Christopher M. Flores

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
pain, nicotine
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"Christopher Flores"
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SNBCP

Parents

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Ken J. Kellar grad student 1988-1992 Georgetown
Harold Gainer post-doc 1992-1994 NIH
Ken M. Hargreaves post-doc 1994-1997 UMN
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Publications

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Kern DM, Cepeda MS, Flores CM, et al. (2021) Application of Real-World Data and the REWARD Framework to Detect Unknown Benefits of Memantine and Identify Potential Disease Targets for New NMDA Receptor Antagonists. Cns Drugs
Baptista-de-Souza D, Tavares-Ferreira D, Megat S, et al. (2020) Sex differences in the role of atypical PKC within the basolateral nucleus of the amygdala in a mouse hyperalgesic priming model. Neurobiology of Pain (Cambridge, Mass.). 8: 100049
Zhu B, Connolly PJ, Zhang YM, et al. (2020) The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors. Bioorganic & Medicinal Chemistry Letters. 30: 127243
Zhu B, Connolly PJ, Zhang SP, et al. (2020) The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL). Bioorganic & Medicinal Chemistry Letters. 127198
Wyatt RM, Fraser I, Welty N, et al. (2019) Pharmacologic characterization of JNJ-42226314, [1-(4-fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a reversible, selective and potent monoacylglycerol lipase inhibitor. The Journal of Pharmacology and Experimental Therapeutics
Douglass JD, Zhou YX, Wu A, et al. (2019) Erratum: Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity. Journal of Lipid Research. 60: 717
Wall MJ, Subasinghe NL, Winters MP, et al. (2018) Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Ca 2.2) blockers for the treatment of pain. Bioorganic & Medicinal Chemistry Letters
Haanes KA, Labastida-Ramírez A, Chan KY, et al. (2018) Characterization of the trigeminovascular actions of several adenosine A receptor antagonists in an in vivo rat model of migraine. The Journal of Headache and Pain. 19: 41
Manitpisitkul P, Flores CM, Moyer JA, et al. (2018) A multiple-dose double-blind randomized study to evaluate the safety, pharmacokinetics, pharmacodynamics and analgesic efficacy of the TRPV1 antagonist JNJ-39439335 (mavatrep). Scandinavian Journal of Pain. 18: 151-164
Mayorga AJ, Flores CM, Trudeau JJ, et al. (2017) A randomized study to evaluate the analgesic efficacy of a single dose of the TRPV1 antagonist mavatrep in patients with osteoarthritis. Scandinavian Journal of Pain. 17: 134-143
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