Nicholas Schork - Publications

Affiliations: 
TSRI, San Diego, CA, United States 
Area:
statistical genetics of neuropschiatric disorders

287 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, ... ... Schork NJ, et al. Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics. PMID 31043756 DOI: 10.1038/s41588-019-0397-8  0.52
2018 Bakken TE, Hodge RD, Miller JA, Yao Z, Nguyen TN, Aevermann B, Barkan E, Bertagnolli D, Casper T, Dee N, Garren E, Goldy J, Graybuck LT, Kroll M, Lasken RS, ... ... Schork NJ, et al. Single-nucleus and single-cell transcriptomes compared in matched cortical cell types. Plos One. 13: e0209648. PMID 30586455 DOI: 10.1371/journal.pone.0209648  0.52
2018 Boldog E, Bakken TE, Hodge RD, Novotny M, Aevermann BD, Baka J, Bordé S, Close JL, Diez-Fuertes F, Ding SL, Faragó N, Kocsis ÁK, Kovács B, Maltzer Z, McCorrison JM, ... ... Schork NJ, et al. Transcriptomic and morphophysiological evidence for a specialized human cortical GABAergic cell type. Nature Neuroscience. PMID 30150662 DOI: 10.1038/s41593-018-0205-2  0.52
2017 Boeldt DL, Cheung C, Ariniello L, Darst BF, Topol S, Schork NJ, Philis-Tsimikas A, Torkamani A, Fortmann AL, Bloss CS. Patient perspectives on whole-genome sequencing for undiagnosed diseases. Personalized Medicine. 14: 17-25. PMID 29749824 DOI: 10.2217/pme-2016-0050  0.4
2017 Bakken T, Cowell L, Aevermann BD, Novotny M, Hodge R, Miller JA, Lee A, Chang I, McCorrison J, Pulendran B, Qian Y, Schork NJ, Lasken RS, Lein ES, Scheuermann RH. Cell type discovery and representation in the era of high-content single cell phenotyping. Bmc Bioinformatics. 18: 559. PMID 29322913 DOI: 10.1186/s12859-017-1977-1  0.52
2016 Peng Q, Schork A, Bartsch H, Lo MT, Panizzon MS, Westlye LT, Kremen WS, Jernigan TL, Le Hellard S, Steen VM, Espeseth T, Huentelman M, Håberg AK, ... ... Schork NJ, et al. Conservation of Distinct Genetically-Mediated Human Cortical Pattern. Plos Genetics. 12: e1006143. PMID 27459196 DOI: 10.1371/journal.pgen.1006143  0.52
2016 Bhutani K, Nazor KL, Williams R, Tran H, Dai H, Džakula Ž, Cho EH, Pang AW, Rao M, Cao H, Schork NJ, Loring JF. Whole-genome mutational burden analysis of three pluripotency induction methods. Nature Communications. 7: 10536. PMID 26892726 DOI: 10.1038/ncomms10536  0.52
2015 Libiger O, Schork NJ. Partial Least Squares Regression Can Aid in Detecting Differential Abundance of Multiple Features in Sets of Metagenomic Samples. Frontiers in Genetics. 6: 350. PMID 26734061 DOI: 10.3389/fgene.2015.00350  0.52
2015 Standish KA, Carland TM, Lockwood GK, Pfeiffer W, Tatineni M, Huang CC, Lamberth S, Cherkas Y, Brodmerkel C, Jaeger E, Smith L, Rajagopal G, Curran ME, Schork NJ. Group-based variant calling leveraging next-generation supercomputing for large-scale whole-genome sequencing studies. Bmc Bioinformatics. 16: 304. PMID 26395405 DOI: 10.1186/s12859-015-0736-4  0.52
2015 Chen CH, Peng Q, Schork AJ, Lo MT, Fan CC, Wang Y, Desikan RS, Bettella F, Hagler DJ, Westlye LT, Kremen WS, Jernigan TL, Hellard SL, ... ... Schork N, et al. Large-scale genomics unveil polygenic architecture of human cortical surface area. Nature Communications. 6: 7549. PMID 26189703 DOI: 10.1038/ncomms8549  0.52
2015 Newman E, Thompson WK, Bartsch H, Hagler DJ, Chen CH, Brown TT, Kuperman JM, McCabe C, Chung Y, Libiger O, Akshoomoff N, Bloss CS, Casey BJ, Chang L, Ernst TM, ... ... Schork N, et al. Anxiety is related to indices of cortical maturation in typically developing children and adolescents. Brain Structure & Function. PMID 26183468 DOI: 10.1007/s00429-015-1085-9  0.52
2015 Fan CC, Bartsch H, Schork AJ, Chen CH, Wang Y, Lo MT, Brown TT, Kuperman JM, Hagler DJ, Schork NJ, Jernigan TL, Dale AM. Modeling the 3D Geometry of the Cortical Surface with Genetic Ancestry. Current Biology : Cb. PMID 26166778 DOI: 10.1016/j.cub.2015.06.006  0.52
2015 Eicher JD, Montgomery AM, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork NJ, Darst BF, Casey BJ, Chang L, Ernst T, Frazier J, Kaufmann WE, Keating B, Kenet T, et al. Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children. Brain Imaging and Behavior. PMID 25953057 DOI: 10.1007/s11682-015-9392-6  0.52
2015 Jernigan TL, Brown TT, Hagler DJ, Akshoomoff N, Bartsch H, Newman E, Thompson WK, Bloss CS, Murray SS, Schork N, Kennedy DN, Kuperman JM, McCabe C, Chung Y, Libiger O, et al. The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository. Neuroimage. PMID 25937488 DOI: 10.1016/j.neuroimage.2015.04.057  0.52
2015 Yin X, Cheng H, Lin Y, Wineinger NE, Zhou F, Sheng Y, Yang C, Li P, Li F, Shen C, Yang S, Schork NJ, Zhang X. A weighted polygenic risk score using 14 known susceptibility variants to estimate risk and age onset of psoriasis in Han Chinese. Plos One. 10: e0125369. PMID 25933357 DOI: 10.1371/journal.pone.0125369  0.52
2015 Schork NJ. Personalized medicine: Time for one-person trials. Nature. 520: 609-11. PMID 25925459 DOI: 10.1038/520609a  0.52
2015 Shih PB, Yang J, Morisseau C, German JB, Zeeland AA, Armando AM, Quehenberger O, Bergen AW, Magistretti P, Berrettini W, Halmi KA, Schork N, Hammock BD, Kaye W. Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa. Molecular Psychiatry. PMID 25824304 DOI: 10.1038/mp.2015.26  0.52
2015 Noble KG, Houston SM, Brito NH, Bartsch H, Kan E, Kuperman JM, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork NJ, Murray SS, Casey BJ, Chang L, Ernst TM, et al. Family income, parental education and brain structure in children and adolescents. Nature Neuroscience. 18: 773-8. PMID 25821911 DOI: 10.1038/nn.3983  0.52
2015 Bloss CS, Zeeland AA, Topol SE, Darst BF, Boeldt DL, Erikson GA, Bethel KJ, Bjork RL, Friedman JR, Hwynn N, Patay BA, Pockros PJ, Scott ER, Simon RA, Williams GW, ... Schork NJ, et al. A genome sequencing program for novel undiagnosed diseases. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 25790160 DOI: 10.1038/gim.2015.21  0.4
2015 Ament SA, Szelinger S, Glusman G, Ashworth J, Hou L, Akula N, Shekhtman T, Badner JA, Brunkow ME, Mauldin DE, Stittrich AB, Rouleau K, Detera-Wadleigh SD, Nurnberger JI, Edenberg HJ, ... ... Schork N, et al. Rare variants in neuronal excitability genes influence risk for bipolar disorder. Proceedings of the National Academy of Sciences of the United States of America. 112: 3576-81. PMID 25730879 DOI: 10.1073/pnas.1424958112  0.52
2015 Pham PH, Shipman WJ, Erikson GA, Schork NJ, Torkamani A. Scripps Genome ADVISER: Annotation and Distributed Variant Interpretation SERver. Plos One. 10: e0116815. PMID 25706643 DOI: 10.1371/journal.pone.0116815  0.52
2015 Mangino M, Christiansen L, Stone R, Hunt SC, Horvath K, Eisenberg DT, Kimura M, Petersen I, Kark JD, Herbig U, Reiner AP, Benetos A, Codd V, Nyholt DR, Sinnreich R, ... ... Schork NJ, et al. DCAF4, a novel gene associated with leucocyte telomere length. Journal of Medical Genetics. 52: 157-62. PMID 25624462 DOI: 10.1136/jmedgenet-2014-102681  0.52
2015 Zhi X, Lamperska K, Golusinski P, Schork NJ, Luczewski L, Kolenda T, Golusinski W, Masternak MM. Gene expression analysis of head and neck squamous cell carcinoma survival and recurrence. Oncotarget. 6: 547-55. PMID 25575813  0.52
2015 Nievergelt CM, Maihofer AX, Mustapic M, Yurgil KA, Schork NJ, Miller MW, Logue MW, Geyer MA, Risbrough VB, O'Connor DT, Baker DG. Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene. Psychoneuroendocrinology. 51: 459-71. PMID 25456346 DOI: 10.1016/j.psyneuen.2014.10.017  0.52
2015 Tylee DS, Chandler SD, Nievergelt CM, Liu X, Pazol J, Woelk CH, Lohr JB, Kremen WS, Baker DG, Glatt SJ, Tsuang MT. Blood-based gene-expression biomarkers of post-traumatic stress disorder among deployed marines: A pilot study. Psychoneuroendocrinology. 51: 472-94. PMID 25311155 DOI: 10.1016/j.psyneuen.2014.09.024  0.52
2015 Boeldt DL, Schork NJ, Topol EJ, Bloss CS. Influence of individual differences in disease perception on consumer response to direct-to-consumer genomic testing. Clinical Genetics. 87: 225-32. PMID 24798746 DOI: 10.1111/cge.12419  0.52
2014 Norden-Krichmar TM, Gizer IR, Wilhelmsen KC, Schork NJ, Ehlers CL. Protective variant associated with alcohol dependence in a Mexican American cohort. Bmc Medical Genetics. 15: 136. PMID 25527893 DOI: 10.1186/s12881-014-0136-z  0.52
2014 Hoge CW, Castro CA, Yurgil KA, Barkauskas DA, Vasterling JJ, Nievergelt CM, Larson GE, Schork NJ, Litz BT, Nash WP, Baker DG. Treatment of generalized war-related health concerns placing TBI and PTSD in context Jama - Journal of the American Medical Association. 312: 1685-1686. PMID 25335151 DOI: 10.1001/jama.2014.6670  0.52
2014 Peng Q, Gizer IR, Libiger O, Bizon C, Wilhelmsen KC, Schork NJ, Ehlers CL. Association and ancestry analysis of sequence variants in ADH and ALDH using alcohol-related phenotypes in a Native American community sample. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 165: 673-83. PMID 25270064 DOI: 10.1002/ajmg.b.32272  0.52
2014 Goetz LH, Uribe-Bruce L, Quarless D, Libiger O, Schork NJ. Admixture and clinical phenotypic variation. Human Heredity. 77: 73-86. PMID 25060271 DOI: 10.1159/000362233  0.52
2014 Clarke TK, Crist RC, Doyle GA, Weiss AR, Brandt H, Crawford S, Crow S, Fichter MM, Halmi KA, Johnson C, Kaplan AS, La Via M, Mitchell JE, Strober M, Rotondo A, ... ... Schork NJ, et al. Characterization of genetic variation in the VGLL4 gene in anorexia nervosa. Psychiatric Genetics. 24: 183-4. PMID 24983835 DOI: 10.1097/YPG.0000000000000040  0.52
2014 Tewhey R, Gu B, Kelesidis T, Charlton C, Bobenchik A, Hindler J, Schork NJ, Humphries RM. Mechanisms of linezolid resistance among coagulase-negative staphylococci determined by whole-genome sequencing. Mbio. 5: e00894-14. PMID 24915435 DOI: 10.1128/mBio.00894-14  0.52
2014 Bright AT, Manary MJ, Tewhey R, Arango EM, Wang T, Schork NJ, Yanow SK, Winzeler EA. A high resolution case study of a patient with recurrent Plasmodium vivax infections shows that relapses were caused by meiotic siblings. Plos Neglected Tropical Diseases. 8: e2882. PMID 24901334 DOI: 10.1371/journal.pntd.0002882  0.52
2014 Levey DF, Le-Niculescu H, Frank J, Ayalew M, Jain N, Kirlin B, Learman R, Winiger E, Rodd Z, Shekhar A, Schork N, Kiefer F, Kiefe F, Wodarz N, Müller-Myhsok B, et al. Genetic risk prediction and neurobiological understanding of alcoholism. Translational Psychiatry. 4: e391. PMID 24844177 DOI: 10.1038/tp.2014.29  0.52
2014 Zhi X, Lamperska K, Golusinski P, Schork NJ, Luczewski L, Golusinski W, Masternak MM. Expression levels of insulin-like growth factors 1 and 2 in head and neck squamous cell carcinoma. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 24: 137-41. PMID 24802266 DOI: 10.1016/j.ghir.2014.04.003  0.52
