Carmella Evans-Molina - Publications

Affiliations: 
Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Biochemistry, Molecular Biology, Endocrinology Biology

151 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sarkar S, Deiter C, Kyle JE, Guney MA, Sarbaugh D, Yin R, Li X, Cui Y, Ramos-Rodriguez M, Nicora CD, Syed F, Juan-Mateu J, Muralidharan C, Pasquali L, Evans-Molina C, et al. Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis. Cell Communication and Signaling : Ccs. 22: 141. PMID 38383396 DOI: 10.1186/s12964-023-01437-1  0.307
2023 McLaughlin MR, Weaver SA, Syed F, Evans-Molina C. Advanced Imaging Techniques for the Characterization of Subcellular Organelle Structure in Pancreatic Islet β Cells. Comprehensive Physiology. 14: 5243-5267. PMID 38158370 DOI: 10.1002/cphy.c230002  0.36
2023 Lee CC, Kono T, Syed F, Weaver SA, Sohn P, Wu W, Chang G, Liu J, Rupnik MS, Evans-Molina C. Histone Deacetylase Inhibitors Prevent Cytokine-Induced β Cell Dysfunction Through Restoration of Stromal Interaction Molecule 1 Expression and Activation of Store-Operated Calcium Entry. Biorxiv : the Preprint Server For Biology. PMID 38106138 DOI: 10.1101/2023.12.06.570443  0.347
2023 Sarkar S, Syed F, Webb-Robertson BJ, Melchior JT, Chang G, Gritsenko M, Wang YT, Tsai CF, Liu J, Yi X, Cui Y, Eizirik DL, Metz TO, Rewers M, Evans-Molina C, et al. Protection of β cells against pro-inflammatory cytokine stress by the GDF15-ERBB2 signaling. Medrxiv : the Preprint Server For Health Sciences. PMID 38076918 DOI: 10.1101/2023.11.27.23298904  0.622
2023 Curman P, Jebril W, Evans-Molina C, Bachar-Wikstrom E, Larsson H, Cederlöf M, Wikström JD. Hailey-Hailey Disease is Associated with Diabetes: A Population-based Cohort Study, Clinical Cohort Study, and Pedigree Analysis. Acta Dermato-Venereologica. 103: adv10436. PMID 38014829 DOI: 10.2340/actadv.v103.10436  0.329
2023 Sims EK, Kulkarni A, Hull A, Woerner SE, Cabrera S, Mastrandrea LD, Hammoud B, Sarkar S, Nakayasu ES, Mastracci TL, Perkins SM, Ouyang F, Webb-Robertson BJ, Enriquez JR, Tersey SA, ... Evans-Molina C, et al. Inhibition of polyamine biosynthesis preserves β cell function in type 1 diabetes. Cell Reports. Medicine. 101261. PMID 37918404 DOI: 10.1016/j.xcrm.2023.101261  0.786
2023 Felton JL, Griffin KJ, Oram RA, Speake C, Long SA, Onengut-Gumuscu S, Rich SS, Monaco GSF, Evans-Molina C, DiMeglio LA, Ismail HM, Steck AK, Dabelea D, Johnson RK, Urazbayeva M, et al. Disease-modifying therapies and features linked to treatment response in type 1 diabetes prevention: a systematic review. Communications Medicine. 3: 130. PMID 37794169 DOI: 10.1038/s43856-023-00357-y  0.344
2023 Vanderlaan EL, Sexton J, Evans-Molina C, Buganza Tepole A, Voytik-Harbin SL. Islet-on-chip: promotion of islet health and function encapsulation within a polymerizable fibrillar collagen scaffold. Lab On a Chip. 23: 4466-4482. PMID 37740372 DOI: 10.1039/d3lc00371j  0.324
2023 Ismail HM, Spall M, Evans-Molina C, DiMeglio LA. Evaluating the effect of prebiotics on the gut microbiome profile and β cell function in youth with newly diagnosed type 1 diabetes: protocol of a pilot randomized controlled trial. Pilot and Feasibility Studies. 9: 150. PMID 37626387 DOI: 10.1186/s40814-023-01373-4  0.411
2023 Iida H, Kono T, Lee CC, Krishnan P, Arvin MC, Weaver SA, Jarvela TS, Branco RCS, McLaughlin MR, Bone RN, Tong X, Arvan P, Lindberg I, Evans-Molina C. SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells. Diabetologia. PMID 37537395 DOI: 10.1007/s00125-023-05979-4  0.332
2023 Syed F, Krishnan P, Chang G, Langlais SR, Hati S, Yamada K, Lam AK, Talware S, Liu X, Sardar R, Liu J, Mirmira RG, Evans-Molina C. Title: β Cell microRNAs Function as Molecular Hubs of Type 1 Diabetes Pathogenesis and as Biomarkers of Diabetes Risk. Biorxiv : the Preprint Server For Biology. PMID 37398133 DOI: 10.1101/2023.06.15.545170  0.512
2023 Gitelman SE, Evans-Molina C, Guolo A, Mari A, Ferrannini E. ß-cell glucose sensitivity to assess changes in ß-cell function in recent onset stage 3 type 1 diabetes. Diabetes. PMID 37368990 DOI: 10.2337/db23-0196  0.361
2023 Perry DJ, Shapiro MR, Chamberlain SW, Kusmartseva I, Chamala S, Balzano-Nogueira L, Yang M, Brant JO, Brusko M, Williams MD, McGrail KM, McNichols J, Peters LD, Posgai AL, Kaddis JS, ... ... Evans-Molina C, et al. A genomic data archive from the Network for Pancreatic Organ donors with Diabetes. Scientific Data. 10: 323. PMID 37237059 DOI: 10.1038/s41597-023-02244-6  0.329
