Eva L. Feldman - Publications

Neuroscience University of Michigan, Ann Arbor, Ann Arbor, MI 
Neuroscience Biology, Pathology

219 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Feldman EL, Savelieff MG, Hayek SS, Pennathur S, Kretzler M, Pop-Busui R. COVID-19 and Diabetes: A Collision and Collusion of Two Diseases. Diabetes. PMID 32938731 DOI: 10.2337/Dbi20-0032  0.344
2020 Guo K, Eid SA, Elzinga SE, Pacut C, Feldman EL, Hur J. Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy. Clinical Epigenetics. 12: 123. PMID 32787975 DOI: 10.1186/S13148-020-00913-6  0.333
2020 Stino AM, Rumora AE, Kim B, Feldman EL. Evolving concepts on the role of dyslipidemia, bioenergetics, and inflammation in the pathogenesis and treatment of diabetic peripheral neuropathy. Journal of the Peripheral Nervous System : Jpns. PMID 32412144 DOI: 10.1111/Jns.12387  0.373
2020 Christensen DH, Knudsen ST, Gylfadottir SS, Christensen LB, Nielsen JS, Beck-Nielsen H, Sørensen HT, Andersen H, Callaghan BC, Feldman EL, Finnerup NB, Jensen TS, Thomsen RW. Metabolic Factors, Lifestyle Habits, and Possible Polyneuropathy in Early Type 2 Diabetes: A Nationwide Study of 5,249 Patients in the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Cohort. Diabetes Care. PMID 32295810 DOI: 10.2337/Dc19-2277  0.353
2020 Savelieff MG, Callaghan BC, Feldman EL. The emerging role of dyslipidemia in diabetic microvascular complications. Current Opinion in Endocrinology, Diabetes, and Obesity. 27: 115-123. PMID 32073426 DOI: 10.1097/Med.0000000000000533  0.353
2020 Braffett BH, Gubitosi-Klug RA, Albers JW, Feldman EL, Martin CL, White NH, Orchard TJ, Lopes-Virella M, Lachin JM, Pop-Busui R. Risk Factors for Diabetic Peripheral Neuropathy and Cardiovascular Autonomic Neuropathy in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study. Diabetes. PMID 32051148 DOI: 10.2337/Db19-1046  0.344
2020 Callaghan BC, Gallagher G, Fridman V, Feldman EL. Diabetic neuropathy: what does the future hold? Diabetologia. PMID 31974731 DOI: 10.1007/S00125-020-05085-9  0.356
2020 Reynolds EL, Nelson RG, Akinci G, Henn R, Patterson A, Feldman EL, Callaghan BC. 532-P: The Longitudinal Determinants of Diabetic Complications in the Pima Indians of Arizona Diabetes. 69. DOI: 10.2337/Db20-532-P  0.312
2020 Rumora AE, Alakwaa F, Andersen ST, Jørgensen ME, Charles M, Callaghan BC, Jensen TS, Feldman EL. 531-P: Metabolomics Identifies Novel Plasma Metabolomic Signatures Associated with Diabetic Neuropathy in a Cohort with Screen-Tested Type 2 Diabetes: ADDITION-Denmark Diabetes. 69. DOI: 10.2337/Db20-531-P  0.348
2020 Eid S, Hinder LM, Hayes JM, Mendelson F, Feldman EL. 529-P: Insulin Replacement Therapy Does Not Fully Prevent Peripheral Neuropathy in Type 1 Diabetic Mice Diabetes. 69. DOI: 10.2337/Db20-529-P  0.351
2019 O'Brien PD, Guo K, Eid SA, Rumora AE, Hinder LM, Hayes JM, Mendelson FE, Hur J, Feldman EL. Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes. Disease Models & Mechanisms. PMID 31822493 DOI: 10.1242/Dmm.042101  0.36
2019 Afshinnia F, Nair V, Lin J, Rajendiran TM, Soni T, Byun J, Sharma K, Fort PE, Gardner TW, Looker HC, Nelson RG, Brosius FC, Feldman EL, Michailidis G, Kretzler M, et al. Increased lipogenesis and impaired β-oxidation predict type 2 diabetic kidney disease progression in American Indians. Jci Insight. PMID 31573977 DOI: 10.1172/Jci.Insight.130317  0.332
2019 Kim B, Elzinga SE, Henn RE, McGinley LM, Feldman EL. The effects of insulin and insulin-like growth factor I on amyloid precursor protein phosphorylation in in vitro and in vivo models of Alzheimer's disease. Neurobiology of Disease. 104541. PMID 31349033 DOI: 10.1016/J.Nbd.2019.104541  0.321
2019 Eid S, Sas KM, Abcouwer SF, Feldman EL, Gardner TW, Pennathur S, Fort PE. New insights into the mechanisms of diabetic complications: role of lipids and lipid metabolism. Diabetologia. PMID 31346658 DOI: 10.1007/S00125-019-4959-1  0.364
2019 Rumora AE, Savelieff MG, Sakowski SA, Feldman EL. Disorders of mitochondrial dynamics in peripheral neuropathy: Clues from hereditary neuropathy and diabetes. International Review of Neurobiology. 145: 127-176. PMID 31208522 DOI: 10.1016/Bs.Irn.2019.05.002  0.365
2019 Goutman SA, Savelieff MG, Sakowski SA, Feldman EL. Stem cell treatments for amyotrophic lateral sclerosis: a critical overview of early phase trials. Expert Opinion On Investigational Drugs. 1-19. PMID 31189354 DOI: 10.1080/13543784.2019.1627324  0.301
2019 Elzinga S, Murdock BJ, Guo K, Hayes JM, Tabbey MA, Hur J, Feldman EL. Toll-like receptors and inflammation in metabolic neuropathy; a role in early versus late disease? Experimental Neurology. 112967. PMID 31145897 DOI: 10.1016/J.Expneurol.2019.112967  0.317
2019 Guo K, Elzinga S, Eid S, Figueroa-Romero C, Hinder LM, Pacut C, Feldman EL, Hur J. Genome-wide DNA methylation profiling of human diabetic peripheral neuropathy in subjects with type 2 diabetes mellitus. Epigenetics. 1-14. PMID 31132961 DOI: 10.1080/15592294.2019.1615352  0.345
2019 Rumora AE, LoGrasso G, Hayes JM, Mendelson FE, Tabbey MA, Haidar JA, Lentz SI, Feldman EL. The divergent roles of dietary saturated and monounsaturated fatty acids on nerve function in murine models of obesity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30886017 DOI: 10.1523/Jneurosci.3173-18.2019  0.358
2019 de Anda-Jáuregui G, Guo K, McGregor BA, Feldman EL, Hur J. Correction to: Pathway crosstalk perturbation network modeling for identification of connectivity changes induced by diabetic neuropathy and pioglitazone. Bmc Systems Biology. 13: 31. PMID 30866938 DOI: 10.1186/S12918-019-0707-X  0.322
2019 Hinder LM, Sas KM, O'Brien PD, Backus C, Kayampilly P, Hayes JM, Lin CM, Zhang H, Shanmugam S, Rumora AE, Abcouwer SF, Brosius FC, Pennathur S, Feldman EL. Mitochondrial uncoupling has no effect on microvascular complications in type 2 diabetes. Scientific Reports. 9: 881. PMID 30696927 DOI: 10.1038/S41598-018-37376-Y  0.377
2019 Braffett B, Gubitosi-Klug R, Albers JW, Feldman EL, Martin C, White NH, Orchard TJ, Lopes-Virella MF, Raskin P, Pop-Busui R. 322-OR: Risk Factors for Peripheral and Cardiovascular Autonomic Neuropathy in Type 1 Diabetes: Thirty Years of Follow-Up in DCCT/EDIC Diabetes. 68. DOI: 10.2337/Db19-322-Or  0.338
2019 GUO K, FELDMAN EL, HUR J. 31-LB: Identification of Repurposable Drug Candidate for Diabetic Peripheral Neuropathy Using High-Throughput Drug-Perturbation Data Diabetes. 68: 31-LB. DOI: 10.2337/Db19-31-Lb  0.322
2018 McGregor BA, Eid S, Rumora AE, Murdock B, Guo K, de Anda-Jáuregui G, Porter JE, Feldman EL, Hur J. Conserved Transcriptional Signatures in Human and Murine Diabetic Peripheral Neuropathy. Scientific Reports. 8: 17678. PMID 30518872 DOI: 10.1038/S41598-018-36098-5  0.359
2018 O'Brien PD, Hinder LM, Rumora AE, Hayes JM, Dauch JR, Backus C, Mendelson FE, Feldman EL. Juvenile murine models of prediabetes and type 2 diabetes develop neuropathy. Disease Models & Mechanisms. PMID 30446513 DOI: 10.1242/Dmm.037374  0.337
