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Paul Cohen, Ph.D. - Publications

Area:
molecular mechanisms that regulate food intake and body weight
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cohen P, Kajimura S. The cellular and functional complexity of thermogenic fat. Nature Reviews. Molecular Cell Biology. PMID 33758402 DOI: 10.1038/s41580-021-00350-0  0.88
2021 Maguire OA, Ackerman SE, Szwed SK, Maganti AV, Marchildon F, Huang X, Kramer DJ, Rosas-Villegas A, Gelfer RG, Turner LE, Ceballos V, Hejazi A, Samborska B, Rahbani JF, Dykstra CB, ... ... Cohen P, et al. Creatine-mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer. Cell Metabolism. PMID 33596409 DOI: 10.1016/j.cmet.2021.01.018  0.84
2020 Kazak L, Cohen P. Creatine metabolism: energy homeostasis, immunity and cancer biology. Nature Reviews. Endocrinology. PMID 32493980 DOI: 10.1038/s41574-020-0365-5  0.84
2019 Schneeberger M, Parolari L, Das Banerjee T, Bhave V, Wang P, Patel B, Topilko T, Wu Z, Choi CHJ, Yu X, Pellegrino K, Engel EA, Cohen P, Renier N, Friedman JM, et al. Regulation of Energy Expenditure by Brainstem GABA Neurons. Cell. PMID 31257028 DOI: 10.1016/j.cell.2019.05.048  0.88
2019 Meagher NS, Wang L, Rambau PF, Intermaggio MP, Huntsman DG, Wilkens LR, El-Bahrawy MA, Ness RB, Odunsi K, Steed H, Herpel E, Anglesio MS, Zhang B, Lambie N, Swerdlow AJ, ... ... Cohen P, et al. A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 31239549 DOI: 10.1038/s41379-019-0302-0  0.36
2019 Wang W, Ishibashi J, Trefely S, Shao M, Cowan AJ, Sakers A, Lim HW, O'Connor S, Doan MT, Cohen P, Baur JA, King MT, Veech RL, Won KJ, Rabinowitz JD, et al. A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate. Cell Metabolism. PMID 31155495 DOI: 10.1016/j.cmet.2019.05.005  0.48
2018 Hasegawa Y, Ikeda K, Chen Y, Alba DL, Stifler D, Shinoda K, Hosono T, Maretich P, Yang Y, Ishigaki Y, Chi J, Cohen P, Koliwad SK, Kajimura S. Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis. Cell Metabolism. 27: 180-194.e6. PMID 29320702 DOI: 10.1016/j.cmet.2017.12.005  0.88
2018 Khandekar MJ, Banks AS, Laznik-Bogoslavski D, White JP, Choi JH, Kazak L, Lo JC, Cohen P, Wong KK, Kamenecka TM, Griffin PR, Spiegelman BM. Noncanonical agonist PPARγ ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 29295932 DOI: 10.1073/pnas.1717776115  0.84
2017 Garsed DW, Alsop K, Fereday S, Emmanuel C, Kennedy C, Etemadmoghadam D, Gao B, Gebski V, Garès V, Christie EL, Wouters MC, Milne K, George J, Patch AM, Li J, ... ... Cohen PA, et al. Homologous Recombination DNA Repair Pathway Disruption and Retinoblastoma Protein Loss are Associated with Exceptional Survival in High-Grade Serous Ovarian Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29061645 DOI: 10.1158/1078-0432.CCR-17-1621  0.36
2017 Pereira MMA, Mahú I, Seixas E, Martinéz-Sánchez N, Kubasova N, Pirzgalska RM, Cohen P, Dietrich MO, López M, Bernardes GJL, Domingos AI. Corrigendum: A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages. Nature Communications. 8: 15673. PMID 28513619 DOI: 10.1038/ncomms15673  0.6
2017 Pereira MM, Mahú I, Seixas E, Martinéz-Sánchez N, Kubasova N, Pirzgalska RM, Cohen P, Dietrich MO, López M, Bernardes GJ, Domingos AI. A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages. Nature Communications. 8: 14967. PMID 28367972 DOI: 10.1038/ncomms14967  0.6
2016 Cohen P, Spiegelman BM. Cell biology of fat storage. Molecular Biology of the Cell. 27: 2523-7. PMID 27528697 DOI: 10.1091/mbc.E15-10-0749  0.52
