Patrick M. Kochanek - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 

500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kochanek PM, Jha RM. Fluid therapy after brain injury: the pendulum swings again. The Lancet. Neurology. 20: 587-589. PMID 34302775 DOI: 10.1016/S1474-4422(21)00204-0  1
2021 Kernan KF, Berger RP, Clark RSB, Scott Watson R, Angus DC, Panigrahy A, Callaway CW, Bell MJ, Kochanek PM, Fink EL, Simon DW. An Exploratory Assessment of Serum Biomarkers of Post-Cardiac Arrest Syndrome in Children. Resuscitation. PMID 34271122 DOI: 10.1016/j.resuscitation.2021.07.007  1
2021 Zusman BE, Dixon CE, Jha RM, Vagni V, Henchir J, Carlson SW, Janesko-Feldman K, Bailey Z, Shear DA, Gilsdorf J, Kochanek PM. Choice of Whole Blood versus Lactated Ringers Resuscitation Modifies the Relationship Between Blood Pressure Target and Functional Outcome after Traumatic Brain Injury Plus Hemorrhagic Shock in Mice. Journal of Neurotrauma. PMID 34269621 DOI: 10.1089/neu.2021.0157  1
2021 Smith DH, Kochanek PM, Rosi S, Meyer R, Ferland-Beckham C, Prager EM, Ahlers S, Crawford FC. Roadmap for Advancing Preclinical Science in Traumatic Brain Injury. Journal of Neurotrauma. PMID 34210174 DOI: 10.1089/neu.2021.0094  0.01
2021 Simon DW, McGeachy MJ, Kochanek PM. Targeting "Natural Born Killers" to Modulate Immune Suppression in Neurocritical Care. Neurocritical Care. PMID 34061313 DOI: 10.1007/s12028-021-01235-y  1
2021 Raghu VK, Horvat CM, Kochanek PM, Fink EL, Clark RSB, Benos PV, Au AK. Neurological Complications Acquired During Pediatric Critical Illness: Exploratory "Mixed Graphical Modeling" Analysis Using Serum Biomarker Levels. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 34054117 DOI: 10.1097/PCC.0000000000002776  1
2021 Soysal E, Horvat CM, Simon DW, Wolf MS, Tyler-Kabara E, Gaines BA, Clark RSB, Kochanek PM, Bayir H. Clinical Deterioration and Neurocritical Care Utilization in Pediatric Patients With Glasgow Coma Scale Score of 9-13 After Traumatic Brain Injury: Associations With Patient and Injury Characteristics. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 34038066 DOI: 10.1097/PCC.0000000000002767  1
2021 Opeyemi OM, Rogers MB, Firek B, Janesko-Feldman K, Vagni V, Mullett SJ, Wendell S, Nelson BP, New LA, Mariño E, Kochanek PM, Bayir H, Clark RSB, Morowitz MJ, Simon DW. Sustained Dysbiosis and Decreased Fecal Short Chain Fatty Acids after Traumatic Brain Injury and Impact on Neurologic Outcome. Journal of Neurotrauma. PMID 33957773 DOI: 10.1089/neu.2020.7506  1
2021 Yu F, Saand A, Xing C, Lee JW, Hsu L, Palmer OP, Jackson V, Tang L, Ning M, Du R, Kochanek PM, Lo EH, Chou SH. CSF lipocalin-2 increases early in subarachnoid hemorrhage are associated with neuroinflammation and unfavorable outcome. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211012110. PMID 33951946 DOI: 10.1177/0271678X211012110  0.01
2021 Tata S, Zusman BE, Kochanek PM, Gerzanich V, Kwon MS, Woo SK, Clark RS, Janesko-Feldman K, Vagni V, Simard JM, Jha RM. Abcc8 (Sulfonylurea Receptor-1) Impact on Brain Atrophy after TBI Varies by Sex. Journal of Neurotrauma. PMID 33940936 DOI: 10.1089/neu.2021.0105  1
2021 Wolf MS, Manole MD, New LA, Chen Y, Soysal E, Kochanek PM, Bayır H, Clark RSB. Ascorbate deficiency confers resistance to hippocampal neurodegeneration after asphyxial cardiac arrest in juvenile rats. Pediatric Research. PMID 33846553 DOI: 10.1038/s41390-021-01515-5  1
2021 Osier N, Bramlett HM, Shear DA, Mondello S, Carlson SW, Dietrich WD, Deng-Bryant Y, Wang KKW, Hayes RL, Yang Z, Empey PE, Poloyac SM, Lafrenaye AD, Povlishock J, Gilsdorf J, ... Kochanek PM, et al. Kollidon VA64 Treatment in Traumatic Brain Injury, Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 33843262 DOI: 10.1089/neu.2021.0089  1
2021 Madurski C, Jarvis JM, Beers SR, Houtrow AJ, Wagner AK, Fabio A, Wang C, Smith CM, Doughty L, Janesko-Feldman K, Rubin P, Pollon D, Treble-Barna A, Kochanek PM, Fink EL, et al. Serum Biomarkers of Regeneration and Plasticity are Associated with Functional Outcome in Pediatric Neurocritical Illness: An Exploratory Study. Neurocritical Care. PMID 33665769 DOI: 10.1007/s12028-021-01199-z  1
2021 Uray T, Dezfulian C, Palmer AA, Miner KM, Leak RK, Stezoski JP, Janesko-Feldman K, Kochanek PM, Drabek T. Cardiac Arrest Induced by Asphyxia Versus Ventricular Fibrillation Elicits Comparable Early Changes in Cytokine Levels in the Rat Brain, Heart, and Serum. Journal of the American Heart Association. 10: e018657. PMID 33599149 DOI: 10.1161/JAHA.120.018657  1
2021 Zusman BE, Kochanek PM, Bell MJ, Adelson PD, Wisniewski SR, Au A, Clark RS, Bayir H, Janesko-Feldman K, Jha RM. Cerebrospinal fluid Sulfonylurea Receptor-1 is associated with intracranial pressure and outcome after pediatric TBI-an exploratory analysis of the Cool Kids Trial. Journal of Neurotrauma. PMID 33430695 DOI: 10.1089/neu.2020.7501  1
2021 Jackson TC, Gorse K, Herrmann JR, Kochanek PM. Hippocampal and Prefrontal Cortical Brain Tissue Levels of Irisin and GDF15 Receptor Subunits in Children. Molecular Neurobiology. PMID 33411243 DOI: 10.1007/s12035-020-02250-4  1
2020 Zusman BE, Kochanek PM, Jha RM. Cerebral Edema in Traumatic Brain Injury: a Historical Framework for Current Therapy. Current Treatment Options in Neurology. 22. PMID 34177248 DOI: 10.1007/s11940-020-0614-x  1
2020 Kochanek PM. Smiling on the Bright Future of Pediatric Critical Care Medicine and the "Task(er)" at Hand. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 21: 1033-1034. PMID 33951719 DOI: 10.1097/PCC.0000000000002613  0.01
2020 Lafrenaye A, Mondello S, Povlishock J, Gorse K, Walker S, Hayes R, Wang K, Kochanek PM. Operation Brain Trauma Therapy: An Exploratory Study of Levetiracetam Treatment Following Mild Traumatic Brain Injury in the Micro Pig. Frontiers in Neurology. 11: 586958. PMID 33584493 DOI: 10.3389/fneur.2020.586958  1
2020 Nacoti M, Fazzi F, Biroli F, Zangari R, Barbui T, Kochanek PM. Addressing Key Clinical Care and Clinical Research Needs in Severe Pediatric Traumatic Brain Injury: Perspectives From a Focused International Conference. Frontiers in Pediatrics. 8: 594425. PMID 33537259 DOI: 10.3389/fped.2020.594425  0.01
2020 Kochanek PM. Smiling on the Bright Future of Pediatric Critical Care Medicine and the "Task(er)" at Hand. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 21: 1033-1034. PMID 33278211 DOI: 10.1097/PCC.0000000000002613  0.01
2020 Kochanek PM, Manole MD, Callaway CW. Strengthening the link between pre-clinical and clinical resuscitation research. Resuscitation. PMID 33249254 DOI: 10.1016/j.resuscitation.2020.11.008  1
2020 Woods KS, Horvat CM, Kantawala S, Simon DW, Rakkar J, Kochanek PM, Clark RSB, Au AK. Intracranial and Cerebral Perfusion Pressure Thresholds Associated With Inhospital Mortality Across Pediatric Neurocritical Care. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 33229873 DOI: 10.1097/PCC.0000000000002618  1
2020 Jha R, Mondello S, Bramlett HM, Dixon CE, Shear DA, Dietrich WD, Wang KKW, Yang Z, Hayes RL, Poloyac SM, Empey PE, Lafrenaye AD, Yan HQ, Carlson SW, Povlishock J, ... ... Kochanek PM, et al. Glibenclamide Treatment in Traumatic Brain Injury-Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 33203303 DOI: 10.1089/neu.2020.7421  1
2020 DeKosky ST, Kochanek PM, Valadka A, Clark RSB, Chou SHY, Au A, Horvat CM, Jha RM, Mannix R, Wisniewski SR, Wintermark M, Rowell SE, Welch RD, Lewis LM, House S, et al. Blood Biomarkers for Detection of Brain Injury in COVID-19 Patients. Journal of Neurotrauma. PMID 33115334 DOI: 10.1089/neu.2020.7332  1
2020 Bailey ZS, Leung LY, Yang X, Cardiff K, Gilsdorf J, Shear D, Kochanek PM. Pre-Hospital Whole Blood Resuscitation Reduces Fluid Requirement While Maintaining Critical Physiology in a Model of Penetrating Traumatic Brain Injury and Hemorrhage: Implications on Resource-Limited Combat Casualty Care. Shock (Augusta, Ga.). PMID 32925600 DOI: 10.1097/Shk.0000000000001662  1
2020 Zusman BE, Kochanek PM, Bailey ZS, Leung LY, Vagni VA, Okonkwo DO, Puccio AM, Shutter LA, Janesko-Feldman KL, Gilsdorf JS, Shear DA, Jha RM. Multifaceted Benefit of Whole Blood Versus Lactated Ringer's Resuscitation After Traumatic Brain Injury and Hemorrhagic Shock in Mice. Neurocritical Care. PMID 32886294 DOI: 10.1007/S12028-020-01084-1  1
2020 Simon DW, Rogers MB, Gao Y, Vincent G, Firek BA, Janesko-Feldman K, Vagni V, Kochanek PM, Ozolek JA, Mollen KP, Clark RSB, Morowitz MJ. Depletion of Gut Microbiota is Associated with Improved Neurologic Outcome Following Traumatic Brain Injury. Brain Research. 147056. PMID 32798452 DOI: 10.1016/J.Brainres.2020.147056  1
2020 Lafrenaye AD, Mondello S, Wang KK, Yang Z, Povlishock JT, Gorse K, Walker S, Hayes RL, Kochanek PM. Circulating GFAP and Iba-1 levels are associated with pathophysiological sequelae in the thalamus in a pig model of mild TBI. Scientific Reports. 10: 13369. PMID 32770054 DOI: 10.1038/S41598-020-70266-W  1
2020 Jackson TC, Kochanek PM. RNA Binding Motif 5 (RBM5) in the CNS-Moving Beyond Cancer to Harness RNA Splicing to Mitigate the Consequences of Brain Injury. Frontiers in Molecular Neuroscience. 13: 126. PMID 32765218 DOI: 10.3389/Fnmol.2020.00126  1
2020 Fink EL, Wisnowski J, Clark R, Berger RP, Fabio A, Furtado A, Narayan S, Angus DC, Watson RS, Wang C, Callaway CW, Bell MJ, Kochanek PM, Bluml S, Panigrahy A. Brain MR imaging and spectroscopy for outcome prognostication after pediatric cardiac arrest. Resuscitation. PMID 32653571 DOI: 10.1016/J.Resuscitation.2020.06.033  1
2020 Treble-Barna A, Patronick J, Uchani S, Marousis NC, Zigler CK, Fink EL, Kochanek PM, Conley YP, Yeates KO. Epigenetic Effects on Pediatric Traumatic Brain Injury Recovery (EETR): An Observational, Prospective, Longitudinal Concurrent Cohort Study Protocol. Frontiers in Neurology. 11: 460. PMID 32595586 DOI: 10.3389/Fneur.2020.00460  1
2020 Wolf MS, Rakkar J, Horvat CM, Simon DW, Kochanek PM, Clermont G, Clark RSB. Assessment of Dynamic Intracranial Compliance in Children with Severe Traumatic Brain Injury: Proof-of-Concept. Neurocritical Care. PMID 32556856 DOI: 10.1007/S12028-020-01004-3  1
2020 Even KM, Subramanian S, Berger RP, Kochanek PM, Zuccoli G, Gaines BA, Fink EL. The Presence of Anemia in Children with Abusive Head Trauma. The Journal of Pediatrics. PMID 32532650 DOI: 10.1016/J.Jpeds.2020.04.008  1
2020 Kochanek PM, Kudchadkar SR, Kissoon N. Pediatric Critical Care Medicine in the COVID-19 Pandemic. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 32516222 DOI: 10.1097/Pcc.0000000000002496  1
2020 Frontera J, Mainali S, Fink EL, Robertson CL, Schober M, Ziai W, Menon D, Kochanek PM, Suarez JI, Helbok R, McNett M, Chou SH. Global Consortium Study of Neurological Dysfunction in COVID-19 (GCS-NeuroCOVID): Study Design and Rationale. Neurocritical Care. PMID 32445105 DOI: 10.1007/S12028-020-00995-3  1
2020 Alcamo AM, Lavezoli R, Dezfulian C, Simon DW, Aneja RK, Clark RSB, Kochanek PM, Fink EL. Feasibility and Performance of a Gel-Adhesive Pad System for Pediatric Targeted Temperature Management: An Exploratory Analysis of 19 Pediatric Critically Ill Patients. Therapeutic Hypothermia and Temperature Management. PMID 32429750 DOI: 10.1089/Ther.2020.0011  1
2020 Jackson TC, Janesko-Feldman K, Gorse K, Vagni VA, Jackson EK, Kochanek PM. Identification of novel targets of RBM5 in the healthy and injured brain. Neuroscience. PMID 32335213 DOI: 10.1016/J.Neuroscience.2020.04.024  1
2020 Leisman DE, Harhay MO, Lederer DJ, Abramson M, Adjei AA, Bakker J, Ballas ZK, Barreiro E, Bell SC, Bellomo R, Bernstein JA, Branson RD, Brusasco V, Chalmers JD, Chokroverty S, ... ... Kochanek PM, et al. Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals. Critical Care Medicine. PMID 32141923 DOI: 10.1097/Ccm.0000000000004246  0.01
2020 Kochanek PM, Jha RM, Clark RSB. "Take a Number"-Precision Monitoring Directs Precision Therapy. Neurocritical Care. PMID 32141034 DOI: 10.1007/S12028-020-00941-3  1
2020 Kochanek PM. A Perfect Tribute to the Tremendous Academic Growth of Pediatric Critical Care Medicine in Turkey. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 21: 1. PMID 31899748 DOI: 10.1097/Pcc.0000000000002195  0.01
2020 Pang D, Wu Y, Alcamo A, Cummings J, Caro VD, Walko T, Hsue V, Clark R, Panigrahy A, Kochanek P, Aneja R. 1691: Axonal Injury, Cytotoxic Cerebral Edema, And Microglial Activation In A Mouse Model Of Sepsis Critical Care Medicine. 48: 820. DOI: 10.1097/01.Ccm.0000648664.77079.5B  1
2020 Rakkar J, Wolf M, Simon D, Kochanek P, Clermont G, Clark R, Horvat C. 691: Electronic Pediatric Intensity Level Of Therapy Score To Predict Mortality In Icp-Monitored Patients Critical Care Medicine. 48: 326. DOI: 10.1097/01.Ccm.0000626504.21575.09  1
2020 Wolf M, Rakkar J, Horvat C, Simon D, Kochanek P, Clermont G, Clark R. 690: Dynamic Assessment Of Intracranial Compliance In Pediatric Traumatic Brain Injury Critical Care Medicine. 48: 325. DOI: 10.1097/01.Ccm.0000626500.44446.6F  1
2020 Azar J, Kantawala S, Kochanek P, Clark R, Horvat C. 445: Increased Mortality Risk In Underweight Critically Ill Children Critical Care Medicine. 48: 203. DOI: 10.1097/01.Ccm.0000620124.03895.3A  1
2020 Gretchen C, Bayir H, Kochanek P, Kim-Campbell N. 202: Hyperoxia And Severe Hemolysis In Pediatric Cardiopulmonary Bypass Critical Care Medicine. 48: 83. DOI: 10.1097/01.Ccm.0000619164.46450.Db  1
2020 Munjal N, Clark R, Simon D, Kochanek P, Horvat C. 38: Machine Learning Predicting Mortality And Morbidity In Children With Neurologic Injury In The Picu Critical Care Medicine. 48: 19. DOI: 10.1097/01.Ccm.0000618652.25630.B6  1
2020 Zusman BE, Kochanek PM, Jha RM. Cerebral Edema in Traumatic Brain Injury: a Historical Framework for Current Therapy Current Treatment Options in Neurology. 22. DOI: 10.1007/S11940-020-0614-X  1
2019 Janata A, Magnet IA, Schreiber KL, Wilson CD, Stezoski JP, Janesko-Feldman K, Kochanek PM, Drabek T. Minocycline fails to improve neurologic and histologic outcome after ventricular fibrillation cardiac arrest in rats. World Journal of Critical Care Medicine. 8: 106-119. PMID 31853446 DOI: 10.5492/Wjccm.V8.I7.106  1
2019 Lumba-Brown A, Totten A, Kochanek PM. Emergency Department Implementation of the Brain Trauma Foundation's Pediatric Severe Brain Injury Guideline Recommendations. Pediatric Emergency Care. PMID 31804428 DOI: 10.1097/Pec.0000000000001903  0.01
2019 Kochanek PM, Grenvik AN, Tasker RC, Carney N, Totten AM, Adelson PD, Selden NR, Davis-O'Reilly C, Hart EL, Bell MJ, Bratton SL, Grant GA, Kissoon N, Reuter-Rice KE, Vavilala MS, et al. The authors reply. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 20: 1105-1107. PMID 31688689 DOI: 10.1097/PCC.0000000000002095  1
2019 Jackson TC, Janesko-Feldman K, Carlson SW, Kotermanski SE, Kochanek PM. Robust RBM3 and β-klotho expression in developing neurons in the human brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19878889. PMID 31566073 DOI: 10.1177/0271678X19878889  1
2019 Uray T, Empey PE, Drabek T, Stezoski JP, Janesko-Feldman K, Jackson T, Garman RH, Kim F, Kochanek PM, Dezfulian C. Nitrite pharmacokinetics, safety and efficacy after experimental ventricular fibrillation cardiac arrest. Nitric Oxide : Biology and Chemistry. PMID 31526855 DOI: 10.1016/J.Niox.2019.09.003  1
2019 Bell MJ, Kochanek PM. International traumatic brain injury research: an annus mirabilis? The Lancet. Neurology. 18: 904-905. PMID 31526746 DOI: 10.1016/S1474-4422(19)30289-3  1
2019 Pang D, Wu YL, Alcamo AM, Cummings J, Di Caro V, Walko T, Hsue V, Clark RSB, Panigrahy A, Kochanek PM, Aneja RK. Early Axonal Injury and Delayed Cytotoxic Cerebral Edema are Associated With Microglial Activation in a Mouse Model of Sepsis. Shock (Augusta, Ga.). PMID 31513049 DOI: 10.1097/Shk.0000000000001446  1
2019 Horvat CM, Ogoe H, Kantawala S, Au AK, Fink EL, Yablonsky E, Kochanek PM, Suresh S, Clark RSB. Development and Performance of Electronic Pediatric Risk of Mortality and Pediatric Logistic Organ Dysfunction-2 Automated Acuity Scores. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 20: e372-e379. PMID 31397827 DOI: 10.1097/Pcc.0000000000001998  1
2019 Horvat CM, Martin B, Wu L, Fabio A, Empey PE, Hagos F, Bigelow S, Kantawala S, Au AK, Kochanek PM, Clark RSB. Opioid e-prescribing trends at discharge in a large pediatric health system. Journal of Opioid Management. 15: 119-127. PMID 31343713 DOI: 10.5055/Jom.2019.0493  1
2019 Kim-Campbell N, Gretchen C, Ritov VB, Kochanek PM, Balasubramani GK, Kenny E, Sharma M, Viegas M, Callaway C, Kagan VE, Bayír H. Bioactive Oxylipins in Infants and Children With Congenital Heart Disease Undergoing Pediatric Cardiopulmonary Bypass. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 31305328 DOI: 10.1097/Pcc.0000000000002036  1
2019 Hagos FT, Horvat CM, Au AK, Conley YP, Li L, Poloyac SM, Kochanek PM, Clark RSB, Empey PE. Factors Contributing to Fentanyl Pharmacokinetic Variability Among Diagnostically Diverse Critically Ill Children. Clinical Pharmacokinetics. PMID 31168770 DOI: 10.1007/S40262-019-00773-1  1
2019 Pasek TA, Burns C, Treble-Barna A, Ortiz-Aguayo R, Kochanek PM, Houtrow AJ, Beers SR, Fink EL. Important Outcomes for Parents of Critically Ill Children. Critical Care Nurse. 39: 74-79. PMID 31154335 DOI: 10.4037/Ccn2019482  1
