| Year |
Citation |
Score |
| 2015 |
Shoemark DK, Williams C, Fahey MS, Watson JJ, Tyler SJ, Scoltock SJ, Ellis RZ, Wickenden E, Burton AJ, Hemmings JL, Bailey CD, Dawbarn D, Jane DE, Willis CL, Sessions RB, ... Allen SJ, et al. Design and nuclear magnetic resonance (NMR) structure determination of the second extracellular immunoglobulin tyrosine kinase A (TrkAIg2) domain construct for binding site elucidation in drug discovery. Journal of Medicinal Chemistry. 58: 767-77. PMID 25454499 DOI: 10.1021/Jm501307E |
0.634 |
|
| 2013 |
Allen SJ, Watson JJ, Shoemark DK, Barua NU, Patel NK. GDNF, NGF and BDNF as therapeutic options for neurodegeneration. Pharmacology & Therapeutics. 138: 155-75. PMID 23348013 DOI: 10.1016/j.pharmthera.2013.01.004 |
0.344 |
|
| 2013 |
Frias B, Allen S, Dawbarn D, Charrua A, Cruz F, Cruz CD. Brain-derived neurotrophic factor, acting at the spinal cord level, participates in bladder hyperactivity and referred pain during chronic bladder inflammation. Neuroscience. 234: 88-102. PMID 23313710 DOI: 10.1016/J.Neuroscience.2012.12.044 |
0.603 |
|
| 2011 |
Allen SJ, Watson JJ, Dawbarn D. The neurotrophins and their role in Alzheimer's disease. Current Neuropharmacology. 9: 559-73. PMID 22654716 DOI: 10.2174/157015911798376190 |
0.663 |
|
| 2010 |
McNamee KE, Burleigh A, Gompels LL, Feldmann M, Allen SJ, Williams RO, Dawbarn D, Vincent TL, Inglis JJ. Treatment of murine osteoarthritis with TrkAd5 reveals a pivotal role for nerve growth factor in non-inflammatory joint pain. Pain. 149: 386-92. PMID 20350782 DOI: 10.1016/J.Pain.2010.03.002 |
0.584 |
|
| 2010 |
Pinto R, Frias B, Allen S, Dawbarn D, McMahon SB, Cruz F, Cruz CD. Sequestration of brain derived nerve factor by intravenous delivery of TrkB-Ig2 reduces bladder overactivity and noxious input in animals with chronic cystitis. Neuroscience. 166: 907-16. PMID 20079809 DOI: 10.1016/J.Neuroscience.2010.01.015 |
0.611 |
|
| 2009 |
Masoudi R, Ioannou MS, Coughlin MD, Pagadala P, Neet KE, Clewes O, Allen SJ, Dawbarn D, Fahnestock M. Biological activity of nerve growth factor precursor is dependent upon relative levels of its receptors. The Journal of Biological Chemistry. 284: 18424-33. PMID 19389705 DOI: 10.1074/Jbc.M109.007104 |
0.681 |
|
| 2008 |
Watson JJ, Allen SJ, Dawbarn D. Targeting nerve growth factor in pain: what is the therapeutic potential? Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. 22: 349-59. PMID 18998753 DOI: 10.2165/0063030-200822060-00002 |
0.642 |
|
| 2008 |
Clewes O, Fahey MS, Tyler SJ, Watson JJ, Seok H, Catania C, Cho K, Dawbarn D, Allen SJ. Human ProNGF: biological effects and binding profiles at TrkA, P75NTR and sortilin. Journal of Neurochemistry. 107: 1124-35. PMID 18808449 DOI: 10.1111/J.1471-4159.2008.05698.X |
0.65 |
|
| 2007 |
Hatchett CS, Tyler S, Armstrong D, Dawbarn D, Allen SJ. Familial Alzheimer's disease presenilin 1 mutation M146V increases gamma secretase cutting of p75NTR in vitro. Brain Research. 1147: 248-55. PMID 17349981 DOI: 10.1016/J.Brainres.2007.02.002 |
0.641 |
|
| 2006 |
Nassenstein C, Dawbarn D, Pollock K, Allen SJ, Erpenbeck VJ, Spies E, Krug N, Braun A. Pulmonary distribution, regulation, and functional role of Trk receptors in a murine model of asthma. The Journal of Allergy and Clinical Immunology. 118: 597-605. PMID 16950277 DOI: 10.1016/J.Jaci.2006.04.052 |
0.608 |
|
| 2006 |
Dawbarn D, Fahey M, Watson J, Tyler S, Shoemark D, Sessions R, Zhang R, Brady L, Willis C, Allen SJ. NGF receptor TrkAd5: therapeutic agent and drug design target. Biochemical Society Transactions. 34: 587-90. PMID 16856868 DOI: 10.1042/Bst0340587 |
0.663 |
|
| 2006 |