2014 Rana BK, Darst BF, Bloss C, Shih PA, Depp C, Nievergelt CM, Allison M, Parsons JK, Schork N, Jeste DV. Candidate SNP associations of optimism and resilience in older adults: exploratory study of 935 community-dwelling adults. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 22: 997-1006.e5. PMID 24791650 DOI: 10.1016/j.jagp.2014.03.009  0.52
2014 Norden-Krichmar TM, Gizer IR, Libiger O, Wilhelmsen KC, Ehlers CL, Schork NJ. Correlation analysis of genetic admixture and social identification with body mass index in a Native American community. American Journal of Human Biology : the Official Journal of the Human Biology Council. 26: 347-60. PMID 24757035 DOI: 10.1002/ajhb.22521  0.52
2014 Chen YZ, Friedman JR, Chen DH, Chan GC, Bloss CS, Hisama FM, Topol SE, Carson AR, Pham PH, Bonkowski ES, Scott ER, Lee JK, Zhang G, Oliveira G, Xu J, ... ... Schork NJ, et al. Gain-of-function ADCY5 mutations in familial dyskinesia with facial myokymia. Annals of Neurology. 75: 542-9. PMID 24700542 DOI: 10.1002/ana.24119  0.52
2014 Peng Q, Schork NJ. Utility of network integrity methods in therapeutic target identification. Frontiers in Genetics. 5: 12. PMID 24550933 DOI: 10.3389/fgene.2014.00012  0.52
2014 Nievergelt CM, Wineinger NE, Libiger O, Pham P, Zhang G, Baker DG, Schork NJ. Chip-based direct genotyping of coding variants in genome wide association studies: utility, issues and prospects. Gene. 540: 104-9. PMID 24521671 DOI: 10.1016/j.gene.2014.01.069  0.52
2014 Zhang K, Huentelman MJ, Rao F, Sun EI, Corneveaux JJ, Schork AJ, Wei Z, Waalen J, Miramontes-Gonzalez JP, Hightower CM, Maihofer AX, Mahata M, Pastinen T, Ehret GB, ... Schork NJ, et al. Genetic implication of a novel thiamine transporter in human hypertension. Journal of the American College of Cardiology. 63: 1542-55. PMID 24509276 DOI: 10.1016/j.jacc.2014.01.007  0.52
2014 Yin X, Wineinger NE, Cheng H, Cui Y, Zhou F, Zuo X, Zheng X, Yang S, Schork NJ, Zhang X. Common variants explain a large fraction of the variability in the liability to psoriasis in a Han Chinese population. Bmc Genomics. 15: 87. PMID 24479639 DOI: 10.1186/1471-2164-15-87  0.52
2014 Corby PM, Biesbrock A, Gerlach R, Corby AL, Moreira A, Schork NJ, Bretz WA. Treatment responses to tooth whitening in twins. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 17: 23-6. PMID 24429255 DOI: 10.1017/thg.2013.87  0.52
2014 Yoneyama S, Guo Y, Lanktree MB, Barnes MR, Elbers CC, Karczewski KJ, Padmanabhan S, Bauer F, Baumert J, Beitelshees A, Berenson GS, Boer JM, Burke G, Cade B, Chen W, ... ... Schork NJ, et al. Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. Human Molecular Genetics. 23: 2498-510. PMID 24345515 DOI: 10.1093/hmg/ddt626  0.52
2014 Bloss CS, Schork NJ, Topol EJ. Direct-to-consumer pharmacogenomic testing is associated with increased physician utilisation. Journal of Medical Genetics. 51: 83-9. PMID 24343916 DOI: 10.1136/jmedgenet-2013-101909  0.52
2014 Yurgil KA, Barkauskas DA, Vasterling JJ, Nievergelt CM, Larson GE, Schork NJ, Litz BT, Nash WP, Baker DG. Association between traumatic brain injury and risk of posttraumatic stress disorder in active-duty Marines. Jama Psychiatry. 71: 149-57. PMID 24337530 DOI: 10.1001/jamapsychiatry.2013.3080  0.52
2014 Akshoomoff N, Newman E, Thompson WK, McCabe C, Bloss CS, Chang L, Amaral DG, Casey BJ, Ernst TM, Frazier JA, Gruen JR, Kaufmann WE, Kenet T, Kennedy DN, Libiger O, ... ... Schork N, et al. The NIH Toolbox Cognition Battery: results from a large normative developmental sample (PING). Neuropsychology. 28: 1-10. PMID 24219608 DOI: 10.1037/neu0000001  0.52
2014 Zhang K, Deacon DC, Rao F, Schork AJ, Fung MM, Waalen J, Schork NJ, Nievergelt CM, Chi NC, O'Connor DT. Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected]. Journal of the American College of Cardiology. 63: 358-68. PMID 24140660 DOI: 10.1016/j.jacc.2013.09.025  0.52
2014 Tranah GJ, Yokoyama JS, Katzman SM, Nalls MA, Newman AB, Harris TB, Cesari M, Manini TM, Schork NJ, Cummings SR, Liu Y, Yaffe K. Mitochondrial DNA sequence associations with dementia and amyloid-β in elderly African Americans. Neurobiology of Aging. 35: 442.e1-8. PMID 24140124 DOI: 10.1016/j.neurobiolaging.2013.05.023  0.52
2014 Ye X, Linton JM, Schork NJ, Buck LB, Petrascheck M. A pharmacological network for lifespan extension in Caenorhabditis elegans. Aging Cell. 13: 206-15. PMID 24134630 DOI: 10.1111/acel.12163  0.52
2014 Scott-Van Zeeland AA, Bloss CS, Tewhey R, Bansal V, Torkamani A, Libiger O, Duvvuri V, Wineinger N, Galvez L, Darst BF, Smith EN, Carson A, Pham P, Phillips T, Villarasa N, ... ... Schork NJ, et al. Evidence for the role of EPHX2 gene variants in anorexia nervosa. Molecular Psychiatry. 19: 724-32. PMID 23999524 DOI: 10.1038/mp.2013.91  0.52
2014 Darst BF, Madlensky L, Schork NJ, Topol EJ, Bloss CS. Characteristics of genomic test consumers who spontaneously share results with their health care provider. Health Communication. 29: 105-8. PMID 23384116 DOI: 10.1080/10410236.2012.717216  0.52
2013 Eicher JD, Powers NR, Miller LL, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork NJ, Darst BF, Casey BJ, Chang L, Ernst T, Frazier J, Kaufmann WE, Keating B, et al. Genome-wide association study of shared components of reading disability and language impairment. Genes, Brain, and Behavior. 12: 792-801. PMID 24024963 DOI: 10.1111/gbb.12085  0.52
2013 Paliwal A, Temkin AM, Kerkel K, Yale A, Yotova I, Drost N, Lax S, Nhan-Chang CL, Powell C, Borczuk A, Aviv A, Wapner R, Chen X, Nagy PL, Schork N, et al. Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation. Plos Genetics. 9: e1003622. PMID 24009515 DOI: 10.1371/journal.pgen.1003622  0.52
2013 Franceschini N, Fox E, Zhang Z, Edwards TL, Nalls MA, Sung YJ, Tayo BO, Sun YV, Gottesman O, Adeyemo A, Johnson AD, Young JH, Rice K, Duan Q, Chen F, ... ... Schork NJ, et al. Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. American Journal of Human Genetics. 93: 545-54. PMID 23972371 DOI: 10.1016/j.ajhg.2013.07.010  0.52
2013 Le-Niculescu H, Levey DF, Ayalew M, Palmer L, Gavrin LM, Jain N, Winiger E, Bhosrekar S, Shankar G, Radel M, Bellanger E, Duckworth H, Olesek K, Vergo J, Schweitzer R, ... ... Schork NJ, et al. Discovery and validation of blood biomarkers for suicidality. Molecular Psychiatry. 18: 1249-64. PMID 23958961 DOI: 10.1038/mp.2013.95  0.52
2013 Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, ... ... Schork NJ, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics. 45: 984-94. PMID 23933821 DOI: 10.1038/ng.2711  0.32
2013 Schork NJ. Genetic parts to a preventive medicine whole. Genome Medicine. 5: 54. PMID 23806045 DOI: 10.1186/gm458  0.52
2013 Wineinger NE, Harper A, Libiger O, Srinivasan SR, Chen W, Berenson GS, Schork NJ. Genomic risk models improve prediction of longitudinal lipid levels in children and young adults. Frontiers in Genetics. 4: 86. PMID 23734161 DOI: 10.3389/fgene.2013.00086  0.52
2013 Friese RS, Altshuler AE, Zhang K, Miramontes-Gonzalez JP, Hightower CM, Jirout ML, Salem RM, Gayen JR, Mahapatra NR, Biswas N, Cale M, Vaingankar SM, Kim HS, Courel M, Taupenot L, ... ... Schork NJ, et al. MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension. Human Molecular Genetics. 22: 3624-40. PMID 23674521 DOI: 10.1093/hmg/ddt213  0.52
2013 Schork AJ, Thompson WK, Pham P, Torkamani A, Roddey JC, Sullivan PF, Kelsoe JR, O'Donovan MC, Furberg H, Schork NJ, Andreassen OA, Dale AM. All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. Plos Genetics. 9: e1003449. PMID 23637621 DOI: 10.1371/journal.pgen.1003449  0.52
2013 Demerath EW, Liu CT, Franceschini N, Chen G, Palmer JR, Smith EN, Chen CT, Ambrosone CB, Arnold AM, Bandera EV, Berenson GS, Bernstein L, Britton A, Cappola AR, Carlson CS, ... ... Schork NJ, et al. Genome-wide association study of age at menarche in African-American women. Human Molecular Genetics. 22: 3329-46. PMID 23599027 DOI: 10.1093/hmg/ddt181  0.52
2013 Darst BF, Madlensky L, Schork NJ, Topol EJ, Bloss CS. Perceptions of genetic counseling services in direct-to-consumer personal genomic testing. Clinical Genetics. 84: 335-9. PMID 23590221 DOI: 10.1111/cge.12166  0.52
2013 Bloss CS, Wineinger NE, Darst BF, Schork NJ, Topol EJ. Impact of direct-to-consumer genomic testing at long term follow-up. Journal of Medical Genetics. 50: 393-400. PMID 23559530 DOI: 10.1136/jmedgenet-2012-101207  0.52
2013 Peterson SN, Snesrud E, Liu J, Ong AC, Kilian M, Schork NJ, Bretz W. The dental plaque microbiome in health and disease. Plos One. 8: e58487. PMID 23520516 DOI: 10.1371/journal.pone.0058487  0.52
2013 Petersen DC, Libiger O, Tindall EA, Hardie RA, Hannick LI, Glashoff RH, Mukerji M, Fernandez P, Haacke W, Schork NJ, Hayes VM. Complex patterns of genomic admixture within southern Africa. Plos Genetics. 9: e1003309. PMID 23516368 DOI: 10.1371/journal.pgen.1003309  0.52
2013 Greenwood TA, Swerdlow NR, Gur RE, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Green MF, Gur RC, Lazzeroni LC, Nuechterlein KH, Olincy A, Radant AD, Ray A, Schork NJ, et al. Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. The American Journal of Psychiatry. 170: 521-32. PMID 23511790 DOI: 10.1176/appi.ajp.2012.12020186  0.52
2013 Schmitz RJ, Schultz MD, Urich MA, Nery JR, Pelizzola M, Libiger O, Alix A, McCosh RB, Chen H, Schork NJ, Ecker JR. Patterns of population epigenomic diversity. Nature. 495: 193-8. PMID 23467092 DOI: 10.1038/nature11968  0.52
2013 Greenwood TA, Kelsoe JR. Genome-wide association study of irritable vs. elated mania suggests genetic differences between clinical subtypes of bipolar disorder. Plos One. 8: e53804. PMID 23326512 DOI: 10.1371/journal.pone.0053804  0.52
2013 Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Franceschini N, ... ... Schork NJ, et al. Loci influencing blood pressure identified using a cardiovascular gene-centric array. Human Molecular Genetics. 22: 1663-78. PMID 23303523 DOI: 10.1093/hmg/dds555  0.52
2013 Deo R, Nalls MA, Avery CL, Smith JG, Evans DS, Keller MF, Butler AM, Buxbaum SG, Li G, Miguel Quibrera P, Smith EN, Tanaka T, Akylbekova EL, Alonso A, Arking DE, ... ... Schork NJ, et al. Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 10: 401-8. PMID 23183192 DOI: 10.1016/j.hrthm.2012.11.014  0.52