2018 Hinder LM, Murdock BJ, Park M, Bender DE, O'Brien PD, Rumora AE, Hur J, Feldman EL. Transcriptional networks of progressive diabetic peripheral neuropathy in the db/db mouse model of type 2 diabetes: An inflammatory story. Experimental Neurology. PMID 29550371 DOI: 10.1016/J.Expneurol.2018.03.011  0.382
2018 Andersen ST, Witte DR, Dalsgaard EM, Andersen H, Nawroth P, Fleming T, Jensen TM, Finnerup NB, Jensen TS, Lauritzen T, Feldman EL, Callaghan BC, Charles M. Risk Factors for Incident Diabetic Polyneuropathy in a Cohort With Screen-Detected Type 2 Diabetes Followed for 13 Years: ADDITION-Denmark. Diabetes Care. PMID 29487078 DOI: 10.2337/Dc17-2062  0.336
2018 Jaiswal M, Divers J, Pop-Busui R, Feldman EL. Response to Comment on Jaiswal et al. Prevalence of and Risk Factors for Diabetic Peripheral Neuropathy in Youth With Type 1 and Type 2 Diabetes: SEARCH for Diabetes in Youth Study. Diabetes Care 2017;40:1226-1232. Diabetes Care. 41: e37. PMID 29463674 DOI: 10.2337/Dci17-0058  0.355
2018 Jaiswal M, Divers J, Urbina EM, Dabelea D, Bell RA, Pettitt DJ, Imperatore G, Pihoker C, Dolan LM, Liese AD, Marcovina S, Linder B, Feldman EL, Pop-Busui R. Cardiovascular autonomic neuropathy in adolescents and young adults with type 1 and type 2 diabetes: The SEARCH for Diabetes in Youth Cohort Study. Pediatric Diabetes. PMID 29292558 DOI: 10.1111/Pedi.12633  0.319
2018 SAJIC M, KANHAI A, DENTONI G, VARATHARAJAH S, HINDER LM, RUMORA A, FELDMAN EL, SMITH K. High-Fat Diet Induces Mitochondrial Dysfunction in Saphenous Nerve Axons—A Study by Confocal Microscopy In Vivo Diabetes. 67: 60-OR. DOI: 10.2337/Db18-60-Or  0.318
2018 RUMORA A, LOGRASSO G, HAIDAR JA, DOLKOWSKI J, LENTZ SI, FELDMAN EL. Monounsaturated Fatty Acids Prevent Saturated Fatty Acid–Induced Impairment of Mitochondrial Trafficking in Dorsal Root Ganglion Sensory Neurons Diabetes. 67: 573-P. DOI: 10.2337/Db18-573-P  0.311
2018 O'BRIEN PD, GUO K, HINDER LM, HAYES JM, MENDELSON F, TABBEY MA, HUR J, FELDMAN EL. Amelioration of Peripheral Neuropathy in Mouse Models of Diabetes by Dietary Reversal Diabetes. 67: 569-P. DOI: 10.2337/Db18-569-P  0.319
2018 GUO K, ELZINGA S, EID S, FIGUEROA-ROMERO C, MCGREGOR BA, DE ANDA-JÁUREGUI G, PACUT C, FELDMAN EL, HUR J. Large-Scale DNA Methylation Profiling of Human Diabetic Peripheral Neuropathy in Subjects with Type 2 Diabetes Mellitus Diabetes. 67: 551-P. DOI: 10.2337/Db18-551-P  0.353
2018 ELZINGA S, MURDOCK B, HAYES JM, TABBEY MA, FELDMAN EL. Toll-Like Receptors 2/4 and Diabetic Peripheral Neuropathy Diabetes. 67: 32-LB. DOI: 10.2337/Db18-32-Lb  0.303
2018 LOGRASSO G, RUMORA A, HAIDAR JA, LENTZ SI, FELDMAN EL. Saturated Fatty Acids Impair Organellar Trafficking in Dorsal Root Ganglion (DRG) Sensory Neurons Diabetes. 67: 31-LB. DOI: 10.2337/Db18-31-Lb  0.319
2018 EID S, HAYES JM, GUO K, PACUT C, MENDELSON F, HUR J, FELDMAN EL. NOX, NOX, Are You Here? The Emerging Role of NOX5 in Diabetic Neuropathy Diabetes. 67: 30-LB. DOI: 10.2337/Db18-30-Lb  0.354
2017 Jaiswal M, Divers J, Dabelea D, Isom S, Bell RA, Martin CL, Pettitt DJ, Saydah S, Pihoker C, Standiford DA, Dolan LM, Marcovina S, Linder B, Liese AD, Pop-Busui R, ... Feldman EL, et al. Prevalence of and Risk Factors for Diabetic Peripheral Neuropathy in Youth With Type 1 and Type 2 Diabetes: SEARCH for Diabetes in Youth Study. Diabetes Care. PMID 28674076 DOI: 10.2337/Dc17-0179  0.348
2017 Hinder LM, O'Brien PD, Hayes JM, Backus C, Solway AP, Sims-Robinson C, Feldman EL. Dietary reversal of neuropathy in a murine model of prediabetes and the metabolic syndrome. Disease Models & Mechanisms. PMID 28381495 DOI: 10.1242/Dmm.028530  0.313
2017 Feldman EL, Nave KA, Jensen TS, Bennett DL. New Horizons in Diabetic Neuropathy: Mechanisms, Bioenergetics, and Pain. Neuron. 93: 1296-1313. PMID 28334605 DOI: 10.1016/J.Neuron.2017.02.005  0.374
2017 O'Brien PD, Hinder LM, Parlee SD, Hayes JM, Backus C, Zhang H, Ma L, Sakowski SA, Brosius FC, Feldman EL. Dual CCR2/CCR5 antagonist treatment attenuates adipose inflammation, but not microvascular complications in ob/ob mice. Diabetes, Obesity & Metabolism. PMID 28332276 DOI: 10.1111/Dom.12950  0.345
2017 Hinder LM, Park M, Rumora AE, Hur J, Eichinger F, Pennathur S, Kretzler M, Brosius FC, Feldman EL. Comparative RNA-Seq transcriptome analyses reveal distinct metabolic pathways in diabetic nerve and kidney disease. Journal of Cellular and Molecular Medicine. PMID 28272773 DOI: 10.1111/Jcmm.13136  0.381
2017 Grisold A, Callaghan BC, Feldman EL. Mediators of diabetic neuropathy: is hyperglycemia the only culprit? Current Opinion in Endocrinology, Diabetes, and Obesity. PMID 28098594 DOI: 10.1097/Med.0000000000000320  0.369
2017 Pop-Busui R, Boulton AJ, Feldman EL, Bril V, Freeman R, Malik RA, Sosenko JM, Ziegler D. Diabetic Neuropathy: A Position Statement by the American Diabetes Association. Diabetes Care. 40: 136-154. PMID 27999003 DOI: 10.2337/Dc16-2042  0.37
2017 Lovblom LE, Bril V, Orszag A, Edwards K, Pritchard N, Russel A, Pacaud D, Romanchuk K, Mah J, Jeziorska M, Marshall A, Shtein RM, Pop-Busui R, Feldman EL, Boulton AJ. Exploring the optimal diagnostic threshold value of corneal nerve fibre length (CNFL) for diabetic neuropathy (DN) identification Canadian Journal of Diabetes. 41: S62. DOI: 10.1016/J.Jcjd.2017.08.172  0.326
2016 Sas KM, Kayampilly P, Byun J, Nair V, Hinder LM, Hur J, Zhang H, Lin C, Qi NR, Michailidis G, Groop PH, Nelson RG, Darshi M, Sharma K, Schelling JR, ... ... Feldman EL, et al. Tissue-specific metabolic reprogramming drives nutrient flux in diabetic complications. Jci Insight. 1: e86976. PMID 27699244 DOI: 10.1172/Jci.Insight.86976  0.353
2016 Wheelock KM, Jaiswal M, Martin CL, Fufaa GD, Weil EJ, Lemley KV, Yee B, Feldman E, Brosius FC, Knowler WC, Nelson RG, Pop-Busui R. Cardiovascular autonomic neuropathy associates with nephropathy lesions in American Indians with type 2 diabetes. Journal of Diabetes and Its Complications. PMID 27041674 DOI: 10.1016/J.Jdiacomp.2016.03.008  0.321
2016 Hur J, O'Brien PD, Nair V, Hinder LM, McGregor BA, Jagadish HV, Kretzler M, Brosius FC, Feldman EL. Transcriptional networks of murine diabetic peripheral neuropathy and nephropathy: common and distinct gene expression patterns. Diabetologia. PMID 27000313 DOI: 10.1007/S00125-016-3913-8  0.361
2016 Jaiswal M, Fufaa GD, Martin CL, Pop-Busui R, Nelson RG, Feldman EL. Burden of Diabetic Peripheral Neuropathy in Pima Indians With Type 2 Diabetes. Diabetes Care. PMID 26908916 DOI: 10.2337/Dc16-0082  0.339
2016 Pop-Busui R, Ang L, Holmes C, Gallagher K, Feldman EL. Inflammation as a Therapeutic Target for Diabetic Neuropathies. Current Diabetes Reports. 16: 29. PMID 26897744 DOI: 10.1007/S11892-016-0727-5  0.364
2016 McGinley LM, Sims E, Lunn JS, Kashlan ON, Chen KS, Bruno ES, Pacut CM, Hazel T, Johe K, Sakowski SA, Feldman EL. Human Cortical Neural Stem Cells Expressing Insulin-Like Growth Factor-I: A Novel Cellular Therapy for Alzheimer's Disease. Stem Cells Translational Medicine. PMID 26744412 DOI: 10.5966/Sctm.2015-0103  0.327
