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Gwendalyn DiAnn King, Ph.D. - Publications

Affiliations: 
Neurobiology University of Alabama, Birmingham, Birmingham, AL, United States 
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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Vo HT, Phillips ML, Herskowitz JH, King GD. Klotho deficiency affects the spine morphology and network synchronization of neurons. Molecular and Cellular Neurosciences. PMID 30991103 DOI: 10.1016/J.Mcn.2019.04.002  0.347
2019 Laszczyk AM, Nettles D, Pollock TA, Fox S, Garcia ML, Wang J, Quarles LD, King GD. FGF-23 Deficiency Impairs Hippocampal-Dependent Cognitive Function. Eneuro. 6. PMID 30911673 DOI: 10.1523/ENEURO.0469-18.2019  0.743
2017 Han X, Ross J, Kolumam G, Pi M, Sonoda J, King G, Quarles LD. Cardiovascular Effects of Renal Distal Tubule Deletion of the FGF Receptor 1 Gene. Journal of the American Society of Nephrology : Jasn. PMID 28993502 DOI: 10.1681/Asn.2017040412  0.311
2017 Laszczyk AM, Fox-Quick S, Vo HT, Nettles D, Pugh PC, Overstreet-Wadiche L, King GD. Klotho regulates postnatal neurogenesis and protects against age-related spatial memory loss. Neurobiology of Aging. 59: 41-54. PMID 28837861 DOI: 10.1016/J.Neurobiolaging.2017.07.008  0.705
2017 Li Q, Vo HT, Wang J, Fox-Quick S, Dobrunz LE, King GD. Klotho regulates CA1 hippocampal synaptic plasticity. Neuroscience. PMID 28215989 DOI: 10.1016/J.Neuroscience.2017.02.006  0.301
2015 Vaden JH, Bhattacharyya BJ, Chen PC, Watson JA, Marshall AG, Phillips SE, Wilson JA, King GD, Miller RJ, Wilson SM. Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junction. Molecular Neurodegeneration. 10: 3. PMID 25575639 DOI: 10.1186/1750-1326-10-3  0.337
2014 Mehi SJ, Maltare A, Abraham CR, King GD. MicroRNA-339 and microRNA-556 regulate Klotho expression in vitro. Age (Dordrecht, Netherlands). 36: 141-9. PMID 23818104 DOI: 10.1007/S11357-013-9555-6  0.591
2013 Tucker Zhou TB, King GD, Chen C, Abraham CR. Biochemical and functional characterization of the klotho-VS polymorphism implicated in aging and disease risk. The Journal of Biological Chemistry. 288: 36302-11. PMID 24217253 DOI: 10.1074/Jbc.M113.490052  0.705
2013 Reish NJ, Maltare A, McKeown AS, Laszczyk AM, Kraft TW, Gross AK, King GD. The age-regulating protein klotho is vital to sustain retinal function. Investigative Ophthalmology & Visual Science. 54: 6675-85. PMID 24045987 DOI: 10.1167/Iovs.13-12550  0.341
2013 Clinton SM, Glover ME, Maltare A, Laszczyk AM, Mehi SJ, Simmons RK, King GD. Expression of klotho mRNA and protein in rat brain parenchyma from early postnatal development into adulthood. Brain Research. 1527: 1-14. PMID 23838326 DOI: 10.1016/J.Brainres.2013.06.044  0.348
2012 Candolfi M, King GD, Yagiz K, Curtin JF, Mineharu Y, Muhammad AK, Foulad D, Kroeger KM, Barnett N, Josien R, Lowenstein PR, Castro MG. Plasmacytoid dendritic cells in the tumor microenvironment: immune targets for glioma therapeutics. Neoplasia (New York, N.Y.). 14: 757-70. PMID 22952428 DOI: 10.1593/Neo.12794  0.64
2012 So PP, Zeldich E, Seyb KI, Huang MM, Concannon JB, King GD, Chen CD, Cuny GD, Glicksman MA, Abraham CR. Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerization. American Journal of Neurodegenerative Disease. 1: 75-87. PMID 22822474  0.728
2012 King GD, Chen C, Huang MM, Zeldich E, Brazee PL, Schuman ER, Robin M, Cuny GD, Glicksman MA, Abraham CR. Identification of novel small molecules that elevate Klotho expression. The Biochemical Journal. 441: 453-61. PMID 21939436 DOI: 10.1042/Bj20101909  0.753
2012 King GD, Rosene DL, Abraham CR. Promoter methylation and age-related downregulation of Klotho in rhesus monkey. Age (Dordrecht, Netherlands). 34: 1405-19. PMID 21922250 DOI: 10.1007/S11357-011-9315-4  0.576