Allen SJ, Dawbarn D. Clinical relevance of the neurotrophins and their receptors. Clinical Science (London, England : 1979). 110: 175-91. PMID 16411894 DOI: 10.1042/Cs20050161 |
0.68 |
|
| 2006 |
Watson JJ, Fahey MS, van den Worm E, Engels F, Nijkamp FP, Stroemer P, McMahon S, Allen SJ, Dawbarn D. TrkAd5: A novel therapeutic agent for treatment of inflammatory pain and asthma. The Journal of Pharmacology and Experimental Therapeutics. 316: 1122-9. PMID 16284276 DOI: 10.1124/Jpet.105.095844 |
0.637 |
|
| 2006 |
Love S, Siew LK, Dawbarn D, Wilcock GK, Ben-Shlomo Y, Allen SJ. Premorbid effects of APOE on synaptic proteins in human temporal neocortex. Neurobiology of Aging. 27: 797-803. PMID 15979210 DOI: 10.1016/J.Neurobiolaging.2005.04.008 |
0.598 |
|
| 2005 |
Hu VY, Zvara P, Dattilio A, Redman TL, Allen SJ, Dawbarn D, Stroemer RP, Vizzard MA. Decrease in bladder overactivity with REN1820 in rats with cyclophosphamide induced cystitis. The Journal of Urology. 173: 1016-21. PMID 15711368 DOI: 10.1097/01.Ju.0000155170.15023.E5 |
0.593 |
|
| 2004 |
Siew LK, Love S, Dawbarn D, Wilcock GK, Allen SJ. Measurement of pre- and post-synaptic proteins in cerebral cortex: effects of post-mortem delay. Journal of Neuroscience Methods. 139: 153-9. PMID 15488227 DOI: 10.1016/J.Jneumeth.2004.04.020 |
0.571 |
|
| 2003 |
Dawbarn D, Allen SJ. Neurotrophins and neurodegeneration. Neuropathology and Applied Neurobiology. 29: 211-30. PMID 12787319 DOI: 10.1046/j.1365-2990.2003.00487.x |
0.673 |
|
| 2002 |
Tyler SJ, Dawbarn D, Wilcock GK, Allen SJ. alpha- and beta-secretase: profound changes in Alzheimer's disease. Biochemical and Biophysical Research Communications. 299: 373-6. PMID 12445809 DOI: 10.1016/S0006-291X(02)02635-9 |
0.587 |
|
| 2002 |
Naylor RL, Robertson AG, Allen SJ, Sessions RB, Clarke AR, Mason GG, Burston JJ, Tyler SJ, Wilcock GK, Dawbarn D. A discrete domain of the human TrkB receptor defines the binding sites for BDNF and NT-4. Biochemical and Biophysical Research Communications. 291: 501-7. PMID 11855816 DOI: 10.1006/Bbrc.2002.6468 |
0.647 |
|
| 2001 |
Banfield MJ, Naylor RL, Robertson AG, Allen SJ, Dawbarn D, Brady RL. Specificity in Trk receptor:neurotrophin interactions: the crystal structure of TrkB-d5 in complex with neurotrophin-4/5. Structure (London, England : 1993). 9: 1191-9. PMID 11738045 DOI: 10.1016/S0969-2126(01)00681-5 |
0.644 |
|
| 2001 |
Robertson AG, Banfield MJ, Allen SJ, Dando JA, Mason GG, Tyler SJ, Bennett GS, Brain SD, Clarke AR, Naylor RL, Wilcock GK, Brady RL, Dawbarn D. Identification and structure of the nerve growth factor binding site on TrkA. Biochemical and Biophysical Research Communications. 282: 131-41. PMID 11263982 DOI: 10.1006/Bbrc.2001.4462 |
0.67 |
|
| 2001 |
Allen SJ, Robertson AG, Tyler SJ, Wilcock GK, Dawbarn D. Recombinant human nerve growth factor for clinical trials: protein expression, purification, stability and characterisation of binding to infusion pumps. Journal of Biochemical and Biophysical Methods. 47: 239-55. PMID 11245895 DOI: 10.1016/S0165-022X(01)00134-8 |
0.672 |
|
| 2001 |
Fahey MS, Dawbarn D, Allen SJ, Paterson IC, Prime SS. Expression of recombinant extracellular domain of the type II transforming growth factor-beta receptor: utilization in a modified enzyme-linked immunoabsorbent assay to screen TGF-beta agonists and antagonists. Analytical Biochemistry. 290: 272-6. PMID 11237329 DOI: 10.1006/abio.2000.4948 |
0.574 |
|
| 2000 |
O'Meara G, Coumis U, Ma SY, Kehr J, Mahoney S, Bacon A, Allen SJ, Holmes F, Kahl U, Wang FH, Kearns IR, Ove-Ogren S, Dawbarn D, Mufson EJ, Davies C, et al. Galanin regulates the postnatal survival of a subset of basal forebrain cholinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 97: 11569-74. PMID 11016971 DOI: 10.1073/Pnas.210254597 |
