Tammy L. Kielian - Publications

Affiliations: 
University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Neuroimmunology, brain abscess

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Skar GL, Beaver M, Aldrich A, Lagundzin D, Thapa I, Woods N, Ali H, Snowden J, Kielian T. Identification of potential cerebrospinal fluid (CSF) biomarkers to discriminate between infection and sterile inflammation in a rat model of catheter infection. Infection and Immunity. PMID 31262978 DOI: 10.1128/Iai.00311-19  0.4
2019 Zhang W, Guo Y, Kuss M, Shi W, Aldrich A, Untrauer J, Kielian T, Duan B. Platelet-Rich Plasma for the Treatment of Tissue Infection: Preparation and Clinical Evaluation. Tissue Engineering. Part B, Reviews. PMID 30712506 DOI: 10.1089/Ten.Teb.2018.0309  0.4
2019 Burkovetskaya M, Bosch ME, Karpuk N, Fallet R, Kielian T. Caspase 1 activity influences juvenile Batten disease (CLN3) pathogenesis. Journal of Neurochemistry. 148: 652-668. PMID 29873075 DOI: 10.1111/Jnc.14480  1
2016 Aldrich A, Bosch ME, Fallet R, Odvody J, Burkovetskaya M, Rama Rao KV, Cooper JD, Drack AV, Kielian T. Efficacy of phosphodiesterase-4 inhibitors in juvenile Batten disease (CLN3). Annals of Neurology. PMID 27804148 DOI: 10.1002/Ana.24815  1
2016 Bosch ME, Aldrich A, Fallet R, Odvody J, Burkovetskaya M, Schuberth K, Fitzgerald JA, Foust KD, Kielian T. Self-Complementary AAV9 Gene Delivery Partially Corrects Pathology Associated with Juvenile Neuronal Ceroid Lipofuscinosis (CLN3). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 9669-82. PMID 27629717 DOI: 10.1523/Jneurosci.1635-16.2016  1
2016 Sun K, Yajjala VK, Bauer C, Talmon GA, Fischer KJ, Kielian T, Metzger DW. Nox2-derived oxidative stress results in inefficacy of antibiotics against post-influenza S. aureus pneumonia. The Journal of Experimental Medicine. PMID 27526712 DOI: 10.1084/jem.20150514  0.32
2016 Geraets RD, Koh SY, Hastings ML, Kielian T, Pearce DA, Weimer JM. Moving towards effective therapeutic strategies for Neuronal Ceroid Lipofuscinosis. Orphanet Journal of Rare Diseases. 11: 40. PMID 27083890 DOI: 10.1186/S13023-016-0414-2  0.32
2016 Yajjala VK, Thomas VC, Bauer C, Scherr TD, Fischer KJ, Fey PD, Bayles KW, Kielian T, Sun K. Resistance to Acute Macrophage Killing Promotes Airway Fitness of Prevalent Community-Acquired Staphylococcus aureus Strains. Journal of Immunology (Baltimore, Md. : 1950). PMID 27053759 DOI: 10.4049/Jimmunol.1600081  0.32
2015 Poole JA, Wyatt TA, Romberger DJ, Staab E, Simet S, Reynolds SJ, Sisson JH, Kielian T. MyD88 in lung resident cells governs airway inflammatory and pulmonary function responses to organic dust treatment. Respiratory Research. 16: 111. PMID 26376975 DOI: 10.1186/S12931-015-0272-9  0.32
2015 Scherr TD, Hanke ML, Huang O, James DB, Horswill AR, Bayles KW, Fey PD, Torres VJ, Kielian T. Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin. Mbio. 6. PMID 26307164 DOI: 10.1128/Mbio.01021-15  0.32
2015 Heim CE, Vidlak D, Kielian T. Interleukin-10 production by myeloid-derived suppressor cells contributes to bacterial persistence during Staphylococcus aureus orthopedic biofilm infection. Journal of Leukocyte Biology. PMID 26232453 DOI: 10.1189/Jlb.4Vma0315-125Rr  0.32