2011 King GD, Muhammad AG, Larocque D, Kelson KR, Xiong W, Liu C, Sanderson NS, Kroeger KM, Castro MG, Lowenstein PR. Combined Flt3L/TK Gene Therapy Induces Immunological Surveillance Which Mediates an Immune Response Against a Surrogate Brain Tumor Neoantigen. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1793-1801. PMID 28160649 DOI: 10.1038/mt.2011.77  0.606
2011 Mineharu Y, King GD, Muhammad AK, Bannykh S, Kroeger KM, Liu C, Lowenstein PR, Castro MG. Engineering the brain tumor microenvironment enhances the efficacy of dendritic cell vaccination: implications for clinical trial design. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4705-18. PMID 21632862 DOI: 10.1158/1078-0432.Ccr-11-0915  0.629
2011 King GD, Muhammad AK, Larocque D, Kelson KR, Xiong W, Liu C, Sanderson NS, Kroeger KM, Castro MG, Lowenstein PR. Combined Flt3L/TK gene therapy induces immunological surveillance which mediates an immune response against a surrogate brain tumor neoantigen. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1793-801. PMID 21505426 DOI: 10.1038/Mt.2011.77  0.64
2011 Castro MG, Candolfi M, Kroeger K, King GD, Curtin JF, Yagiz K, Mineharu Y, Assi H, Wibowo M, Ghulam Muhammad AK, Foulad D, Puntel M, Lowenstein PR. Gene therapy and targeted toxins for glioma. Current Gene Therapy. 11: 155-80. PMID 21453286  0.579
2011 Candolfi M, Yagiz K, Balasubramanian K, Puntel M, King GD, Mineharu Y, Muhammad AG, Foulad D, Barnett N, Kroeger KM, Lowenstein PR, Castro MG. Abstract 467: Circulating DNA released from brain tumors in response to conditional cytotoxic/immune stimulatory gene therapy induces activation of TLR9 on pDCs, leading to antitumor immunity Cancer Research. 71: 467-467. DOI: 10.1158/1538-7445.Am2011-467  0.634
2010 Lowenstein PR, Mineharu Y, King G, Candolfi M, Xiong W, Assi H, Yagiz K, Kroeger K, Bannykh S, Castro M. Comparison of intratumoral loading of Flt3L/TK-recruited dendritic cells and systemic vaccination with tumor-lysate loaded dendritic cells in the stringent syngeneic CNS1 rat glioma model: Effect of temozolomide on anti-glioma immunity. Journal of Clinical Oncology. 28: 2093-2093. DOI: 10.1200/Jco.2010.28.15_Suppl.2093  0.625
2010 Abraham CR, Chen C, King GD. P3-469: Development of Klotho enhancers as novel therapeutics for Alzheimer's disease Alzheimer's & Dementia. 6: S591-S591. DOI: 10.1016/J.Jalz.2010.05.2012  0.741
2009 Ghulam Muhammad AK, Candolfi M, King GD, Yagiz K, Foulad D, Mineharu Y, Kroeger KM, Treuer KA, Nichols WS, Sanderson NS, Yang J, Khayznikov M, Van Rooijen N, Lowenstein PR, Castro MG. Antiglioma immunological memory in response to conditional cytotoxic/immune-stimulatory gene therapy: humoral and cellular immunity lead to tumor regression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6113-27. PMID 19789315 DOI: 10.1158/1078-0432.Ccr-09-1087  0.64
2009 Candolfi M, Yagiz K, Foulad D, Alzadeh GE, Tesarfreund M, Muhammad AK, Puntel M, Kroeger KM, Liu C, Lee S, Curtin JF, King GD, Lerner J, Sato K, Mineharu Y, et al. Release of HMGB1 in response to proapoptotic glioma killing strategies: efficacy and neurotoxicity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4401-14. PMID 19570774 DOI: 10.1158/1078-0432.Ccr-09-0155  0.614
2008 King GD, Kroeger KM, Bresee CJ, Candolfi M, Liu C, Manalo CM, Muhammad AG, Pechnick RN, Lowenstein PR, Castro MG. Flt3L in Combination With HSV1-TK-mediated Gene Therapy Reverses Brain Tumor-induced Behavioral Deficits. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 682-690. PMID 28178463 DOI: 10.1038/Mt.2008.18  0.649
