| Year |
Citation |
Score |
| 2023 |
Zhang M, Malko P, Jiang LH. Mechanosensitive Piezo1 channel regulation of microglial cell function and implications to neurodegenerative diseases and neuroinflammation. Neural Regeneration Research. 18: 2385-2386. PMID 37282460 DOI: 10.4103/1673-5374.371355 |
0.316 |
|
| 2022 |
Jia X, Chen X, Gao C, Wang H, Yang C, Jiang LH, Fan Y. Functional cooperation between IK and TRPC1 channels regulates serum-induced vascular smooth muscle cell proliferation via mediating Ca influx and ERK1/2 activation. Cell Proliferation. e13385. PMID 36562293 DOI: 10.1111/cpr.13385 |
0.304 |
|
| 2022 |
Malko P, Jia X, Wood I, Jiang LH. Piezo1 channel-mediated Ca signaling inhibits lipopolysaccharide-induced activation of the NF-κB inflammatory signaling pathway and generation of TNF-α and IL-6 in microglial cells. Glia. PMID 36447422 DOI: 10.1002/glia.24311 |
0.319 |
|
| 2022 |
Jia X, Gao C, Wang X, Jiang LH, Fan Y. Differential Regulation by Mechanical Stretch of the Expressions of Large-Conductance Ca-Activated K Channel and L-Type Voltage-Dependent Ca Channel in Rat Uterine Smooth Muscle Cells. The Journal of Membrane Biology. PMID 35322298 DOI: 10.1007/s00232-022-00226-0 |
0.33 |
|
| 2021 |
Wang L, Roger S, Yang XB, Jiang LH. Role of the store-operated Ca2+ channel in ATP-induced Ca2+ signalling in mesenchymal stem cells and regulation of cell functions. Frontiers in Bioscience (Landmark Edition). 26: 1737-1745. PMID 34994186 DOI: 10.52586/5065 |
0.364 |
|
| 2021 |
Yu X, Xie Y, Zhang X, Ma C, Liu L, Zhen W, Xu L, Zhang J, Liang Y, Zhao L, Gao X, Yu P, Luo J, Jiang LH, Nie Y, et al. Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel. Cell Reports. 37: 110025. PMID 34788616 DOI: 10.1016/j.celrep.2021.110025 |
0.31 |
|
| 2021 |
Caseley EA, Muench SP, Jiang LH. Tyrosine 288 in the extracellular domain of the human P2X7 receptor is critical for receptor function revealed by structural modeling and site-directed mutagenesis. Proteins. 90: 619-624. PMID 34622987 DOI: 10.1002/prot.26259 |
0.359 |
|
| 2021 |
Jiang LH, Caseley EA, Muench SP, Roger S. Structural basis for the functional properties of the P2X7 receptor for extracellular ATP. Purinergic Signalling. 17: 331-344. PMID 33987781 DOI: 10.1007/s11302-021-09790-x |
0.337 |
|
| 2021 |
Malko P, Ding R, Jiang LH. TRPM2 channel in oxidative stress-induced mitochondrial dysfunction and apoptotic cell death. Advances in Protein Chemistry and Structural Biology. 125: 51-72. PMID 33931144 DOI: 10.1016/bs.apcsb.2020.12.001 |
0.324 |
|
| 2021 |
Jia X, Yang Q, Gao C, Chen X, Li Y, Su H, Zheng Y, Zhang S, Wang Z, Wang H, Jiang LH, Sun Y, Fan Y. Stimulation of vascular smooth muscle cell proliferation by stiff matrix via the IK channel-dependent Ca signaling. Journal of Cellular Physiology. PMID 33650160 DOI: 10.1002/jcp.30349 |
0.33 |
|
| 2020 |
