Year |
Citation |
Score |
2024 |
Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, et al. Author Correction: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. PMID 38336833 DOI: 10.1038/s41586-024-07164-y |
0.376 |
|
2023 |
Kureshi R, Bello E, Kureshi CTS, Walsh MJ, Lippert V, Hoffman MT, Dougan M, Longmire T, Wichroski M, Dougan SK. DGKα/ζ inhibition lowers the TCR affinity threshold and potentiates antitumor immunity. Science Advances. 9: eadk1853. PMID 38000024 DOI: 10.1126/sciadv.adk1853 |
0.412 |
|
2023 |
Kurmi K, Liang D, van de Ven R, Georgiev P, Gassaway BM, Han S, Notarangelo G, Harris IS, Yao CH, Park JS, Hu SH, Peng J, Drijvers JM, Boswell S, Sokolov A, ... Dougan SK, et al. Metabolic modulation of mitochondrial mass during CD4 T cell activation. Cell Chemical Biology. PMID 37716347 DOI: 10.1016/j.chembiol.2023.08.008 |
0.312 |
|
2023 |
Ventre KS, Roehle K, Bello E, Bhuiyan AM, Biary T, Crowley SJ, Bruck PT, Heckler M, Lenehan PJ, Ali LR, Stump CT, Lippert V, Clancy-Thompson E, Conce Alberto WD, Hoffman MT, ... ... Dougan SK, et al. cIAP1/2 Antagonism Induces Antigen-Specific T Cell-Dependent Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 36881882 DOI: 10.4049/jimmunol.2200646 |
0.416 |
|
2022 |
Quijano-Rubio A, Bhuiyan AM, Yang H, Leung I, Bello E, Ali LR, Zhangxu K, Perkins J, Chun JH, Wang W, Lajoie MJ, Ravichandran R, Kuo YH, Dougan SK, Riddell SR, et al. A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy. Nature Biotechnology. PMID 36316485 DOI: 10.1038/s41587-022-01510-z |
0.321 |
|
2021 |
Stump CT, Roehle K, Manjarrez Orduno N, Dougan SK. Radiation combines with immune checkpoint blockade to enhance T cell priming in a murine model of poorly immunogenic pancreatic cancer. Open Biology. 11: 210245. PMID 34784792 DOI: 10.1098/rsob.210245 |
0.311 |
|
2021 |
Roehle K, Qiang L, Ventre KS, Heid D, Ali LR, Lenehan P, Heckler M, Crowley SJ, Stump CT, Ro G, Godicelj A, Bhuiyan AM, Yang A, Quiles Del Rey M, Biary T, ... ... Dougan SK, et al. cIAP1/2 antagonism eliminates MHC class I-negative tumors through T cell-dependent reprogramming of mononuclear phagocytes. Science Translational Medicine. 13. PMID 34011631 DOI: 10.1126/scitranslmed.abf5058 |
0.355 |
|
2021 |
Heckler M, Ali LR, Clancy-Thompson E, Qiang L, Ventre KS, Lenehan P, Roehle K, Luoma A, Boelaars K, Peters V, McCreary J, Boschert T, Wang ES, Suo S, Marangoni F, ... ... Dougan SK, et al. Inhibition of CDK4/6 promotes CD8 T-cell memory formation. Cancer Discovery. PMID 33941591 DOI: 10.1158/2159-8290.CD-20-1540 |
0.339 |
|
2020 |
Luoma AM, Suo S, Williams HL, Sharova T, Sullivan K, Manos M, Bowling P, Hodi FS, Rahma O, Sullivan RJ, Boland GM, Nowak JA, Dougan SK, Dougan M, Yuan GC, et al. Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy. Cell. PMID 32603654 DOI: 10.1016/J.Cell.2020.06.001 |
0.474 |
|
2020 |
Crowley SJ, Bruck PT, Bhuiyan MA, Mitchell-Gears A, Walsh MJ, Zhangxu K, Ali LR, Jeong HJ, Ingram JR, Knipe DM, Ploegh HL, Dougan M, Dougan SK. Neoleukin-2 enhances anti-tumour immunity downstream of peptide vaccination targeted by an anti-MHC class II VHH. Open Biology. 10: 190235. PMID 32019478 DOI: 10.1098/Rsob.190235 |
0.399 |
|
2019 |
Dougan SK, Dougan M. SMAC mimetics throw a molecular switch to control T17 responses. Science Signaling. 12. PMID 31455724 DOI: 10.1126/Scisignal.Aay3986 |
0.404 |
|
2019 |
Clancy-Thompson E, Chen GZ, LaMarche NM, Ali LR, Jeong HJ, Crowley SJ, Boelaars K, Brenner MB, Lynch L, Dougan SK. Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1. The Embo Journal. 38: e101260. PMID 31304630 DOI: 10.15252/Embj.2018101260 |
0.409 |
|
2019 |
Dougan M, Dougan SK. Programmable bacteria as cancer therapy. Nature Medicine. PMID 31270505 DOI: 10.1038/S41591-019-0513-4 |
0.333 |
|
2019 |
Clancy-Thompson E, Chen GZ, LaMarche NM, Ali LR, Jeong HJ, Crowley SJ, Boelaars K, Brenner MB, Lynch L, Dougan SK. Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1. The Embo Journal. PMID 31152007 DOI: 10.15252/embj.2018101260 |