2013 Bailer UF, Frank GK, Price JC, Meltzer CC, Becker C, Mathis CA, Wagner A, Barbarich-Marsteller NC, Bloss CS, Putnam K, Schork NJ, Gamst A, Kaye WH. Interaction between serotonin transporter and dopamine D2/D3 receptor radioligand measures is associated with harm avoidant symptoms in anorexia and bulimia nervosa. Psychiatry Research. 211: 160-8. PMID 23154100 DOI: 10.1016/j.pscychresns.2012.06.010  0.52
2013 Chen C, Cheng L, Grennan K, Pibiri F, Zhang C, Badner JA, Kelsoe JR, Greenwood TA, Nievergelt CM, Barrett TB, McKinney R, Shilling PD, Schork NJ, Smith EN, Bloss CS, et al. Two gene co-expression modules differentiate psychotics and controls Molecular Psychiatry. 18: 1308-1314. PMID 23147385 DOI: 10.1038/mp.2012.146  0.52
2013 Vélez JI, Chandrasekharappa SC, Henao E, Martinez AF, Harper U, Jones M, Solomon BD, Lopez L, Garcia G, Aguirre-Acevedo DC, Acosta-Baena N, Correa JC, Lopera-Gómez CM, Jaramillo-Elorza MC, Rivera D, ... ... Schork NJ, et al. Pooling/bootstrap-based GWAS (pbGWAS) identifies new loci modifying the age of onset in PSEN1 p.Glu280Ala Alzheimer's disease. Molecular Psychiatry. 18: 568-75. PMID 22710270 DOI: 10.1038/mp.2012.81  0.52
2013 Gamazon ER, Badner JA, Cheng L, Zhang C, Zhang D, Cox NJ, Gershon ES, Kelsoe JR, Greenwood TA, Nievergelt CM, Chen C, McKinney R, Shilling PD, Schork NJ, Smith EN, et al. Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants. Molecular Psychiatry. 18: 340-6. PMID 22212596 DOI: 10.1038/mp.2011.174  0.52
2012 Miller MB, Basu S, Cunningham J, Eskin E, Malone SM, Oetting WS, Schork N, Sul JH, Iacono WG, McGue M. The Minnesota Center for Twin and Family Research genome-wide association study. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 15: 767-74. PMID 23363460 DOI: 10.1017/thg.2012.62  0.52
2012 Libiger O, Schork NJ. A Method for Inferring an Individual's Genetic Ancestry and Degree of Admixture Associated with Six Major Continental Populations. Frontiers in Genetics. 3: 322. PMID 23335941 DOI: 10.3389/fgene.2012.00322  0.52
2012 Walhovd KB, Fjell AM, Brown TT, Kuperman JM, Chung Y, Hagler DJ, Roddey JC, Erhart M, McCabe C, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork NJ, Darst BF, et al. Long-term influence of normal variation in neonatal characteristics on human brain development. Proceedings of the National Academy of Sciences of the United States of America. 109: 20089-94. PMID 23169628 DOI: 10.1073/pnas.1208180109  0.52
2012 Smith JG, Avery CL, Evans DS, Nalls MA, Meng YA, Smith EN, Palmer C, Tanaka T, Mehra R, Butler AM, Young T, Buxbaum SG, Kerr KF, Berenson GS, Schnabel RB, ... ... Schork NJ, et al. Impact of ancestry and common genetic variants on QT interval in African Americans. Circulation. Cardiovascular Genetics. 5: 647-55. PMID 23166209 DOI: 10.1161/CIRCGENETICS.112.962787  0.52
2012 Fjell AM, Walhovd KB, Brown TT, Kuperman JM, Chung Y, Hagler DJ, Venkatraman V, Roddey JC, Erhart M, McCabe C, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Darst BF, ... Schork NJ, et al. Multimodal imaging of the self-regulating developing brain. Proceedings of the National Academy of Sciences of the United States of America. 109: 19620-5. PMID 23150548 DOI: 10.1073/pnas.1208243109  0.52
2012 Butler AM, Yin X, Evans DS, Nalls MA, Smith EN, Tanaka T, Li G, Buxbaum SG, Whitsel EA, Alonso A, Arking DE, Benjamin EJ, Berenson GS, Bis JC, Chen W, ... ... Schork NJ, et al. Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts. Circulation. Cardiovascular Genetics. 5: 639-46. PMID 23139255 DOI: 10.1161/CIRCGENETICS.112.963991  0.52
2012 Torkamani A, Pham P, Libiger O, Bansal V, Zhang G, Scott-Van Zeeland AA, Tewhey R, Topol EJ, Schork NJ. Clinical implications of human population differences in genome-wide rates of functional genotypes. Frontiers in Genetics. 3: 211. PMID 23125845 DOI: 10.3389/fgene.2012.00211  0.52
2012 Vassy JL, Dasmahapatra P, Meigs JB, Schork NJ, Magnussen CG, Chen W, Raitakari OT, Pencina MJ, Jamal SM, Berenson GS, Goodman E. Genotype prediction of adult type 2 diabetes from adolescence in a multiracial population. Pediatrics. 130: e1235-42. PMID 23071215 DOI: 10.1542/peds.2012-1132  0.52
2012 Asselbergs FW, Guo Y, van Iperen EP, Sivapalaratnam S, Tragante V, Lanktree MB, Lange LA, Almoguera B, Appelman YE, Barnard J, Baumert J, Beitelshees AL, Bhangale TR, Chen YD, Gaunt TR, ... ... Schork NJ, et al. Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. American Journal of Human Genetics. 91: 823-38. PMID 23063622 DOI: 10.1016/j.ajhg.2012.08.032  0.52
2012 Zapala MA, Schork NJ. Statistical properties of multivariate distance matrix regression for high-dimensional data analysis. Frontiers in Genetics. 3: 190. PMID 23060897 DOI: 10.3389/fgene.2012.00190  0.52
2012 Nissen S, Liang S, Shehktman T, Kelsoe JR, Greenwood TA, Nievergelt CM, McKinney R, Shilling PD, Smith EN, Schork NJ, Bloss CS, Nurnberger JI, Edenberg HJ, Foroud T, et al. Evidence for association of bipolar disorder to haplotypes in the 22q12.3 region near the genes stargazin, IFT27 and parvalbumin. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 941-50. PMID 23038240 DOI: 10.1002/ajmg.b.32099  0.52
2012 Verma-Gaur J, Torkamani A, Schaffer L, Head SR, Schork NJ, Feeney AJ. Noncoding transcription within the Igh distal V(H) region at PAIR elements affects the 3D structure of the Igh locus in pro-B cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 17004-9. PMID 23027941 DOI: 10.1073/pnas.1208398109  0.52
2012 Zhang K, Rao F, Miramontes-Gonzalez JP, Hightower CM, Vaught B, Chen Y, Greenwood TA, Schork AJ, Wang L, Mahata M, Stridsberg M, Khandrika S, Biswas N, Fung MM, Waalen J, ... ... Schork NJ, et al. Neuropeptide Y (NPY): genetic variation in the human promoter alters glucocorticoid signaling, yielding increased NPY secretion and stress responses. Journal of the American College of Cardiology. 60: 1678-89. PMID 23021333 DOI: 10.1016/j.jacc.2012.06.042  0.52
2012 Tewhey R, Cannavino CR, Leake JA, Bansal V, Topol EJ, Torkamani A, Bradley JS, Schork NJ. Genetic structure of community acquired methicillin-resistant Staphylococcus aureus USA300. Bmc Genomics. 13: 508. PMID 23009684 DOI: 10.1186/1471-2164-13-508  0.52
2012 Mangino M, Hwang SJ, Spector TD, Hunt SC, Kimura M, Fitzpatrick AL, Christiansen L, Petersen I, Elbers CC, Harris T, Chen W, Srinivasan SR, Kark JD, Benetos A, El Shamieh S, ... ... Schork NJ, et al. Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans. Human Molecular Genetics. 21: 5385-94. PMID 23001564 DOI: 10.1093/hmg/dds382  0.52
2012 Humphries RM, Kelesidis T, Tewhey R, Rose WE, Schork N, Nizet V, Sakoulas G. Genotypic and phenotypic evaluation of the evolution of high-level daptomycin nonsusceptibility in vancomycin-resistant Enterococcus faecium. Antimicrobial Agents and Chemotherapy. 56: 6051-3. PMID 22948885 DOI: 10.1128/AAC.01318-12  0.52
2012 Pallmann P, Schaarschmidt F, Hothorn LA, Fischer C, Nacke H, Priesnitz KU, Schork NJ. Assessing group differences in biodiversity by simultaneously testing a user-defined selection of diversity indices. Molecular Ecology Resources. 12: 1068-78. PMID 22934781 DOI: 10.1111/1755-0998.12004  0.52
2012 Glatt SJ, Tsuang MT, Winn M, Chandler SD, Collins M, Lopez L, Weinfeld M, Carter C, Schork N, Pierce K, Courchesne E. Blood-based gene expression signatures of infants and toddlers with autism. Journal of the American Academy of Child and Adolescent Psychiatry. 51: 934-44.e2. PMID 22917206 DOI: 10.1016/j.jaac.2012.07.007  0.52
2012 Mei H, Chen W, Mills K, He J, Srinivasan SR, Schork N, Murray S, Berenson GS. Influences of FTO gene on onset age of adult overweight. Human Genetics. 131: 1851-9. PMID 22842737 DOI: 10.1007/s00439-012-1204-0  0.52
2012 Bright AT, Tewhey R, Abeles S, Chuquiyauri R, Llanos-Cuentas A, Ferreira MU, Schork NJ, Vinetz JM, Winzeler EA. Whole genome sequencing analysis of Plasmodium vivax using whole genome capture. Bmc Genomics. 13: 262. PMID 22721170 DOI: 10.1186/1471-2164-13-262  0.52
2012 Price MJ, Murray SS, Angiolillo DJ, Lillie E, Smith EN, Tisch RL, Schork NJ, Teirstein PS, Topol EJ. Influence of genetic polymorphisms on the effect of high- and standard-dose clopidogrel after percutaneous coronary intervention: the GIFT (Genotype Information and Functional Testing) study. Journal of the American College of Cardiology. 59: 1928-37. PMID 22624833 DOI: 10.1016/j.jacc.2011.11.068  0.52
2012 Ayalew M, Le-Niculescu H, Levey DF, Jain N, Changala B, Patel SD, Winiger E, Breier A, Shekhar A, Amdur R, Koller D, Nurnberger JI, Corvin A, Geyer M, Tsuang MT, ... ... Schork NJ, et al. Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction. Molecular Psychiatry. 17: 887-905. PMID 22584867 DOI: 10.1038/mp.2012.37  0.52
2012 Baker DG, Nash WP, Litz BT, Geyer MA, Risbrough VB, Nievergelt CM, O'Connor DT, Larson GE, Schork NJ, Vasterling JJ, Hammer PS, Webb-Murphy JA. Predictors of risk and resilience for posttraumatic stress disorder among ground combat Marines: methods of the Marine Resiliency Study. Preventing Chronic Disease. 9: E97. PMID 22575082 DOI: 10.5888/pcd9.110134  0.52
2012 Chow ML, Pramparo T, Winn ME, Barnes CC, Li HR, Weiss L, Fan JB, Murray S, April C, Belinson H, Fu XD, Wynshaw-Boris A, Schork NJ, Courchesne E. Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. Plos Genetics. 8: e1002592. PMID 22457638 DOI: 10.1371/journal.pgen.1002592  0.52
2012 Damani S, Bacconi A, Libiger O, Chourasia AH, Serry R, Gollapudi R, Goldberg R, Rapeport K, Haaser S, Topol S, Knowlton S, Bethel K, Kuhn P, Wood M, Carragher B, ... Schork NJ, et al. Characterization of circulating endothelial cells in acute myocardial infarction. Science Translational Medicine. 4: 126ra33. PMID 22440735 DOI: 10.1126/scitranslmed.3003451  0.52
2012 Chow ML, Winn ME, Li HR, April C, Wynshaw-Boris A, Fan JB, Fu XD, Courchesne E, Schork NJ. Preprocessing and Quality Control Strategies for Illumina DASL Assay-Based Brain Gene Expression Studies with Semi-Degraded Samples. Frontiers in Genetics. 3: 11. PMID 22375143 DOI: 10.3389/fgene.2012.00011  0.52
2012 Mei H, Chen W, Jiang F, He J, Srinivasan S, Smith EN, Schork N, Murray S, Berenson GS. Longitudinal replication studies of GWAS risk SNPs influencing body mass index over the course of childhood and adulthood. Plos One. 7: e31470. PMID 22355368 DOI: 10.1371/journal.pone.0031470  0.52
2012 Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, ... ... Schork NJ, et al. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proceedings of the National Academy of Sciences of the United States of America. 109: 3985-90. PMID 22343285 DOI: 10.1073/pnas.1105829109  0.52