2023 Felton JL, Griffin KJ, Oram RA, Speake C, Long SA, Onengut-Gumuscu S, Rich SS, Monaco GS, Evans-Molina C, DiMeglio LA, Ismail HM, Steck AK, Dabelea D, Johnson RK, Urazbayeva M, et al. Type 1 Diabetes Prevention: a systematic review of studies testing disease-modifying therapies and features linked to treatment response. Medrxiv : the Preprint Server For Health Sciences. PMID 37131690 DOI: 10.1101/2023.04.12.23288421  0.35
2023 Davidson RK, Kanojia S, Wu W, Kono T, Xu J, Osmulski M, Bone RN, Casey N, Evans-Molina C, Sims EK, Spaeth JM. The Chd4 helicase regulates chromatin accessibility and gene expression critical for β-cell function in vivo. Diabetes. PMID 36913741 DOI: 10.2337/db22-0939  0.373
2023 Forlenza GP, McVean J, Beck RW, Bauza C, Bailey R, Buckingham B, DiMeglio LA, Sherr JL, Clements M, Neyman A, Evans-Molina C, Sims EK, Messer LH, Ekhlaspour L, McDonough R, et al. Effect of Verapamil on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes: A Randomized Clinical Trial. Jama. PMID 36826844 DOI: 10.1001/jama.2023.2064  0.313
2023 McVean J, Forlenza GP, Beck RW, Bauza C, Bailey R, Buckingham B, DiMeglio LA, Sherr JL, Clements M, Neyman A, Evans-Molina C, Sims EK, Messer LH, Ekhlaspour L, McDonough R, et al. Effect of Tight Glycemic Control on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes: A Randomized Clinical Trial. Jama. PMID 36826834 DOI: 10.1001/jama.2023.2063  0.382
2023 Evans-Molina C, Oram RA. Teplizumab approval for type 1 diabetes in the USA. The Lancet. Diabetes & Endocrinology. 11: 76-77. PMID 36623518 DOI: 10.1016/S2213-8587(22)00390-4  0.338
2022 Galderisi A, Evans-Molina C, Martino M, Caprio S, Cobelli C, Moran A. Beta cell function and insulin sensitivity in youth with early type 1 diabetes from a two-hour 7-sample OGTT. The Journal of Clinical Endocrinology and Metabolism. PMID 36546354 DOI: 10.1210/clinem/dgac740  0.348
2022 Syed F, Singhal D, Raedschelders K, Krishnan P, Bone RN, McLaughlin MR, Van Eyk JE, Mirmira RG, Yang ML, Mamula MJ, Wu H, Liu X, Evans-Molina C. A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes. Ebiomedicine. 87: 104379. PMID 36463755 DOI: 10.1016/j.ebiom.2022.104379  0.642
2022 Ferrannini E, Mari A, Monaco GSF, Skyler JS, Evans-Molina C. The effect of age on longitudinal measures of beta cell function and insulin sensitivity during the progression of early stage type 1 diabetes. Diabetologia. 1-12. PMID 36459177 DOI: 10.1007/s00125-022-05836-w  0.372
2022 Sims EK, Cuthbertson D, Felton JL, Ismail HM, Nathan BM, Jacobsen LM, Paprocki E, Pugliese A, Palmer J, Atkinson M, Evans-Molina C, Skyler JS, Redondo MJ, Herold KC, Sosenko JM. Persistence of β-Cell Responsiveness for Over Two Years in Autoantibody-Positive Children With Marked Metabolic Impairment at Screening. Diabetes Care. PMID 36326757 DOI: 10.2337/dc22-1362  0.317
2022 Dungan KM, Hart PA, Andersen DK, Basina M, Chinchilli VM, Danielson KK, Evans-Molina C, Goodarzi MO, Greenbaum CJ, Kalyani RR, Laughlin MR, Pichardo-Lowden A, Pratley RE, Serrano J, Sims EK, et al. Assessing the Pathophysiology of Hyperglycemia in the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study: From the Type 1 Diabetes in Acute Pancreatitis Consortium. Pancreas. 51: 575-579. PMID 36206461 DOI: 10.1097/MPA.0000000000002074  0.33
2022 Corkey BE, Kilpatrick LE, Evans-Molina C. Hypothesis: Induction of Autoimmunity in Type 1 Diabetes-A Lipid Focus. Diabetes. 71: 2067-2074. PMID 36126206 DOI: 10.2337/db22-0240  0.344
2022 Ismail HM, Cuthbertson D, Gitelman SE, Skyler JS, Steck AK, Rodriguez H, Atkinson M, Nathan BM, Redondo MJ, Herold KC, Evans-Molina C, DiMeglio LA, Sosenko J. The Transition From a Compensatory Increase to a Decrease in C-peptide During the Progression to Type 1 Diabetes and Its Relation to Risk. Diabetes Care. PMID 35998266 DOI: 10.2337/dc22-0167  0.315
2022 Carr ALJ, Evans-Molina C, Oram RA. Precision medicine in type 1 diabetes. Diabetologia. PMID 35994083 DOI: 10.1007/s00125-022-05778-3  0.382
2022 Cheheltani R, King N, Lee S, North B, Kovarik D, Evans-Molina C, Leavitt N, Dutta S. Predicting Misdiagnosed Adult-onset Type 1 Diabetes Using Machine Learning. Diabetes Research and Clinical Practice. 110029. PMID 35940302 DOI: 10.1016/j.diabres.2022.110029  0.3
2022 Piñeros AR, Kulkarni A, Gao H, Orr KS, Glenn L, Huang F, Liu Y, Gannon M, Syed F, Wu W, Anderson CM, Evans-Molina C, McDuffie M, Nadler JL, Morris MA, et al. Proinflammatory signaling in islet β cells propagates invasion of pathogenic immune cells in autoimmune diabetes. Cell Reports. 39: 111011. PMID 35767947 DOI: 10.1016/j.celrep.2022.111011  0.791