0.301 |
|
2019 |
Balachandran VP, Beatty GL, Dougan SK. Broadening the impact of immunotherapy to pancreatic cancer: Challenges and opportunities. Gastroenterology. PMID 30660727 DOI: 10.1053/J.Gastro.2018.12.038 |
0.303 |
|
2019 |
Dougan SK. Abstract I09: Tumor-specific T cells reprogram mononuclear phagocytes for destruction of checkpoint blockade-resistant pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-I09 |
0.478 |
|
2019 |
Sheahan A, Morel K, Burkhart D, Baca S, Labbè D, Roehle K, Calagua C, Ye H, Galbo P, Panja S, Mitrofanova A, Hamid A, Kibel A, Choudhury A, Pomerantz M, ... ... Dougan S, et al. Abstract B006: Targeting EZH2 increases therapeutic efficacy of PD-1 blockade in models of prostate cancer Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-B006 |
0.332 |
|
2018 |
Clancy-Thompson E, Devlin CA, Tyler PM, Servos MM, Ali LR, Ventre KS, Bhuiyan MA, Bruck PT, Birnbaum M, Dougan SK. Altered binding of tumor antigenic peptides to MHC class I affects CD8 T cell effector responses. Cancer Immunology Research. PMID 30352798 DOI: 10.2210/Pdb6Mp0/Pdb |
0.468 |
|
2018 |
Yasmin-Karim S, Bruck PT, Moreau M, Kunjachan S, Chen GZ, Kumar R, Grabow S, Dougan SK, Ngwa W. Radiation and Local Anti-CD40 Generate an Effective Vaccine in Preclinical Models of Pancreatic Cancer. Frontiers in Immunology. 9: 2030. PMID 30245691 DOI: 10.3389/Fimmu.2018.02030 |
0.412 |
|
2018 |
Ito Y, Ashenberg O, Pyrdol J, Luoma AM, Rozenblatt-Rosen O, Hofree M, Christian E, Ferrari de Andrade L, Tay RE, Teyton L, Regev A, Dougan SK, Wucherpfennig KW. Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity. The Journal of Experimental Medicine. PMID 30185635 DOI: 10.1084/Jem.20180300 |
0.328 |
|
2018 |
Lin YC, Pecetta S, Steichen JM, Kratochvil S, Melzi E, Arnold J, Dougan SK, Wu L, Kirsch KH, Nair U, Schief WR, Batista FD. One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice. The Embo Journal. PMID 30087111 DOI: 10.15252/Embj.201899243 |
0.329 |
|
2018 |
Heckler M, Dougan SK. Unmasking Pancreatic Cancer: Epitope Spreading After Single Antigen Chimeric Antigen Receptor T-Cell Therapy in a Human Phase I Trial. Gastroenterology. PMID 29885301 DOI: 10.1053/J.Gastro.2018.06.023 |
0.393 |
|
2018 |
Dougan SK, Dougan M. Regulation of innate and adaptive antitumor immunity by IAP antagonists. Immunotherapy. PMID 29807457 DOI: 10.2217/Imt-2017-0185 |
0.436 |
|
2018 |
Krall JA, Reinhardt F, Mercury OA, Pattabiraman DR, Brooks MW, Dougan M, Lambert AW, Bierie B, Ploegh HL, Dougan SK, Weinberg RA. The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy. Science Translational Medicine. 10. PMID 29643230 DOI: 10.1126/Scitranslmed.Aan3464 |
0.305 |
|
2018 |
Ingram JR, Blomberg OS, Rashidian M, Ali L, Garforth S, Fedorov E, Fedorov AA, Bonanno JB, Le Gall C, Crowley S, Espinosa C, Biary T, Keliher EJ, Weissleder R, Almo SC, ... Dougan SK, et al. Anti-CTLA-4 therapy requires an Fc domain for efficacy. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581255 DOI: 10.1073/Pnas.1801524115 |
0.331 |
|
2018 |
Dougan M, Ingram JR, Jeong HJ, Mosaheb MM, Bruck PT, Ali L, Pishesha N, Blomberg O, Tyler PM, Servos MM, Rashidian M, Nguyen QD, von Andrian UH, Ploegh HL, Dougan SK. Targeting cytokine therapy to the pancreatic tumor microenvironment using PD-L1 specific VHHs. Cancer Immunology Research. PMID 29459478 DOI: 10.1158/2326-6066.Cir-17-0495 |
0.341 |
|
2017 |
Jeong HJ, Abhiraman GC, Story CM, Ingram JR, Dougan SK. Generation of Ca2+-independent sortase A mutants with enhanced activity for protein and cell surface labeling. Plos One. 12: e0189068. PMID 29200433 DOI: 10.1371/Journal.Pone.0189068 |
0.319 |
|
2017 |
Dougan SK. The Pancreatic Cancer Microenvironment. Cancer Journal (Sudbury, Mass.). 23: 321-325. PMID 29189327 DOI: 10.1097/Ppo.0000000000000288 |
0.381 |
|
2017 |
Clancy-Thompson E, Ali L, Bruck PT, Exley MA, Blumberg RS, Dranoff G, Dougan M, Dougan SK. IAP Antagonists Enhance Cytokine Production from Mouse and Human iNKT Cells. Cancer Immunology Research. PMID 29187357 DOI: 10.1158/2326-6066.Cir-17-0490 |