2012 Hernesniemi JA, Seppälä I, Lyytikäinen LP, Mononen N, Oksala N, Hutri-Kähönen N, Juonala M, Taittonen L, Smith EN, Schork NJ, Chen W, Srinivasan SR, Berenson GS, Murray SS, Laitinen T, et al. Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta-analysis of three independent studies. Plos One. 7: e28931. PMID 22295058 DOI: 10.1371/journal.pone.0028931  0.52
2012 Aoki-Ota M, Torkamani A, Ota T, Schork N, Nemazee D. Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing. Journal of Immunology (Baltimore, Md. : 1950). 188: 2305-15. PMID 22287713 DOI: 10.4049/jimmunol.1103484  0.52
2012 Bloss CS, Topol EJ, Schork NJ. Association of direct-to-consumer genome-wide disease risk estimates and self-reported disease. Genetic Epidemiology. 36: 66-70. PMID 22127769 DOI: 10.1002/gepi.20664  0.52
2012 Torkamani A, Schork NJ. Background gene expression networks significantly enhance drug response prediction by transcriptional profiling. The Pharmacogenomics Journal. 12: 446-52. PMID 21826086 DOI: 10.1038/tpj.2011.35  0.52
2012 Fung MM, Salem RM, Lipkowitz MS, Bhatnagar V, Pandey B, Schork NJ, O'Connor DT. Methylenetetrahydrofolate reductase (MTHFR) polymorphism A1298C (Glu429Ala) predicts decline in renal function over time in the African-American Study of Kidney Disease and Hypertension (AASK) Trial and Veterans Affairs Hypertension Cohort (VAHC). Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 27: 197-205. PMID 21613384 DOI: 10.1093/ndt/gfr257  0.52
2012 Friedman AJ, Torkamani A, Verkhivker G, Schork NJ. From coding variant to structure and function insight Proteomics Research Journal. 3: 395-405.  0.52
2011 Le-Niculescu H, Balaraman Y, Patel SD, Ayalew M, Gupta J, Kuczenski R, Shekhar A, Schork N, Geyer MA, Niculescu AB. Convergent functional genomics of anxiety disorders: translational identification of genes, biomarkers, pathways and mechanisms. Translational Psychiatry. 1: e9. PMID 22832404 DOI: 10.1038/tp.2011.9  0.52
2011 Bretz WA, Biesbrock A, Corby PM, Corby AL, Bretz WG, Wessel J, Schork NJ. Environmental and genetic contributions to indicators of oral malodor in twins. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 14: 568-72. PMID 22506313 DOI: 10.1375/twin.14.6.568  0.52
2011 Sebastiani P, Riva A, Montano M, Pham P, Torkamani A, Scherba E, Benson G, Milton JN, Baldwin CT, Andersen S, Schork NJ, Steinberg MH, Perls TT. Whole genome sequences of a male and female supercentenarian, ages greater than 114 years. Frontiers in Genetics. 2: 90. PMID 22303384 DOI: 10.3389/fgene.2011.00090  0.52
2011 Tiwari HK, Schork NJ. Grand challenges in statistical genetics/genomics methodology. Frontiers in Genetics. 2: 5. PMID 22303304 DOI: 10.3389/fgene.2011.00005  0.52
2011 Bloss CS, Madlensky L, Schork NJ, Topol EJ. Genomic information as a behavioral health intervention: can it work? Personalized Medicine. 8: 659-667. PMID 22199991 DOI: 10.2217/pme.11.73  0.52
2011 Vrieze SI, McGue M, Miller MB, Legrand LN, Schork NJ, Iacono WG. An assessment of the individual and collective effects of variants on height using twins and a developmentally informative study design. Plos Genetics. 7: e1002413. PMID 22174699 DOI: 10.1371/journal.pgen.1002413  0.52
2011 Miller VM, Kaplan JR, Schork NJ, Ouyang P, Berga SL, Wenger NK, Shaw LJ, Webb RC, Mallampalli M, Steiner M, Taylor DA, Merz CN, Reckelhoff JF. Strategies and methods to study sex differences in cardiovascular structure and function: a guide for basic scientists. Biology of Sex Differences. 2: 14. PMID 22152231 DOI: 10.1186/2042-6410-2-14  0.52
2011 Oikonen M, Tikkanen E, Juhola J, Tuovinen T, Seppälä I, Juonala M, Taittonen L, Mikkilä V, Kähönen M, Ripatti S, Viikari J, Lehtimäki T, Havulinna AS, Kee F, Newton-Cheh C, ... ... Schork NJ, et al. Genetic variants and blood pressure in a population-based cohort: the Cardiovascular Risk in Young Finns study. Hypertension. 58: 1079-85. PMID 22025373 DOI: 10.1161/HYPERTENSIONAHA.111.179291  0.52
2011 Sklar P, Ripke S, Scott LJ, Andreassen OA, Cichon S, Craddock N, Edenberg HJ, Nurnberger JI, Rietschel M, Blackwood D, Corvin A, Flickinger M, Guan W, Mattingsdal M, McQuillin A, ... ... Schork NJ, et al. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4 Nature Genetics. 43: 977-985. PMID 21926972 DOI: 10.1038/ng.943  0.52
2011 Schmitz RJ, Schultz MD, Lewsey MG, O'Malley RC, Urich MA, Libiger O, Schork NJ, Ecker JR. Transgenerational epigenetic instability is a source of novel methylation variants. Science (New York, N.Y.). 334: 369-73. PMID 21921155 DOI: 10.1126/science.1212959  0.52
2011 Chow ML, Li HR, Winn ME, April C, Barnes CC, Wynshaw-Boris A, Fan JB, Fu XD, Courchesne E, Schork NJ. Genome-wide expression assay comparison across frozen and fixed postmortem brain tissue samples. Bmc Genomics. 12: 449. PMID 21906392 DOI: 10.1186/1471-2164-12-449  0.52
2011 Bakken TE, Dale AM, Schork NJ. A geographic cline of skull and brain morphology among individuals of European Ancestry. Human Heredity. 72: 35-44. PMID 21849792 DOI: 10.1159/000330168  0.52
2011 Winn ME, Shaw M, April C, Klotzle B, Fan JB, Murray SS, Schork NJ. Gene expression profiling of human whole blood samples with the Illumina WG-DASL assay. Bmc Genomics. 12: 412. PMID 21843359 DOI: 10.1186/1471-2164-12-412  0.52
2011 Torkamani A, Scott-Van Zeeland AA, Topol EJ, Schork NJ. Annotating individual human genomes. Genomics. 98: 233-41. PMID 21839162 DOI: 10.1016/j.ygeno.2011.07.006  0.52
2011 Bloss CS, Darst BF, Topol EJ, Schork NJ. Direct-to-consumer personalized genomic testing. Human Molecular Genetics. 20: R132-41. PMID 21828075 DOI: 10.1093/hmg/ddr349  0.52
2011 Bakken TE, Bloss CS, Roddey JC, Joyner AH, Rimol LM, Djurovic S, Melle I, Sundet K, Agartz I, Andreassen OA, Dale AM, Schork NJ. Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia. Archives of General Psychiatry. 68: 781-90. PMID 21810643 DOI: 10.1001/archgenpsychiatry.2011.81  0.52
2011 Root TL, Szatkiewicz JP, Jonassaint CR, Thornton LM, Pinheiro AP, Strober M, Bloss C, Berrettini W, Schork NJ, Kaye WH, Bergen AW, Magistretti P, Brandt H, Crawford S, Crow S, et al. Association of candidate genes with phenotypic traits relevant to anorexia nervosa. European Eating Disorders Review : the Journal of the Eating Disorders Association. 19: 487-93. PMID 21780254 DOI: 10.1002/erv.1138  0.52
2011 Bloss CS, Berrettini W, Bergen AW, Magistretti P, Duvvuri V, Strober M, Brandt H, Crawford S, Crow S, Fichter MM, Halmi KA, Johnson C, Kaplan AS, Keel P, Klump KL, ... ... Schork NJ, et al. Genetic association of recovery from eating disorders: the role of GABA receptor SNPs. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2222-32. PMID 21750581 DOI: 10.1038/npp.2011.108  0.52
2011 Smith EN, Koller DL, Panganiban C, Szelinger S, Zhang P, Badner JA, Barrett TB, Berrettini WH, Bloss CS, Byerley W, Coryell W, Edenberg HJ, Foroud T, Gershon ES, Greenwood TA, ... ... Schork NJ, et al. Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes. Plos Genetics. 7: e1002134. PMID 21738484 DOI: 10.1371/journal.pgen.1002134  0.52
2011 Luo W, Schork NJ, Marschke KB, Ng SC, Hermann TW, Zhang J, Sanders JM, Tooker P, Malo N, Zapala MA, Dziewanowska ZE, Negro-Vilar A, Meglasson MD. Identification of polymorphisms associated with hypertriglyceridemia and prolonged survival induced by bexarotene in treating non-small cell lung cancer. Anticancer Research. 31: 2303-11. PMID 21737656  0.52
2011 Peterson SN, Snesrud E, Schork NJ, Bretz WA. Dental caries pathogenicity: a genomic and metagenomic perspective. International Dental Journal. 61: 11-22. PMID 21726221 DOI: 10.1111/j.1875-595X.2011.00025.x  0.52
2011 Lillie EO, Patay B, Diamant J, Issell B, Topol EJ, Schork NJ. The n-of-1 clinical trial: the ultimate strategy for individualizing medicine? Personalized Medicine. 8: 161-173. PMID 21695041 DOI: 10.2217/pme.11.7  0.52
2011 Degner SC, Verma-Gaur J, Wong TP, Bossen C, Iverson GM, Torkamani A, Vettermann C, Lin YC, Ju Z, Schulz D, Murre CS, Birshtein BK, Schork NJ, Schlissel MS, Riblet R, et al. CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 9566-71. PMID 21606361 DOI: 10.1073/pnas.1019391108  0.52
2011 Bansal V, Tewhey R, Leproust EM, Schork NJ. Efficient and cost effective population resequencing by pooling and in-solution hybridization. Plos One. 6: e18353. PMID 21479135 DOI: 10.1371/journal.pone.0018353  0.52
2011 Pramparo T, Libiger O, Jain S, Li H, Youn YH, Hirotsune S, Schork NJ, Wynshaw-Boris A. Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects. Plos Genetics. 7: e1001331. PMID 21423666 DOI: 10.1371/journal.pgen.1001331  0.52
2011 Cheng J, Torkamani A, Grover RK, Jones TM, Ruiz DI, Schork NJ, Quigley MM, Hall FW, Salomon DR, Lerner RA. Ectopic B-cell clusters that infiltrate transplanted human kidneys are clonal. Proceedings of the National Academy of Sciences of the United States of America. 108: 5560-5. PMID 21415369 DOI: 10.1073/pnas.1101148108  0.52
2011 Price MJ, Berger PB, Teirstein PS, Tanguay JF, Angiolillo DJ, Spriggs D, Puri S, Robbins M, Garratt KN, Bertrand OF, Stillabower ME, Stillablower ME, Aragon JR, Kandzari DE, Stinis CT, ... ... Schork NJ, et al. Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: the GRAVITAS randomized trial. Jama. 305: 1097-105. PMID 21406646 DOI: 10.1001/jama.2011.290  0.52
2011 Topol EJ, Schork NJ, Smith JM. Digital medicine and the Scripps Translational Science Institute. Clinical and Translational Science. 4: 8-9. PMID 21348949 DOI: 10.1111/j.1752-8062.2010.00256.x  0.52
2011 Bloss CS, Jeste DV, Schork NJ. Genomics for disease treatment and prevention. The Psychiatric Clinics of North America. 34: 147-66. PMID 21333845 DOI: 10.1016/j.psc.2010.11.005  0.52
2011 Tewhey R, Bansal V, Torkamani A, Topol EJ, Schork NJ. The importance of phase information for human genomics. Nature Reviews. Genetics. 12: 215-23. PMID 21301473 DOI: 10.1038/nrg2950  0.52
2011 Stone WS, Giuliano AJ, Tsuang MT, Braff DL, Cadenhead KS, Calkins ME, Dobie DJ, Faraone SV, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, ... ... Schork NJ, et al. Group and site differences on the California Verbal Learning Test in persons with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia (COGS). Schizophrenia Research. 128: 102-10. PMID 21288694 DOI: 10.1016/j.schres.2011.01.005  0.52
2011 Bloss CS, Schork NJ, Topol EJ. Effect of direct-to-consumer genomewide profiling to assess disease risk. The New England Journal of Medicine. 364: 524-34. PMID 21226570 DOI: 10.1056/NEJMoa1011893  0.52
2011 Bansal V, Tewhey R, Topol EJ, Schork NJ. The next phase in human genetics. Nature Biotechnology. 29: 38-9. PMID 21221098 DOI: 10.1038/nbt.1757  0.52
