☰

Brett A. Howell, Ph.D.

Affiliations: 
2010 University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Chemical Engineering, Biomedical Engineering, Pharmacy
Google:
"Brett Howell"
Mean distance: (not calculated yet)
 
Tree Publications Grants Similar researchers PubMed Report error

Parents

Sign in to add mentor
Anuj Chauhan grad student 2010 UF Gainesville
 (Drug overdose treatment with liposomes.)

Children

Sign in to add trainee

Collaborators

Sign in to add collaborator
BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Yang K, Battista C, Woodhead JL, et al. (2017) Systems Pharmacology Modeling of Drug-Induced Hyperbilirubinemia: Differentiating Hepatotoxicity and Inhibition of Enzymes/Transporters. Clinical Pharmacology and Therapeutics
Yang K, Guo C, Woodhead JL, et al. (2016) Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury. Journal of Pharmaceutical Sciences. 105: 443-59
Yang Y, Nadanaciva S, Will Y, et al. (2015) MITOsym®: A Mechanistic, Mathematical Model of Hepatocellular Respiration and Bioenergetics. Pharmaceutical Research. 32: 1975-92
Yang K, Woodhead JL, Watkins PB, et al. (2014) Systems pharmacology modeling predicts delayed presentation and species differences in bile acid-mediated troglitazone hepatotoxicity. Clinical Pharmacology and Therapeutics. 96: 589-98
Howell BA, Siler SQ, Watkins PB. (2014) Use of a systems model of drug-induced liver injury (DILIsym(®)) to elucidate the mechanistic differences between acetaminophen and its less-toxic isomer, AMAP, in mice. Toxicology Letters. 226: 163-72
Shoda LK, Woodhead JL, Siler SQ, et al. (2014) Linking physiology to toxicity using DILIsym®, a mechanistic mathematical model of drug-induced liver injury. Biopharmaceutics & Drug Disposition. 35: 33-49
Bhattacharya S, Shoda LK, Zhang Q, et al. (2012) Modeling drug- and chemical-induced hepatotoxicity with systems biology approaches. Frontiers in Physiology. 3: 462
Howell BA, Yang Y, Kumar R, et al. (2012) In vitro to in vivo extrapolation and species response comparisons for drug-induced liver injury (DILI) using DILIsym™: a mechanistic, mathematical model of DILI. Journal of Pharmacokinetics and Pharmacodynamics. 39: 527-41
Howell BA, Chauhan A. (2010) A physiologically based pharmacokinetic (PBPK) model for predicting the efficacy of drug overdose treatment with liposomes in man. Journal of Pharmaceutical Sciences. 99: 3601-19
Howell BA, Chauhan A. (2010) Current and Emerging Detoxification Therapies for Critical Care Materials. 3: 2483-2505
See more...