Richard H. Ashley - Publications

RETIRED University of Edinburgh, Edinburgh, Scotland, United Kingdom 
Ion Channels

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Spiekerkoetter E, Guignabert C, de Jesus Perez V, Alastalo TP, Powers JM, Wang L, Lawrie A, Ambartsumian N, Schmidt AM, Berryman M, Ashley RH, Rabinovitch M. S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4. Circulation Research. 105: 639-47, 13 p followi. PMID 19713532 DOI: 10.1161/CIRCRESAHA.109.205120  1
2007 Singh H, Cousin MA, Ashley RH. Functional reconstitution of mammalian 'chloride intracellular channels' CLIC1, CLIC4 and CLIC5 reveals differential regulation by cytoskeletal actin. The Febs Journal. 274: 6306-16. PMID 18028448 DOI: 10.1111/j.1742-4658.2007.06145.x  1
2007 Singh H, Ashley RH. CLIC4 (p64H1) and its putative transmembrane domain form poorly selective, redox-regulated ion channels. Molecular Membrane Biology. 24: 41-52. PMID 17453412 DOI: 10.1080/09687860600927907  1
2006 Ashley RH, Harroun TA, Hauss T, Breen KC, Bradshaw JP. Autoinsertion of soluble oligomers of Alzheimer's Abeta(1-42) peptide into cholesterol-containing membranes is accompanied by relocation of the sterol towards the bilayer surface. Bmc Structural Biology. 6: 21. PMID 17052343 DOI: 10.1186/1472-6807-6-21  1
2006 Singh H, Ashley RH. Redox regulation of CLIC1 by cysteine residues associated with the putative channel pore. Biophysical Journal. 90: 1628-38. PMID 16339885 DOI: 10.1529/biophysj.105.072678  1
2005 Suzuki Y, Yuen SR, Ashley R. Short, thin asbestos fibers contribute to the development of human malignant mesothelioma: Pathological evidence International Journal of Hygiene and Environmental Health. 208: 201-210. PMID 15971859 DOI: 10.1016/j.ijheh.2005.01.015  1
2005 Balali-Mood K, Ashley RH, Hauss T, Bradshaw JP. Neutron diffraction reveals sequence-specific membrane insertion of pre-fibrillar islet amyloid polypeptide and inhibition by rifampicin. Febs Letters. 579: 1143-8. PMID 15710403 DOI: 10.1016/j.febslet.2004.12.085  1
2005 Findlay HE, McClafferty H, Ashley RH. Surface expression, single-channel analysis and membrane topology of recombinant Chlamydia trachomatis Major Outer Membrane Protein. Bmc Microbiology. 5: 5. PMID 15673471 DOI: 10.1186/1471-2180-5-5  1
2004 Siritapetawee J, Prinz H, Samosornsuk W, Ashley RH, Suginta W. Functional reconstitution, gene isolation and topology modelling of porins from Burkholderia pseudomallei and Burkholderia thailandensis. The Biochemical Journal. 377: 579-87. PMID 14567756 DOI: 10.1042/BJ20031118  1
2003 Shorning BY, Wilson DB, Meehan RR, Ashley RH. Molecular cloning and developmental expression of two Chloride Intracellular Channel (CLIC) genes in Xenopus laevis. Development Genes and Evolution. 213: 514-8. PMID 13680226 DOI: 10.1007/s00427-003-0356-2  1
2003 Ashley RH. Challenging accepted ion channel biology: p64 and the CLIC family of putative intracellular anion channel proteins (Review). Molecular Membrane Biology. 20: 1-11. PMID 12745921 DOI: 10.1080/0968768021000042746  1
2002 Proutski I, Karoulias N, Ashley RH. Overexpressed chloride intracellular channel protein CLIC4 (p64H1) is an essential component of novel plasma membrane anion channels. Biochemical and Biophysical Research Communications. 297: 317-22. PMID 12237120 DOI: 10.1016/S0006-291X(02)02199-X  1
2001 Harroun TA, Bradshaw JP, Ashley RH. Inhibitors can arrest the membrane activity of human islet amyloid polypeptide independently of amyloid formation. Febs Letters. 507: 200-4. PMID 11684098 DOI: 10.1016/S0014-5793(01)02972-6  1
2001 Hardy SP, Ritchie C, Allen MC, Ashley RH, Granum PE. Clostridium perfringens type A enterotoxin forms mepacrine-sensitive pores in pure phospholipid bilayers in the absence of putative receptor proteins. Biochimica Et Biophysica Acta. 1515: 38-43. PMID 11597350 DOI: 10.1016/S0005-2736(01)00391-1  1
2001 Suginta W, Karoulias N, Aitken A, Ashley RH. Chloride intracellular channel protein CLIC4 (p64H1) binds directly to brain dynamin I in a complex containing actin, tubulin and 14-3-3 isoforms. The Biochemical Journal. 359: 55-64. PMID 11563969 DOI: 10.1042/0264-6021:3590055  1
