Year |
Citation |
Score |
2020 |
Bohlen MO, McCown TJ, Powell SK, El-Nahal H, Daw T, Basso MA, Sommer MA, Samulski RJ. AAV Capsid-Promoter Interactions in the Brain Translate from Rat to the Non-Human Primate. Human Gene Therapy. PMID 32940068 DOI: 10.1089/hum.2020.196 |
0.418 |
|
2020 |
Powell SK, Samulski RJ, McCown TJ. AAV Capsid-Promoter Interactions Determine CNS Cell-Selective Gene Expression In Vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32213322 DOI: 10.1016/j.ymthe.2020.03.007 |
0.461 |
|
2017 |
Mandel RJ, Marmion DJ, Kirik D, Chu Y, Heindel C, McCown T, Gray SJ, Kordower JH. Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates. Acta Neuropathologica Communications. 5: 47. PMID 28619074 DOI: 10.1186/S40478-017-0451-7 |
0.31 |
|
2017 |
Weinberg MS, Criswell HE, Powell SK, Bhatt AP, McCown TJ. Viral Vector Reprogramming of Adult Resident Striatal Oligodendrocytes into Functional Neurons. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28202388 DOI: 10.1016/J.Ymthe.2017.01.016 |
0.306 |
|
2016 |
Powell SK, Khan N, Parker CL, Samulski RJ, Matsushima G, Gray SJ, McCown TJ. Characterization of a novel adeno-associated viral vector with preferential oligodendrocyte tropism. Gene Therapy. PMID 27628693 DOI: 10.1038/Gt.2016.62 |
0.481 |
|
2015 |
Hu P, Li Y, Sands MS, McCown T, Kafri T. Generation of a stable packaging cell line producing high-titer PPT-deleted integration-deficient lentiviral vectors. Molecular Therapy. Methods & Clinical Development. 2: 15025. PMID 26229972 DOI: 10.1038/Mtm.2015.25 |
0.407 |
|
2015 |
Powell SK, Khan N, Parker C, Jude Samulski R, Matsushima G, Gray SJ, McCown TJ. 306. Characterization of a Novel Adeno-Associated Viral Vector with Preferential Oligodendrocyte Tropism Molecular Therapy. 23: S123-S124. DOI: 10.1016/S1525-0016(16)33915-6 |
0.335 |
|
2014 |
Kantor B, McCown T, Leone P, Gray SJ. Clinical applications involving CNS gene transfer. Advances in Genetics. 87: 71-124. PMID 25311921 DOI: 10.1016/B978-0-12-800149-3.00002-0 |
0.459 |
|
2013 |
Weinberg MS, Blake BL, McCown TJ. Opposing actions of hippocampus TNFα receptors on limbic seizure susceptibility. Experimental Neurology. 247: 429-37. PMID 23333565 DOI: 10.1016/j.expneurol.2013.01.011 |
0.305 |
|
2013 |
Weinberg MS, Samulski RJ, McCown TJ. Adeno-associated virus (AAV) gene therapy for neurological disease. Neuropharmacology. 69: 82-8. PMID 22465202 DOI: 10.1016/j.neuropharm.2012.03.004 |
0.37 |
|
2013 |
Weinberg MS, McCown TJ. Current prospects and challenges for epilepsy gene therapy. Experimental Neurology. 244: 27-35. PMID 22008258 DOI: 10.1016/j.expneurol.2011.10.003 |
0.455 |
|
2011 |
Gray SJ, Choi VW, Asokan A, Haberman RA, McCown TJ, Samulski RJ. Production of recombinant adeno-associated viral vectors and use in in vitro and in vivo administration. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.17. PMID 21971848 DOI: 10.1002/0471142301.Ns0417S57 |
0.769 |
|
2011 |
Weinberg MS, Blake BL, Samulski RJ, McCown TJ. The influence of epileptic neuropathology and prior peripheral immunity on CNS transduction by rAAV2 and rAAV5. Gene Therapy. 18: 961-8. PMID 21490684 DOI: 10.1038/Gt.2011.49 |
0.46 |
|
2011 |
Gray SJ, Foti SB, Schwartz JW, Bachaboina L, Taylor-Blake B, Coleman J, Ehlers MD, Zylka MJ, McCown TJ, Samulski RJ. Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors. Human Gene Therapy. 22: 1143-53. PMID 21476867 DOI: 10.1089/Hum.2010.245 |
0.727 |
|
2011 |
McCown TJ. Adeno-Associated Virus (AAV) Vectors in the CNS. Current Gene Therapy. 11: 181-8. PMID 21453285 |
0.467 |
|
2011 |
Kantor B, Bayer M, Ma H, Samulski J, Li C, McCown T, Kafri T. Notable reduction in illegitimate integration mediated by a PPT-deleted, nonintegrating lentiviral vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 547-56. PMID 21157436 DOI: 10.1038/Mt.2010.277 |