2022 Baidal DA, Warnock M, Xu P, Geyer S, Marks JB, Moran A, Sosenko J, Evans-Molina C. Oral Glucose Tolerance Test Measures of First-Phase Insulin Response and their Predictive Ability for Type 1 Diabetes. The Journal of Clinical Endocrinology and Metabolism. PMID 35524749 DOI: 10.1210/clinem/dgac285  0.388
2022 Davidson RK, Weaver SA, Casey N, Kanojia S, Hogarth E, Schneider Aguirre R, Sims EK, Evans-Molina C, Spaeth JM. The Chd4 subunit of the NuRD complex regulates Pdx1-controlled genes involved in β-cell function. Journal of Molecular Endocrinology. PMID 35521759 DOI: 10.1530/JME-22-0011  0.383
2021 Wu W, Syed F, Simpson E, Lee CC, Liu J, Chang G, Dong C, Seitz C, Eizirik DL, Mirmira RG, Liu Y, Evans-Molina C. The Impact of Pro-Inflammatory Cytokines on Alternative Splicing Patterns in Human Islets. Diabetes. PMID 34957512 DOI: 10.2337/db20-0847  0.586
2021 Cefalu WT, Andersen DK, Arreaza-Rubín G, Pin CL, Sato S, Verchere CB, Woo M, Rosenblum ND, Rosenblum N, Cefalu W, Andersen DK, Arreaza-Rubín G, Dhara C, James SP, ... ... Evans-Molina C, et al. Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases. Diabetes. PMID 34957490 DOI: 10.2337/db21-0777  0.33
2021 Reilly AM, Yan S, Huang M, Abhyankar SD, Conley JM, Bone RN, Stull ND, Horan DJ, Roh HC, Robling AG, Ericsson AC, Dong XC, Evans-Molina C, Ren H. A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues. The Journal of Biological Chemistry. 101431. PMID 34801552 DOI: 10.1016/j.jbc.2021.101431  0.338
2021 Wu W, Syed F, Simpson E, Lee CC, Liu J, Chang G, Dong C, Seitz C, Eizirik DL, Mirmira RG, Liu Y, Evans-Molina C. The Impact of Pro-Inflammatory Cytokines on Alternative Splicing Patterns in Human Islets. Diabetes. PMID 34697029 DOI: 10.2337/db20-0847  0.585
2021 Leslie RD, Evans-Molina C, Freund-Brown J, Buzzetti R, Dabelea D, Gillespie KM, Goland R, Jones AG, Kacher M, Phillips LS, Rolandsson O, Wardian JL, Dunne JL. Adult-Onset Type 1 Diabetes: Current Understanding and Challenges. Diabetes Care. 44: 2449-2456. PMID 34670785 DOI: 10.2337/dc21-0770  0.345
2021 Felton JL, Cuthbertson D, Warnock M, Lohano K, Meah F, Wentworth JM, Sosenko J, Evans-Molina C. HOMA2-B enhances assessment of type 1 diabetes risk among TrialNet Pathway to Prevention participants. Diabetologia. PMID 34642772 DOI: 10.1007/s00125-021-05573-6  0.376
2021 Anderson-Baucum E, Piñeros AR, Kulkarni A, Webb-Robertson BJ, Maier B, Anderson RM, Wu W, Tersey SA, Mastracci TL, Casimiro I, Scheuner D, Metz TO, Nakayasu ES, Evans-Molina C, Mirmira RG. Deoxyhypusine synthase promotes a pro-inflammatory macrophage phenotype. Cell Metabolism. 33: 1883-1893.e7. PMID 34496231 DOI: 10.1016/j.cmet.2021.08.003  0.702
2021 Voss MG, Cuthbertson DD, Cleves MM, Xu P, Evans-Molina C, Palmer JP, Redondo MJ, Steck AK, Lundgren M, Larsson H, Moore WV, Atkinson MA, Sosenko JM, Ismail HM. Time to Peak Glucose and Peak C-Peptide During the Progression to Type 1 Diabetes in the Diabetes Prevention Trial and TrialNet Cohorts. Diabetes Care. PMID 34362815 DOI: 10.2337/dc21-0226  0.359
2021 Redondo MJ, Warnock MV, Libman IM, Bocchino LE, Cuthbertson D, Geyer S, Pugliese A, Steck AK, Evans-Molina C, Becker D, Sosenko JM, Bacha F. Genetic Variants Do Not Influence Insulin Sensitivity or Secretion Indices in Autoantibody-Positive Individuals at Risk for Type 1 Diabetes. Diabetes Care. 44: 2039-2044. PMID 34326068 DOI: 10.2337/dc21-0531  0.371
2021 Sims EK, Carr ALJ, Oram RA, DiMeglio LA, Evans-Molina C. 100 years of insulin: celebrating the past, present and future of diabetes therapy. Nature Medicine. 27: 1154-1164. PMID 34267380 DOI: 10.1038/s41591-021-01418-2  0.331
2021 Galderisi A, Moran A, Evans-Molina C, Martino M, Santoro N, Caprio S, Cobelli C. Early impairment of insulin sensitivity, β-cell responsiveness, and insulin clearance in youth with Stage 1 type 1 diabetes. The Journal of Clinical Endocrinology and Metabolism. PMID 34000022 DOI: 10.1210/clinem/dgab344  0.382
2021 Rodriguez-Calvo T, Chen YC, Verchere CB, Haataja L, Arvan P, Leete P, Richardson SJ, Morgan NG, Qian WJ, Pugliese A, Atkinson M, Evans-Molina C, Sims EK. Altered β-Cell Prohormone Processing and Secretion in Type 1 Diabetes. Diabetes. PMID 33947721 DOI: 10.2337/dbi20-0034  0.366
2021 Triolo TM, Pyle L, Seligova S, Yu L, Simmons K, Gottlieb P, Evans-Molina C, Steck AK. Proinsulin:C-peptide ratio trajectories over time in relatives at increased risk of progression to type 1 diabetes. Journal of Translational Autoimmunity. 4: 100089. PMID 33748733 DOI: 10.1016/j.jtauto.2021.100089  0.328