Brisson L, Chadet S, Lopez-Charcas O, Jelassi B, Ternant D, Chamouton J, Lerondel S, Le Pape A, Couillin I, Gombault A, Trovero F, Chevalier S, Besson P, Jiang LH, Roger S. P2X7 Receptor Promotes Mouse Mammary Cancer Cell Invasiveness and Tumour Progression, and Is a Target for Anticancer Treatment. Cancers. 12. PMID 32825056 DOI: 10.3390/Cancers12092342 |
0.363 |
|
| 2020 |
Wang L, Wei LY, Ding R, Feng Y, Li D, Li C, Malko P, Syed Mortadza SA, Wu W, Yin Y, Jiang LH. Predisposition to Alzheimer's and Age-Related Brain Pathologies by PM2.5 Exposure: Perspective on the Roles of Oxidative Stress and TRPM2 Channel. Frontiers in Physiology. 11: 155. PMID 32174842 DOI: 10.3389/Fphys.2020.00155 |
0.325 |
|
| 2020 |
Jia X, Su H, Chen X, Huang Y, Zheng Y, Ji P, Gao C, Gong X, Huang Y, Jiang LH, Fan Y. A critical role of the K 3.1 channel in mechanical stretch-induced proliferation of rat bone marrow-derived mesenchymal stem cells. Journal of Cellular and Molecular Medicine. PMID 32065503 DOI: 10.1111/Jcmm.15014 |
0.398 |
|
| 2020 |
Jiang LH, Roger S. Targeting the P2X7 receptor in microglial cells to prevent brain inflammation. Neural Regeneration Research. 15: 1245-1246. PMID 31960804 DOI: 10.4103/1673-5374.272575 |
0.339 |
|
| 2020 |
Milligan CJ, Jiang LH. Automated Planar Patch-Clamp Recording of P2X Receptors. Methods in Molecular Biology (Clifton, N.J.). 2041: 285-300. PMID 31646497 DOI: 10.1007/978-1-4939-9717-6_21 |
0.47 |
|
| 2020 |
Jiang LH, Roger S. Heterologous Expression and Patch-Clamp Recording of P2X Receptors in HEK293 Cells. Methods in Molecular Biology (Clifton, N.J.). 2041: 261-273. PMID 31646495 DOI: 10.1007/978-1-4939-9717-6_19 |
0.486 |
|
| 2019 |
Wei L, Mousawi F, Li D, Roger S, Li J, Yang X, Jiang LH. Adenosine Triphosphate Release and P2 Receptor Signaling in Piezo1 Channel-Dependent Mechanoregulation. Frontiers in Pharmacology. 10: 1304. PMID 31780935 DOI: 10.3389/Fphar.2019.01304 |
0.501 |
|
| 2019 |
Mousawi F, Peng H, Li J, Sreenivasan P, Roger S, Zhao H, Yang X, Jiang LH. Chemical activation of the Piezo1 channel drives mesenchymal stem cell migration via inducing ATP release and activation of P2 receptor purinergic signalling. Stem Cells (Dayton, Ohio). PMID 31746084 DOI: 10.1002/Stem.3114 |
0.473 |
|
| 2019 |
Di Virgilio F, Jiang LH, Roger S, Falzoni S, Sarti AC, Vultaggio-Poma V, Chiozzi P, Adinolfi E. Structure, function and techniques of investigation of the P2X7 receptor (P2X7R) in mammalian cells. Methods in Enzymology. 629: 115-150. PMID 31727237 DOI: 10.1016/Bs.Mie.2019.07.043 |
0.451 |
|
| 2019 |
Mai C, Mankoo H, Wei L, An X, Li C, Li D, Jiang LH. TRPM2 channel: A novel target for alleviating ischaemia-reperfusion, chronic cerebral hypo-perfusion and neonatal hypoxic-ischaemic brain damage. Journal of Cellular and Molecular Medicine. PMID 31568632 DOI: 10.1111/Jcmm.14679 |
0.431 |
|
| 2019 |
