Lin-Hua Jiang

Affiliations: 
University of Leeds (United Kingdom) 
Area:
Ion channels in health and disease
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"Lin-Hua Jiang"
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Publications

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Zhang M, Malko P, Jiang LH. (2023) Mechanosensitive Piezo1 channel regulation of microglial cell function and implications to neurodegenerative diseases and neuroinflammation. Neural Regeneration Research. 18: 2385-2386
Yin Y, Wei L, Caseley EA, et al. (2023) Leveraging the ATP-P2X7 receptor signalling axis to alleviate traumatic CNS damage and related complications. Medicinal Research Reviews
Jia X, Chen X, Gao C, et al. (2022) Functional cooperation between IK and TRPC1 channels regulates serum-induced vascular smooth muscle cell proliferation via mediating Ca influx and ERK1/2 activation. Cell Proliferation. e13385
Malko P, Jia X, Wood I, et al. (2022) Piezo1 channel-mediated Ca signaling inhibits lipopolysaccharide-induced activation of the NF-κB inflammatory signaling pathway and generation of TNF-α and IL-6 in microglial cells. Glia
Jia X, Gao C, Wang X, et al. (2022) Differential Regulation by Mechanical Stretch of the Expressions of Large-Conductance Ca-Activated K Channel and L-Type Voltage-Dependent Ca Channel in Rat Uterine Smooth Muscle Cells. The Journal of Membrane Biology
Wang L, Roger S, Yang XB, et al. (2021) Role of the store-operated Ca2+ channel in ATP-induced Ca2+ signalling in mesenchymal stem cells and regulation of cell functions. Frontiers in Bioscience (Landmark Edition). 26: 1737-1745
Yu X, Xie Y, Zhang X, et al. (2021) Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel. Cell Reports. 37: 110025
Caseley EA, Muench SP, Jiang LH. (2021) Tyrosine 288 in the extracellular domain of the human P2X7 receptor is critical for receptor function revealed by structural modeling and site-directed mutagenesis. Proteins. 90: 619-624
Jiang LH, Caseley EA, Muench SP, et al. (2021) Structural basis for the functional properties of the P2X7 receptor for extracellular ATP. Purinergic Signalling. 17: 331-344
Malko P, Ding R, Jiang LH. (2021) TRPM2 channel in oxidative stress-induced mitochondrial dysfunction and apoptotic cell death. Advances in Protein Chemistry and Structural Biology. 125: 51-72
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