2016 Svensson KJ, Long JZ, Jedrychowski MP, Cohen P, Lo JC, Serag S, Kir S, Shinoda K, Tartaglia JA, Rao RR, Chédotal A, Kajimura S, Gygi SP, Spiegelman BM. A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function. Cell Metabolism. PMID 26876562 DOI: 10.1016/j.cmet.2016.01.008  0.88
2015 Kazak L, Chouchani ET, Jedrychowski MP, Erickson BK, Shinoda K, Cohen P, Vetrivelan R, Lu GZ, Laznik-Bogoslavski D, Hasenfuss SC, Kajimura S, Gygi SP, Spiegelman BM. A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat. Cell. 163: 643-55. PMID 26496606 DOI: 10.1016/j.cell.2015.09.035  0.88
2015 Cohen P, Spiegelman BM. Brown and Beige Fat: Molecular Parts of a Thermogenic Machine. Diabetes. 64: 2346-51. PMID 26050670 DOI: 10.2337/db15-0318  0.52
2015 Cipolletta D, Cohen P, Spiegelman BM, Benoist C, Mathis D. Appearance and disappearance of the mRNA signature characteristic of Treg cells in visceral adipose tissue: age, diet, and PPARγ effects. Proceedings of the National Academy of Sciences of the United States of America. 112: 482-7. PMID 25550516 DOI: 10.1073/pnas.1423486112  0.88
2014 Kir S, White JP, Kleiner S, Kazak L, Cohen P, Baracos VE, Spiegelman BM. Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia. Nature. 513: 100-4. PMID 25043053 DOI: 10.1038/nature13528  0.88
2014 Kong X, Banks A, Liu T, Kazak L, Rao RR, Cohen P, Wang X, Yu S, Lo JC, Tseng YH, Cypess AM, Xue R, Kleiner S, Kang S, Spiegelman BM, et al. IRF4 is a key thermogenic transcriptional partner of PGC-1α. Cell. 158: 69-83. PMID 24995979 DOI: 10.1016/j.cell.2014.04.049  0.88
2014 Lo JC, Ljubicic S, Leibiger B, Kern M, Leibiger IB, Moede T, Kelly ME, Chatterjee Bhowmick D, Murano I, Cohen P, Banks AS, Khandekar MJ, Dietrich A, Flier JS, Cinti S, et al. Adipsin is an adipokine that improves β cell function in diabetes. Cell. 158: 41-53. PMID 24995977 DOI: 10.1016/j.cell.2014.06.005  0.88
2014 Cohen P, Levy JD, Zhang Y, Frontini A, Kolodin DP, Svensson KJ, Lo JC, Zeng X, Ye L, Khandekar MJ, Wu J, Gunawardana SC, Banks AS, Camporez JP, Jurczak MJ, et al. Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch. Cell. 156: 304-16. PMID 24439384 DOI: 10.1016/j.cell.2013.12.021  0.88
2013 Ye L, Wu J, Cohen P, Kazak L, Khandekar MJ, Jedrychowski MP, Zeng X, Gygi SP, Spiegelman BM. Fat cells directly sense temperature to activate thermogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 12480-5. PMID 23818608 DOI: 10.1073/pnas.1310261110  0.88
2013 Wu J, Cohen P, Spiegelman BM. Adaptive thermogenesis in adipocytes: is beige the new brown? Genes & Development. 27: 234-50. PMID 23388824 DOI: 10.1101/gad.211649.112  0.88
2012 Ye L, Kleiner S, Wu J, Sah R, Gupta RK, Banks AS, Cohen P, Khandekar MJ, Boström P, Mepani RJ, Laznik D, Kamenecka TM, Song X, Liedtke W, Mootha VK, et al. TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis. Cell. 151: 96-110. PMID 23021218 DOI: 10.1016/j.cell.2012.08.034  0.88
2012 Fox CS, White CC, Lohman K, Heard-Costa N, Cohen P, Zhang Y, Johnson AD, Emilsson V, Liu CT, Chen YD, Taylor KD, Allison M, Budoff M, Rotter JI, et al. Genome-wide association of pericardial fat identifies a unique locus for ectopic fat. Plos Genetics. 8: e1002705. PMID 22589742 DOI: 10.1371/journal.pgen.1002705  0.88
2012 Gupta RK, Mepani RJ, Kleiner S, Lo JC, Khandekar MJ, Cohen P, Frontini A, Bhowmick DC, Ye L, Cinti S, Spiegelman BM. Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells. Cell Metabolism. 15: 230-9. PMID 22326224 DOI: 10.1016/j.cmet.2012.01.010  0.88
2011 Khandekar MJ, Cohen P, Spiegelman BM. Molecular mechanisms of cancer development in obesity. Nature Reviews. Cancer. 11: 886-95. PMID 22113164 DOI: 10.1038/nrc3174  0.88