Yu P, Liu Z, Yu X, Ye P, Liu H, Xue X, Yang L, Li Z, Wu Y, Fang C, Zhao YJ, Yang F, Luo JH, Jiang LH, Zhang L, et al. Direct Gating of the TRPM2 Channel by cADPR via Specific Interactions with the ADPR Binding Pocket. Cell Reports. 27: 3684-3695.e4. PMID 31216484 DOI: 10.1016/J.Celrep.2019.05.067 |
0.462 |
|
| 2019 |
Malko P, Mortadza SAS, McWilliam J, Jiang L. TRPM2 Channel in Microglia as a New Player in Neuroinflammation Associated With a Spectrum of Central Nervous System Pathologies. Frontiers in Pharmacology. 10: 239. PMID 30914955 DOI: 10.3389/Fphar.2019.00239 |
0.465 |
|
| 2019 |
An X, Fu Z, Mai C, Wang W, Wei L, Li D, Li C, Jiang LH. Increasing the TRPM2 Channel Expression in Human Neuroblastoma SH-SY5Y Cells Augments the Susceptibility to ROS-Induced Cell Death. Cells. 8. PMID 30625984 DOI: 10.3390/Cells8010028 |
0.423 |
|
| 2018 |
Li X, Jiang LH. A critical role of the transient receptor potential melastatin 2 channel in a positive feedback mechanism for reactive oxygen species-induced delayed cell death. Journal of Cellular Physiology. PMID 30229906 DOI: 10.1002/Jcp.27134 |
0.43 |
|
| 2018 |
Jiang LH, Li X, Mortadza SAS, Lovatt M, Yang W. The TRPM2 channel nexus from oxidative damage to Alzheimer's pathologies: an emerging novel intervention target for age-related dementia. Ageing Research Reviews. PMID 30009973 DOI: 10.1016/J.Arr.2018.07.002 |
0.326 |
|
| 2018 |
Wei L, Syed Mortadza SA, Jiang LH. Melastatin-related transient receptor potential 2 channel in Aβ-induced neuroinflammation: implications to Alzheimer's disease mechanism and development of therapeutics. Neural Regeneration Research. 13: 419-420. PMID 29623922 DOI: 10.4103/1673-5374.228720 |
0.429 |
|
| 2018 |
Wei L, Mortadza SAS, Yan J, Zhang L, Wang L, Yin Y, Li C, Chalon S, Emond P, Belzung C, Li D, Lu C, Roger S, Jiang LH. ATP-activated P2X7 receptor in the pathophysiology of mood disorders and as an emerging target for the development of novel antidepressant therapeutics. Neuroscience and Biobehavioral Reviews. PMID 29453990 DOI: 10.1016/J.Neubiorev.2018.02.005 |
0.399 |
|
| 2018 |
Li X, Jiang LH. Multiple molecular mechanisms form a positive feedback loop driving amyloid β42 peptide-induced neurotoxicity via activation of the TRPM2 channel in hippocampal neurons. Cell Death & Disease. 9: 195. PMID 29416015 DOI: 10.1038/S41419-018-0270-1 |
0.38 |
|
| 2017 |
Li X, Yang W, Jiang LH. Alteration in Intracellular Zn2+ Homeostasis as a Result of TRPM2 Channel Activation Contributes to ROS-Induced Hippocampal Neuronal Death. Frontiers in Molecular Neuroscience. 10: 414. PMID 29311807 DOI: 10.3389/Fnmol.2017.00414 |
0.41 |
|
| 2017 |
Alawieyah Syed Mortadza S, Sim JA, Neubrand VE, Jiang LH. A critical role of TRPM2 channel in Aβ42 -induced microglial activation and generation of tumor necrosis factor-α. Glia. PMID 29143372 DOI: 10.1002/Glia.23265 |
0.424 |
|
| 2017 |