2021 Sims EK, Bundy BN, Stier K, Serti E, Lim N, Long SA, Geyer SM, Moran A, Greenbaum CJ, Evans-Molina C, Herold KC. Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals. Science Translational Medicine. 13. PMID 33658358 DOI: 10.1126/scitranslmed.abc8980  0.308
2020 Bone RN, Oyebamiji O, Talware S, Selvaraj S, Krishnan P, Syed F, Wu H, Evans-Molina C. A Computational Approach for Defining a Signature of β-Cell Golgi Stress in Diabetes Mellitus. Diabetes. PMID 32820009 DOI: 10.2337/Db20-0636  0.434
2020 Syed F, Tersey SA, Turatsinze JV, Felton JL, Kang NJ, Nelson JB, Sims EK, Defrance M, Bizet M, Fuks F, Cnop M, Bugliani M, Marchetti P, Ziegler AG, Bonifacio E, ... ... Evans-Molina C, et al. Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes. Clinical Epigenetics. 12: 116. PMID 32736653 DOI: 10.1186/S13148-020-00906-5  0.687
2020 Sims EK, Mirmira RG, Evans-Molina C. The role of beta-cell dysfunction in early type 1 diabetes. Current Opinion in Endocrinology, Diabetes, and Obesity. 27: 215-224. PMID 32618633 DOI: 10.1097/Med.0000000000000548  0.685
2020 Coomans de Brachène A, Castela A, Op de Beeck A, Mirmira RG, Marselli L, Marchetti P, Masse C, Miao W, Leit S, Evans-Molina C, Eizirik DL. Pre-clinical evaluation of TYK2 inhibitors for human beta cell protection in type 1 diabetes. Diabetes, Obesity & Metabolism. PMID 32476252 DOI: 10.1111/dom.14104  0.61
2020 Tong X, Chaudry Z, Lee CC, Bone RN, Kanojia S, Maddatu J, Sohn P, Weaver SA, Robertson MA, Petrache I, Evans-Molina C, Kono T. Cigarette smoke exposure impairs β-cell function through activation of oxidative stress and ceramide accumulation. Molecular Metabolism. 100975. PMID 32283079 DOI: 10.1016/J.Molmet.2020.100975  0.358
2020 Ferrara-Cook C, Geyer SM, Evans-Molina C, Libman IM, Becker DJ, Gitelman SE, Redondo MJ. Excess BMI Accelerates Islet Autoimmunity in Older Children and Adolescents. Diabetes Care. PMID 31937610 DOI: 10.2337/Dc19-1167  0.425
2020 Nakayasu ES, Syed F, Tersey SA, Gritsenko MA, Mitchell HD, Chan CY, Dirice E, Turatsinze JV, Cui Y, Kulkarni RN, Eizirik DL, Qian WJ, Webb-Robertson BM, Evans-Molina C, Mirmira RG, et al. Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention. Cell Metabolism. PMID 31928885 DOI: 10.1016/J.Cmet.2019.12.005  0.681
2020 Speake C, Ylescupidez A, Neiman D, Shemer R, Glaser B, Tersey SA, Usmani-Brown S, Clark P, Wilhelm JJ, Bellin MD, Herold KC, Mirmira RG, Dor Y, Evans-Molina C. Circulating unmethylated insulin DNA as a biomarker of human beta cell death: a multi-laboratory assay comparison. The Journal of Clinical Endocrinology and Metabolism. PMID 31913467 DOI: 10.1210/Clinem/Dgaa008  0.63
2020 Rickels MR, Evans-Molina C, Bahnson HT, Ylescupidez A, Nadeau KJ, Hao W, Clements MA, Sherr JL, Pratley RE, Hannon TS, Shah VN, Miller KM, Greenbaum CJ. High residual C-peptide likely contributes to glycemic control in type 1 diabetes. The Journal of Clinical Investigation. PMID 31895699 DOI: 10.1172/Jci134057  0.37
2020 Ismail HM, Skyler JS, Sosenko J, Palmer JP, Evans-Molina C, Dimeglio L, Redondo MJ, Steck A, Atkinson MA, Herold KC, Nathan BM. 99-OR: An Inflection Point (IP) of C-Peptide (C-P) Decline during Progression to Type 1 Diabetes (T1D) Diabetes. 69. DOI: 10.2337/Db20-99-Or  0.304
2020 Syed F, Maier BF, Anderson-Baucum E, Mastracci TL, Evans-Molina C, Mirmira R. 82-OR: Exosomes from Human ß-Cells Incorporate Stress Granule Components and May Serve as Biomarkers of ß-Cell Stress in Type 1 Diabetes Diabetes. 69. DOI: 10.2337/Db20-82-Or  0.636
2020 Wu W, Syed F, Simpson E, Lee C, Eizirik DL, Mirmira R, Liu Y, Evans-Molina C. 81-OR: The Impact of Proinflammatory Cytokines on Human Pancreatic Islet Alternative Splicing Patterns Diabetes. 69. DOI: 10.2337/Db20-81-Or  0.557
2020 Kono T, Iida H, Jarvela TS, Lee C, Tong X, Arvan P, Lindberg I, Evans-Molina C. 48-OR: Pancreatic ß Cell SERCA2 Deficiency Leads to Impaired Proinsulin Processing and Reduced ER to Golgi Protein Trafficking Diabetes. 69. DOI: 10.2337/Db20-48-Or  0.456
2020 Evans-Molina C, Saeed ZI, Sosenko J, Atkinson MA, Herold KC, Ismail HM, Larsson HE, Lundgren M, Moran A, Moore DJ, Nathan BM, Palmer JP, Sims EK, Steck A, Wherrett DK, et al. 348-OR: Metabolic Phenotype of Autoantibody Positive (AbPos) Long-Term Nonprogressors (LTNPs) to Type 1 Diabetes (T1D) Diabetes. 69. DOI: 10.2337/Db20-348-Or  0.338
2020 Felton JL, Lohano K, Meah F, Sosenko J, Evans-Molina C. 343-OR: HOMA2ß Stratifies Risk for Type 1 Diabetes (T1D) Development among TrialNet Pathway to Prevention Participants Diabetes. 69. DOI: 10.2337/Db20-343-Or  0.415