2015 Heim CE, Vidlak D, Scherr TD, Hartman CW, Garvin KL, Kielian T. IL-12 promotes myeloid-derived suppressor cell recruitment and bacterial persistence during Staphylococcus aureus orthopedic implant infection. Journal of Immunology (Baltimore, Md. : 1950). 194: 3861-72. PMID 25762781 DOI: 10.4049/Jimmunol.1402689  0.32
2015 Mootz JM, Benson MA, Heim CE, Crosby HA, Kavanaugh JS, Dunman PM, Kielian T, Torres VJ, Horswill AR. Rot is a key regulator of Staphylococcus aureus biofilm formation. Molecular Microbiology. 96: 388-404. PMID 25612137 DOI: 10.1111/Mmi.12943  0.32
2015 Bosch ME, Kielian T. Neuroinflammatory paradigms in lysosomal storage diseases Frontiers in Neuroscience. 9. DOI: 10.3389/fnins.2015.00417  0.32
2014 Wang G, Hanke ML, Mishra B, Lushnikova T, Heim CE, Chittezham Thomas V, Bayles KW, Kielian T. Transformation of human cathelicidin LL-37 into selective, stable, and potent antimicrobial compounds. Acs Chemical Biology. 9: 1997-2002. PMID 25061850 DOI: 10.1021/Cb500475Y  0.32
2014 Burkovetskaya M, Karpuk N, Xiong J, Bosch M, Boska MD, Takeuchi H, Suzumura A, Kielian T. Evidence for aberrant astrocyte hemichannel activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL). Plos One. 9: e95023. PMID 24736558 DOI: 10.1371/Journal.Pone.0095023  0.32
2014 Heim CE, Vidlak D, Scherr TD, Kozel JA, Holzapfel M, Muirhead DE, Kielian T. Myeloid-derived suppressor cells contribute to Staphylococcus aureus orthopedic biofilm infection. Journal of Immunology (Baltimore, Md. : 1950). 192: 3778-92. PMID 24646737 DOI: 10.4049/Jimmunol.1303408  0.32
2014 Scherr TD, Heim CE, Morrison JM, Kielian T. Hiding in Plain Sight: Interplay between Staphylococcal Biofilms and Host Immunity. Frontiers in Immunology. 5: 37. PMID 24550921 DOI: 10.3389/Fimmu.2014.00037  0.32
2014 Hanamsagar R, Aldrich A, Kielian T. Critical role for the AIM2 inflammasome during acute CNS bacterial infection. Journal of Neurochemistry. 129: 704-11. PMID 24484406 DOI: 10.1111/Jnc.12669  0.4
2014 Heim CE, Hanke ML, Kielian T. A mouse model of Staphylococcus catheter-associated biofilm infection. Methods in Molecular Biology (Clifton, N.J.). 1106: 183-91. PMID 24222467 DOI: 10.1007/978-1-62703-736-5_17  0.32
2014 Scherr TD, Lindgren KE, Schaeffer CR, Hanke ML, Hartman CW, Kielian T. Mouse model of post-arthroplasty Staphylococcus epidermidis joint infection. Methods in Molecular Biology (Clifton, N.J.). 1106: 173-81. PMID 24222466 DOI: 10.1007/978-1-62703-736-5_16  0.32
2014 Bosch M, Kielian T. Hemichannels in neurodegenerative diseases: Is there a link to pathology? Frontiers in Cellular Neuroscience. 8. DOI: 10.3389/Fncel.2014.00242  0.32
2014 Hanamsagar R, Cardona SM, Kielian T, Cardona AE. Roles in immune responses Microglia in Health and Disease. 115-144. DOI: 10.1007/978-1-4939-1429-6_5  0.32
2013 Snowden JN, Beaver M, Beenken K, Smeltzer M, Horswill AR, Kielian T. Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation. Plos One. 8: e84089. PMID 24386336 DOI: 10.1371/Journal.Pone.0084089  0.32
2013 Scherr TD, Roux CM, Hanke ML, Angle A, Dunman PM, Kielian T. Global transcriptome analysis of Staphylococcus aureus biofilms in response to innate immune cells. Infection and Immunity. 81: 4363-76. PMID 24042108 DOI: 10.1128/Iai.00819-13  0.32
2013 Xiong J, Kielian T. Microglia in juvenile neuronal ceroid lipofuscinosis are primed toward a pro-inflammatory phenotype Journal of Neurochemistry. 127: 245-258. PMID 23919525 DOI: 10.1111/Jnc.12385  0.32