Abuarab N, Munsey TS, Jiang LH, Li J, Sivaprasadarao A. High glucose-induced ROS activates TRPM2 to trigger lysosomal membrane permeabilization and Zn(2+)-mediated mitochondrial fission. Science Signaling. 10. PMID 28765513 DOI: 10.1126/Scisignal.Aal4161 |
0.34 |
|
| 2017 |
Jiang LH, Mousawi F, Yang X, Roger S. ATP-induced Ca(2+)-signalling mechanisms in the regulation of mesenchymal stem cell migration. Cellular and Molecular Life Sciences : Cmls. PMID 28534085 DOI: 10.1007/S00018-017-2545-6 |
0.456 |
|
| 2017 |
Khalid M, Brisson L, Tariq M, Hao Y, Guibon R, Fromont G, Syed Mortadza SA, Mousawi F, Manzoor S, Roger S, Jiang LH. Carcinoma-specific expression of P2Y11 receptor and its contribution in ATP-induced purinergic signalling and cell migration in human hepatocellular carcinoma cells. Oncotarget. PMID 28418839 DOI: 10.18632/Oncotarget.16191 |
0.425 |
|
| 2017 |
Zhao H, Yu Y, Wu X, Liu S, Liu B, Du J, Li B, Jiang L, Feng X. A Role of BK Channel in Regulation of Ca(2+) Channel in Ventricular Myocytes by Substrate Stiffness. Biophysical Journal. 112: 1406-1416. PMID 28402883 DOI: 10.1016/J.Bpj.2017.01.036 |
0.456 |
|
| 2017 |
Mortadza SS, Sim JA, Stacey M, Jiang LH. Signalling mechanisms mediating Zn(2+)-induced TRPM2 channel activation and cell death in microglial cells. Scientific Reports. 7: 45032. PMID 28322340 DOI: 10.1038/srep45032 |
0.321 |
|
| 2017 |
Barniol-Xicota M, Kwak SH, Lee SD, Caseley E, Valverde E, Jiang LH, Kim YC, Vázquez S. Escape from adamantane: Scaffold optimization of novel P2X7 antagonists featuring complex polycycles. Bioorganic & Medicinal Chemistry Letters. PMID 28126517 DOI: 10.1016/J.Bmcl.2017.01.039 |
0.318 |
|
| 2017 |
Yu P, Xue X, Zhang J, Hu X, Wu Y, Jiang LH, Jin H, Luo J, Zhang L, Liu Z, Yang W. Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2. The Journal of General Physiology. PMID 28108595 DOI: 10.1085/Jgp.201611675 |
0.347 |
|
| 2016 |
Caseley EA, Muench SP, Jiang LH. Conformational changes during human P2X7 receptor activation examined by structural modelling and cysteine-based cross-linking studies. Purinergic Signalling. PMID 28025718 DOI: 10.1007/S11302-016-9553-0 |
0.429 |
|
| 2016 |
Caseley EA, Muench SP, Fishwick CW, Jiang LH. Structure-based identification and characterisation of structurally novel human P2X7 receptor antagonists. Biochemical Pharmacology. PMID 27481062 DOI: 10.1016/J.Bcp.2016.07.020 |
0.319 |
|
| 2016 |
Jiang LH, Hao Y, Mousawi F, Peng H, Yang X. Expression of P2 Purinergic Receptors in Mesenchymal Stem Cells and their Roles in Extracellular Nucleotide Regulation of Cell Functions. Journal of Cellular Physiology. PMID 27403750 DOI: 10.1002/Jcp.25484 |
0.438 |
|
| 2016 |
Xu F, Wu X, Jiang LH, Zhao H, Pan J. An organelle K+ channel is required for osmoregulation in Chlamydomonas reinhardtii. Journal of Cell Science. PMID 27311484 DOI: 10.1242/Jcs.188441 |
0.405 |
|
| 2016 |