0.576 |
|
2017 |
Zeissig S, Peuker K, Iyer S, Gensollen T, Dougan SK, Olszak T, Kaser A, Blumberg RS. CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28893990 DOI: 10.1073/Pnas.1701428114 |
0.594 |
|
2017 |
Ingram JR, Blomberg OS, Sockolosky JT, Ali L, Schmidt FI, Pishesha N, Espinosa C, Dougan SK, Garcia KC, Ploegh HL, Dougan M. Localized CD47 blockade enhances immunotherapy for murine melanoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 28874561 DOI: 10.1073/Pnas.1710776114 |
0.383 |
|
2017 |
Clancy-Thompson E, Chen GZ, Tyler PM, Servos MM, Barisa M, Brennan PJ, Ploegh HL, Dougan SK. Monoclonal Invariant NKT (iNKT) Cell Mice Reveal a Role for Both Tissue of Origin and the TCR in Development of iNKT Functional Subsets. Journal of Immunology (Baltimore, Md. : 1950). PMID 28576977 DOI: 10.4049/Jimmunol.1700214 |
0.38 |
|
2017 |
Dougan M, Dougan SK. Targeting Immunotherapy to the Tumor Microenvironment. Journal of Cellular Biochemistry. PMID 28332219 DOI: 10.1002/Jcb.26005 |
0.305 |
|
2017 |
Pishesha N, Bilate AM, Wibowo MC, Huang NJ, Li Z, Dhesycka R, Bousbaine D, Li H, Patterson HC, Dougan SK, Maruyama T, Lodish HF, Ploegh HL. Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 28270614 DOI: 10.1073/Pnas.1701746114 |
0.442 |
|
2017 |
Tyler PM, Servos MM, de Vries RC, Klebanov B, Kashyap T, Sacham S, Landesman Y, Dougan M, Dougan SK. Clinical dosing regimen of selinexor maintains normal immune homeostasis and T cell effector function in mice: implications for combination with immunotherapy. Molecular Cancer Therapeutics. PMID 28148714 DOI: 10.1182/Blood.V128.22.2525.2525 |
0.482 |
|
2017 |
Sanderson NS, Zimmermann M, Eilinger L, Gubser C, Schaeren-Wiemers N, Lindberg RL, Dougan SK, Ploegh HL, Kappos L, Derfuss T. Cocapture of cognate and bystander antigens can activate autoreactive B cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28057865 DOI: 10.1073/Pnas.1614472114 |
0.454 |
|
2016 |
Bilate AM, Bousbaine D, Mesin L, Agudelo M, Leube J, Kratzert A, Dougan SK, Victora GD, Ploegh HL. Tissue-specific emergence of regulatory and intraepithelial T cells from a clonal T cell precursor. Science Immunology. 1: eaaf7471. PMID 28783695 DOI: 10.1126/Sciimmunol.Aaf7471 |
0.484 |
|
2016 |
Sanecka A, Yoshida N, Dougan SK, Jackson J, Shastri N, Ploegh H, Blanchard N, Frickel EM. Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute phase Toxoplasma gondii burden. Immunology. PMID 27377596 DOI: 10.1111/Imm.12643 |
0.453 |
|
2016 |
Dura B, Servos MM, Barry RM, Ploegh HL, Dougan SK, Voldman J. Longitudinal multiparameter assay of lymphocyte interactions from onset by microfluidic cell pairing and culture. Proceedings of the National Academy of Sciences of the United States of America. PMID 27303033 DOI: 10.1073/Pnas.1515364113 |
0.38 |
|
2016 |
Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, et al. Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. PMID 26982724 DOI: 10.1038/Nature17421 |
0.434 |
|
2016 |
Tyler P, Servos M, Dougan SK. Abstract A067: Quality of initial activation of CD8 T cells specific for TRP1 determines long-term antitumor immunity Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A067 |
0.473 |
|
2016 |
Dougan M, Ingram J, Ploegh H, Dougan SK. Abstract B112: Targeting immunotherapy to the tumor microenvironment using anti-PDL1 VHH Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B112 |
0.374 |
|
2015 |
Tafesse FG, Rashidfarrokhi A, Schmidt FI, Freinkman E, Dougan S, Dougan M, Esteban A, Maruyama T, Strijbis K, Ploegh HL. Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans. Plos Pathogens. 11: e1005188. PMID 26431038 DOI: 10.1371/Journal.Ppat.1005188 |
0.399 |
|
2015 |
Santone M, Aprea S, Wu TY, Cooke MP, Mbow ML, Valiante NM, Rush JS, Dougan S, Avalos A, Ploegh H, De Gregorio E, Buonsanti C, D'Oro U. A new TLR2 agonist promotes cross-presentation by mouse and human antigen presenting cells. Human Vaccines & Immunotherapeutics. 0. PMID 26024409 DOI: 10.1080/21645515.2015.1027467 |