2019 Anthonymuthu TS, Kenny EM, Hier ZE, Clark RSB, Kochanek PM, Kagan VE, Bayır H. Detection of brain specific cardiolipins in plasma after experimental pediatric head injury. Experimental Neurology. PMID 30981805 DOI: 10.1016/J.Expneurol.2019.04.007  1
2019 Kochanek PM, Kudchadkar SR, Kissoon N. New Developments for Pediatric Critical Care Medicine in 2019 and Beyond. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 20: 311. PMID 30950986 DOI: 10.1097/Pcc.0000000000001885  1
2019 Treble-Barna A, Beers SR, Houtrow AJ, Ortiz-Aguayo R, Valenta C, Stanger M, Chrisman M, Orringer M, Smith CM, Pollon D, Duffett M, Choong K, Watson RS, Kochanek PM, Fink EL, et al. PICU-Based Rehabilitation and Outcomes Assessment: A Survey of Pediatric Critical Care Physicians. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 30946294 DOI: 10.1097/Pcc.0000000000001940  1
2019 Kochanek PM, Fink EL. Cooling via Trans-nasal High Flow Ambient Air: Does it Pass the Smell Test? Neurocritical Care. PMID 30903589 DOI: 10.1007/S12028-019-00701-Y  1
2019 Kochanek PM, Tasker RC, Carney N, Totten AM, Adelson PD, Selden NR, Davis-O'Reilly C, Hart EL, Bell MJ, Bratton SL, Grant GA, Kissoon N, Reuter-Rice KE, Vavilala MS, Wainwright MS. Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines, Executive Summary. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 20: 280-289. PMID 30830016 DOI: 10.1097/Pcc.0000000000001736  1
2019 Kochanek PM, Tasker RC, Bell MJ, Adelson PD, Carney N, Vavilala MS, Selden NR, Bratton SL, Grant GA, Kissoon N, Reuter-Rice KE, Wainwright MS. Management of Pediatric Severe Traumatic Brain Injury: 2019 Consensus and Guidelines-Based Algorithm for First and Second Tier Therapies. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 20: 269-279. PMID 30830015 DOI: 10.1097/Pcc.0000000000001737  1
2019 Kochanek PM, Tasker RC, Carney N, Totten AM, Adelson PD, Selden NR, Davis-O'Reilly C, Hart EL, Bell MJ, Bratton SL, Grant GA, Kissoon N, Reuter-Rice KE, Vavilala MS, Wainwright MS. Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 20: S1-S82. PMID 30829890 DOI: 10.1097/Pcc.0000000000001735  1
2019 Kochanek PM, Tasker RC, Carney N, Totten AM, Adelson PD, Selden NR, Davis-O'Reilly C, Hart EL, Bell MJ, Bratton SL, Grant GA, Kissoon N, Reuter-Rice KE, Vavilala MS, Wainwright MS. Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines, Executive Summary. Neurosurgery. PMID 30822776 DOI: 10.1093/Neuros/Nyz051  1
2019 Jackson TC, Kochanek PM. A New Vision for Therapeutic Hypothermia in the Era of Targeted Temperature Management: A Speculative Synthesis. Therapeutic Hypothermia and Temperature Management. PMID 30802174 DOI: 10.1089/Ther.2019.0001  1
2019 Hagos FT, Adams SM, Poloyac SM, Kochanek PM, Horvat CM, Clark RSB, Empey PE. Membrane transporters in traumatic brain injury: Pathological, pharmacotherapeutic, and developmental implications. Experimental Neurology. PMID 30797827 DOI: 10.1016/J.Expneurol.2019.02.011  1
2019 Jackson EK, Mi Z, Janesko-Feldman K, Jackson TC, Kochanek PM. 2',3'-cGMP Exists In Vivo and Comprises a 2',3'-cGMP-Guanosine Pathway. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 30789788 DOI: 10.1152/Ajpregu.00401.2018  1
2019 Fink EL, Beers SR, Houtrow AJ, Richichi R, Burns C, Doughty L, Ortiz-Aguayo R, Madurski CA, Valenta C, Chrisman M, Golightly L, Kiger M, Patrick C, Treble-Barna A, Pollon D, ... ... Kochanek P, et al. Early Protocolized Versus Usual Care Rehabilitation for Pediatric Neurocritical Care Patients: A Randomized Controlled Trial. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 30707210 DOI: 10.1097/Pcc.0000000000001881  1
2019 Chao H, Lin C, Zuo Q, Liu Y, Xiao M, Xu X, Li Z, Bao Z, Chen H, You Y, Kochanek PM, Yin H, Liu N, Kagan VE, Bayır H, et al. Cardiolipin-dependent mitophagy guides outcome after traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30626699 DOI: 10.1523/Jneurosci.3415-17.2018  1
2019 Soysal E, Horvat C, Simon D, Kochanek P, Clark R, Bayir H. 1811: Predictors Of Deterioration And Neurocritical Care Use In Pediatric Moderate Traumatic Brain Injury Critical Care Medicine. 47: 879. DOI: 10.1097/01.Ccm.0000552549.96071.1C  1
2019 Even K, Zuccoli G, Subramanian S, Kochanek P, Gaines B, Berger R, Fink E. 1807: Patterns Of Multiple Organ Dysfunction In Abusive Head Trauma Critical Care Medicine. 47: 877. DOI: 10.1097/01.Ccm.0000552545.75879.55  1
2019 Lanyi M, Elmer J, Kochanek P, Fink E. 1535: Child Survival Following Traumatic Versus Nontraumatic Out-Of-Hospital Cardiac Arrest Critical Care Medicine. 47: 743. DOI: 10.1097/01.Ccm.0000552278.10499.E0  1
2019 Wolf M, Manole M, New LA, Chen Y, Soysal E, Kochanek P, Bayir H, Clark R. 779: Ascorbate Deficiency Confers Resistance To Neurodegeneration In Pediatric Cardiac Arrest Critical Care Medicine. 47: 368. DOI: 10.1097/01.Ccm.0000551528.14476.4E  1
2018 Kenny EM, Fidan E, Yang Q, Anthonymuthu TS, New LA, Meyer EA, Wang H, Kochanek PM, Dixon CE, Kagan VE, Bayır H. Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury. Critical Care Medicine. PMID 30531185 DOI: 10.1097/Ccm.0000000000003555  1
2018 Kochanek PM, Jackson TC, Jha R, Clark RSB, Okonkwo DO, Bayir H, Poloyac SM, Wagner AK, Empey PE, Conley YP, Bell MJ, Kline AE, Bondi CO, Simon DW, Carlson SW, et al. Paths to successful translation of new therapies for severe TBI in the golden age of traumatic brain injury research: A Pittsburgh vision. Journal of Neurotrauma. PMID 30520681 DOI: 10.1089/Neu.2018.6203  1
2018 Jha RM, Desai SM, Zusman BE, Koleck TA, Puccio AM, Okonkwo DO, Park SY, Shutter L, Kochanek PM, Conley YP. Downstream TRPM4 Polymorphisms are associated with Intracranial Hypertension and Statistically Interact with ABCC8 Polymorphisms in a Prospective Cohort of Severe Traumatic Brain Injury. Journal of Neurotrauma. PMID 30484364 DOI: 10.1089/Neu.2018.6124  1
2018 Jha RM, Kochanek PM. A Precision Medicine Approach to Cerebral Edema and Intracranial Hypertension after Severe Traumatic Brain Injury: Quo Vadis? Current Neurology and Neuroscience Reports. 18: 105. PMID 30406315 DOI: 10.1007/S11910-018-0912-9  1
2018 Jackson TC, Kotermanski SE, Kochanek PM. Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain. Developmental Neuroscience. 1-12. PMID 30399610 DOI: 10.1159/000493637  1
2018 Jackson TC, Kotermanski SE, Kochanek PM, Jackson EK. Oxidative Stress Induces Release of 2'-AMP from Microglia. Brain Research. PMID 30395838 DOI: 10.1016/J.Brainres.2018.11.002  1
2018 Wallisch JS, Janesko-Feldman K, Alexander H, Jha RM, Farr GW, McGuirk PR, Kline AE, Jackson TC, Pelletier MF, Clark RSB, Kochanek PM, Manole MD. The aquaporin-4 inhibitor AER-271 blocks acute cerebral edema and improves early outcome in a pediatric model of asphyxial cardiac arrest. Pediatric Research. PMID 30367162 DOI: 10.1038/S41390-018-0215-5  1
2018 Wolf MS, Chen Y, Simon DW, Alexander H, Ross M, Gibson GA, Manole MD, Bayır H, Kochanek PM, Clark RSB. Quantitative and Qualitative Assessment of Glymphatic Flux Using Evans Blue Albumin. Journal of Neuroscience Methods. PMID 30292824 DOI: 10.1016/J.Jneumeth.2018.09.031  1
2018 Kochanek PM, Kissoon N, Kudchadkar SR. Pediatric Critical Care Medicine: Serving Our Missions While Maintaining Excellence. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 19: 915-916. PMID 30281564 DOI: 10.1097/Pcc.0000000000001711  1
2018 Kochanek PM, Jackson TC, Fink EL. Duration of therapeutic hypothermia or targeted temperature management in pediatric cardiac arrest: Seeing through the ice. Resuscitation. PMID 30278203 DOI: 10.1016/J.Resuscitation.2018.09.025  1
2018 Kochanek PM. A Big Loss for Our Field, But an Inspiration for Passion at the Bedside. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 19: 799. PMID 30180124 DOI: 10.1097/Pcc.0000000000001663  0.01
2018 Kochanek PM, Dixon CE, Mondello S, Wang KKK, Lafrenaye A, Bramlett HM, Dietrich WD, Hayes RL, Shear DA, Gilsdorf JS, Catania M, Poloyac SM, Empey PE, Jackson TC, Povlishock JT. Multi-Center Pre-clinical Consortia to Enhance Translation of Therapies and Biomarkers for Traumatic Brain Injury: Operation Brain Trauma Therapy and Beyond. Frontiers in Neurology. 9: 640. PMID 30131759 DOI: 10.3389/Fneur.2018.00640  1
2018 Jha RM, Elmer J, Zusman BE, Desai S, Puccio AM, Okonkwo DO, Park SY, Shutter LA, Wallisch JS, Conley YP, Kochanek PM. Intracranial Pressure Trajectories: A Novel Approach to Informing Severe Traumatic Brain Injury Phenotypes. Critical Care Medicine. PMID 30119071 DOI: 10.1097/Ccm.0000000000003361  1
2018 Jha RM, Kochanek PM, Simard JM. Pathophysiology and treatment of cerebral edema in traumatic brain injury. Neuropharmacology. PMID 30086289 DOI: 10.1016/J.Neuropharm.2018.08.004  1
2018 Aneja RK, Alcamo A, Cummings JL, Vagni VA, Janesko-Feldman KL, Wang Q, Dixon CE, Billiar T, Kochanek PM. Lack of Benefit on Brain Edema, Blood-Brain Barrier Permeability or Cognitive Outcome in Global, Inducible HMGB1 Knockout Mice despite Tissue Sparing after Experimental Traumatic Brain Injury. Journal of Neurotrauma. PMID 30045665 DOI: 10.1089/Neu.2018.5664  1
2018 Yang Z, Zhu T, Mondello S, Akel M, Wong AT, Kothari IM, Lin F, Shear DA, Gilsdorf J, Leung LY, Bramlett HM, Dixon CE, Dietrich WD, Hayes RL, Povlishock J, ... ... Kochanek PM, et al. Serum-based phospho-neurofilament-heavy protein as theranostic biomarker in three models of traumatic brain injury: an Operation Brain Trauma Therapy (OBTT) study. Journal of Neurotrauma. PMID 29987972 DOI: 10.1089/Neu.2017.5586  1
2018 Rakholia MV, Kumar RG, Oh BM, Ranganathan PR, Berga S, Kochanek PM, Wagner AK. Systemic estrone production and injury induced sex hormone steroidogenesis after severe traumatic brain injury: a prognostic indicator of TBI-related mortality. Journal of Neurotrauma. PMID 29947289 DOI: 10.1089/Neu.2018.5782  1
2018 Morrison AM, Houtrow A, Zullo J, Kochanek PM, Vetterly C, Fink EL. Neurostimulant prescribing patterns in children admitted to the ICU after traumatic brain injury. Journal of Neurotrauma. PMID 29756534 DOI: 10.1089/Neu.2017.5575  1
2018 DeWitt D, Hawkins BE, Dixon CE, Kochanek PM, Armstead WM, Bass C', Bramlett HM, Büki A, Dietrich WD, Ferguson AR, Hall ED, Hayes RL, Hinds Ii CSR, LaPlaca M, Long J, et al. Preclinical Testing of Therapies for Traumatic Brain Injury. Journal of Neurotrauma. PMID 29756522 DOI: 10.1089/Neu.2018.5778  1
2018 Hagos FT, Empey PE, Wang P, Ma X, Poloyac SM, Bayır H, Kochanek PM, Bell MJ, Clark RSB. Exploratory Application of Neuropharmacometabolomics in Severe Childhood Traumatic Brain Injury. Critical Care Medicine. PMID 29742587 DOI: 10.1097/Ccm.0000000000003203  1
2018 Fidan E, Foley LM, New LA, Alexander H, Kochanek PM, Hitchens TK, Bayır H. Metabolic and Structural Imaging at 7 Tesla After Repetitive Mild Traumatic Brain Injury in Immature Rats. Asn Neuro. 10: 1759091418770543. PMID 29741097 DOI: 10.1177/1759091418770543  1
2018 Jackson TC, Dixon CE, Janesko-Feldman K, Vagni V, Kotermanski SE, Jackson EK, Kochanek PM. Acute Physiology and Neurologic Outcomes after Brain Injury in SCOP/PHLPP1 KO Mice. Scientific Reports. 8: 7158. PMID 29739983 DOI: 10.1038/S41598-018-25371-2  1
2018 Wolf MS, Bayır H, Kochanek PM, Clark RSB. The role of autophagy in acute brain injury: A state of flux? Neurobiology of Disease. PMID 29704549 DOI: 10.1016/J.Nbd.2018.04.018  1
2018 Jha RM, Koleck TA, Puccio AM, Okonkwo DO, Park SY, Zusman BE, Clark RSB, Shutter LA, Wallisch JS, Empey PE, Kochanek PM, Conley YP. Regionally clustered polymorphisms in a prospective cohort predict cerebral oedema and outcome in severe traumatic brain injury. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 29674479 DOI: 10.1136/Jnnp-2017-317741  1
2018 Fink EL, von Saint Andre-von Arnim A, Kumar R, Wilson PT, Bacha T, Aklilu AT, Teklemariam TL, Hooli S, Tuyisenge L, Otupiri E, Fabio A, Gianakas J, Kochanek PM, Angus DC, Tasker RC, et al. Traumatic Brain Injury and Infectious Encephalopathy in Children From Four Resource-Limited Settings in Africa. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 29664874 DOI: 10.1097/Pcc.0000000000001554  1
2018 Jha R, Molyneaux BJ, Jackson TC, Wallisch J, Park SY, Poloyac SM, Vagni VA, Janesko-Feldman KL, Hoshitsuki K, Minnigh MB, Kochanek PM. Glibenclamide produces region-dependent effects on cerebral edema in a combined injury model of traumatic brain injury and hemorrhagic shock in mice. Journal of Neurotrauma. PMID 29648981 DOI: 10.1089/Neu.2016.4696  1
2018 Kochanek PM, Bramlett HM, Dixon CE, Dietrich WD, Mondello S, Wang KKW, Hayes RL, Lafrenaye A, Povlishock JT, Tortella FC, Poloyac SM, Empey P, Shear DA. Operation Brain Trauma Therapy: 2016 Update. Military Medicine. 183: 303-312. PMID 29635589 DOI: 10.1093/Milmed/Usx184  1
2018 Horvat CM, Ismail HM, Au AK, Garibaldi L, Siripong N, Kantawala S, Aneja RK, Hupp DS, Kochanek PM, Clark RSB. Presenting Predictors and Temporal Trends of Treatment-Related Outcomes in Diabetic Ketoacidosis. Pediatric Diabetes. PMID 29573523 DOI: 10.1111/Pedi.12663  1
2018 Uray T, Lamade A, Elmer J, Drabek T, Stezoski JP, Missé A, Janesko-Feldman K, Garman RH, Chen N, Kochanek PM, Dezfulian C. Phenotyping Cardiac Arrest: Bench and Bedside Characterization of Brain and Heart Injury Based on Etiology. Critical Care Medicine. PMID 29533310 DOI: 10.1097/Ccm.0000000000003070  1
2018 Kochanek PM. A Special 50-Year Perspective on Our Field. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 29424791 DOI: 10.1097/Pcc.0000000000001494  0.01
2018 Meinert E, Bell MJ, Buttram S, Kochanek PM, Balasubramani GK, Wisniewski SR, Adelson PD. Initiating Nutritional Support Before 72 Hours Is Associated With Favorable Outcome After Severe Traumatic Brain Injury in Children: A Secondary Analysis of a Randomized, Controlled Trial of Therapeutic Hypothermia. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 29370008 DOI: 10.1097/Pcc.0000000000001471  1
2018 Simon D, McGeachy M, Raphael I, Vagni V, Kochanek P, Bayir H, Clark R. 1571: Role Of Il-17 After Traumatic Brain Injury In Adult Mice Critical Care Medicine. 46: 770. DOI: 10.1097/01.Ccm.0000529572.79638.24  1
2018 Woods K, Horvat C, Kantawala S, Kochanek P, Clark R, Au A. 823: Intracranial Pressure Thresholds Associated With Mortality In Pediatric Neurocritical Care Patients Critical Care Medicine. 46: 396. DOI: 10.1097/01.Ccm.0000528832.82636.4C  1
2017 Jackson TC, Kotermanski SE, Jackson EK, Kochanek PM. BrainPhys® increases neurofilament levels in CNS cultures, and facilitates investigation of axonal damage after a mechanical stretch-injury in vitro. Experimental Neurology. 300: 232-246. PMID 29199132 DOI: 10.1016/J.Expneurol.2017.11.013  1
2017 Li L, Poloyac SM, Waltkins SC, St Croix CM, Alexander H, Gibson GA, Loughran PA, Kirisci L, Clark RS, Kochanek PM, Vazquez AL, Manole MD. Cerebral microcirculatory alterations and the no-reflow phenomenon in vivo after experimental pediatric cardiac arrest. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17744717. PMID 29192562 DOI: 10.1177/0271678X17744717  1
2017 Kochanek PM, Wallisch JS, Bayır H, Clark RSB. Pre-clinical models in pediatric traumatic brain injury-challenges and lessons learned. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. 33: 1693-1701. PMID 29149385 DOI: 10.1007/S00381-017-3474-2  1
2017 Kochanek PM, Kissoon N. Breaking Into the Top Ten. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 18: 913-914. PMID 28976460 DOI: 10.1097/Pcc.0000000000001297  1
2017 Adams SM, Conley YP, Wagner AK, Jha RM, Clark RS, Poloyac SM, Kochanek PM, Empey PE. The pharmacogenomics of severe traumatic brain injury. Pharmacogenomics. PMID 28975867 DOI: 10.2217/Pgs-2017-0073  1
2017 Kim-Campbell N, Gretchen C, Callaway C, Felmet K, Kochanek PM, Maul T, Wearden P, Sharma M, Viegas M, Munoz R, Gladwin MT, Bayir H. Cell-Free Plasma Hemoglobin and Male Gender Are Risk Factors for Acute Kidney Injury in Low Risk Children Undergoing Cardiopulmonary Bypass. Critical Care Medicine. PMID 28863013 DOI: 10.1097/Ccm.0000000000002703  1
2017 Horvat CM, Kochanek PM. Big Data Not Yet Big Enough to Determine the Influence of Intracranial Pressure Monitoring on Outcome in Children With Severe Traumatic Brain Injury. Jama Pediatrics. PMID 28846750 DOI: 10.1001/Jamapediatrics.2017.2390  1
2017 Jackson TC, Kotermanski SE, Kochanek PM. Whole-Transcriptome Microarray Analysis Reveals Regulation of Rab4 by RBM5 in Neurons. Neuroscience. PMID 28818525 DOI: 10.1016/J.Neuroscience.2017.08.014  1
2017 Kochanek PM, Jackson TC. Therapeutic Hypothermia and Targeted Temperature Management With or Without the "Cold Stress" Response. Therapeutic Hypothermia and Temperature Management. PMID 28800291 DOI: 10.1089/ther.2017.0030  1
2017 Simon DW, McGeachy MJ, Bayır H, Clark RSB, Loane DJ, Kochanek PM. The far-reaching scope of neuroinflammation after traumatic brain injury. Nature Reviews. Neurology. PMID 28776601 DOI: 10.1038/nrneurol.2017.116  1
2017 Bosetti F, Koenig JI, Ayata C, Back SA, Becker K, Broderick JP, Carmichael ST, Cho S, Cipolla MJ, Corbett D, Corriveau RA, Cramer SC, Ferguson AR, Finklestein SP, Ford BD, ... ... Kochanek PM, et al. Translational Stroke Research: Vision and Opportunities. Stroke. PMID 28751554 DOI: 10.1161/Strokeaha.117.017112  0.01
