123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Kochanek PM, Dixon CE, Mondello S, Wang KKK, Lafrenaye A, Bramlett HM, Dietrich WD, Hayes RL, Shear DA, Gilsdorf JS, Catania M, Poloyac SM, Empey PE, Jackson TC, Povlishock JT. Multi-Center Pre-clinical Consortia to Enhance Translation of Therapies and Biomarkers for Traumatic Brain Injury: Operation Brain Trauma Therapy and Beyond. Frontiers in Neurology. 9: 640. PMID 30131759 DOI: 10.3389/fneur.2018.00640  1
2018 Yang Z, Zhu T, Mondello S, Akel M, Wong AT, Kothari IM, Lin F, Shear DA, Gilsdorf J, Leung LY, Bramlett HM, Dixon CE, Dietrich WD, Hayes RL, Povlishock J, et al. Serum-based phospho-neurofilament-heavy protein as theranostic biomarker in three models of traumatic brain injury: an Operation Brain Trauma Therapy (OBTT) study. Journal of Neurotrauma. PMID 29987972 DOI: 10.1089/neu.2017.5586  1
2018 DeWitt D, Hawkins BE, Dixon CE, Kochanek PM, Armstead WM, Bass C', Bramlett HM, Büki A, Dietrich WD, Ferguson AR, Hall ED, Hayes RL, Hinds Ii CSR, LaPlaca M, Long J, et al. Preclinical Testing of Therapies for Traumatic Brain Injury. Journal of Neurotrauma. PMID 29756522 DOI: 10.1089/neu.2018.5778  1
2018 Kochanek PM, Bramlett HM, Dixon CE, Dietrich WD, Mondello S, Wang KKW, Hayes RL, Lafrenaye A, Povlishock JT, Tortella FC, Poloyac SM, Empey P, Shear DA. Operation Brain Trauma Therapy: 2016 Update. Military Medicine. 183: 303-312. PMID 29635589 DOI: 10.1093/milmed/usx184  1
2017 Jayaraman SP, Anand RJ, DeAntonio JH, Mangino M, Aboutanos MB, Kasirajan V, Ivatury R, Valadka AB, Glushakova O, Hayes RL, Bachmann LM, Brophy GM, Contaifer D, Warncke UO, Brophy DF, et al. Metabolomics and Precision Medicine in Trauma: The State of the Field. Shock (Augusta, Ga.). PMID 29280924 DOI: 10.1097/SHK.0000000000001093  0.36
2017 Kobeissy FH, Liu MC, Yang Z, Zhang Z, Zheng W, Glushakova O, Mondello S, Anagli J, Hayes RL, Wang KKW. Erratum to: Degradation of βII-Spectrin Protein by Calpain-2 and Caspase-3 Under Neurotoxic and Traumatic Brain Injury Conditions. Molecular Neurobiology. PMID 28975597 DOI: 10.1007/s12035-017-0764-3  1
2017 Papa L, Robicsek SA, Brophy GM, Wang KKW, Hannay HJ, Heaton SC, Schmalfuss I, Gabrielli A, Hayes RL, Robertson CS. Temporal Profile of Microtubule Associated Protein (MAP-2) - A Novel Indicator of Diffuse Brain Injury Severity and Early Mortality after Brain Trauma. Journal of Neurotrauma. PMID 28895474 DOI: 10.1089/neu.2017.4994  0.52
2017 Glushakova O, Glushakov AO, Borlongan C, Valadka A, Hayes RL, Glushakov AV. Role of Caspase-3-mediated Apoptosis in Chronic Caspase-3-cleaved Tau Accumulation and Blood-brain Barrier Damage in the Corpus Callosum after Traumatic Brain Injury in Rats. Journal of Neurotrauma. PMID 28637381 DOI: 10.1089/neu.2017.4999  0.36
2017 Yang Z, Bramlett HM, Moghieb A, Yu D, Wang P, Lin F, Bauer C, Selig TM, Jaalouk E, Weissman AS, Rathore DS, Romo P, Zhang Z, Hayes RL, Wang MY, et al. Temporal Profile and Severity Correlation of a Panel of Rat Spinal Cord Injury Protein Biomarkers. Molecular Neurobiology. PMID 28290147 DOI: 10.1007/s12035-017-0424-7  0.44
2016 Kobeissy FH, Guingab-Cagmat JD, Zhang Z, Moghieb A, Glushakova OY, Mondello S, Boutté AM, Anagli J, Rubenstein R, Bahmad H, Wagner AK, Hayes RL, Wang KK. Neuroproteomics and Systems Biology Approach to Identify Temporal Biomarker Changes Post Experimental Traumatic Brain Injury in Rats. Frontiers in Neurology. 7: 198. PMID 27920753 DOI: 10.3389/fneur.2016.00198  1
2016 Mondello S, Kobeissy F, Vestri A, Hayes RL, Kochanek PM, Berger RP. Serum Concentrations of Ubiquitin C-Terminal Hydrolase-L1 and Glial Fibrillary Acidic Protein after Pediatric Traumatic Brain Injury. Scientific Reports. 6: 28203. PMID 27319802 DOI: 10.1038/srep28203  1
2016 Ren C, Kobeissy F, Alawieh A, Li N, Li N, Zibara K, Zoltewicz S, Guingab-Cagmat J, Larner SF, Ding Y, Hayes RL, Ji X, Mondello S. Assessment of Serum UCH-L1 and GFAP in Acute Stroke Patients. Scientific Reports. 6: 24588. PMID 27074724 DOI: 10.1038/srep24588  1
2016 Fink EL, Berger RP, Clark RS, Watson RS, Angus DC, Panigrahy A, Richichi R, Callaway CW, Bell MJ, Mondello S, Hayes RL, Kochanek PM. Exploratory Study of Serum Ubiquitin Carboxyl-Terminal Esterase L1 and Glial Fibrillary Acidic Protein for Outcome Prognostication after Pediatric Cardiac Arrest. Resuscitation. PMID 26855294 DOI: 10.1016/j.resuscitation.2016.01.024  1
2015 Mondello S, Shear DA, Bramlett HM, Dixon CE, Schmid Maj KE, Dietrich WD, Wang KK, Hayes RL, Glushakova O, Catania M, Richieri S, Povlishock J, Tortella FC, Kochanek PM. Insight into Preclinical Models of Traumatic Brain Injury Using Circulating Brain Damage Biomarkers: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671651 DOI: 10.1089/neu.2015.4132  0.6
