William Klein, PhD

Affiliations: 
Neurobiology and Physiology Northwestern University, Evanston, IL 
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"William Klein"
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Faisal Fecto research assistant 2006-2006 Northwestern
Syed Ather Enam grad student Northwestern
Whitney Pope grad student 1989-1994 Northwestern
Brett A. Chromy grad student 2001 Northwestern
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Publications

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Savioz A, Giannakopoulos P, Herrmann FR, et al. (2016) A Study of Aβ Oligomers in the Temporal Cortex and Cerebellum of Patients with Neuropathologically Confirmed Alzheimer's Disease Compared to Aged Controls. Neuro-Degenerative Diseases. 16: 398-406
Wilcox KC, Marunde MR, Das A, et al. (2015) Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers. Plos One. 10: e0125263
Baker-Nigh A, Vahedi S, Davis EG, et al. (2015) Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer's disease. Brain : a Journal of Neurology. 138: 1722-37
Clarke JR, Lyra E Silva NM, Figueiredo CP, et al. (2015) Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation. Embo Molecular Medicine. 7: 190-210
Viola KL, Klein WL. (2015) Amyloid β oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis. Acta Neuropathologica. 129: 183-206
Viola KL, Sbarboro J, Sureka R, et al. (2015) Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease. Nature Nanotechnology. 10: 91-8
Knight EM, Williams HN, Stevens AC, et al. (2015) Evidence that small molecule enhancement of β-hexosaminidase activity corrects the behavioral phenotype in Dutch APP(E693Q) mice through reduction of ganglioside-bound Aβ. Molecular Psychiatry. 20: 109-17
Sebollela A, Mustata GM, Luo K, et al. (2014) Elucidating molecular mass and shape of a neurotoxic Aβ oligomer. Acs Chemical Neuroscience. 5: 1238-45
Forny-Germano L, Lyra e Silva NM, Batista AF, et al. (2014) Alzheimer's disease-like pathology induced by amyloid-β oligomers in nonhuman primates. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 13629-43
Heffern MC, Velasco PT, Matosziuk LM, et al. (2014) Modulation of amyloid-β aggregation by histidine-coordinating Cobalt(III) Schiff base complexes. Chembiochem : a European Journal of Chemical Biology. 15: 1584-9
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