Malcolm B. Segal - Publications

Affiliations: 
King's College London, London, UK 
Area:
Blood Brain Barrier

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Chen RL, Kassem NA, Redzic ZB, Chen CP, Segal MB, Preston JE. Age-related changes in choroid plexus and blood-cerebrospinal fluid barrier function in the sheep. Experimental Gerontology. 44: 289-96. PMID 19133323 DOI: 10.1016/j.exger.2008.12.004  0.379
2008 Isakovic AJ, Dencic SM, Segal MB, Redzic ZB. Transport of [14C]hypoxanthine by sheep choroid plexus epithelium as a monolayer in primary culture: Na+-dependent and Na+-independent uptake by the apical membrane and rapid intracellular metabolic conversion to nucleotides. Neuroscience Letters. 431: 135-40. PMID 18164814 DOI: 10.1016/j.neulet.2007.11.029  0.372
2008 Markovic I, Segal M, Djuricic B, Redzic Z. Kinetics of nucleoside uptake by the basolateral side of the sheep choroid plexus epithelium perfused in situ. Experimental Physiology. 93: 325-33. PMID 18039975 DOI: 10.1113/expphysiol.2007.040980  0.377
2007 Kassem NA, Deane R, Segal MB, Chen R, Preston JE. Thyroxine (T4) transfer from CSF to choroid plexus and ventricular brain regions in rabbit: contributory role of P-glycoprotein and organic anion transporting polypeptides. Brain Research. 1181: 44-50. PMID 17915195 DOI: 10.1016/j.brainres.2007.08.052  0.396
2006 Kassem NA, Deane R, Segal MB, Preston JE. Role of transthyretin in thyroxine transfer from cerebrospinal fluid to brain and choroid plexus. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 291: R1310-5. PMID 16825415 DOI: 10.1152/ajpregu.00789.2005  0.438
2006 Redzic ZB, Isakovic AJ, Misirlic Dencic ST, Popadic D, Segal MB. Uneven distribution of nucleoside transporters and intracellular enzymatic degradation prevent transport of intact [14C] adenosine across the sheep choroid plexus epithelium as a monolayer in primary culture. Cerebrospinal Fluid Research. 3: 4. PMID 16571111 DOI: 10.1186/1743-8454-3-4  0.364
2005 Chen RL, Athauda SB, Kassem NA, Zhang Y, Segal MB, Preston JE. Decrease of transthyretin synthesis at the blood-cerebrospinal fluid barrier of old sheep. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 60: 852-8. PMID 16079207 DOI: 10.1093/Gerona/60.7.852  0.372
2005 Alexander B, Smart KA, Segal MB, Preston JE. Hyperammonaemia reduces intracellular 22Na (sodium) ion and extracellular 86Rb ion concentrations in the blood-brain barrier of the rat. Metabolic Brain Disease. 20: 19-33. PMID 15918547 DOI: 10.1007/s11011-005-2473-2  0.511
2004 Redzic ZB, Segal MB. The structure of the choroid plexus and the physiology of the choroid plexus epithelium. Advanced Drug Delivery Reviews. 56: 1695-716. PMID 15381330 DOI: 10.1016/j.addr.2004.07.005  0.356
2003 Zheng W, Deane R, Redzic Z, Preston JE, Segal MB. Transport of L-[125I]thyroxine by in situ perfused ovine choroid plexus: inhibition by lead exposure. Journal of Toxicology and Environmental Health. Part A. 66: 435-51. PMID 12712631 DOI: 10.1080/15287390306451  0.373
2002 Dacevic MP, Tasic JS, Pejanovic VM, Segal MB, Ugliesic-Kilibarda DD, Isakovic AJ, Begley DJ, Rakic LM, Redzic ZB. The linkage of glucose to tiazofurin decreases in vitro uptake into rat glioma C6 cells. Journal of Drug Targeting. 10: 633-6. PMID 12683668 DOI: 10.1080/1061186021000038030  0.363