2015 Browning M, Shear DA, Bramlett HM, Dixon CE, Mondello S, Schmid Maj KE, Poloyac SM, Dietrich WD, Hayes RL, Wang KK, Povlishock J, Tortella FC, Kochanek PM. Levetiracetam Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671550 DOI: 10.1089/neu.2015.4131  0.6
2015 Kochanek PM, Bramlett HM, Shear DA, Dixon CE, Mondello S, Dietrich WD, Hayes RL, Wang KK, Poloyac SM, Empey P, Povlishock J, Mountney A, Browning M, Deng-Bryant Y, Yan HQ, et al. Synthesis of Findings, Current Investigations, and Future Directions: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671284 DOI: 10.1089/neu.2015.4133  0.6
2015 Dixon CE, Bramlett HM, Dietrich WD, Shear DA, Yan HQ, Deng-Bryant Y, Mondello S, Wang KK, Hayes RL, Empey P, Povlishock J, Tortella FC, Kochanek PM. Cyclosporine Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671075 DOI: 10.1089/neu.2015.4122  0.6
2015 Shear DA, Bramlett HM, Dixon CE, Dietrich WD, Deng-Bryant Y, Schmid Maj KE, Mondello S, Wang KK, Hayes RL, Povlishock J, Kochanek PM, Tortella FC. Nicotinamide Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26670792 DOI: 10.1089/neu.2015.4115  0.6
2015 Bramlett HM, Dietrich WD, Dixon CE, Shear DA, Schmid Maj KE, Mondello S, Wang KK, Hayes RL, Povlishock J, Tortella FC, Kochanek PM. Erythropoietin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26670694 DOI: 10.1089/neu.2015.4116  0.6
2015 Mountney A, Bramlett HM, Dixon CE, Mondello S, Dietrich WD, Wang KK, Caudle KL, Empey P, Poloyac SM, Hayes RL, Povlishock J, Tortella FC, Kochanek PM, Shear DA. Simvastatin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26541177 DOI: 10.1089/neu.2015.4130  0.6
2015 Welch RD, Ayaz SI, Lewis LM, Unden J, Chen JY, Mika VH, Saville B, Tyndall JA, Nash M, Buki A, Barzo P, Hack D, Tortella FC, Schmid K, Hayes RL, et al. Ability of Serum Glial Fibrillary Acidic Protein, Ubiquitin C-Terminal Hydrolase-L1, and S100B to Differentiate Normal and Abnormal Head Computed Tomography Findings in Patients with Suspected Mild or Moderate Traumatic Brain Injury. Journal of Neurotrauma. PMID 26467555 DOI: 10.1089/neu.2015.4149  1
2015 Kochanek PM, Bramlett HM, Dixon CE, Shear DA, Dietrich WD, Schmid K, Mondello S, Wang KK, Hayes RL, Povlishock J, Tortella St FC. Operation Brain Trauma Therapy: Approach to Modeling, Therapy Evaluation, Drug Selection, and Biomarker Assessments, for a Multi-Center Pre-Clinical Drug Screening Consortium for Acute Therapies in Severe Traumatic Brain Injury. Journal of Neurotrauma. PMID 26439468 DOI: 10.1089/neu.2015.4113  0.6
2015 Huang XJ, Glushakova O, Mondello S, Van K, Hayes RL, Lyeth BG. Acute Temporal Profiles of Serum Levels of UCH-L1 and GFAP and Relationships to Neuronal and Astroglial Pathology following Traumatic Brain Injury in Rats. Journal of Neurotrauma. PMID 25763798 DOI: 10.1089/neu.2015.3873  1
2015 Tóth A, Schmalfuss I, Heaton SC, Gabrielli A, Hannay HJ, Papa L, Brophy GM, Wang KK, Büki A, Schwarcz A, Hayes RL, Robertson CS, Robicsek SA. Lateral Ventricle Volume Asymmetry Predicts Midline Shift in Severe Traumatic Brain Injury. Journal of Neurotrauma. PMID 25752227 DOI: 10.1089/neu.2014.3696  0.6
2015 Mondello S, Hayes RL. Biomarkers. Handbook of Clinical Neurology. 127: 245-65. PMID 25702221 DOI: 10.1016/B978-0-444-52892-6.00016-7  1
2015 Buki A, Kovacs N, Czeiter E, Schmid K, Berger RP, Kobeissy F, Italiano D, Hayes RL, Tortella FC, Mezosi E, Schwarcz A, Toth A, Nemes O, Mondello S. Minor and repetitive head injury. Advances and Technical Standards in Neurosurgery. 42: 147-92. PMID 25411149 DOI: 10.1007/978-3-319-09066-5_8  0.6
2015 Papa L, Robertson CS, Wang KK, Brophy GM, Hannay HJ, Heaton S, Schmalfuss I, Gabrielli A, Hayes RL, Robicsek SA. Biomarkers improve clinical outcome predictors of mortality following non-penetrating severe traumatic brain injury. Neurocritical Care. 22: 52-64. PMID 25052159 DOI: 10.1007/s12028-014-0028-2  0.6
2015 Yokobori S, Zhang Z, Moghieb A, Mondello S, Gajavelli S, Dietrich WD, Bramlett H, Hayes RL, Wang M, Wang KK, Bullock MR. Acute diagnostic biomarkers for spinal cord injury: review of the literature and preliminary research report. World Neurosurgery. 83: 867-78. PMID 23524031 DOI: 10.1016/j.wneu.2013.03.012  1
2014 Douglas-Escobar MV, Heaton SC, Bennett J, Young LJ, Glushakova O, Xu X, Barbeau DY, Rossignol C, Miller C, Old Crow AM, Hayes RL, Weiss MD. UCH-L1 and GFAP Serum Levels in Neonates with Hypoxic-Ischemic Encephalopathy: A Single Center Pilot Study. Frontiers in Neurology. 5: 273. PMID 25566179 DOI: 10.3389/fneur.2014.00273  0.6