2016 Stables CL, Auerbach DS, Whitesall SE, D'Alecy LG, Feldman EL. Differential impact of type-1 and type-2 diabetes on control of heart rate in mice. Autonomic Neuroscience : Basic & Clinical. 194: 17-25. PMID 26725752 DOI: 10.1016/J.Autneu.2015.12.006  0.328
2016 Perkins BA, Lovblom LE, Bril V, Edwards K, Pritchard N, Russell A, Pacaud D, Romanchuk K, Mah J, Boulton A, Jeziorska M, Marshall A, Shtein RM, Pop-Busui R, Feldman EL, et al. Results of an International Corneal Confocal Microscopy (CCM) Consortium: A Pooled Multicentre Analysis of the Concurrent Diagnostic Validity of CCM to Identify Diabetic Polyneuropathy in Type 1 Diabetes Mellitus Canadian Journal of Diabetes. 40: S20. DOI: 10.1016/J.Jcjd.2016.08.062  0.343
2015 Chen KS, Sakowski SA, Feldman EL. Intraspinal Stem Cell Transplantation for Amyotrophic Lateral Sclerosis. Annals of Neurology. PMID 26696091 DOI: 10.1002/Ana.24584  0.309
2015 O'Brien PD, Hur J, Robell NJ, Hayes JM, Sakowski SA, Feldman EL. Gender-specific differences in diabetic neuropathy in BTBR ob/ob mice. Journal of Diabetes and Its Complications. PMID 26525588 DOI: 10.1016/J.Jdiacomp.2015.09.018  0.338
2015 Jaiswal M, Martin CL, Brown MB, Callaghan B, Albers JW, Feldman EL, Pop-Busui R. Effects of exenatide on measures of diabetic neuropathy in subjects with type 2 diabetes: results from an 18-month proof-of-concept open-label randomized study. Journal of Diabetes and Its Complications. PMID 26264399 DOI: 10.1016/J.Jdiacomp.2015.07.013  0.354
2015 Kim B, Figueroa-Romero C, Pacut C, Backus C, Feldman EL. Insulin resistance prevents AMPK-induced tau dephosphorylation through Akt-mediated increase in AMPKSer485 phosphorylation. The Journal of Biological Chemistry. PMID 26100639 DOI: 10.1074/Jbc.M115.636852  0.317
2015 Hur J, Dauch JR, Hinder LM, Hayes JM, Backus C, Pennathur S, Kretzler M, Brosius FC, Feldman EL. The Metabolic Syndrome and Microvascular Complications in a Murine Model of Type 2 Diabetes. Diabetes. PMID 25979075 DOI: 10.2337/Db15-0133  0.367
2015 Sims-Robinson C, Bakeman A, Rosko A, Glasser R, Feldman EL. The Role of Oxidized Cholesterol in Diabetes-Induced Lysosomal Dysfunction in the Brain. Molecular Neurobiology. PMID 25976368 DOI: 10.1007/S12035-015-9207-1  0.377
2015 Kim B, Feldman EL. Insulin resistance as a key link for the increased risk of cognitive impairment in the metabolic syndrome. Experimental & Molecular Medicine. 47: e149. PMID 25766618 DOI: 10.1038/Emm.2015.3  0.317
2015 Lunn JS, Sakowski SA, McGinley LM, Pacut C, Hazel TG, Johe K, Feldman EL. Autocrine production of IGF-I increases stem cell-mediated neuroprotection. Stem Cells (Dayton, Ohio). 33: 1480-9. PMID 25532472 DOI: 10.1002/Stem.1933  0.326
2014 Hamid HS, Mervak CM, Münch AE, Robell NJ, Hayes JM, Porzio MT, Singleton JR, Smith AG, Feldman EL, Lentz SI. Hyperglycemia- and neuropathy-induced changes in mitochondria within sensory nerves. Annals of Clinical and Translational Neurology. 1: 799-812. PMID 25493271 DOI: 10.1002/Acn3.119  0.368
2014 O'Brien PD, Hur J, Hayes JM, Backus C, Sakowski SA, Feldman EL. BTBR ob/ob mice as a novel diabetic neuropathy model: Neurological characterization and gene expression analyses. Neurobiology of Disease. 73: 348-355. PMID 25447227 DOI: 10.1016/J.Nbd.2014.10.015  0.37
2014 Calabek B, Callaghan B, Feldman EL. Therapy for diabetic neuropathy: an overview. Handbook of Clinical Neurology. 126: 317-33. PMID 25410231 DOI: 10.1016/B978-0-444-53480-4.00022-9  0.35
2014 Filla LA, Yuan W, Feldman EL, Li S, Edwards JL. Global metabolomic and isobaric tagging capillary liquid chromatography-tandem mass spectrometry approaches for uncovering pathway dysfunction in diabetic mouse aorta. Journal of Proteome Research. 13: 6121-34. PMID 25368974 DOI: 10.1021/Pr501030E  0.336
2014 Callaghan BC, Feldman EL. Painful diabetic neuropathy: many similarly effective therapies with widely dissimilar costs. Annals of Internal Medicine. 161: 674-5. PMID 25364890 DOI: 10.7326/M14-2157  0.322
2014 Biessels GJ, Bril V, Calcutt NA, Cameron NE, Cotter MA, Dobrowsky R, Feldman EL, Fernyhough P, Jakobsen J, Malik RA, Mizisin AP, Oates PJ, Obrosova IG, Pop-Busui R, Russell JW, et al. Phenotyping animal models of diabetic neuropathy: a consensus statement of the diabetic neuropathy study group of the EASD (Neurodiab). Journal of the Peripheral Nervous System : Jpns. 19: 77-87. PMID 24934510 DOI: 10.1111/Jns5.12072  0.376
2014 O'Brien PD, Sakowski SA, Feldman EL. Mouse models of diabetic neuropathy. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 54: 259-72. PMID 24615439 DOI: 10.1093/Ilar/Ilt052  0.376
2014 O'Brien PD, Hinder LM, Sakowski SA, Feldman EL. ER stress in diabetic peripheral neuropathy: A new therapeutic target. Antioxidants & Redox Signaling. 21: 621-33. PMID 24382087 DOI: 10.1089/Ars.2013.5807  0.372
2014 Hinder LM, Figueroa-Romero C, Pacut C, Hong Y, Vivekanandan-Giri A, Pennathur S, Feldman EL. Long-chain acyl coenzyme A synthetase 1 overexpression in primary cultured Schwann cells prevents long chain fatty acid-induced oxidative stress and mitochondrial dysfunction. Antioxidants & Redox Signaling. 21: 588-600. PMID 23991914 DOI: 10.1089/Ars.2013.5248  0.322
2013 Grote CW, Groover AL, Ryals JM, Geiger PC, Feldman EL, Wright DE. Peripheral nervous system insulin resistance in ob/ob mice. Acta Neuropathologica Communications. 1: 15. PMID 24252636 DOI: 10.1186/2051-5960-1-15  0.345
2013 Jaiswal M, Lauer A, Martin CL, Bell RA, Divers J, Dabelea D, Pettitt DJ, Saydah S, Pihoker C, Standiford DA, Rodriguez BL, Pop-Busui R, Feldman EL. Peripheral neuropathy in adolescents and young adults with type 1 and type 2 diabetes from the SEARCH for Diabetes in Youth follow-up cohort: a pilot study. Diabetes Care. 36: 3903-8. PMID 24144652 DOI: 10.2337/Dc13-1213  0.345
2013 Hur J, Sullivan KA, Callaghan BC, Pop-Busui R, Feldman EL. Identification of factors associated with sural nerve regeneration and degeneration in diabetic neuropathy. Diabetes Care. 36: 4043-9. PMID 24101696 DOI: 10.2337/Dc12-2530  0.351
2013 Vincent AM, Calabek B, Roberts L, Feldman EL. Biology of diabetic neuropathy. Handbook of Clinical Neurology. 115: 591-606. PMID 23931804 DOI: 10.1016/B978-0-444-52902-2.00034-5  0.408
2013 Callaghan B, Feldman E. The metabolic syndrome and neuropathy: therapeutic challenges and opportunities Annals of Neurology. 74: 397-403. PMID 23929529 DOI: 10.1002/Ana.23986  0.319
2013 Pop-Busui R, Stevens MJ, Raffel DM, White EA, Mehta M, Plunkett CD, Brown MB, Feldman EL. Effects of triple antioxidant therapy on measures of cardiovascular autonomic neuropathy and on myocardial blood flow in type 1 diabetes: a randomised controlled trial. Diabetologia. 56: 1835-44. PMID 23740194 DOI: 10.1007/S00125-013-2942-9  0.304
2013 Cheng HT, Dauch JR, Porzio MT, Yanik BM, Hsieh W, Smith AG, Singleton JR, Feldman EL. Increased axonal regeneration and swellings in intraepidermal nerve fibers characterize painful phenotypes of diabetic neuropathy. The Journal of Pain : Official Journal of the American Pain Society. 14: 941-7. PMID 23685187 DOI: 10.1016/J.Jpain.2013.03.005  0.343
