Lai Y. Leung, Ph.D. - Publications

Affiliations: 
2010 Biomedical Engineering Wayne State University, Detroit, MI, United States 
Area:
Biomedical, Biomechanics

38/65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Li X, Pierre K, Yang Z, Nguyen L, Johnson G, Venetucci J, Torres I, Lucke-Wold B, Shi Y, Boutte A, Shear D, Leung LY, Wang KKW. Blood-Based Brain and Global Biomarker Changes after Combined Hypoxemia and Hemorrhagic Shock in a Rat Model of Penetrating Ballistic-Like Brain Injury. Neurotrauma Reports. 2: 370-380. PMID 34901937 DOI: 10.1089/neur.2021.0006  0.377
2021 Pandya JD, Leung LY, Hwang HM, Yang X, Deng-Bryant Y, Shear DA. Time-course Evaluation of Brain Regional Mitochondrial Bioenergetics in a Preclinical Model of Severe Penetrating Traumatic Brain Injury. Journal of Neurotrauma. PMID 33544034 DOI: 10.1089/neu.2020.7379  0.391
2020 Bailey ZS, Leung LY, Yang X, Cardiff K, Gilsdorf J, Shear D, Kochanek PM. Pre-Hospital Whole Blood Resuscitation Reduces Fluid Requirement While Maintaining Critical Physiology in a Model of Penetrating Traumatic Brain Injury and Hemorrhage: Implications on Resource-Limited Combat Casualty Care. Shock (Augusta, Ga.). PMID 32925600 DOI: 10.1097/Shk.0000000000001662  0.394
2020 Zusman BE, Kochanek PM, Bailey ZS, Leung LY, Vagni VA, Okonkwo DO, Puccio AM, Shutter LA, Janesko-Feldman KL, Gilsdorf JS, Shear DA, Jha RM. Multifaceted Benefit of Whole Blood Versus Lactated Ringer's Resuscitation After Traumatic Brain Injury and Hemorrhagic Shock in Mice. Neurocritical Care. PMID 32886294 DOI: 10.1007/S12028-020-01084-1  0.454
2019 Bailey ZS, Cardiff K, Yang X, Gilsdorf J, Shear D, Rasmussen TE, Leung LY. The Effects of Balloon Occlusion of the Aorta on Cerebral Blood Flow, Intracranial Pressure, and Brain Tissue Oxygen Tension in a Rodent Model of Penetrating Ballistic-Like Brain Injury. Frontiers in Neurology. 10: 1309. PMID 31920932 DOI: 10.3389/Fneur.2019.01309  0.429
2019 Wilfred BS, Madathil SK, Cardiff K, Urankar S, Yang X, Hwang HM, Gilsdorf J, Shear DA, Leung LY. Alterations in peripheral organs following combined hypoxemia and hemorrhagic shock in a rat model of penetrating ballistic-like brain injury. Journal of Neurotrauma. PMID 31595817 DOI: 10.1089/Neu.2019.6570  0.462
2019 Deng-Bryant Y, Leung LY, Madathil S, Flerlage J, Yang F, Yang W, Gilsdorf J, Shear D. Chronic Cognitive Deficits and Associated Histopathology Following Closed-Head Concussive Injury in Rats. Frontiers in Neurology. 10: 699. PMID 31312174 DOI: 10.3389/Fneur.2019.00699  0.385
2019 Pandya JD, Leung LY, Yang X, Flerlage WJ, Gilsdorf JS, Deng-Bryant Y, Shear DA. Comprehensive Profile of Acute Mitochondrial Dysfunction in a Preclinical Model of Severe Penetrating TBI. Frontiers in Neurology. 10: 605. PMID 31244764 DOI: 10.3389/Fneur.2019.00605  0.363
2018 Kassi AAY, Mahavadi AK, Clavijo A, Caliz D, Lee SW, Ahmed AI, Yokobori S, Hu Z, Spurlock MS, Wasserman JM, Rivera KN, Nodal S, Powell HR, Di L, Torres R, ... Leung LY, et al. Enduring Neuroprotective Effect of Subacute Neural Stem Cell Transplantation After Penetrating TBI. Frontiers in Neurology. 9: 1097. PMID 30719019 DOI: 10.3389/Fneur.2018.01097  0.34