2011 Topol EJ, Schork NJ. Catapulting clopidogrel pharmacogenomics forward. Nature Medicine. 17: 40-1. PMID 21217678 DOI: 10.1038/nm0111-40  0.52
2011 Bansal V, Libiger O, Torkamani A, Schork NJ. An application and empirical comparison of statistical analysis methods for associating rare variants to a complex phenotype. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 76-87. PMID 21121035  0.52
2011 Wang K, Zhang H, Bloss CS, Duvvuri V, Kaye W, Schork NJ, Berrettini W, Hakonarson H. A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa. Molecular Psychiatry. 16: 949-59. PMID 21079607 DOI: 10.1038/mp.2010.107  0.52
2011 McLachlan S, Lee SM, Steele TM, Hawthorne PL, Zapala MA, Eskin E, Schork NJ, Anderson GJ, Vulpe CD. In silico QTL mapping of basal liver iron levels in inbred mouse strains. Physiological Genomics. 43: 136-47. PMID 21062905 DOI: 10.1152/physiolgenomics.00025.2010  0.52
2011 Bailer UF, Bloss CS, Frank GK, Price JC, Meltzer CC, Mathis CA, Geyer MA, Wagner A, Becker CR, Schork NJ, Kaye WH. 5-HT₁A receptor binding is increased after recovery from bulimia nervosa compared to control women and is associated with behavioral inhibition in both groups. The International Journal of Eating Disorders. 44: 477-87. PMID 20872754 DOI: 10.1002/eat.20843  0.52
2011 Bloss CS, Pawlikowska L, Schork NJ. Contemporary human genetic strategies in aging research. Ageing Research Reviews. 10: 191-200. PMID 20709627 DOI: 10.1016/j.arr.2010.07.005  0.52
2011 Kurian SM, Le-Niculescu H, Patel SD, Bertram D, Davis J, Dike C, Yehyawi N, Lysaker P, Dustin J, Caligiuri M, Lohr J, Lahiri DK, Nurnberger JI, Faraone SV, Geyer MA, ... ... Schork NJ, et al. Identification of blood biomarkers for psychosis using convergent functional genomics. Molecular Psychiatry. 16: 37-58. PMID 19935739 DOI: 10.1038/mp.2009.117  0.52
2011 Bloss CS, Schork NJ, Topol EJ. The authors reply New England Journal of Medicine. 364: 2075. DOI: 10.1056/NEJMc1103704  0.52
2010 Salem RM, Pandey B, Richard E, Fung MM, Garcia EP, Brophy VH, Schork NJ, O'Connor DT, Bhatnagar V. The VA Hypertension Primary Care Longitudinal Cohort: Electronic medical records in the post-genomic era. Health Informatics Journal. 16: 274-86. PMID 21216807 DOI: 10.1177/1460458210380527  0.52
2010 Kerkel K, Schupf N, Hatta K, Pang D, Salas M, Kratz A, Minden M, Murty V, Zigman WB, Mayeux RP, Jenkins EC, Torkamani A, Schork NJ, Silverman W, Croy BA, et al. Altered DNA methylation in leukocytes with trisomy 21. Plos Genetics. 6: e1001212. PMID 21124956 DOI: 10.1371/journal.pgen.1001212  0.52
2010 Bhatia G, Bansal V, Harismendy O, Schork NJ, Topol EJ, Frazer K, Bafna V. A covering method for detecting genetic associations between rare variants and common phenotypes. Plos Computational Biology. 6: e1000954. PMID 20976246 DOI: 10.1371/journal.pcbi.1000954  0.52
2010 Bansal V, Libiger O, Torkamani A, Schork NJ. Statistical analysis strategies for association studies involving rare variants. Nature Reviews. Genetics. 11: 773-85. PMID 20940738 DOI: 10.1038/nrg2867  0.52
2010 Rosenberg S, Elashoff MR, Beineke P, Daniels SE, Wingrove JA, Tingley WG, Sager PT, Sehnert AJ, Yau M, Kraus WE, Newby LK, Schwartz RS, Voros S, Ellis SG, Tahirkheli N, ... ... Schork NJ, et al. Multicenter validation of the diagnostic accuracy of a blood-based gene expression test for assessing obstructive coronary artery disease in nondiabetic patients. Annals of Internal Medicine. 153: 425-34. PMID 20921541 DOI: 10.7326/0003-4819-153-7-201010050-00005  0.52
2010 Smith EN, Chen W, Kähönen M, Kettunen J, Lehtimäki T, Peltonen L, Raitakari OT, Salem RM, Schork NJ, Shaw M, Srinivasan SR, Topol EJ, Viikari JS, Berenson GS, Murray SS. Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study. Plos Genetics. 6: e1001094. PMID 20838585 DOI: 10.1371/journal.pgen.1001094  0.52
2010 Mei H, Chen W, Srinivasan SR, Jiang F, Schork N, Murray S, Smith E, So JD, Berenson GS. FTO influences on longitudinal BMI over childhood and adulthood and modulation on relationship between birth weight and longitudinal BMI. Human Genetics. 128: 589-96. PMID 20811910 DOI: 10.1007/s00439-010-0883-7  0.52
2010 Bloss CS, Ornowski L, Silver E, Cargill M, Vanier V, Schork NJ, Topol EJ. Consumer perceptions of direct-to-consumer personalized genomic risk assessments. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 12: 556-66. PMID 20717041 DOI: 10.1097/GIM.0b013e3181eb51c6  0.52
2010 Lakatos A, Derbeneva O, Younes D, Keator D, Bakken T, Lvova M, Brandon M, Guffanti G, Reglodi D, Saykin A, Weiner M, Macciardi F, Schork N, Wallace DC, Potkin SG, et al. Association between mitochondrial DNA variations and Alzheimer's disease in the ADNI cohort. Neurobiology of Aging. 31: 1355-63. PMID 20538375 DOI: 10.1016/j.neurobiolaging.2010.04.031  0.52
2010 Chen Y, Lipkowitz MS, Salem RM, Fung MM, Bhatnagar V, Mahata M, Nievergelt CM, Rao F, Mahata SK, Schork NJ, Hicks PJ, Bowden DW, Freedman BI, Brophy VH, O'Connor DT, et al. Progression of chronic kidney disease: Adrenergic genetic influence on glomerular filtration rate decline in hypertensive nephrosclerosis. American Journal of Nephrology. 32: 23-30. PMID 20484896 DOI: 10.1159/000313927  0.52
2010 Winn ME, Zapala MA, Hovatta I, Risbrough VB, Lillie E, Schork NJ. The effects of globin on microarray-based gene expression analysis of mouse blood. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 21: 268-75. PMID 20473674 DOI: 10.1007/s00335-010-9261-y  0.52
2010 Pinheiro AP, Bulik CM, Thornton LM, Sullivan PF, Root TL, Bloss CS, Berrettini WH, Schork NJ, Kaye WH, Bergen AW, Magistretti P, Brandt H, Crawford S, Crow S, Fichter MM, et al. Association study of 182 candidate genes in anorexia nervosa. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 1070-80. PMID 20468064 DOI: 10.1002/ajmg.b.31082  0.52
2010 Bloss CS, Schiabor KM, Schork NJ. Human behavioral informatics in genetic studies of neuropsychiatric disease: multivariate profile-based analysis. Brain Research Bulletin. 83: 177-88. PMID 20433907 DOI: 10.1016/j.brainresbull.2010.04.012  0.52
2010 Salem RM, O'Connor DT, Schork NJ. Curve-based multivariate distance matrix regression analysis: application to genetic association analyses involving repeated measures. Physiological Genomics. 42: 236-47. PMID 20423962 DOI: 10.1152/physiolgenomics.00118.2009  0.52
2010 Levy D, Neuhausen SL, Hunt SC, Kimura M, Hwang SJ, Chen W, Bis JC, Fitzpatrick AL, Smith E, Johnson AD, Gardner JP, Srinivasan SR, Schork N, Rotter JI, Herbig U, et al. Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. Proceedings of the National Academy of Sciences of the United States of America. 107: 9293-8. PMID 20421499 DOI: 10.1073/pnas.0911494107  0.52
2010 Lanktree MB, Hegele RA, Schork NJ, Spence JD. Extremes of unexplained variation as a phenotype: an efficient approach for genome-wide association studies of cardiovascular disease. Circulation. Cardiovascular Genetics. 3: 215-21. PMID 20407100 DOI: 10.1161/CIRCGENETICS.109.934505  0.52
2010 Olincy A, Braff DL, Adler LE, Cadenhead KS, Calkins ME, Dobie DJ, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork NJ, et al. Inhibition of the P50 cerebral evoked response to repeated auditory stimuli: results from the Consortium on Genetics of Schizophrenia. Schizophrenia Research. 119: 175-82. PMID 20382002 DOI: 10.1016/j.schres.2010.03.004  0.52
2010 Jirout ML, Friese RS, Mahapatra NR, Mahata M, Taupenot L, Mahata SK, Kren V, Zídek V, Fischer J, Maatz H, Ziegler MG, Pravenec M, Hubner N, Aitman TJ, Schork NJ, et al. Genetic regulation of catecholamine synthesis, storage and secretion in the spontaneously hypertensive rat. Human Molecular Genetics. 19: 2567-80. PMID 20378607 DOI: 10.1093/hmg/ddq135  0.52
2010 Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Meichle SP, Millard SP, Mintz J, ... ... Schork NJ, et al. Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: data from the COGS study. Psychophysiology. 47: 846-56. PMID 20374545 DOI: 10.1111/j.1469-8986.2010.01004.x  0.52
2010 Schumann CM, Bloss CS, Barnes CC, Wideman GM, Carper RA, Akshoomoff N, Pierce K, Hagler D, Schork N, Lord C, Courchesne E. Longitudinal magnetic resonance imaging study of cortical development through early childhood in autism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4419-27. PMID 20335478 DOI: 10.1523/JNEUROSCI.5714-09.2010  0.52
2010 Schork NJ, Topol EJ. Genotype-based risk and pharmacogenetic sampling in clinical trials. Journal of Biopharmaceutical Statistics. 20: 315-33. PMID 20309761 DOI: 10.1080/10543400903572779  0.52
2010 Torkamani A, Dean B, Schork NJ, Thomas EA. Coexpression network analysis of neural tissue reveals perturbations in developmental processes in schizophrenia. Genome Research. 20: 403-12. PMID 20197298 DOI: 10.1101/gr.101956.109  0.52
2010 Bansal V, Harismendy O, Tewhey R, Murray SS, Schork NJ, Topol EJ, Frazer KA. Accurate detection and genotyping of SNPs utilizing population sequencing data. Genome Research. 20: 537-45. PMID 20150320 DOI: 10.1101/gr.100040.109  0.52
2010 Rimol LM, Agartz I, Djurovic S, Brown AA, Roddey JC, Kähler AK, Mattingsdal M, Athanasiu L, Joyner AH, Schork NJ, Halgren E, Sundet K, Melle I, Dale AM, Andreassen OA, et al. Sex-dependent association of common variants of microcephaly genes with brain structure. Proceedings of the National Academy of Sciences of the United States of America. 107: 384-8. PMID 20080800 DOI: 10.1073/pnas.0908454107  0.52
2010 Lahiry P, Torkamani A, Schork NJ, Hegele RA. Kinase mutations in human disease: interpreting genotype-phenotype relationships. Nature Reviews. Genetics. 11: 60-74. PMID 20019687 DOI: 10.1038/nrg2707  0.52
2010 Chen Y, Wen G, Rao F, Zhang K, Wang L, Rodriguez-Flores JL, Sanchez AP, Mahata M, Taupenot L, Sun P, Mahata SK, Tayo B, Schork NJ, Ziegler MG, Hamilton BA, et al. Human dopamine beta-hydroxylase (DBH) regulatory polymorphism that influences enzymatic activity, autonomic function, and blood pressure. Journal of Hypertension. 28: 76-86. PMID 20009769 DOI: 10.1097/HJH.0b013e328332bc87  0.52
2010 Joo EJ, Greenwood TA, Schork N, McKinney RA, Sadovnick AD, Remick RA, Keck PE, McElroy SL, Kelsoe JR. Suggestive evidence for linkage of ADHD features in bipolar disorder to chromosome 10p14. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 260-8. PMID 19603423 DOI: 10.1002/ajmg.b.31005  0.52
2010 Niculescu AB, Schork NJ, Salomon DR. Mindscape: a convergent perspective on life, mind, consciousness and happiness. Journal of Affective Disorders. 123: 1-8. PMID 19595463 DOI: 10.1016/j.jad.2009.06.022  0.52
