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Edwin G. Krebs

University of Washington, Seattle, Seattle, WA 
Protein Phosphorylation
"Edwin Krebs"

(1918 - 2009)
The Nobel Prize in Physiology or Medicine 1992 was awarded jointly to Edmond H. Fischer and Edwin G. Krebs "for their discoveries concerning reversible protein phosphorylation as a biological regulatory mechanism"

Mean distance: 14.86 (cluster 11)
Cross-listing: Chemistry Tree


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Charles C. Price research assistant 1940 UIUC (Chemistry Tree)
Harold Ray Snyder research assistant 1940 UIUC (Chemistry Tree)
Carl F. Cori post-doc 1946-1948 Washington University
Gerty T. Cori post-doc 1946-1948 Washington University


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Jamey Marth grad student (BME Tree)
Jamey Marth grad student (Cell Biology Tree)
Donald John Graves grad student 1959 University of Washington (Chemistry Tree)
Robert J. DeLange grad student 1965 University of Washington (Chemistry Tree)
Thomas Soderling grad student 1966-1970 University of Washington
Natalie G. Ahn post-doc University of Washington (FlyTree)
Joseph A. Beavo post-doc UC Davis (Chemistry Tree)
Arthur M. Edelman post-doc University of Washington
Hagit Eldar-Finkelman post-doc Tel Aviv University
James L. Maller post-doc University of Colorado, Denver (Cell Biology Tree)
Jerome Posner post-doc 1961-1963 University of Washington
Donal A. Walsh post-doc 1966 University of Washington (Chemistry Tree)
Jackie David Corbin post-doc 1971 UC Davis (Chemistry Tree)
Timothy Arthur James Haystead post-doc 1991 University of Washington (Chemistry Tree)
BETA: Related publications


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Hilder TL, Carlson GM, Haystead TA, et al. (2005) Caspase-3 dependent cleavage and activation of skeletal muscle phosphorylase b kinase. Molecular and Cellular Biochemistry. 275: 233-42
Homma MK, Wada I, Suzuki T, et al. (2005) CK2 phosphorylation of eukaryotic translation initiation factor 5 potentiates cell cycle progression. Proceedings of the National Academy of Sciences of the United States of America. 102: 15688-93
Homma MK, Li D, Krebs EG, et al. (2002) Association and regulation of casein kinase 2 activity by adenomatous polyposis coli protein. Proceedings of the National Academy of Sciences of the United States of America. 99: 5959-64
Arrow KJ, Axelrod J, Benacerraf B, et al. (2001) Nobel laureates' letter to President Bush. The Washington Post. A02
Graves JD, Draves KE, Gotoh Y, et al. (2001) Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/Fas-induced apoptosis. The Journal of Biological Chemistry. 276: 14909-15
Krebs EG, Graves JD. (2000) Interactions between protein kinases and proteases in cellular signaling and regulation. Advances in Enzyme Regulation. 40: 441-70
Zhao AZ, Shinohara MM, Huang D, et al. (2000) Leptin induces insulin-like signaling that antagonizes cAMP elevation by glucagon in hepatocytes. The Journal of Biological Chemistry. 275: 11348-54
Li D, Dobrowolska G, Aicher LD, et al. (1999) Expression of the casein kinase 2 subunits in Chinese hamster ovary and 3T3 L1 cells provides information on the role of the enzyme in cell proliferation and the cell cycle. The Journal of Biological Chemistry. 274: 32988-96
Wright JH, Munar E, Jameson DR, et al. (1999) Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 96: 11335-40
Graves JD, Krebs EG. (1999) Protein phosphorylation and signal transduction. Pharmacology & Therapeutics. 82: 111-21
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