2008 King GD, Muhammad AK, Xiong W, Kroeger KM, Puntel M, Larocque D, Palmer D, Ng P, Lowenstein PR, Castro MG. High-capacity adenovirus vector-mediated anti-glioma gene therapy in the presence of systemic antiadenovirus immunity. Journal of Virology. 82: 4680-4. PMID 18287240 DOI: 10.1128/Jvi.00232-08  0.644
2008 King GD, Kroeger KM, Bresee CJ, Candolfi M, Liu C, Manalo CM, Muhammad AK, Pechnick RN, Lowenstein PR, Castro MG. Flt3L in combination with HSV1-TK-mediated gene therapy reverses brain tumor-induced behavioral deficits. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 682-90. PMID 18283279 DOI: 10.1038/mt.2008.18  0.617
2008 King GD, Muhammad AK, Curtin JF, Barcia C, Puntel M, Liu C, Honig SB, Candolfi M, Mondkar S, Lowenstein PR, Castro MG. Flt3L and TK gene therapy eradicate multifocal glioma in a syngeneic glioblastoma model. Neuro-Oncology. 10: 19-31. PMID 18079358 DOI: 10.1215/15228517-2007-045  0.622
2008 King GD, Muhammad AKMG, Xiong W, Kroeger KM, Puntel M, Larocque D, Palmer D, Ng P, Lowenstein PR, Castro MG. High-capacity adenovirus vector-mediated anti-glioma gene therapy in the presence of systemic antiadenovirus immunity (Journal of Virology (2008) 82, 9, (4680-4684)) Journal of Virology. 82: 6087. DOI: 10.1128/Jvi.00828-08  0.595
2008 Abraham CR, Podvin S, King G, McKee A, Carreras I, Dedeoglu A, Chen C. O1-03-07: Klotho, aging and Alzheimer's Alzheimer's & Dementia. 4: T113-T114. DOI: 10.1016/J.Jalz.2008.05.235  0.738
2008 King GD, Chen C, Podvin S, Abraham CR. P4-186: Modulating Klotho expression to protect against age-induced neurodegeneration Alzheimer's & Dementia. 4: T725-T726. DOI: 10.1016/J.Jalz.2008.05.2253  0.75
2007 Barcia C, Jimenez-Dalmaroni M, Kroeger KM, Puntel M, Rapaport AJ, Larocque D, King GD, Johnson SA, Liu C, Xiong W, Candolfi M, Mondkar S, Ng P, Palmer D, Castro MG, et al. One-year expression from high-capacity adenoviral vectors in the brains of animals with pre-existing anti-adenoviral immunity: clinical implications. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 2154-63. PMID 17895861 DOI: 10.1038/Sj.Mt.6300305  0.647
2007 Candolfi M, Curtin JF, Nichols WS, Muhammad AG, King GD, Pluhar GE, McNiel EA, Ohlfest JR, Freese AB, Moore PF, Lerner J, Lowenstein PR, Castro MG. Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression. Journal of Neuro-Oncology. 85: 133-48. PMID 17874037 DOI: 10.1007/S11060-007-9400-9  0.625
2006 Barcia C, Thomas CE, Curtin JF, King GD, Wawrowsky K, Candolfi M, Xiong WD, Liu C, Kroeger K, Boyer O, Kupiec-Weglinski J, Klatzmann D, Castro MG, Lowenstein PR. In vivo mature immunological synapses forming SMACs mediate clearance of virally infected astrocytes from the brain. The Journal of Experimental Medicine. 203: 2095-107. PMID 16923851 DOI: 10.1084/Jem.20060420  0.597
2006 Curtin JF, King GD, Barcia C, Liu C, Hubert FX, Guillonneau C, Josien R, Anegon I, Lowenstein PR, Castro MG. Fms-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain. Journal of Immunology (Baltimore, Md. : 1950). 176: 3566-77. PMID 16517725 DOI: 10.4049/Jimmunol.176.6.3566  0.612
2006 Xiong W, Goverdhana S, Sciascia SA, Candolfi M, Zirger JM, Barcia C, Curtin JF, King GD, Jaita G, Liu C, Kroeger K, Agadjanian H, Medina-Kauwe L, Palmer D, Ng P, et al. Regulatable gutless adenovirus vectors sustain inducible transgene expression in the brain in the presence of an immune response against adenoviruses. Journal of Virology. 80: 27-37. PMID 16352528 DOI: 10.1128/Jvi.80.1.27-37.2006  0.64
2006 King GD, Curtin JF, Liu C, Bresee C, Honig SB, Zirger JM, VanRooijen N, Ribas A, Pechnick R, Lowenstein PR, Castro MG. 621. Immunological Memory in a Syngeneic Model of Recurrent and Multifocal Glioblastoma Molecular Therapy. 13: S239. DOI: 10.1016/J.Ymthe.2006.08.696  0.639