2017 Adams SM, Conley YP, Ren D, Okonkwo DO, Puccio A, Dixon CE, Clark RS, Kochanek PM, Empey PE. ABCG2 c.421C>A is Associated with Outcomes Following Severe Traumatic Brain Injury. Journal of Neurotrauma. PMID 28747144 DOI: 10.1089/neu.2017.5000  1
2017 Jha RM, Kochanek PM. Adding insight to injury: a new era in neurotrauma. The Lancet. Neurology. 16: 578-580. PMID 28721915 DOI: 10.1016/S1474-4422(17)30225-9  1
2017 Simon DW, Aneja RK, Alexander H, Bell MJ, Bayir H, Kochanek PM, Clark RSB. Minocycline Attenuates High Mobility Group Box 1 Translocation, Microglial Activation, and Thalamic Neurodegeneration after Traumatic Brain Injury in Postnatal Day 17 Rats. Journal of Neurotrauma. PMID 28699371 DOI: 10.1089/neu.2017.5093  1
2017 Clark RSB, Empey PE, Bayır H, Rosario BL, Poloyac SM, Kochanek PM, Nolin TD, Au AK, Horvat CM, Wisniewski SR, Bell MJ. Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children. Plos One. 12: e0180280. PMID 28686657 DOI: 10.1371/Journal.Pone.0180280  1
2017 Middleton JW, Simons DJ, Simmons JW, Clark RSB, Kochanek PM, Shoykhet M. Long-Term Deficits in Cortical Circuit Function after Asphyxial Cardiac Arrest and Resuscitation in Developing Rats. Eneuro. 4. PMID 28674699 DOI: 10.1523/ENEURO.0319-16.2017  1
2017 Au AK, Bell MJ, Fink EL, Aneja RK, Kochanek PM, Clark RSB. Brain-Specific Serum Biomarkers Predict Neurological Morbidity in Diagnostically Diverse Pediatric Intensive Care Unit Patients. Neurocritical Care. PMID 28612133 DOI: 10.1007/S12028-017-0414-7  1
2017 Kochanek PM, Bayir H. Titrating the dose of oxygen after severe traumatic brain injury in the era of precision medicine. Journal of Neurotrauma. PMID 28537530 DOI: 10.1089/Neu.2017.5159  1
2017 Kochanek PM, Kudchadkar SR, Kissoon N. Guiding Pediatric Critical Care Medicine Toward a Bigger "Impression" in 2017 and Beyond. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 18: 403-404. PMID 28475530 DOI: 10.1097/Pcc.0000000000001178  1
2017 Nora GJ, Harun R, Fine DF, Hutchison D, Grobart AC, Stezoski JP, Munoz M, Kochanek PM, Leak RK, Drabek T, Wagner AK. Ventricular Fibrillation Cardiac Arrest Produces a Chronic Striatal Hyperdopaminergic State that is Worsened by Methylphenidate Treatment. Journal of Neurochemistry. PMID 28445595 DOI: 10.1111/Jnc.14058  1
2017 Miller Ferguson N, Sarnaik A, Miles D, Shafi N, Peters MJ, Truemper E, Vavilala MS, Bell MJ, Wisniewski SR, Luther JF, Hartman AL, Kochanek PM. Abusive Head Trauma and Mortality-An Analysis From an International Comparative Effectiveness Study of Children With Severe Traumatic Brain Injury. Critical Care Medicine. PMID 28430697 DOI: 10.1097/Ccm.0000000000002378  1
2017 Berger RP, Pak BJ, Kolesnikova MD, Fromkin J, Saladino R, Herman BE, Pierce MC, Englert D, Smith PT, Kochanek PM. Derivation and Validation of a Serum Biomarker Panel to Identify Infants With Acute Intracranial Hemorrhage. Jama Pediatrics. e170429. PMID 28395008 DOI: 10.1001/Jamapediatrics.2017.0429  1
2017 Horvat CM, Au AK, Conley YL, Kochanek PM, Li L, Poloyac SL, Empey PE, Clark RS. ABCB1 genotype is associated with fentanyl requirements in critically Ill children. Pediatric Research. PMID 28388599 DOI: 10.1038/Pr.2017.103  1
2017 Anthonymuthu TS, Kenny EM, Amoscato AA, Lewis J, Kochanek PM, Kagan VE, Bayır H. Global assessment of oxidized free fatty acids in brain reveals an enzymatic predominance to oxidative signaling after trauma. Biochimica Et Biophysica Acta. PMID 28347845 DOI: 10.1016/J.Bbadis.2017.03.015  1
2017 Cui LR, LaPorte M, Civitello M, Stanger M, Orringer M, Casey F, Kuch BA, Beers SR, Valenta CA, Kochanek PM, Houtrow AJ, Fink EL. Physical and occupational therapy utilization in a pediatric intensive care unit. Journal of Critical Care. 40: 15-20. PMID 28297684 DOI: 10.1016/J.Jcrc.2017.03.003  1
2017 Jackson EK, Kotermanski SE, Menshikova EV, Dubey RK, Jackson TC, Kochanek PM. Adenosine Production by Brain Cells. Journal of Neurochemistry. PMID 28294336 DOI: 10.1111/Jnc.14018  1
2017 Wallisch JS, Kochanek PM. A "Metamorphosis" in Our Approach to Treatment Is Not Likely to Result From a Meta-Analysis of the Use of Therapeutic Hypothermia in Severe Traumatic Brain Injury. Critical Care Medicine. 45: 744-745. PMID 28291098 DOI: 10.1097/Ccm.0000000000002240  1
2017 Fink EL, Kochanek PM, Tasker RC, Beca J, Bell MJ, Clark RS, Hutchison J, Vavilala MS, Fabio A, Angus DC, Watson RS. International Survey of Critically Ill Children With Acute Neurologic Insults: The Prevalence of Acute Critical Neurological Disease in Children: A Global Epidemiological Assessment Study. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 28207570 DOI: 10.1097/Pcc.0000000000001093  1
2017 Simon DW, McGeachy MJ, Bayır H, Clark RS, Loane DJ, Kochanek PM. The far-reaching scope of neuroinflammation after traumatic brain injury. Nature Reviews. Neurology. PMID 28186177 DOI: 10.1038/Nrneurol.2017.13  1
2017 Wallisch JS, Simon DW, Bayır H, Bell MJ, Kochanek PM, Clark RS. Cerebrospinal Fluid NLRP3 is Increased After Severe Traumatic Brain Injury in Infants and Children. Neurocritical Care. PMID 28181102 DOI: 10.1007/S12028-017-0378-7  1
2017 Griffith B, Kochanek P, Dezfulian C. The benefits of youth are lost on the young cardiac arrest patient. F1000research. 6: 77. PMID 28163912 DOI: 10.12688/F1000Research.9316.1  1
2017 Kochanek PM, Jackson TC. The Brain and Hypothermia-From Aristotle to Targeted Temperature Management. Critical Care Medicine. 45: 305-310. PMID 28098626 DOI: 10.1097/Ccm.0000000000002182  1
2017 Fabio A, Gao S, Bell M, Kochanek P, Wisniewski S. 97 Gunshot wounds to the head: the epidemiology of severe paediatric firearm-related traumatic brain injuries Injury Prevention. 23. DOI: 10.1136/Injuryprev-2017-042560.97  1
2016 Au AK, Aneja RK, Bayır H, Bell MJ, Janesko-Feldman K, Kochanek PM, Clark RS. Autophagy Biomarkers Beclin 1 and p62 are Increased in Cerebrospinal Fluid after Traumatic Brain Injury. Neurocritical Care. PMID 28000126 DOI: 10.1007/S12028-016-0351-X  1
2016 Brockman EC, Jackson TC, Dixon CE, Bayir H, Clark R, Vagni VA, Janesko KL, Byrd C, Ma L, Hsia CJ, Kochanek PM. POLYNITROXYLATED PEGYLATED HEMOGLOBIN: A NOVEL, SMALL VOLUME THERAPEUTIC FOR TRAUMATIC BRAIN INJURY RESUSCITATION: COMPARISON TO WHOLE BLOOD AND DOSE RESPONSE EVALUATION. Journal of Neurotrauma. PMID 27869558 DOI: 10.1089/neu.2016.4656  1
2016 Blennow K, Brody DL, Kochanek PM, Levin H, McKee A, Ribbers GM, Yaffe K, Zetterberg H. Traumatic brain injuries. Nature Reviews. Disease Primers. 2: 16084. PMID 27853132 DOI: 10.1038/nrdp.2016.84  0.01
2016 Ferguson NM, Kochanek P, Bell M, Wisniewski S, Sarnaik A, Miles D, Shafi N, Truemper E. 1536: ABUSIVE HEAD TRAUMA AND MORTALITY: AN ANALYSIS FROM AN INTERNATIONAL COMPARATIVE EFFECTIVENESS STUDY. Critical Care Medicine. 44: 459. PMID 27851172 DOI: 10.1097/01.Ccm.0000510210.35820.5C  1
2016 Woods K, Au A, Kochanek P, Bell M, Clark R. 775: SERUM BIOMARKER-BASED MODELS TO PREDICT INTRACRANIAL PRESSURE IN PEDIATRIC TRAUMATIC BRAIN INJURY. Critical Care Medicine. 44: 270. PMID 27850413 DOI: 10.1097/01.Ccm.0000509451.19080.45  1
2016 Simon D, Aneja R, New L, Vagni V, Bayir H, Morowitz M, Kochanek P, Clark R. 743: ACUTE INFLAMMATORY RESPONSE TO TRAUMATIC BRAIN INJURY IS AFFECTED BY MODULATORS OF GUT MICROBIOTA. Critical Care Medicine. 44: 262. PMID 27850381 DOI: 10.1097/01.Ccm.0000509419.49574.44  1
2016 Kenny E, Yang Q, Fidan E, Ann New L, Anthonymuthu TS, Kochanek P, Kagan V, Bayir H. 740: INHIBITION OF FERROPTOSIS AS A NEUROPROTECTIVE STRATEGY FOLLOWING TRAUMATIC BRAIN INJURY. Critical Care Medicine. 44: 261. PMID 27850378 DOI: 10.1097/01.Ccm.0000509416.82747.8D  1
2016 Jha R, Puccio A, Okonkwo D, Zusman B, Wallisch J, Shutter L, Kochanek P, Conley Y. 738: ABCC8 TAG SINGLE NUCLEOTIDE POLYMORPHISMS CORRELATE WITH EDEMA AND OUTCOME IN TRAUMATIC BRAIN INJURY. Critical Care Medicine. 44: 260. PMID 27850376 DOI: 10.1097/01.Ccm.0000509414.75123.25  1
2016 Wolf M, Chen Y, Simon D, Manole M, New L, Alexander H, Kochanek P, Clark R. 731: ASSESSMENT OF GLYMPHATIC FLUX IN A PEDIATRIC RODENT MODEL OF INTRACRANIAL HYPERTENSION. Critical Care Medicine. 44: 259. PMID 27850369 DOI: 10.1097/01.Ccm.0000509407.59876.5B  1
2016 Horvat C, Bell M, Wisniewski S, Balasubramani G, Kochanek P, Beers S, Brown SD, Adelson P. 726: POST-RESUSCITATION GCS IS ASSOCIATED WITH OUTCOME IN PEDIATRIC SEVERE TRAUMATIC BRAIN INJURY. Critical Care Medicine. 44: 257. PMID 27850364 DOI: 10.1097/01.Ccm.0000509402.91263.A4  1
2016 Pang D, Wu Y, Cummings J, Panigrahy A, Clark R, Kochanek P, Aneja R. 721: MICROGLIAL ACTIVATION CORRELATES WITH CYTOTOXIC EDEMA IN A MURINE MODEL OF SEPSIS. Critical Care Medicine. 44: 256. PMID 27850359 DOI: 10.1097/01.Ccm.0000509397.04726.5D  1
2016 Wallisch J, Jha R, Farr G, McGuirk P, Pelletier M, Jackson T, Kochanek P, Manole M. 718: AQUAPORIN-4 INHIBITOR AER-271 BLOCKS EARLY CEREBRAL EDEMA IN PEDIATRIC RAT ASPHYXIAL CARDIAC ARREST. Critical Care Medicine. 44: 255. PMID 27850356 DOI: 10.1097/01.Ccm.0000509394.12349.6B  1
2016 Jha RM, Puccio AM, Chou SH, Chang CH, Wallisch JS, Molyneaux BJ, Zusman BE, Shutter LA, Poloyac SM, Janesko-Feldman KL, Okonkwo DO, Kochanek PM. Sulfonylurea Receptor-1: A Novel Biomarker for Cerebral Edema in Severe Traumatic Brain Injury. Critical Care Medicine. PMID 27845954 DOI: 10.1097/Ccm.0000000000002079  1
2016 Tamburro RF, Jenkins TL, Kochanek PM. Strategic Planning for Research in Pediatric Critical Care. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 17: e539-e542. PMID 27679964 DOI: 10.1097/Pcc.0000000000000946  0.01
2016 Jha RM, Puccio AM, Okonkwo DO, Zusman BE, Park SY, Wallisch J, Empey PE, Shutter LA, Clark RS, Kochanek PM, Conley YP. ABCC8 Single Nucleotide Polymorphisms are Associated with Cerebral Edema in Severe TBI. Neurocritical Care. PMID 27677908 DOI: 10.1007/S12028-016-0309-Z  1
2016 Foley LM, Clark RS, Vazquez AL, Hitchens TK, Alexander H, Ho C, Kochanek PM, Manole MD. Enduring Disturbances in Regional Cerebral Blood Flow and Brain Oxygenation at 24 Hours after Asphyxial Cardiac Arrest in Developing Rats. Pediatric Research. PMID 27636898 DOI: 10.1038/Pr.2016.175  1
2016 Anderson KB, Poloyac SM, Kochanek PM, Empey PE. Effect of Hypothermia and Targeted Temperature Management on Drug Disposition and Response Following Cardiac Arrest: A Comprehensive Review of Preclinical and Clinical Investigations. Therapeutic Hypothermia and Temperature Management. PMID 27622966 DOI: 10.1089/ther.2016.0003  1
2016 Simon DW, Vagni VM, Kochanek PM, Clark RS. Combined Neurotrauma Models: Experimental Models Combining Traumatic Brain Injury and Secondary Insults. Methods in Molecular Biology (Clifton, N.J.). 1462: 393-411. PMID 27604730 DOI: 10.1007/978-1-4939-3816-2_22  1
2016 Sparvero LJ, Amoscato AA, Fink AB, Anthonymuthu T, New LE, Kochanek PM, Watkins S, Kagan VE, Bayır H. Imaging Mass Spectrometry Reveals Loss of Polyunsaturated Cardiolipins in the Cortical Contusion, Hippocampus and Thalamus after Traumatic Brain Injury. Journal of Neurochemistry. PMID 27591733 DOI: 10.1111/Jnc.13840  1
2016 Dezfulian C, Kenny E, Lamade A, Misse A, Krehel N, St Croix C, Kelley EE, Jackson TC, Uray T, Rackley J, Kochanek PM, Clark RS, Bayir H. Mechanistic characterization of nitrite-mediated neuroprotection after experimental cardiac arrest. Journal of Neurochemistry. PMID 27507435 DOI: 10.1111/Jnc.13764  1
2016 Kochanek PM. Pediatric Critical Care Medicine: Accomplishments and Important New Initiatives. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 17: 709. PMID 27500611 DOI: 10.1097/Pcc.0000000000000925  0.01
2016 Kochanek P, Kitagawa RS, Batchelor P, Thoresen M. Central Nervous System Injury and Temperature Management. Therapeutic Hypothermia and Temperature Management. 6: 112-115. PMID 27447753 DOI: 10.1089/Ther.2016.29014.Pjk  1
2016 Berger RP, Fromkin J, Herman B, Pierce MC, Saladino RA, Flom L, Tyler-Kabara EC, McGinn T, Richichi R, Kochanek PM. Validation of the Pittsburgh Infant Brain Injury Score for Abusive Head Trauma. Pediatrics. PMID 27338699 DOI: 10.1542/Peds.2015-3756  1
2016 Mondello S, Kobeissy F, Vestri A, Hayes RL, Kochanek PM, Berger RP. Serum Concentrations of Ubiquitin C-Terminal Hydrolase-L1 and Glial Fibrillary Acidic Protein after Pediatric Traumatic Brain Injury. Scientific Reports. 6: 28203. PMID 27319802 DOI: 10.1038/Srep28203  1
2016 Hagos FT, Daood MJ, Ocque JA, Nolin TD, Bayir H, Poloyac SM, Kochanek PM, Clark RS, Empey PE. Probenecid, an organic anion transporter 1 and 3 inhibitor, increases plasma and brain exposure of N-acetylcysteine. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-8. PMID 27278858 DOI: 10.1080/00498254.2016.1187777  1
2016 Batchelor P, Dietrich WD, Kochanek PM, Lundbye J. Secondary Changes After Injury and Temperature. Therapeutic Hypothermia and Temperature Management. PMID 27249580 DOI: 10.1089/Ther.2016.29013.Pjb  1
2016 Miller Ferguson N, Shein SL, Kochanek PM, Luther J, Wisniewski SR, Clark RS, Tyler-Kabara EC, Adelson PD, Bell MJ. Intracranial Hypertension and Cerebral Hypoperfusion in Children With Severe Traumatic Brain Injury: Thresholds and Burden in Accidental and Abusive Insults. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 27028792 DOI: 10.1097/Pcc.0000000000000709  1
2016 Wiley CA, Bissel SJ, Lesniak A, Dixon CE, Franks J, Stolz DB, Sun M, Wang G, Switzer Iii RC, Kochanek PM, Murdoch GH. Ultrastructure of diaschisis lesions following traumatic brain injury. Journal of Neurotrauma. PMID 26914973 DOI: 10.1089/Neu.2015.4272  1
2016 Fink EL, Berger RP, Clark RS, Watson RS, Angus DC, Panigrahy A, Richichi R, Callaway CW, Bell MJ, Mondello S, Hayes RL, Kochanek PM. Exploratory Study of Serum Ubiquitin Carboxyl-Terminal Esterase L1 and Glial Fibrillary Acidic Protein for Outcome Prognostication after Pediatric Cardiac Arrest. Resuscitation. PMID 26855294 DOI: 10.1016/J.Resuscitation.2016.01.024  1
2016 Du L, Empey P, Ji J, Chao H, Kochanek PM, Bayir H, Clark R. Probenecid and N-acetylcysteine Prevent Loss of Intracellular Glutathione and Inhibit Neuronal Death after Mechanical Stretch Injury In Vitro. Journal of Neurotrauma. PMID 26830358 DOI: 10.1089/Neu.2015.4342  1
2016 Jackson EK, Boison D, Schwarzschild MA, Kochanek PM. Purines: forgotten mediators in traumatic brain injury. Journal of Neurochemistry. 137: 142-53. PMID 26809224 DOI: 10.1111/Jnc.13551  1
2016 Kochanek PM. Pediatric Critical Care Medicine 2016: Growth and Further Specialization. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 17: 1. PMID 26731318 DOI: 10.1097/Pcc.0000000000000579  0.01
2016 Kochanek PM, Clark RS. Traumatic brain injury research highlights in 2015. The Lancet. Neurology. 15: 13-5. PMID 26700899 DOI: 10.1016/S1474-4422(15)00339-7  1
2015 Kumar RG, Rubin JE, Berger RP, Kochanek PM, Wagner AK. Principal Components Derived from CSF Inflammatory Profiles Predict Outcome in Survivors after Severe Traumatic Brain Injury. Brain, Behavior, and Immunity. PMID 26705843 DOI: 10.1016/J.Bbi.2015.12.008  1
2015 Shein SL, Ferguson NM, Kochanek PM, Bayir H, Clark RS, Fink EL, Tyler-Kabara EC, Wisniewski SR, Tian Y, Balasubramani GK, Bell MJ. Effectiveness of Pharmacological Therapies for Intracranial Hypertension in Children With Severe Traumatic Brain Injury-Results From an Automated Data Collection System Time-Synched to Drug Administration. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 26673840 DOI: 10.1097/Pcc.0000000000000610  1
2015 Mondello S, Shear DA, Bramlett HM, Dixon CE, Schmid Maj KE, Dietrich WD, Wang KK, Hayes RL, Glushakova O, Catania M, Richieri S, Povlishock J, Tortella FC, Kochanek PM. Insight into Preclinical Models of Traumatic Brain Injury Using Circulating Brain Damage Biomarkers: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671651 DOI: 10.1089/Neu.2015.4132  1
2015 Browning M, Shear DA, Bramlett HM, Dixon CE, Mondello S, Schmid Maj KE, Poloyac SM, Dietrich WD, Hayes RL, Wang KK, Povlishock J, Tortella FC, Kochanek PM. Levetiracetam Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671550 DOI: 10.1089/Neu.2015.4131  1
2015 Kochanek PM, Bramlett HM, Shear DA, Dixon CE, Mondello S, Dietrich WD, Hayes RL, Wang KK, Poloyac SM, Empey P, Povlishock J, Mountney A, Browning M, Deng-Bryant Y, Yan HQ, et al. Synthesis of Findings, Current Investigations, and Future Directions: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671284 DOI: 10.1089/Neu.2015.4133  1
2015 Dixon CE, Bramlett HM, Dietrich WD, Shear DA, Yan HQ, Deng-Bryant Y, Mondello S, Wang KK, Hayes RL, Empey P, Povlishock J, Tortella FC, Kochanek PM. Cyclosporine Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671075 DOI: 10.1089/Neu.2015.4122  1
2015 Shear DA, Bramlett HM, Dixon CE, Dietrich WD, Deng-Bryant Y, Schmid Maj KE, Mondello S, Wang KK, Hayes RL, Povlishock J, Kochanek PM, Tortella FC. Nicotinamide Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26670792 DOI: 10.1089/Neu.2015.4115  1
2015 Bramlett HM, Dietrich WD, Dixon CE, Shear DA, Schmid Maj KE, Mondello S, Wang KK, Hayes RL, Povlishock J, Tortella FC, Kochanek PM. Erythropoietin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26670694 DOI: 10.1089/Neu.2015.4116  1
2015 Kochanek PM, Bayır H. Hidden Perils of the "Wild Blue Yonder" after Traumatic Brain Injury. Journal of Neurotrauma. PMID 26625357 DOI: 10.1089/Neu.2015.4329  1