2014 Kobeissy FH, Liu MC, Yang Z, Zhang Z, Zheng W, Glushakova O, Mondello S, Anagli J, Hayes RL, Wang KK. Degradation of βII-Spectrin Protein by Calpain-2 and Caspase-3 Under Neurotoxic and Traumatic Brain Injury Conditions. Molecular Neurobiology. PMID 25270371 DOI: 10.1007/s12035-014-8898-z  0.6
2014 Papa L, Silvestri S, Brophy GM, Giordano P, Falk JL, Braga CF, Tan CN, Ameli NJ, Demery JA, Dixit NK, Mendes ME, Hayes RL, Wang KK, Robertson CS. GFAP out-performs S100β in detecting traumatic intracranial lesions on computed tomography in trauma patients with mild traumatic brain injury and those with extracranial lesions. Journal of Neurotrauma. 31: 1815-22. PMID 24903744 DOI: 10.1089/neu.2013.3245  0.6
2014 Ren C, Guingab-Cagmat J, Kobeissy F, Zoltewicz S, Mondello S, Gao M, Hafeez A, Li N, Geng X, Larner SF, Anagli J, Hayes RL, Ji X, Ding Y. A neuroproteomic and systems biology analysis of rat brain post intracerebral hemorrhagic stroke. Brain Research Bulletin. 102: 46-56. PMID 24583080 DOI: 10.1016/j.brainresbull.2014.02.005  0.6
2014 Glushakova OY, Johnson D, Hayes RL. Delayed increases in microvascular pathology after experimental traumatic brain injury are associated with prolonged inflammation, blood-brain barrier disruption, and progressive white matter damage. Journal of Neurotrauma. 31: 1180-93. PMID 24564198 DOI: 10.1089/neu.2013.3080  0.6
2014 Mannix R, Eisenberg M, Berry M, Meehan WP, Hayes RL. Serum biomarkers predict acute symptom burden in children after concussion: a preliminary study. Journal of Neurotrauma. 31: 1072-5. PMID 24494742 DOI: 10.1089/neu.2013.3265  0.6
2013 Ren C, Zoltewicz S, Guingab-Cagmat J, Anagli J, Gao M, Hafeez A, Li N, Cao J, Geng X, Kobeissy F, Mondello S, Larner SF, Hayes RL, Ji X, Ding Y. Different expression of ubiquitin C-terminal hydrolase-L1 and αII-spectrin in ischemic and hemorrhagic stroke: Potential biomarkers in diagnosis. Brain Research. 1540: 84-91. PMID 24140110 DOI: 10.1016/j.brainres.2013.09.051  0.6
2013 Prima V, Serebruany VL, Svetlov A, Hayes RL, Svetlov SI. Impact of moderate blast exposures on thrombin biomarkers assessed by calibrated automated thrombography in rats. Journal of Neurotrauma. 30: 1881-7. PMID 23805797 DOI: 10.1089/neu.2012.2758  0.6
2013 Tate CM, Wang KK, Eonta S, Zhang Y, Carr W, Tortella FC, Hayes RL, Kamimori GH. Serum brain biomarker level, neurocognitive performance, and self-reported symptom changes in soldiers repeatedly exposed to low-level blast: a breacher pilot study. Journal of Neurotrauma. 30: 1620-30. PMID 23687938 DOI: 10.1089/neu.2012.2683  0.6
2013 Yokobori S, Bullock R, Gajavelli S, Burks S, Mondello S, Mo J, Wang KK, Hayes RL, Bramlett H, Dietrich D. Preoperative-induced mild hypothermia attenuates neuronal damage in a rat subdural hematoma model. Acta Neurochirurgica. Supplement. 118: 77-81. PMID 23564108 DOI: 10.1007/978-3-7091-1434-6_13  0.6
2013 Zoltewicz JS, Mondello S, Yang B, Newsom KJ, Kobeissy F, Yao C, Lu XC, Dave JR, Shear DA, Schmid K, Rivera V, Cram T, Seaney J, Zhang Z, Wang KK, ... Hayes RL, et al. Biomarkers track damage after graded injury severity in a rat model of penetrating brain injury. Journal of Neurotrauma. 30: 1161-9. PMID 23409698 DOI: 10.1089/neu.2012.2762  0.6
2013 Massaro AN, Jeromin A, Kadom N, Vezina G, Hayes RL, Wang KK, Streeter J, Johnston MV. Serum biomarkers of MRI brain injury in neonatal hypoxic ischemic encephalopathy treated with whole-body hypothermia: a pilot study. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 14: 310-7. PMID 23392373 DOI: 10.1097/PCC.0b013e3182720642  0.6
2012 Mondello S, Palmio J, Streeter J, Hayes RL, Peltola J, Jeromin A. Ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) is increased in cerebrospinal fluid and plasma of patients after epileptic seizure. Bmc Neurology. 12: 85. PMID 22931063 DOI: 10.1186/1471-2377-12-85  0.6
2012 Mondello S, Gabrielli A, Catani S, D'Ippolito M, Jeromin A, Ciaramella A, Bossù P, Schmid K, Tortella F, Wang KK, Hayes RL, Formisano R. Increased levels of serum MAP-2 at 6-months correlate with improved outcome in survivors of severe traumatic brain injury. Brain Injury. 26: 1629-35. PMID 22794497 DOI: 10.3109/02699052.2012.700083  0.6
2012 Glushakova OY, Jeromin A, Martinez J, Johnson D, Denslow N, Streeter J, Hayes RL, Mondello S. Cerebrospinal fluid protein biomarker panel for assessment of neurotoxicity induced by kainic acid in rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 130: 158-67. PMID 22790971 DOI: 10.1093/toxsci/kfs224  0.6