2001 Hughes ES, Shaw KM, Ashley RH. Mutagenesis and functional reconstitution of chlamydial major outer membrane proteins: VS4 domains are not required for pore formation but modify channel function. Infection and Immunity. 69: 1671-8. PMID 11179342 DOI: 10.1128/IAI.69.3.1671-1678.2001  1
2000 Volynski KE, Meunier FA, Lelianova VG, Dudina EE, Volkova TM, Rahman MA, Manser C, Grishin EV, Dolly JO, Ashley RH, Ushkaryov YA. Latrophilin, neurexin, and their signaling-deficient mutants facilitate alpha -latrotoxin insertion into membranes but are not involved in pore formation. The Journal of Biological Chemistry. 275: 41175-83. PMID 11024019 DOI: 10.1074/jbc.M005857200  1
2000 Niu TK, Ashley RH. Expression of full-length and truncated recombinant human brain type I inositol 1,4,5-trisphosphate receptors in mammalian and insect cells. Biochemical and Biophysical Research Communications. 273: 123-8. PMID 10917868 DOI: 10.1006/bbrc.2000.2884  1
1999 Martin C, Hyvelin JM, Chapman KE, Marthan R, Ashley RH, Savineau JP. Pregnant rat myometrial cells show heterogeneous ryanodine- and caffeine-sensitive calcium stores. American Journal of Physiology. Cell Physiology. 277: C243-C252. PMID 29590838 DOI: 10.1152/ajpcell.1999.277.2.C243  1
1999 Martin C, Chapman KE, Thornton S, Ashley RH. Changes in the expression of myometrial ryanodine receptor mRNAs during human pregnancy. Biochimica Et Biophysica Acta. 1451: 343-52. PMID 10556588 DOI: 10.1016/S0167-4889(99)00104-4  1
1999 Martin C, Hyvelin JM, Chapman KE, Marthan R, Ashley RH, Savineau JP. Pregnant rat myometrial cells show heterogeneous ryanodine- and caffeine-sensitive calcium stores. The American Journal of Physiology. 277: C243-52. PMID 10444400  1
1999 Hadad N, Martin C, Ashley RH, Shoshan-Barmatz V. Characterization of sheep brain ryanodine receptor ATP binding site by photoaffinity labeling. Febs Letters. 455: 251-6. PMID 10437783 DOI: 10.1016/S0014-5793(99)00738-3  1
1999 Janson J, Ashley RH, Harrison D, McIntyre S, Butler PC. The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles. Diabetes. 48: 491-8. PMID 10078548  1
1999 Wyllie S, Longbottom D, Herring AJ, Ashley RH. Single channel analysis of recombinant major outer membrane protein porins from Chlamydia psittaci and Chlamydia pneumoniae. Febs Letters. 445: 192-6. PMID 10069399 DOI: 10.1016/S0014-5793(99)00121-0  1
1998 Wyllie S, Ashley RH, Longbottom D, Herring AJ. The major outer membrane protein of Chlamydia psittaci functions as a porin-like ion channel. Infection and Immunity. 66: 5202-7. PMID 9784523  1
1998 Shoshan-Barmatz V, Ashley RH. The structure, function, and cellular regulation of ryanodine-sensitive Ca2+ release channels. International Review of Cytology. 183: 185-270. PMID 9666568  1
1998 Martin C, Chapman KE, Seckl JR, Ashley RH. Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum. Neuroscience. 85: 205-16. PMID 9607712 DOI: 10.1016/S0306-4522(97)00612-X  1
1997 Duncan RR, Westwood PK, Boyd A, Ashley RH. Rat brain p64H1, expression of a new member of the p64 chloride channel protein family in endoplasmic reticulum. The Journal of Biological Chemistry. 272: 23880-6. PMID 9295337 DOI: 10.1074/jbc.272.38.23880  1
1997 Clark AG, Murray D, Ashley RH. Single-channel properties of a rat brain endoplasmic reticulum anion channel. Biophysical Journal. 73: 168-78. PMID 9199781 DOI: 10.1016/S0006-3495(97)78057-3  1
1996 Howell S, Duncan RR, Ashley RH. Identification and characterisation of a homologue of p64 in rat tissues. Febs Letters. 390: 207-10. PMID 8706861 DOI: 10.1016/0014-5793(96)00676-X  1
1995 Ashley RH. Intracellular calcium channels. Essays in Biochemistry. 30: 97-117. PMID 8822151  1
1995 Suzuki Y, Weston A, Ashley R. Immunocytochemical analysis of oncoproteins and growth factors in human malignant mesothelioma Oncology Reports. 2: 897-902.  1
1994 Silvestro AM, Ashley RH. Solubilization, partial purification and functional reconstitution of a sheep brain endoplasmic reticulum anion channel. The International Journal of Biochemistry. 26: 1129-38. PMID 7988737 DOI: 10.1016/0020-711X(94)90135-X  1
