Tracy L. Young-Pearse, Ph.D.
Affiliations: | Neurology | Harvard University/Brigham and Women's |
Area:
Development, schizophrenia, Alzheimer's diseaseGoogle:
"Tracy Young-Pearse"Mean distance: 14.8 (cluster 32) | S | N | B | C | P |
Parents
Sign in to add mentorConstance L. Cepko | grad student | 1997-2004 | Harvard University/Brigham and Women's |
Dennis J. Selkoe | post-doc | 2004-2010 | Harvard University/Brigham and Women's |
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Publications
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Lee H, Pearse RV, Lish AM, et al. (2024) Contributions of genetic variation in astrocytes to cell and molecular mechanisms of risk and resilience to late onset Alzheimer's disease. Biorxiv : the Preprint Server For Biology |
White AJ, Clark KA, Alexander KD, et al. (2024) A stem cell-based assay platform demonstrates alpha-synuclein dependent synaptic dysfunction in patient-derived cortical neurons. Npj Parkinson's Disease. 10: 107 |
Hsieh YC, Augur ZM, Arbery M, et al. (2024) Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons. Alzheimer's & Dementia : the Journal of the Alzheimer's Association |
Bartosch AMW, Youth EHH, Hansen S, et al. (2023) ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience |
Terzioglu G, Young-Pearse TL. (2023) Microglial function, INPP5D/SHIP1 signaling, and NLRP3 inflammasome activation: implications for Alzheimer's disease. Molecular Neurodegeneration. 18: 89 |
Chou V, Pearse RV, Aylward AJ, et al. (2023) INPP5D regulates inflammasome activation in human microglia. Nature Communications. 14: 7552 |
Lee H, Aylward AJ, Pearse RV, et al. (2023) Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer's disease risk gene SORL1. Cell Reports. 112994 |
Lomoio S, Pandey RS, Rouleau N, et al. (2023) 3D bioengineered neural tissue generated from patient-derived iPSCs mimics time-dependent phenotypes and transcriptional features of Alzheimer's disease. Molecular Psychiatry |
Merchant JP, Zhu K, Henrion MYR, et al. (2023) Predictive network analysis identifies JMJD6 and other potential key drivers in Alzheimer's disease. Communications Biology. 6: 503 |
Young-Pearse TL, Lee H, Hsieh YC, et al. (2023) Moving beyond amyloid and tau to capture the biological heterogeneity of Alzheimer's disease. Trends in Neurosciences |