2018 Madathil SK, Wilfred BS, Urankar SE, Yang W, Leung LY, Gilsdorf JS, Shear DA. Early Microglial Activation Following Closed-Head Concussive Injury Is Dominated by Pro-Inflammatory M-1 Type. Frontiers in Neurology. 9: 964. PMID 30498469 DOI: 10.3389/Fneur.2018.00964  0.441
2018 Leung LY, Cardiff K, Yang X, Srambical Wilfred B, Gilsdorf J, Shear D. Selective Brain Cooling Reduces Motor Deficits Induced by Combined Traumatic Brain Injury, Hypoxemia and Hemorrhagic Shock. Frontiers in Neurology. 9: 612. PMID 30123177 DOI: 10.3389/Fneur.2018.00612  0.461
2018 Yang Z, Zhu T, Mondello S, Akel M, Wong AT, Kothari IM, Lin F, Shear DA, Gilsdorf J, Leung LY, Bramlett HM, Dixon CE, Dietrich WD, Hayes RL, Povlishock J, et al. Serum-based phospho-neurofilament-heavy protein as theranostic biomarker in three models of traumatic brain injury: an Operation Brain Trauma Therapy (OBTT) study. Journal of Neurotrauma. PMID 29987972 DOI: 10.1089/Neu.2017.5586  0.525
2017 Madathil SK, Deng-Bryant Y, Wilfred BS, Leung LY, Gilsdorf JS, Shear DA. Alterations in brain-derived neurotrophic factor and insulin-like growth factor-1 protein levels after penetrating ballistic-like brain injury in rats. The Journal of Trauma and Acute Care Surgery. 83: S16-S24. PMID 28628600 DOI: 10.1097/Ta.0000000000001471  0.493
2017 Madathil SK, Deng-Bryant Y, Wilfred BS, Leung LY, Gilsdorf JS, Shear DA. Alterations in BDNF and IGF-1 protein levels following penetrating ballistic-like brain injury in rats. The Journal of Trauma and Acute Care Surgery. PMID 28383475 DOI: 10.1097/TA.0000000000001471  0.463
2017 Mountney A, Boutte A, Cartagena CM, Flerlage WJ, Johnson D, Rho C, Lu XM, Yarnell AM, Marcsisin SR, Sousa J, Vuong C, Zottig VE, Leung LY, Deng-Bryant Y, Gilsdorf J, et al. Functional and molecular correlates following single and repeated rat closed-head concussion; indices of vulnerability following brain injury. Journal of Neurotrauma. PMID 28326890 DOI: 10.1089/Neu.2016.4679  0.58
2016 Browning JR, Whiteman AC, Leung LY, Lu XM, Shear DA. Air-puff induced vocalizations: A novel approach to detecting negative affective state following concussion in rats. Journal of Neuroscience Methods. PMID 27984100 DOI: 10.1016/J.Jneumeth.2016.10.017  0.336
2016 Leung LY, Deng-Bryant Y, Cardiff K, Winter M, Tortella F, Shear D. Neurochemical changes following combined hypoxemia and hemorrhagic shock in a rat model of penetrating ballistic-like brain injury: A microdialysis study. The Journal of Trauma and Acute Care Surgery. 81: 860-867. PMID 27769083 DOI: 10.1097/Ta.0000000000001206  0.583
2016 Pandya JD, Sullivan PG, Leung LY, Tortella FC, Shear DA, Deng-Bryant Y. Advanced and High-Throughput Method for Mitochondrial Bioenergetics Evaluation in Neurotrauma. Methods in Molecular Biology (Clifton, N.J.). 1462: 597-610. PMID 27604740 DOI: 10.1007/978-1-4939-3816-2_32  0.37
2016 Deng-Bryant Y, Leung LY, Caudle K, Tortella F, Shear D. Cognitive Evaluation Using Morris Water Maze in Neurotrauma. Methods in Molecular Biology (Clifton, N.J.). 1462: 539-51. PMID 27604737 DOI: 10.1007/978-1-4939-3816-2_29  0.464
2016 Leung LY, Deng-Bryant Y, Shear D, Tortella F. Experimental Models Combining TBI, Hemorrhagic Shock, and Hypoxemia. Methods in Molecular Biology (Clifton, N.J.). 1462: 445-58. PMID 27604733 DOI: 10.1007/978-1-4939-3816-2_25  0.531