2011 Seale P, Conroe HM, Estall J, Kajimura S, Frontini A, Ishibashi J, Cohen P, Cinti S, Spiegelman BM. Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice. The Journal of Clinical Investigation. 121: 96-105. PMID 21123942 DOI: 10.1172/JCI44271  0.88
2008 Birsoy K, Soukas A, Torrens J, Ceccarini G, Montez J, Maffei M, Cohen P, Fayzikhodjaeva G, Viale A, Socci ND, Friedman JM. Cellular program controlling the recovery of adipose tissue mass: An in vivo imaging approach. Proceedings of the National Academy of Sciences of the United States of America. 105: 12985-90. PMID 18753616 DOI: 10.1073/pnas.0805621105  0.88
2005 Cohen P, Yang G, Yu X, Soukas AA, Wolfish CS, Friedman JM, Li C. Induction of leptin receptor expression in the liver by leptin and food deprivation. The Journal of Biological Chemistry. 280: 10034-9. PMID 15644325 DOI: 10.1074/jbc.M413684200  0.88
2005 Dobrzyn A, Dobrzyn P, Lee SH, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM. Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle. American Journal of Physiology. Endocrinology and Metabolism. 288: E599-607. PMID 15562249 DOI: 10.1152/ajpendo.00439.2004  0.88
2004 Cohen P, Friedman JM. Leptin and the control of metabolism: role for stearoyl-CoA desaturase-1 (SCD-1). The Journal of Nutrition. 134: 2455S-2463S. PMID 15333742  0.88
2004 Dobrzyn P, Dobrzyn A, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver. Proceedings of the National Academy of Sciences of the United States of America. 101: 6409-14. PMID 15096593 DOI: 10.1073/pnas.0401627101  0.88
2004 Asilmaz E, Cohen P, Miyazaki M, Dobrzyn P, Ueki K, Fayzikhodjaeva G, Soukas AA, Kahn CR, Ntambi JM, Socci ND, Friedman JM. Site and mechanism of leptin action in a rodent form of congenital lipodystrophy. The Journal of Clinical Investigation. 113: 414-24. PMID 14755338 DOI: 10.1172/JCI19511  0.88
2003 Cohen P, Ntambi JM, Friedman JM. Stearoyl-CoA desaturase-1 and the metabolic syndrome. Current Drug Targets. Immune, Endocrine and Metabolic Disorders. 3: 271-80. PMID 14683458  0.88
2003 Miyazaki M, Jacobson MJ, Man WC, Cohen P, Asilmaz E, Friedman JM, Ntambi JM. Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors. The Journal of Biological Chemistry. 278: 33904-11. PMID 12815040 DOI: 10.1074/jbc.M304724200  0.88
2003 Chiellini C, Costa M, Novelli SE, Amri EZ, Benzi L, Bertacca A, Cohen P, Del Prato S, Friedman JM, Maffei M. Identification of cathepsin K as a novel marker of adiposity in white adipose tissue. Journal of Cellular Physiology. 195: 309-21. PMID 12652657 DOI: 10.1002/jcp.10253  0.88
2002 Ntambi JM, Miyazaki M, Stoehr JP, Lan H, Kendziorski CM, Yandell BS, Song Y, Cohen P, Friedman JM, Attie AD. Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proceedings of the National Academy of Sciences of the United States of America. 99: 11482-6. PMID 12177411 DOI: 10.1073/pnas.132384699  0.88
2002 Cohen P, Miyazaki M, Socci ND, Hagge-Greenberg A, Liedtke W, Soukas AA, Sharma R, Hudgins LC, Ntambi JM, Friedman JM. Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science (New York, N.Y.). 297: 240-3. PMID 12114623 DOI: 10.1126/science.1071527  0.88
2001 Cohen P, Zhao C, Cai X, Montez JM, Rohani SC, Feinstein P, Mombaerts P, Friedman JM. Selective deletion of leptin receptor in neurons leads to obesity. The Journal of Clinical Investigation. 108: 1113-21. PMID 11602618 DOI: 10.1172/JCI13914  0.88
2000 Soukas A, Cohen P, Socci ND, Friedman JM. Leptin-specific patterns of gene expression in white adipose tissue. Genes & Development. 14: 963-80. PMID 10783168  0.88
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