Lin-Hua Jiang

Affiliations: 
University of Leeds (United Kingdom) 
Area:
Ion channels in health and disease
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"Lin-Hua Jiang"
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Publications

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Zhang M, Malko P, Jiang LH. (2023) Mechanosensitive Piezo1 channel regulation of microglial cell function and implications to neurodegenerative diseases and neuroinflammation. Neural Regeneration Research. 18: 2385-2386
Jia X, Chen X, Gao C, et al. (2022) Functional cooperation between IK and TRPC1 channels regulates serum-induced vascular smooth muscle cell proliferation via mediating Ca influx and ERK1/2 activation. Cell Proliferation. e13385
Malko P, Jia X, Wood I, et al. (2022) Piezo1 channel-mediated Ca signaling inhibits lipopolysaccharide-induced activation of the NF-κB inflammatory signaling pathway and generation of TNF-α and IL-6 in microglial cells. Glia
Jia X, Gao C, Wang X, et al. (2022) Differential Regulation by Mechanical Stretch of the Expressions of Large-Conductance Ca-Activated K Channel and L-Type Voltage-Dependent Ca Channel in Rat Uterine Smooth Muscle Cells. The Journal of Membrane Biology
Wang L, Roger S, Yang XB, et al. (2021) Role of the store-operated Ca2+ channel in ATP-induced Ca2+ signalling in mesenchymal stem cells and regulation of cell functions. Frontiers in Bioscience (Landmark Edition). 26: 1737-1745
Yu X, Xie Y, Zhang X, et al. (2021) Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel. Cell Reports. 37: 110025
Caseley EA, Muench SP, Jiang LH. (2021) Tyrosine 288 in the extracellular domain of the human P2X7 receptor is critical for receptor function revealed by structural modeling and site-directed mutagenesis. Proteins. 90: 619-624
Jiang LH, Caseley EA, Muench SP, et al. (2021) Structural basis for the functional properties of the P2X7 receptor for extracellular ATP. Purinergic Signalling. 17: 331-344
Malko P, Ding R, Jiang LH. (2021) TRPM2 channel in oxidative stress-induced mitochondrial dysfunction and apoptotic cell death. Advances in Protein Chemistry and Structural Biology. 125: 51-72
Jia X, Yang Q, Gao C, et al. (2021) Stimulation of vascular smooth muscle cell proliferation by stiff matrix via the IK channel-dependent Ca signaling. Journal of Cellular Physiology
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