0.465 |
|
2015 |
Dura B, Dougan SK, Barisa M, Hoehl MM, Lo CT, Ploegh HL, Voldman J. Profiling lymphocyte interactions at the single-cell level by microfluidic cell pairing. Nature Communications. 6: 5940. PMID 25585172 DOI: 10.1038/Ncomms6940 |
0.416 |
|
2015 |
Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, et al. CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. 517: 386-90. PMID 25363763 DOI: 10.1038/Nature13848 |
0.606 |
|
2015 |
Dougan SK, Bilate A, Jaenisch R, Ploegh HL. Abstract B59: Transnuclear mice as models of the immune response to pancreatic cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B59 |
0.477 |
|
2014 |
Zeissig S, Petersen BS, Tomczak M, Melum E, Huc-Claustre E, Dougan SK, Laerdahl JK, Stade B, Forster M, Schreiber S, Weir D, Leichtner AM, Franke A, Blumberg RS. Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4. Gut. PMID 25367873 DOI: 10.1136/Gutjnl-2014-308541 |
0.431 |
|
2014 |
Shi J, Kundrat L, Pishesha N, Bilate A, Theile C, Maruyama T, Dougan SK, Ploegh HL, Lodish HF. Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes. Proceedings of the National Academy of Sciences of the United States of America. 111: 10131-6. PMID 24982154 DOI: 10.1073/Pnas.1409861111 |
0.336 |
|
2014 |
Zhou P, Shaffer DR, Alvarez Arias DA, Nakazaki Y, Pos W, Torres AJ, Cremasco V, Dougan SK, Cowley GS, Elpek K, Brogdon J, Lamb J, Turley SJ, Ploegh HL, Root DE, et al. In vivo discovery of immunotherapy targets in the tumour microenvironment. Nature. 506: 52-7. PMID 24476824 DOI: 10.1038/Nature12988 |
0.452 |
|
2013 |
Dougan SK, Dougan M, Kim J, Turner JA, Ogata S, Cho HI, Jaenisch R, Celis E, Ploegh HL. Transnuclear TRP1-specific CD8 T cells with high or low affinity TCRs show equivalent antitumor activity. Cancer Immunology Research. 1: 99-111. PMID 24459675 DOI: 10.1158/2326-6066.Cir-13-0047 |
0.491 |
|
2013 |
Dougan SK, Ashour J, Karssemeijer RA, Popp MW, Avalos AM, Barisa M, Altenburg AF, Ingram JR, Cragnolini JJ, Guo C, Alt FW, Jaenisch R, Ploegh HL. Antigen-specific B-cell receptor sensitizes B cells to infection by influenza virus. Nature. 503: 406-9. PMID 24141948 DOI: 10.1038/Nature12637 |
0.345 |
|
2013 |
Fang M, Xie H, Dougan SK, Ploegh H, van Oudenaarden A. Stochastic cytokine expression induces mixed T helper cell States. Plos Biology. 11: e1001618. PMID 23935453 DOI: 10.1371/Journal.Pbio.1001618 |
0.416 |
|
2013 |
Strijbis K, Tafesse FG, Fairn GD, Witte MD, Dougan SK, Watson N, Spooner E, Esteban A, Vyas VK, Fink GR, Grinstein S, Ploegh HL. Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages. Plos Pathogens. 9: e1003446. PMID 23825946 DOI: 10.1371/Journal.Ppat.1003446 |
0.322 |
|
2012 |
Dougan SK, Ogata S, Hu CC, Grotenbreg GM, Guillen E, Jaenisch R, Ploegh HL. IgG1+ ovalbumin-specific B-cell transnuclear mice show class switch recombination in rare allelically included B cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 13739-44. PMID 22869725 DOI: 10.1073/Pnas.1210273109 |
0.38 |
|
2012 |
Dougan SK, Bilate A, Ploegh H. Abstract B75: Transnuclear mice from pancreatic tumor-infiltrating T cells. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B75 |
0.474 |
|
2011 |
Dougan SK, Hu CC, Paquet ME, Greenblatt MB, Kim J, Lilley BN, Watson N, Ploegh HL. Derlin-2-deficient mice reveal an essential role for protein dislocation in chondrocytes. Molecular and Cellular Biology. 31: 1145-59. PMID 21220515 DOI: 10.1128/Mcb.00967-10 |
0.368 |
|
2011 |
Zeissig S, Murata K, Hu Z, Kaser A, Dougan S, Bosse E, Scapa E, Cohen D, Arlt A, Franke A, Schreiber S, Liang T, Blumberg R. Hepatitis B-Virus-induzierte hepatozytäre Lipidantigene aktivieren Natürliche Killer T-Zellen und sind von zentraler Bedeutung für die antivirale Immunantwort Zeitschrift FüR Gastroenterologie. 49. DOI: 10.1055/S-0031-1285206 |
0.486 |
|
2011 |