2002 Monro OR, Mackic JB, Yamada S, Segal MB, Ghiso J, Maurer C, Calero M, Frangione B, Zlokovic BV. Substitution at codon 22 reduces clearance of Alzheimer's amyloid-beta peptide from the cerebrospinal fluid and prevents its transport from the central nervous system into blood. Neurobiology of Aging. 23: 405-12. PMID 11959403 DOI: 10.1016/S0197-4580(01)00317-7  0.381
2002 Isakovic AJ, Segal MB, Milojkovic BA, Dacevic MP, Misirlic ST, Rakic ML, Redzic ZB. The efflux of purine nucleobases and nucleosides from the rat brain. Neuroscience Letters. 318: 65-8. PMID 11796187 DOI: 10.1016/S0304-3940(01)02478-8  0.484
2002 Redzic ZB, Gasic JM, Segal MB, Markovic ID, Isakovic AJ, Rakic MLj, Thomas SA, Rakic LM. The kinetics of hypoxanthine transport across the perfused choroid plexus of the sheep. Brain Research. 925: 169-75. PMID 11792365 DOI: 10.1016/S0006-8993(01)03272-3  0.408
2001 Thomas SA, Bye A, Segal MB. Transport characteristics of the anti-human immunodeficiency virus nucleoside analog, abacavir, into brain and cerebrospinal fluid. The Journal of Pharmacology and Experimental Therapeutics. 298: 947-53. PMID 11504789  0.342
2001 Redzic ZB, Isakovic A, Segal MB, Thomas SA, Rakic LM. The kinetics of hypoxanthine efflux from the rat brain. Brain Research. 899: 248-50. PMID 11311886 DOI: 10.1016/S0006-8993(01)02115-1  0.375
2001 Thomas SA, Preston JE, Wilson MR, Farrell CL, Segal MB. Leptin transport at the blood--cerebrospinal fluid barrier using the perfused sheep choroid plexus model. Brain Research. 895: 283-90. PMID 11259792 DOI: 10.1016/S0006-8993(01)02116-3  0.552
2001 Redzic ZB, Segal MB, Gasic JM, Markovic ID, Vojvodic VP, Isakovic A, Thomas SA, Rakic LM. The characteristics of nucleobase transport and metabolism by the perfused sheep choroid plexus. Brain Research. 888: 66-74. PMID 11146053 DOI: 10.1016/S0006-8993(00)03006-7  0.428
2001 Segal MB. Transport of nutrients across the choroid plexus. Microscopy Research and Technique. 52: 38-48. PMID 11135447 DOI: 10.1002/1097-0029(20010101)52:1<38::AID-JEMT6>3.0.CO;2-J  0.402
2000 Thomas S, Cass L, Prince W, Segal M. Brain and CSF entry of the novel non-nucleoside reverse transcriptase inhibitor, GW420867X Neuroreport. 11: 3811-3815. PMID 11117496 DOI: 10.1097/00001756-200011270-00043  0.491
2000 Alexander B, Li X, Benjamin IS, Segal MB, Sherwood R, Preston JE. A quantitative evaluation of the permeability of the blood brain barrier of portacaval shunted rats. Metabolic Brain Disease. 15: 93-103. PMID 11092576 DOI: 10.1007/Bf02679976  0.505
2000 Redzic ZB, Segal MB, Gasic JM, Markovic ID, Isakovic A, Rakic LM. The kinetics of tiazofurin uptake by the isolated perfused choroid plexus of the sheep. Methods and Findings in Experimental and Clinical Pharmacology. 22: 149-54. PMID 10893696  0.405
2000 Segal MB. The choroid plexuses and the barriers between the blood and the cerebrospinal fluid. Cellular and Molecular Neurobiology. 20: 183-96. PMID 10696509 DOI: 10.1023/A:1007045605751  0.549
2000 Al-Sarraf H, Preston JE, Segal MB. Acidic amino acid clearance from CSF in the neonatal versus adult rat using ventriculo-cisternal perfusion. Journal of Neurochemistry. 74: 770-6. PMID 10646529 DOI: 10.1046/j.1471-4159.2000.740770.x  0.45
