects. European Journal of Medicinal Chemistry. 258: 115608
Kuppusamy R, Hsu YT, Ke YY, et al. (2022) Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation. European Journal of Medicinal Chemistry. 243: 114728
Liang L, Chen J, Li Y, et al. (2020) Morphine and Naloxone Facilitate Neural Stem Cells Proliferation via a TET1-Dependent and Receptor-Independent Pathway. Cell Reports. 30: 3625-3631.e6
Chen J, Liang L, Li Y, et al. (2020) Naloxone regulates the differentiation of neural stem cells via a receptor-independent pathway. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Huang YH, Wu YW, Chuang JY, et al. (2020) Morphine produces potent antinociception, sedation, and hypothermia in humanized mice expressing human mu opioid receptor splice variants. Pain
Huang Y, Yeh S, Loh HH, et al. (2020) Pharmacological studies of morphine in a novel humanized mu opioid receptor mouse model The Faseb Journal. 34: 1-1
Chao PK, Chang HF, Chang WT, et al. (2019) BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine. Neuropharmacology. 107678
Yang PP, Yeh TK, Loh HH, et al. (2019) Delta-opioid receptor antagonist naltrindole reduces oxycodone addiction and constipation in mice. European Journal of Pharmacology
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