0.516 |
|
2010 |
Gray SJ, Blake BL, Criswell HE, Nicolson SC, Samulski RJ, McCown TJ. Directed Evolution of a Novel Adeno-associated Virus (AAV) Vector That Crosses the Seizure-compromised Blood-Brain Barrier (BBB). Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 570-578. PMID 28182880 DOI: 10.1038/mt.2009.292 |
0.363 |
|
2010 |
McCown TJ. The future of epilepsy treatment: focus on adeno-associated virus vector gene therapy. Drug News & Perspectives. 23: 281-6. PMID 20603651 DOI: 10.1358/dnp.2010.23.5.1468393 |
0.45 |
|
2010 |
Gray SJ, Blake BL, Criswell HE, Nicolson SC, Samulski RJ, McCown TJ, Li W. Directed evolution of a novel adeno-associated virus (AAV) vector that crosses the seizure-compromised blood-brain barrier (BBB). Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 570-8. PMID 20040913 DOI: 10.1038/Mt.2009.292 |
0.363 |
|
2010 |
Koh MT, Haberman RP, Foti S, McCown TJ, Gallagher M. Treatment strategies targeting excess hippocampal activity benefit aged rats with cognitive impairment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1016-25. PMID 20032967 DOI: 10.1038/Npp.2009.207 |
0.679 |
|
2009 |
Foti SB, Samulski RJ, McCown TJ. Delivering multiple gene products in the brain from a single adeno-associated virus vector. Gene Therapy. 16: 1314-9. PMID 19727140 DOI: 10.1038/Gt.2009.106 |
0.76 |
|
2009 |
McCown TJ. Adeno-associated virus vector-mediated expression and constitutive secretion of galanin suppresses limbic seizure activity. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 6: 307-11. PMID 19332324 DOI: 10.1016/j.nurt.2009.01.004 |
0.473 |
|
2009 |
Foti SB, Russek SJ, Brooks-Kayal AR, McCown TJ. Viral vector gene therapy for epilepsy Neuromethods. 40: 235-250. DOI: 10.1007/978-1-60327-263-6_13 |
0.744 |
|
2008 |
Li W, Asokan A, Wu Z, Van Dyke T, DiPrimio N, Johnson JS, Govindaswamy L, Agbandje-McKenna M, Leichtle S, Eugene Redmond D, McCown TJ, Petermann KB, Sharpless NE, Samulski RJ. Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1252-1260. PMID 28178482 DOI: 10.1038/Mt.2008.100 |
0.308 |
|
2008 |
Bayer M, Kantor B, Cockrell A, Ma H, Zeithaml B, Li X, McCown T, Kafri T. A large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1968-76. PMID 18797449 DOI: 10.1038/Mt.2008.199 |
0.419 |
|
2008 |
Li W, Asokan A, Wu Z, Van Dyke T, DiPrimio N, Johnson JS, Govindaswamy L, Agbandje-McKenna M, Leichtle S, Redmond DE, McCown TJ, Petermann KB, Sharpless NE, Samulski RJ. Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1252-60. PMID 18500254 DOI: 10.1038/mt.2008.100 |
0.308 |
|
2008 |
Zhou X, Zeng X, Fan Z, Li C, McCown T, Samulski RJ, Xiao X. Adeno-associated virus of a single-polarity DNA genome is capable of transduction in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 494-9. PMID 18180769 DOI: 10.1038/Sj.Mt.6300397 |
0.431 |
|
2007 |
Foti S, Haberman RP, Samulski RJ, McCown TJ. Adeno-associated virus-mediated expression and constitutive secretion of NPY or NPY13-36 suppresses seizure activity in vivo. Gene Therapy. 14: 1534-6. PMID 17713567 DOI: 10.1038/Sj.Gt.3303013 |
0.741 |
|
2006 |
Choi VW, Asokan A, Haberman RA, McCown TJ, Samulski RJ. Production of recombinant adeno-associated viral vectors and use for in vitro and in vivo administration. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.17. PMID 18428636 DOI: 10.1002/0471142301.ns0417s35 |
0.773 |
|
2006 |
McCown TJ. Adeno-associated virus-mediated expression and constitutive secretion of galanin suppresses limbic seizure activity in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 63-8. PMID 16730475 DOI: 10.1016/j.ymthe.2006.04.004 |
0.387 |
|
2005 |
McCown TJ. Adeno-associated virus (AAV) vectors in the CNS. Current Gene Therapy. 5: 333-8. PMID 15975010 DOI: 10.2174/1566523054064995 |