Peng H, Hao Y, Mousawi F, Roger S, Li J, Sim JA, Ponnambalam S, Yang X, Jiang LH. Purinergic and Store-Operated Ca(2+) Signalling Mechanisms in Mesenchymal Stem Cells and Their roles in ATP-Induced Stimulation of Cell Migration. Stem Cells (Dayton, Ohio). PMID 27038239 DOI: 10.1002/Stem.2370 |
0.429 |
|
| 2016 |
Wei L, Caseley E, Li D, Jiang LH. ATP-induced P2X Receptor-Dependent Large Pore Formation: How Much Do We Know? Frontiers in Pharmacology. 7: 5. PMID 26858647 DOI: 10.3389/Fphar.2016.00005 |
0.382 |
|
| 2015 |
Yu P, Li J, Jiang J, Zhao Z, Hui Z, Zhang J, Zheng Y, Ling D, Wang L, Jiang LH, Luo J, Zhu X, Yang W. A dual role of transient receptor potential melastatin 2 channel in cytotoxicity induced by silica nanoparticles. Scientific Reports. 5: 18171. PMID 26656285 DOI: 10.1038/Srep18171 |
0.414 |
|
| 2015 |
Syed Mortadza SA, Wang L, Li D, Jiang LH. TRPM2 Channel-Mediated ROS-Sensitive Ca(2+) Signaling Mechanisms in Immune Cells. Frontiers in Immunology. 6: 407. PMID 26300888 DOI: 10.3389/Fimmu.2015.00407 |
0.458 |
|
| 2015 |
Caseley EA, Muench SP, Baldwin SA, Simmons K, Fishwick CW, Jiang LH. Docking of competitive inhibitors to the P2X7 receptor family reveals key differences responsible for changes in response between rat and human. Bioorganic & Medicinal Chemistry Letters. PMID 26099538 DOI: 10.1016/J.Bmcl.2015.06.001 |
0.38 |
|
| 2015 |
Li C, Meng L, Li X, Li D, Jiang LH. Non-NMDAR neuronal Ca(2+)-permeable channels in delayed neuronal death and as potential therapeutic targets for ischemic brain damage. Expert Opinion On Therapeutic Targets. 19: 879-92. PMID 25732672 DOI: 10.1517/14728222.2015.1021781 |
0.35 |
|
| 2015 |
Manna PT, Munsey TS, Abuarab N, Li F, Asipu A, Howell G, Sedo A, Yang W, Naylor J, Beech DJ, Jiang LH, Sivaprasadarao A. TRPM2-mediated intracellular Zn2+ release triggers pancreatic β-cell death. The Biochemical Journal. 466: 537-46. PMID 25562606 DOI: 10.1042/Bj20140747 |
0.435 |
|
| 2015 |
Roger S, Jelassi B, Couillin I, Pelegrin P, Besson P, Jiang LH. Understanding the roles of the P2X7 receptor in solid tumour progression and therapeutic perspectives. Biochimica Et Biophysica Acta. 1848: 2584-602. PMID 25450340 DOI: 10.1016/J.Bbamem.2014.10.029 |
0.41 |
|
| 2014 |
Yu W, Jiang LH, Zheng Y, Hu X, Luo J, Yang W. Inactivation of TRPM2 channels by extracellular divalent copper. Plos One. 9: e112071. PMID 25386648 DOI: 10.1371/Journal.Pone.0112071 |
0.397 |
|
| 2014 |
Caseley EA, Muench SP, Roger S, Mao HJ, Baldwin SA, Jiang LH. Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: association with diseases, impact on receptor functions and potential use as diagnosis biomarkers. International Journal of Molecular Sciences. 15: 13344-71. PMID 25079442 DOI: 10.3390/Ijms150813344 |
0.402 |
|
| 2013 |
Jiang LH, Baldwin JM, Roger S, Baldwin SA. Insights into the Molecular Mechanisms Underlying Mammalian P2X7 Receptor Functions and Contributions in Diseases, Revealed by Structural Modeling and Single Nucleotide Polymorphisms. Frontiers in Pharmacology. 4: 55. PMID 23675347 DOI: 10.3389/Fphar.2013.00055 |