2016 Deng-Bryant Y, Readnower R, Leung LY, Tortella F, Shear D. Methods of Drug Delivery in Neurotrauma. Methods in Molecular Biology (Clifton, N.J.). 1462: 89-100. PMID 27604714 DOI: 10.1007/978-1-4939-3816-2_6  0.32
2015 Lu XM, Shear DA, Deng-Bryant Y, Leung LY, Wei G, Chen Z, Tortella FC. Comprehensive Evaluation of Neuroprotection Achieved by Extended Selective Brain Cooling Therapy in a Rat Model of Penetrating Ballistic-Like Brain Injury. Therapeutic Hypothermia and Temperature Management. PMID 26684246 DOI: 10.1089/Ther.2015.0017  0.573
2015 Leung LY, Deng-Bryant Y, Shear D, Tortella F. Combined hypoxemic and hypotensive insults altered physiological responses and neurofunction in a severity-dependent manner following penetrating ballistic-like brain injury in rats. The Journal of Trauma and Acute Care Surgery. 79: S130-8. PMID 26406425 DOI: 10.1097/Ta.0000000000000785  0.602
2015 Tortella FC, Leung LY. Traumatic Brain Injury and Polytrauma in Theaters of Combat: The Case for Neurotrauma Resuscitation? Shock (Augusta, Ga.). 44: 17-26. PMID 25895144 DOI: 10.1097/Shk.0000000000000380  0.546
2015 Lu XC, Shear DA, Graham PB, Bridson GW, Uttamsingh V, Chen Z, Leung LY, Tortella FC. Dual Therapeutic Effects of C-10068, a Dextromethorphan Derivative, Against Post-Traumatic Nonconvulsive Seizures and Neuroinflammation in a Rat Model of Penetrating Ballistic-Like Brain Injury. Journal of Neurotrauma. PMID 25794265 DOI: 10.1089/Neu.2014.3766  0.425
2015 Gajavelli S, Kentaro S, Diaz J, Yokobori S, Spurlock M, Diaz D, Jackson C, Wick A, Zhao W, Leung LY, Shear D, Tortella F, Bullock MR. Glucose and oxygen metabolism after penetrating ballistic-like brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 773-80. PMID 25669903 DOI: 10.1038/Jcbfm.2014.243  0.482
2015 Deng-Bryant Y, Readnower RD, Leung LY, Cunningham TL, Shear DA, Tortella FC. Treatment with amnion-derived cellular cytokine solution (ACCS) induces persistent motor improvement and ameliorates neuroinflammation in a rat model of penetrating ballistic-like brain injury. Restorative Neurology and Neuroscience. 33: 189-203. PMID 25588460 DOI: 10.3233/Rnn-140455  0.522
2014 Leung LY, Larimore Z, Holmes L, Cartagena C, Mountney A, Deng-Bryant Y, Schmid K, Shear D, Tortella F. The WRAIR projectile concussive impact model of mild traumatic brain injury: re-design, testing and preclinical validation. Annals of Biomedical Engineering. 42: 1618-30. PMID 24756867 DOI: 10.1007/S10439-014-1014-8  0.459
2013 Leung LY, Wei G, Shear DA, Tortella FC. The acute effects of hemorrhagic shock on cerebral blood flow, brain tissue oxygen tension, and spreading depolarization following penetrating ballistic-like brain injury. Journal of Neurotrauma. 30: 1288-98. PMID 23461630 DOI: 10.1089/Neu.2012.2715  0.53
2013 Lu XC, Mountney A, Chen Z, Wei G, Cao Y, Leung LY, Khatri V, Cunningham T, Tortella FC. Similarities and differences of acute nonconvulsive seizures and other epileptic activities following penetrating and ischemic brain injuries in rats. Journal of Neurotrauma. 30: 580-90. PMID 23234254 DOI: 10.1089/Neu.2012.2641  0.505
