James Alexander Thomson, V.M.D., Ph.D., Diplomate A.C.V.P.
|University of Wisconsin, Madison, Madison, WI|
|University of California, Santa Barbara, Santa Barbara, CA, United States|
|2009-||Regenerative Biology||The Morgrdige Institute for Research|
Area:Embryonic Stem Cell, Regenerative Biology, Induce Pluripotent Stem Cell,
Father of primate pluripotent stem cell biology. First to isolate and clone non-human primate and human embryonic stem cells. First to conceive and prove that iPSCs can be generated from human terminally differentiated tissue.
Mean distance: 35622
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|Chu LF, Mamott D, Ni Z, et al. (2019) An In Vitro Human Segmentation Clock Model Derived from Embryonic Stem Cells. Cell Reports. 28: 2247-2255.e5|
|Bacher R, Leng N, Chu LF, et al. (2018) Trendy: segmented regression analysis of expression dynamics in high-throughput ordered profiling experiments. Bmc Bioinformatics. 19: 380|
|Bacher R, Chu LF, Leng N, et al. (2017) SCnorm: robust normalization of single-cell RNA-seq data. Nature Methods|
|Chu LF, Leng N, Zhang J, et al. (2016) Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm. Genome Biology. 17: 173|
|Leng N, Choi J, Chu LF, et al. (2016) OEFinder: A user interface to identify and visualize ordering effects in single-cell RNA-seq data. Bioinformatics (Oxford, England)|
|Schwartz MP, Hou Z, Propson NE, et al. (2015) Human pluripotent stem cell-derived neural constructs for predicting neural toxicity. Proceedings of the National Academy of Sciences of the United States of America|
|Leng N, Chu LF, Barry C, et al. (2015) Oscope identifies oscillatory genes in unsynchronized single-cell RNA-seq experiments. Nature Methods. 12: 947-50|
|Leng N, Li Y, McIntosh BE, et al. (2015) EBSeq-HMM: a Bayesian approach for identifying gene-expression changes in ordered RNA-seq experiments. Bioinformatics (Oxford, England)|
|Hou Z, Jiang P, Swanson SA, et al. (2015) A cost-effective RNA sequencing protocol for large-scale gene expression studies. Scientific Reports. 5: 9570|
|Dixon JR, Jung I, Selvaraj S, et al. (2015) Chromatin architecture reorganization during stem cell differentiation. Nature. 518: 331-6|