2013 Stables CL, Glasser RL, Feldman EL. Diabetic cardiac autonomic neuropathy: insights from animal models. Autonomic Neuroscience : Basic & Clinical. 177: 74-80. PMID 23562143 DOI: 10.1016/J.Autneu.2013.03.001  0.358
2013 Kim B, Backus C, Oh S, Feldman EL. Hyperglycemia-induced tau cleavage in vitro and in vivo: a possible link between diabetes and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 34: 727-39. PMID 23254634 DOI: 10.3233/Jad-121669  0.347
2013 Hinder LM, Vivekanandan-Giri A, McLean LL, Pennathur S, Feldman EL. Decreased glycolytic and tricarboxylic acid cycle intermediates coincide with peripheral nervous system oxidative stress in a murine model of type 2 diabetes. The Journal of Endocrinology. 216: 1-11. PMID 23086140 DOI: 10.1530/Joe-12-0356  0.37
2013 Hinder LM, Vincent AM, Hayes JM, McLean LL, Feldman EL. Apolipoprotein E knockout as the basis for mouse models of dyslipidemia-induced neuropathy. Experimental Neurology. 239: 102-10. PMID 23059459 DOI: 10.1016/J.Expneurol.2012.10.002  0.329
2013 Hur J, Sullivan K, Pop-Busui R, Callaghan B, Feldman E. HbA1c is associated with sural nerve regeneration and degeneration in diabetic neuropathy Journal of the Neurological Sciences. 333: e697-e698. DOI: 10.1016/J.Jns.2013.07.2410  0.355
2012 Sakowski SA, Lunn JS, Busta AS, Oh SS, Zamora-Berridi G, Palmer M, Rosenberg AA, Philip SG, Dowling JJ, Feldman EL. Neuromuscular effects of G93A-SOD1 expression in zebrafish. Molecular Neurodegeneration. 7: 44. PMID 22938571 DOI: 10.1186/1750-1326-7-44  0.312
2012 Callaghan BC, Hur J, Feldman EL. Diabetic neuropathy: one disease or two? Current Opinion in Neurology. 25: 536-41. PMID 22892951 DOI: 10.1097/Wco.0B013E328357A797  0.357
2012 Callaghan BC, Little AA, Feldman EL, Hughes RA. Enhanced glucose control for preventing and treating diabetic neuropathy. The Cochrane Database of Systematic Reviews. 6: CD007543. PMID 22696371 DOI: 10.1002/14651858.Cd007543.Pub2  0.364
2012 Sakowski SA, Feldman EL. Insulin-like growth factors in the peripheral nervous system. Endocrinology and Metabolism Clinics of North America. 41: 375-93, vii. PMID 22682636 DOI: 10.1016/J.Ecl.2012.04.020  0.313
2012 Callaghan BC, Cheng HT, Stables CL, Smith AL, Feldman EL. Diabetic neuropathy: clinical manifestations and current treatments. The Lancet. Neurology. 11: 521-34. PMID 22608666 DOI: 10.1016/S1474-4422(12)70065-0  0.384
2012 Sims-Robinson C, Zhao S, Hur J, Feldman EL. Central nervous system endoplasmic reticulum stress in a murine model of Type 2 diabetes Diabetologia. 55: 2276-2284. PMID 22581041 DOI: 10.1007/S00125-012-2573-6  0.359
2012 Hinder LM, Vincent AM, Burant CF, Pennathur S, Feldman EL. Bioenergetics in diabetic neuropathy: what we need to know. Journal of the Peripheral Nervous System : Jpns. 17: 10-4. PMID 22548617 DOI: 10.1111/J.1529-8027.2012.00389.X  0.393
2012 Oh SS, Sullivan KA, Wilkinson JE, Backus C, Hayes JM, Sakowski SA, Feldman EL. Neurodegeneration and early lethality in superoxide dismutase 2-deficient mice: a comprehensive analysis of the central and peripheral nervous systems. Neuroscience. 212: 201-13. PMID 22516022 DOI: 10.1016/J.Neuroscience.2012.03.026  0.35
2012 Herman WH, Pop-Busui R, Braffett BH, Martin CL, Cleary PA, Albers JW, Feldman EL. Use of the Michigan Neuropathy Screening Instrument as a measure of distal symmetrical peripheral neuropathy in Type 1 diabetes: results from the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications. Diabetic Medicine : a Journal of the British Diabetic Association. 29: 937-44. PMID 22417277 DOI: 10.1111/J.1464-5491.2012.03644.X  0.355
2012 Kim B, Feldman EL. Insulin resistance in the nervous system. Trends in Endocrinology and Metabolism: Tem. 23: 133-41. PMID 22245457 DOI: 10.1016/J.Tem.2011.12.004  0.349
2012 Cheng HT, Dauch JR, Hayes JM, Yanik BM, Feldman EL. Nerve growth factor/p38 signaling increases intraepidermal nerve fiber densities in painful neuropathy of type 2 diabetes. Neurobiology of Disease. 45: 280-7. PMID 21872660 DOI: 10.1016/J.Nbd.2011.08.011  0.364
2012 Hinder L, Buller C, Pennathur S, Feldman E. Bioenergetic Metabolites in the Diabetic Peripheral Nervous System (IN1-1.007) Neurology. 78: IN1-1.007-IN1-1.007. DOI: 10.1212/Wnl.78.1_Meetingabstracts.In1-1.007  0.383
2012 Cheng H, Dauch J, Porzio M, Yanik B, Hsieh W, Smith A, Singleton J, Feldman E. Useful Biomarkers for the Diagnosis of Painful Diabetic Neuropathy (IN1-1.004) Neurology. 78: IN1-1.004-IN1-1.004. DOI: 10.1212/Wnl.78.1_Meetingabstracts.In1-1.004  0.314
2012 Vincent AM, McLean LL, Pande M, Oh SS, Feldman EL. LOX-1-mediated injury in sensory neurons in type 2 diabetes International Journal of Diabetes and Metabolism. 20: 59-63. DOI: 10.1159/000497727  0.37
2011 Hur J, Sullivan KA, Pande M, Hong Y, Sima AA, Jagadish HV, Kretzler M, Feldman EL. The identification of gene expression profiles associated with progression of human diabetic neuropathy. Brain : a Journal of Neurology. 134: 3222-35. PMID 21926103 DOI: 10.1093/Brain/Awr228  0.385
2011 Vincent AM, Callaghan BC, Smith AL, Feldman EL. Diabetic neuropathy: cellular mechanisms as therapeutic targets. Nature Reviews. Neurology. 7: 573-83. PMID 21912405 DOI: 10.1038/Nrneurol.2011.137  0.401
2011 Kim B, McLean LL, Philip SS, Feldman EL. Hyperinsulinemia induces insulin resistance in dorsal root ganglion neurons. Endocrinology. 152: 3638-47. PMID 21810948 DOI: 10.1210/En.2011-0029  0.337
2011 Dyck PJ, Albers JW, Andersen H, Arezzo JC, Biessels GJ, Bril V, Feldman EL, Litchy WJ, O'Brien PC, Russell JW. Diabetic polyneuropathies: update on research definition, diagnostic criteria and estimation of severity. Diabetes/Metabolism Research and Reviews. 27: 620-8. PMID 21695763 DOI: 10.1002/Dmrr.1226  0.361
2011 Pande M, Hur J, Hong Y, Backus C, Hayes JM, Oh SS, Kretzler M, Feldman EL. Transcriptional profiling of diabetic neuropathy in the BKS db/db mouse: a model of type 2 diabetes. Diabetes. 60: 1981-9. PMID 21617178 DOI: 10.2337/Db10-1541  0.376
2011 Callaghan BC, Feldman E, Liu J, Kerber K, Pop-Busui R, Moffet H, Karter AJ. Triglycerides and amputation risk in patients with diabetes: ten-year follow-up in the DISTANCE study. Diabetes Care. 34: 635-40. PMID 21285390 DOI: 10.2337/Dc10-0878  0.324
2011 Kim B, Sullivan KA, Backus C, Feldman EL. Cortical neurons develop insulin resistance and blunted Akt signaling: a potential mechanism contributing to enhanced ischemic injury in diabetes. Antioxidants & Redox Signaling. 14: 1829-39. PMID 21194385 DOI: 10.1089/Ars.2010.3816  0.332
2011 Schuyler AD, Carlson HA, Feldman EL. Computational methods for identifying a layered allosteric regulatory mechanism for ALS-causing mutations of Cu-Zn superoxide dismutase 1. Proteins. 79: 417-27. PMID 21104697 DOI: 10.1002/Prot.22892  0.686
2010 Hur J, Sullivan KA, Schuyler AD, Hong Y, Pande M, States DJ, Jagadish HV, Feldman EL. Literature-based discovery of diabetes- and ROS-related targets. Bmc Medical Genomics. 3: 49. PMID 20979611 DOI: 10.1186/1755-8794-3-49  0.724