2020 SIMS EK, BUNDY BN, STIER KD, SERTI E, LIM N, NEPOM GT, EVANS-MOLINA C, HEROLD KC. 277-OR: Teplizumab Reverses the Loss of C-Peptide in Relatives at Risk for Type 1 Diabetes (T1D) Diabetes. 69: 277-OR. DOI: 10.2337/Db20-277-Or  0.395
2020 Bone RN, Reissaus CA, Kono T, Evans-Molina C. 2112-P: Sarco/Endoplasmic Reticulum ATPase (SERCA2) Deficiency in the Nonobese Diabetic (NOD) Mouse Accelerates Type 1 Diabetes Development Diabetes. 69. DOI: 10.2337/Db20-2112-P  0.452
2020 Lee C, Kono T, Weaver SA, Sohn P, Evans-Molina C. 2074-P: Histone Deacetylase Inhibitors Improve Store-Operated Calcium Entry and Glucose-Stimulated Insulin Secretion in Cytokine-Stressed Pancreatic ß-Cells Diabetes. 69. DOI: 10.2337/Db20-2074-P  0.374
2020 Syed F, Krishnan P, Restrepo I, Mirmira R, Evans-Molina C. 2034-P: ß Cell miRNAs Function as Molecular Hubs of Type 1 Diabetes Pathogenesis and Risk Diabetes. 69. DOI: 10.2337/Db20-2034-P  0.627
2020 Neyman A, Moors K, Evans-Molina C, Dimeglio L, Mirmira R, Mather KJ, Hannon TS, Sims EK. 1616-P: Stimulated ß-Cell Response Is Unaltered in Adult Autoantibody (AB) Negative Relatives of Individuals with Type 1 Diabetes (T1D) Diabetes. 69. DOI: 10.2337/Db20-1616-P  0.63
2020 Virostko J, Williams JM, Hilmes MA, Du L, Kang H, Russell WE, Triolo TM, Philipson LH, Sims EK, Evans-Molina C, Thomas HE, Kay T, Greeley SAW, Steck A, Powers AC, et al. 1283-P: Multicenter Assessment of the Pancreas in Type 1 Diabetes (MAP-T1D) Diabetes. 69. DOI: 10.2337/Db20-1283-P  0.397
2020 Redondo MJ, Warnock MV, Bocchino LE, Geyer S, Pugliese A, Steck A, Libman I, Evans-Molina C, Becker DJ, Sosenko J, Bacha F. 110-OR: Type 2 Diabetes (T2D)–Associated TCF7L2 Genetic Variants and Indices of Insulin Secretion and Sensitivity in Individuals at Risk for Type 1 Diabetes (T1D) Diabetes. 69. DOI: 10.2337/Db20-110-Or  0.435
2020 Jiang H, Griesenauer B, Tersey SA, Orr K, Evans-Molina C, Paczesny S. Preventing Post-Transplant Diabetes Mellitus Via Orchestration of the IL-33/ST2 Axis in Pancreatic Islets Biology of Blood and Marrow Transplantation. 26. DOI: 10.1016/J.Bbmt.2019.12.029  0.458
2019 Krishnan P, Syed F, Jiyun Kang N, G Mirmira R, Evans-Molina C. Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes. International Journal of Molecular Sciences. 20. PMID 31775218 DOI: 10.3390/Ijms20235903  0.358
2019 Jacobsen LM, Bocchino L, Evans-Molina C, DiMeglio L, Goland R, Wilson DM, Atkinson MA, Aye T, Russell WE, Wentworth JM, Boulware D, Geyer S, Sosenko JM. The risk of progression to type 1 diabetes is highly variable in individuals with multiple autoantibodies following screening. Diabetologia. PMID 31768570 DOI: 10.1007/S00125-019-05047-W  0.351
2019 Battaglia M, Ahmed S, Anderson MS, Atkinson MA, Becker D, Bingley PJ, Bosi E, Brusko TM, DiMeglio LA, Evans-Molina C, Gitelman SE, Greenbaum CJ, Gottlieb PA, Herold KC, Hessner MJ, et al. Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes. Diabetes Care. PMID 31753960 DOI: 10.2337/Dc19-0880  0.423
2019 Beli E, Prabakaran S, Krishnan P, Evans-Molina C, Grant MB. Loss of Diurnal Oscillatory Rhythms in Gut Microbiota Correlates with Changes in Circulating Metabolites in Type 2 Diabetic db/db Mice. Nutrients. 11. PMID 31569518 DOI: 10.3390/Nu11102310  0.396
2019 Sims EK, Syed F, Nyalwidhe J, Bahnson HT, Haataja L, Speake C, Morris MA, Balamurugan AN, Mirmira RG, Nadler J, Mastracci TL, Arvan P, Greenbaum CJ, Evans-Molina C. Abnormalities in proinsulin processing in islets from individuals with longstanding T1D. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 31442418 DOI: 10.1016/J.Trsl.2019.08.001  0.642
2019 Xu G, Thielen LA, Chen J, Grayson TB, Grimes T, Bridges SL, Tse HM, Smith B, Patel R, Li P, Evans-Molina C, Ovalle F, Shalev A. Serum miR-204 is an early biomarker of type 1 diabetes-associated pancreatic beta-cell loss. American Journal of Physiology. Endocrinology and Metabolism. PMID 31408375 DOI: 10.1152/Ajpendo.00122.2019  0.407
2019 Nakayasu ES, Qian WJ, Evans-Molina C, Mirmira RG, Eizirik DL, Metz TO. The role of proteomics in assessing beta-cell dysfunction and death in type 1 diabetes. Expert Review of Proteomics. 1-14. PMID 31232620 DOI: 10.1080/14789450.2019.1634548  0.636
2019 Redondo MJ, Evans-Molina C, Steck AK, Atkinson MA, Sosenko J. The Influence of Type 2 Diabetes-Associated Factors on Type 1 Diabetes. Diabetes Care. PMID 31167894 DOI: 10.2337/Dc19-0102  0.518