2013 Mountney A, Leung LY, Pedersen R, Shear D, Tortella F. Longitudinal assessment of gait abnormalities following penetrating ballistic-like brain injury in rats. Journal of Neuroscience Methods. 212: 1-16. PMID 22981945 DOI: 10.1016/J.Jneumeth.2012.08.025  0.554
2012 Kane MJ, Angoa-Pérez M, Francescutti DM, Sykes CE, Briggs DI, Leung LY, VandeVord PJ, Kuhn DM. Altered gene expression in cultured microglia in response to simulated blast overpressure: possible role of pulse duration. Neuroscience Letters. 522: 47-51. PMID 22698585 DOI: 10.1016/J.Neulet.2012.06.012  0.49
2012 Chen Z, Leung LY, Mountney A, Liao Z, Yang W, Lu XC, Dave J, Deng-Bryant Y, Wei G, Schmid K, Shear DA, Tortella FC. A novel animal model of closed-head concussive-induced mild traumatic brain injury: development, implementation, and characterization. Journal of Neurotrauma. 29: 268-80. PMID 21988140 DOI: 10.1089/Neu.2011.2057  0.59
2012 Murakami Y, Wei G, Yang X, Lu XC, Leung LY, Shear DA, Tortella FC. Brain oxygen tension monitoring following penetrating ballistic-like brain injury in rats. Journal of Neuroscience Methods. 203: 115-21. PMID 21983109 DOI: 10.1016/J.Jneumeth.2011.09.025  0.558
2008 Leung LY, VandeVord PJ, Dal Cengio AL, Bir C, Yang KH, King AI. Blast related neurotrauma: a review of cellular injury. Molecular & Cellular Biomechanics : McB. 5: 155-68. PMID 18751525  0.601
2008 Vandevord PJ, Leung LY, Hardy W, Mason M, Yang KH, King AI. Up-regulation of reactivity and survival genes in astrocytes after exposure to short duration overpressure. Neuroscience Letters. 434: 247-52. PMID 18342445 DOI: 10.1016/J.Neulet.2008.01.056  0.588
2006 Jin X, Lee JB, Leung LY, Zhang L, Yang KH, King AI. Biomechanical response of the bovine pia-arachnoid complex to tensile loading at varying strain-rates. Stapp Car Crash Journal. 50: 637-49. PMID 17311181 DOI: 10.4271/2006-22-0025  0.532
2006 Leung LY, Tong KY, Zhang SM, Zeng XH, Zhang KP, Zheng XX. Neurochemical effects of exercise and neuromuscular electrical stimulation on brain after stroke: A microdialysis study using rat model Neuroscience Letters. 397: 135-139. PMID 16384643 DOI: 10.1016/J.Neulet.2005.12.006  0.32
Low-probability matches (unlikely to be authored by this person)
2022 Ronaldi AE, Lauria AL, Paterson JE, Kersey AJ, Leung LY, Burmeister DM, Baer DG, White PW, Rasmussen TE, White JM. Targeted Regional Optimization in Action: Dose-Dependent end Organ Ischemic Injury with Partial Aortic Occlusion in The Setting of Ongoing Liver Hemorrhage. Shock (Augusta, Ga.). PMID 35234207 DOI: 10.1097/SHK.0000000000001922  0.2
2014 Krishnan V, Leung LY, Caplan LR. A neurologist's approach to delirium: diagnosis and management of toxic metabolic encephalopathies. European Journal of Internal Medicine. 25: 112-6. PMID 24332366 DOI: 10.1016/J.Ejim.2013.11.010  0.184
2007 Leung LY, VandeVord PJ, Hardy W, De Guzman R, Yang KH, King AI. Effects of short duration overpressure on astrocytes: An in vitro study Proceedings of the Asme Summer Bioengineering Conference 2007, Sbc 2007. 597-598.  0.146
