Peter William Gage, Ph.D.

Affiliations: 
The University of New South Wales, Australia 
Area:
Ion channels
Website:
http://www.science.org.au/fellows/memoirs/gage.html
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"Peter Gage"
Bio:

Peter William Gage (1937–2005) was recognised nationally and internationally as one of Australia's leaders in membrane physiology, biophysics and neuroscience. His research on neurotransmission, muscle and the structure–function of ion channels was extraordinarily productive, with over 7,000 citations. A gifted speaker with a great enthusiasm for research and for the introduction of cutting-edge technology, Peter Gage influenced and encouraged a great many research students, postdoctoral fellows and senior colleagues in their scientific careers.

Mean distance: 13.43 (cluster 11)
 
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Publications

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Everitt AB, Seymour VA, Curmi J, et al. (2009) Protein interactions involving the gamma2 large cytoplasmic loop of GABA(A) receptors modulate conductance. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 4361-9
Tierney ML, Luu T, Gage PW. (2008) Functional asymmetry of the conserved cystine loops in alphabetagamma GABA A receptors revealed by the response to GABA activation and drug potentiation. The International Journal of Biochemistry & Cell Biology. 40: 968-79
Gaul S, Ozsarac N, Liu L, et al. (2007) The neuroactive steroids alphaxalone and pregnanolone increase the conductance of single GABAA channels in newborn rat hippocampal neurons. The Journal of Steroid Biochemistry and Molecular Biology. 104: 35-44
Abdellatif Y, Liu D, Gallant EM, et al. (2007) The Mu class glutathione transferase is abundant in striated muscle and is an isoform-specific regulator of ryanodine receptor calcium channels. Cell Calcium. 41: 429-40
Wilson L, Gage P, Ewart G. (2006) Validation of coronavirus E proteins ion channels as targets for antiviral drugs. Advances in Experimental Medicine and Biology. 581: 573-8
Luu T, Gage PW, Tierney ML. (2006) GABA increases both the conductance and mean open time of recombinant GABAA channels co-expressed with GABARAP. The Journal of Biological Chemistry. 281: 35699-708
Wilson L, Gage P, Ewart G. (2006) Hexamethylene amiloride blocks E protein ion channels and inhibits coronavirus replication. Virology. 353: 294-306
Premkumar A, Dong X, Haqshenas G, et al. (2006) Amantadine inhibits the function of an ion channel encoded by GB virus B, but fails to inhibit virus replication. Antiviral Therapy. 11: 289-95
Luu T, Cromer B, Gage PW, et al. (2005) A role for the 2' residue in the second transmembrane helix of the GABA A receptor gamma2S subunit in channel conductance and gating. The Journal of Membrane Biology. 205: 17-28
Premkumar A, Horan CR, Gage PW. (2005) Dengue virus M protein C-terminal peptide (DVM-C) forms ion channels. The Journal of Membrane Biology. 204: 33-8
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