2013 Cheatle J, Aldrich A, Thorell WE, Boska MD, Kielian T. Compartmentalization of immune responses during Staphylococcus aureus cranial bone flap infection. The American Journal of Pathology. 183: 450-8. PMID 23747950 DOI: 10.1016/J.Ajpath.2013.04.031  0.4
2013 Bauer C, Kielian T, Wyatt TA, Romberger DJ, West WW, Gleason AM, Poole JA. Myeloid differentiation factor 88-dependent signaling is critical for acute organic dust-induced airway inflammation in mice. American Journal of Respiratory Cell and Molecular Biology. 48: 781-9. PMID 23492189 DOI: 10.1165/Rcmb.2012-0479Oc  0.32
2013 Hanke ML, Heim CE, Angle A, Sanderson SD, Kielian T. Targeting macrophage activation for the prevention and treatment of Staphylococcus aureus biofilm infections. Journal of Immunology (Baltimore, Md. : 1950). 190: 2159-68. PMID 23365077 DOI: 10.4049/Jimmunol.1202348  0.32
2013 Hanke ML, Heim CE, Angle A, Sanderson SD, Kielian T. Targeting macrophage activation for the prevention and treatment of Staphylococcus aureus biofilm infections (Journal of Immunology (2013) 190, (2159-2168)) Journal of Immunology. 190: 6709-6710. DOI: 10.4049/Jimmunol.1390029  0.32
2012 Nuxoll AS, Halouska SM, Sadykov MR, Hanke ML, Bayles KW, Kielian T, Powers R, Fey PD. CcpA regulates arginine biosynthesis in Staphylococcus aureus through repression of proline catabolism. Plos Pathogens. 8: e1003033. PMID 23209408 DOI: 10.1371/Journal.Ppat.1003033  0.32
2012 Poole JA, Gleason AM, Bauer C, West WW, Alexis N, Reynolds SJ, Romberger DJ, Kielian T. αβ T cells and a mixed Th1/Th17 response are important in organic dust-induced airway disease. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. 109: 266-273.e2. PMID 23010233 DOI: 10.1016/J.Anai.2012.06.015  0.32
2012 Hanke ML, Kielian T. Deciphering mechanisms of staphylococcal biofilm evasion of host immunity. Frontiers in Cellular and Infection Microbiology. 2: 62. PMID 22919653 DOI: 10.3389/Fcimb.2012.00062  0.32
2012 Hanke ML, Angle A, Kielian T. MyD88-dependent signaling influences fibrosis and alternative macrophage activation during Staphylococcus aureus biofilm infection. Plos One. 7: e42476. PMID 22879997 DOI: 10.1371/Journal.Pone.0042476  0.32
2012 Poole JA, Gleason AM, Bauer C, West WW, Alexis N, van Rooijen N, Reynolds SJ, Romberger DJ, Kielian TL. CD11c(+)/CD11b(+) cells are critical for organic dust-elicited murine lung inflammation. American Journal of Respiratory Cell and Molecular Biology. 47: 652-9. PMID 22822029 DOI: 10.1165/Rcmb.2012-0095Oc  0.32
2012 Snowden JN, Beaver M, Smeltzer MS, Kielian T. Biofilm-infected intracerebroventricular shunts elicit inflammation within the central nervous system. Infection and Immunity. 80: 3206-14. PMID 22753376 DOI: 10.1128/Iai.00645-12  0.32
2012 Hanamsagar R, Hanke ML, Kielian T. Toll-like receptor (TLR) and inflammasome actions in the central nervous system. Trends in Immunology. 33: 333-42. PMID 22521509 DOI: 10.1016/J.It.2012.03.001  0.32
2012 Menousek J, Mishra B, Hanke ML, Heim CE, Kielian T, Wang G. Database screening and in vivo efficacy of antimicrobial peptides against methicillin-resistant Staphylococcus aureus USA300. International Journal of Antimicrobial Agents. 39: 402-6. PMID 22445495 DOI: 10.1016/J.Ijantimicag.2012.02.003  0.32