2015 Jackson EK, Menshikova EV, Mi Z, Verrier JD, Bansal R, Janesko-Feldman K, Jackson TC, Kochanek PM. Renal 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase Is an Important Determinant of AKI Severity after Ischemia-Reperfusion. Journal of the American Society of Nephrology : Jasn. PMID 26574047 DOI: 10.1681/Asn.2015040397  1
2015 Pang D, Wu Y, Cummings J, Hsue V, Di Caro V, Clark R, Kochanek P, Aneja R. 1000: NEURORADIOLOGIC AND HISTOPATHOLOGIC CORRELATES OF BRAIN INJURY IN A MURINE MODEL OF SEPSIS. Critical Care Medicine. 43: 251-252. PMID 26570661 DOI: 10.1097/01.Ccm.0000474831.40412.35  1
2015 Jha R, Molyneaux B, Jackson T, Wallisch J, Vagni V, Poloyac S, Dixon C, Kochanek P. 491: GLIBENCLAMIDE REDUCES DIFFUSE CEREBRAL EDEMA IN A COMBINED MODEL OF TRAUMATIC BRAIN INJURY AND SHOCK. Critical Care Medicine. 43: 124. PMID 26570152 DOI: 10.1097/01.Ccm.0000474319.38132.1B  1
2015 Adams S, Cheng J, Diduch M, Daood M, Clark R, Kochanek P, Kline A, Empey P. 484: NEXT GENERATION GENE EXPRESSION ANALYSIS SHOWS DECREASED EXPRESSION OF TRANSPORTERS FOLLOWING TBI. Critical Care Medicine. 43: 122-123. PMID 26570145 DOI: 10.1097/01.Ccm.0000474312.22885.A5  1
2015 Fink E, Fabio A, Panigrahy A, Berger R, Clark R, Angus D, Bell M, Kochanek P. 186: EXPLORATORY STUDY OF DURATION OF HYPOTHERMIA FOR NEUROPROTECTION AFTER PEDIATRIC CARDIAC ARREST. Critical Care Medicine. 43: 48. PMID 26569847 DOI: 10.1097/01.Ccm.0000474014.10448.Bb  1
2015 Meinert E, Bell M, Adelson P, Buttram S, Kochanek P, Balasubramani G, Wisniewski S. 17: EARLY NUTRITIONAL SUPPORT IS ASSOCIATED WITH FAVORABLE OUTCOME IN PEDIATRIC TRAUMATIC BRAIN INJURY. Critical Care Medicine. 43: 5. PMID 26569678 DOI: 10.1097/01.Ccm.0000473845.82219.9B  1
2015 Byrd C, Wallisch J, Jha R, Vagni V, Wisniewski S, Ma L, Hsia C, Kochanek P. 12: POLYNITROXYLATED-PEGYLATED HEMOGLOBIN AS AN ULTRA-SMALL VOLUME RESUSCITATION THERAPY. Critical Care Medicine. 43: 3-4. PMID 26569673 DOI: 10.1097/01.Ccm.0000473840.00805.63  1
2015 Manchester LC, Lee V, Schmithorst V, Kochanek PM, Panigrahy A, Fink EL. Global and Regional Derangements of Cerebral Blood Flow and Diffusion Magnetic Resonance Imaging after Pediatric Cardiac Arrest. The Journal of Pediatrics. PMID 26561380 DOI: 10.1016/J.Jpeds.2015.10.003  1
2015 Mountney A, Bramlett HM, Dixon CE, Mondello S, Dietrich WD, Wang KK, Caudle KL, Empey P, Poloyac SM, Hayes RL, Povlishock J, Tortella FC, Kochanek PM, Shear DA. Simvastatin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26541177 DOI: 10.1089/Neu.2015.4130  1
2015 Kochanek PM, Bramlett HM, Dixon CE, Shear DA, Dietrich WD, Schmid K, Mondello S, Wang KK, Hayes RL, Povlishock J, Tortella St FC. Operation Brain Trauma Therapy: Approach to Modeling, Therapy Evaluation, Drug Selection, and Biomarker Assessments, for a Multi-Center Pre-Clinical Drug Screening Consortium for Acute Therapies in Severe Traumatic Brain Injury. Journal of Neurotrauma. PMID 26439468 DOI: 10.1089/Neu.2015.4113  1
2015 Fink EL, Kochanek PM. It Seems Like the Resuscitation Happened Ages Ago-Chronic Critical Illness in Children: Digging in for the Long Haul. Critical Care Medicine. 43: 2035-6. PMID 26274715 DOI: 10.1097/Ccm.0000000000001100  1
2015 Jackson TC, Manole MD, Kotermanski SE, Jackson EK, Clark RS, Kochanek PM. Cold stress protein RBM3 responds to temperature change in an ultra-sensitive manner in young neurons. Neuroscience. 305: 268-78. PMID 26265550 DOI: 10.1016/J.Neuroscience.2015.08.012  1
2015 Fidan E, Lewis J, Kline AE, Garman RH, Alexander H, Cheng JP, Bondi CO, Clark R, Dezfulian C, Kochanek PM, Kagan VE, Bay?r H. Repetitive mild traumatic brain injury in the developing brain: effects on long-term functional outcome and neuropathology. Journal of Neurotrauma. PMID 26214116 DOI: 10.1089/Neu.2015.3958  1
2015 Diamond ML, Ritter AC, Failla MD, Boles JA, Conley YP, Kochanek PM, Wagner AK. IL-1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study. Epilepsia. 56: 991-1001. PMID 26149793 DOI: 10.1111/epi.13100  1
2015 Kochanek PM, Bell MJ. Tackling the Challenges of Clinical Trials for Severe Traumatic Brain Injury in Children: Screening, Phenotyping, and Adapting. Critical Care Medicine. 43: 1544-6. PMID 26079237 DOI: 10.1097/Ccm.0000000000001041  1
2015 Au AK, Chen Y, Lina D, Smith CM, Manole MD, Baltagi SA, Chu CT, Aneja RK, Bay?r H, Kochanek PM, Clark RS. Ischemia-induced autophagy contributes to neurodegeneration in cerebellar Purkinje cells in the developing rat brain and in primary cortical neurons in vitro. Biochimica Et Biophysica Acta. PMID 26071643 DOI: 10.1016/J.Bbadis.2015.06.007  1
2015 Shaik JS, Poloyac SM, Kochanek PM, Alexander H, Tudorascu DL, Clark RS, Manole MD. 20-Hydroxyeicosatetraenoic Acid Inhibition by HET0016 Offers Neuroprotection, Decreases Edema, and Increases Cortical Cerebral Blood Flow in a Pediatric Asphyxial Cardiac Arrest Model in Rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26058691 DOI: 10.1038/Jcbfm.2015.117  1
2015 Diamond ML, Ritter AC, Jackson EK, Conley YP, Kochanek PM, Boison D, Wagner AK. Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development. Epilepsia. PMID 26040919 DOI: 10.1111/Epi.13044  1
2015 Uray T, Mayr FB, Fitzgibbon J, Rittenberger JC, Callaway CW, Drabek T, Fabio A, Angus DC, Kochanek PM, Dezfulian C. Socioeconomic factors associated with outcome after cardiac arrest in patients under the age of 65. Resuscitation. 93: 14-9. PMID 26003812 DOI: 10.1016/J.Resuscitation.2015.04.032  1
2015 Verrier JD, Kochanek PM, Jackson EK. Schwann Cells Metabolize Extracellular 2',3'-cAMP to 2'-AMP. The Journal of Pharmacology and Experimental Therapeutics. 354: 175-83. PMID 25998049 DOI: 10.1124/Jpet.115.225219  1
2015 Donnelly MK, Crago EA, Conley YP, Balzer JR, Ren D, Ducruet AF, Kochanek PM, Sherwood PR, Poloyac SM. 20-HETE is associated with unfavorable outcomes in subarachnoid hemorrhage patients. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 1515-22. PMID 25920956 DOI: 10.1038/Jcbfm.2015.75  1
2015 Willyerd FA, Empey PE, Philbrick A, Ikonomovic MD, Puccio AM, Kochanek PM, Okonkwo DO, Clark RS. Expression of ATP-Binding Cassette Transporters B1 and C1 after Severe Traumatic Brain Injury in Humans. Journal of Neurotrauma. PMID 25891836 DOI: 10.1089/Neu.2015.3879  1
2015 Newell E, Shellington DK, Simon DW, Bell MJ, Kochanek PM, Feldman K, Bayir H, Aneja RK, Carcillo JA, Clark RS. Cerebrospinal Fluid Markers of Macrophage and Lymphocyte Activation After Traumatic Brain Injury in Children. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 16: 549-57. PMID 25850867 DOI: 10.1097/Pcc.0000000000000400  1
2015 Jackson TC, Bayir H, Ikonomovic MD, Janesko-Feldman K, Mi Z, Gao T, Jackson EK, Kochanek PM. Detection of PHLPP1α/β in human and mouse brain by different anti-PHLPP1 antibodies. Scientific Reports. 5: 9377. PMID 25827478 DOI: 10.1038/Srep09377  1
2015 Kochanek PM, Jackson TC. It might be time to let cooler heads prevail after mild traumatic brain injury or concussion. Experimental Neurology. 267: 13-7. PMID 25732932 DOI: 10.1016/J.Expneurol.2015.02.019  1
2015 Kochanek PM, Jackson TC, Ferguson NM, Carlson SW, Simon DW, Brockman EC, Ji J, Bay?r H, Poloyac SM, Wagner AK, Kline AE, Empey PE, Clark RS, Jackson EK, Dixon CE. Emerging therapies in traumatic brain injury. Seminars in Neurology. 35: 83-100. PMID 25714870 DOI: 10.1055/S-0035-1544237  1
2015 Mtaweh H, Kochanek PM, Carcillo JA, Bell MJ, Fink EL. Patterns of multiorgan dysfunction after pediatric drowning. Resuscitation. 90: 91-6. PMID 25703785 DOI: 10.1016/J.Resuscitation.2015.02.005  1
2015 Chin KH, Bell MJ, Wisniewski SR, Balasubramani GK, Kochanek PM, Beers SR, Brown SD, Adelson PD. Effect of administration of neuromuscular blocking agents in children with severe traumatic brain injury on acute complication rates and outcomes: a secondary analysis from a randomized, controlled trial of therapeutic hypothermia. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 16: 352-8. PMID 25599147 DOI: 10.1097/Pcc.0000000000000344  1
2015 Jackson TC, Du L, Janesko-Feldman K, Vagni VA, Dezfulian C, Poloyac SM, Jackson EK, Clark RS, Kochanek PM. The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 655-66. PMID 25586139 DOI: 10.1038/Jcbfm.2014.242  1
2015 Kochanek PM, Dezfulian C. Asphyxial cardiac arrest from drowning: giving E-CPR the cold shoulder. Resuscitation. 88: A7-8. PMID 25576981 DOI: 10.1016/J.Resuscitation.2014.12.026  1
2015 Kumar RG, Diamond ML, Boles JA, Berger RP, Tisherman SA, Kochanek PM, Wagner AK. Acute CSF interleukin-6 trajectories after TBI: associations with neuroinflammation, polytrauma, and outcome. Brain, Behavior, and Immunity. 45: 253-62. PMID 25555531 DOI: 10.1016/J.Bbi.2014.12.021  1
2015 Berger RP, Fromkin J, Rubin P, Snyder J, Richichi R, Kochanek P. Serum D-dimer concentrations are increased after pediatric traumatic brain injury. The Journal of Pediatrics. 166: 383-8. PMID 25454315 DOI: 10.1016/J.Jpeds.2014.10.036  1
2015 Newell EA, Exo JL, Verrier JD, Jackson TC, Gillespie DG, Janesko-Feldman K, Kochanek PM, Jackson EK. 2',3'-cAMP, 3'-AMP, 2'-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors. Brain Research. 1594: 27-35. PMID 25451117 DOI: 10.1016/J.Brainres.2014.10.059  1
2015 Drabek T, Wilson CD, Janata A, Stezoski JP, Janesko-Feldman K, Garman RH, Tisherman SA, Kochanek PM. Unique brain region-dependent cytokine signatures after prolonged hypothermic cardiac arrest in rats. Therapeutic Hypothermia and Temperature Management. 5: 26-39. PMID 25423415 DOI: 10.1089/ther.2014.0013  1
2015 Ji J, Baart S, Vikulina AS, Clark RS, Anthonymuthu TS, Tyurin VA, Du L, St Croix CM, Tyurina YY, Lewis J, Skoda EM, Kline AE, Kochanek PM, Wipf P, Kagan VE, et al. Deciphering of mitochondrial cardiolipin oxidative signaling in cerebral ischemia-reperfusion. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 319-28. PMID 25407268 DOI: 10.1038/Jcbfm.2014.204  1
2015 Wiley CA, Bonneh-Barkay D, Dixon CE, Lesniak A, Wang G, Bissel SJ, Kochanek PM. Role for mammalian chitinase 3-like protein 1 in traumatic brain injury. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 35: 95-106. PMID 25377763 DOI: 10.1111/Neup.12158  1
2015 Santarsieri M, Kumar RG, Kochanek PM, Berga S, Wagner AK. Variable neuroendocrine-immune dysfunction in individuals with unfavorable outcome after severe traumatic brain injury. Brain, Behavior, and Immunity. 45: 15-27. PMID 25218898 DOI: 10.1016/J.Bbi.2014.09.003  1
2015 Wallisch J, Jha R, Vagni V, Feldman K, Dixon C, Farr G, Kochanek P. 23: Effect Of The Novel Aquaporin-4 Antagonist Aer-271 In Combined Tbi Plus Hemorrhagic Shock In Mice. Critical Care Medicine. 43: 6-7. DOI: 10.1097/01.Ccm.0000473851.20338.3B  1
2015 Fidan E, Foley L, New L, Kochanek P, Hitchens TK, Bayir H. 18: In Vivo Metabolic and Structural Imaging at 7t After Mild Traumatic Brain Injury in Immature Rats Critical Care Medicine. 43: 5. DOI: 10.1097/01.Ccm.0000473846.89843.A0  1
2015 Kim-Campbell N, Krehel N, Drabek T, Gladwin M, Callaway C, Dezfulian C, Bayir H, Kochanek P. 9: Renal Injury Associated With Free Hemoglobin In Rat Cardiopulmonary Bypass Is Attenuated By Nitrite. Critical Care Medicine. 43: 3. DOI: 10.1097/01.Ccm.0000473837.77933.31  1
2014 Kochanek PM, Kissoon N. PCCM 2014: Extracorporeal support and more. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 15: 797. PMID 25370052 DOI: 10.1097/Pcc.0000000000000258  1
2014 Drabek T, Kochanek PM. Improving outcomes from resuscitation: from hypertension and hemodilution to therapeutic hypothermia to H2. Circulation. 130: 2133-5. PMID 25366996 DOI: 10.1161/Circulationaha.114.013566  1
2014 Diamond ML, Boles JA, Ritter AC, Failla MD, Conley YP, Kochanek PM, Wagner AK. In response to comments on IL-1β associations with posttraumatic epilepsy development: a genetics and biomarker cohort study. Epilepsia. 55: 1313-4. PMID 25099304 DOI: 10.1111/Epi.12714  1
2014 Uray T, Kochanek PM. Finding a faster and safer way to "catch a cold" after cardiac arrest: we may be getting closer. Resuscitation. 85: 1131-3. PMID 24992871 DOI: 10.1016/J.Resuscitation.2014.06.021  1
2014 Jackson EK, Cheng D, Verrier JD, Janesko-Feldman K, Kochanek PM. Interactive roles of CD73 and tissue nonspecific alkaline phosphatase in the renal vascular metabolism of 5'-AMP. American Journal of Physiology. Renal Physiology. 307: F680-5. PMID 24990899 DOI: 10.1152/Ajprenal.00312.2014  1
2014 Gao W, Lu C, Kochanek PM, Berger RP. Serum amyloid A is increased in children with abusive head trauma: a gel-based proteomic analysis. Pediatric Research. 76: 280-6. PMID 24941216 DOI: 10.1038/Pr.2014.86  1
2014 Tress EE, Clark RS, Foley LM, Alexander H, Hickey RW, Drabek T, Kochanek PM, Manole MD. Blood brain barrier is impermeable to solutes and permeable to water after experimental pediatric cardiac arrest. Neuroscience Letters. 578: 17-21. PMID 24937271 DOI: 10.1016/J.Neulet.2014.06.020  1
2014 Tyurina YY, Poloyac SM, Tyurin VA, Kapralov AA, Jiang J, Anthonymuthu TS, Kapralova VI, Vikulina AS, Jung MY, Epperly MW, Mohammadyani D, Klein-Seetharaman J, Jackson TC, Kochanek PM, Pitt BR, et al. A mitochondrial pathway for biosynthesis of lipid mediators. Nature Chemistry. 6: 542-52. PMID 24848241 DOI: 10.1038/Nchem.1924  1
2014 Jackson EK, Gillespie DG, Mi Z, Cheng D, Bansal R, Janesko-Feldman K, Kochanek PM. Role of 2',3'-cyclic nucleotide 3'-phosphodiesterase in the renal 2',3'-cAMP-adenosine pathway. American Journal of Physiology. Renal Physiology. 307: F14-24. PMID 24808540 DOI: 10.1152/Ajprenal.00134.2014  1
2014 Shein SL, Shellington DK, Exo JL, Jackson TC, Wisniewski SR, Jackson EK, Vagni VA, Bay?r H, Clark RS, Dixon CE, Janesko-Feldman KL, Kochanek PM. Hemorrhagic shock shifts the serum cytokine profile from pro- to anti-inflammatory after experimental traumatic brain injury in mice. Journal of Neurotrauma. 31: 1386-95. PMID 24773520 DOI: 10.1089/Neu.2013.2985  1
2014 Diamond ML, Ritter AC, Failla MD, Boles JA, Conley YP, Kochanek PM, Wagner AK. IL-1β associations with posttraumatic epilepsy development: a genetics and biomarker cohort study. Epilepsia. 55: 1109-19. PMID 24754437 DOI: 10.1111/Epi.12628  1
2014 Drabek T, Foley LM, Janata A, Stezoski J, Hitchens TK, Manole MD, Kochanek PM. Global and regional differences in cerebral blood flow after asphyxial versus ventricular fibrillation cardiac arrest in rats using ASL-MRI. Resuscitation. 85: 964-71. PMID 24727136 DOI: 10.1016/J.Resuscitation.2014.03.314  1
2014 Bell MJ, Mtaweh H, Bayir H, Kochanek PM. Authors' response to letter to the editor, "Effect of a single dose of propofol and lack of dextrose administration in a child with mitochondrial disease--a case report". Journal of Child Neurology. 29: 1576-7. PMID 24682288 DOI: 10.1177/0883073813515301  1
2014 Walko TD, Bola RA, Hong JD, Au AK, Bell MJ, Kochanek PM, Clark RS, Aneja RK. Cerebrospinal fluid mitochondrial DNA: a novel DAMP in pediatric traumatic brain injury. Shock (Augusta, Ga.). 41: 499-503. PMID 24667615 DOI: 10.1097/Shk.0000000000000160  1
2014 Janata A, Magnet IA, Uray T, Stezoski JP, Janesko-Feldman K, Tisherman SA, Kochanek PM, Drabek T. Regional TNFα mapping in the brain reveals the striatum as a neuroinflammatory target after ventricular fibrillation cardiac arrest in rats. Resuscitation. 85: 694-701. PMID 24530249 DOI: 10.1016/J.Resuscitation.2014.01.033  1
2014 Drabek T, Janata A, Wilson CD, Stezoski J, Janesko-Feldman K, Tisherman SA, Foley LM, Verrier JD, Kochanek PM. Minocycline attenuates brain tissue levels of TNF-α produced by neurons after prolonged hypothermic cardiac arrest in rats. Resuscitation. 85: 284-91. PMID 24513126 DOI: 10.1016/J.Resuscitation.2013.10.015  1
2014 Kochanek PM, Callaway CW. Targeting therapeutic hypothermia in neonatal resuscitation and beyond: it is time to phenotype. Resuscitation. 85: 458-9. PMID 24462759 DOI: 10.1016/J.Resuscitation.2014.01.012  1
2014 Mtaweh H, Smith R, Kochanek PM, Wisniewski SR, Fabio A, Vavilala MS, Adelson PD, Toney NA, Bell MJ. Energy expenditure in children after severe traumatic brain injury. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 15: 242-9. PMID 24394999 DOI: 10.1097/Pcc.0000000000000041  1
2014 Alexander SA, Ren D, Gunn SR, Kochanek PM, Tate J, Ikonomovic M, Conley YP. Interleukin 6 and apolipoprotein E as predictors of acute brain dysfunction and survival in critical care patients. American Journal of Critical Care : An Official Publication, American Association of Critical-Care Nurses. 23: 49-57. PMID 24382617 DOI: 10.4037/Ajcc2014578  1
2014 Kochanek PM, Jackson TC. Will the next breakthrough for neuroprotection after cardiac arrest come out of thin air? Shock (Augusta, Ga.). 41: 85-6. PMID 24346648 DOI: 10.1097/Shk.0000000000000057  1
2014 Manole MD, Kochanek PM, Bay?r H, Alexander H, Dezfulian C, Fink EL, Bell MJ, Clark RS. Brain tissue oxygen monitoring identifies cortical hypoxia and thalamic hyperoxia after experimental cardiac arrest in rats. Pediatric Research. 75: 295-301. PMID 24226633 DOI: 10.1038/Pr.2013.220  1
2014 Fink EL, Berger RP, Clark RS, Watson RS, Angus DC, Richichi R, Panigrahy A, Callaway CW, Bell MJ, Kochanek PM. Serum biomarkers of brain injury to classify outcome after pediatric cardiac arrest*. Critical Care Medicine. 42: 664-74. PMID 24164954 DOI: 10.1097/01.Ccm.0000435668.53188.80  1