2012 Papa L, Lewis LM, Silvestri S, Falk JL, Giordano P, Brophy GM, Demery JA, Liu MC, Mo J, Akinyi L, Mondello S, Schmid K, Robertson CS, Tortella FC, Hayes RL, et al. Serum levels of ubiquitin C-terminal hydrolase distinguish mild traumatic brain injury from trauma controls and are elevated in mild and moderate traumatic brain injury patients with intracranial lesions and neurosurgical intervention. The Journal of Trauma and Acute Care Surgery. 72: 1335-44. PMID 22673263 DOI: 10.1097/TA.0b013e3182491e3d  0.6
2012 Czeiter E, Mondello S, Kovacs N, Sandor J, Gabrielli A, Schmid K, Tortella F, Wang KK, Hayes RL, Barzo P, Ezer E, Doczi T, Buki A. Brain injury biomarkers may improve the predictive power of the IMPACT outcome calculator. Journal of Neurotrauma. 29: 1770-8. PMID 22435839 DOI: 10.1089/neu.2011.2127  0.6
2012 Svetlov SI, Prima V, Glushakova O, Svetlov A, Kirk DR, Gutierrez H, Serebruany VL, Curley KC, Wang KK, Hayes RL. Neuro-glial and systemic mechanisms of pathological responses in rat models of primary blast overpressure compared to "composite" blast. Frontiers in Neurology. 3: 15. PMID 22403567 DOI: 10.3389/fneur.2012.00015  0.6
2012 Mondello S, Jeromin A, Buki A, Bullock R, Czeiter E, Kovacs N, Barzo P, Schmid K, Tortella F, Wang KK, Hayes RL. Glial neuronal ratio: a novel index for differentiating injury type in patients with severe traumatic brain injury. Journal of Neurotrauma. 29: 1096-104. PMID 22165978 DOI: 10.1089/neu.2011.2092  0.6
2012 Papa L, Lewis LM, Falk JL, Zhang Z, Silvestri S, Giordano P, Brophy GM, Demery JA, Dixit NK, Ferguson I, Liu MC, Mo J, Akinyi L, Schmid K, Mondello S, ... ... Hayes RL, et al. Elevated levels of serum glial fibrillary acidic protein breakdown products in mild and moderate traumatic brain injury are associated with intracranial lesions and neurosurgical intervention. Annals of Emergency Medicine. 59: 471-83. PMID 22071014 DOI: 10.1016/j.annemergmed.2011.08.021  0.6
2012 Berger RP, Hayes RL, Richichi R, Beers SR, Wang KK. Serum concentrations of ubiquitin C-terminal hydrolase-L1 and αII-spectrin breakdown product 145 kDa correlate with outcome after pediatric TBI. Journal of Neurotrauma. 29: 162-7. PMID 22022780 DOI: 10.1089/neu.2011.1989  0.6
2012 Mondello S, Linnet A, Buki A, Robicsek S, Gabrielli A, Tepas J, Papa L, Brophy GM, Tortella F, Hayes RL, Wang KK. Clinical utility of serum levels of ubiquitin C-terminal hydrolase as a biomarker for severe traumatic brain injury. Neurosurgery. 70: 666-75. PMID 21937927 DOI: 10.1227/NEU.0b013e318236a809  0.6
2011 Zhang Z, Mondello S, Kobeissy F, Rubenstein R, Streeter J, Hayes RL, Wang KK. Protein biomarkers for traumatic and ischemic brain injury: from bench to bedside. Translational Stroke Research. 2: 455-62. PMID 24323681 DOI: 10.1007/s12975-011-0137-6  0.6
2011 Ehrenreich H, Kästner A, Weissenborn K, Streeter J, Sperling S, Wang KK, Worthmann H, Hayes RL, von Ahsen N, Kastrup A, Jeromin A, Herrmann M. Circulating damage marker profiles support a neuroprotective effect of erythropoietin in ischemic stroke patients. Molecular Medicine (Cambridge, Mass.). 17: 1306-10. PMID 21912808 DOI: 10.2119/molmed.2011.00259  0.6
2011 Hayes RL, Mondello S, Wang K. Glial fibrillary acidic protein: a promising biomarker in pediatric brain injury. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 12: 603-4. PMID 21897166 DOI: 10.1097/PCC.0b013e3182070f89  0.6
2011 Kochanek PM, Bramlett H, Dietrich WD, Dixon CE, Hayes RL, Povlishock J, Tortella FC, Wang KK. A novel multicenter preclinical drug screening and biomarker consortium for experimental traumatic brain injury: operation brain trauma therapy. The Journal of Trauma. 71: S15-24. PMID 21795873 DOI: 10.1097/TA.0b013e31822117fe  0.6
2011 Berger RP, Houle JF, Hayes RL, Wang KK, Mondello S, Bell MJ. Translating biomarkers research to clinical care: applications and issues for rehabilomics. Pm & R : the Journal of Injury, Function, and Rehabilitation. 3: S31-8. PMID 21703578 DOI: 10.1016/j.pmrj.2011.03.016  0.6
2011 Kobeissy FH, Guingab-Cagmat JD, Razafsha M, O'Steen L, Zhang Z, Hayes RL, Chiu WT, Wang KK. Leveraging biomarker platforms and systems biology for rehabilomics and biologics effectiveness research. Pm & R : the Journal of Injury, Function, and Rehabilitation. 3: S139-47. PMID 21703572 DOI: 10.1016/j.pmrj.2011.02.012  0.6
2011 Mondello S, Papa L, Buki A, Bullock MR, Czeiter E, Tortella FC, Wang KK, Hayes RL. Neuronal and glial markers are differently associated with computed tomography findings and outcome in patients with severe traumatic brain injury: a case control study. Critical Care (London, England). 15: R156. PMID 21702960 DOI: 10.1186/cc10286  0.6
2011 Liu MC, Kobeissy F, Zheng W, Zhang Z, Hayes RL, Wang KK. Dual vulnerability of tau to calpains and caspase-3 proteolysis under neurotoxic and neurodegenerative conditions. Asn Neuro. 3: e00051. PMID 21359008 DOI: 10.1042/AN20100012  0.6