0.379 |
|
| 2013 |
Zou J, Ainscough JF, Yang W, Sedo A, Yu SP, Mei ZZ, Sivaprasadarao A, Beech DJ, Jiang LH. A differential role of macrophage TRPM2 channels in Ca²⁺ signaling and cell death in early responses to H₂O₂. American Journal of Physiology. Cell Physiology. 305: C61-9. PMID 23596170 DOI: 10.1152/Ajpcell.00390.2012 |
0.395 |
|
| 2013 |
Jiang LH. Cysteine-based cross-linking approach to study inter-domain interactions in ion channels Methods in Molecular Biology. 998: 267-276. PMID 23529437 DOI: 10.1007/978-1-62703-351-0_21 |
0.356 |
|
| 2013 |
Yang W, Jiang LH. Site-directed mutagenesis to study the structure-function relationships of ion channels. Methods in Molecular Biology (Clifton, N.J.). 998: 257-66. PMID 23529436 DOI: 10.1007/978-1-62703-351-0_20 |
0.374 |
|
| 2013 |
Jelassi B, Anchelin M, Chamouton J, Cayuela ML, Clarysse L, Li J, Goré J, Jiang LH, Roger S. Anthraquinone emodin inhibits human cancer cell invasiveness by antagonizing P2X7 receptors. Carcinogenesis. 34: 1487-96. PMID 23524196 DOI: 10.1093/Carcin/Bgt099 |
0.399 |
|
| 2011 |
Xia R, Samad TA, Btesh J, Jiang LH, Kays I, Stjernborg L, Dekker N. TRPV1 signaling: mechanistic understanding and therapeutic potential. Current Topics in Medicinal Chemistry. 11: 2180-91. PMID 21671876 DOI: 10.2174/156802611796904843 |
0.344 |
|
| 2011 |
Yang W, Manna PT, Zou J, Luo J, Beech DJ, Sivaprasadarao A, Jiang LH. Zinc inactivates melastatin transient receptor potential 2 channels via the outer pore. The Journal of Biological Chemistry. 286: 23789-98. PMID 21602277 DOI: 10.1016/J.Bpj.2011.11.1882 |
0.462 |
|
| 2011 |
Zou J, Yang W, Beech DJ, Jiang LH. A residue in the TRPM2 channel outer pore is crucial in determining species-dependent sensitivity to extracellular acidic pH. PflüGers Archiv : European Journal of Physiology. 462: 293-302. PMID 21505784 DOI: 10.1007/S00424-011-0957-Y |
0.413 |
|
| 2011 |
Bradley HJ, Baldwin JM, Goli GR, Johnson B, Zou J, Sivaprasadarao A, Baldwin SA, Jiang LH. Residues 155 and 348 contribute to the determination of P2X7 receptor function via distinct mechanisms revealed by single-nucleotide polymorphisms. The Journal of Biological Chemistry. 286: 8176-87. PMID 21205829 DOI: 10.1074/Jbc.M110.211284 |
0.427 |
|
| 2010 |
Jiang LH, Yang W, Zou J, Beech DJ. TRPM2 channel properties, functions and therapeutic potentials. Expert Opinion On Therapeutic Targets. 14: 973-88. PMID 20670202 DOI: 10.1517/14728222.2010.510135 |
0.469 |
|
| 2010 |
Yang W, Zou J, Xia R, Vaal ML, Seymour VA, Luo J, Beech DJ, Jiang LH. State-dependent inhibition of TRPM2 channel by acidic pH. The Journal of Biological Chemistry. 285: 30411-8. PMID 20660597 DOI: 10.1074/Jbc.M110.139774 |
0.405 |
|
| 2010 |
Liu L, Zou J, Liu X, Jiang LH, Li J. Inhibition of ATP-induced macrophage death by emodin via antagonizing P2X7 receptor. European Journal of Pharmacology. 640: 15-9. PMID 20452342 DOI: 10.1016/J.Ejphar.2010.04.036 |