1998 Thomas SA, Segal MB. The transport of the anti-HIV drug, 2',3'-didehydro-3'-deoxythymidine (D4T), across the blood-brain and blood-cerebrospinal fluid barriers. British Journal of Pharmacology. 125: 49-54. PMID 9776343 DOI: 10.1038/sj.bjp.0702044  0.522
1998 Redzic ZB, Markovic ID, Vidovic VP, Vranic VP, Gasic JM, Duricic BM, Pokrajac M, Dordevic JB, Segal MB, Rakic LM. Endogenous nucleosides in the guinea-pig eye: analysis of transport and metabolites. Experimental Eye Research. 66: 315-25. PMID 9533859 DOI: 10.1006/exer.1997.0424  0.378
1997 Redzi? ZB, Segal MB, Markovi? ID, Gasi? JM, Vidovi? V, Raki? LM. The characteristics of basolateral nucleoside transport in the perfused sheep choroid plexus and the effect of nitric oxide inhibition on these processes. Brain Research. 767: 26-33. PMID 9365012 DOI: 10.1016/S0006-8993(97)00530-1  0.403
1997 al-Sarraf H, Preston JE, Segal MB. Changes in the kinetics of the acidic amino acid brain and CSF uptake during development in the rat. Brain Research. Developmental Brain Research. 102: 127-34. PMID 9298241 DOI: 10.1016/S0165-3806(97)00089-8  0.511
1997 al-Sarraf H, Preston JE, Segal MB. Acidic amino acid accumulation by rat choroid plexus during development. Brain Research. Developmental Brain Research. 102: 47-52. PMID 9298233 DOI: 10.1016/S0165-3806(97)00075-8  0.402
1997 Thomas SA, Segal MB. Saturation kinetics, specificity and NBMPR sensitivity of thymidine entry into the central nervous system. Brain Research. 760: 59-67. PMID 9237518 DOI: 10.1016/S0006-8993(97)00276-X  0.532
1997 Thomas SA, Segal MB. The passage of azidodeoxythymidine into and within the central nervous system: does it follow the parent compound, thymidine? The Journal of Pharmacology and Experimental Therapeutics. 281: 1211-8. PMID 9190855  0.407
1997 Thomas SA, Davson H, Segal MB. Quantification of efflux into the blood and brain of intraventricularly perfused [3H]thymidine in the anaesthetized rabbit. Experimental Physiology. 82: 139-48. PMID 9023512 DOI: 10.1113/Expphysiol.1997.Sp004003  0.689
1996 Thomas née Williams SA, Segal MB. Identification of a saturable uptake system for deoxyribonucleosides at the blood-brain and blood-cerebrospinal fluid barriers. Brain Research. 741: 230-9. PMID 9001727 DOI: 10.1016/S0006-8993(96)00930-4  0.581
1995 al-Sarraf H, Preston JE, Segal MB. The entry of acidic amino acids into brain and CSF during development, using in situ perfusion in the rat. Brain Research. Developmental Brain Research. 90: 151-8. PMID 8719338 DOI: 10.1016/0165-3806(96)83495-X  0.477
1995 Preston JE, al-Sarraf H, Segal MB. Permeability of the developing blood-brain barrier to 14C-mannitol using the rat in situ brain perfusion technique. Brain Research. Developmental Brain Research. 87: 69-76. PMID 7554234 DOI: 10.1016/0165-3806(95)00060-Q  0.488
1993 Segal MB. Extracellular and cerebrospinal fluids. Journal of Inherited Metabolic Disease. 16: 617-38. PMID 8412010 DOI: 10.1007/BF00711896  0.383
1993 Segal MB, Preston JE. The uptake of thyroxine by the isolated perfused choroid plexus of the sheep. Advances in Experimental Medicine and Biology. 331: 285-8. PMID 8333344 DOI: 10.1007/978-1-4615-2920-0_44  0.465
1993 Preston JE, Segal MB. Glycine transport into the anaesthetized developing rat brain and cerebrospinal fluid Journal of Physiology. 467: 129P.  0.374