2012 Liu Y, Sajja BR, Uberti MG, Gendelman HE, Kielian T, Boska MD. Landmark optimization using local curvature for point-based nonlinear rodent brain image registration. International Journal of Biomedical Imaging. 2012: 635207. PMID 21966289 DOI: 10.1155/2012/635207  0.32
2012 Holley MM, Zhang Y, Lehrmann E, Wood WH, Becker KG, Kielian T. Toll-like receptor 2 (TLR2)-TLR9 crosstalk dictates IL-12 family cytokine production in microglia. Glia. 60: 29-42. PMID 21901759 DOI: 10.1002/Glia.21243  0.32
2011 Hanamsagar R, Torres V, Kielian T. Inflammasome activation and IL-1β/IL-18 processing are influenced by distinct pathways in microglia. Journal of Neurochemistry. 119: 736-48. PMID 21913925 DOI: 10.1111/J.1471-4159.2011.07481.X  0.32
2011 Hanke ML, Kielian T. Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential. Clinical Science (London, England : 1979). 121: 367-87. PMID 21745188 DOI: 10.1042/Cs20110164  0.32
2011 Poole JA, Kielian T, Wyatt TA, Gleason AM, Stone J, Palm K, West WW, Romberger DJ. Organic dust augments nucleotide-binding oligomerization domain expression via an NF-{kappa}B pathway to negatively regulate inflammatory responses. American Journal of Physiology. Lung Cellular and Molecular Physiology. 301: L296-306. PMID 21665963 DOI: 10.1152/Ajplung.00086.2011  0.32
2011 Thurlow LR, Hanke ML, Fritz T, Angle A, Aldrich A, Williams SH, Engebretsen IL, Bayles KW, Horswill AR, Kielian T. Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 186: 6585-96. PMID 21525381 DOI: 10.4049/Jimmunol.1002794  0.32
2011 Poole JA, Wyatt TA, Kielian T, Oldenburg P, Gleason AM, Bauer A, Golden G, West WW, Sisson JH, Romberger DJ. Toll-like receptor 2 regulates organic dust-induced airway inflammation. American Journal of Respiratory Cell and Molecular Biology. 45: 711-9. PMID 21278324 DOI: 10.1165/Rcmb.2010-0427Oc  0.32
2011 Karpuk N, Burkovetskaya M, Fritz T, Angle A, Kielian T. Neuroinflammation leads to region-dependent alterations in astrocyte gap junction communication and hemichannel activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 414-25. PMID 21228152 DOI: 10.1523/Jneurosci.5247-10.2011  0.04
2009 Garg S, Nichols JR, Esen N, Liu S, Phulwani NK, Syed MM, Wood WH, Zhang Y, Becker KG, Aldrich A, Kielian T. MyD88 expression by CNS-resident cells is pivotal for eliciting protective immunity in brain abscesses. Asn Neuro. 1. PMID 19570030 DOI: 10.1042/An20090004  0.32
2009 Nichols JR, Aldrich AL, Mariani MM, Vidlak D, Esen N, Kielian T. TLR2 deficiency leads to increased Th17 infiltrates in experimental brain abscesses Journal of Immunology. 182: 7119-7130. PMID 19454709 DOI: 10.4049/Jimmunol.0802656  0.32
2006 Phulwani NK, Feinstein DL, Gavrilyuk V, Akar C, Kielian T. 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) and ciglitazone modulate Staphylococcus aureus-dependent astrocyte activation primarily through a PPAR-gamma-independent pathway. Journal of Neurochemistry. 99: 1389-1402. PMID 17074064 DOI: 10.1111/J.1471-4159.2006.04183.X  0.32
2006 Konat GW, Kielian T, Marriott I. The role of Toll-like receptors in CNS response to microbial challenge. Journal of Neurochemistry. 99: 1-12. PMID 16899072 DOI: 10.1111/J.1471-4159.2006.04076.X  0.32
2004 Esen N, Tanga FY, DeLeo JA, Kielian T. Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus. Journal of Neurochemistry. 88: 746-58. PMID 14720224 DOI: 10.1046/J.1471-4159.2003.02202.X  0.32