2011 Brophy GM, Mondello S, Papa L, Robicsek SA, Gabrielli A, Tepas J, Buki A, Robertson C, Tortella FC, Hayes RL, Wang KK. Biokinetic analysis of ubiquitin C-terminal hydrolase-L1 (UCH-L1) in severe traumatic brain injury patient biofluids. Journal of Neurotrauma. 28: 861-70. PMID 21309726 DOI: 10.1089/neu.2010.1564  0.6
2011 Mondello S, Muller U, Jeromin A, Streeter J, Hayes RL, Wang KK. Blood-based diagnostics of traumatic brain injuries. Expert Review of Molecular Diagnostics. 11: 65-78. PMID 21171922 DOI: 10.1586/erm.10.104  0.6
2010 Manley GT, Diaz-Arrastia R, Brophy M, Engel D, Goodman C, Gwinn K, Veenstra TD, Ling G, Ottens AK, Tortella F, Hayes RL. Common data elements for traumatic brain injury: recommendations from the biospecimens and biomarkers working group. Archives of Physical Medicine and Rehabilitation. 91: 1667-72. PMID 21044710 DOI: 10.1016/j.apmr.2010.05.018  0.6
2010 Zhang Z, Larner SF, Kobeissy F, Hayes RL, Wang KK. Systems biology and theranostic approach to drug discovery and development to treat traumatic brain injury. Methods in Molecular Biology (Clifton, N.J.). 662: 317-29. PMID 20824479 DOI: 10.1007/978-1-60761-800-3_16  0.6
2010 Ottens AK, Bustamante L, Golden EC, Yao C, Hayes RL, Wang KKW, Tortella FC, Dave JR. Neuroproteomics: A biochemical means to discriminate the extent and modality of brain injury Journal of Neurotrauma. 27: 1837-1852. PMID 20698760 DOI: 10.1089/neu.2010.1374  0.6
2010 Martinez JA, Zhang Z, Svetlov SI, Hayes RL, Wang KK, Larner SF. Calpain and caspase processing of caspase-12 contribute to the ER stress-induced cell death pathway in differentiated PC12 cells. Apoptosis : An International Journal On Programmed Cell Death. 15: 1480-93. PMID 20640600 DOI: 10.1007/s10495-010-0526-4  0.6
2010 Mondello S, Robicsek SA, Gabrielli A, Brophy GM, Papa L, Tepas J, Robertson C, Buki A, Scharf D, Jixiang M, Akinyi L, Muller U, Wang KK, Hayes RL. αII-spectrin breakdown products (SBDPs): diagnosis and outcome in severe traumatic brain injury patients. Journal of Neurotrauma. 27: 1203-13. PMID 20408766 DOI: 10.1089/neu.2010.1278  0.6
2010 Liu MC, Akinyi L, Scharf D, Mo J, Larner SF, Muller U, Oli MW, Zheng W, Kobeissy F, Papa L, Lu XC, Dave JR, Tortella FC, Hayes RL, Wang KK. Ubiquitin C-terminal hydrolase-L1 as a biomarker for ischemic and traumatic brain injury in rats. The European Journal of Neuroscience. 31: 722-32. PMID 20384815 DOI: 10.1111/j.1460-9568.2010.07097.x  0.6
2010 Svetlov SI, Prima V, Kirk DR, Gutierrez H, Curley KC, Hayes RL, Wang KK. Morphologic and biochemical characterization of brain injury in a model of controlled blast overpressure exposure. The Journal of Trauma. 69: 795-804. PMID 20215974 DOI: 10.1097/TA.0b013e3181bbd885  0.6
2010 Sadasivan S, Zhang Z, Larner SF, Liu MC, Zheng W, Kobeissy FH, Hayes RL, Wang KK. Acute NMDA toxicity in cultured rat cerebellar granule neurons is accompanied by autophagy induction and late onset autophagic cell death phenotype. Bmc Neuroscience. 11: 21. PMID 20167092 DOI: 10.1186/1471-2202-11-21  0.6
2010 Papa L, Akinyi L, Liu MC, Pineda JA, Tepas JJ, Oli MW, Zheng W, Robinson G, Robicsek SA, Gabrielli A, Heaton SC, Hannay HJ, Demery JA, Brophy GM, Layon J, ... ... Hayes RL, et al. Ubiquitin C-terminal hydrolase is a novel biomarker in humans for severe traumatic brain injury. Critical Care Medicine. 38: 138-44. PMID 19726976 DOI: 10.1097/CCM.0b013e3181b788ab  0.6
2009 Hayes RL, Robinson G, Muller U, Wang KK. Translation of neurological biomarkers to clinically relevant platforms. Methods in Molecular Biology (Clifton, N.J.). 566: 303-13. PMID 20058180 DOI: 10.1007/978-1-59745-562-6_20  0.6
2009 Oli MW, Hayes RL, Robinson G, Wang KK. Traumatic brain injury biomarkers: from pipeline to diagnostic assay development. Methods in Molecular Biology (Clifton, N.J.). 566: 293-302. PMID 20058179 DOI: 10.1007/978-1-59745-562-6_19  0.6
2009 Zhang Z, Larner SF, Liu MC, Zheng W, Hayes RL, Wang KK. Multiple alphaII-spectrin breakdown products distinguish calpain and caspase dominated necrotic and apoptotic cell death pathways. Apoptosis : An International Journal On Programmed Cell Death. 14: 1289-98. PMID 19771521 DOI: 10.1007/s10495-009-0405-z  0.6
2009 Weiss ES, Wang KK, Allen JG, Blue ME, Nwakanma LU, Liu MC, Lange MS, Berrong J, Wilson MA, Gott VL, Troncoso JC, Hayes RL, Johnston MV, Baumgartner WA. Alpha II-spectrin breakdown products serve as novel markers of brain injury severity in a canine model of hypothermic circulatory arrest. The Annals of Thoracic Surgery. 88: 543-50. PMID 19632410 DOI: 10.1016/j.athoracsur.2009.04.016  0.6