2014 Mtaweh H, Bay?r H, Kochanek PM, Bell MJ. Effect of a single dose of propofol and lack of dextrose administration in a child with mitochondrial disease: a case report. Journal of Child Neurology. 29: NP40-6. PMID 24026895 DOI: 10.1177/0883073813498640  1
2014 Diaz-Arrastia R, Kochanek PM, Bergold P, Kenney K, Marx CE, Grimes CJ, Loh LT, Adam LT, Oskvig D, Curley KC, Salzer W. Pharmacotherapy of traumatic brain injury: state of the science and the road forward: report of the Department of Defense Neurotrauma Pharmacology Workgroup. Journal of Neurotrauma. 31: 135-58. PMID 23968241 DOI: 10.1089/neu.2013.3019  1
2014 Anderson K, Liput S, Fink E, Kochanek P, Empey P, Poloyac S. 652: Uplc-Ms/Ms Method For Assessing Phenytoin And Levetiracetam Concentrations In Pediatric Ca Patients Critical Care Medicine. 42. DOI: 10.1097/01.Ccm.0000458149.28972.4C  1
2014 Hagos F, Ocque J, Nolin T, Poloyac S, Bayir H, Kochanek P, Clark R, Empey P. 627: Probenecid Increases N-Acetylcysteine Brain Levels Critical Care Medicine. 42. DOI: 10.1097/01.Ccm.0000458124.29933.D9  1
2014 Newmyer R, Kuch B, Fink E, Kochanek P, Orr R. 576: Outcome Is Associated With Type Of Neurologic Disease During Specialized Transport Of Children Critical Care Medicine. 42. DOI: 10.1097/01.Ccm.0000458073.17365.3F  1
2014 Simon D, Aneja R, Lewis J, Alexander H, Bell M, Bayir H, Kochanek P, Clark R. 527: Minocycline Delays Recovery In A Model Of Pediatric Traumatic Brain Injury Critical Care Medicine. 42. DOI: 10.1097/01.Ccm.0000458024.61282.2C  1
2014 Slocum B, Smith K, Clark R, Richichi R, Angus D, Kochanek P, Watson R, Fink E. 366: Cost Analysis Of The Pangea Study Critical Care Medicine. 42. DOI: 10.1097/01.Ccm.0000457863.58329.5A  1
2014 Slocum B, Smith K, Clark R, Richichi R, Angus D, Kochanek P, Watson R, Fink E. 365: Characteristics Of Long Stay Patients In Pediatric Intensive Care Units In The United States Critical Care Medicine. 42. DOI: 10.1097/01.Ccm.0000457862.58329.13  1
2014 Mendelson J, Bayir H, Kochanek P, Fink E. 255: Serum Cytochrome C Is Associated With Outcome And Cardiac Dysfunction After Pediatric Cardiac Arrest Critical Care Medicine. 42. DOI: 10.1097/01.Ccm.0000457752.77355.94  1
2014 Anetakis K, Gedela S, Kochanek P, Sogawa Y, Fink E. 107: Combining Eeg And Serum Brain Biomarkers To Classify Mortality After Pediatric Cardiac Arrest Critical Care Medicine. 42. DOI: 10.1097/01.Ccm.0000457604.74401.60  1
2014 Uray T, Drabek T, Stezoski JP, Misse A, Janesko-Feldman K, Tisherman SA, Kochanek PM, Dezfulian C. Comparison of injury phenotype between ventricular fibrillation and asphyxial cardiac arrest in a rat model Resuscitation. 85. DOI: 10.1016/J.Resuscitation.2014.03.232  1
2013 Kochanek PM, Bell MJ. Making an IMPACT in traumatic brain injury research. The Lancet. Neurology. 12: 1132-3. PMID 24139679 DOI: 10.1016/S1474-4422(13)70245-X  1
2013 Kochanek PM, Kissoon N. Progress amidst some anticipated growing pains for PCCM. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 14: 739-40. PMID 24096687 DOI: 10.1097/01.Pcc.0000434436.80537.58  1
2013 Jackson EK, Cheng D, Mi Z, Verrier JD, Janesko-Feldman K, Kochanek PM. Role of CD73 in Renal Sympathetic Neurotransmission in the Mouse Kidney. Physiological Reports. 1. PMID 24066228 DOI: 10.1002/Phy2.57  1
2013 Jackson TC, Verrier JD, Drabek T, Janesko-Feldman K, Gillespie DG, Uray T, Dezfulian C, Clark RS, Bayir H, Jackson EK, Kochanek PM. Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes. The Journal of Pharmacology and Experimental Therapeutics. 347: 516-28. PMID 24023368 DOI: 10.1124/Jpet.113.206888  1
2013 Verrier JD, Jackson TC, Gillespie DG, Janesko-Feldman K, Bansal R, Goebbels S, Nave KA, Kochanek PM, Jackson EK. Role of CNPase in the oligodendrocytic extracellular 2',3'-cAMP-adenosine pathway. Glia. 61: 1595-606. PMID 23922219 DOI: 10.1002/Glia.22523  1
2013 Empey PE, de Mendizabal NV, Bell MJ, Bies RR, Anderson KB, Kochanek PM, Adelson PD, Poloyac SM. Therapeutic hypothermia decreases phenytoin elimination in children with traumatic brain injury. Critical Care Medicine. 41: 2379-87. PMID 23896831 DOI: 10.1097/Ccm.0B013E318292316C  1
2013 Cousar JL, Conley YP, Willyerd FA, Sarnaik AA, Puccio AM, Empey PE, Kochanek PM, Bell MJ, Okonkwo DO, Clark RS. Influence of ATP-binding cassette polymorphisms on neurological outcome after traumatic brain injury. Neurocritical Care. 19: 192-8. PMID 23896815 DOI: 10.1007/S12028-013-9881-7  1
2013 Kochanek PM. A new roadmap for mechanical circulatory support in children. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 14: 447. PMID 23867426 DOI: 10.1097/Pcc.0B013E318290825A  0.01
2013 Bell MJ, Adelson PD, Hutchison JS, Kochanek PM, Tasker RC, Vavilala MS, Beers SR, Fabio A, Kelsey SF, Wisniewski SR. Differences in medical therapy goals for children with severe traumatic brain injury-an international study. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 14: 811-8. PMID 23863819 DOI: 10.1097/Pcc.0B013E3182975E2F  1
2013 Brockman EC, Bay?r H, Blasiole B, Shein SL, Fink EL, Dixon C, Clark RS, Vagni VA, Ma L, Hsia CJ, Tisherman SA, Kochanek PM. Polynitroxylated-pegylated hemoglobin attenuates fluid requirements and brain edema in combined traumatic brain injury plus hemorrhagic shock in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1457-64. PMID 23801241 DOI: 10.1038/Jcbfm.2013.104  1
2013 Janata A, Drabek T, Magnet IA, Stezoski JP, Janesko-Feldman K, Popp E, Garman RH, Tisherman SA, Kochanek PM. Extracorporeal versus conventional cardiopulmonary resuscitation after ventricular fibrillation cardiac arrest in rats: a feasibility trial. Critical Care Medicine. 41: e211-22. PMID 23666097 DOI: 10.1097/Ccm.0B013E318287F51E  1
2013 Kochanek PM, Berger RP, Fink EL, Au AK, Bay?r H, Bell MJ, Dixon CE, Clark RS. The potential for bio-mediators and biomarkers in pediatric traumatic brain injury and neurocritical care. Frontiers in Neurology. 4: 40. PMID 23637695 DOI: 10.3389/Fneur.2013.00040  1
2013 Bell MJ, Kochanek PM. Pediatric traumatic brain injury in 2012: the year with new guidelines and common data elements. Critical Care Clinics. 29: 223-38. PMID 23537673 DOI: 10.1016/J.Ccc.2012.11.004  1
2013 Kochanek PM, Dixon CE, Shellington DK, Shin SS, Bay?r H, Jackson EK, Kagan VE, Yan HQ, Swauger PV, Parks SA, Ritzel DV, Bauman R, Clark RS, Garman RH, Bandak F, et al. Screening of biochemical and molecular mechanisms of secondary injury and repair in the brain after experimental blast-induced traumatic brain injury in rats. Journal of Neurotrauma. 30: 920-37. PMID 23496248 DOI: 10.1089/Neu.2013.2862  1
2013 Abrahamson EE, Foley LM, Dekosky ST, Hitchens TK, Ho C, Kochanek PM, Ikonomovic MD. Cerebral blood flow changes after brain injury in human amyloid-beta knock-in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 826-33. PMID 23443172 DOI: 10.1038/Jcbfm.2013.24  1
2013 Thampatty BP, Klamerus MM, Oberly PJ, Feldman KL, Bell MJ, Tyler-Kabara EC, Adelson PD, Clark RS, Kochanek PM, Poloyac SM. Hypothermia decreases cerebrospinal fluid asymmetric dimethylarginine levels in children with traumatic brain injury. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 14: 403-12. PMID 23439461 DOI: 10.1097/Pcc.0B013E31827212C0  1
2013 Jackson TC, Verrier JD, Kochanek PM. Anthraquinone-2-sulfonic acid (AQ2S) is a novel neurotherapeutic agent. Cell Death & Disease. 4: e451. PMID 23303125 DOI: 10.1038/Cddis.2012.187  1
2013 Blasiole B, Bayr H, Vagni VA, Janesko-Feldman K, Cheikhi A, Wisniewski SR, Long JB, Atkins J, Kagan V, Kochanek PM. Effect of hyperoxia on resuscitation of experimental combined traumatic brain injury and hemorrhagic shock in mice. Anesthesiology. 118: 649-63. PMID 23299361 DOI: 10.1097/Aln.0B013E318280A42D  1
2013 Adelson PD, Fellows-Mayle W, Kochanek PM, Dixon CE. Morris water maze function and histologic characterization of two age-at-injury experimental models of controlled cortical impact in the immature rat. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. 29: 43-53. PMID 23089934 DOI: 10.1007/S00381-012-1932-4  1
2013 Foley LM, Iqbal O'Meara AM, Wisniewski SR, Hitchens TK, Melick JA, Ho C, Jenkins LW, Kochanek PM. MRI assessment of cerebral blood flow after experimental traumatic brain injury combined with hemorrhagic shock in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 129-36. PMID 23072750 DOI: 10.1038/Jcbfm.2012.145  1
2013 Fink EL, Panigrahy A, Clark RS, Fitz CR, Landsittel D, Kochanek PM, Zuccoli G. Regional brain injury on conventional and diffusion weighted MRI is associated with outcome after pediatric cardiac arrest. Neurocritical Care. 19: 31-40. PMID 22535278 DOI: 10.1007/S12028-012-9706-0  1
2013 Fink E, Tasker R, Beca J, Bell M, Clark R, Hutchison J, Vavilala M, Watson R, Weissfeld L, Kochanek P, Angus D, Investigators P. Prevalence of acute critical neurological disease in children: a global epidemiological assessment (PANGEA) Critical Care. 17: 346. DOI: 10.1186/Cc12284  1
2013 Mtaweh H, Toney N, Kochanek P, Bell M. 464: Nutrition Titrated To Energy Expenditure In Children With Traumatic Brain Injury-A Feasibility Study Critical Care Medicine. 41. DOI: 10.1097/01.Ccm.0000439608.71143.59  1
2013 Ferguson NM, Shein S, Kochanek P, Clark R, Tyler-Kabara E, Bell M. 448: Defining The Onset Of Intracranial Hypertension After Severe Traumatic Brain Injury In Children Critical Care Medicine. 41. DOI: 10.1097/01.Ccm.0000439592.87352.A4  1
2013 Au A, Aneja R, Bell M, Feldman K, Kochanek P, Clark R. 13: Autophagy Biomarkers Beclin 1 And P62 Are Detectable In Cerebrospinal Fluid After Tbi In Children Critical Care Medicine. 41. DOI: 10.1097/01.Ccm.0000439198.39093.83  1
2013 Simon D, Aneja R, Lewis J, Bayir H, Bell M, Kochanek P, Clark R. 10: Hmgb1 Translocation And Microglial Activation After Pediatric Tbi Attenuated By Minocycline Critical Care Medicine. 41. DOI: 10.1097/01.Ccm.0000439195.54340.48  1
2013 Dezfulian C, Misse A, Stezoski JP, Kochanek PM, Bayir H, Clark RS. P65: Nitrite after cardiac arrest has antioxidant effects reducing reperfusion cerebral hyperemia and subsequent caspase activation Nitric Oxide. 31. DOI: 10.1016/J.Niox.2013.02.067  1
2013 Uray T, Drabek T, Stezoski JP, Janesko-Feldman K, Tisherman SA, Kochanek PM, Dezfulian C. P35: Nitrite as a novel resuscitation adjunct after ventricular fibrillation cardiac arrest in rats: A preliminary report Nitric Oxide. 31. DOI: 10.1016/J.Niox.2013.02.037  1
2013 Kenny EM, Misse A, Kochanek PM, Bayir H, Clark RS, Dezfulian C. PSS287 - Nitrite Protects after Global Cerebral Ischemia by Reducing Mitochondrial ROS and Improving Mitochondrial Function Free Radical Biology and Medicine. 65. DOI: 10.1016/J.Freeradbiomed.2013.10.711  1
2012 Kochanek PM, Fink EL, Bell MJ. Politics and hypothermia-what might they have in common? Editorial comment on silasi and colbourne, 2011. Therapeutic Hypothermia and Temperature Management. 2: 11-3. PMID 24717133 DOI: 10.1089/Ther.2012.1504  1
2012 Kochanek PM, Erlinge D, Polderman KH, Windsor J. Developing cooling strategies targeting the heart in adults and children. Therapeutic Hypothermia and Temperature Management. 2: 157-61. PMID 24716488 DOI: 10.1089/ther.2012.1518  0.01
2012 Shein SL, Reynolds TQ, Gedela S, Kochanek PM, Bell MJ. Therapeutic hypothermia for refractory status epilepticus in a child with malignant migrating partial seizures of infancy and SCN1A mutation: a case report. Therapeutic Hypothermia and Temperature Management. 2: 144-9. PMID 23667778 DOI: 10.1089/Ther.2012.0013  1
2012 Drabek T, Kochanek PM. Therapeutic Hypothermia on Its 10th Anniversary: Is it Time to Turn the Thermostat Down? Circulation. 126: 2803-5. PMID 23230314 DOI: 10.1161/Circulationaha.112.153619  1
2012 Kochanek PM, Kissoon N. Pediatric Critical Care Medicine reaches another milestone. Foreword. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 13: 623-4. PMID 23128587 DOI: 10.1097/Pcc.0B013E31826B773D  1
2012 Shein SL, Bell MJ, Su E, Kochanek PM, Exo J. Intracranial monitoring and continuous data collection. Critical Care Medicine. 40: 3115-6; author reply. PMID 23080469 DOI: 10.1097/Ccm.0B013E31826563C8  1
2012 Alam HB, Pusateri AE, Kindzelski A, Egan D, Hoots K, Andrews MT, Rhee P, Tisherman S, Mann K, Vostal J, Kochanek PM, Scalea T, Deal V, Sheppard F, Sopko G, et al. Hypothermia and hemostasis in severe trauma: A new crossroads workshop report. The Journal of Trauma and Acute Care Surgery. 73: 809-17. PMID 23026915 DOI: 10.1097/Ta.0B013E318265D1B8  1
2012 Kochanek PM, Bayır H. Optimizing oxygenation and ventilation after cardiac arrest in "little adults". Resuscitation. 83: 1425-6. PMID 22986065 DOI: 10.1016/J.Resuscitation.2012.09.004  1
2012 Stippler M, Ortiz V, Adelson PD, Chang YF, Tyler-Kabara EC, Wisniewski SR, Fink EL, Kochanek PM, Brown SD, Bell MJ. Brain tissue oxygen monitoring after severe traumatic brain injury in children: relationship to outcome and association with other clinical parameters. Journal of Neurosurgery. Pediatrics. 10: 383-91. PMID 22978637 DOI: 10.3171/2012.8.Peds12165  1
2012 Topjian AA, Berg RA, Bierens JJ, Branche CM, Clark RS, Friberg H, Hoedemaekers CW, Holzer M, Katz LM, Knape JT, Kochanek PM, Nadkarni V, van der Hoeven JG, Warner DS. Brain resuscitation in the drowning victim. Neurocritical Care. 17: 441-67. PMID 22956050 DOI: 10.1007/S12028-012-9747-4  1
2012 Ji J, Kline AE, Amoscato A, Samhan-Arias AK, Sparvero LJ, Tyurin VA, Tyurina YY, Fink B, Manole MD, Puccio AM, Okonkwo DO, Cheng JP, Alexander H, Clark RS, Kochanek PM, et al. Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury. Nature Neuroscience. 15: 1407-13. PMID 22922784 DOI: 10.1038/Nn.3195  1
2012 Su E, Bell MJ, Kochanek PM, Wisniewski SR, Bayir H, Clark RS, Adelson PD, Tyler-Kabara EC, Janesko-Feldman KL, Berger RP. Increased CSF concentrations of myelin basic protein after TBI in infants and children: absence of significant effect of therapeutic hypothermia. Neurocritical Care. 17: 401-7. PMID 22890910 DOI: 10.1007/S12028-012-9767-0  1
2012 Jackson EK, Cheng D, Mi Z, Verrier JD, Janesko-Feldman K, Kochanek PM. Role of A1 receptors in renal sympathetic neurotransmission in the mouse kidney. American Journal of Physiology. Renal Physiology. 303: F1000-5. PMID 22874760 DOI: 10.1152/Ajprenal.00363.2012  1
2012 Hemerka JN, Wu X, Dixon CE, Garman RH, Exo JL, Shellington DK, Blasiole B, Vagni VA, Janesko-Feldman K, Xu M, Wisniewski SR, Bay?r H, Jenkins LW, Clark RS, Tisherman SA, ... Kochanek PM, et al. Severe brief pressure-controlled hemorrhagic shock after traumatic brain injury exacerbates functional deficits and long-term neuropathological damage in mice. Journal of Neurotrauma. 29: 2192-208. PMID 22738159 DOI: 10.1089/Neu.2011.2303  1
2012 Sparvero LJ, Amoscato AA, Dixon CE, Long JB, Kochanek PM, Pitt BR, Bayir H, Kagan VE. Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations. Chemistry and Physics of Lipids. 165: 545-62. PMID 22692104 DOI: 10.1016/J.Chemphyslip.2012.06.001  1
2012 Shein SL, Bell MJ, Kochanek PM, Tyler-Kabara EC, Wisniewski SR, Feldman K, Makoroff K, Scribano PV, Berger RP. Risk factors for mortality in children with abusive head trauma. The Journal of Pediatrics. 161: 716-722.e1. PMID 22578583 DOI: 10.1016/J.Jpeds.2012.03.046  1
2012 Au AK, Aneja RK, Bell MJ, Bayir H, Feldman K, Adelson PD, Fink EL, Kochanek PM, Clark RS. Cerebrospinal fluid levels of high-mobility group box 1 and cytochrome C predict outcome after pediatric traumatic brain injury. Journal of Neurotrauma. 29: 2013-21. PMID 22540160 DOI: 10.1089/Neu.2011.2171  1
2012 Shoykhet M, Simons DJ, Alexander H, Hosler C, Kochanek PM, Clark RS. Thalamocortical dysfunction and thalamic injury after asphyxial cardiac arrest in developing rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4972-81. PMID 22492052 DOI: 10.1523/Jneurosci.5597-11.2012  1
2012 Verrier JD, Jackson TC, Bansal R, Kochanek PM, Puccio AM, Okonkwo DO, Jackson EK. The brain in vivo expresses the 2',3'-cAMP-adenosine pathway. Journal of Neurochemistry. 122: 115-25. PMID 22360621 DOI: 10.1111/J.1471-4159.2012.07705.X  1
2012 Kochanek PM, Carney N, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghajar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tasker RC, et al. Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents--second edition. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 13: S1-82. PMID 22217782 DOI: 10.1097/Pcc.0B013E31823F435C  1
2012 Manole MD, Kochanek PM, Foley LM, Hitchens TK, Bay?r H, Alexander H, Garman R, Ma L, Hsia CJ, Ho C, Clark RS. Polynitroxyl albumin and albumin therapy after pediatric asphyxial cardiac arrest: effects on cerebral blood flow and neurologic outcome. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 560-9. PMID 22126915 DOI: 10.1038/Jcbfm.2011.165  1
2012 Salonia R, Bell MJ, Kochanek PM, Berger RP. The utility of near infrared spectroscopy in detecting intracranial hemorrhage in children. Journal of Neurotrauma. 29: 1047-53. PMID 22098538 DOI: 10.1089/Neu.2011.1890  1
2012 Empey PE, Miller TM, Philbrick AH, Melick JA, Kochanek PM, Poloyac SM. Mild hypothermia decreases fentanyl and midazolam steady-state clearance in a rat model of cardiac arrest. Critical Care Medicine. 40: 1221-8. PMID 22067624 DOI: 10.1097/Ccm.0B013E31823779F9  1