2009 Beitelshees AL, Navare H, Wang D, Gong Y, Wessel J, Moss JI, Langaee TY, Cooper-DeHoff RM, Sadee W, Pepine CJ, Schork NJ, Johnson JA. CACNA1C gene polymorphisms, cardiovascular disease outcomes, and treatment response. Circulation. Cardiovascular Genetics. 2: 362-70. PMID 20031608 DOI: 10.1161/CIRCGENETICS.109.857839  0.52
2009 Zhang K, Rao F, Rana BK, Gayen JR, Calegari F, King A, Rosa P, Huttner WB, Stridsberg M, Mahata M, Vaingankar S, Mahboubi V, Salem RM, Rodriguez-Flores JL, Fung MM, ... ... Schork NJ, et al. Autonomic function in hypertension; role of genetic variation at the catecholamine storage vesicle protein chromogranin B. Circulation. Cardiovascular Genetics. 2: 46-56. PMID 20011129 DOI: 10.1161/CIRCGENETICS.108.785659  0.52
2009 Schork NJ, Bansal V. Not so lost in the genetic crowd. Nature Genetics. 41: 1163-4. PMID 19862007 DOI: 10.1038/ng1109-1163  0.52
2009 Dixit A, Yi L, Gowthaman R, Torkamani A, Schork NJ, Verkhivker GM. Sequence and structure signatures of cancer mutation hotspots in protein kinases. Plos One. 4: e7485. PMID 19834613 DOI: 10.1371/journal.pone.0007485  0.52
2009 Mahon PB, Payne JL, MacKinnon DF, Mondimore FM, Goes FS, Schweizer B, Jancic D, Coryell WH, Holmans PA, Shi J, Knowles JA, Scheftner WA, Weissman MM, et al. Genome-wide linkage and follow-up association study of postpartum mood symptoms. The American Journal of Psychiatry. 166: 1229-37. PMID 19755578 DOI: 10.1176/appi.ajp.2009.09030417  0.52
2009 Fung MM, Chen Y, Lipkowitz MS, Salem RM, Bhatnagar V, Mahata M, Nievergelt CM, Rao F, Mahata SK, Schork NJ, Brophy VH, O'Connor DT. Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 24: 3677-86. PMID 19745105 DOI: 10.1093/ndt/gfp471  0.52
2009 Joyner AH, J CR, Bloss CS, Bakken TE, Rimol LM, Melle I, Agartz I, Djurovic S, Topol EJ, Schork NJ, Andreassen OA, Dale AM. A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations. Proceedings of the National Academy of Sciences of the United States of America. 106: 15483-8. PMID 19717458 DOI: 10.1073/pnas.0901866106  0.52
2009 Rana BK, Wessel J, Mahboubi V, Rao F, Haeller J, Gayen JR, Eskin E, Valle AM, Das M, Mahata SK, Taupenot L, Stridsberg M, Talley TT, Ziegler MG, Smith DW, ... Schork NJ, et al. Natural variation within the neuronal nicotinic acetylcholine receptor cluster on human chromosome 15q24: influence on heritable autonomic traits in twin pairs. The Journal of Pharmacology and Experimental Therapeutics. 331: 419-28. PMID 19671882 DOI: 10.1124/jpet.109.157271  0.52
2009 Torkamani A, Schork NJ. Pathway and network analysis with high-density allelic association data. Methods in Molecular Biology (Clifton, N.J.). 563: 289-301. PMID 19597792 DOI: 10.1007/978-1-60761-175-2_16  0.52
2009 Torkamani A, Schork NJ. Identification of rare cancer driver mutations by network reconstruction. Genome Research. 19: 1570-8. PMID 19574499 DOI: 10.1101/gr.092833.109  0.52
2009 Torkamani A, Schork NJ. Prestige centrality-based functional outlier detection in gene expression analysis. Bioinformatics (Oxford, England). 25: 2222-8. PMID 19549629 DOI: 10.1093/bioinformatics/btp388  0.52
2009 Pawlikowska L, Hu D, Huntsman S, Sung A, Chu C, Chen J, Joyner AH, Schork NJ, Hsueh WC, Reiner AP, Psaty BM, Atzmon G, Barzilai N, Cummings SR, Browner WS, et al. Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity. Aging Cell. 8: 460-72. PMID 19489743 DOI: 10.1111/j.1474-9726.2009.00493.x  0.52
2009 Smith EN, Bloss CS, Badner JA, Barrett T, Belmonte PL, Berrettini W, Byerley W, Coryell W, Craig D, Edenberg HJ, Eskin E, Foroud T, Gershon E, Greenwood TA, Hipolito M, ... ... Schork NJ, et al. Genome-wide association study of bipolar disorder in European American and African American individuals. Molecular Psychiatry. 14: 755-63. PMID 19488044 DOI: 10.1038/mp.2009.43  0.52
2009 Schork NJ, Murray SS, Frazer KA, Topol EJ. Common vs. rare allele hypotheses for complex diseases. Current Opinion in Genetics & Development. 19: 212-9. PMID 19481926 DOI: 10.1016/j.gde.2009.04.010  0.52
2009 Harismendy O, Ng PC, Strausberg RL, Wang X, Stockwell TB, Beeson KY, Schork NJ, Murray SS, Topol EJ, Levy S, Frazer KA. Evaluation of next generation sequencing platforms for population targeted sequencing studies. Genome Biology. 10: R32. PMID 19327155 DOI: 10.1186/gb-2009-10-3-r32  0.52
2009 Frazer KA, Murray SS, Schork NJ, Topol EJ. Human genetic variation and its contribution to complex traits. Nature Reviews. Genetics. 10: 241-51. PMID 19293820 DOI: 10.1038/nrg2554  0.52
2009 Schwimmer JB, Celedon MA, Lavine JE, Salem R, Campbell N, Schork NJ, Shiehmorteza M, Yokoo T, Chavez A, Middleton MS, Sirlin CB. Heritability of nonalcoholic fatty liver disease. Gastroenterology. 136: 1585-92. PMID 19208353 DOI: 10.1053/j.gastro.2009.01.050  0.52
2009 Dixit A, Torkamani A, Schork NJ, Verkhivker G. Computational modeling of structurally conserved cancer mutations in the RET and MET kinases: the impact on protein structure, dynamics, and stability. Biophysical Journal. 96: 858-74. PMID 19186126 DOI: 10.1016/j.bpj.2008.10.041  0.52
2009 Ursin G, Lillie EO, Lee E, Cockburn M, Schork NJ, Cozen W, Parisky YR, Hamilton AS, Astrahan MA, Mack T. The relative importance of genetics and environment on mammographic density. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 102-12. PMID 19124487 DOI: 10.1158/1055-9965.EPI-07-2857  0.52
2009 Bhatnagar V, O'Connor DT, Brophy VH, Schork NJ, Richard E, Salem RM, Nievergelt CM, Bakris GL, Middleton JP, Norris KC, Wright J, Hiremath L, Contreras G, Appel LJ, Lipkowitz MS, et al. G-protein-coupled receptor kinase 4 polymorphisms and blood pressure response to metoprolol among African Americans: sex-specificity and interactions. American Journal of Hypertension. 22: 332-8. PMID 19119263 DOI: 10.1038/ajh.2008.341  0.52
2009 Zhang D, Cheng L, Qian Y, Alliey-Rodriguez N, Kelsoe JR, Greenwood T, Nievergelt C, Barrett TB, McKinney R, Schork N, Smith EN, Bloss C, Nurnberger J, Edenberg HJ, Foroud T, et al. Singleton deletions throughout the genome increase risk of bipolar disorder. Molecular Psychiatry. 14: 376-80. PMID 19114987 DOI: 10.1038/mp.2008.144  0.52
2009 Torkamani A, Verkhivker G, Schork NJ. Cancer driver mutations in protein kinase genes. Cancer Letters. 281: 117-27. PMID 19081671 DOI: 10.1016/j.canlet.2008.11.008  0.52
2009 Le-Niculescu H, Patel SD, Bhat M, Kuczenski R, Faraone SV, Tsuang MT, McMahon FJ, Schork NJ, Nurnberger JI, Niculescu AB. Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 155-81. PMID 19025758 DOI: 10.1002/ajmg.b.30887  0.52
2009 Johnson AD, Gong Y, Wang D, Langaee TY, Shin J, Cooper-Dehoff RM, Schork NJ, Binkley P, Pepine CJ, Johnson JA, Sadee W. Promoter polymorphisms in ACE (angiotensin I-converting enzyme) associated with clinical outcomes in hypertension. Clinical Pharmacology and Therapeutics. 85: 36-44. PMID 18946466 DOI: 10.1038/clpt.2008.194  0.52
2008 Rao F, Zhang L, Wessel J, Zhang K, Wen G, Kennedy BP, Rana BK, Das M, Rodriguez-Flores JL, Smith DW, Cadman PE, Salem RM, Mahata SK, Schork NJ, Taupenot L, et al. Adrenergic polymorphism and the human stress response. Annals of the New York Academy of Sciences. 1148: 282-96. PMID 19120120 DOI: 10.1196/annals.1410.085  0.52
2008 Chen Y, Rao F, Rodriguez-Flores JL, Mahata M, Fung MM, Stridsberg M, Vaingankar SM, Wen G, Salem RM, Das M, Cockburn MG, Schork NJ, Ziegler MG, Hamilton BA, Mahata SK, et al. Naturally occurring human genetic variation in the 3'-untranslated region of the secretory protein chromogranin A is associated with autonomic blood pressure regulation and hypertension in a sex-dependent fashion. Journal of the American College of Cardiology. 52: 1468-81. PMID 19017515 DOI: 10.1016/j.jacc.2008.07.047  0.52
2008 Zhou D, Xue J, Lai JC, Schork NJ, White KP, Haddad GG. Mechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch. Plos Genetics. 4: e1000221. PMID 18927626 DOI: 10.1371/journal.pgen.1000221  0.52
2008 Mossé YP, Laudenslager M, Longo L, Cole KA, Wood A, Attiyeh EF, Laquaglia MJ, Sennett R, Lynch JE, Perri P, Laureys G, Speleman F, Kim C, Hou C, Hakonarson H, ... ... Schork NJ, et al. Identification of ALK as a major familial neuroblastoma predisposition gene. Nature. 455: 930-5. PMID 18724359 DOI: 10.1038/nature07261  0.52
2008 Torkamani A, Topol EJ, Schork NJ. Pathway analysis of seven common diseases assessed by genome-wide association. Genomics. 92: 265-72. PMID 18722519 DOI: 10.1016/j.ygeno.2008.07.011  0.52
2008 Turetsky BI, Greenwood TA, Olincy A, Radant AD, Braff DL, Cadenhead KS, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Schork NJ, et al. Abnormal auditory N100 amplitude: a heritable endophenotype in first-degree relatives of schizophrenia probands. Biological Psychiatry. 64: 1051-9. PMID 18701089 DOI: 10.1016/j.biopsych.2008.06.018  0.52
2008 Gerhard T, Gong Y, Beitelshees AL, Mao X, Lobmeyer MT, Cooper-DeHoff RM, Langaee TY, Schork NJ, Shriver MD, Pepine CJ, Johnson JA. Alpha-adducin polymorphism associated with increased risk of adverse cardiovascular outcomes: results from GENEtic Substudy of the INternational VErapamil SR-trandolapril STudy (INVEST-GENES). American Heart Journal. 156: 397-404. PMID 18657677 DOI: 10.1016/j.ahj.2008.03.007  0.52
2008 Pacanowski MA, Gong Y, Cooper-Dehoff RM, Schork NJ, Shriver MD, Langaee TY, Pepine CJ, Johnson JA. beta-adrenergic receptor gene polymorphisms and beta-blocker treatment outcomes in hypertension. Clinical Pharmacology and Therapeutics. 84: 715-21. PMID 18615004 DOI: 10.1038/clpt.2008.139  0.52
2008 Torkamani A, Kannan N, Taylor SS, Schork NJ. Congenital disease SNPs target lineage specific structural elements in protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 105: 9011-6. PMID 18579784 DOI: 10.1073/pnas.0802403105  0.52
2008 Sivagnanam M, Mueller JL, Lee H, Chen Z, Nelson SF, Turner D, Zlotkin SH, Pencharz PB, Ngan BY, Libiger O, Schork NJ, Lavine JE, Taylor S, Newbury RO, Kolodner RD, et al. Identification of EpCAM as the gene for congenital tufting enteropathy. Gastroenterology. 135: 429-37. PMID 18572020 DOI: 10.1053/j.gastro.2008.05.036  0.52
2008 Torkamani A, Schork NJ. Predicting functional regulatory polymorphisms. Bioinformatics (Oxford, England). 24: 1787-92. PMID 18562267 DOI: 10.1093/bioinformatics/btn311  0.52
