Michael J. Difilippantonio, Ph.D.

Affiliations: 
1998- National Cancer Institute, Rockville, MD, United States 
Area:
Cancer, Molecular Cytogenetics
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"Michael Difilippantonio"
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Parents

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David Christian Ward research assistant 1990-1992 Yale School of Medicine (Chemistry Tree)
David G. Schatz grad student 1992-1997 Yale University Graduate School
Thomas Ried post-doc 1998-2000 National Cancer Institute (Chemistry Tree)

Collaborators

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Andre Nussenzweig collaborator National Cancer Institute (Cell Biology Tree)
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Publications

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Patkar S, Heselmeyer-Haddad K, Auslander N, et al. (2021) Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies. Genome Medicine. 13: 93
McNamara G, Difilippantonio M, Ried T, et al. (2017) Microscopy and Image Analysis. Current Protocols in Human Genetics. 94: 4.4.1-4.4.89
Grade M, Difilippantonio MJ, Camps J. (2015) Patterns of chromosomal aberrations in solid tumors Recent Results in Cancer Research. 200: 115-142
Padilla-Nash HM, McNeil NE, Yi M, et al. (2013) Aneuploidy, oncogene amplification and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells. Carcinogenesis. 34: 1929-39
Camps J, Pitt JJ, Emons G, et al. (2013) Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer. Cancer Research. 73: 2003-13
Gaedcke J, Grade M, Camps J, et al. (2012) The rectal cancer microRNAome--microRNA expression in rectal cancer and matched normal mucosa. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4919-30
Ried T, Hu Y, Difilippantonio MJ, et al. (2012) The consequences of chromosomal aneuploidy on the transcriptome of cancer cells. Biochimica Et Biophysica Acta. 1819: 784-93
Hummon AB, Pitt JJ, Camps J, et al. (2012) Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells. Molecular Cancer. 11: 1
Derfoul A, Juan AH, Difilippantonio MJ, et al. (2011) Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase. Carcinogenesis. 32: 1607-14
Gemoll T, Roblick UJ, Szymczak S, et al. (2011) HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers. Cellular and Molecular Life Sciences : Cmls. 68: 3261-74
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