Philip J. Laipis
Affiliations: | University of Florida, Gainesville, Gainesville, FL, United States |
Area:
Genetics, Molecular Biology, PathologyWebsite:
https://biochem.med.ufl.edu/research/emeritus-faculty/philip-laipis/Google:
"Philip Laipis"Bio:
DOI: 10.1073/pnas.62.1.289 It is a pleasure to acknowledge the encouragement and advice given by Professors J. Lederberg and I. R. Lehman
Parents
Sign in to add mentor| Adayapalam T. Ganesan | grad student | 1972 | Stanford | |
| (Genetic and biochemical studies on repair and recombination in Bacillus Subtilis.) | ||||
| Arnold Levine | post-doc | 1974 | Princeton (Neurotree) | |
Children
Sign in to add trainee| David A. Jewell | grad student | 1987-1991 | University of Florida College of Medicine (Chemistry Tree) |
| Catherine E. Charron | grad student | 2005 | UF Gainesville |
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Publications
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| Zeile WL, McCune HC, Musson DG, et al. (2017) Maternal Phenylketonuria syndrome: Studies in mice suggest a potential approach to a continuing problem. Pediatric Research |
| Elder I, Fisher Z, Laipis PJ, et al. (2007) Structural and kinetic analysis of proton shuttle residues in the active site of human carbonic anhydrase III. Proteins. 68: 337-43 |
| Embury JE, Charron CE, Martynyuk A, et al. (2007) PKU is a reversible neurodegenerative process within the nigrostriatum that begins as early as 4 weeks of age in Pah(enu2) mice. Brain Research. 1127: 136-50 |
| Yang S, Lee YJ, Kim JM, et al. (2006) A murine model for human sepiapterin-reductase deficiency. American Journal of Human Genetics. 78: 575-87 |
| Zori A, Yang DD, Knapp J, et al. (2006) 214. Dominant-Negative Interference in the Pahenu2 Mouse: Modified Forms of PAH Molecular Therapy. 13: S82-S83 |
| Embury JE, Reep RR, Laipis PJ. (2005) Pathologic and immunohistochemical findings in hypothalamic and mesencephalic regions in the pah(enu2) mouse model for phenylketonuria. Pediatric Research. 58: 283-7 |
| Duda DM, Tu C, Fisher SZ, et al. (2005) Human carbonic anhydrase III: structural and kinetic study of catalysis and proton transfer. Biochemistry. 44: 10046-53 |
| Embury JE, Charron CE, Laipis PJ. (2005) 423. Increased Incidence of Hepatocellular Change and Neoplastic Disease in AAV-WPRE Treated Pahenu2 Mice Molecular Therapy. 11 |
| Charron CE, Perera OP, Porvasnik SL, et al. (2005) 422. Dominant-Negative Interference in the Pahenu2 Mouse Model of PKU: Effectiveness of Vectors Expressing Either Modified Forms of Phenylalanine Hydroxylase (PAH) or Ribozymes Plus a Hardened PAH mRNA Molecular Therapy. 11 |
| Kang SH, Levings PP, Andersen F, et al. (2004) Locus control region elements HS2 and HS3 in combination with chromatin boundaries confer high-level expression of a human beta-globin transgene in a centromeric region. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 9: 1043-53 |