2022 Polcz JE, Ronaldi AE, Madurska M, Bedocs P, Leung LY, Burmeister DM, White PW, Rasmussen TE, White JM. Next-Generation REBOA (Resuscitative Endovascular Balloon Occlusion of the Aorta) Device Precisely Achieves Targeted Regional Optimization in a Porcine Model of Hemorrhagic Shock. The Journal of Surgical Research. 280: 1-9. PMID 35939866 DOI: 10.1016/j.jss.2022.06.007  0.127
2021 Madurska MJ, Abdou H, Leung LY, Richmond MJ, Elansary NN, Scalea TM, Hu P, Morrison JJ. The Cardiac Physiology Underpinning Exsanguination Cardiac Arrest: Targets for Endovascular Resuscitation. Shock (Augusta, Ga.). 55: 83-89. PMID 33337788 DOI: 10.1097/SHK.0000000000001607  0.113
2013 Leung LY, Albright KC, Boehme AK, Tarsia J, Shah KR, Siegler JE, Jones EM, Pletsch GR, Beasley TM, Martin-Schild S. Short-term bleeding events observed with clopidogrel loading in acute ischemic stroke patients. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 22: 1184-9. PMID 23541421 DOI: 10.1016/j.jstrokecerebrovasdis.2013.03.001  0.107
2020 White JM, Ronaldi AE, Polcz JE, Spreadborough P, Madurska M, Mares JA, Leung LY, Rasmussen TE. A New Pressure-Regulated, Partial REBOA Device Achieves Targeted Distal Perfusion. The Journal of Surgical Research. 256: 171-179. PMID 32707400 DOI: 10.1016/j.jss.2020.06.042  0.099
2014 Leung LY, Brett M, Zurawski J, Kumar S. Recurrent aseptic meningitis with reversible cerebral vasoconstriction. Journal of the Neurological Sciences. 339: 239-40. PMID 24607332 DOI: 10.1016/j.jns.2014.02.015  0.095
2013 Rosen DB, Harrington KH, Cordeiro JA, Leung LY, Putta S, Lacayo N, Laszlo GS, Gudgeon CJ, Hogge DE, Hawtin RE, Cesano A, Walter RB. AKT signaling as a novel factor associated with in vitro resistance of human AML to gemtuzumab ozogamicin. Plos One. 8: e53518. PMID 23320091 DOI: 10.1371/Journal.Pone.0053518  0.095
2009 Kwong AK, Ng AH, Leung LY, Man AK, Woo NY. Effect of extracellular osmolality and ionic levels on pituitary prolactin release in euryhaline silver sea bream (Sparus sarba). General and Comparative Endocrinology. 160: 67-75. PMID 19027016 DOI: 10.1016/j.ygcen.2008.10.024  0.092
2006 Leung LY, Lim HK, Abell MW, Zimmerman JJ. Pharmacokinetics and metabolic disposition of sirolimus in healthy male volunteers after a single oral dose. Therapeutic Drug Monitoring. 28: 51-61. PMID 16418694 DOI: 10.1097/01.ftd.0000179838.33020.34  0.078
2010 Leung LY, Woo NY. Effects of growth hormone, insulin-like growth factor I, triiodothyronine, thyroxine, and cortisol on gene expression of carbohydrate metabolic enzymes in sea bream hepatocytes. Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 157: 272-82. PMID 20647047 DOI: 10.1016/j.cbpa.2010.07.010  0.077
2014 Rosen DB, Leung LY, Louie B, Cordeiro JA, Conroy A, Shapira I, Fields SZ, Cesano A, Hawtin RE. Quantitative measurement of alterations in DNA damage repair (DDR) pathways using single cell network profiling (SCNP). Journal of Translational Medicine. 12: 184. PMID 24965603 DOI: 10.1186/1479-5876-12-184  0.068
2007 Leung LY, Tian D, Brangwynne CP, Weitz DA, Tschumperlin DJ. A new microrheometric approach reveals individual and cooperative roles for TGF-beta1 and IL-1beta in fibroblast-mediated stiffening of collagen gels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2064-73. PMID 17341683 DOI: 10.1096/Fj.06-7510Com  0.068
