Xun Lan, Ph.D.

Affiliations: 
2012 Integrated Biomedical Science Ohio State University, Columbus, Columbus, OH 
Area:
Molecular Biology
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"Xun Lan"

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Jin Victor grad student 2012 Ohio State
 (Uncovering Transcription Factor Networks by Integrating One Dimensional 'Omics and Three Dimensional Chromatin Structure.)
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Publications

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Glassberg EC, Gao Z, Harpak A, et al. (2018) Evidence for Weak Selective Constraint on Human Gene Expression. Genetics
Hankey W, Chen Z, Bergman MJ, et al. (2018) Chromatin-associated APC regulates gene expression in collaboration with canonical WNT signaling and AP-1. Oncotarget. 9: 31214-31230
Sparvoli D, Richardson E, Osakada H, et al. (2018) Remodeling the Specificity of an Endosomal CORVET Tether Underlies Formation of Regulated Secretory Vesicles in the Ciliate Tetrahymena thermophila. Current Biology : Cb
Harpak A, Lan X, Gao Z, et al. (2017) Frequent nonallelic gene conversion on the human lineage and its effect on the divergence of gene duplicates. Proceedings of the National Academy of Sciences of the United States of America
Kontur C, Kumar S, Lan X, et al. (2016) Whole Genome Sequencing Identifies a Novel Factor Required for Secretory Granule Maturation in Tetrahymena thermophila. G3 (Bethesda, Md.)
Lan X, Pritchard JK. (2016) Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals. Science (New York, N.Y.). 352: 1009-13
Liu B, Fang L, Long R, et al. (2015) iEnhancer-2L: a two-layer predictor for identifying enhancers and their strength by pseudo k-tuple nucleotide composition. Bioinformatics (Oxford, England)
Chen Z, Lan X, Wu D, et al. (2015) Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer. Nature Communications. 6: 8323
Chen Z, Lan X, Thomas-Ahner JM, et al. (2015) Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer. The Embo Journal. 34: 502-16
Banovich NE, Lan X, McVicker G, et al. (2014) Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels. Plos Genetics. 10: e1004663
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