2019 Brissova M, Niland JC, Cravens J, Olack B, Sowinski J, Evans-Molina C. The Integrated Islet Distribution Program Answers the Call for Improved Human Islet Phenotyping and Reporting of Human Islet Characteristics in Research Articles. Diabetes. 68: 1363-1365. PMID 31092479 DOI: 10.2337/Dbi19-0019  0.388
2019 Sims EK, Bahnson HT, Nyalwidhe J, Haataja L, Davis AK, Speake C, DiMeglio LA, Blum J, Morris MA, Mirmira RG, Nadler J, Mastracci TL, Marcovina S, Qian WJ, Yi L, ... ... Evans-Molina C, et al. Response to Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264. Diabetes Care. 42: e85-e86. PMID 31010952 DOI: 10.2337/Dci19-0012  0.619
2019 Ismail HM, Evans-Molina C, DiMeglio LA, Becker DJ, Libman I, Sims EK, Boulware D, Herold KC, Rafkin L, Skyler J, Cleves MA, Palmer J, Sosenko J. Associations of HbA1c with the Timing of C-peptide Responses during the Oral Glucose Tolerance Test at the Diagnosis of Type 1 Diabetes. Pediatric Diabetes. PMID 30891858 DOI: 10.1111/Pedi.12845  0.374
2019 Oram RA, Sims EK, Evans-Molina C. Beta cells in type 1 diabetes: mass and function; sleeping or dead? Diabetologia. PMID 30767048 DOI: 10.1007/S00125-019-4822-4  0.432
2019 Ocaña GJ, Sims EK, Watkins RA, Ragg S, Mather KJ, Oram RA, Mirmira RG, DiMeglio LA, Blum JS, Evans-Molina C. Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes. Plos One. 14: e0208456. PMID 30629603 DOI: 10.1371/Journal.Pone.0208456  0.65
2019 Iida H, Kono T, Tong X, Lindberg I, Evans-Molina C. 341-LB: Chronic ER Calcium Depletion Resulting from Sarcoendoplasmic Reticulum Ca2+ Atpase 2b (SERCA2b) Deficiency Leads to Impaired Proinsulin Processing in the Pancreatic ß Cell Diabetes. 68. DOI: 10.2337/Db19-341-Lb  0.45
2019 ANNA N, EVANS-MOLINA C, DIMEGLIO L, MIRMIRA R, MATHER KJ, HANNON TS, SIMS EK. 230-LB: Intraindividual Variability of Measures of Beta-Cell Response Diabetes. 68: 230-LB. DOI: 10.2337/Db19-230-Lb  0.603
2019 Beli E, Dimeglio L, Woerner S, Evans-Molina C, Mcgrail KM, Wasserfall C, Atkinson MA, Beam C. 1729-P: Circadian Patterns of Autoimmune Components in the Blood of Persons with Type 1 Diabetes: Implications for the Timing of Blood Sampling Diabetes. 68. DOI: 10.2337/Db19-1729-P  0.337
2019 Triolo TM, Pyle L, Seligova S, Yu L, Simmons K, Gottlieb P, Evans-Molina C, Steck A. 1669-P: Proinsulin: C-Peptide Ratios in Relatives of Persons with Type 1 Diabetes Diabetes. 68. DOI: 10.2337/Db19-1669-P  0.364
2018 Sims EK, Bahnson HT, Nyalwidhe J, Haataja L, Davis AK, Speake C, DiMeglio LA, Blum J, Morris MA, Mirmira RG, Nadler J, Mastracci TL, Marcovina S, Qian WJ, Yi L, ... ... Evans-Molina C, et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care. PMID 30530850 DOI: 10.2337/Dc17-2625  0.639
2018 Yamamoto WR, Bone RN, Sohn P, Syed F, Reissaus CA, Mosley AL, Wijeratne AB, True JD, Tong X, Kono T, Evans-Molina C. Endoplasmic reticulum stress alters ryanodine receptor function in the murine pancreatic β cell. The Journal of Biological Chemistry. PMID 30420428 DOI: 10.1074/Jbc.Ra118.005683  0.428
2018 Leete P, Mallone R, Richardson SJ, Sosenko JM, Redondo MJ, Evans-Molina C. The Effect of Age on the Progression and Severity of Type 1 Diabetes: Potential Effects on Disease Mechanisms. Current Diabetes Reports. 18: 115. PMID 30259209 DOI: 10.1007/S11892-018-1083-4  0.424
2018 Wentworth JM, Bediaga NG, Giles LC, Ehlers M, Gitelman SE, Geyer S, Evans-Molina C, Harrison LC. Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables. Diabetologia. PMID 30167735 DOI: 10.1007/S00125-018-4722-Z  0.421
2018 Kono T, Tong X, Taleb S, Bone RN, Iida H, Lee CC, Sohn P, Gilon P, Roe MW, Evans-Molina C. Impaired Store-Operated Calcium Entry and STIM1 Loss Lead to Reduced Insulin Secretion and Increased Endoplasmic Reticulum Stress in the Diabetic β cell. Diabetes. PMID 30131394 DOI: 10.2337/Db17-1351  0.481
2018 Sims EK, Evans-Molina C, Tersey SA, Eizirik DL, Mirmira RG. Biomarkers of islet beta cell stress and death in type 1 diabetes. Diabetologia. PMID 30112687 DOI: 10.1007/S00125-018-4712-1  0.655
2018 Evans-Molina C, Sims EK, DiMeglio LA, Ismail HM, Steck AK, Palmer JP, Krischer JP, Geyer S, Xu P, Sosenko JM. β Cell dysfunction exists more than 5 years before type 1 diabetes diagnosis. Jci Insight. 3. PMID 30089716 DOI: 10.1172/Jci.Insight.120877  0.507
2018 Neyman A, Nelson J, Tersey S, Mirmira RG, Evans-Molina C, Sims EK. Persistent Elevations in Circulating INS DNA Among Subjects with Longstanding Type 1 Diabetes. Diabetes, Obesity & Metabolism. PMID 30073765 DOI: 10.1111/dom.13489  0.61
