Tim Thomas

Affiliations: 
Development and Neurobiology The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia 
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"Tim Thomas"
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Bergamasco MI, Vanyai HK, Garnham AL, et al. (2024) Increasing histone acetylation improves sociability and restores learning and memory in KAT6B-haploinsufficient mice. The Journal of Clinical Investigation. 134
Bergamasco MI, Ranathunga N, Abeysekera W, et al. (2024) The histone acetyltransferase KAT6B is required for hematopoietic stem cell development and function. Stem Cell Reports
Mah SYY, Vanyai HK, Li-Wai-Suen CSN, et al. (2024) ING4 and ING5 are essential for histone H3 lysine 14 acetylation and epicardial cell lineage development. Development (Cambridge, England). 151
Rasool D, Burban A, Sharanek A, et al. (2024) PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in the intellectual disability syndrome BFLS. Embo Reports
Sharma S, Chung CY, Uryu S, et al. (2023) Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer. Cell Chemical Biology
Mah SYY, Vanyai HK, Yang Y, et al. (2023) The chromatin reader protein ING5 is required for normal hematopoietic cell numbers in the fetal liver. Frontiers in Immunology. 14: 1119750
Kueh AJ, Bergamasco MI, Quaglieri A, et al. (2023) Stem cell plasticity, acetylation of H3K14, and de novo gene activation rely on KAT7. Cell Reports. 42: 111980
Wichmann J, Pitt C, Eccles S, et al. (2022) Loss of TIP60 (KAT5) abolishes H2AZ lysine 7 acetylation and causes p53, INK4A, and ARF-independent cell cycle arrest. Cell Death & Disease. 13: 627
El-Saafin F, Bergamasco MI, Chen Y, et al. (2022) Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death and Differentiation
Heinlein M, Gandolfo LC, Zhao K, et al. (2022) The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance. Science Immunology. 7: eabb6032
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