Year |
Citation |
Score |
2021 |
Dehkordi SK, Walker J, Sah E, Bennett E, Atrian F, Frost B, Woost B, Bennett RE, Orr TC, Zhou Y, Andhey PS, Colonna M, Sudmant PH, Xu P, Wang M, ... ... Orr ME, et al. Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology. Nature Aging. 1: 1107-1116. PMID 35531351 DOI: 10.1038/s43587-021-00142-3 |
0.316 |
|
2019 |
Baeuerle E, Zhang N, Musi N, Orr ME. WHOLE-BODY TAU-KNOCKOUT MICE DEVELOP AGE-ASSOCIATED METABOLIC DYSFUNCTION AND OBESITY Innovation in Aging. 3: S89-S89. DOI: 10.1093/Geroni/Igz038.341 |
0.34 |
|
2018 |
Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME. Tau protein aggregation is associated with cellular senescence in the brain. Aging Cell. e12840. PMID 30126037 DOI: 10.1111/Acel.12840 |
0.441 |
|
2017 |
Orr ME, Sullivan AC, Frost B. A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies. Trends in Pharmacological Sciences. PMID 28455089 DOI: 10.1016/J.Tips.2017.03.011 |
0.389 |
|
2017 |
Orr ME, Carlson GA, Musi N. Tau Aggregation Induces Cellular Senescence In The Brain Alzheimers & Dementia. 13: 679. DOI: 10.1016/J.Jalz.2017.06.842 |
0.325 |
|
2016 |
Orr ME, Garbarino VR, Salinas A, Buffenstein R. Extended Postnatal Brain Development in the Longest-Lived Rodent: Prolonged Maintenance of Neotenous Traits in the Naked Mole-Rat Brain. Frontiers in Neuroscience. 10: 504. PMID 27877105 DOI: 10.3389/Fnins.2016.00504 |
0.345 |
|
2016 |
Triplett JC, Swomley AM, Kirk J, Grimes KM, Lewis KN, Orr ME, Rodriguez KA, Cai J, Klein JB, Buffenstein R, Butterfield DA. Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat. Neurochemical Research. PMID 26935741 DOI: 10.1007/S11064-016-1877-1 |
0.344 |
|
2015 |
Lefcort F, Chaverra M, George L, Carleson G, Orr M, Grindeland A. Mouse models for Familial Dysautonomia reveal underlying cellular and molecular mechanisms that cause the human disease. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 47: 4. PMID 26531342 DOI: 10.1016/J.Ijdevneu.2015.04.021 |
0.535 |
|
2015 |
Triplett JC, Tramutola A, Swomley A, Kirk J, Grimes K, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Perluigi M, Buffenstein R, Butterfield DA. Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity. Biochimica Et Biophysica Acta. 1852: 2213-24. PMID 26248058 DOI: 10.1016/J.Bbadis.2015.08.002 |
0.325 |
|
2015 |
Triplett JC, Swomley A, Kirk J, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Buffenstein R, Butterfield DA. Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat. Journal of Neurochemistry. 134: 538-50. PMID 25940666 DOI: 10.1111/Jnc.13149 |
0.332 |
|
2015 |
Orr ME, Garbarino VR, Salinas A, Buffenstein R. Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent. Neurobiology of Aging. 36: 1496-504. PMID 25576082 DOI: 10.1016/J.Neurobiolaging.2014.12.004 |
0.39 |
|
2015 |
Talboom JS, Orr M, Caccamo A, Oddo S. P3-043: Chemogenetic facilitation of neuronal depolarization ameliorates Alzheimer's disease-like cognitive deficits Alzheimer's & Dementia. 11: P634-P635. DOI: 10.1016/J.Jalz.2015.06.909 |
0.352 |
|
2014 |
Orr ME, Salinas A, Buffenstein R, Oddo S. Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology. Neurobiology of Aging. 35: 1233-42. PMID 24411482 DOI: 10.1016/J.Neurobiolaging.2013.12.006 |
0.317 |
|
2014 |
Medina DX, Orr ME, Oddo S. Accumulation of C-terminal fragments of transactive response DNA-binding protein 43 leads to synaptic loss and cognitive deficits in human TDP-43 transgenic mice. Neurobiology of Aging. 35: 79-87. PMID 23954172 DOI: 10.1016/J.Neurobiolaging.2013.07.006 |
0.348 |
|
2013 |
George L, Chaverra M, Wolfe L, Thorne J, Close-Davis M, Eibs A, Riojas V, Grindeland A, Orr M, Carlson GA, Lefcort F. Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: 18698-703. PMID 24173031 DOI: 10.1073/Pnas.1308596110 |
0.537 |
|
2013 |
Orr ME, Oddo S. Autophagic/lysosomal dysfunction in Alzheimer's disease. Alzheimer's Research & Therapy. 5: 53. PMID 24171818 DOI: 10.1186/Alzrt217 |
0.361 |
|
2013 |
Orr M, Oddo S. P1-105: The role of autophagy in Alzheimer's disease Alzheimer's & Dementia. 9: P189-P189. DOI: 10.1016/J.Jalz.2013.05.327 |
0.331 |
|
2012 |
Orr ME, Pitstick R, Canine B, Ashe KH, Carlson GA. Genotype-specific differences between mouse CNS stem cell lines expressing frontotemporal dementia mutant or wild type human tau. Plos One. 7: e39328. PMID 22723997 DOI: 10.1371/Journal.Pone.0039328 |
0.378 |
|
2008 |
Orr ME, Giri RK, Ashe KH, Carlson GA. P1-095: CNS stem cell lines from tau transgenic mice as models for frontotemporal dementia Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.681 |
0.328 |
|
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