Zeissig S, Murata K, Hu Z, Kaser A, Dougan SK, Bosse E, Scapa EF, Cohen DE, Arlt A, Franke A, Schreiber S, Liang TJ, Blumberg RS. Early Alterations in Endogenous Hepatocyte Lipid Antigens in Hepatitis B Virus Infection Are Associated With CD1D-Restricted Natural Killer T Cell Activation and Viral Clearance Gastroenterology. 140: S-886. DOI: 10.1016/S0016-5085(11)63685-8 |
0.541 |
|
2010 |
Dougan M, Dougan S, Slisz J, Firestone B, Vanneman M, Draganov D, Goyal G, Li W, Neuberg D, Blumberg R, Hacohen N, Porter D, Zawel L, Dranoff G. IAP inhibitors enhance co-stimulation to promote tumor immunity. The Journal of Experimental Medicine. 207: 2195-206. PMID 20837698 DOI: 10.1084/Jem.20101123 |
0.575 |
|
2010 |
Zeissig S, Dougan SK, Barral DC, Junker Y, Chen Z, Kaser A, Ho M, Mandel H, McIntyre A, Kennedy SM, Painter GF, Veerapen N, Besra GS, Cerundolo V, Yue S, et al. Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function. The Journal of Clinical Investigation. 120: 2889-99. PMID 20592474 DOI: 10.1172/Jci42703 |
0.564 |
|
2009 |
Hu CC, Dougan SK, Winter SV, Paton AW, Paton JC, Ploegh HL. Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes. The Journal of Experimental Medicine. 206: 2429-40. PMID 19808260 DOI: 10.1084/Jem.20090782 |
0.369 |
|
2009 |
McGehee AM, Dougan SK, Klemm EJ, Shui G, Park B, Kim YM, Watson N, Wenk MR, Ploegh HL, Hu CC. XBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis. Journal of Immunology (Baltimore, Md. : 1950). 183: 3690-9. PMID 19710472 DOI: 10.4049/Jimmunol.0900953 |
0.387 |
|
2009 |
Hu CC, Dougan SK, McGehee AM, Love JC, Ploegh HL. XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells. The Embo Journal. 28: 1624-36. PMID 19407814 DOI: 10.1038/Emboj.2009.117 |
0.4 |
|
2009 |
Zeissig S, Kaser A, Dougan SK, Scapa EF, Cohen DE, Blumberg RS. T1701 Microsomal Triglyceride Transfer Protein Regulates CD1D-Restricted Antigen Presentation of Hepatocytes and Controls NKT Cell Homeostasis via CD1D-Mediated Apoptosis Gastroenterology. 136: A-561. DOI: 10.1016/S0016-5085(09)62582-8 |
0.54 |
|
2009 |
Zeissig S, Dougan SK, Junker Y, Chen Z, Chen X, Kennedy S, Ho MM, Mandel H, Yue SC, Gumperz JE, Exley MA, Davidson NO, Blumberg RS. 706 Mutations in the Microsomal Triglyceride Transfer Protein Lead to a Defect in CD1D-Restricted Antigen Presentation and Impaired Activation of Natural Killer T Cells in Patients with Abetalipoproteinemia Gastroenterology. 136: A-111. DOI: 10.1016/S0016-5085(09)60501-1 |
0.554 |
|
2008 |
Kaser A, Hava DL, Dougan SK, Chen Z, Zeissig S, Brenner MB, Blumberg RS. Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules. European Journal of Immunology. 38: 2351-9. PMID 18624350 DOI: 10.1002/Eji.200738102 |
0.591 |
|
2008 |
Hussain MM, Rava P, Pan X, Dai K, Dougan SK, Iqbal J, Lazare F, Khatun I. Microsomal triglyceride transfer protein in plasma and cellular lipid metabolism. Current Opinion in Lipidology. 19: 277-84. PMID 18460919 DOI: 10.1097/Mol.0B013E3282Feea85 |
0.31 |
|
2008 |
Zeissig S, Kaser A, Dougan S, Blumberg R. Das Microsomale Triglyzerid-Transferprotein (MTP) beeinflusst die CD1d-vermittelte Antigen-Präsentation von Hepatozyten und reguliert die periphere Natural Killer T (NKT)-Zell Homöostase Zeitschrift FüR Gastroenterologie. 46. DOI: 10.1055/S-0028-1089464 |
0.528 |
|
2008 |
Zeissig S, Kaser A, Dougan SK, Blumberg RS. T1241 Microsomal Triglyceride Transfer Protein Regulates CD1d-Restricted Antigen Presentation of Hepatocytes and Controls Natural Killer T Cell Homeostasis Via CD1d-Mediated Apoptosis Gastroenterology. 134: A-514. DOI: 10.1016/S0016-5085(08)62398-7 |
0.585 |
|
2007 |
Zeissig S, Kaser A, Dougan SK, Nieuwenhuis EE, Blumberg RS. Role of NKT cells in the digestive system. III. Role of NKT cells in intestinal immunity. American Journal of Physiology. Gastrointestinal and Liver Physiology. 293: G1101-5. PMID 17717040 DOI: 10.1152/Ajpgi.00342.2007 |
0.587 |
|
2007 |
Dougan SK, Kaser A, Blumberg RS. CD1 expression on antigen-presenting cells. Current Topics in Microbiology and Immunology. 314: 113-41. PMID 17593659 DOI: 10.1007/978-3-540-69511-0_5 |
0.54 |
|
2007 |
