Tracy L. Young-Pearse, Ph.D.

Affiliations: 
Neurology Harvard University/Brigham and Women's 
Area:
Development, schizophrenia, Alzheimer's disease
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"Tracy Young-Pearse"
Mean distance: 14.8 (cluster 32)
 
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Publications

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Hsieh YC, Augur ZM, Arbery M, et al. (2024) Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons. Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Bartosch AMW, Youth EHH, Hansen S, et al. (2023) ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Terzioglu G, Young-Pearse TL. (2023) Microglial function, INPP5D/SHIP1 signaling, and NLRP3 inflammasome activation: implications for Alzheimer's disease. Molecular Neurodegeneration. 18: 89
Chou V, Pearse RV, Aylward AJ, et al. (2023) INPP5D regulates inflammasome activation in human microglia. Nature Communications. 14: 7552
Lee H, Aylward AJ, Pearse RV, et al. (2023) Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer's disease risk gene SORL1. Cell Reports. 112994
Lomoio S, Pandey RS, Rouleau N, et al. (2023) 3D bioengineered neural tissue generated from patient-derived iPSCs mimics time-dependent phenotypes and transcriptional features of Alzheimer's disease. Molecular Psychiatry
Merchant JP, Zhu K, Henrion MYR, et al. (2023) Predictive network analysis identifies JMJD6 and other potential key drivers in Alzheimer's disease. Communications Biology. 6: 503
Young-Pearse TL, Lee H, Hsieh YC, et al. (2023) Moving beyond amyloid and tau to capture the biological heterogeneity of Alzheimer's disease. Trends in Neurosciences
Bartosch AMW, Youth EHH, Hansen S, et al. (2023) ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease. Biorxiv : the Preprint Server For Biology
Wang Z, Jin M, Hong W, et al. (2023) Learnings about Aβ from human brain recommend the use of a live-neuron bioassay for the discovery of next generation Alzheimer's disease immunotherapeutics. Acta Neuropathologica Communications. 11: 39
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