0.42 |
|
| 2010 |
Browne LE, Jiang LH, North RA. New structure enlivens interest in P2X receptors. Trends in Pharmacological Sciences. 31: 229-37. PMID 20227116 DOI: 10.1016/J.Tips.2010.02.004 |
0.398 |
|
| 2010 |
Roger S, Mei ZZ, Baldwin JM, Dong L, Bradley H, Baldwin SA, Surprenant A, Jiang LH. Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions. Journal of Psychiatric Research. 44: 347-55. PMID 19931869 DOI: 10.1016/J.Jpsychires.2009.10.005 |
0.453 |
|
| 2010 |
Li Q, Sun B, Wang X, Jin Z, Zhou Y, Dong L, Jiang LH, Rong W. A crucial role for hydrogen sulfide in oxygen sensing via modulating large conductance calcium-activated potassium channels. Antioxidants & Redox Signaling. 12: 1179-89. PMID 19803741 DOI: 10.1089/Ars.2009.2926 |
0.393 |
|
| 2009 |
Mei ZZ, Jiang LH. Requirement for the N-terminal coiled-coil domain for expression and function, but not subunit interaction of, the ADPR-activated TRPM2 channel. The Journal of Membrane Biology. 230: 93-9. PMID 19652898 DOI: 10.1007/S00232-009-9190-4 |
0.4 |
|
| 2009 |
Li DL, Liu X, Xia R, Ross C, Yang X, Jiang LH. Pharmacological properties of ATP-sensitive purinergic receptors expressed in human G292 osteoblastic cells. European Journal of Pharmacology. 617: 12-6. PMID 19577559 DOI: 10.1016/J.Ejphar.2009.06.049 |
0.393 |
|
| 2009 |
Jiang LH. Inhibition of P2X(7) receptors by divalent cations: old action and new insight. European Biophysics Journal : Ebj. 38: 339-46. PMID 18414844 DOI: 10.1007/S00249-008-0315-Y |
0.444 |
|
| 2008 |
Li J, Sukumar P, Milligan CJ, Kumar B, Ma ZY, Munsch CM, Jiang LH, Porter KE, Beech DJ. Interactions, functions, and independence of plasma membrane STIM1 and TRPC1 in vascular smooth muscle cells. Circulation Research. 103: e97-104. PMID 18802022 DOI: 10.1161/Circresaha.108.182931 |
0.354 |
|
| 2008 |
Xia R, Mei ZZ, Mao HJ, Yang W, Dong L, Bradley H, Beech DJ, Jiang LH. Identification of pore residues engaged in determining divalent cationic permeation in transient receptor potential melastatin subtype channel 2. The Journal of Biological Chemistry. 283: 27426-32. PMID 18687688 DOI: 10.1074/Jbc.M801049200 |
0.464 |
|
| 2008 |
Xia R, Mei ZZ, Milligan C, Jiang LH. Inhibitory interaction between P2X4 and GABA(C) rho1 receptors. Biochemical and Biophysical Research Communications. 375: 38-43. PMID 18675255 DOI: 10.1016/J.Bbrc.2008.07.096 |
0.366 |
|
| 2008 |
Young MT, Zhang YH, Cao L, Broomhead H, Jiang LH. Role of the domain encompassing Arg304-Ile328 in rat P2X2 receptor conformation revealed by alterations in complex glycosylation at Asn298. The Biochemical Journal. 416: 137-43. PMID 18616429 DOI: 10.1042/Bj20081182 |
0.349 |
|
| 2008 |
Xu SZ, Sukumar P, Zeng F, Li J, Jairaman A, English A, Naylor J, Ciurtin C, Majeed Y, Milligan CJ, Bahnasi YM, Al-Shawaf E, Porter KE, Jiang LH, Emery P, et al. TRPC channel activation by extracellular thioredoxin. Nature. 451: 69-72. PMID 18172497 DOI: 10.1038/nature06414 |