2012 Drabek T, Janata A, Jackson EK, End B, Stezoski J, Vagni VA, Janesko-Feldman K, Wilson CD, van Rooijen N, Tisherman SA, Kochanek PM. Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats. Resuscitation. 83: 517-26. PMID 21970817 DOI: 10.1016/J.Resuscitation.2011.09.016  1
2012 Ji J, Tyurina YY, Tang M, Feng W, Stolz DB, Clark RS, Meaney DF, Kochanek PM, Kagan VE, Bay?r H. Mitochondrial injury after mechanical stretch of cortical neurons in vitro: biomarkers of apoptosis and selective peroxidation of anionic phospholipids. Journal of Neurotrauma. 29: 776-88. PMID 21895519 DOI: 10.1089/Neu.2010.1602  1
2012 Mills PH, Hitchens TK, Foley LM, Link T, Ye Q, Weiss CR, Thompson JD, Gilson WD, Arepally A, Melick JA, Kochanek PM, Ho C, Bulte JW, Ahrens ET. Automated detection and characterization of SPIO-labeled cells and capsules using magnetic field perturbations. Magnetic Resonance in Medicine. 67: 278-89. PMID 21656554 DOI: 10.1002/Mrm.22998  1
2012 Smith RL, Lin JC, Adelson PD, Kochanek PM, Fink EL, Wisniewski SR, Bayir H, Tyler-Kabara EC, Clark RS, Brown SD, Bell MJ. Relationship between hyperglycemia and outcome in children with severe traumatic brain injury. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 13: 85-91. PMID 21499170 DOI: 10.1097/Pcc.0B013E3182192C30  1
2012 Fink EL, Kochanek PM, Clark RS, Bell MJ. Fever control and application of hypothermia using intravenous cold saline. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 13: 80-4. PMID 21037507 DOI: 10.1097/Pcc.0B013E3181Fe27C7  1
2012 Brilli R, Kochanek PM. The SQUIRE has arrived Pediatric Critical Care Medicine. 13: 499-500. DOI: 10.1097/Pcc.0B013E31825E26B0  0.01
2012 Kochanek PM, Carney N, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghajar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tasker RC, et al. Comments about the revised guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents Pediatric Critical Care Medicine. 13: 496-497. DOI: 10.1097/Pcc.0B013E318259Ee85  1
2012 Kochanek PM, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghahar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tong KA, Tasker RC, et al. Chapter 16. Glucose and nutrition Pediatric Critical Care Medicine. 13. DOI: 10.1097/Pcc.0B013E31823F681D  1
2012 Kochanek PM, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghahar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tong KA, Tasker RC, et al. Chapter 15. Analgesics, sedatives, and neuromuscular blockade Pediatric Critical Care Medicine. 13. DOI: 10.1097/Pcc.0B013E31823F67Fc  1
2012 Kochanek PM, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghahar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tong KA, Tasker RC, et al. Chapter 14. Corticosteroids Pediatric Critical Care Medicine. 13. DOI: 10.1097/Pcc.0B013E31823F67E3  1
2012 Kochanek PM, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghahar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tong KA, Tasker RC, et al. Chapter 12. Decompressive craniectomy for the treatment of intracranial hypertension Pediatric Critical Care Medicine. 13. DOI: 10.1097/Pcc.0B013E31823F6765  1
2012 Kochanek PM, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghahar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tong KA, Tasker RC, et al. Chapter 11. Barbiturates Pediatric Critical Care Medicine. 13. DOI: 10.1097/Pcc.0B013E31823F672E  1
2012 Kochanek PM, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghahar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tong KA, Tasker RC, et al. Chapter 10. Cerebrospinal fluid drainage Pediatric Critical Care Medicine. 13. DOI: 10.1097/Pcc.0B013E31823F6696  1
2012 Kochanek PM, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghahar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tong KA, Tasker RC, et al. Chapter 9. Temperature control Pediatric Critical Care Medicine. 13. DOI: 10.1097/Pcc.0B013E31823F664B  1
2012 Kochanek PM, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghahar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tong KA, Tasker RC, et al. Chapter 8. Hyperosmolar therapy Pediatric Critical Care Medicine. 13. DOI: 10.1097/Pcc.0B013E31823F6621  1
2012 Kochanek PM, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghahar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tong KA, Tasker RC, et al. Chapter 7. Neuroimaging Pediatric Critical Care Medicine. 13. DOI: 10.1097/Pcc.0B013E31823F65E2  1
2012 Kochanek PM, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghahar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tong KA, Tasker RC, et al. Chapter 6. Advanced neuromonitoring Pediatric Critical Care Medicine. 13. DOI: 10.1097/Pcc.0B013E31823F659A  1
2012 Kochanek PM, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghahar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tong KA, Tasker RC, et al. Chapter 5. Cerebral perfusion pressure thresholds Pediatric Critical Care Medicine. 13. DOI: 10.1097/Pcc.0B013E31823F4450  1
2012 Kochanek PM, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghahar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tong KA, Tasker RC, et al. Chapter 3. Indications for intracranial pressure monitoring Pediatric Critical Care Medicine. 13. DOI: 10.1097/Pcc.0B013E31823F440C  1
2012 Kochanek PM, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghahar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tong KA, Tasker RC, et al. Chapter 2. Methods Pediatric Critical Care Medicine. 13. DOI: 10.1097/Pcc.0B013E31823F43Df  1
2012 Mtaweh H, Kochanek P, Bell M, Fink E. 853: Cerebral And Extracerebral Manifestations In Pediatric Drowning Critical Care Medicine. 40: 1-328. DOI: 10.1097/01.Ccm.0000425068.19321.B4  1
2012 Brockman E, Dixon C, Bayir H, Blasiole B, Clark R, Vagni V, Ma L, Hsia C, Kochanek P. 531: Polynitroxylated Pegylated Hemoglobin Attenuates Fluid Requirements And Brain Edema In Combined Traumatic Brain Injury Plus Hemorrhagic Shock In Mice Critical Care Medicine. 40: 1-328. DOI: 10.1097/01.Ccm.0000424749.78837.0B  1
2012 Ferguson NM, Shein S, Kochanek P, Clark R, Tyler-Kabara E, Bell M. 382: Understanding The Burden Of Intracranial Hypertension And Cerebral Hypoperfusion In Pediatric Traumatic Brain Injury (Tbi) – A Preliminary Analysis Critical Care Medicine. 40: 1-328. DOI: 10.1097/01.Ccm.0000424600.70801.3A  1
2012 Ferguson NM, Shein S, Kochanek P, Clark R, Tyler-Kabara E, Bell M. 375: Objective Quantification Of Intracranial Hypertension - A Novel Approach Critical Care Medicine. 40: 1-328. DOI: 10.1097/01.Ccm.0000424593.94564.8A  1
2012 Shein S, Feldman K, Vagni V, Xu M, Brockman E, Bayir H, Clark R, Kochanek P. 198: Delayed Hyperthermia Exacerbates Experimental Traumatic Brain Injury Critical Care Medicine. 40: 1-328. DOI: 10.1097/01.Ccm.0000424418.75053.57  1
2011 Kochanek PM. Mass critical care for children: implications for adult critical care. Critical Care Medicine. 39: 2783. PMID 22094518 DOI: 10.1097/Ccm.0B013E318236E99A  0.01
2011 Manole MD, Tehranian-DePasquale R, Du L, Bayir H, Kochanek PM, Clark RS. Unmasking sex-based disparity in neuronal metabolism. Current Pharmaceutical Design. 17: 3854-60. PMID 21933143 DOI: 10.2174/138161211798357737  1
2011 Manole MD, Kochanek PM, Clark RS. "Lost in translation?" Noninvasive cerebral monitoring after cardiac arrest. Critical Care Medicine. 39: 2379-80. PMID 21926503 DOI: 10.1097/Ccm.0B013E31822B3863  1
2011 Zhou J, Empey PE, Bies RR, Kochanek PM, Poloyac SM. Cardiac arrest and therapeutic hypothermia decrease isoform-specific cytochrome P450 drug metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 2209-18. PMID 21868471 DOI: 10.1124/Dmd.111.040642  1
2011 Belikova NA, Glumac AL, Kapralova V, Cheikhi A, Tyurina YY, Vagni VA, Kochanek PM, Kagan VE, Bayir H. A high-throughput screening assay of ascorbate in brain samples. Journal of Neuroscience Methods. 201: 185-90. PMID 21855575 DOI: 10.1016/J.Jneumeth.2011.08.001  1
2011 Kochanek PM, Bramlett H, Dietrich WD, Dixon CE, Hayes RL, Povlishock J, Tortella FC, Wang KK. A novel multicenter preclinical drug screening and biomarker consortium for experimental traumatic brain injury: operation brain trauma therapy. The Journal of Trauma. 71: S15-24. PMID 21795873 DOI: 10.1097/Ta.0B013E31822117Fe  1
2011 Verrier JD, Exo JL, Jackson TC, Ren J, Gillespie DG, Dubey RK, Kochanek PM, Jackson EK. Expression of the 2',3'-cAMP-adenosine pathway in astrocytes and microglia. Journal of Neurochemistry. 118: 979-87. PMID 21777245 DOI: 10.1111/J.1471-4159.2011.07392.X  1
2011 Adelson PD, Srinivas R, Chang Y, Bell M, Kochanek PM. Cerebrovascular response in children following severe traumatic brain injury. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. 27: 1465-76. PMID 21559825 DOI: 10.1007/S00381-011-1476-Z  1
2011 Garman RH, Jenkins LW, Switzer RC, Bauman RA, Tong LC, Swauger PV, Parks SA, Ritzel DV, Dixon CE, Clark RS, Bayir H, Kagan V, Jackson EK, Kochanek PM. Blast exposure in rats with body shielding is characterized primarily by diffuse axonal injury. Journal of Neurotrauma. 28: 947-59. PMID 21449683 DOI: 10.1089/Neu.2010.1540  1
2011 Wagner AK, Amin KB, Niyonkuru C, Postal BA, McCullough EH, Ozawa H, Dixon CE, Bayir H, Clark RS, Kochanek PM, Fabio A. CSF Bcl-2 and cytochrome C temporal profiles in outcome prediction for adults with severe TBI. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1886-96. PMID 21448217 DOI: 10.1038/Jcbfm.2011.31  1
2011 Kochanek PM, Kissoon N. Pediatric Critical Care Medicine: re-tooling to accommodate growth and success while preserving excellence. Pediatric Critical Care Medicine. 12: 1. PMID 21209568 DOI: 10.1097/Pcc.0B013E318206853B  1
2011 Shellington DK, Du L, Wu X, Exo J, Vagni V, Ma L, Janesko-Feldman K, Clark RS, Bayir H, Dixon CE, Jenkins LW, Hsia CJ, Kochanek PM. Polynitroxylated pegylated hemoglobin: a novel neuroprotective hemoglobin for acute volume-limited fluid resuscitation after combined traumatic brain injury and hemorrhagic hypotension in mice. Critical Care Medicine. 39: 494-505. PMID 21169820 DOI: 10.1097/Ccm.0B013E318206B1Fa  1
2011 Walson KH, Tang M, Glumac A, Alexander H, Manole MD, Ma L, Hsia CJ, Clark RS, Kochanek PM, Kagan VE, Bayr H. Normoxic versus hyperoxic resuscitation in pediatric asphyxial cardiac arrest: effects on oxidative stress. Critical Care Medicine. 39: 335-43. PMID 21057313 DOI: 10.1097/Ccm.0B013E3181Ffda0E  1
2011 Smith CM, Chen Y, Sullivan ML, Kochanek PM, Clark RS. Autophagy in acute brain injury: feast, famine, or folly? Neurobiology of Disease. 43: 52-9. PMID 20883784 DOI: 10.1016/J.Nbd.2010.09.014  1
2011 Smith CM, Adelson PD, Chang YF, Brown SD, Kochanek PM, Clark RS, Bayir H, Hinchberger J, Bell MJ. Brain-systemic temperature gradient is temperature-dependent in children with severe traumatic brain injury. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 12: 449-54. PMID 20711083 DOI: 10.1097/Pcc.0B013E3181F390Dd  1
2011 Exo J, Kochanek PM, Adelson PD, Greene S, Clark RS, Bayir H, Wisniewski SR, Bell MJ. Intracranial pressure-monitoring systems in children with traumatic brain injury: combining therapeutic and diagnostic tools. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 12: 560-5. PMID 20625341 DOI: 10.1097/Pcc.0B013E3181E8B3Ee  1
2011 Drabek T, Kochanek PM, Stezoski J, Wu X, Bayir H, Morhard RC, Stezoski SW, Tisherman SA. Intravenous hydrogen sulfide does not induce hypothermia or improve survival from hemorrhagic shock in pigs. Shock (Augusta, Ga.). 35: 67-73. PMID 20523266 DOI: 10.1097/Shk.0B013E3181E86F49  1
2011 Kochanek PM, Kissoon N. The impact of Pediatric Critical Care Medicine in 2011 Pediatric Critical Care Medicine. 12: 493. DOI: 10.1097/Pcc.0B013E31822E9Ad6  1
2010 Kochanek PM, Bell MJ, Bay?r H. Quo vadis 2010? - carpe diem: challenges and opportunities in pediatric traumatic brain injury. Developmental Neuroscience. 32: 335-42. PMID 21252553 DOI: 10.1159/000323016  1
2010 Su E, Bell MJ, Wisniewski SR, Adelson PD, Janesko-Feldman KL, Salonia R, Clark RS, Kochanek PM, Kagan VE, Bay?r H. α-Synuclein levels are elevated in cerebrospinal fluid following traumatic brain injury in infants and children: the effect of therapeutic hypothermia. Developmental Neuroscience. 32: 385-95. PMID 21124000 DOI: 10.1159/000321342  1
2010 Sparvero LJ, Amoscato AA, Kochanek PM, Pitt BR, Kagan VE, Bayir H. Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury. Journal of Neurochemistry. 115: 1322-36. PMID 20950335 DOI: 10.1111/J.1471-4159.2010.07055.X  1
2010 Tress EE, Kochanek PM, Saladino RA, Manole MD. Cardiac arrest in children. Journal of Emergencies, Trauma, and Shock. 3: 267-272. PMID 20930971 DOI: 10.4103/0974-2700.66528  1
2010 Mehta A, Kochanek PM, Tyler-Kabara E, Adelson PD, Wisniewski SR, Berger RP, Sidoni MD, Bell RL, Clark RS, Bell MJ. Relationship of intracranial pressure and cerebral perfusion pressure with outcome in young children after severe traumatic brain injury. Developmental Neuroscience. 32: 413-9. PMID 20847542 DOI: 10.1159/000316804  1
2010 Berger RP, Bazaco MC, Wagner AK, Kochanek PM, Fabio A. Trajectory analysis of serum biomarker concentrations facilitates outcome prediction after pediatric traumatic and hypoxemic brain injury. Developmental Neuroscience. 32: 396-405. PMID 20847541 DOI: 10.1159/000316803  1
2010 Salonia R, Empey PE, Poloyac SM, Wisniewski SR, Klamerus M, Ozawa H, Wagner AK, Ruppel R, Bell MJ, Feldman K, Adelson PD, Clark RS, Kochanek PM. Endothelin-1 is increased in cerebrospinal fluid and associated with unfavorable outcomes in children after severe traumatic brain injury. Journal of Neurotrauma. 27: 1819-25. PMID 20684675 DOI: 10.1089/Neu.2010.1402  1
2010 Stoyanovsky DA, Kapralov A, Huang Z, Maeda A, Osipov A, Hsia CJ, Ma L, Kochanek PM, Bayr H, Kagan VE. Unusual peroxidase activity of polynitroxylated pegylated hemoglobin: Elimination of H(2)O(2) coupled with intramolecular oxidation of nitroxides. Biochemical and Biophysical Research Communications. 399: 139-43. PMID 20643098 DOI: 10.1016/J.Bbrc.2010.07.030  1
2010 Wagner AK, Miller MA, Scanlon J, Ren D, Kochanek PM, Conley YP. Adenosine A1 receptor gene variants associated with post-traumatic seizures after severe TBI. Epilepsy Research. 90: 259-72. PMID 20609566 DOI: 10.1016/J.Eplepsyres.2010.06.001  1
2010 Janata A, Weihs W, Schratter A, Bayegan K, Holzer M, Frossard M, Sipos W, Springler G, Schmidt P, Sterz F, Losert UM, Laggner AN, Kochanek PM, Behringer W. Cold aortic flush and chest compressions enable good neurologic outcome after 15 mins of ventricular fibrillation in cardiac arrest in pigs. Critical Care Medicine. 38: 1637-1643. PMID 20543671 DOI: 10.1097/Ccm.0B013E3181E78B9A  1
2010 Kochanek PM, Bayir H. Titrating oxygen during and after cardiopulmonary resuscitation. Jama. 303: 2190-1. PMID 20516423 DOI: 10.1001/Jama.2010.715  1
2010 Hostler D, Zhou J, Tortorici MA, Bies RR, Rittenberger JC, Empey PE, Kochanek PM, Callaway CW, Poloyac SM. Mild hypothermia alters midazolam pharmacokinetics in normal healthy volunteers. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 781-8. PMID 20164112 DOI: 10.1124/Dmd.109.031377  1
2010 Fink EL, Kochanek PM, Clark RS, Bell MJ. How I cool children in neurocritical care. Neurocritical Care. 12: 414-20. PMID 20146026 DOI: 10.1007/S12028-010-9334-5  1
2010 Haselkorn ML, Shellington DK, Jackson EK, Vagni VA, Janesko-Feldman K, Dubey RK, Gillespie DG, Cheng D, Bell MJ, Jenkins LW, Homanics GE, Schnermann J, Kochanek PM. Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice. Journal of Neurotrauma. 27: 901-10. PMID 20121416 DOI: 10.1089/Neu.2009.1075  1
2010 Baltagi SA, Shoykhet M, Felmet K, Kochanek PM, Bell MJ. Neurological sequelae of 2009 influenza A (H1N1) in children: a case series observed during a pandemic. Pediatric Critical Care Medicine. 11: 179-184. PMID 20081552 DOI: 10.1097/Pcc.0B013E3181Cf4652  1
2010 Tyurin VA, Tyurina YY, Ritov VB, Lysytsya A, Amoscato AA, Kochanek PM, Hamilton R, Dekosky ST, Greenberger JS, Bayir H, Kagan VE. Oxidative lipidomics of apoptosis: quantitative assessment of phospholipid hydroperoxides in cells and tissues. Methods in Molecular Biology (Clifton, N.J.). 610: 353-74. PMID 20013189 DOI: 10.1007/978-1-60327-029-8_21  1
2010 Fink EL, Clark RS, Kochanek PM, Bell MJ, Watson RS. A tertiary care center's experience with therapeutic hypothermia after pediatric cardiac arrest. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 11: 66-74. PMID 19935440 DOI: 10.1097/Pcc.0B013E3181C58237  1
2010 Sarnaik AA, Conley YP, Okonkwo DO, Barr TL, Fink EL, Szabo C, Kochanek PM, Clark RS. Influence of PARP-1 polymorphisms in patients after traumatic brain injury. Journal of Neurotrauma. 27: 465-71. PMID 19925161 DOI: 10.1089/Neu.2009.1171  1
2010 Au AK, Bayir H, Kochanek PM, Clark RS. Evaluation of autophagy using mouse models of brain injury. Biochimica Et Biophysica Acta. 1802: 918-23. PMID 19879944 DOI: 10.1016/J.Bbadis.2009.10.010  1
2010 Tang M, Alexander H, Clark RS, Kochanek PM, Kagan VE, Bayir H. Minocycline reduces neuronal death and attenuates microglial response after pediatric asphyxial cardiac arrest. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 119-29. PMID 19756023 DOI: 10.1038/Jcbfm.2009.194  1