2009 Mazzeo AT, Brophy GM, Gilman CB, Alves OL, Robles JR, Hayes RL, Povlishock JT, Bullock MR. Safety and tolerability of cyclosporin a in severe traumatic brain injury patients: results from a prospective randomized trial. Journal of Neurotrauma. 26: 2195-206. PMID 19621985 DOI: 10.1089/neu.2009.1012  0.6
2009 Svetlov SI, Larner SF, Kirk DR, Atkinson J, Hayes RL, Wang KK. Biomarkers of blast-induced neurotrauma: profiling molecular and cellular mechanisms of blast brain injury. Journal of Neurotrauma. 26: 913-21. PMID 19422293 DOI: 10.1089/neu.2008.0609  0.6
2009 Yao C, Williams AJ, Ottens AK, Lu XCM, Liu MCh, Hayes RL, Wang KK, Tortella FC, Dave JR. P43/pro-EMAPII: a potential biomarker for discriminating traumatic versus ischemic brain injury Journal of Neurotrauma. 26: 1295-1305. PMID 19317603 DOI: 10.1089/neu.2008-0811  0.6
2009 McGinn MJ, Kelley BJ, Akinyi L, Oli MW, Liu MC, Hayes RL, Wang KK, Povlishock JT. Biochemical, structural, and biomarker evidence for calpain-mediated cytoskeletal change after diffuse brain injury uncomplicated by contusion. Journal of Neuropathology and Experimental Neurology. 68: 241-9. PMID 19225412 DOI: 10.1097/NEN.0b013e3181996bfe  0.6
2009 Brophy GM, Pineda JA, Papa L, Lewis SB, Valadka AB, Hannay HJ, Heaton SC, Demery JA, Liu MC, Tepas JJ, Gabrielli A, Robicsek S, Wang KK, Robertson CS, Hayes RL. alphaII-Spectrin breakdown product cerebrospinal fluid exposure metrics suggest differences in cellular injury mechanisms after severe traumatic brain injury. Journal of Neurotrauma. 26: 471-9. PMID 19206997 DOI: 10.1089/neu.2008.0657  0.6
2008 Papa L, Robinson G, Oli M, Pineda J, Demery J, Brophy G, Robicsek SA, Gabrielli A, Robertson CS, Wang KK, Hayes RL. Use of biomarkers for diagnosis and management of traumatic brain injury patients. Expert Opinion On Medical Diagnostics. 2: 937-45. PMID 23495867 DOI: 10.1517/17530059.2.8.937  0.6
2008 Kobeissy FH, Sadasivan S, Oli MW, Robinson G, Larner SF, Zhang Z, Hayes RL, Wang KK. Neuroproteomics and systems biology-based discovery of protein biomarkers for traumatic brain injury and clinical validation. Proteomics. Clinical Applications. 2: 1467-83. PMID 21136795 DOI: 10.1002/prca.200800011  0.6
2008 Cox CD, West EJ, Liu MC, Wang KK, Hayes RL, Lyeth BG. Dicyclomine, an M1 muscarinic antagonist, reduces biomarker levels, but not neuronal degeneration, in fluid percussion brain injury. Journal of Neurotrauma. 25: 1355-65. PMID 19061379 DOI: 10.1089/neu.2008.0671  0.6
2008 Mazzeo AT, Alves OL, Gilman CB, Hayes RL, Tolias C, Niki Kunene K, Ross Bullock M. Brain metabolic and hemodynamic effects of cyclosporin A after human severe traumatic brain injury: a microdialysis study. Acta Neurochirurgica. 150: 1019-31; discussion . PMID 18781275 DOI: 10.1007/s00701-008-0021-7  0.6
2008 Yao C, Williams AJ, Ottens AK, Lu XCM, Chen R, Wang KK, Hayes RL, Tortella FC, Dave JR. Detection of protein biomarkers using high-throughput immunoblotting following focal ischemic or penetrating ballistic-like brain injuries in rats Brain Injury. 22: 723-732. PMID 18720098 DOI: 10.1080/02699050802304706  0.6
2008 Sadasivan S, Dunn WA, Hayes RL, Wang KK. Changes in autophagy proteins in a rat model of controlled cortical impact induced brain injury. Biochemical and Biophysical Research Communications. 373: 478-81. PMID 18486600 DOI: 10.1016/j.bbrc.2008.05.031  0.6
2008 Ottens AK, Golden EC, Bustamante L, Hayes RL, Denslow ND, Wang KKW. Proteolysis of multiple myelin basic protein isoforms after neurotrauma: Characterization by mass spectrometry Journal of Neurochemistry. 104: 1404-1414. PMID 18036155 DOI: 10.1111/j.1471-4159.2007.05086.x  0.6
2007 Lewis SB, Velat GJ, Miralia L, Papa L, Aikman JM, Wolper RA, Firment CS, Liu MC, Pineda JA, Wang KK, Hayes RL. Alpha-II spectrin breakdown products in aneurysmal subarachnoid hemorrhage: a novel biomarker of proteolytic injury. Journal of Neurosurgery. 107: 792-6. PMID 17937225 DOI: 10.3171/JNS-07/10/0792  0.6
2007 Warren MW, Larner SF, Kobeissy FH, Brezing CA, Jeung JA, Hayes RL, Gold MS, Wang KK. Calpain and caspase proteolytic markers co-localize with rat cortical neurons after exposure to methamphetamine and MDMA. Acta Neuropathologica. 114: 277-86. PMID 17647000 DOI: 10.1007/s00401-007-0259-9  0.6
2007 Ottens AK, Kobeissy FH, Fuller BF, Chen Liu M, Oli MW, Hayes RL, Wang KKW. Novel neuroproteomic approaches to studying traumatic brain injury Progress in Brain Research. 161: 401-418. PMID 17618994 DOI: 10.1016/S0079-6123(06)61029-7  0.6
2007 Germanò A, Caffo M, Angileri FF, Arcadi F, Newcomb-Fernandez J, Caruso G, Meli F, Pineda JA, Lewis SB, Wang KK, Bramanti P, Costa C, Hayes RL. NMDA receptor antagonist felbamate reduces behavioral deficits and blood-brain barrier permeability changes after experimental subarachnoid hemorrhage in the rat. Journal of Neurotrauma. 24: 732-44. PMID 17439355 DOI: 10.1089/neu.2006.0181  0.6