1992 Preston JE, Segal MB. Saturable uptake of [125I]L-triiodothyronine at the basolateral (blood) and apical (cerebrospinal fluid) sides of the isolated perfused sheep choroid plexus. Brain Research. 592: 84-90. PMID 1450924 DOI: 10.1016/0006-8993(92)91661-W  0.407
1992 Preston JE, Segal MB. The uptake of anionic and cationic amino acids by the isolated perfused sheep choroid plexus. Brain Research. 581: 351-5. PMID 1393540 DOI: 10.1016/0006-8993(92)90731-N  0.309
1991 Somjen GG, Segal MB, Herreras O. Osmotic-hypertensive opening of the blood-brain barrier in rats does not necessarily provide access for potassium to cerebral interstitial fluid. Experimental Physiology. 76: 507-14. PMID 1910758 DOI: 10.1113/expphysiol.1991.sp003516  0.326
1991 Zlokovic BV, Segal MB, McComb JG, Hyman S, Weiss MH, Davson H. Kinetics of circulating vasopressin uptake by choroid plexus. The American Journal of Physiology. 260: F216-24. PMID 1899978 DOI: 10.1152/Ajprenal.1991.260.2.F216  0.547
1990 Segal MB, Preston JE, Zlokovic B. Comparison between blood and saline perfusion on the uptake of amino acids by choroid plexus of the sheep. Endocrinologia Experimentalis. 24: 29-36. PMID 2361466  0.306
1990 Schreiber G, Aldred AR, Jaworowski A, Nilsson C, Achen MG, Segal MB. Thyroxine transport from blood to brain via transthyretin synthesis in choroid plexus. The American Journal of Physiology. 258: R338-45. PMID 2309926  0.385
1990 Zlokovic BV, Segal MB, Davson H, Lipovac MN, Hyman S, McComb JG. Circulating neuroactive peptides and the blood-brain and blood-cerebrospinal fluid barriers. Endocrinologia Experimentalis. 24: 9-17. PMID 2193795  0.656
1990 Preston JE, Segal MB. The steady-state amino acid fluxes across the perfused choroid plexus of the sheep. Brain Research. 525: 275-9. PMID 2123729 DOI: 10.1016/0006-8993(90)90874-B  0.42
1990 Zlokovic BV, Skundric DS, Segal MB, Lipovac MN, Mackic JB, Davson H. A saturable mechanism for transport of immunoglobulin G across the blood-brain barrier of the guinea pig. Experimental Neurology. 107: 263-70. PMID 1689666 DOI: 10.1016/0014-4886(90)90144-H  0.667
1990 Zlokovic BV, Segal MB, Hyman S, McComb JG. Change in the blood-brain barrier during chronic amphetamine intoxication in the guinea-pig Fernstrom Foundation Series. 14: 291-294.  0.354
1990 Davson H, Lipovac MN, Mackic JB, Preston JE, Segal MB, Tang G, Zlokovic BV. Kinetics of L-glutamic acid uptake by the luminal side of the blood-brain barrier studied in an in situ perfused brain of the anaesthetized guinea-pig Journal of Physiology. 423: 36P.  0.631
1989 Rakic LM, Zlokovic BV, Davson H, Segal MB, Begley DJ, Lipovac MN, Mitrovic DM. Chronic amphetamine intoxication and the blood-brain barrier permeability to inert polar molecules studied in the vascularly perfused guinea pig brain. Journal of the Neurological Sciences. 94: 41-50. PMID 2515257 DOI: 10.1016/0022-510X(89)90216-5  0.628
1989 Preston JE, Segal MB, Walley GJ, Zlokovic BV. Neutral amino acid uptake by the isolated perfused sheep choroid plexus. The Journal of Physiology. 408: 31-43. PMID 2506339 DOI: 10.1113/jphysiol.1989.sp017444  0.425
1989 Rakic LM, Zlokovic BV, Segal MB, Lipovac MH, Mitrovic DM, Veskov R, Mackic JB, Davson H. Effects of sensory-motor cortical lesions on blood-brain permeability in guinea pigs. Metabolic Brain Disease. 4: 9-15. PMID 2495423 DOI: 10.1007/Bf00999488  0.613