2010 Kochanek PM, Bell MJ, Bayır H, Wu TC, Wilde EA, Bigler ED, Li X, Merkley TL, Yallampalli R, McCauley SR, Schnelle KP, Vasquez AC, Chu Z, Hanten G, Hunter JV, et al. Subject Index Vol. 32, 2010 Developmental Neuroscience. 32: 523-524. DOI: 10.1159/000324018  1
2010 Janata A, Drabek T, Stezoski JP, Magnet IAM, Popp E, Garman RH, Janesko-Feldman K, Macfarlane K, Culver S, Dixon CE, Tisherman SA, Kochanek PM. Exploratory study of emergency cardiopulmonary bypass for resuscitation from ventricular fibrillation cardiac arrest in rats Resuscitation. 81. DOI: 10.1016/J.Resuscitation.2010.09.091  1
2010 Drabek T, Kochanek PM. 62 – Is Hypothermia Useful in Managing Critically Ill Patients? Which Ones? Under What Conditions? Evidence-Based Practice. 437-444. DOI: 10.1016/B978-1-4160-5476-4.00062-6  1
2009 Manole MD, Kochanek PM, Fink EL, Clark RS. Postcardiac arrest syndrome: focus on the brain. Current Opinion in Pediatrics. 21: 745-50. PMID 19726989 DOI: 10.1097/Mop.0B013E328331E873  1
2009 Exo JL, Shellington DK, Bayir H, Vagni VA, Janesco-Feldman K, Ma L, Hsia CJ, Clark RS, Jenkins LW, Dixon CE, Kochanek PM. Resuscitation of traumatic brain injury and hemorrhagic shock with polynitroxylated albumin, hextend, hypertonic saline, and lactated Ringer's: Effects on acute hemodynamics, survival, and neuronal death in mice. Journal of Neurotrauma. 26: 2403-8. PMID 19691424 DOI: 10.1089/Neu.2009.0980  1
2009 Drabek T, Tisherman SA, Beuke L, Stezoski J, Janesko-Feldman K, Lahoud-Rahme M, Kochanek PM. Deep hypothermia attenuates microglial proliferation independent of neuronal death after prolonged cardiac arrest in rats. Anesthesia & Analgesia. 109: 914-923. PMID 19690267 DOI: 10.1213/Ane.0B013E3181B0511E  1
2009 de Toledo JS, Adelson PD, Watson RS, Gaines B, Brown SD, Kochanek PM, Wisniewski SR, Fink E, Bayir H, Clark RS, Bell MJ. Relationship between increases in pancreatic enzymes and cerebral events in children after traumatic brain injury. Neurocritical Care. 11: 322-9. PMID 19669945 DOI: 10.1007/S12028-009-9265-1  1
2009 Foley LM, Hitchens TK, Ho C, Janesko-Feldman KL, Melick JA, Bayir H, Kochanek PM. Magnetic resonance imaging assessment of macrophage accumulation in mouse brain after experimental traumatic brain injury. Journal of Neurotrauma. 26: 1509-19. PMID 19663686 DOI: 10.1089/Neu.2008.0747  1
2009 Kochanek PM, Tasker RC. Pediatric neurointensive care: 2008 update for the Rogers' Textbook of Pediatric Intensive Care. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 10: 517-23. PMID 19584637 DOI: 10.1097/Pcc.0B013E3181Ab88Cd  1
2009 Kochanek PM, Bauman RA, Long JB, Dixon CR, Jenkins LW. A critical problem begging for new insight and new therapies. Journal of Neurotrauma. 26: 813-4. PMID 19514110 DOI: 10.1089/Neu.2008.0893  1
2009 Puccio AM, Hoffman LA, Bayir H, Zullo TG, Fischer M, Darby J, Alexander S, Dixon CE, Okonkwo DO, Kochanek PM. Effect of short periods of normobaric hyperoxia on local brain tissue oxygenation and cerebrospinal fluid oxidative stress markers in severe traumatic brain injury. Journal of Neurotrauma. 26: 1241-9. PMID 19505175 DOI: 10.1089/Neu.2008.0624  1
2009 Kochanek PM. Bakken Lecture: the brain, the heart, and therapeutic hypothermia. Cleveland Clinic Journal of Medicine. 76. PMID 19376990 DOI: 10.3949/Ccjm.76.S2.02  0.01
2009 Tyurin VA, Tyurina YY, Jung MY, Tungekar MA, Wasserloos KJ, Bayir H, Greenberger JS, Kochanek PM, Shvedova AA, Pitt B, Kagan VE. Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 877: 2863-72. PMID 19328050 DOI: 10.1016/J.Jchromb.2009.03.007  1
2009 Dietrich WD, Bullock MR, Kochanek PM. Hypothermic therapies targeting brain and spinal cord injury. Introduction. Journal of Neurotrauma. 26: 297-8. PMID 19292693 DOI: 10.1089/Neu.2009.9958  1
2009 Kagan VE, Bayir HA, Belikova NA, Kapralov O, Tyurina YY, Tyurin VA, Jiang J, Stoyanovsky DA, Wipf P, Kochanek PM, Greenberger JS, Pitt B, Shvedova AA, Borisenko G. Cytochrome c/cardiolipin relations in mitochondria: a kiss of death. Free Radical Biology & Medicine. 46: 1439-53. PMID 19285551 DOI: 10.1016/J.Freeradbiomed.2009.03.004  1
2009 Kochanek PM, Fink EL, Bell MJ, Bayir H, Clark RS. Therapeutic hypothermia: applications in pediatric cardiac arrest. Journal of Neurotrauma. 26: 421-7. PMID 19271968 DOI: 10.1089/Neu.2008.0587  1
2009 Kochanek PM, Drabek T, Tisherman SA. Therapeutic Hypothermia: The Safar Vision Journal of Neurotrauma. 26: 417-420. PMID 19271966 DOI: 10.1089/Neu.2008.0612  1
2009 Lahoud-Rahme MS, Stezoski J, Kochanek PM, Melick J, Tisherman SA, Drabek T. Blood-brain barrier integrity in a rat model of emergency preservation and resuscitation Resuscitation. 80: 484-488. PMID 19203824 DOI: 10.1016/J.Resuscitation.2009.01.007  1
2009 Tortorici MA, Mu Y, Kochanek PM, Xie W, Poloyac SM. Moderate hypothermia prevents cardiac arrest-mediated suppression of drug metabolism and induction of interleukin-6 in rats. Critical Care Medicine. 37: 263-9. PMID 19050605 DOI: 10.1097/Ccm.0B013E3181931Ed3  1
2009 Du L, Hickey RW, Bayir H, Watkins SC, Tyurin VA, Guo F, Kochanek PM, Jenkins LW, Ren J, Gibson G, Chu CT, Kagan VE, Clark RS. Starving neurons show sex difference in autophagy. The Journal of Biological Chemistry. 284: 2383-96. PMID 19036730 DOI: 10.1074/Jbc.M804396200  1
2009 Manole MD, Foley LM, Hitchens TK, Kochanek PM, Hickey RW, Bayir H, Alexander H, Ho C, Clark RS. Magnetic resonance imaging assessment of regional cerebral blood flow after asphyxial cardiac arrest in immature rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 197-205. PMID 18827831 DOI: 10.1038/Jcbfm.2008.112  1
2009 Berger RP, Ta'asan S, Rand A, Lokshin A, Kochanek P. Multiplex assessment of serum biomarker concentrations in well-appearing children with inflicted traumatic brain injury. Pediatric Research. 65: 97-102. PMID 18787505 DOI: 10.1203/Pdr.0B013E31818C7E27  1
2009 Dennis AM, Haselkorn ML, Vagni VA, Garman RH, Janesko-Feldman K, Bayir H, Clark RS, Jenkins LW, Dixon CE, Kochanek PM. Hemorrhagic shock after experimental traumatic brain injury in mice: effect on neuronal death. Journal of Neurotrauma. 26: 889-99. PMID 18781889 DOI: 10.1089/Neu.2008.0512  1
2009 Kochanek PM, Kissoon N, Ewers J. PCCM makes an impact Pediatric Critical Care Medicine. 10: 543. DOI: 10.1097/Pcc.0B013E3181B7D5F3  1
2009 Kochanek PM. Reviewer Thank You Pediatric Critical Care Medicine. 10: 128-129. DOI: 10.1097/Pcc.0B013E31819382Ad  0.01
2009 Kochanek PM, Bauman RA, Long J, Dixon CE, Jenkins LW. Blast-induced traumatic brain injury and polytrauma--a critical problem begging for new insight and new therapies Journal of Neurotrauma. 110306202455053. DOI: 10.1089/Neu.2009-0893  1
2009 Drabek T, Tisherman SA, Garman RH, Kochanek PM. Reply to: Delta-opioid receptor ligands in shock treatment Resuscitation. 80: 1331-1332. DOI: 10.1016/J.Resuscitation.2009.08.008  1
2008 Bell MJ, Kochanek PM. Traumatic brain injury in children: recent advances in management. Indian Journal of Pediatrics. 75: 1159-1165. PMID 19132318 DOI: 10.1007/S12098-008-0240-1  1
2008 Tyurin VA, Tyurina YY, Feng W, Mnuskin A, Jiang J, Tang M, Zhang X, Zhao Q, Kochanek PM, Clark RS, Bayir H, Kagan VE. Mass-spectrometric characterization of phospholipids and their primary peroxidation products in rat cortical neurons during staurosporine-induced apoptosis. Journal of Neurochemistry. 107: 1614-33. PMID 19014376 DOI: 10.1111/J.1471-4159.2008.05728.X  1
2008 Manole MD, Hickey RW, Clark RS, Kochanek PM. Current and future therapies of pediatric cardiopulmonary arrest. Indian Journal of Pediatrics. 75: 609-14. PMID 18759090 DOI: 10.1007/S12098-008-0117-3  1
2008 Ahmad M, Rose ME, Vagni V, Griffith RP, Dixon CE, Kochanek PM, Hickey RW, Graham SH. Genetic disruption of cyclooxygenase-2 does not improve histological or behavioral outcome after traumatic brain injury in mice. Journal of Neuroscience Research. 86: 3605-12. PMID 18711748 DOI: 10.1002/Jnr.21809  1
2008 Tyurin VA, Tyurina YY, Kochanek PM, Hamilton R, DeKosky ST, Greenberger JS, Bayir H, Kagan VE. Oxidative lipidomics of programmed cell death. Methods in Enzymology. 442: 375-93. PMID 18662580 DOI: 10.1016/S0076-6879(08)01419-5  1
2008 Han F, Drabek T, Stezoski J, Janesko-Feldman K, Stezoski SW, Clark RS, Bayir H, Tisherman SA, Kochanek PM. Protein nitration and poly-ADP-ribosylation in brain after rapid exsanguination cardiac arrest in a rat model of emergency preservation and resuscitation. Resuscitation. 79: 301-10. PMID 18640761 DOI: 10.1016/J.Resuscitation.2008.06.004  1
2008 Tehranian R, Rose ME, Vagni V, Pickrell AM, Griffith RP, Liu H, Clark RS, Dixon CE, Kochanek PM, Graham SH. Disruption of Bax protein prevents neuronal cell death but produces cognitive impairment in mice following traumatic brain injury. Journal of Neurotrauma. 25: 755-67. PMID 18627254 DOI: 10.1089/Neu.2007.0441  1
2008 Hartman M, Watson RS, Linde-Zwirble W, Clermont G, Lave J, Weissfeld L, Kochanek P, Angus D. Pediatric traumatic brain injury is inconsistently regionalized in the United States Pediatrics. 122: e172-e180. PMID 18595962 DOI: 10.1542/Peds.2007-3399  1
2008 Fink EL, Lai Y, Zhang X, Janesko-Feldman K, Adelson PD, Szabó C, Berger RP, Sarnaik AA, Kochanek PM, Clark RS. Quantification of poly(ADP-ribose)-modified proteins in cerebrospinal fluid from infants and children after traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1523-9. PMID 18506195 DOI: 10.1038/Jcbfm.2008.52  1
2008 Drabek T, Kochanek PM. In quest of the optimal cooling device: isn't faster "too fast"? Critical Care Medicine. 36: 1018-1020. PMID 18431312 DOI: 10.1097/Ccm.0B013E318165Fd07  1
2008 Kochanek PM, Berger RP, Bayir H, Wagner AK, Jenkins LW, Clark RS. Biomarkers of primary and evolving damage in traumatic and ischemic brain injury: diagnosis, prognosis, probing mechanisms, and therapeutic decision making. Current Opinion in Critical Care. 14: 135-41. PMID 18388674 DOI: 10.1097/Mcc.0B013E3282F57564  1
2008 Foley LM, Hitchens TK, Melick JA, Bayir H, Ho C, Kochanek PM. Effect of inducible nitric oxide synthase on cerebral blood flow after experimental traumatic brain injury in mice. Journal of Neurotrauma. 25: 299-310. PMID 18373480 DOI: 10.1089/Neu.2007.0471  1
2008 Drabek T, Han F, Garman RH, Stezoski J, Tisherman SA, Stezoski SW, Morhard RC, Kochanek PM. Assessment of the delta opioid agonist DADLE in a rat model of lethal hemorrhage treated by emergency preservation and resuscitation. Resuscitation. 77: 220-8. PMID 18207625 DOI: 10.1016/J.Resuscitation.2007.11.020  1
2008 Lai Y, Chen Y, Watkins SC, Nathaniel PD, Guo F, Kochanek PM, Jenkins LW, Szabó C, Clark RS. Identification of poly-ADP-ribosylated mitochondrial proteins after traumatic brain injury. Journal of Neurochemistry. 104: 1700-11. PMID 17996029 DOI: 10.1111/J.1471-4159.2007.05114.X  1
2008 Clark RS, Bayir H, Chu CT, Alber SM, Kochanek PM, Watkins SC. Autophagy is increased in mice after traumatic brain injury and is detectable in human brain after trauma and critical illness. Autophagy. 4: 88-90. PMID 17957135 DOI: 10.4161/Auto.5173  1
2008 Lai Y, Hickey RW, Chen Y, Bayir H, Sullivan ML, Chu CT, Kochanek PM, Dixon CE, Jenkins LW, Graham SH, Watkins SC, Clark RS. Autophagy is increased after traumatic brain injury in mice and is partially inhibited by the antioxidant gamma-glutamylcysteinyl ethyl ester. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 540-50. PMID 17786151 DOI: 10.1038/Sj.Jcbfm.9600551  1
2008 Sachse KT, Jackson EK, Wisniewski SR, Gillespie DG, Puccio AM, Clark RS, Dixon CE, Kochanek PM. Increases in cerebrospinal fluid caffeine concentration are associated with favorable outcome after severe traumatic brain injury in humans. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 395-401. PMID 17684518 DOI: 10.1038/Sj.Jcbfm.9600539  1
2008 Wu X, Drabek T, Tisherman SA, Henchir J, Stezoski SW, Culver S, Stezoski J, Jackson EK, Garman R, Kochanek PM. Emergency preservation and resuscitation with profound hypothermia, oxygen, and glucose allows reliable neurological recovery after 3 h of cardiac arrest from rapid exsanguination in dogs. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 302-11. PMID 17622254 DOI: 10.1038/Sj.Jcbfm.9600524  1
2008 Kochanek PM, Kissoon N. PCCM moves to online-only publication of case reports Pediatric Critical Care Medicine. 9: 1. DOI: 10.1097/01.Pcc.0000299392.39076.Cd  1
2007 Buttram SD, Wisniewski SR, Jackson EK, Adelson PD, Feldman K, Bayir H, Berger RP, Clark RS, Kochanek PM. Multiplex assessment of cytokine and chemokine levels in cerebrospinal fluid following severe pediatric traumatic brain injury: effects of moderate hypothermia. Journal of Neurotrauma. 24: 1707-17. PMID 18001201 DOI: 10.1089/Neu.2007.0349  1
2007 Janata A, Bayegan K, Weihs WMMV, Schratter A, Holzer M, Frossard M, Sipos WD, Springler GMMV, Schmidt PD, Sterz F, Losert UM, Laggner AN, Kochanek PM, Behringer W. Emergency preservation and resuscitation improve survival after 15 minutes of normovolemic cardiac arrest in pigs. Critical Care Medicine. 35: 2785-2791. PMID 17901836 DOI: 10.1097/01.Ccm.0000288103.86029.66  1
2007 Tortorici MA, Kochanek PM, Poloyac SM. Effects of hypothermia on drug disposition, metabolism, and response: A focus of hypothermia-mediated alterations on the cytochrome P450 enzyme system. Critical Care Medicine. 35: 2196-204. PMID 17855837 DOI: 10.1097/01.Ccm.0000281517.97507.6E  1
2007 Bayir H, Tyurin VA, Tyurina YY, Viner R, Ritov V, Amoscato AA, Zhao Q, Zhang XJ, Janesko-Feldman KL, Alexander H, Basova LV, Clark RS, Kochanek PM, Kagan VE. Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis. Annals of Neurology. 62: 154-69. PMID 17685468 DOI: 10.1002/Ana.21168  1
2007 Drabek T, Fisk JA, Dixon CE, Garman RH, Stezoski J, Wisnewski SR, Wu X, Tisherman SA, Kochanek PM. Prolonged deep hypothermic circulatory arrest in rats can be achieved without cognitive deficits. Life Sciences. 81: 543-52. PMID 17658556 DOI: 10.1016/J.Lfs.2007.06.015  1
2007 Drabek T, Stezoski J, Garman RH, Han F, Henchir J, Tisherman SA, Stezoski SW, Kochanek PM. Exsanguination cardiac arrest in rats treated by 60 min, but not 75 min, emergency preservation and delayed resuscitation is associated with intact outcome. Resuscitation. 75: 114-23. PMID 17481798 DOI: 10.1016/J.Resuscitation.2007.03.012  1
2007 Fink EL, Callaway CW, Tisherman SA, Kochanek PM. Winning the cold war: inroads into implementation of mild hypothermia after cardiac arrest in adults from the European Resuscitation Council Hypothermia After Cardiac Arrest Registry Study Group. Critical Care Medicine. 35: 1199-202. PMID 17413789 DOI: 10.1097/01.Ccm.0000259495.93720.D7  1
2007 Bayir H, Kagan VE, Clark RS, Janesko-Feldman K, Rafikov R, Huang Z, Zhang X, Vagni V, Billiar TR, Kochanek PM. Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury. Journal of Neurochemistry. 101: 168-81. PMID 17394464 DOI: 10.1111/J.1471-4159.2006.04353.X  1
2007 Shore PM, Berger RP, Varma S, Janesko KL, Wisniewski SR, Clark RS, Adelson PD, Thomas NJ, Lai YC, Bayir H, Kochanek PM. Cerebrospinal fluid biomarkers versus glasgow coma scale and glasgow outcome scale in pediatric traumatic brain injury: the role of young age and inflicted injury. Journal of Neurotrauma. 24: 75-86. PMID 17263671 DOI: 10.1089/Neu.2006.0062  1
2007 Gao WM, Chadha MS, Berger RP, Omenn GS, Allen DL, Pisano M, Adelson PD, Clark RS, Jenkins LW, Kochanek PM. A gel-based proteomic comparison of human cerebrospinal fluid between inflicted and non-inflicted pediatric traumatic brain injury. Journal of Neurotrauma. 24: 43-53. PMID 17263669 DOI: 10.1089/Neu.2006.0061  1
2007 Drabek T, Stezoski J, Garman RH, Wu X, Tisherman SA, Stezoski SW, Fisk JA, Jenkins L, Kochanek PM. Emergency preservation and delayed resuscitation allows normal recovery after exsanguination cardiac arrest in rats: a feasibility trial. Critical Care Medicine. 35: 532-7. PMID 17205010 DOI: 10.1097/01.Ccm.0000253398.61666.0D  1
2007 Clark RS, Nathaniel PD, Zhang X, Dixon CE, Alber SM, Watkins SC, Melick JA, Kochanek PM, Graham SH. boc-Aspartyl(OMe)-fluoromethylketone attenuates mitochondrial release of cytochrome c and delays brain tissue loss after traumatic brain injury in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 316-26. PMID 16736044 DOI: 10.1038/Sj.Jcbfm.9600338  1
2007 Fink EL, Callaway CW, Tisherman SA, Kochanek PM. Hypothermia in traumatic brain injury Critical Care Medicine. 35: 1999-2000. DOI: 10.1097/01.Ccm.0000277067.67995.Ad  1
2007 Kochanek PM, Berger RP, Margulies SS, Jenkins LW. Inflicted childhood neurotrauma: New insight into the detection, pathobiology, prevention, and treatment of our youngest patients with traumatic brain injury Journal of Neurotrauma. 24: 1-4. DOI: 10.1089/Neu.2006.0209  1
2006 Zhang X, Alber S, Watkins SC, Kochanek PM, Marion DW, Graham SH, Clark RS. Proteolysis consistent with activation of caspase-7 after severe traumatic brain injury in humans. Journal of Neurotrauma. 23: 1583-90. PMID 17115905 DOI: 10.1089/Neu.2006.23.1583  1
2006 Berger RP, Kochanek PM. Urinary S100B concentrations are increased after brain injury in children: A preliminary study. Pediatric Critical Care Medicine. 7: 557-561. PMID 17006387 DOI: 10.1097/01.Pcc.0000244426.37793.23  1
2006 Bayir H, Kochanek PM, Kagan VE. Oxidative stress in immature brain after traumatic brain injury. Developmental Neuroscience. 28: 420-31. PMID 16943665 DOI: 10.1159/000094168  1
