Renae Monique Ryan - Publications

University of Sydney, Camperdown, New South Wales, Australia 

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Chen I, Pant S, Wu Q, Cater RJ, Sobti M, Vandenberg RJ, Stewart AG, Tajkhorshid E, Font J, Ryan RM. Glutamate transporters have a chloride channel with two hydrophobic gates. Nature. PMID 33597752 DOI: 10.1038/s41586-021-03240-9  1
2020 Freidman N, Chen I, Wu Q, Briot C, Holst J, Font J, Vandenberg R, Ryan R. Amino Acid Transporters and Exchangers from the SLC1A Family: Structure, Mechanism and Roles in Physiology and Cancer. Neurochemical Research. PMID 31981058 DOI: 10.1007/S11064-019-02934-X  0.64
2019 Mostyn SN, Wilson KA, Schumann-Gillett A, Frangos ZJ, Shimmon S, Rawling T, Ryan RM, O'Mara ML, Vandenberg RJ. Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics. Elife. 8. PMID 31621581 DOI: 10.7554/Elife.47150  1
2019 Mostyn SN, Rawling T, Mohammadi S, Shimmon S, Frangos ZJ, Sarker S, Yousuf A, Vetter I, Ryan RM, Christie MJ, Vandenberg RJ. Development of an N-acyl amino acid that selectively inhibits the glycine transporter 2 to produce analgesia in a rat model of chronic pain. Journal of Medicinal Chemistry. PMID 30714733 DOI: 10.1021/Acs.Jmedchem.8B01775  1
2018 van Geldermalsen M, Quek LE, Turner N, Freidman N, Pang A, Guan YF, Krycer JR, Ryan R, Wang Q, Holst J. Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways. Bmc Cancer. 18: 689. PMID 29940911 DOI: 10.1186/S12885-018-4599-8  0.36
2018 Scopelliti AJ, Font J, Vandenberg RJ, Boudker O, Ryan RM. Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5. Nature Communications. 9: 38. PMID 29295993 DOI: 10.1038/S41467-017-02444-W  1
2017 Carland JE, Thomas M, Mostyn SN, Subramanian N, O'Mara ML, Ryan RM, Vandenberg RJ. Molecular Determinants for Substrate Interactions with the Glycine Transporter GlyT2. Acs Chemical Neuroscience. PMID 29120604 DOI: 10.1021/Acschemneuro.7B00407  1
2017 Mostyn SN, Carland JE, Shimmon S, Ryan RM, Rawling T, Vandenberg RJ. Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2. Acs Chemical Neuroscience. PMID 28574249 DOI: 10.1021/Acschemneuro.7B00105  1
2016 Krycer JR, Fazakerley DJ, Cater RJ, Thomas K, Naghiloo S, Burchfield JG, Humphrey SJ, Vandenberg RJ, Ryan RM, James DE. The amino acid transporter SLC1A3 is plasma membrane-localised in adipocytes and its activity is insensitive to insulin. Febs Letters. PMID 28032905 DOI: 10.1002/1873-3468.12549  1
2016 McIlwain BC, Vandenberg RJ, Ryan RM. Characterization of the Inward- and Outward-Facing Substrate Binding Sites of the Prokaryotic Aspartate Transporter, GltPh. Biochemistry. 55: 6801-6810. PMID 27951659 DOI: 10.1021/Acs.Biochem.6B00795  1
2016 Vandenberg RJ, Ryan R, Broer S. Brain transporters: From genes and genetic disorders to function and drug discovery. Neurochemistry International. 98: 1-3. PMID 27475459 DOI: 10.1016/J.Neuint.2016.07.005  1
2016 Subramanian N, Scopelliti AJ, Carland JE, Ryan RM, O'Mara ML, Vandenberg RJ. Correction: Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2. Plos One. 11: e0159896. PMID 27434127 DOI: 10.1371/Journal.Pone.0159896  1
2016 Subramanian N, Scopelitti AJ, Carland JE, Ryan RM, O'Mara ML, Vandenberg RJ. Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2. Plos One. 11: e0157583. PMID 27337045 DOI: 10.1371/Journal.Pone.0157583  1
2016 Cater RJ, Vandenberg RJ, Ryan RM. Tuning the ion selectivity of glutamate transporter-associated uncoupled conductances. The Journal of General Physiology. PMID 27296367 DOI: 10.1085/Jgp.201511556  1
2016 Ryan RM, Vandenberg RJ. Elevating the alternating-access model. Nature Structural & Molecular Biology. 23: 187-9. PMID 26931415 DOI: 10.1038/Nsmb.3179  1