2002 Kielian T, van Rooijen N, Hickey WF. MCP-1 expression in CNS-1 astrocytoma cells: implications for macrophage infiltration into tumors in vivo. Journal of Neuro-Oncology. 56: 1-12. PMID 11949821 DOI: 10.1023/A:1014495613455  0.32
2001 Kielian T, Cheung A, Hickey WF. Diminished virulence of an alpha-toxin mutant of Staphylococcus aureus in experimental brain abscesses. Infection and Immunity. 69: 6902-11. PMID 11598065 DOI: 10.1128/Iai.69.11.6902-6911.2001  0.32
2001 Kielian T, Barry B, Hickey WF. CXC chemokine receptor-2 ligands are required for neutrophil-mediated host defense in experimental brain abscesses. Journal of Immunology (Baltimore, Md. : 1950). 166: 4634-43. PMID 11254722 DOI: 10.4049/Jimmunol.166.7.4634  0.32
2000 Kielian T, Hickey WF. Proinflammatory cytokine, chemokine, and cellular adhesion molecule expression during the acute phase of experimental brain abscess development. The American Journal of Pathology. 157: 647-58. PMID 10934167 DOI: 10.1016/S0002-9440(10)64575-0  0.32
1999 Kielian T, Hickey WF. Inflammatory thoughts about glioma gene therapy. Nature Medicine. 5: 1237-8. PMID 10545984 DOI: 10.1038/15188  0.32
1999 Kielian T, Nagai E, Ikubo A, Rasmussen CA, Suzuki T. Granulocyte/macrophage-colony-stimulating factor released by adenovirally transduced CT26 cells leads to the local expression of macrophage inflammatory protein 1alpha and accumulation of dendritic cells at vaccination sites in vivo. Cancer Immunology, Immunotherapy : Cii. 48: 123-31. PMID 10414466 DOI: 10.1007/s002620050556  0.32
1995 Dritz SS, Shi J, Kielian TL, Goodband RD, Nelssen JL, Tokach MD, Chengappa MM, Smith JE, Blecha F. Influence of dietary beta-glucan on growth performance, nonspecific immunity, and resistance to Streptococcus suis infection in weanling pigs. Journal of Animal Science. 73: 3341-50. PMID 8586593 DOI: 10.2527/1995.73113341X  0.32
1995 Kielian TL, Blecha F. CD14 and other recognition molecules for lipopolysaccharide: a review. Immunopharmacology. 29: 187-205. PMID 7542643 DOI: 10.1016/0162-3109(95)00003-C  0.32
1995 Kielian TL, Ross CR, McVey DS, Chapes SK, Blecha F. Lipopolysaccharide modulation of a CD14-like molecule on porcine alveolar macrophages. Journal of Leukocyte Biology. 57: 581-6. PMID 7536786 DOI: 10.1002/Jlb.57.4.581  0.32
1994 Blecha F, Kielian T, McVey DS, Lunney JK, Walker K, Stokes CR, Stevens K, Kim YB, Chu RM, Chen TS, Murtaugh MP, Choi C, Molitor TW, McCullough K, Pescovitz MD. Workshop studies on monoclonal antibodies reactive against porcine myeloid cells Veterinary Immunology and Immunopathology. 43: 269-272. PMID 7856058 DOI: 10.1016/0165-2427(94)90147-3  0.32
1994 Lunney JK, Walker K, Goldman T, Aasted B, Bianchi A, Binns R, Licence S, Bischof R, Brandon M, Blecha F, Kielian TL, McVey DS, Chu RM, Carr M, Howard C, et al. Overview of the First International Workshop to Define Swine Leukocyte Cluster of Differentiation (CD) Antigens Veterinary Immunology and Immunopathology. 43: 193-206. PMID 7856053 DOI: 10.1016/0165-2427(94)90136-8  0.32
1994 Kielian T, McVey DS, Davis WC, Kim YB, Blecha F. Competitive binding analysis of monoclonal antibodies reactive with porcine alveolar macrophages using anti-CD14 and anti-CD18 Veterinary Immunology and Immunopathology. 43: 273-278. PMID 7531910 DOI: 10.1016/0165-2427(94)90148-1  0.32
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