2008 Chen Y, Rao F, Rodriguez-Flores JL, Mahapatra NR, Mahata M, Wen G, Salem RM, Shih PA, Das M, Schork NJ, Ziegler MG, Hamilton BA, Mahata SK, O'Connor DT. Common genetic variants in the chromogranin A promoter alter autonomic activity and blood pressure. Kidney International. 74: 115-25. PMID 18432188 DOI: 10.1038/ki.2008.113  0.52
2008 Horan WP, Braff DL, Nuechterlein KH, Sugar CA, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Olincy A, Radant AD, ... Schork NJ, et al. Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia. Schizophrenia Research. 103: 218-28. PMID 18406578 DOI: 10.1016/j.schres.2008.02.014  0.52
2008 Schork NJ, Wessel J, Malo N. DNA sequence-based phenotypic association analysis. Advances in Genetics. 60: 195-217. PMID 18358322 DOI: 10.1016/S0065-2660(07)00409-9  0.52
2008 Torkamani A, Schork NJ. Prediction of cancer driver mutations in protein kinases. Cancer Research. 68: 1675-82. PMID 18339846 DOI: 10.1158/0008-5472.CAN-07-5283  0.52
2008 Su CY, Corby PM, Elliot MA, Studen-Pavlovich DA, Ranalli DN, Rosa B, Wessel J, Schork NJ, Hart TC, Bretz WA. Inheritance of occlusal topography: a twin study. European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry. 9: 19-24. PMID 18328234  0.52
2008 Salem RM, Cadman PE, Chen Y, Rao F, Wen G, Hamilton BA, Rana BK, Smith DW, Stridsberg M, Ward HJ, Mahata M, Mahata SK, Bowden DW, Hicks PJ, Freedman BI, ... Schork NJ, et al. Chromogranin A polymorphisms are associated with hypertensive renal disease. Journal of the American Society of Nephrology : Jasn. 19: 600-14. PMID 18235090 DOI: 10.1681/ASN.2007070754  0.52
2008 Fung MM, Nguyen C, Mehtani P, Salem RM, Perez B, Thomas B, Das M, Schork NJ, Mahata SK, Ziegler MG, O'Connor DT. Genetic variation within adrenergic pathways determines in vivo effects of presynaptic stimulation in humans. Circulation. 117: 517-25. PMID 18180394 DOI: 10.1161/CIRCULATIONAHA.107.706317  0.52
2008 Mathews CA, Greenwood T, Wessel J, Azzam A, Garrido H, Chavira DA, Chandavarkar U, Bagnarello M, Stein M, Schork NJ. Evidence for a heritable unidimensional symptom factor underlying obsessionality. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 676-85. PMID 18163383 DOI: 10.1002/ajmg.b.30660  0.52
2008 Evans LM, Akiskal HS, Greenwood TA, Nievergelt CM, Keck PE, McElroy SL, Sadovnick AD, Remick RA, Schork NJ, Kelsoe JR. Suggestive linkage of a chromosomal locus on 18p11 to cyclothymic temperament in bipolar disorder families. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 326-32. PMID 18081158 DOI: 10.1002/ajmg.b.30601  0.52
2008 Zhou D, Wang J, Zapala MA, Xue J, Schork NJ, Haddad GG. Gene expression in mouse brain following chronic hypoxia: role of sarcospan in glial cell death. Physiological Genomics. 32: 370-9. PMID 18056785 DOI: 10.1152/physiolgenomics.00147.2007  0.52
2008 Stein MB, Schork NJ, Gelernter J. Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 312-9. PMID 17460615 DOI: 10.1038/sj.npp.1301422  0.52
2007 Corby PM, Bretz WA, Hart TC, Schork NJ, Wessel J, Lyons-Weiler J, Paster BJ. Heritability of oral microbial species in caries-active and caries-free twins. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 10: 821-8. PMID 18179393 DOI: 10.1375/twin.10.6.821  0.52
2007 Barrett TB, Emberton JE, Nievergelt CM, Liang SG, Hauger RL, Eskin E, Schork NJ, Kelsoe JR. Further evidence for association of GRK3 to bipolar disorder suggests a second disease mutation. Psychiatric Genetics. 17: 315-22. PMID 18075471 DOI: 10.1097/YPG.0b013e3282efeeb4  0.52
2007 Greenwood TA, Braff DL, Light GA, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Mintz J, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, ... ... Schork NJ, et al. Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia. Archives of General Psychiatry. 64: 1242-50. PMID 17984393 DOI: 10.1001/archpsyc.64.11.1242  0.52
2007 Bhatnagar V, O'Connor DT, Schork NJ, Salem RM, Nievergelt CM, Rana BK, Smith DW, Bakris GL, Middleton JP, Norris KC, Wright JT, Cheek D, Hiremath L, Contreras G, Appel LJ, et al. Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the AASK trial. Journal of Hypertension. 25: 2082-92. PMID 17885551 DOI: 10.1097/HJH.0b013e3282b9720e  0.52
2007 Torkamani A, Schork NJ. Accurate prediction of deleterious protein kinase polymorphisms. Bioinformatics (Oxford, England). 23: 2918-25. PMID 17855419 DOI: 10.1093/bioinformatics/btm437  0.52
2007 Mosley CA, Taupenot L, Biswas N, Taulane JP, Olson NH, Vaingankar SM, Wen G, Schork NJ, Ziegler MG, Mahata SK, O'Connor DT. Biogenesis of the secretory granule: chromogranin A coiled-coil structure results in unusual physical properties and suggests a mechanism for granule core condensation. Biochemistry. 46: 10999-1012. PMID 17718510 DOI: 10.1021/bi700704r  0.52
2007 Zhang L, Rao F, Zhang K, Khandrika S, Das M, Vaingankar SM, Bao X, Rana BK, Smith DW, Wessel J, Salem RM, Rodriguez-Flores JL, Mahata SK, Schork NJ, Ziegler MG, et al. Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk. The Journal of Clinical Investigation. 117: 2658-71. PMID 17717598 DOI: 10.1172/JCI31093  0.52
2007 Beitelshees AL, Gong Y, Wang D, Schork NJ, Cooper-Dehoff RM, Langaee TY, Shriver MD, Sadee W, Knot HJ, Pepine CJ, Johnson JA. KCNMB1 genotype influences response to verapamil SR and adverse outcomes in the INternational VErapamil SR/Trandolapril STudy (INVEST). Pharmacogenetics and Genomics. 17: 719-29. PMID 17700361 DOI: 10.1097/FPC.0b013e32810f2e3c  0.52
2007 Rao F, Zhang L, Wessel J, Zhang K, Wen G, Kennedy BP, Rana BK, Das M, Rodriguez-Flores JL, Smith DW, Cadman PE, Salem RM, Mahata SK, Schork NJ, Taupenot L, et al. Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis: discovery of common human genetic variants governing transcription, autonomic activity, and blood pressure in vivo. Circulation. 116: 993-1006. PMID 17698732 DOI: 10.1161/CIRCULATIONAHA.106.682302  0.52
2007 Greenhall JA, Zapala MA, Cáceres M, Libiger O, Barlow C, Schork NJ, Lockhart DJ. Detecting genetic variation in microarray expression data. Genome Research. 17: 1228-35. PMID 17609390 DOI: 10.1101/gr.6307307  0.52
2007 Wen G, Wessel J, Zhou W, Ehret GB, Rao F, Stridsberg M, Mahata SK, Gent PM, Das M, Cooper RS, Chakravarti A, Zhou H, Schork NJ, O'connor DT, Hamilton BA. An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertension. Human Molecular Genetics. 16: 1752-64. PMID 17584765 DOI: 10.1093/hmg/ddm123  0.52
2007 Wessel J, Schork AJ, Tiwari HK, Schork NJ. Powerful designs for genetic association studies that consider twins and sibling pairs with discordant genotypes. Genetic Epidemiology. 31: 789-96. PMID 17549743 DOI: 10.1002/gepi.20241  0.52
2007 Torkamani A, Schork NJ. Distribution analysis of nonsynonymous polymorphisms within the human kinase gene family. Genomics. 90: 49-58. PMID 17498919 DOI: 10.1016/j.ygeno.2007.03.006  0.52
2007 Gong Y, Beitelshees AL, Wessel J, Langaee TY, Schork NJ, Johnson JA. Single nucleotide polymorphism discovery and haplotype analysis of Ca2+-dependent K+ channel beta-1 subunit. Pharmacogenetics and Genomics. 17: 267-75. PMID 17496725 DOI: 10.1097/FPC.0b013e3280105235  0.52
2007 Wessel J, Zapala MA, Schork NJ. Accommodating pathway information in expression quantitative trait locus analysis. Genomics. 90: 132-42. PMID 17493783 DOI: 10.1016/j.ygeno.2007.03.003  0.52
2007 Braff D, Schork NJ, Gottesman II. Endophenotyping schizophrenia. The American Journal of Psychiatry. 164: 705-7. PMID 17475726 DOI: 10.1176/appi.ajp.164.5.705  0.52
2007 Rao F, Wen G, Gayen JR, Das M, Vaingankar SM, Rana BK, Mahata M, Kennedy BP, Salem RM, Stridsberg M, Abel K, Smith DW, Eskin E, Schork NJ, Hamilton BA, et al. Catecholamine release-inhibitory peptide catestatin (chromogranin A(352-372)): naturally occurring amino acid variant Gly364Ser causes profound changes in human autonomic activity and alters risk for hypertension. Circulation. 115: 2271-81. PMID 17438154 DOI: 10.1161/CIRCULATIONAHA.106.628859  0.52
2007 Lillie EO, Mahata M, Khandrika S, Rao F, Bundey RA, Wen G, Chen Y, Taupenot L, Smith DW, Mahata SK, Ziegler MG, Cockburn M, Schork NJ, O'Connor DT. Heredity of endothelin secretion: human twin studies reveal the influence of polymorphism at the chromogranin A locus, a novel determinant of endothelial function. Circulation. 115: 2282-91. PMID 17438153 DOI: 10.1161/CIRCULATIONAHA.106.648345  0.52
2007 Gu CC, Hunt SC, Kardia S, Turner ST, Chakravarti A, Schork N, Olshen R, Curb D, Jaquish C, Boerwinkle E, Rao DC. An investigation of genome-wide associations of hypertension with microsatellite markers in the family blood pressure program (FBPP). Human Genetics. 121: 577-90. PMID 17372766 DOI: 10.1007/s00439-007-0349-8  0.52
2007 Rao F, Wessel J, Wen G, Zhang L, Rana BK, Kennedy BP, Greenwood TA, Salem RM, Chen Y, Khandrika S, Hamilton BA, Smith DW, Holstein-Rathlou NH, Ziegler MG, Schork NJ, et al. Renal albumin excretion: twin studies identify influences of heredity, environment, and adrenergic pathway polymorphism. Hypertension. 49: 1015-31. PMID 17353515 DOI: 10.1161/HYPERTENSIONAHA.106.081679  0.52
2007 Swerdlow NR, Sprock J, Light GA, Cadenhead K, Calkins ME, Dobie DJ, Freedman R, Green MF, Greenwood TA, Gur RE, Mintz J, Olincy A, Nuechterlein KH, Radant AD, Schork NJ, et al. Multi-site studies of acoustic startle and prepulse inhibition in humans: initial experience and methodological considerations based on studies by the Consortium on the Genetics of Schizophrenia. Schizophrenia Research. 92: 237-51. PMID 17346930 DOI: 10.1016/j.schres.2007.01.012  0.52
2007 Hovatta I, Zapala MA, Broide RS, Schadt EE, Libiger O, Schork NJ, Lockhart DJ, Barlow C. DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: implications for eQTL mapping studies. Genome Biology. 8: R25. PMID 17324278 DOI: 10.1186/gb-2007-8-2-r25  0.52
2007 Mathews CA, Nievergelt CM, Azzam A, Garrido H, Chavira DA, Wessel J, Bagnarello M, Reus VI, Schork NJ. Heritability and clinical features of multigenerational families with obsessive-compulsive disorder and hoarding. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 174-82. PMID 17290446 DOI: 10.1002/ajmg.b.30370  0.52
2007 Greenwood TA, Libiger O, Kardia S, Hanis C, Morrison AC, Gu CC, Rice T, Miller M, Turner ST, Myers RH, Grove J, Hsiao CF, Weder AB, Schork NJ. Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the Family Blood Pressure Program. Genetic Epidemiology. 31: 195-210. PMID 17266112 DOI: 10.1002/gepi.20202  0.52
2007 Wessel J, Moratorio G, Rao F, Mahata M, Zhang L, Greene W, Rana BK, Kennedy BP, Khandrika S, Huang P, Lillie EO, Shih PA, Smith DW, Wen G, Hamilton BA, ... ... Schork NJ, et al. C-reactive protein, an 'intermediate phenotype' for inflammation: human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/beta-adrenergic pathway loci. Journal of Hypertension. 25: 329-43. PMID 17211240 DOI: 10.1097/HJH.0b013e328011753e  0.52