1989 Zlokovic BV, Skundric DS, Segal MB, Colover J, Jankov RM, Pejnovic N, Lackovic V, Mackic J, Lipovac MN, Davson H. Blood-brain barrier permeability changes during acute allergic encephalomyelitis induced in the guinea pig. Metabolic Brain Disease. 4: 33-40. PMID 2495422 DOI: 10.1007/Bf00999491  0.675
1988 Zlokovic BV, Segal MB, Davson H, Jankov RM. Passage of delta sleep-inducing peptide (DSIP) across the blood-cerebrospinal fluid barrier. Peptides. 9: 533-8. PMID 3420012 DOI: 10.1016/0196-9781(88)90160-X  0.642
1988 Zlokovic BV, Segal MB, Davson H, Mitrovic DM. Unidirectional uptake of enkephalins at the blood-tissue interface of the blood-cerebrospinal fluid barrier: a saturable mechanism. Regulatory Peptides. 20: 33-44. PMID 3127863 DOI: 10.1016/0167-0115(88)90055-9  0.631
1987 Zlokovic BV, Davson H, Preston JE, Segal MB. The effects of aluminum chloride on the rate of secretion of the cerebrospinal fluid. Experimental Neurology. 98: 436-52. PMID 2444450 DOI: 10.1016/0014-4886(87)90253-6  0.601
1985 Zlokovi? BV, Segal MB, Begley DJ, Davson H, Raki? L. Permeability of the blood-cerebrospinal fluid and blood-brain barriers to thyrotropin-releasing hormone. Brain Research. 358: 191-9. PMID 3935272 DOI: 10.1016/0006-8993(85)90963-1  0.684
1978 Davson H, Segal MB. Introduction to physiology, vol. 4 . I-XII+621 p.; £11.80.  0.457
1974 Evans CA, Reynolds JM, Reynolds ML, Saunders NR, Segal MB. The development of a blood-brain barrier mechanism in foetal sheep. The Journal of Physiology. 238: 371-86. PMID 4601383 DOI: 10.1113/jphysiol.1974.sp010530  0.317
1972 Evans CA, Reynolds JM, Reynolds M, Saunders NR, Segal MB. The development of blood-brain barrier and choroid plexus function in immature foetal sheep. The Journal of Physiology. 224: 15P-16P. PMID 5039976  0.386
1972 Bradbury MW, Segal MB, Wilson J. Transport of potassium at the blood-brain barrier. The Journal of Physiology. 221: 617-32. PMID 5016363 DOI: 10.1113/jphysiol.1972.sp009771  0.666
1971 Davson H, Segal MB. Secretion and drainage of the cerebrospinal fluid. Acta NeurolóGica Latinoamericana. 1: Suppl 1:99-118. PMID 5172640  0.537
1971 Evans CAN, Reyolds J, Reynolds M, Saunders NR, Segal MB. 42. Effect of hypercapnia on a blood-brain barrier in fetal and neonatal sheep Pediatric Research. 5: 92-92. DOI: 10.1203/00006450-197102000-00047  0.382
1970 Davson H, Segal MB. The effects of some inhibitors and accelerators of sodium transport on the turnover of 22Na in the cerebrospinal fluid and the brain. The Journal of Physiology. 209: 131-53. PMID 5499038 DOI: 10.1113/jphysiol.1970.sp009159  0.604
1970 Davson H, Hollingsworth G, Segal MB. The mechanism of drainage of the cerebrospinal fluid. Brain : a Journal of Neurology. 93: 665-78. PMID 5490270 DOI: 10.1093/brain/93.4.665  0.573
1969 Davson H, Purvis CA, Segal MB. Measurement of resistance to flow of cerebrospinal fluid. The Journal of Physiology. 202: 62P-64P. PMID 5784306  0.494
1969 Davson H, Segal MB. Effect of cerebrospinal fluid on volume of distribution of extracellular markers. Brain : a Journal of Neurology. 92: 131-6. PMID 5774024 DOI: 10.1093/brain/92.1.131  0.524
1969 Cameron IR, Davson H, Segal MB. The effect of hypercapnia on the blood-brain barrier to sucrose in the rabbit. The Yale Journal of Biology and Medicine. 42: 241-7. PMID 5371163  0.634
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