2010 Sims-Robinson C, Kim B, Rosko A, Feldman EL. How does diabetes accelerate Alzheimer disease pathology? Nature Reviews Neurology. 6: 551-559. PMID 20842183 DOI: 10.1038/Nrneurol.2010.130  0.362
2010 Martin CL, Waberski BH, Pop-Busui R, Cleary PA, Catton S, Albers JW, Feldman EL, Herman WH. Vibration perception threshold as a measure of distal symmetrical peripheral neuropathy in type 1 diabetes: results from the DCCT/EDIC study. Diabetes Care. 33: 2635-41. PMID 20833868 DOI: 10.2337/Dc10-0616  0.342
2010 Oh SS, Hayes JM, Sims-Robinson C, Sullivan KA, Feldman EL. The effects of anesthesia on measures of nerve conduction velocity in male C57Bl6/J mice. Neuroscience Letters. 483: 127-31. PMID 20691755 DOI: 10.1016/J.Neulet.2010.07.076  0.305
2010 Cheng HT, Dauch JR, Oh SS, Hayes JM, Hong Y, Feldman EL. p38 mediates mechanical allodynia in a mouse model of type 2 diabetes. Molecular Pain. 6: 28. PMID 20482876 DOI: 10.1186/1744-8069-6-28  0.354
2010 Kakoki M, Sullivan KA, Backus C, Hayes JM, Oh SS, Hua K, Gasim AM, Tomita H, Grant R, Nossov SB, Kim HS, Jennette JC, Feldman EL, Smithies O. Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 10190-5. PMID 20479236 DOI: 10.1073/Pnas.1005144107  0.366
2010 Vincent AM, Edwards JL, McLean LL, Hong Y, Cerri F, Lopez I, Quattrini A, Feldman EL. Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy. Acta Neuropathologica. 120: 477-89. PMID 20473509 DOI: 10.1007/S00401-010-0697-7  0.343
2010 Pop-Busui R, Herman WH, Feldman EL, Low PA, Martin CL, Cleary PA, Waberski BH, Lachin JM, Albers JW. DCCT and EDIC studies in type 1 diabetes: lessons for diabetic neuropathy regarding metabolic memory and natural history. Current Diabetes Reports. 10: 276-82. PMID 20464532 DOI: 10.1007/S11892-010-0120-8  0.368
2010 Lunn JS, Pacut C, Backus C, Hong Y, Johe K, Hefferan M, Marsala M, Feldman EL. The pleotrophic effects of insulin-like growth factor-I on human spinal cord neural progenitor cells. Stem Cells and Development. 19: 1983-93. PMID 20406098 DOI: 10.1089/Scd.2010.0003  0.318
2010 Albers JW, Herman WH, Pop-Busui R, Feldman EL, Martin CL, Cleary PA, Waberski BH, Lachin JM. Effect of prior intensive insulin treatment during the Diabetes Control and Complications Trial (DCCT) on peripheral neuropathy in type 1 diabetes during the Epidemiology of Diabetes Interventions and Complications (EDIC) Study. Diabetes Care. 33: 1090-6. PMID 20150297 DOI: 10.2337/Dc09-1941  0.367
2010 Pop-Busui R, Roberts L, Pennathur S, Kretzler M, Brosius FC, Feldman EL. The management of diabetic neuropathy in CKD. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 55: 365-85. PMID 20042258 DOI: 10.1053/J.Ajkd.2009.10.050  0.314
2010 Edwards JL, Quattrini A, Lentz SI, Figueroa-Romero C, Cerri F, Backus C, Hong Y, Feldman EL. Diabetes regulates mitochondrial biogenesis and fission in mouse neurons. Diabetologia. 53: 160-9. PMID 19847394 DOI: 10.1007/S00125-009-1553-Y  0.325
2010 Cheng H, Dauch J, Hayes J, Hong Y, Feldman E. P38 mediates mechanical allodynia in a mouse model of type 2 diabetes The Journal of Pain. 11: S25. DOI: 10.1016/J.Jpain.2010.01.107  0.33
2009 Vincent AM, Hinder LM, Pop-Busui R, Feldman EL. Hyperlipidemia: a new therapeutic target for diabetic neuropathy. Journal of the Peripheral Nervous System : Jpns. 14: 257-67. PMID 20021567 DOI: 10.1111/J.1529-8027.2009.00237.X  0.392
2009 Kim B, Backus C, Oh S, Hayes JM, Feldman EL. Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes. Endocrinology. 150: 5294-301. PMID 19819959 DOI: 10.1210/En.2009-0695  0.341
2009 Cheng HT, Dauch JR, Hayes JM, Hong Y, Feldman EL. Nerve growth factor mediates mechanical allodynia in a mouse model of type 2 diabetes. Journal of Neuropathology and Experimental Neurology. 68: 1229-43. PMID 19816194 DOI: 10.1097/Nen.0B013E3181Bef710  0.355
2009 Lunn JS, Sakowski SA, Kim B, Rosenberg AA, Feldman EL. Vascular endothelial growth factor prevents G93A-SOD1-induced motor neuron degeneration. Developmental Neurobiology. 69: 871-84. PMID 19672955 DOI: 10.1002/Dneu.20747  0.31
2009 Vincent AM, Hayes JM, McLean LL, Vivekanandan-Giri A, Pennathur S, Feldman EL. Dyslipidemia-induced neuropathy in mice: the role of oxLDL/LOX-1. Diabetes. 58: 2376-85. PMID 19592619 DOI: 10.2337/Db09-0047  0.383
2009 Pop-Busui R, Low PA, Waberski BH, Martin CL, Albers JW, Feldman EL, Sommer C, Cleary PA, Lachin JM, Herman WH. Effects of prior intensive insulin therapy on cardiac autonomic nervous system function in type 1 diabetes mellitus: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study (DCCT/EDIC). Circulation. 119: 2886-93. PMID 19470886 DOI: 10.1161/Circulationaha.108.837369  0.319
2009 Wiggin TD, Sullivan KA, Pop-Busui R, Amato A, Sima AA, Feldman EL. Elevated triglycerides correlate with progression of diabetic neuropathy. Diabetes. 58: 1634-40. PMID 19411614 DOI: 10.2337/Db08-1771  0.356
2009 Schuyler AD, Carlson HA, Feldman EL. Computational methods for predicting sites of functionally important dynamics. The Journal of Physical Chemistry. B. 113: 6613-22. PMID 19378962 DOI: 10.1016/J.Bpj.2008.12.3643  0.677
2009 Lunn JS, Hefferan MP, Marsala M, Feldman EL. Stem cells: Comprehensive treatments for amyotrophic lateral sclerosis in conjunction with growth factor delivery Growth Factors. 27: 133-140. PMID 19294549 DOI: 10.1080/08977190902814855  0.329
2009 Hur J, Schuyler AD, States DJ, Feldman EL. SciMiner: web-based literature mining tool for target identification and functional enrichment analysis. Bioinformatics (Oxford, England). 25: 838-40. PMID 19188191 DOI: 10.1093/Bioinformatics/Btp049  0.682
2009 Franz CK, Federici T, Yang J, Backus C, Oh SS, Teng Q, Carlton E, Bishop KM, Gasmi M, Bartus RT, Feldman EL, Boulis NM. Intraspinal cord delivery of IGF-I mediated by adeno-associated virus 2 is neuroprotective in a rat model of familial ALS. Neurobiology of Disease. 33: 473-81. PMID 19135533 DOI: 10.1016/J.Nbd.2008.12.003  0.302
2009 Vincent AM, Kato K, McLean LL, Soules ME, Feldman EL. Sensory neurons and schwann cells respond to oxidative stress by increasing antioxidant defense mechanisms Antioxidants and Redox Signaling. 11: 425-438. PMID 19072199 DOI: 10.1089/Ars.2008.2235  0.334
2009 Sakowski SA, Schuyler AD, Feldman EL. Insulin-like growth factor-I for the treatment of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 10: 63-73. PMID 18608100 DOI: 10.1080/17482960802160370  0.718
2009 Kern TS, Berkowitz BA, Feldman EL. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) meeting summary: Advances toward measuring diabetic retinopathy and neuropathy: from the bench to the clinic and back again (April 4-5, 2007, Baltimore, Maryland). Journal of Diabetes and Its Complications. 23: 219-23. PMID 18413183 DOI: 10.1016/J.Jdiacomp.2007.11.001  0.359
2008 Singleton JR, Bixby B, Russell JW, Feldman EL, Peltier A, Goldstein J, Howard J, Smith AG. The Utah Early Neuropathy Scale: a sensitive clinical scale for early sensory predominant neuropathy. Journal of the Peripheral Nervous System : Jpns. 13: 218-27. PMID 18844788 DOI: 10.1111/J.1529-8027.2008.00180.X  0.303