2015 Vandenberg RJ, Mostyn SN, Carland JE, Ryan RM. Glycine Transporter2 Inhibitors: Getting the balance right. Neurochemistry International. PMID 26723543 DOI: 10.1016/J.Neuint.2015.12.007  1
2015 Cater RJ, Ryan RM, Vandenberg RJ. The Split Personality of Glutamate Transporters: A Chloride Channel and a Transporter. Neurochemical Research. PMID 26303507 DOI: 10.1007/S11064-015-1699-6  1
2015 Vinh NB, Devine SM, Munoz L, Ryan RM, Wang BH, Krum H, Chalmers DK, Simpson JS, Scammells PJ. Design, Synthesis, and Biological Evaluation of Tetra-Substituted Thiophenes as Inhibitors of p38α MAPK. Chemistryopen. 4: 56-64. PMID 25861571 DOI: 10.1002/Open.201402076  1
2015 McIlwain BC, Vandenberg RJ, Ryan RM. Transport rates of a glutamate transporter homologue are influenced by the lipid bilayer. The Journal of Biological Chemistry. 290: 9780-8. PMID 25713135 DOI: 10.1074/Jbc.M114.630590  1
2014 Cater RJ, Vandenberg RJ, Ryan RM. The domain interface of the human glutamate transporter EAAT1 mediates chloride permeation. Biophysical Journal. 107: 621-9. PMID 25099801 DOI: 10.1016/J.Bpj.2014.05.046  1
2014 Vandenberg RJ, Ryan RM, Carland JE, Imlach WL, Christie MJ. Glycine transport inhibitors for the treatment of pain. Trends in Pharmacological Sciences. 35: 423-30. PMID 24962068 DOI: 10.1016/J.Tips.2014.05.006  1
2014 Scopelliti AJ, Heinzelmann G, Kuyucak S, Ryan RM, Vandenberg RJ. Na+ interactions with the neutral amino acid transporter ASCT1. The Journal of Biological Chemistry. 289: 17468-79. PMID 24808181 DOI: 10.1074/Jbc.M114.565242  1
2014 Wang Q, Grkovic T, Font J, Bonham S, Pouwer RH, Bailey CG, Moran AM, Ryan RM, Rasko JE, Jormakka M, Quinn RJ, Holst J. Monoterpene glycoside ESK246 from Pittosporum targets LAT3 amino acid transport and prostate cancer cell growth. Acs Chemical Biology. 9: 1369-76. PMID 24762008 DOI: 10.1021/Cb500120X  1
2014 Wang Q, Beaumont KA, Otte NJ, Font J, Bailey CG, van Geldermalsen M, Sharp DM, Tiffen JC, Ryan RM, Jormakka M, Haass NK, Rasko JE, Holst J. Targeting glutamine transport to suppress melanoma cell growth. International Journal of Cancer. Journal International Du Cancer. 135: 1060-71. PMID 24531984 DOI: 10.1002/Ijc.28749  1
2014 Carland JE, Handford CA, Ryan RM, Vandenberg RJ. Lipid inhibitors of high affinity glycine transporters: identification of a novel class of analgesics. Neurochemistry International. 73: 211-6. PMID 24036283 DOI: 10.1016/J.Neuint.2013.08.012  1
2013 Vandenberg RJ, Ryan RM. Mechanisms of glutamate transport. Physiological Reviews. 93: 1621-57. PMID 24137018 DOI: 10.1152/Physrev.00007.2013  1
2013 Scopelliti AJ, Ryan RM, Vandenberg RJ. Molecular determinants for functional differences between alanine-serine-cysteine transporter 1 and other glutamate transporter family members. The Journal of Biological Chemistry. 288: 8250-7. PMID 23393130 DOI: 10.1074/Jbc.M112.441022  1
2013 Carland JE, Mansfield RE, Ryan RM, Vandenberg RJ. Oleoyl-L-carnitine inhibits glycine transport by GlyT2. British Journal of Pharmacology. 168: 891-902. PMID 22978602 DOI: 10.1111/J.1476-5381.2012.02213.X  1
2012 Bastug T, Heinzelmann G, Kuyucak S, Salim M, Vandenberg RJ, Ryan RM. Position of the third Na+ site in the aspartate transporter GltPh and the human glutamate transporter, EAAT1. Plos One. 7: e33058. PMID 22427946 DOI: 10.1371/Journal.Pone.0033058  1
2011 Vandenberg RJ, Handford CA, Campbell EM, Ryan RM, Yool AJ. Water and urea permeation pathways of the human excitatory amino acid transporter EAAT1. The Biochemical Journal. 439: 333-40. PMID 21732909 DOI: 10.1042/Bj20110905  1
2011 Bailey CG, Ryan RM, Thoeng AD, Ng C, King K, Vanslambrouck JM, Auray-Blais C, Vandenberg RJ, Bröer S, Rasko JE. Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria. The Journal of Clinical Investigation. 121: 446-53. PMID 21123949 DOI: 10.1172/Jci44474  1
