| Year |
Citation |
Score |
| 2006 |
Losey HC, Ruthenburg AJ, Verdine GL. Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA. Nature Structural & Molecular Biology. 13: 153-9. PMID 16415880 DOI: 10.1038/Nsmb1047 |
0.543 |
|
| 2004 |
Mulichak AM, Lu W, Losey HC, Walsh CT, Garavito RM. Crystal structure of vancosaminyltransferase GtfD from the vancomycin biosynthetic pathway: interactions with acceptor and nucleotide ligands. Biochemistry. 43: 5170-80. PMID 15122882 DOI: 10.1021/Bi036130C |
0.526 |
|
| 2003 |
Walsh C, Freel Meyers CL, Losey HC. Antibiotic glycosyltransferases: antibiotic maturation and prospects for reprogramming. Journal of Medicinal Chemistry. 46: 3425-36. PMID 12877577 DOI: 10.1021/Jm030257I |
0.63 |
|
| 2003 |
Mulichak AM, Losey HC, Lu W, Wawrzak Z, Walsh CT, Garavito RM. Structure of the TDP-epi-vancosaminyltransferase GtfA from the chloroeremomycin biosynthetic pathway. Proceedings of the National Academy of Sciences of the United States of America. 100: 9238-43. PMID 12874381 DOI: 10.1073/Pnas.1233577100 |
0.56 |
|
| 2003 |
Walsh CT, Losey HC, Freel Meyers CL. Antibiotic glycosyltransferases. Biochemical Society Transactions. 31: 487-92. PMID 12773141 DOI: 10.1042/ |
0.497 |
|
| 2002 |
Losey HC, Jiang J, Biggins JB, Oberthür M, Ye XY, Dong SD, Kahne D, Thorson JS, Walsh CT. Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides. Chemistry & Biology. 9: 1305-14. PMID 12498883 DOI: 10.1016/S1074-5521(02)00270-3 |
0.528 |
|
| 2002 |
Dong SD, Oberthür M, Losey HC, Anderson JW, Eggert US, Peczuh MW, Walsh CT, Kahne D. The structural basis for induction of VanB resistance. Journal of the American Chemical Society. 124: 9064-5. PMID 12149006 DOI: 10.1021/Ja026342H |
0.477 |
|
| 2002 |
Merkel AB, Temple GK, Burkart MD, Losey HC, Beis K, Walsh CT, Naismith JH. Purification, crystallization and preliminary structural studies of dTDP-4-keto-6-deoxy-glucose-5-epimerase (EvaD) from Amycolatopsis orientalis, the fourth enzyme in the dTDP-L-epivancosamine biosynthetic pathway. Acta Crystallographica. Section D, Biological Crystallography. 58: 1226-8. PMID 12077451 DOI: 10.1107/S0907444902007382 |
0.624 |
|
| 2001 |
Walsh CT, Chen H, Keating TA, Hubbard BK, Losey HC, Luo L, Marshall CG, Miller DA, Patel HM. Tailoring enzymes that modify nonribosomal peptides during and after chain elongation on NRPS assembly lines. Current Opinion in Chemical Biology. 5: 525-34. PMID 11578925 DOI: 10.1016/S1367-5931(00)00235-0 |
0.642 |
|
| 2001 |
Mulichak AM, Losey HC, Walsh CT, Garavito RM. Structure of the UDP-glucosyltransferase GtfB that modifies the heptapeptide aglycone in the biosynthesis of vancomycin group antibiotics. Structure (London, England : 1993). 9: 547-57. PMID 11470430 DOI: 10.1016/S0969-2126(01)00616-5 |
0.564 |
|
| 2001 |
Losey HC, Peczuh MW, Chen Z, Eggert US, Dong SD, Pelczer I, Kahne D, Walsh CT. Tandem action of glycosyltransferases in the maturation of vancomycin and teicoplanin aglycones: novel glycopeptides. Biochemistry. 40: 4745-55. PMID 11294642 DOI: 10.1021/Bi010050W |
0.541 |
|
| 2000 |
Chen H, Thomas MG, Hubbard BK, Losey HC, Walsh CT, Burkart MD. Deoxysugars in glycopeptide antibiotics: enzymatic synthesis of TDP-L-epivancosamine in chloroeremomycin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 97: 11942-7. PMID 11035791 DOI: 10.1073/Pnas.210395097 |
0.619 |
|
| 2000 |
Ehmann DE, Shaw-Reid CA, Losey HC, Walsh CT. The EntF and EntE adenylation domains of Escherichia coli enterobactin synthetase: sequestration and selectivity in acyl-AMP transfers to thiolation domain cosubstrates. Proceedings of the National Academy of Sciences of the United States of America. 97: 2509-14. PMID 10688898 DOI: 10.1073/Pnas.040572897 |
0.645 |
|
| 1999 |
Shaw-Reid CA, Kelleher NL, Losey HC, Gehring AM, Berg C, Walsh CT. Assembly line enzymology by multimodular nonribosomal peptide synthetases: the thioesterase domain of E. coli EntF catalyzes both elongation and cyclolactonization. Chemistry & Biology. 6: 385-400. PMID 10375542 DOI: 10.1016/S1074-5521(99)80050-7 |
0.628 |
|
| 1999 |
Ibba M, Losey HC, Kawarabayasi Y, Kikuchi H, Bunjun S, Söll D. Substrate recognition by class I lysyl-tRNA synthetases: a molecular basis for gene displacement. Proceedings of the National Academy of Sciences of the United States of America. 96: 418-23. PMID 9892648 DOI: 10.1073/Pnas.96.2.418 |
0.316 |
|
| 1999 |
Shaw-Reid CA, Kelleher NL, Losey HC, Gehring AM, Berg C, Walsh CT. Erratum: Assembly line enzymology by multimodular nonribosomal peptide synthetases: The thioesterase domain of E. coli EntF catalyzes both elongation and cyclolactonization (Chemistry and Biology (1999) 6 (385-400)) Chemistry & Biology. 6. DOI: 10.1016/S1074-5521(00)80026-5 |
0.594 |
|
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