Dougan SK, Rava P, Hussain MM, Blumberg RS. MTP regulated by an alternate promoter is essential for NKT cell development. The Journal of Experimental Medicine. 204: 533-45. PMID 17312007 DOI: 10.1084/Jem.20062006 |
0.599 |
|
2005 |
Dougan SK, Salas A, Rava P, Agyemang A, Kaser A, Morrison J, Khurana A, Kronenberg M, Johnson C, Exley M, Hussain MM, Blumberg RS. Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells. The Journal of Experimental Medicine. 202: 529-39. PMID 16087713 DOI: 10.1084/Jem.20050183 |
0.56 |
|
Low-probability matches (unlikely to be authored by this person) |
2017 |
Yasmin-Karim S, Moreau M, Kumar R, Dougan S, Ngwa W. Enhancement of the Abscopal Effect in Radiation Therapy by In Situ Delivered CD40 Antibody in Pancreatic Adenocarcinoma International Journal of Radiation Oncology Biology Physics. 99. DOI: 10.1016/J.Ijrobp.2017.06.2120 |
0.286 |
|
2017 |
Ngwa W, Dougan S, Kumar R. Combining Nanoparticle-Aided Radiation Therapy with Immunotherapy to Enhance Local and Metastatic Tumor Cell Kill During Pancreatic Cancer Treatment International Journal of Radiation Oncology Biology Physics. 99. DOI: 10.1016/J.Ijrobp.2017.06.2073 |
0.285 |
|
2022 |
Dobson CS, Reich AN, Gaglione S, Smith BE, Kim EJ, Dong J, Ronsard L, Okonkwo V, Lingwood D, Dougan M, Dougan SK, Birnbaum ME. Antigen identification and high-throughput interaction mapping by reprogramming viral entry. Nature Methods. 19: 449-460. PMID 35396484 DOI: 10.1038/s41592-022-01436-z |
0.28 |
|
2011 |
Popp MW, Dougan SK, Chuang TY, Spooner E, Ploegh HL. Sortase-catalyzed transformations that improve the properties of cytokines. Proceedings of the National Academy of Sciences of the United States of America. 108: 3169-74. PMID 21297034 DOI: 10.1073/Pnas.1016863108 |
0.28 |
|
2014 |
Strijbis K, Yilmaz OH, Dougan SK, Esteban A, Gröne A, Kumamoto CA, Ploegh HL. Intestinal colonization by Candida albicans alters inflammatory responses in Bruton's tyrosine kinase-deficient mice. Plos One. 9: e112472. PMID 25379804 DOI: 10.1371/Journal.Pone.0112472 |
0.274 |
|
2023 |
Ali LR, Lenehan PJ, Cardot-Ruffino V, Dias Costa A, Katz MHG, Bauer TW, Nowak JA, Wolpin BM, Abrams TA, Patel A, Clancy TE, Wang J, Mancias JD, Reilley MJ, Stucky CH, ... ... Dougan SK, et al. PD-1 blockade induces reactivation of non-productive T cell responses characterized by NF-kB signaling in patients with pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37733830 DOI: 10.1158/1078-0432.CCR-23-1444 |
0.273 |
|
2023 |
Walsh MJ, Stump CT, Kureshi R, Lenehan P, Ali LR, Dougan M, Knipe DM, Dougan SK. IFNγ is a central node of cancer immune equilibrium. Cell Reports. 42: 112219. PMID 36881506 DOI: 10.1016/j.celrep.2023.112219 |
0.269 |
|
2017 |
Ingram JR, Dougan M, Rashidian M, Knoll M, Keliher EJ, Garrett S, Garforth S, Blomberg OS, Espinosa C, Bhan A, Almo SC, Weissleder R, Lodish H, Dougan SK, Ploegh HL. PD-L1 is an activation-independent marker of brown adipocytes. Nature Communications. 8: 647. PMID 28935898 DOI: 10.1038/S41467-017-00799-8 |
0.266 |
|
2022 |
Johnson S, Haigis MC, Dougan SK. Dangerous dynamic duo: Lactic acid and PD-1 blockade. Cancer Cell. PMID 35093211 DOI: 10.1016/j.ccell.2022.01.008 |
0.264 |
|
2015 |
Maruyama T, Dougan SK, Truttmann MC, Bilate AM, Ingram JR, Ploegh HL. Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining. Nature Biotechnology. 33: 538-42. PMID 25798939 DOI: 10.1038/Nbt.3190 |
0.261 |
|
2012 |
Hess GT, Cragnolini JJ, Popp MW, Allen MA, Dougan SK, Spooner E, Ploegh HL, Belcher AM, Guimaraes CP. M13 bacteriophage display framework that allows sortase-mediated modification of surface-accessible phage proteins. Bioconjugate Chemistry. 23: 1478-87. PMID 22759232 DOI: 10.1021/Bc300130Z |
0.26 |
|
2023 |
Ali LR, Garrido-Castro AC, Lenehan PJ, Bollenrucher N, Stump CT, Dougan M, Goel S, Shapiro GI, Tolaney SM, Dougan SK. PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of Experimental Medicine. 220. PMID 36688919 DOI: 10.1084/jem.20220729 |
0.26 |
|
2011 |