2007 Zhang Z, Ottens AK, Sadasivan S, Kobeissy FH, Fang T, Hayes RL, Wang KKW. Calpain-mediated collapsin response mediator protein-1, -2, and -4 proteolysis after neurotoxic and traumatic brain injury Journal of Neurotrauma. 24: 460-472. PMID 17402852 DOI: 10.1089/neu.2006.0078  0.6
2007 Pineda JA, Lewis SB, Valadka AB, Papa L, Hannay HJ, Heaton SC, Demery JA, Liu MC, Aikman JM, Akle V, Brophy GM, Tepas JJ, Wang KK, Robertson CS, Hayes RL. Clinical significance of alphaII-spectrin breakdown products in cerebrospinal fluid after severe traumatic brain injury. Journal of Neurotrauma. 24: 354-66. PMID 17375999 DOI: 10.1089/neu.2006.003789  0.6
2007 Warren MW, Zheng W, Kobeissy FH, Cheng Liu M, Hayes RL, Gold MS, Larner SF, Wang KK. Calpain- and caspase-mediated alphaII-spectrin and tau proteolysis in rat cerebrocortical neuronal cultures after ecstasy or methamphetamine exposure. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 10: 479-89. PMID 16882358 DOI: 10.1017/S1461145706007061  0.6
2006 Wang KK, Larner SF, Robinson G, Hayes RL. Neuroprotection targets after traumatic brain injury. Current Opinion in Neurology. 19: 514-9. PMID 17102687 DOI: 10.1097/WCO.0b013e3280102b10  0.6
2006 Warren MW, Kobeissy FH, Liu MC, Hayes RL, Gold MS, Wang KK. Ecstasy toxicity: a comparison to methamphetamine and traumatic brain injury. Journal of Addictive Diseases. 25: 115-23. PMID 17088231 DOI: 10.1300/J069v25n04_11  0.6
2006 Xiang Y, Johnson EA, Zhang C, Huang G, Hayes RL, Wang KK, Svetlov SI. Generation of aberrant forms of DFF40 concurrent with caspase-3 activation during acute and chronic liver injury in rats. Biochemical and Biophysical Research Communications. 350: 457-62. PMID 17011520 DOI: 10.1016/j.bbrc.2006.09.068  0.6
2006 Liu MC, Akle V, Zheng W, Kitlen J, O'Steen B, Larner SF, Dave JR, Tortella FC, Hayes RL, Wang KK. Extensive degradation of myelin basic protein isoforms by calpain following traumatic brain injury. Journal of Neurochemistry. 98: 700-12. PMID 16893416 DOI: 10.1111/j.1471-4159.2006.03882.x  0.6
2006 Zhang Z, Ottens AK, Larner SF, Kobeissy FH, Williams ML, Hayes RL, Wang KK. Direct Rho-associated kinase inhibition [correction of inhibiton] induces cofilin dephosphorylation and neurite outgrowth in PC-12 cells. Cellular & Molecular Biology Letters. 11: 12-29. PMID 16847745 DOI: 10.2478/s11658-006-0002-x  0.6
2006 Kobeissy FH, Ottens AK, Zhang Z, Liu MC, Denslow ND, Dave JR, Tortella FC, Hayes RL, Wang KKW. Novel differential neuroproteomics analysis of traumatic brain injury in rats Molecular and Cellular Proteomics. 5: 1887-1898. PMID 16801361 DOI: 10.1074/mcp.M600157-MCP200  0.6
2006 Larner SF, Hayes RL, Wang KK. Unfolded protein response after neurotrauma. Journal of Neurotrauma. 23: 807-29. PMID 16774469 DOI: 10.1089/neu.2006.23.807  0.6
2006 Sadasivan S, Waghray A, Larner SF, Dunn WA, Hayes RL, Wang KK. Amino acid starvation induced autophagic cell death in PC-12 cells: evidence for activation of caspase-3 but not calpain-1. Apoptosis : An International Journal On Programmed Cell Death. 11: 1573-82. PMID 16703260 DOI: 10.1007/s10495-006-7690-6  0.6
2006 Ottens AK, Kobeissy FH, Golden EC, Zhang Z, Haskins WE, Chen SS, Hayes RL, Wang KKW, Denslow ND. Neuroproteomics in neurotrauma Mass Spectrometry Reviews. 25: 380-408. PMID 16498609 DOI: 10.1002/mas.20073  0.6
2006 Liu MC, Akle V, Zheng W, Dave JR, Tortella FC, Hayes RL, Wang KKW. Comparing calpain- and caspase-3-mediated degradation patterns in traumatic brain injury by differential proteome analysis Biochemical Journal. 394: 715-725. PMID 16351572 DOI: 10.1042/BJ20050905  0.6
2006 Bernath E, Kupina N, Liu MC, Hayes RL, Meegan C, Wang KKW. Elevation of cytoskeletal protein breakdown in aged Wistar rat brain Neurobiology of Aging. 27: 624-632. PMID 15913844 DOI: 10.1016/j.neurobiolaging.2005.02.013  0.6
2005 Johnson EA, Svetlov SI, Wang KK, Hayes RL, Pineda JA. Cell-specific DNA fragmentation may be attenuated by a survivin-dependent mechanism after traumatic brain injury in rats. Experimental Brain Research. 167: 17-26. PMID 16193270 DOI: 10.1007/s00221-005-2362-2  0.6
2005 Warren MW, Kobeissy FH, Liu MC, Hayes RL, Gold MS, Wang KKW. Concurrent calpain and caspase-3 mediated proteolysis of αII-spectrin and tau in rat brain after methamphetamine exposure: A similar profile to traumatic brain injury Life Sciences. 78: 301-309. PMID 16125733 DOI: 10.1016/j.lfs.2005.04.058  0.6