0.618 |
|
| 2000 |
Smith SK, Anderson HA, Yu G, Robertson AG, Allen SJ, Tyler SJ, Naylor RL, Mason G, Wilcock GW, Roche PA, Fraser PE, Dawbarn D. Identification of syntaxin 1A as a novel binding protein for presenilin-1. Brain Research. Molecular Brain Research. 78: 100-7. PMID 10891589 DOI: 10.1016/S0169-328X(00)00079-6 |
0.583 |
|
| 1999 |
Allen SJ, Wilcock GK, Dawbarn D. Profound and selective loss of catalytic TrkB immunoreactivity in Alzheimer's disease. Biochemical and Biophysical Research Communications. 264: 648-51. PMID 10543986 DOI: 10.1006/Bbrc.1999.1561 |
0.65 |
|
| 1997 |
Allen SJ, MacGowan SH, Tyler S, Wilcock GK, Robertson AG, Holden PH, Smith SK, Dawbarn D. Reduced cholinergic function in normal and Alzheimer's disease brain is associated with apolipoprotein E4 genotype. Neuroscience Letters. 239: 33-6. PMID 9547165 DOI: 10.1016/S0304-3940(97)00872-0 |
0.605 |
|
| 1997 |
Holden PH, Asopa V, Robertson AG, Clarke AR, Tyler S, Bennett GS, Brain SD, Wilcock GK, Allen SJ, Smith SK, Dawbarn D. Immunoglobulin-like domains define the nerve growth factor binding site of the TrkA receptor. Nature Biotechnology. 15: 668-72. PMID 9219271 DOI: 10.1038/Nbt0797-668 |
0.664 |
|
| 1994 |
Allen SJ, Dawbarn D, Eckford SD, Wilcock GK, Ashcroft M, Colebrook SM, Feeney R, MacGowan SH. Cloning of a non-catalytic form of human trkB and distribution of messenger RNA for trkB in human brain. Neuroscience. 60: 825-34. PMID 7936202 DOI: 10.1016/0306-4522(94)90507-X |
0.599 |
|
| 1991 |
Allen SJ, MacGowan SH, Treanor JJ, Feeney R, Wilcock GK, Dawbarn D. Normal beta-NGF content in Alzheimer's disease cerebral cortex and hippocampus. Neuroscience Letters. 131: 135-9. PMID 1791973 DOI: 10.1016/0304-3940(91)90354-V |
0.652 |
|
| 1991 |
Treanor JJ, Dawbarn D, Allen SJ, MacGowan SH, Wilcock GK. Low affinity nerve growth factor receptor binding in normal and Alzheimer's disease basal forebrain. Neuroscience Letters. 121: 73-6. PMID 1708488 DOI: 10.1016/0304-3940(91)90652-A |
0.685 |
|
| 1991 |
Allen SJ, MacGowan SH, Treanor JJS, Feeney R, Wilcock GK, Dawbarn D. Normal β-NGF content in Alzheimer's disease cerebral cortex and hippocampus Neuroscience Letters. 131: 135-139. DOI: 10.1016/0304-3940(91)90354-V |
0.608 |
|
| 1990 |
Allen SJ, Dawbarn D, Macgowan SH, Wikock GK, Treanor JJS, Moss TH. Quantitative morphometric analysis of basal forebrain neurons expressing β-nerve growth factor receptors in normal and alzheimer’s disease brains Dementia and Geriatric Cognitive Disorders. 1: 125-137. DOI: 10.1159/000107132 |
0.659 |
|
| 1989 |
Allen SJ, Dawbarn D, Spillantini MG, Goedert M, Wilcock GK, Moss TH, Semenenko FM. Distribution of beta-nerve growth factor receptors in the human basal forebrain. The Journal of Comparative Neurology. 289: 626-40. PMID 2556457 DOI: 10.1002/Cne.902890408 |
0.667 |
|
| 1988 |
Allen SJ, Dawbarn D, Wilcock GK. Morphometric immunochemical analysis of neurons in the nucleus basalis of Meynert in Alzheimer's disease. Brain Research. 454: 275-81. PMID 3409011 DOI: 10.1016/0006-8993(88)90827-X |
0.601 |
|
| 1988 |
Dawbarn D, Allen SJ, Semenenko FM. Coexistence of choline acetyltransferase and nerve growth factor receptors in the rat basal forebrain. Neuroscience Letters. 94: 138-44. PMID 2853851 DOI: 10.1016/0304-3940(88)90284-4 |
0.667 |
|
| 1988 |
Dawbarn D, Allen SJ, Semenenko FM. Immunohistochemical localization of beta-nerve growth factor receptors in the forebrain of the rat. Brain Research. 440: 185-9. PMID 2833990 DOI: 10.1016/0006-8993(88)91175-4 |
0.637 |
|
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