2008 Sullivan KA, Kim B, Feldman EL. Minireview: Insulin-like growth factors in the peripheral nervous system Endocrinology. 149: 5963-5971. PMID 18719018 DOI: 10.1210/En.2008-1020  0.337
2008 Figueroa-Romero C, Sadidi M, Feldman EL. Mechanisms of disease: the oxidative stress theory of diabetic neuropathy. Reviews in Endocrine & Metabolic Disorders. 9: 301-14. PMID 18709457 DOI: 10.1007/S11154-008-9104-2  0.377
2008 Zhang H, Saha J, Byun J, Schin M, Lorenz M, Kennedy RT, Kretzler M, Feldman EL, Pennathur S, Brosius FC. Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy. American Journal of Physiology. Renal Physiology. 295: F1071-81. PMID 18667486 DOI: 10.1152/Ajprenal.90208.2008  0.364
2008 Edwards JL, Vincent AM, Cheng HT, Feldman EL. Diabetic neuropathy: mechanisms to management. Pharmacology & Therapeutics. 120: 1-34. PMID 18616962 DOI: 10.1016/J.Pharmthera.2008.05.005  0.377
2008 Wiggin TD, Kretzler M, Pennathur S, Sullivan KA, Brosius FC, Feldman EL. Rosiglitazone treatment reduces diabetic neuropathy in streptozotocin-treated DBA/2J mice. Endocrinology. 149: 4928-37. PMID 18583417 DOI: 10.1210/En.2008-0869  0.364
2008 Qian Y, Feldman E, Pennathur S, Kretzler M, Brosius FC. From fibrosis to sclerosis: mechanisms of glomerulosclerosis in diabetic nephropathy. Diabetes. 57: 1439-45. PMID 18511444 DOI: 10.2337/Db08-0061  0.375
2008 Russell JW, Berent-Spillson A, Vincent AM, Freimann CL, Sullivan KA, Feldman EL. Oxidative injury and neuropathy in diabetes and impaired glucose tolerance. Neurobiology of Disease. 30: 420-9. PMID 18424057 DOI: 10.1016/J.Nbd.2008.02.013  0.372
2008 Muller KA, Ryals JM, Feldman EL, Wright DE. Abnormal muscle spindle innervation and large-fiber neuropathy in diabetic mice. Diabetes. 57: 1693-701. PMID 18362211 DOI: 10.2337/Db08-0022  0.348
2008 Vincent AM, Edwards JL, Sadidi M, Feldman EL. The antioxidant response as a drug target in diabetic neuropathy. Current Drug Targets. 9: 94-100. PMID 18220717 DOI: 10.2174/138945008783431754  0.322
2008 Sullivan KA, Lentz SI, Roberts JL, Feldman EL. Criteria for creating and assessing mouse models of diabetic neuropathy. Current Drug Targets. 9: 3-13. PMID 18220709 DOI: 10.2174/138945008783431763  0.37
2008 Vincent AM, Sakowski SA, Schuyler A, Feldman EL. Strategic approaches to developing drug treatments for ALS. Drug Discovery Today. 13: 67-72. PMID 18190866 DOI: 10.1016/J.Drudis.2007.10.011  0.705
2008 Vincent AM, Feldman EL. Can drug screening lead to candidate therapies for testing in diabetic neuropathy? Antioxidants and Redox Signaling. 10: 387-393. PMID 17961065 DOI: 10.1089/Ars.2007.1815  0.329
2008 Cheng H, Hayes J, Hong Y, Feldman E. (106) Upregulation of nerve growth factor signaling in painful neuropathy of type 2 diabetes The Journal of Pain. 9: 2. DOI: 10.1016/J.Jpain.2008.01.024  0.341
2007 Vincent AM, Russell JW, Sullivan KA, Backus C, Hayes JM, McLean LL, Feldman EL. SOD2 protects neurons from injury in cell culture and animal models of diabetic neuropathy. Experimental Neurology. 208: 216-27. PMID 17927981 DOI: 10.1016/J.Expneurol.2007.07.017  0.36
2007 Sullivan KA, Hayes JM, Wiggin TD, Backus C, Su Oh S, Lentz SI, Brosius F, Feldman EL. Mouse models of diabetic neuropathy. Neurobiology of Disease. 28: 276-85. PMID 17804249 DOI: 10.1016/J.Nbd.2007.07.022  0.324
2007 Cornblath DR, Vinik A, Feldman E, Freeman R, Boulton AJM. Surgical decompression for diabetic sensorimotor polyneuropathy. Diabetes Care. 30: 421-422. PMID 17259523 DOI: 10.2337/Dc06-2324  0.369
2007 Vincent AM, Perrone L, Sullivan KA, Backus C, Sastry AM, Lastoskie C, Feldman EL. Receptor for advanced glycation end products activation injures primary sensory neurons via oxidative stress. Endocrinology. 148: 548-58. PMID 17095586 DOI: 10.1210/En.2006-0073  0.357
2006 Leinninger GM, Edwards JL, Lipshaw MJ, Feldman EL. Mechanisms of disease: mitochondria as new therapeutic targets in diabetic neuropathy. Nature Clinical Practice. Neurology. 2: 620-8. PMID 17057749 DOI: 10.1038/Ncpneuro0320  0.688
2006 Smith AG, Russell J, Feldman EL, Goldstein J, Peltier A, Smith S, Hamwi J, Pollari D, Bixby B, Howard J, Singleton JR. Lifestyle intervention for pre-diabetic neuropathy Diabetes Care. 29: 1294-1299. PMID 16732011 DOI: 10.2337/Dc06-0224  0.341
2006 Leinninger GM, Backus C, Sastry AM, Yi YB, Wang CW, Feldman EL. Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1. Neurobiology of Disease. 23: 11-22. PMID 16684605 DOI: 10.1016/J.Nbd.2006.01.017  0.673
2006 Martin CL, Albers J, Herman WH, Cleary P, Waberski B, Greene DA, Stevens MJ, Feldman EL. Neuropathy among the diabetes control and complications trial cohort 8 years after trial completion. Diabetes Care. 29: 340-4. PMID 16443884 DOI: 10.2337/Diacare.29.02.06.Dc05-1549  0.329
2005 Vincent AM, Stevens MJ, Backus C, McLean LL, Feldman EL. Cell culture modeling to test therapies against hyperglycemia-mediated oxidative stress and injury. Antioxidants & Redox Signaling. 7: 1494-506. PMID 16356113 DOI: 10.1089/Ars.2005.7.1494  0.335
2005 Sullivan KA, Feldman EL. New developments in diabetic neuropathy Current Opinion in Neurology. 18: 586-590. PMID 16155445 DOI: 10.1097/01.Wco.0000178825.56414.52  0.398
2005 Schwab TS, Madison BB, Grauman AR, Feldman EL. Insulin-like growth factor-I induces the phosphorylation and nuclear exclusion of forkhead transcription factors in human neuroblastoma cells. Apoptosis : An International Journal On Programmed Cell Death. 10: 831-40. PMID 16133873 DOI: 10.1007/S10495-005-0429-Y  0.301
2005 Russo VC, Gluckman PD, Feldman EL, Werther GA. The insulin-like growth factor system and its pleiotropic functions in brain Endocrine Reviews. 26: 916-943. PMID 16131630 DOI: 10.1210/Er.2004-0024  0.318
2005 Vincent AM, Backus C, Taubman AA, Feldman EL. Identification of candidate drugs for the treatment of ALS Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. 6: 29-36. PMID 16036423 DOI: 10.1080/14660820510026171  0.303
2005 Leinninger GM, Feldman EL. Insulin-like growth factors in the treatment of neurological disease. Endocrine Development. 9: 135-59. PMID 15879695 DOI: 10.1159/000085763  0.676
2005 Boulton AJ, Vinik AI, Arezzo JC, Bril V, Feldman EL, Freeman R, Malik RA, Maser RE, Sosenko JM, Ziegler D. Diabetic neuropathies: a statement by the American Diabetes Association. Diabetes Care. 28: 956-62. PMID 15793206 DOI: 10.2337/Diacare.28.4.956  0.377
2005 Meyer G, Kim B, Van Golen C, Feldman EL. Cofilin activity during insulin-like growth factor I-stimulated neuroblastoma cell motility Cellular and Molecular Life Sciences. 62: 461-470. PMID 15719172 DOI: 10.1007/S00018-004-4456-6  0.56
2005 Vincent AM, McLean LL, Backus C, Feldman EL. Short-term hyperglycemia produces oxidative damage and apoptosis in neurons Faseb Journal. 19: 638-640. PMID 15677696 DOI: 10.1096/Fj.04-2513Fje  0.345