2012 Leung LY, Woo NY. Influence of dietary carbohydrate level on endocrine status and hepatic carbohydrate metabolism in the marine fish Sparus sarba. Fish Physiology and Biochemistry. 38: 543-54. PMID 21701819 DOI: 10.1007/s10695-011-9534-8  0.068
2008 Leung LY, Kwong AK, Man AK, Woo NY. Direct actions of cortisol, thyroxine and growth hormone on IGF-I mRNA expression in sea bream hepatocytes. Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 151: 705-10. PMID 18790068 DOI: 10.1016/j.cbpa.2008.08.023  0.067
2011 Chan DW, Liu VW, Leung LY, Yao KM, Chan KK, Cheung AN, Ngan HY. Zic2 synergistically enhances Hedgehog signalling through nuclear retention of Gli1 in cervical cancer cells. The Journal of Pathology. 225: 525-34. PMID 21661123 DOI: 10.1002/path.2901  0.066
2016 Leung LY, Caplan LR. Factors Associated with Delay in Presentation to the Hospital for Young Adults with Ischemic Stroke Cerebrovascular Diseases. 10-14. DOI: 10.1159/000443242  0.066
2014 Bernson-Leung ME, Leung LY, Kumar S. Synthetic cannabis and acute ischemic stroke. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 23: 1239-41. PMID 24119618 DOI: 10.1016/j.jstrokecerebrovasdis.2013.07.030  0.063
2012 Post ES, Grambsch A, Weaver C, Morefield P, Huang J, Leung LY, Nolte CG, Adams P, Liang XZ, Zhu JH, Mahoney H. Variation in estimated ozone-related health impacts of climate change due to modeling choices and assumptions. Environmental Health Perspectives. 120: 1559-64. PMID 22796531 DOI: 10.1289/Ehp.1104271  0.054
2012 Chan CP, Jiang HL, Leung LY, Wan WM, Cheng NM, Ip WS, Cheung KY, Chan RW, Wong LK, Graham CA, Renneberg R, Rainer TH. Multiple atherosclerosis-related biomarkers associated with short- and long-term mortality after stroke. Clinical Biochemistry. 45: 1308-15. PMID 22728010 DOI: 10.1016/J.Clinbiochem.2012.06.014  0.051
1998 Schibler KR, Osborne KA, Leung LY, Le TV, Baker SI, Thompson DD. A randomized, placebo-controlled trial of granulocyte colony-stimulating factor administration to newborn infants with neutropenia and clinical signs of early-onset sepsis. Pediatrics. 102: 6-13. PMID 9651406 DOI: 10.1542/peds.102.1.6  0.041
1991 Lin RQ, Kreiss H, Kuang WJ, Leung LY. A study of long-term climate change in a simple seasonal nonlinear climate model Climate Dynamics. 6: 35-41. DOI: 10.1007/BF00210580  0.039
2014 Leung LY, Chan CP, Leung YK, Jiang HL, Abrigo JM, Wang de F, Chung JS, Rainer TH, Graham CA. Comparison of miR-124-3p and miR-16 for early diagnosis of hemorrhagic and ischemic stroke. Clinica Chimica Acta; International Journal of Clinical Chemistry. 433: 139-44. PMID 24650689 DOI: 10.1016/j.cca.2014.03.007  0.036
2007 Tagaris E, Liao KJ, Manomaiphiboon K, Russell AG, Woo JH, He S, Amar P, Leung LY. Global climate change impacts on air quality in North America 87th Ams Annual Meeting 0.029
2012 Creed PA, Hood M, Leung LY. The Relationship Between Control, Job Seeking, and Well-Being in Unemployed People Journal of Applied Social Psychology. 42: 689-701. DOI: 10.1111/j.1559-1816.2011.00798.x  0.01
2008 Wang M, Liu Y, Au CL, Lai PK, Leung LY, Chua BH. Deformation and fracture of bone analogue biomaterials having different polymer matrices Advanced Materials Research. 47: 1391-1394.  0.01
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