0.475 |
|
2005 |
Cockrell AS, Ma H, McCown T, Kluckman KD, Thresher RJ, Kafri T. 478. A HIV-1 Based Cross-Packaging System for FIV Vectors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.018 |
0.391 |
|
2004 |
McCown TJ. The clinical potential of antiepileptic gene therapy. Expert Opinion On Biological Therapy. 4: 1771-6. PMID 15500405 DOI: 10.1517/14712598.4.11.1771 |
0.426 |
|
2004 |
Haack K, Cockrell AS, Ma H, Israeli D, Ho SN, McCown TJ, Kafri T. Transactivator and structurally optimized inducible lentiviral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 585-96. PMID 15336658 DOI: 10.1016/J.Ymthe.2004.06.109 |
0.418 |
|
2004 |
Cockrell AS, Fu K, Ma H, McCown T, Kafri T. 69. Closing-in on the titer gap between transient transfection and packaging cell lines Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.004 |
0.416 |
|
2003 |
Haberman RP, Samulski RJ, McCown TJ. Attenuation of seizures and neuronal death by adeno-associated virus vector galanin expression and secretion. Nature Medicine. 9: 1076-80. PMID 12858168 DOI: 10.1038/nm901 |
0.455 |
|
2002 |
Haberman RP, McCown TJ. Regulation of gene expression in adeno-associated virus vectors in the brain. Methods (San Diego, Calif.). 28: 219-26. PMID 12413420 DOI: 10.1016/S1046-2023(02)00226-8 |
0.445 |
|
2002 |
Haberman R, Criswell H, Snowdy S, Ming Z, Breese G, Samulski R, McCown T. Therapeutic liabilities of in vivo viral vector tropism: adeno-associated virus vectors, NMDAR1 antisense, and focal seizure sensitivity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 495-500. PMID 12377191 DOI: 10.1006/Mthe.2002.0701 |
0.758 |
|
2002 |
Fu H, Samulski RJ, McCown TJ, Picornell YJ, Fletcher D, Muenzer J. Neurological correction of lysosomal storage in a mucopolysaccharidosis IIIB mouse model by adeno-associated virus-mediated gene delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 42-9. PMID 11786044 DOI: 10.1006/Mthe.2001.0514 |
0.408 |
|
2001 |
Xu K, Ma H, McCown TJ, Verma IM, Kafri T. Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 97-104. PMID 11162316 DOI: 10.1006/Mthe.2000.0238 |
0.364 |
|
2000 |
Haberman RP, McCown TJ, Samulski RJ. Novel transcriptional regulatory signals in the adeno-associated virus terminal repeat A/D junction element. Journal of Virology. 74: 8732-9. PMID 10954575 DOI: 10.1128/Jvi.74.18.8732-8739.2000 |
0.471 |
|
1998 |
Haberman RP, McCown TJ, Samulski RJ. Inducible long-term gene expression in brain with adeno-associated virus gene transfer. Gene Therapy. 5: 1604-11. PMID 10023439 DOI: 10.1038/Sj.Gt.3300782 |
0.564 |
|
1998 |
Bartlett JS, Samulski RJ, McCown TJ. Selective and rapid uptake of adeno-associated virus type 2 in brain. Human Gene Therapy. 9: 1181-6. PMID 9625257 DOI: 10.1089/hum.1998.9.8-1181 |
0.379 |
|
1997 |
Xiao X, McCown TJ, Li J, Breese GR, Morrow AL, Samulski RJ. Adeno-associated virus (AAV) vector antisense gene transfer in vivo decreases GABA(A) alpha1 containing receptors and increases inferior collicular seizure sensitivity. Brain Research. 756: 76-83. PMID 9187316 DOI: 10.1016/S0006-8993(97)00120-0 |
0.376 |
|
1997 |
Xiao X, Li J, McCown TJ, Samulski RJ. Gene transfer by adeno-associated virus vectors into the central nervous system. Experimental Neurology. 144: 113-24. PMID 9126160 DOI: 10.1006/Exnr.1996.6396 |
0.433 |
|
1997 |
Samulski RJ, During MJ, Kaplitt MG, Xiao X, Redman G, McCown T. Adeno-associated virus vectors yield long-term expression and delivery of potentially therapeutic genes into non-dividing neuronal cells Journal of Neurovirology. 3: S72. |
0.445 |
|
1996 |
McCown TJ, Xiao X, Li J, Breese GR, Samulski RJ. Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector. Brain Research. 713: 99-107. PMID 8724980 DOI: 10.1016/0006-8993(95)01488-8 |
0.454 |
|
Show low-probability matches. |