2006 Curtin JF, King GD, Candolfi M, Liu C, Michelsen KS, Arditi M, Fakhouri TM, Comin-Anduix B, Ribas A, Lowenstein PR, Castro MG. 424. Myd88/TLR Signaling Is Required for Immunotherapy-Mediated Glioblastoma Regression Molecular Therapy. 13: S163. DOI: 10.1016/J.Ymthe.2006.08.489  0.63
2006 Barcia C, Thomas C, Curtin JF, King GD, Wawrowsky K, Candolfi M, Xiong W, Chunyan L, Kroeger K, Boyer O, Kupiec-Weglinski J, Klatzmann D, Castro MG, Lowenstein PR. 999. Mature Effector Immunological Synapses Forming SMAC Mediate Clearance of Virally Infected Astrocytes from the Brain In Vivo Molecular Therapy. 13: S385. DOI: 10.1016/J.Ymthe.2006.08.1092  0.591
2005 King GD, Curtin JF, Candolfi M, Kroeger K, Lowenstein PR, Castro MG. Gene therapy and targeted toxins for glioma. Current Gene Therapy. 5: 535-57. PMID 16457645 DOI: 10.2174/156652305774964631  0.615
2005 Curtin JF, King GD, Candolfi M, Greeno RB, Kroeger KM, Lowenstein PR, Castro MG. Combining cytotoxic and immune-mediated gene therapy to treat brain tumors. Current Topics in Medicinal Chemistry. 5: 1151-70. PMID 16248789 DOI: 10.2174/156802605774370856  0.632
2005 Ali S, King GD, Curtin JF, Candolfi M, Xiong W, Liu C, Puntel M, Cheng Q, Prieto J, Ribas A, Kupiec-Weglinski J, van Rooijen N, Lassmann H, Lowenstein PR, Castro MG. Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model. Cancer Research. 65: 7194-204. PMID 16103070 DOI: 10.1158/0008-5472.Can-04-3434  0.617
2005 Goverdhana S, Puntel M, Xiong W, Zirger JM, Barcia C, Curtin JF, Soffer EB, Mondkar S, King GD, Hu J, Sciascia SA, Candolfi M, Greengold DS, Lowenstein PR, Castro MG. Regulatable gene expression systems for gene therapy applications: progress and future challenges. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 189-211. PMID 15946903 DOI: 10.1016/J.Ymthe.2005.03.022  0.606
2005 Curtin JF, King GD, Xiong W, Liu C, Lowenstein P, Castro M. 269. Stimulation of the Immune System Using Gene Therapy Is an Effective Approach for Treating Brain Tumors in Mouse and Rat Models Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.272  0.406
2005 Xiong W, Goverdhana S, Curtin JF, Barcia-Gonzalez C, Zirger JM, King GD, Sciascia SA, Puntel M, Candolfi M, Palmer D, Ng P, Lowenstein PR, Castro MG. 143. Regulated, High Capacity Adenoviral Vectors Mediated Long-Term Gene Expression in the Brain Even in the Presence of a Peripheral Immune Response to Adenovirus Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.148  0.629
2004 Ali S, Curtin JF, Zirger JM, Xiong W, King GD, Barcia C, Liu C, Puntel M, Goverdhana S, Lowenstein PR, Castro MG. Inflammatory and anti-glioma effects of an adenovirus expressing human soluble Fms-like tyrosine kinase 3 ligand (hsFlt3L): treatment with hsFlt3L inhibits intracranial glioma progression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 1071-84. PMID 15564139 DOI: 10.1016/J.Ymthe.2004.08.025  0.649
2004 King GD, Cherian K, Turner RS. X11alpha impairs gamma- but not beta-cleavage of amyloid precursor protein. Journal of Neurochemistry. 88: 971-82. PMID 14756819 DOI: 10.1046/J.1471-4159.2003.02234.X  0.533
2004 King GD, Scott Turner R. Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk? Experimental Neurology. 185: 208-19. PMID 14736502 DOI: 10.1016/J.Expneurol.2003.10.011  0.327
2003 King GD, Perez RG, Steinhilb ML, Gaut JR, Turner RS. X11alpha modulates secretory and endocytic trafficking and metabolism of amyloid precursor protein: mutational analysis of the YENPTY sequence. Neuroscience. 120: 143-54. PMID 12849748 DOI: 10.1016/S0306-4522(03)00284-7  0.527
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