2018 Beli E, Yan Y, Moldovan L, Vieira CP, Gao R, Duan Y, Prasad R, Bhatwadekar A, White FA, Townsend S, Chan L, Ryan CN, Morton D, Moldovan EG, Chu FI, ... ... Evans-Molina C, et al. Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice. Diabetes. PMID 29712667 DOI: 10.2337/Db18-0158  0.618
2018 Syed F, Evans-Molina C. Nucleic acid biomarkers of β cell stress and death in type 1 diabetes. Current Opinion in Endocrinology, Diabetes, and Obesity. 23: 312-7. PMID 27254268 DOI: 10.1097/MED.0000000000000261  0.359
2018 Bosi E, Geyer S, Sosenko J, Becker DJ, Battaglia M, Ismail HM, Atkinson MA, Philipson LH, Palmer JP, Evans-Molina C. Metabolic Markers Associated with Increased Risk for Progression from Single to Multiple Autoantibodies in Type 1 Diabetes Relatives Diabetes. 67. DOI: 10.2337/Db18-94-Or  0.4
2018 Bone RN, Kono T, Evans-Molina C. Reduced ß Cell SPCA1 Leads to Impaired Calcium Oscillations and Decreased Autophagy Diabetes. 67. DOI: 10.2337/Db18-194-Or  0.424
2018 Ismail HM, Xu P, Evans-Molina C, Palmer JP, Sosenko J. Time-to-Peak C-Peptide and Peak Glucose during an Oral Glucose Tolerance Test (OGTT) Are Independent Risk Factors for Type 1 Diabetes (T1D) in Antibody-Positive (Ab+) Individuals Diabetes. 67. DOI: 10.2337/Db18-1688-P  0.338
2017 Sosenko JM, Geyer S, Skyler JS, Rafkin LE, Ismail HM, Libman IM, Liu YF, DiMeglio LA, Evans-Molina C, Palmer JP. The influence of body mass index and age on C-peptide at the diagnosis of type 1 diabetes in children who participated in the diabetes prevention trial-type 1. Pediatric Diabetes. PMID 29171129 DOI: 10.1111/Pedi.12609  0.379
2017 Ferrara CT, Geyer S, Evans-Molina C, Libman I, Becker D, Wentworth JM, Moran A, Gitelman S, Redondo MJ. The Role of Age and Excess Body Mass Index in Progression to Type 1 Diabetes in At-Risk Adults. The Journal of Clinical Endocrinology and Metabolism. PMID 29092051 DOI: 10.1210/Jc.2017-01490  0.415
2017 Nathan BM, Boulware D, Geyer S, Atkinson MA, Colman P, Goland R, Russell W, Wentworth JM, Wilson DM, Evans-Molina C, Wherrett D, Skyler JS, Moran A, Sosenko JM. Dysglycemia and Index60 as Prediagnostic End Points for Type 1 Diabetes Prevention Trials. Diabetes Care. PMID 28860125 DOI: 10.2337/Dc17-0916  0.453
2017 Hatanaka M, Anderson-Baucum E, Lakhter A, Kono T, Maier B, Tersey SA, Tanizawa Y, Evans-Molina C, Mirmira RG, Sims EK. Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation. Scientific Reports. 7: 3758. PMID 28630491 DOI: 10.1038/S41598-017-03869-5  0.633
2017 Bone RN, Evans-Molina C. Combination Immunotherapy for Type 1 Diabetes. Current Diabetes Reports. 17: 50. PMID 28534310 DOI: 10.1007/S11892-017-0878-Z  0.465
2017 Gordon HM, Majithia N, MacDonald PE, Fox JE, Sharma PR, Byrne FL, Hoehn KL, Evans-Molina C, Langman L, Brayman KL, Nunemaker CS. STEAP4 expression in human islets is associated with differences in body mass index, sex, HbA1c, and inflammation. Endocrine. PMID 28405880 DOI: 10.1007/S12020-017-1297-2  0.421
2017 Maddatu J, Anderson-Baucum E, Evans-Molina C. Smoking and the risk of type 2 diabetes. Translational Research. 184: 101-107. PMID 28336465 DOI: 10.1016/J.Trsl.2017.02.004  0.389
2017 Sims EK, Lakhter AJ, Anderson-Baucum E, Kono T, Tong X, Evans-Molina C. MicroRNA 21 targets BCL2 mRNA to increase apoptosis in rat and human beta cells. Diabetologia. PMID 28280903 DOI: 10.1007/S00125-017-4237-Z  0.363
2017 Ferrara CT, Geyer SM, Liu YF, Evans-Molina C, Libman IM, Besser R, Becker DJ, Rodriguez H, Moran A, Gitelman SE, Redondo MJ. Excess BMI in Childhood: A Modifiable Risk Factor for Type 1 Diabetes Development. Diabetes Care. PMID 28202550 DOI: 10.2337/Dc16-2331  0.43
2017 Ocaña GJ, Pérez L, Guindon L, Deffit SN, Evans-Molina C, Thurmond DC, Blum JS. Inflammatory stress of pancreatic beta cells drives release of extracellular heat shock protein 90α. Immunology. PMID 28190264 DOI: 10.1111/Imm.12723  0.411
2016 Saeed Z, Taleb S, Evans-Molina C. A case of extragastrointestinal stromal tumor complicated by severe hypoglycemia: a unique presentation of a rare tumor Bmc Cancer. 16: 930-930. PMID 27905899 DOI: 10.1186/S12885-016-2968-8  0.309
2016 Mirmira RG, Sims EK, Syed F, Evans-Molina C. Biomarkers of β-Cell Stress and Death in Type 1 Diabetes. Current Diabetes Reports. 16: 95. PMID 27541297 DOI: 10.1007/S11892-016-0783-X  0.668
2016 Tong X, Kono T, Anderson-Baucum EK, Yamamoto W, Gilon PM, Lebeche D, Day RN, Schull GE, Evans-Molina C. SERCA2 Deficiency Impairs Pancreatic β Cell Function in Response to Diet-Induced Obesity. Diabetes. PMID 27489309 DOI: 10.2337/Db16-0084  0.443