2005 Wang KKW, Ottens AK, Liu MC, Lewis SB, Meegan C, Oli MW, Tortella FC, Hayes RL. Proteomic identification of biomarkers of traumatic brain injury Expert Review of Proteomics. 2: 603-614. PMID 16097892 DOI: 10.1586/14789450.2.4.603  0.6
2005 Ottens AK, Kobeissy FH, Wolper RA, Haskins WE, Hayes RL, Denslow ND, Wang KKW. A multidimensional differential proteomic platform using dual-phase ion-exchange chromatography-polyacrylamide gel electrophoresis/reversed-phase liquid chromatography tandem mass spectrometry Analytical Chemistry. 77: 4836-4845. PMID 16053296 DOI: 10.1021/ac050478r  0.6
2005 Larner SF, McKinsey DM, Hayes RL, Wang KKW. Caspase 7: Increased expression and activation after traumatic brain injury in rats Journal of Neurochemistry. 94: 97-108. PMID 15953353 DOI: 10.1111/j.1471-4159.2005.03172.x  0.6
2005 Haskins WE, Kobeissy FH, Wolper RA, Ottens AK, Kitlen JW, McClung SH, O'Steen BE, Chow MM, Pineda JA, Denslow ND, Hayes RL, Wang KK. Rapid discovery of putative protein biomarkers of traumatic brain injury by SDS-PAGE-capillary liquid chromatography-tandem mass spectrometry. Journal of Neurotrauma. 22: 629-44. PMID 15941373 DOI: 10.1089/neu.2005.22.629  0.6
2005 Ellis RC, O'Steen WA, Hayes RL, Nick HS, Wang KK, Anderson DK. Cellular localization and enzymatic activity of cathepsin B after spinal cord injury in the rat. Experimental Neurology. 193: 19-28. PMID 15817261 DOI: 10.1016/j.expneurol.2004.11.034  0.6
2004 Svetlov SI, Ignatova TN, Wang KK, Hayes RL, English D, Kukekov VG. Lysophosphatidic acid induces clonal generation of mouse neurospheres via proliferation of Sca-1- and AC133-positive neural progenitors. Stem Cells and Development. 13: 685-93. PMID 15684836 DOI: 10.1089/scd.2004.13.685  0.6
2004 Wang KKW, Ottens A, Haskins W, Cheng Liu M, Kobeissy F, Denslow N, Chen S, Hayes RL. Proteomics Studies of Traumatic Brain Injury International Review of Neurobiology. 61: 215-240. PMID 15482817 DOI: 10.1016/S0074-7742(04)61009-9  0.6
2004 Waghray A, Wang DS, McKinsey D, Hayes RL, Wang KKW. Molecular cloning and characterization of rat and human calpain-5 Biochemical and Biophysical Research Communications. 324: 46-51. PMID 15464980 DOI: 10.1016/j.bbrc.2004.09.012  0.6
2004 Johnson EA, Svetlov SI, Pike BR, Tolentino PJ, Shaw G, Wang KK, Hayes RL, Pineda JA. Cell-specific upregulation of survivin after experimental traumatic brain injury in rats. Journal of Neurotrauma. 21: 1183-95. PMID 15453988 DOI: 10.1089/neu.2004.21.1183  0.6
2004 Pineda JA, Wang KK, Hayes RL. Biomarkers of proteolytic damage following traumatic brain injury. Brain Pathology (Zurich, Switzerland). 14: 202-9. PMID 15193033  0.6
2004 Tolentino PJ, Waghray A, Wang KKW, Hayes RL. Increased expression of tissue-type transglutaminase following middle cerebral artery occlusion in rats Journal of Neurochemistry. 89: 1301-1307. PMID 15147523 DOI: 10.1111/j.1471-4159.2004.02436.x  0.6
2004 Ellis RC, Earnhardt JN, Hayes RL, Wang KK, Anderson DK. Cathepsin B mRNA and protein expression following contusion spinal cord injury in rats. Journal of Neurochemistry. 88: 689-97. PMID 14720218 DOI: 10.1046/j.1471-4159.2003.02197.x  0.6
2004 Pike BR, Flint J, Dave JR, Lu XC, Wang KK, Tortella FC, Hayes RL. Accumulation of calpain and caspase-3 proteolytic fragments of brain-derived alphaII-spectrin in cerebral spinal fluid after middle cerebral artery occlusion in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 98-106. PMID 14688621 DOI: 10.1097/01.WCB.0000098520.11962.37  0.6
2004 Larner SF, Hayes RL, McKinsey DM, Pike BR, Wang KKW. Increased expression and processing of caspase-12 after traumatic brain injury in rats Journal of Neurochemistry. 88: 78-90. PMID 14675152  0.6
2003 Shepherd TM, Thelwall PE, Blackband SJ, Pike BR, Hayes RL, Wirth ED. Diffusion magnetic resonance imaging study of a rat hippocampal slice model for acute brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 1461-70. PMID 14663342 DOI: 10.1097/01.WCB.0000100852.67976.C2  0.6
2003 Denslow N, Michel ME, Temple MD, Hsu CY, Saatman K, Hayes RL. Application of proteomics technology to the field of neurotrauma Journal of Neurotrauma. 20: 401-407. PMID 12803973  0.6
2002 Franz G, Beer R, Intemann D, Krajewski S, Reed JC, Engelhardt K, Pike BR, Hayes RL, Wang KK, Schmutzhard E, Kampfl A. Temporal and spatial profile of Bid cleavage after experimental traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 951-8. PMID 12172380 DOI: 10.1097/00004647-200208000-00006  0.6
2002 Tolentino PJ, DeFord SM, Notterpek L, Glenn CC, Pike BR, Wang KK, Hayes RL. Up-regulation of tissue-type transglutaminase after traumatic brain injury. Journal of Neurochemistry. 80: 579-88. PMID 11841565 DOI: 10.1046/j.0022-3042.2001.00726.x  0.6
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