2005 Meyer A, van Golen CM, Boyanapalli M, Kim B, Soules ME, Feldman EL. Integrin-linked kinase complexes with caveolin-1 in human neuroblastoma cells. Biochemistry. 44: 932-8. PMID 15654749 DOI: 10.1021/Bi048619R  0.552
2005 Singleton JR, Smith AG, Russell J, Feldman EL. Polyneuropathy with impaired glucose tolerance: Implication for diagnosis and therapy Current Treatment Options in Neurology. 7: 33-42. DOI: 10.1007/S11940-005-0004-4  0.312
2004 Vincent AM, Feldman EL, Song DK, Jung V, Schild A, Zhang W, Imperiale MJ, Boulis NM. Adeno-associated viral-mediated insulin-like growth factor delivery protects motor neurons in vitro. Neuromolecular Medicine. 6: 79-85. PMID 15970625 DOI: 10.1385/Nmm:6:2-3:079  0.33
2004 Leinninger GM, Backus C, Uhler MD, Lentz SI, Feldman EL. Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1544-6. PMID 15319368 DOI: 10.1096/Fj.04-1581Fje  0.67
2004 Vincent AM, Russell JW, Low P, Feldman EL. Oxidative stress in the pathogenesis of diabetic neuropathy. Endocrine Reviews. 25: 612-28. PMID 15294884 DOI: 10.1210/Er.2003-0019  0.35
2004 Meyer A, van Golen CM, Kim B, van Golen KL, Feldman EL. Integrin expression regulates neuroblastoma attachment and migration. Neoplasia (New York, N.Y.). 6: 332-42. PMID 15256055 DOI: 10.1593/Neo.03445  0.559
2004 Vincent AM, Feldman EL. New insights into the mechanisms of diabetic neuropathy Reviews in Endocrine and Metabolic Disorders. 5: 227-236. PMID 15211094 DOI: 10.1023/B:Remd.0000032411.11422.E0  0.349
2004 Vincent AM, Mobley BC, Hiller A, Feldman EL. IGF-I prevents glutamate-induced motor neuron programmed cell death Neurobiology of Disease. 16: 407-416. PMID 15193297 DOI: 10.1016/J.Nbd.2004.03.001  0.322
2004 Layton BE, Sastry AM, Wang H, Sullivan KA, Feldman EL, Komorowski TE, Philbert MA. Differences between collagen morphologies, properties and distribution in diabetic and normal biobreeding and Sprague-Dawley rat sciatic nerves. Journal of Biomechanics. 37: 879-88. PMID 15111075 DOI: 10.1016/J.Jbiomech.2003.11.008  0.358
2004 Leinninger GM, Russell JW, van Golen CM, Berent A, Feldman EL. Insulin-like growth factor-I regulates glucose-induced mitochondrial depolarization and apoptosis in human neuroblastoma. Cell Death and Differentiation. 11: 885-96. PMID 15105834 DOI: 10.1038/Sj.Cdd.4401429  0.657
2004 Leinninger GM, Vincent AM, Feldman EL. The role of growth factors in diabetic peripheral neuropathy. Journal of the Peripheral Nervous System : Jpns. 9: 26-53. PMID 14871451 DOI: 10.1111/J.1085-9489.2004.09105.X  0.694
2003 Singleton JR, Smith AG, Russell JW, Feldman EL. Microvascular complications of impaired glucose tolerance. Diabetes. 52: 2867-73. PMID 14633845 DOI: 10.2337/Diabetes.52.12.2867  0.334
2003 Feldman EL. Oxidative stress and diabetic neuropathy: A new understanding of an old problem Journal of Clinical Investigation. 111: 431-433. PMID 12588877 DOI: 10.1172/Jci17862  0.367
2002 Meyer G, Feldman EL. Signaling mechanisms that regulate actin-based motility processes in the nervous system Journal of Neurochemistry. 83: 490-503. PMID 12390511 DOI: 10.1046/J.1471-4159.2002.01185.X  0.543
2002 Simmons Z, Feldman EL. Update on diabetic neuropathy Current Opinion in Neurology. 15: 595-603. PMID 12352003 DOI: 10.1097/00019052-200210000-00010  0.394
2002 Kim B, Feldman EL. Insulin-like growth factor I prevents mannitol-induced degradation of focal adhesion kinase and Akt Journal of Biological Chemistry. 277: 27393-27400. PMID 12011046 DOI: 10.1074/Jbc.M201963200  0.307
2001 Meyer GE, Shelden E, Kim B, Feldman EL. Insulin-like growth factor I stimulates motility in human neuroblastoma cells. Oncogene. 20: 7542-50. PMID 11709726 DOI: 10.1038/Sj.Onc.1204927  0.572
2001 Apfel SC, Asbury AK, Bril V, Burns TM, Campbell JN, Chalk CH, Dyck PJ, Dyck PJ, Feldman EL, Fields HL, Grant IA, Griffin JW, Klein CJ, Lindblom U, Litchy WJ, et al. Positive neuropathic sensory symptoms as endpoints in diabetic neuropathy trials. Journal of the Neurological Sciences. 189: 3-5. PMID 11596565 DOI: 10.1016/S0022-510X(01)00584-6  0.316
2001 Robinson Singleton J, Feldman EL. Insulin-like growth factor-I in muscle metabolism and myotherapies Neurobiology of Disease. 8: 541-554. PMID 11493020 DOI: 10.1006/Nbdi.2001.0416  0.311
2001 Delaney CL, Russell JW, Cheng HL, Feldman EL. Insulin-like growth factor-I and over-expression of Bcl-xL prevent glucose-mediated apoptosis in Schwann cells. Journal of Neuropathology and Experimental Neurology. 60: 147-60. PMID 11273003 DOI: 10.1093/Jnen/60.2.147  0.375
2001 Cheng HL, Steinway ML, Xin X, Feldman EL. Insulin-like growth factor-I and Bcl-XL inhibit c-jun N-terminal kinase activation and rescue Schwann cells from apoptosis Journal of Neurochemistry. 76: 935-943. PMID 11158266 DOI: 10.1046/J.1471-4159.2001.00110.X  0.302
2000 Van Golen CM, Feldman EL. Insulin-like growth factor I is the key growth factor in serum that protects neuroblastoma cells from hyperosmotic-induced apoptosis Journal of Cellular Physiology. 182: 24-32. PMID 10567913 DOI: 10.1002/(Sici)1097-4652(200001)182:1<24::Aid-Jcp3>3.0.Co;2-6  0.305
2000 Delaney CL, Feldman EL. Review ■ : Insulin-like Growth Factor-I and Apoptosis in Glial Cell Biology The Neuroscientist. 6: 39-47. DOI: 10.1177/107385840000600112  0.333
2000 Pop‐Busui R, Sullivan K, Russel J, Feldman E, Stockert C, Larkin D, Greene D, Stevens M. Taurine Replacement Prevents Apoptosis In Experimental Diabetic Neuropathy Journal of the Peripheral Nervous System. 5: 179-180. DOI: 10.1046/J.1529-8027.2000Abstracts-37.X  0.338
1999 Feldman EL, Russell JW, Sullivan KA, Golovoy D. New insights into the pathogenesis of diabetic neuropathy. Current Opinion in Neurology. 12: 553-63. PMID 10590892 DOI: 10.1097/00019052-199910000-00009  0.346
1999 Delaney CL, Cheng HL, Feldman EL. Insulin-like growth factor-I prevents caspasemediated apoptosis in Schwann cells Journal of Neurobiology. 41: 540-548. PMID 10590177 DOI: 10.1002/(Sici)1097-4695(199912)41:4<540::Aid-Neu9>3.0.Co;2-P  0.316
1999 Russell JW, Sullivan KA, Windebank AJ, Herrmann DN, Feldman EL. Neurons undergo apoptosis in animal and cell culture models of diabetes. Neurobiology of Disease. 6: 347-63. PMID 10527803 DOI: 10.1006/Nbdi.1999.0254  0.384
1999 Cheng HL, Shy M, Feldman EL. Regulation of insulin-like growth factor-binding protein-5 expression during schwann cell differentiation Endocrinology. 140: 4478-4485. PMID 10499501 DOI: 10.1210/Endo.140.10.7051  0.302
1999 Greene DA, Stevens MJ, Feldman EL. Diabetic neuropathy: Scope of the syndrome American Journal of Medicine. 107. PMID 10484039 DOI: 10.1016/S0002-9343(99)00007-8  0.394
1999 Greene DA, Stevens MJ, Obrosova I, Feldman EL. Glucose-induced oxidative stress and programmed cell death in diabetic neuropathy European Journal of Pharmacology. 375: 217-223. PMID 10443578 DOI: 10.1016/S0014-2999(99)00356-8  0.385
1999 Anlar B, Sullivan KA, Feldman EL. Insulin-like growth factor-I and central nervous system development Hormone and Metabolic Research. 31: 120-125. PMID 10226791 DOI: 10.1055/S-2007-978708  0.324