2010 Ryan RM, Kortt NC, Sirivanta T, Vandenberg RJ. The position of an arginine residue influences substrate affinity and K+ coupling in the human glutamate transporter, EAAT1. Journal of Neurochemistry. 114: 565-75. PMID 20477940 DOI: 10.1111/J.1471-4159.2010.06796.X  1
2010 McKinzie AA, Ryan RM, Vandenberg RJ. Site-directed mutagenesis in the study of membrane transporters. Methods in Molecular Biology (Clifton, N.J.). 637: 277-93. PMID 20419441 DOI: 10.1007/978-1-60761-700-6_15  1
2009 Edington AR, McKinzie AA, Reynolds AJ, Kassiou M, Ryan RM, Vandenberg RJ. Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transport. The Journal of Biological Chemistry. 284: 36424-30. PMID 19875446 DOI: 10.1074/Jbc.M109.017509  1
2009 Ryan RM, Compton EL, Mindell JA. Functional characterization of a Na+-dependent aspartate transporter from Pyrococcus horikoshii. The Journal of Biological Chemistry. 284: 17540-8. PMID 19380583 DOI: 10.1074/Jbc.M109.005926  1
2009 Huang S, Ryan RM, Vandenberg RJ. The role of cation binding in determining substrate selectivity of glutamate transporters. The Journal of Biological Chemistry. 284: 4510-5. PMID 19074430 DOI: 10.1074/Jbc.M808495200  1
2008 Vandenberg RJ, Huang S, Ryan RM. Slips, leaks and channels in glutamate transporters. Channels (Austin, Tex.). 2: 51-8. PMID 18690049 DOI: 10.4161/Chan.2.1.6047  1
2007 Ryan RM, Mindell JA. The uncoupled chloride conductance of a bacterial glutamate transporter homolog. Nature Structural & Molecular Biology. 14: 365-71. PMID 17435767 DOI: 10.1038/Nsmb1230  1
2007 Boudker O, Ryan RM, Yernool D, Shimamoto K, Gouaux E. Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter. Nature. 445: 387-93. PMID 17230192 DOI: 10.1038/Nature05455  1
2005 Vandenberg RJ, Ryan RM. How and why are channels in transporters? Science's Stke : Signal Transduction Knowledge Environment. 2005: pe17. PMID 15840837 DOI: 10.1126/Stke.2802005Pe17  1
2005 Ryan RM, Vandenberg RJ. A channel in a transporter. Clinical and Experimental Pharmacology & Physiology. 32: 1-6. PMID 15730426 DOI: 10.1111/J.1440-1681.2005.04164.X  1
2004 Jennings EA, Ryan RM, Christie MJ. Effects of sumatriptan on rat medullary dorsal horn neurons. Pain. 111: 30-7. PMID 15327806 DOI: 10.1016/J.Pain.2004.05.018  1
2004 Vandenberg RJ, Ju P, Aubrey KR, Ryan RM, Mitrovic AD. Allosteric modulation of neurotransmitter transporters at excitatory synapses. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 23: 1-11. PMID 15324920 DOI: 10.1016/J.Ejps.2004.05.006  1
2004 Ryan RM, Mitrovic AD, Vandenberg RJ. The chloride permeation pathway of a glutamate transporter and its proximity to the glutamate translocation pathway. The Journal of Biological Chemistry. 279: 20742-51. PMID 14982939 DOI: 10.1074/Jbc.M304433200  1
2003 Ryan RM, Mitrovic AD, Vandenberg RJ. Site-directed mutagenesis in the study of membrane transporters. Methods in Molecular Biology (Clifton, N.J.). 227: 97-108. PMID 12824646 DOI: 10.1385/1-59259-387-9:97  1
2002 Borgland SL, Connor M, Ryan RM, Ball HJ, Christie MJ. Prostaglandin E(2) inhibits calcium current in two sub-populations of acutely isolated mouse trigeminal sensory neurons. The Journal of Physiology. 539: 433-44. PMID 11882676 DOI: 10.1113/Jphysiol.2001.013322  1
2002 Ryan RM, Vandenberg RJ. Distinct conformational states mediate the transport and anion channel properties of the glutamate transporter EAAT-1. The Journal of Biological Chemistry. 277: 13494-500. PMID 11815608 DOI: 10.1074/Jbc.M109970200  1
1993 Ryan RM, Rigby S, King K. Two types of religious internalization and their relations to religious orientations and mental health. Journal of Personality and Social Psychology. 65: 586-96. PMID 8410653  0.32
Show low-probability matches.