2006 Cousar JL, Lai Y, Marco CD, Bayir H, Adelson PD, Janesko-Feldman KL, Kochanek PM, Clark RS. Heme oxygenase 1 in cerebrospinal fluid from infants and children after severe traumatic brain injury. Developmental Neuroscience. 28: 342-7. PMID 16943657 DOI: 10.1159/000094160  1
2006 Lai Y, Stange C, Wisniewski SR, Adelson PD, Janesko-Feldman KL, Brown DS, Kochanek PM, Clark RS. Mitochondrial heat shock protein 60 is increased in cerebrospinal fluid following pediatric traumatic brain injury. Developmental Neuroscience. 28: 336-41. PMID 16943656 DOI: 10.1159/000094159  1
2006 Berger RP, Adelson PD, Richichi R, Kochanek PM. Serum biomarkers after traumatic and hypoxemic brain injuries: insight into the biochemical response of the pediatric brain to inflicted brain injury. Developmental Neuroscience. 28: 327-335. PMID 16943655 DOI: 10.1159/000094158  1
2006 Kochanek PM. Pediatric traumatic brain injury: quo vadis? Developmental Neuroscience. 28: 244-255. PMID 16943648 DOI: 10.1159/000094151  0.01
2006 Tehranian R, Rose ME, Vagni V, Griffith RP, Wu S, Maits S, Zhang X, Clark RS, Dixon CE, Kochanek PM, Bernard O, Graham SH. Transgenic mice that overexpress the anti-apoptotic Bcl-2 protein have improved histological outcome but unchanged behavioral outcome after traumatic brain injury. Brain Research. 1101: 126-35. PMID 16782076 DOI: 10.1016/J.Brainres.2006.05.049  1
2006 Nozari A, Safar P, Stezoski SW, Wu X, Kostelnik S, Radovsky A, Tisherman S, Kochanek PM. Critical time window for intra-arrest cooling with cold saline flush in a dog model of cardiopulmonary resuscitation. Circulation. 113: 2690-6. PMID 16769925 DOI: 10.1161/Circulationaha.106.613349  1
2006 Bayir H, Fadeel B, Palladino MJ, Witasp E, Kurnikov IV, Tyurina YY, Tyurin VA, Amoscato AA, Jiang J, Kochanek PM, DeKosky ST, Greenberger JS, Shvedova AA, Kagan VE. Apoptotic interactions of cytochrome c: redox flirting with anionic phospholipids within and outside of mitochondria. Biochimica Et Biophysica Acta. 1757: 648-59. PMID 16740248 DOI: 10.1016/J.Bbabio.2006.03.002  1
2006 Tyurina YY, Kapralov AA, Jiang J, Borisenko GG, Potapovich AI, Sorokin A, Kochanek PM, Graham SH, Schor NF, Kagan VE. Oxidation and cytotoxicity of 6-OHDA are mediated by reactive intermediates of COX-2 overexpressed in PC12 cells. Brain Research. 1093: 71-82. PMID 16712820 DOI: 10.1016/J.Brainres.2005.10.105  1
2006 Shore PM, Hand LL, Roy L, Trivedi P, Kochanek PM, Adelson PD. Reliability and validity of the Pediatric Intensity Level of Therapy (PILOT) scale: a measure of the use of intracranial pressure-directed therapies. Critical Care Medicine. 34: 1981-7. PMID 16691131 DOI: 10.1097/01.Ccm.0000220765.22184.Ed  1
2006 Wu X, Drabek T, Kochanek PM, Henchir J, Stezoski SW, Stezoski J, Cochran K, Garman R, Tisherman SA. Induction of profound hypothermia for emergency preservation and resuscitation allows intact survival after cardiac arrest resulting from prolonged lethal hemorrhage and trauma in dogs. Circulation. 113: 1974-82. PMID 16618818 DOI: 10.1161/Circulationaha.105.587204  1
2006 Poloyac SM, Zhang Y, Bies RR, Kochanek PM, Graham SH. Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 1551-61. PMID 16570075 DOI: 10.1038/Sj.Jcbfm.9600309  1
2006 Tortorici MA, Kochanek PM, Bies RR, Poloyac SM. Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model. Critical Care Medicine. 34: 785-91. PMID 16521272 DOI: 10.1097/01.Ccm.0000201899.52739.4F  1
2006 Statler KD, Alexander H, Vagni V, Holubkov R, Dixon CE, Clark RS, Jenkins L, Kochanek PM. Isoflurane exerts neuroprotective actions at or near the time of severe traumatic brain injury. Brain Research. 1076: 216-24. PMID 16473332 DOI: 10.1016/J.Brainres.2005.12.106  1
2006 Berger RP, Dulani T, Adelson PD, Leventhal JM, Richichi R, Kochanek PM. Identification of Inflicted Traumatic Brain Injury in Well-Appearing Infants Using Serum and Cerebrospinal Markers: A Possible Screening Tool Pediatrics. 117: 325-332. PMID 16452350 DOI: 10.1542/Peds.2005-0711  1
2006 Statler KD, Alexander H, Vagni V, Dixon CE, Clark RS, Jenkins L, Kochanek PM. Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats. Journal of Neurotrauma. 23: 97-108. PMID 16430376 DOI: 10.1089/Neu.2006.23.97  1
2006 Gao WM, Chadha MS, Kline AE, Clark RS, Kochanek PM, Dixon CE, Jenkins LW. Immunohistochemical analysis of histone H3 acetylation and methylation--evidence for altered epigenetic signaling following traumatic brain injury in immature rats. Brain Research. 1070: 31-4. PMID 16406269 DOI: 10.1016/J.Brainres.2005.11.038  1
2006 Kochanek PM, Clark RS, Statler KD, Jenkins LW. Physiological assessment and control in studies evaluating central nervous system injury: should size matter? Anesthesia and Analgesia. 102: 72-4. PMID 16368806 DOI: 10.1213/01.Ane.0000181101.71587.8A  1
2006 Zhang X, Chen Y, Ikonomovic MD, Nathaniel PD, Kochanek PM, Marion DW, DeKosky ST, Jenkins LW, Clark RS. Increased phosphorylation of protein kinase B and related substrates after traumatic brain injury in humans and rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 915-26. PMID 16234845 DOI: 10.1038/Sj.Jcbfm.9600238  1
2006 Kochanek PM, Vagni VA, Janesko KL, Washington CB, Crumrine PK, Garman RH, Jenkins LW, Clark RS, Homanics GE, Dixon CE, Schnermann J, Jackson EK. Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 565-75. PMID 16121125 DOI: 10.1038/Sj.Jcbfm.9600218  1
2006 Kochanek PM, Kissoon N. A special thanks to our friends and colleagues in Japan Pediatric Critical Care Medicine. 7: 199. DOI: 10.1097/01.Pcc.0000216678.75927.Da  1
2006 Kochanek PM. A new section in Pediatric Critical Care Medicine for our smallest patients Pediatric Critical Care Medicine. 7: 1. DOI: 10.1097/01.Pcc.0000194005.88263.0D  0.01
2006 Drabek T, Stezoski J, Han F, Tisherman SA, Kochanek PM. Effect Of A Delta-Opioid Agonist In A Rat Model Of Lethal Hemorrhage Treated By Emergency Preservation And Resuscitation.: 409 Critical Care Medicine. 34. DOI: 10.1097/00003246-200612002-00390  1
2006 Haselkorn ML, Dennis AM, Vagni V, Janesko-Feldman K, Clark RS, Jenkins LW, Dixon CE, Kochanek PM. Effect Of Hemorrhagic Shock On Neuronal Death After Experimental Traumatic Brain Injury In Mice.: 65 Critical Care Medicine. 34. DOI: 10.1097/00003246-200612002-00065  1
2006 Walson KH, Carcillo J, Aneja R, Clark RS, Kochanek P, Bayir H, Glumac A, Kagan V, Vlasova I, Kapralov O. Peroxidase Activity Of Hemoproteins Released Into Plasma As Sources Of Oxidative Stress In Sepsis: A Preliminary Report.: 60 Critical Care Medicine. 34. DOI: 10.1097/00003246-200612002-00060  1
2006 Kochanek PM, Melick JA, Foley LM, Hitchens TK, Ho C. Magnetic Resonance Imaging Assessment Of Macrophage Accumulation In Mouse Brain After Experimental Traumatic Brain Injury: A Preliminary Report.: 24 Critical Care Medicine. 34. DOI: 10.1097/00003246-200612002-00024  1
2006 Smith CM, Chen Y, Marco CD, Alexander HA, Jenkins LW, Kochanek PM, Clark RS. Gender- And Cell Compartment-Dependent Polyadp-Ribosylation After Traumatic Brain Injury In Juvenile Rats.: 18 Critical Care Medicine. 34. DOI: 10.1097/00003246-200612002-00018  1
2006 Dennis AM, Melick JA, Jenkins LW, Clark RS, Kochanek PM, Foley LM, Hitchens TK, Ho C. Effect Of Hemorrhagic Shock On Cerebral Blood Flow In Experimental Traumatic Brain Injury: Magnetic Resonance Imaging Assessment.: 17 Critical Care Medicine. 34. DOI: 10.1097/00003246-200612002-00017  1
2005 Wu X, Kochanek PM, Cochran K, Nozari A, Henchir J, Stezoski SW, Wagner R, Wisniewski S, Tisherman SA. Mild hypothermia improves survival after prolonged, traumatic hemorrhagic shock in pigs. The Journal of Trauma. 59: 291-9; discussion 29. PMID 16294067 DOI: 10.1097/01.Ta.0000179445.76729.2C  1
2005 Kochanek PM. Pediatric traumatic brain injury: beyond the guidelines. Current Treatment Options in Neurology. 7: 441-450. PMID 16221367 DOI: 10.1007/S11940-005-0044-9  0.01
2005 Foley LM, Hitchens TK, Kochanek PM, Melick JA, Jackson EK, Ho C. Murine orthostatic response during prolonged vertical studies: effect on cerebral blood flow measured by arterial spin-labeled MRI. Magnetic Resonance in Medicine. 54: 798-806. PMID 16142710 DOI: 10.1002/Mrm.20621  1
2005 Berger RP, Adelson PD, Pierce MC, Dulani T, Cassidy LD, Kochanek PM. Serum neuron-specific enolase, S100B, and myelin basic protein concentrations after inflicted and noninflicted traumatic brain injury in children. Journal of Neurosurgery. 103: 61-8. PMID 16122007 DOI: 10.3171/Ped.2005.103.1.0061  1
2005 Fink EL, Marco CD, Donovan HA, Alexander H, Dixon CE, Jenkins LW, Stange CJ, Kochanek PM, Clark RS. Brief induced hypothermia improves outcome after asphyxial cardiopulmonary arrest in juvenile rats. Developmental Neuroscience. 27: 191-9. PMID 16046854 DOI: 10.1159/000085992  1
2005 Wu X, Kochanek PM. Should we add stem cells to the code cart in resuscitation of heatstroke? Critical Care Medicine. 33: 1458-9. PMID 15942391 DOI: 10.1097/01.Ccm.0000166358.98952.72  1
2005 Kochanek PM, Hendrich KS, Jackson EK, Wisniewski SR, Melick JA, Shore PM, Janesko KL, Zacharia L, Ho C. Characterization of the effects of adenosine receptor agonists on cerebral blood flow in uninjured and traumatically injured rat brain using continuous arterial spin-labeled magnetic resonance imaging. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 1596-612. PMID 15931163 DOI: 10.1038/Sj.Jcbfm.9600154  1
2005 Satchell MA, Lai Y, Kochanek PM, Wisniewski SR, Fink EL, Siedberg NA, Berger RP, DeKosky ST, Adelson PD, Clark RS. Cytochrome c, a biomarker of apoptosis, is increased in cerebrospinal fluid from infants with inflicted brain injury from child abuse. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 919-27. PMID 15744250 DOI: 10.1038/Sj.Jcbfm.9600088  1
2005 Bayir H, Kagan VE, Borisenko GG, Tyurina YY, Janesko KL, Vagni VA, Billiar TR, Williams DL, Kochanek PM. Enhanced oxidative stress in iNOS-deficient mice after traumatic brain injury: support for a neuroprotective role of iNOS. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 673-84. PMID 15716856 DOI: 10.1038/Sj.Jcbfm.9600068  1
2005 Zhang X, Chen Y, Jenkins LW, Kochanek PM, Clark RS. Bench-to-bedside review: Apoptosis/programmed cell death triggered by traumatic brain injury. Critical Care (London, England). 9: 66-75. PMID 15693986 DOI: 10.1186/Cc2950  1
2005 Markovitz BP, Kochanek PM. Show us the evidence? An Evidence-Based Journal Club linking PedsCCM: The Pediatric Critical Care Web Site and Pediatric Critical Care Medicine Pediatric Critical Care Medicine. 6: 253. DOI: 10.1097/01.Pcc.0000160590.96288.42  0.01
2005 Kochanek PM. Pediatric Critical Care Medicine???Unifying our field around the world Pediatric Critical Care Medicine. 6: 1. DOI: 10.1097/00130478-200501000-00001  0.01
2005 Lai Y, Nathaniel PD, Du L, Kochanek PM, Clark RS. Inhibition Of Poly (Adp-Ribose) Polymerase Preserves Bioenergetics In Isolated Mitochondria Under Conditions Of Oxidative Stress.: 62 Critical Care Medicine. 33. DOI: 10.1097/00003246-200512002-00062  1
2005 Bayir H, Clark RS, Zhang XJ, Kagan VE, Feldman KL, Vagni V, Kochanek PM. Mechanisms Of Tyrosine Nitration Of Mnsod After Traumatic Brain Injury.: 61 Critical Care Medicine. 33. DOI: 10.1097/00003246-200512002-00061  1
2005 Fink E, Lai Y, Adelson PD, Kochanek PM, Janesko K, Clark RS, Szabo C. A Novel Method For Quantification Of Poly(Adpribose)-Modified Proteins Validated In Cerebrospinal Fluid From Infants And Children After Traumatic Brain Injury.: 29 Critical Care Medicine. 33. DOI: 10.1097/00003246-200512002-00029  1
2005 Lai Y, Chen Y, Zhang X, Nathaniel PD, Guo F, Jenkins LW, Watkins SC, Kochanek PM, Szabo C, Clark RSB. Poly-ADP-ribosylation is a prevalent post-translational modification of mitochondrial proteins in the brain Journal of Cerebral Blood Flow and Metabolism. 25. DOI: 10.1038/Sj.Jcbfm.9591524.0447  1
2004 Nozari A, Safar P, Wu X, Stezoski WS, Henchir J, Kochanek P, Klain M, Radovsky A, Tisherman SA. Suspended animation can allow survival without brain damage after traumatic exsanguination cardiac arrest of 60 minutes in dogs. The Journal of Trauma. 57: 1266-75. PMID 15625460 DOI: 10.1097/01.Ta.0000124268.24159.8B  1
2004 Nozari A, Safar P, Stezoski SW, Wu X, Henchir J, Radovsky A, Hanson K, Klein E, Kochanek PM, Tisherman SA. Mild hypothermia during prolonged cardiopulmonary cerebral resuscitation increases conscious survival in dogs. Critical Care Medicine. 32: 2110-6. PMID 15483422 DOI: 10.1097/01.Ccm.0000142700.19377.Ae  1
2004 Shore PM, Thomas NJ, Clark RS, Adelson PD, Wisniewski SR, Janesko KL, Bayir H, Jackson EK, Kochanek PM. Continuous versus intermittent cerebrospinal fluid drainage after severe traumatic brain injury in children: effect on biochemical markers. Journal of Neurotrauma. 21: 1113-22. PMID 15453982 DOI: 10.1089/Neu.2004.21.1113  1
2004 DeKosky ST, Abrahamson EE, Taffe KM, Dixon CE, Kochanek PM, Ikonomovic MD. Effects of post-injury hypothermia and nerve growth factor infusion on antioxidant enzyme activity in the rat: implications for clinical therapies. Journal of Neurochemistry. 90: 998-1004. PMID 15287906 DOI: 10.1111/J.1471-4159.2004.02575.X  1
2004 Berger RP, Kochanek PM, Pierce MC. Biochemical markers of brain injury: could they be used as diagnostic adjuncts in cases of inflicted traumatic brain injury? Child Abuse & Neglect. 28: 739-54. PMID 15261469 DOI: 10.1016/J.Chiabu.2004.01.007  1
2004 Du L, Bayir H, Lai Y, Zhang X, Kochanek PM, Watkins SC, Graham SH, Clark RS. Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway. The Journal of Biological Chemistry. 279: 38563-70. PMID 15234982 DOI: 10.1074/Jbc.M405461200  1
2004 DeKosky ST, Taffe KM, Abrahamson EE, Dixon CE, Kochanek PM, Ikonomovic MD. Time course analysis of hippocampal nerve growth factor and antioxidant enzyme activity following lateral controlled cortical impact brain injury in the rat. Journal of Neurotrauma. 21: 491-500. PMID 15165358 DOI: 10.1089/089771504774129838  1
2004 Lai Y, Kochanek PM, Adelson PD, Janesko K, Ruppel RA, Clark RS. Induction of the stress response after inflicted and non-inflicted traumatic brain injury in infants and children. Journal of Neurotrauma. 21: 229-37. PMID 15115598 DOI: 10.1089/089771504322972022  1
2004 Grenvik A, Kochanek PM. The incredible career of Peter J. Safar, MD: the Michelangelo of acute medicine. Critical Care Medicine. 32. PMID 15043225 DOI: 10.1097/01.Ccm.0000110733.48596.4F  1
2004 Shore PM, Jackson EK, Wisniewski SR, Clark RS, Adelson PD, Kochanek PM. Vascular endothelial growth factor is increased in cerebrospinal fluid after traumatic brain injury in infants and children. Neurosurgery. 54: 605-11; discussion 6. PMID 15028134 DOI: 10.1227/01.Neu.0000108642.88724.Db  1
2004 Wagner AK, Bayir H, Ren D, Puccio A, Zafonte RD, Kochanek PM. Relationships between cerebrospinal fluid markers of excitotoxicity, ischemia, and oxidative damage after severe TBI: the impact of gender, age, and hypothermia. Journal of Neurotrauma. 21: 125-36. PMID 15000754 DOI: 10.1089/089771504322778596  1
2004 Bayir H, Marion DW, Puccio AM, Wisniewski SR, Janesko KL, Clark RS, Kochanek PM. Marked gender effect on lipid peroxidation after severe traumatic brain injury in adult patients. Journal of Neurotrauma. 21: 1-8. PMID 14987460 DOI: 10.1089/089771504772695896  1
2004 Fink EL, Alexander H, Marco CD, Dixon CE, Kochanek PM, Jenkins LW, Lai Y, Donovan HA, Hickey RW, Clark RS. Experimental model of pediatric asphyxial cardiopulmonary arrest in rats. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 5: 139-44. PMID 14987343 DOI: 10.1097/01.Pcc.0000112376.29903.8F  1
2004 Kochanek PM. Further growth and development for Pediatric Critical Care Medicine Pediatric Critical Care Medicine. 5: 1. DOI: 10.1097/01.Pcc.0000106668.38377.97  0.01
2004 Bratton SL, Kochanek PM, Chesnut RM, Goldstein B. Caution Should be Exercised When Maintaining a Serum Sodium Level >160 meq/L: The authors reply Critical Care Medicine. 32: 1439-1440. DOI: 10.1097/01.Ccm.0000129111.05213.Cb  1
2004 Kochanek PM, Grenvik A, Schaefer J. A special supplement for a very special man: A celebration of the life of Peter J. Safar, MD Critical Care Medicine. 32. DOI: 10.1097/01.Ccm.0000110741.03076.F0  1
2004 Kochanek PM, Grenvik A, Schaefer J. Introduction to the Proceedings of the Second Annual Safar Symposium Critical Care Medicine. 32. DOI: 10.1097/01.Ccm.0000110735.30860.00  1
2004 Kochanek PM. The Clinical Practice of Critical Care Neurology (Second Edition) Critical Care Medicine. 32: 620-621. DOI: 10.1097/01.Ccm.0000110727.25422.5E  0.01
2004 Chadha MS, Kochanek PM, Jenkins LW, Drabek T, Stezoski J. Rat Hippocampal Degradomics During 30 Minutes Of Global Cerebral Ischemia With & Without Hypothermia Treatment: 360 Critical Care Medicine. 32. DOI: 10.1097/00003246-200412001-00356  1
2004 Fiedor M, Kochanek P, Watson RS, Angus D, Schaefer J. Preliminary Evaluation Of Simbaby, A Novel Pediatric Simulator: 229 Critical Care Medicine. 32. DOI: 10.1097/00003246-200412001-00226  1
2004 Drabek T, Stezoski J, Wu X, Tisherman SA, Stezoski SW, Cochran K, Safar P, Jenkins L, Kochanek PM. Establishment Of A Rat Model Of Suspended Animation With Delayed Resuscitation: A Preliminary Report: 211 Critical Care Medicine. 32. DOI: 10.1097/00003246-200412001-00208  1
Show low-probability matches.