1999 Russell JW, Feldman EL. Insulin-like growth factor-I prevents apoptosis in sympathetic neurons exposed to high glucose. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 31: 90-6. PMID 10226787 DOI: 10.1055/S-2007-978704  0.378
1999 Hogikyan RV, Wald JJ, Feldman EL, Greene DA, Halter JB, Supiano MA. Acute effects of adrenergic-mediated ischemia on nerve conduction in subjects with type 2 diabetes. Metabolism: Clinical and Experimental. 48: 495-500. PMID 10206444 DOI: 10.1016/S0026-0495(99)90110-5  0.34
1998 Russell JW, Windebank AJ, Schenone A, Feldman EL. Insulin-like growth factor-I prevents apoptosis in neurons after nerve growth factor withdrawal. Journal of Neurobiology. 36: 455-67. PMID 9740019 DOI: 10.1002/(Sici)1097-4695(19980915)36:4<455::Aid-Neu1>3.0.Co;2-V  0.333
1998 Stevens MJ, Dayanikli F, Raffel DM, Allman KC, Sandford T, Feldman EL, Wieland DM, Corbett J, Schwaiger M. Scintigraphic assessment of regionalized defects in myocardial sympathetic innervation and blood flow regulation in diabetic patients with autonomic neuropathy. Journal of the American College of Cardiology. 31: 1575-84. PMID 9626837 DOI: 10.1016/S0735-1097(98)00128-4  0.3
1997 Feldman EL, Sullivan KA, Kim B, Russell JW. Insulin-like growth factors regulate neuronal differentiation and survival. Neurobiology of Disease. 4: 201-14. PMID 9361296 DOI: 10.1006/Nbdi.1997.0156  0.312
1997 Matthews CC, Odeh HM, Feldman EL. Insulin-like growth factor-I is an osmoprotectant in human neuroblastoma cells. Neuroscience. 79: 525-34. PMID 9200735 DOI: 10.1016/S0306-4522(96)00611-2  0.325
1997 Fedele D, Comi G, Coscelli C, Cucinotta D, Feldman EL, Ghirlanda G, Greene DA, Negrin P, Santeusanio F. A multicenter study on the prevalence of diabetic neuropathy in Italy Diabetes Care. 20: 836-843. PMID 9135952 DOI: 10.2337/Diacare.20.5.836  0.361
1997 Cheng HL, Feldman EL. Insulin-like growth Factor-I (IGF-I) and IGF binding protein-5 in Schwann cell differentiation Journal of Cellular Physiology. 171: 161-167. PMID 9130463 DOI: 10.1002/(Sici)1097-4652(199705)171:2<161::Aid-Jcp6>3.0.Co;2-M  0.311
1997 Sullivan KA, Bhumsoo K, Buzdon M, Feldman EL. Suramin disrupts insulin-like growth factor-II (IGF-II) mediated autocrine growth in human SH-SY5Y neuroblastoma cells Brain Research. 744: 199-206. PMID 9027379 DOI: 10.1016/S0006-8993(96)01078-5  0.302
1997 Leventhal PS, Feldman EL. Insulin-like growth factors as regulators of cell motility: Signaling mechanisms Trends in Endocrinology and Metabolism. 8: 1-6. DOI: 10.1016/S1043-2760(96)00202-0  0.308
1997 Greene DA, Stevens MJ, Feldman EL, Thomas TP. The DCCT, metabolism and diabetic neuropathy: Perspectives for the fourth international symposium on diabetic neuropathy Neuroscience Research Communications. 21: 1-4. DOI: 10.1002/(Sici)1520-6769(199707)21:1<1::Aid-Nrc201>3.0.Co;2-L  0.347
1996 Singleton JR, Dixit VM, Feldman EL. Type I insulin-like growth factor receptor activation regulates apoptotic proteins Journal of Biological Chemistry. 271: 31791-31794. PMID 8943217 DOI: 10.1074/Jbc.271.50.31791  0.308
1996 Cheng HL, Sullivan KA, Feldman EL. Immunohistochemical localization of insulin-like growth factor binding protein-5 in the developing rat nervous system Developmental Brain Research. 92: 211-218. PMID 8738128 DOI: 10.1016/0165-3806(96)00016-8  0.324
1996 Stevens MJ, Lattimer SA, Feldman EL, Helton ED, Millington DS, Sima AA, Greene DA. Acetyl-L-carnitine deficiency as a cause of altered nerve myo-inositol content, Na,K-ATPase activity, and motor conduction velocity in the streptozotocin-diabetic rat. Metabolism: Clinical and Experimental. 45: 865-72. PMID 8692023 DOI: 10.1016/S0026-0495(96)90161-4  0.353
1996 Cheng HL, Randolph A, Yee D, Delafontaine P, Tennekoon G, Feldman EL. Characterization of insulin-like growth factor-I and its receptor and binding proteins in transected nerves and cultured Schwann cells. Journal of Neurochemistry. 66: 525-36. PMID 8592122 DOI: 10.1046/J.1471-4159.1996.66020525.X  0.313
1996 Matthews CC, Feldman EL. Insulin-like growth factor I rescues SH-SY5Y human neuroblastoma cells from hyperosmotic induced programmed cell death. Journal of Cellular Physiology. 166: 323-31. PMID 8591992 DOI: 10.1002/(Sici)1097-4652(199602)166:2<323::Aid-Jcp10>3.0.Co;2-C  0.312
1995 Stevens MJ, Feldman EL, Greene DA. The aetiology of diabetic neuropathy: The combined roles of metabolic and vascular defects Diabetic Medicine. 12: 566-579. PMID 7554777 DOI: 10.1111/J.1464-5491.1995.Tb00544.X  0.339
1994 Stevens MJ, Dananberg J, Feldman EL, Lattimer SA, Kamijo M, Thomas TP, Shindo H, Sima AA, Greene DA. The linked roles of nitric oxide, aldose reductase and, (Na+,K+)-ATPase in the slowing of nerve conduction in the streptozotocin diabetic rat. The Journal of Clinical Investigation. 94: 853-9. PMID 8040341 DOI: 10.1172/Jci117406  0.327
1994 Feldman EL, Stevens MJ. Clinical Testing in Diabetic Peripheral Neuropathy Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 21: S3-S7. PMID 7874610 DOI: 10.1017/S0317167100040671  0.361
1994 Feldman EL, Stevens MJ, Thomas PK, Brown MB, Canal N, Greene DA. A practical two-step quantitative clinical and electrophysiological assessment for the diagnosis and staging of diabetic neuropathy. Diabetes Care. 17: 1281-9. PMID 7821168 DOI: 10.2337/Diacare.17.11.1281  0.343
1993 Sumantran VN, Feldman EL. Insulin-like growth factor I regulates c-myc and GAP-43 messenger ribonucleic acid expression in SH-SY5Y human neuroblastoma cells Endocrinology. 132: 2017-2023. PMID 8477653 DOI: 10.1210/Endo.132.5.8477653  0.314
1993 Simmons Z, Bromberg MB, Feldman EL, Blaivas M. Polyneuropathy associated with IgA monoclonal gammopathy of undetermined significance. Muscle & Nerve. 16: 77-83. PMID 8380902 DOI: 10.1002/Mus.880160113  0.31
1993 Greene DA, Sima AA, Stevens MJ, Feldman EL, Killen PD, Henry DN, Thomas T, Dananberg J, Lattimer SA. Aldose reductase inhibitors: an approach to the treatment of diabetic nerve damage. Diabetes/Metabolism Reviews. 9: 189-217. PMID 8187607 DOI: 10.1002/Dmr.5610090304  0.34
1992 Greene DA, Sima AA, Stevens MJ, Feldman EL, Lattimer SA. Complications: neuropathy, pathogenetic considerations. Diabetes Care. 15: 1902-25. PMID 1464245 DOI: 10.2337/Diacare.15.12.1902  0.373
1992 Martin DM, Yee D, Carlson RO, Feldman EL. Gene expression of the insulin-like growth factors and their receptors in human neuroblastoma cell lines Molecular Brain Research. 15: 241-246. PMID 1331680 DOI: 10.1016/0169-328X(92)90114-Q  0.307
1992 Greene D, Nakamura J, Thomas T, Lattimer-Greene S, Henry D, Feldman E, Stevens M, Killen P, Sima A. The myo-inositol (MI) depletion hypothesis of diabetic complications Experimental Eye Research. 55: 166. DOI: 10.1016/0014-4835(92)90778-Q  0.335
1990 Griffin JW, Cornblath DR, Alexander E, Campbell J, Low PA, Bird S, Feldman EL. Ataxic sensory neuropathy and dorsal root ganglionitis associated with Sjögren's syndrome Annals of Neurology. 27: 304-315. PMID 2327738 DOI: 10.1002/Ana.410270313  0.302
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