2007 Glatt SJ, Chayavichitsilp P, Depp C, Schork NJ, Jeste DV. Successful aging: from phenotype to genotype. Biological Psychiatry. 62: 282-93. PMID 17210144 DOI: 10.1016/j.biopsych.2006.09.015  0.52
2007 Rana BK, Insel PA, Payne SH, Abel K, Beutler E, Ziegler MG, Schork NJ, O'Connor DT. Population-based sample reveals gene-gender interactions in blood pressure in White Americans. Hypertension. 49: 96-106. PMID 17159089 DOI: 10.1161/01.HYP.0000252029.35106.67  0.52
2007 Braff DL, Freedman R, Schork NJ, Gottesman II. Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. Schizophrenia Bulletin. 33: 21-32. PMID 17088422 DOI: 10.1093/schbul/sbl049  0.52
2007 Schork NJ, Greenwood TA, Braff DL. Statistical genetics concepts and approaches in schizophrenia and related neuropsychiatric research. Schizophrenia Bulletin. 33: 95-104. PMID 17035359 DOI: 10.1093/schbul/sbl045  0.52
2007 Calkins ME, Dobie DJ, Cadenhead KS, Olincy A, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork NJ, Seidman LJ, et al. The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration. Schizophrenia Bulletin. 33: 33-48. PMID 17035358 DOI: 10.1093/schbul/sbl044  0.52
2007 Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Light GA, Meichle SP, Mintz J, Nuechterlein KH, Schork NJ, et al. Successful multi-site measurement of antisaccade performance deficits in schizophrenia. Schizophrenia Research. 89: 320-9. PMID 17023145 DOI: 10.1016/j.schres.2006.08.010  0.52
2006 Zapala MA, Schork NJ. Multivariate regression analysis of distance matrices for testing associations between gene expression patterns and related variables. Proceedings of the National Academy of Sciences of the United States of America. 103: 19430-5. PMID 17146048 DOI: 10.1073/pnas.0609333103  0.52
2006 Wessel J, Schork NJ. Generalized genomic distance-based regression methodology for multilocus association analysis. American Journal of Human Genetics. 79: 792-806. PMID 17033957 DOI: 10.1086/508346  0.52
2006 Niculescu AB, Lulow LL, Ogden CA, Le-Niculescu H, Salomon DR, Schork NJ, Caligiuri MP, Lohr JB. PhenoChipping of psychotic disorders: a novel approach for deconstructing and quantitating psychiatric phenotypes. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 653-62. PMID 16838358 DOI: 10.1002/ajmg.b.30404  0.52
2006 Tang H, Jorgenson E, Gadde M, Kardia SL, Rao DC, Zhu X, Schork NJ, Hanis CL, Risch N. Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans. Human Genetics. 119: 624-33. PMID 16738946 DOI: 10.1007/s00439-006-0175-4  0.52
2006 Seasholtz TM, Wessel J, Rao F, Rana BK, Khandrika S, Kennedy BP, Lillie EO, Ziegler MG, Smith DW, Schork NJ, Brown JH, O'Connor DT. Rho kinase polymorphism influences blood pressure and systemic vascular resistance in human twins: role of heredity. Hypertension. 47: 937-47. PMID 16585408 DOI: 10.1161/01.HYP.0000217364.45622.f0  0.52
2006 Greenwood TA, Rao F, Stridsberg M, Mahapatra NR, Mahata M, Lillie EO, Mahata SK, Taupenot L, Schork NJ, O'Connor DT. Pleiotropic effects of novel trans-acting loci influencing human sympathochromaffin secretion. Physiological Genomics. 25: 470-9. PMID 16554546 DOI: 10.1152/physiolgenomics.00295.2005  0.52
2006 Nievergelt CM, Kripke DF, Barrett TB, Burg E, Remick RA, Sadovnick AD, McElroy SL, Keck PE, Schork NJ, Kelsoe JR. Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 234-41. PMID 16528748 DOI: 10.1002/ajmg.b.30252  0.52
2006 Greenwood TA, Schork NJ, Eskin E, Kelsoe JR. Identification of additional variants within the human dopamine transporter gene provides further evidence for an association with bipolar disorder in two independent samples. Molecular Psychiatry. 11: 125-33, 115. PMID 16261167 DOI: 10.1038/sj.mp.4001764  0.52
2005 Schwimmer JB, Behling C, Newbury R, Deutsch R, Nievergelt C, Schork NJ, Lavine JE. Histopathology of pediatric nonalcoholic fatty liver disease. Hepatology (Baltimore, Md.). 42: 641-9. PMID 16116629 DOI: 10.1002/hep.20842  0.52
2005 Bao X, Mills PJ, Rana BK, Dimsdale JE, Schork NJ, Smith DW, Rao F, Milic M, O'Connor DT, Ziegler MG. Interactive effects of common beta2-adrenoceptor haplotypes and age on susceptibility to hypertension and receptor function. Hypertension. 46: 301-7. PMID 16027244 DOI: 10.1161/01.HYP.0000175842.19266.95  0.52
2005 Stein MB, Fallin MD, Schork NJ, Gelernter J. COMT polymorphisms and anxiety-related personality traits. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 2092-102. PMID 15956988 DOI: 10.1038/sj.npp.1300787  0.52
2005 Etzel JP, Rana BK, Wen G, Parmer RJ, Schork NJ, O'Connor DT, Insel PA. Genetic variation at the human alpha2B-adrenergic receptor locus: role in blood pressure variation and yohimbine response. Hypertension. 45: 1207-13. PMID 15920038 DOI: 10.1161/01.HYP.0000166721.42734.49  0.52
2005 King D, Etzel JP, Chopra S, Smith J, Cadman PE, Rao F, Funk SD, Rana BK, Schork NJ, Insel PA, O'Connor DT. Human response to alpha2-adrenergic agonist stimulation studied in an isolated vascular bed in vivo: Biphasic influence of dose, age, gender, and receptor genotype. Clinical Pharmacology and Therapeutics. 77: 388-403. PMID 15900285 DOI: 10.1016/j.clpt.2005.02.008  0.52
2005 Friese RS, Mahboubi P, Mahapatra NR, Mahata SK, Schork NJ, Schmid-Schönbein GW, O'Connor DT. Common genetic mechanisms of blood pressure elevation in two independent rodent models of human essential hypertension. American Journal of Hypertension. 18: 633-52. PMID 15882546 DOI: 10.1016/j.amjhyper.2004.11.037  0.52
2005 An P, Freedman BI, Hanis CL, Chen YD, Weder AB, Schork NJ, Boerwinkle E, Province MA, Hsiung CA, Wu X, Quertermous T, Rao DC. Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis. Diabetes. 54: 909-14. PMID 15734873 DOI: 10.2337/diabetes.54.3.909  0.52
2005 Reiner AP, Ziv E, Lind DL, Nievergelt CM, Schork NJ, Cummings SR, Phong A, Burchard EG, Harris TB, Psaty BM, Kwok PY. Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study. American Journal of Human Genetics. 76: 463-77. PMID 15660291 DOI: 10.1086/428654  0.52
2005 Mustanski BS, Dupree MG, Nievergelt CM, Bocklandt S, Schork NJ, Hamer DH. A genomewide scan of male sexual orientation. Human Genetics. 116: 272-8. PMID 15645181 DOI: 10.1007/s00439-004-1241-4  0.52
2004 Zhang L, Rao F, Wessel J, Kennedy BP, Rana BK, Taupenot L, Lillie EO, Cockburn M, Schork NJ, Ziegler MG, O'Connor DT. Functional allelic heterogeneity and pleiotropy of a repeat polymorphism in tyrosine hydroxylase: prediction of catecholamines and response to stress in twins. Physiological Genomics. 19: 277-91. PMID 15367723 DOI: 10.1152/physiolgenomics.00151.2004  0.52
2004 Ogden CA, Rich ME, Schork NJ, Paulus MP, Geyer MA, Lohr JB, Kuczenski R, Niculescu AB. Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach. Molecular Psychiatry. 9: 1007-29. PMID 15314610 DOI: 10.1038/sj.mp.4001547  0.52
2004 Stein MB, Schork NJ, Gelernter J. A polymorphism of the beta1-adrenergic receptor is associated with low extraversion. Biological Psychiatry. 56: 217-24. PMID 15312808 DOI: 10.1016/j.biopsych.2004.05.020  0.52
2004 Le Corre P, Parmer RJ, Kailasam MT, Kennedy BP, Skaar TP, Ho H, Leverge R, Smith DW, Ziegler MG, Insel PA, Schork NJ, Flockhart DA, O'connor DT. Human sympathetic activation by alpha2-adrenergic blockade with yohimbine: Bimodal, epistatic influence of cytochrome P450-mediated drug metabolism. Clinical Pharmacology and Therapeutics. 76: 139-53. PMID 15289791 DOI: 10.1016/j.clpt.2004.04.010  0.52
2004 Greenwood TA, Rana BK, Schork NJ. Human haplotype block sizes are negatively correlated with recombination rates. Genome Research. 14: 1358-61. PMID 15231751 DOI: 10.1101/gr.1540404  0.52
2004 Fries RS, Mahboubi P, Mahapatra NR, Mahata SK, Schork NJ, Schmid-Schoenbein GW, O'Connor DT. Neuroendocrine transcriptome in genetic hypertension: multiple changes in diverse adrenal physiological systems. Hypertension. 43: 1301-11. PMID 15166183 DOI: 10.1161/01.HYP.0000127708.96195.E6  0.52
2004 Greenwood TA, Cadman PE, Stridsberg M, Nguyen S, Taupenot L, Schork NJ, O'Connor DT. Genome-wide linkage analysis of chromogranin B expression in the CEPH pedigrees: implications for exocytotic sympathochromaffin secretion in humans. Physiological Genomics. 18: 119-27. PMID 15138309 DOI: 10.1152/physiolgenomics.00104.2003  0.52
2004 Conti LH, Jirout M, Breen L, Vanella JJ, Schork NJ, Printz MP. Identification of quantitative trait Loci for anxiety and locomotion phenotypes in rat recombinant inbred strains. Behavior Genetics. 34: 93-103. PMID 14739700 DOI: 10.1023/B:BEGE.0000009479.02183.1f  0.52
2004 Schork NJ, Greenwood TA. Inherent bias toward the null hypothesis in conventional multipoint nonparametric linkage analysis. American Journal of Human Genetics. 74: 306-16. PMID 14732904 DOI: 10.1086/381714  0.52
2003 Jirout M, Krenová D, Kren V, Breen L, Pravenec M, Schork NJ, Printz MP. A new framework marker-based linkage map and SDPs for the rat HXB/BXH strain set. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 537-46. PMID 12925886 DOI: 10.1007/s00335-003-2266-z  0.52
2003 Lee A, Rana BK, Schiffer HH, Schork NJ, Brann MR, Insel PA, Weiner DM. Distribution analysis of nonsynonymous polymorphisms within the G-protein-coupled receptor gene family. Genomics. 81: 245-8. PMID 12659808 DOI: 10.1016/S0888-7543(03)00009-0  0.52
2002 Knöll R, Hoshijima M, Hoffman HM, Person V, Lorenzen-Schmidt I, Bang ML, Hayashi T, Shiga N, Yasukawa H, Schaper W, McKenna W, Yokoyama M, Schork NJ, Omens JH, McCulloch AD, et al. The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy. Cell. 111: 943-55. PMID 12507422 DOI: 10.1016/S0092-8674(02)01226-6  0.52
2002 Kotchen TA, Broeckel U, Grim CE, Hamet P, Jacob H, Kaldunski ML, Kotchen JM, Schork NJ, Tonellato PJ, Cowley AW. Identification of hypertension-related QTLs in African American sib pairs. Hypertension. 40: 634-9. PMID 12411455 DOI: 10.1161/01.HYP.0000036400.79248.22  0.52
2002 Schork NJ, Gardner JP, Zhang L, Fallin D, Thiel B, Jakubowski H, Aviv A. Genomic association/linkage of sodium lithium countertransport in CEPH pedigrees. Hypertension. 40: 619-28. PMID 12411453 DOI: 10.1161/01.HYP.0000037131.41957.A8  0.52
2002 Larribe F, Lessard S, Schork NJ. Gene mapping via the ancestral recombination graph. Theoretical Population Biology. 62: 215-29. PMID 12167358 DOI: 10.1006/tpbi.2002.1601  0.52
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