1994 Silvestro AM, Ashley R. Functional reconstitution of the transport activity of a partially purified brain anion channel Biochemical Society Transactions. 22: 221S. PMID 7958283  1
1994 Ashley RH, Brown DM, Apps DK, Phillips JH. Evidence for a K+ channel in bovine chromaffin granule membranes: single-channel properties and possible bioenergetic significance. European Biophysics Journal : Ebj. 23: 263-75. PMID 7528657 DOI: 10.1007/BF00213576  1
1993 Martin C, Ashley R, Shoshan-Barmatz V. The effect of local anaesthetics on the ryanodine receptor/Ca2+ release channel of brain microsomal membranes Febs Letters. 328: 77-81. PMID 8393810 DOI: 10.1016/0014-5793(93)80969-2  1
1993 Orr I, Martin C, Ashley R, Shoshan-Barmatz V. The interaction of fluorescein isothiocyanate with the ryanodine receptor/Ca2+ release channel of sarcoplasmic reticulum Journal of Biological Chemistry. 268: 1376-1382. PMID 8380411  1
1993 Martin C, Ashley RH. Reconstitution of a voltage-activated calcium conducting cation channel from brain microsomes. Cell Calcium. 14: 427-38. PMID 7689423 DOI: 10.1016/0143-4160(93)90002-N  1
1993 Hayman KA, Ashley RH. Structural features of a multisubstate cardiac mitoplast anion channel: inferences from single channel recording. The Journal of Membrane Biology. 136: 191-7. PMID 7508982 DOI: 10.1007/BF02505763  1
1993 Hayman KA, Spurway TD, Ashley RH. Single anion channels reconstituted from cardiac mitoplasts. The Journal of Membrane Biology. 136: 181-90. PMID 7508981 DOI: 10.1007/BF02505762  1
1992 Duff KC, Ashley RH. The transmembrane domain of influenza A M2 protein forms amantadine-sensitive proton channels in planar lipid bilayers. Virology. 190: 485-9. PMID 1382343 DOI: 10.1016/0042-6822(92)91239-Q  1
1991 Murray D, Ashley R. An intracellular anion channel from rat brain microsomes which is also permeable to cations Biochemical Society Transactions. 19: 255S. PMID 1723699  1
1991 Spurway TD, Ashley R. Evidence for a pH-dependent anion channel in sheep heart mitochondria Biochemical Society Transactions. 19: 254S. PMID 1723698  1
1990 Ashley RH, Williams AJ. Divalent cation activation and inhibition of single calcium release channels from sheep cardiac sarcoplasmic reticulum. The Journal of General Physiology. 95: 981-1005. PMID 2163436 DOI: 10.1085/jgp.95.5.981  1
1989 Ashley RH. Brain microsomes bind ryanodine and contain ryanodine-sensitive calcium channels. Biochemical Society Transactions. 17: 1102-3. PMID 2560738  1
1989 Ashley RH. Activation and conductance properties of ryanodine-sensitive calcium channels from brain microsomal membranes incorporated into planar lipid bilayers. The Journal of Membrane Biology. 111: 179-89. PMID 2559202 DOI: 10.1007/BF01871781  1
1989 Williams AJ, Ashley RH. Reconstitution of cardiac sarcoplasmic reticulum calcium channels. Annals of the New York Academy of Sciences. 560: 163-73. PMID 2545131  1
1987 Adam-Vizi V, Ashley RH. Relation of acetylcholine release to Ca2+ uptake and intraterminal Ca2+ concentration in guinea-pig cortex synaptosomes. Journal of Neurochemistry. 49: 1013-21. PMID 3625199  1
1986 Ashley RH. Buffer capacity of intracellular Ca2+ indicators. The Biochemical Journal. 240: 310-1. PMID 3827852  1
1986 Ashley RH. External calcium, intrasynaptosomal free calcium and neurotransmitter release. Biochimica Et Biophysica Acta. 854: 207-12. PMID 2867783 DOI: 10.1016/0005-2736(86)90112-4  1
1984 Ashley RH, Brammer MJ. A fluorescence polarization study of calcium and phase behaviour in synaptosomal lipids. Biochimica Et Biophysica Acta. 769: 363-9. PMID 6696888 DOI: 10.1016/0005-2736(84)90318-3  1
1984 Ashley RH, Brammer MJ, Marchbanks R. Measurement of intrasynaptosomal free calcium by using the fluorescent indicator quin-2. The Biochemical Journal. 219: 149-58. PMID 6326754  1
1984 Ashley RH, Brammer MJ, Marchbanks RM. Fluorescence measurements of intrasynaptosomal free calcium by using a Quin dye Biochemical Society Transactions. 12: 869-870.  1
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