0.384 |
|
| 2008 |
Liu X, Surprenant A, Mao HJ, Roger S, Xia R, Bradley H, Jiang LH. Identification of key residues coordinating functional inhibition of P2X7 receptors by zinc and copper. Molecular Pharmacology. 73: 252-9. PMID 17959713 DOI: 10.1124/Mol.107.039651 |
0.401 |
|
| 2006 |
Mei ZZ, Xia R, Beech DJ, Jiang LH. Intracellular coiled-coil domain engaged in subunit interaction and assembly of melastatin-related transient receptor potential channel 2. The Journal of Biological Chemistry. 281: 38748-56. PMID 17060318 DOI: 10.1074/Jbc.M607591200 |
0.426 |
|
| 2006 |
Wilkinson WJ, Jiang LH, Surprenant A, North RA. Role of ectodomain lysines in the subunits of the heteromeric P2X2/3 receptor. Molecular Pharmacology. 70: 1159-63. PMID 16840712 DOI: 10.1124/Mol.106.026658 |
0.442 |
|
| 2006 |
Mei ZZ, Mao HJ, Jiang LH. Conserved cysteine residues in the pore region are obligatory for human TRPM2 channel function. American Journal of Physiology. Cell Physiology. 291: C1022-8. PMID 16822940 DOI: 10.1152/Ajpcell.00606.2005 |
0.471 |
|
| 2004 |
Chaumont S, Jiang LH, Penna A, North RA, Rassendren F. Identification of a trafficking motif involved in the stabilization and polarization of P2X receptors. The Journal of Biological Chemistry. 279: 29628-38. PMID 15126501 DOI: 10.1074/jbc.M403940200 |
0.31 |
|
| 2003 |
Jiang LH, Kim M, Spelta V, Bo X, Surprenant A, North RA. Subunit arrangement in P2X receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8903-10. PMID 14523092 DOI: 10.1523/Jneurosci.23-26-08903.2003 |
0.442 |
|
| 2003 |
Bo X, Jiang LH, Wilson HL, Kim M, Burnstock G, Surprenant A, North RA. Pharmacological and biophysical properties of the human P2X5 receptor. Molecular Pharmacology. 63: 1407-16. PMID 12761352 DOI: 10.1124/Mol.63.6.1407 |
0.318 |
|
| 2003 |
Spelta V, Jiang LH, Bailey RJ, Surprenant A, North RA. Interaction between cysteines introduced into each transmembrane domain of the rat P2X2 receptor. British Journal of Pharmacology. 138: 131-6. PMID 12522082 DOI: 10.1038/sj.bjp.0705018 |
0.33 |
|
| 2002 |
Spelta V, Jiang LH, Surprenant A, North RA. Kinetics of antagonist actions at rat P2X2/3 heteromeric receptors. British Journal of Pharmacology. 135: 1524-30. PMID 11906966 DOI: 10.1038/Sj.Bjp.0704591 |
0.344 |
|
| 2001 |
Kim M, Jiang LH, Wilson HL, North RA, Surprenant A. Proteomic and functional evidence for a P2X7 receptor signalling complex. The Embo Journal. 20: 6347-58. PMID 11707406 DOI: 10.1093/Emboj/20.22.6347 |
0.436 |
|
| 2001 |
Jiang LH, Rassendren F, Spelta V, Surprenant A, North RA. Amino acid residues involved in gating identified in the first membrane-spanning domain of the rat P2X(2) receptor. The Journal of Biological Chemistry. 276: 14902-8. PMID 11278888 DOI: 10.1074/jbc.M011327200 |
0.311 |
|
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