Hoehl MM, Dougan SK, Ploegh HL, Voldman J. Massively parallel microfluidic cell-pairing platform for the statistical study of immunological cell-cell interactions 15th International Conference On Miniaturized Systems For Chemistry and Life Sciences 2011, Microtas 2011. 3: 1508-1510. |
0.248 |
|
2012 |
Witte MD, Cragnolini JJ, Dougan SK, Yoder NC, Popp MW, Ploegh HL. Preparation of unnatural N-to-N and C-to-C protein fusions. Proceedings of the National Academy of Sciences of the United States of America. 109: 11993-8. PMID 22778432 DOI: 10.1073/Pnas.1205427109 |
0.244 |
|
2019 |
Dougan M, Dranoff G, Dougan SK. GM-CSF, IL-3, and IL-5 Family of Cytokines: Regulators of Inflammation. Immunity. 50: 796-811. PMID 30995500 DOI: 10.1016/J.Immuni.2019.03.022 |
0.243 |
|
2023 |
Qiang L, Hoffman MT, Ali LR, Castillo JI, Kageler L, Temesgen A, Lenehan P, Wang SJ, Bello E, Cardot-Ruffino V, Uribe GA, Yang A, Dougan M, Aguirre AJ, Raghavan S, ... ... Dougan SK, et al. TGFβ blockade in pancreatic cancer enhances sensitivity to combination chemotherapy. Gastroenterology. PMID 37263309 DOI: 10.1053/j.gastro.2023.05.038 |
0.231 |
|
2023 |
Ali LR, Garrido-Castro AC, Lenehan PJ, Bollenrucher N, Stump CT, Dougan M, Goel S, Shapiro GI, Tolaney SM, Dougan SK. Correction: PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of Experimental Medicine. 220. PMID 37615687 DOI: 10.1084/jem.2022072908182023c |
0.22 |
|
2020 |
Dougan SK. TGFβ: Protecting PD-1 from mRNA Decay. Cancer Immunology Research. 8: 1464. PMID 33262162 DOI: 10.1158/2326-6066.CIR-20-0881 |
0.214 |
|
2021 |
Dougan M, Luoma AM, Dougan SK, Wucherpfennig KW. Understanding and treating the inflammatory adverse events of cancer immunotherapy. Cell. 184: 1575-1588. PMID 33675691 DOI: 10.1016/j.cell.2021.02.011 |
0.212 |
|
2021 |
Morel KL, Sheahan AV, Burkhart DL, Baca SC, Boufaied N, Liu Y, Qiu X, Cañadas I, Roehle K, Heckler M, Calagua C, Ye H, Pantelidou C, Galbo P, Panja S, ... ... Dougan SK, et al. EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer. Nature Cancer. 2: 444-456. PMID 33899001 DOI: 10.1038/s43018-021-00185-w |
0.209 |
|
2018 |
Dougan M, Dranoff G, Dougan SK. Cancer Immunotherapy: Beyond Checkpoint Blockade. Annual Review of Cancer Biology. 3: 55-75. PMID 37539076 DOI: 10.1146/annurev-cancerbio-030518-055552 |
0.208 |
|
2024 |
Aney KJ, Jeong WJ, Vallejo AF, Burdziak C, Chen E, Wang A, Koak P, Wise K, Jensen K, Pe'er D, Dougan SK, Martelotto L, Nissim S. A Novel Approach for Pancreas Transcriptomics Reveals the Cellular Landscape in Homeostasis and Acute Pancreatitis. Gastroenterology. PMID 38325760 DOI: 10.1053/j.gastro.2024.01.043 |
0.203 |
|
2023 |
Cardot-Ruffino V, Bollenrucher N, Delius L, Wang SJ, Brais LK, Remland J, Keheler CE, Sullivan KM, Abrams TA, Biller LH, Enzinger PC, McCleary NJ, Patel AK, Rubinson DA, Schlechter B, ... ... Dougan SK, et al. G-CSF rescue of FOLFIRINOX-induced neutropenia leads to systemic immune suppression in mice and humans. Journal For Immunotherapy of Cancer. 11. PMID 37344102 DOI: 10.1136/jitc-2022-006589 |
0.2 |
|
2023 |
Walsh MJ, Ali LR, Lenehan P, Kureshi CT, Kureshi R, Dougan M, Knipe DM, Dougan SK. Blockade of innate inflammatory cytokines TNF, IL-1, or IL-6 overcomes virotherapy-induced cancer equilibrium to promote tumor regression. Immunotherapy Advances. 3: ltad011. PMID 37461742 DOI: 10.1093/immadv/ltad011 |
0.196 |
|
2022 |
Dias Costa A, Väyrynen SA, Chawla A, Zhang J, Väyrynen JP, Lau MC, Williams HL, Yuan C, Morales-Oyarvide V, Elganainy D, Singh H, Cleary JM, Perez K, Ng K, Freed-Pastor W, ... ... Dougan SK, et al. Neoadjuvant chemotherapy is associated with altered immune cell infiltration and an anti-tumorigenic microenvironment in resected pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 36129461 DOI: 10.1158/1078-0432.CCR-22-1125 |
0.196 |
|
2023 |
Wang SJ, Dougan SK, Dougan M. Immune mechanisms of toxicity from checkpoint inhibitors. Trends in Cancer. PMID 37117135 DOI: 10.1016/j.trecan.2023.04.002 |
0.194 |
|
2016 |
Maruyama T, Dougan SK, Truttmann MC, Bilate AM, Ingram JR, Ploegh HL. Corrigendum: Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining. Nature Biotechnology. 34: 210. PMID 26849523 DOI: 10.1038/Nbt0216-210C |
0.191 |
|
2023 |
Lee MS, Dennis C, Naqvi I, Dailey L, Lorzadeh A, Ye G, Zaytouni T, Adler A, Hitchcock DS, Lin L, Hoffman MT, Bhuiyan AM, Barth JL, Machacek ME, Mino-Kenudson M, ... Dougan SK, et al. Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer. Nature. PMID 36991126 DOI: 10.1038/s41586-023-05891-2 |
0.176 |
|
2004 |
Chan WH, Zerizer I, Shergill N, Shergill I, Dougan S. A rare cause of abdominal pain. Gut. 53: 1261, 1266. PMID 15306581 DOI: 10.1136/Gut.2003.033589 |
0.176 |
|
2021 |
Wechsler ME, Munitz A, Ackerman SJ, Drake MG, Jackson DJ, Wardlaw AJ, Dougan SK, Berdnikovs S, Schleich F, Matucci A, Chanez P, Prazma CM, Howarth P, Weller PF, Merkel PA. Eosinophils in Health and Disease: A State-of-the-Art Review. Mayo Clinic Proceedings. PMID 34538424 DOI: 10.1016/j.mayocp.2021.04.025 |
0.176 |
|
2023 |
Liu SY, Mulugeta N, Dougan SK, Qiang L. In vitro flow cytometry assay to assess primary human and mouse macrophage phagocytosis of live cells. Star Protocols. 4: 102240. PMID 37074910 DOI: 10.1016/j.xpro.2023.102240 |
0.175 |
|
2023 |
Katz MHG, Petroni GR, Bauer T, Reilley MJ, Wolpin BM, Stucky CC, Bekaii-Saab TS, Elias R, Merchant N, Dias Costa A, Lenehan P, Cardot-Ruffino V, Rodig S, Pfaff K, Dougan SK, et al. Multicenter randomized controlled trial of neoadjuvant chemoradiotherapy alone or in combination with pembrolizumab in patients with resectable or borderline resectable pancreatic adenocarcinoma. Journal For Immunotherapy of Cancer. 11. PMID 38040420 DOI: 10.1136/jitc-2023-007586 |
0.161 |
|
2023 |
Bertocchi A, Dougan SK. IL-3 finds its home in the brain. Immunity. 56: 1431-1433. PMID 37437533 DOI: 10.1016/j.immuni.2023.06.009 |
0.147 |
|
2024 |
Huffman BM, Singh H, Ali LR, Horick N, Wang SJ, Hoffman MT, Metayer KA, Murray S, Bird A, Abrams TA, Biller LH, Chan JA, Meyerhardt JA, McCleary NJ, Goessling W, ... ... Dougan SK, et al. Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders. Journal For Immunotherapy of Cancer. 12. PMID 38272561 DOI: 10.1136/jitc-2023-008436 |
0.146 |
|
2022 |
Uchida AM, Ro G, Qiang L, Peterson KA, Round J, Dougan M, Dougan SK. Human differentiated eosinophils release IL-13 in response to IL-33 stimulation. Frontiers in Immunology. 13: 946643. PMID 36177009 DOI: 10.3389/fimmu.2022.946643 |
0.143 |
|
2021 |
Cleary JM, Wolpin BM, Dougan SK, Raghavan S, Singh H, Huffman B, Sethi NS, Nowak JA, Shapiro GI, Aguirre AJ, D'Andrea AD. Opportunities for Utilization of DNA Repair Inhibitors in Homologous Recombination Repair-Deficient and Proficient Pancreatic Adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34285063 DOI: 10.1158/1078-0432.CCR-21-1367 |
0.138 |
|
2021 |
Lenehan PJ, Cirella A, Uchida AM, Crowley SJ, Sharova T, Boland G, Dougan M, Dougan SK, Heckler M. Type 2 immunity is maintained during cancer-associated adipose tissue wasting. Immunotherapy Advances. 1: ltab011. PMID 34291232 DOI: 10.1093/immadv/ltab011 |
0.132 |
|
2022 |
Hosein AN, Dougan SK, Aguirre AJ, Maitra A. Translational advances in pancreatic ductal adenocarcinoma therapy. Nature Cancer. 3: 272-286. PMID 35352061 DOI: 10.1038/s43018-022-00349-2 |
0.108 |
|
2023 |
Hoffman MT, Dougan SK. Pancreatic Neoplasms Are Frighteningly Common: A Role for Immune Surveillance? Cancer Discovery. 13: 1288-1290. PMID 37264826 DOI: 10.1158/2159-8290.CD-23-0332 |
0.086 |
|
2021 |
Uchida AM, Lenehan PJ, Vimalathas P, Miller KC, Valencia-Yang M, Qiang L, Canha LA, Ali LR, Dougan M, Garber JJ, Dougan SK. Tissue eosinophils express the IL-33 receptor ST2 and type 2 cytokines in patients with eosinophilic esophagitis. Allergy. PMID 34614218 DOI: 10.1111/all.15127 |
0.083 |
|
2022 |
Qiang L, Dougan SK. Bicarbonate transport as a vulnerability in pancreatic cancer. Nature Cancer. PMID 36522549 DOI: 10.1038/s43018-022-00492-w |
0.065 |
|
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