2016 Sims EK, Chaudhry Z, Watkins R, Syed F, Blum J, Ouyang F, Perkins SM, Mirmira RG, Sosenko J, DiMeglio LA, Evans-Molina C. Elevations in the Fasting Serum Proinsulin-to-C-Peptide Ratio Precede the Onset of Type 1 Diabetes. Diabetes Care. PMID 27385327 DOI: 10.2337/Dc15-2849  0.637
2016 Meah FA, DiMeglio LA, Greenbaum CJ, Blum JS, Sosenko JM, Pugliese A, Geyer S, Xu P, Evans-Molina C. The relationship between BMI and insulin resistance and progression from single to multiple autoantibody positivity and type 1 diabetes among TrialNet Pathway to Prevention participants. Diabetologia. PMID 26995649 DOI: 10.1007/S00125-016-3924-5  0.481
2016 Morris DL, Evans-Molina C. Metabolic dysfunction and adipose tissue macrophages: is there more to glean from studying the lean?: Comment on "Adipose tissue infiltration in normal-weight subjects and its impact on metabolic function" by Moreno-Indias et al. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 26963742 DOI: 10.1016/J.Trsl.2016.02.010  0.377
2016 Pugliese A, Boulware D, Yu L, Babu S, Steck AK, Becker D, Rodriguez H, DiMeglio L, Evans-Molina C, Harrison LC, Schatz D, Palmer JP, Greenbaum C, Eisenbarth GS, Sosenko JM, et al. The HLA-DRB1*15:01-DQA1*01:02-DQB1*06:02 haplotype protects autoantibody-positive relatives from type 1 diabetes throughout the stages of disease progression. Diabetes. PMID 26822082 DOI: 10.2337/Db15-1105  0.399
2016 Sims E, Lakhter A, Restrepo I, Tong X, Kono T, Anderson-Baucum E, Evans-Molina C. ID: 84: β CELL DERIVED MIR-21 INCREASES APOPTOSIS VIA TRANSLATIONAL INHIBITION OF THE ANTIAPOPTOTIC PROTEIN BCL2 AND COULD SERVE AS A BIOMARKER OF TYPE 1 DIABETES MELLITUS Journal of Investigative Medicine. 64: 927-928. DOI: 10.1136/Jim-2016-000120.35  0.347
2016 Syed F, Evans-Molina C. Nucleic acid biomarkers of β cell stress and death in type 1 diabetes Current Opinion in Endocrinology, Diabetes and Obesity. 23: 312-317. DOI: 10.1097/Med.0000000000000261  0.487
2015 Xiong X, Wang G, Tao R, Wu P, Kono T, Li K, Ding WX, Tong X, Tersey SA, Harris RA, Mirmira RG, Evans-Molina C, Dong XC. Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells. Diabetologia. PMID 26471901 DOI: 10.1007/S00125-015-3778-2  0.606
2015 Watkins RA, Evans-Molina C, Terrell JK, Day KH, Guindon L, Restrepo IA, Mirmira RG, Blum JS, DiMeglio LA. Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 26397425 DOI: 10.1016/J.Trsl.2015.08.010  0.655
2015 Fisher MM, Watkins RA, Blum J, Evans-Molina C, Chalasani N, DiMeglio LA, Mather KJ, Tersey SA, Mirmira RG. Elevations in Circulating Methylated and Unmethylated Preproinsulin DNA in New-Onset Type 1 Diabetes. Diabetes. 64: 3867-72. PMID 26216854 DOI: 10.2337/Db15-0430  0.576
2015 Tong X, Kono T, Evans-Molina C. Nitric oxide stress and activation of AMP-activated protein kinase impair β-cell sarcoendoplasmic reticulum calcium ATPase 2b activity and protein stability. Cell Death & Disease. 6: e1790. PMID 26086963 DOI: 10.1038/Cddis.2015.154  0.414
2015 Fujimaki K, Ogihara T, Morris DL, Oda H, Iida H, Fujitani Y, Mirmira RG, Evans-Molina C, Watada H. Set7/9 Regulates Cytokine-Induced Expression of Inducible Nitric Oxide Synthase Through Methylation of Lysine 4 at Histone 3 in the Islet β cell. The Journal of Biological Chemistry. PMID 25995453 DOI: 10.1074/Jbc.M115.661777  0.626
2015 Filgueiras LR, Brandt SL, Wang S, Wang Z, Morris DL, Evans-Molina C, Mirmira RG, Jancar S, Serezani CH. Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes. Science Signaling. 8: ra10. PMID 25628460 DOI: 10.1126/Scisignal.2005568  0.648
2015 Blue EK, Ballman K, Boyle F, Oh E, Kono T, Quinney SK, Thurmond DC, Evans-Molina C, Haneline LS. Fetal hyperglycemia and a high-fat diet contribute to aberrant glucose tolerance and hematopoiesis in adult rats. Pediatric Research. 77: 316-25. PMID 25412163 DOI: 10.1038/Pr.2014.185  0.389
2015 Johnson JS, Evans-Molina C. Translational implications of the β-cell epigenome in diabetes mellitus. Translational Research : the Journal of Laboratory and Clinical Medicine. 165: 91-101. PMID 24686035 DOI: 10.1016/J.Trsl.2014.03.002  0.536
2014 Maganti A, Evans-Molina C, Mirmira R. From immunobiology to β-cell biology: the changing perspective on type 1 diabetes. Islets. 6: e28778. PMID 25483958 DOI: 10.4161/Isl.28778  0.675
2014 Johnson JS, Kono T, Tong X, Yamamoto WR, Zarain-Herzberg A, Merrins MJ, Satin LS, Gilon P, Evans-Molina C. Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell. The Journal of Biological Chemistry. 289: 32798-810. PMID 25271154 DOI: 10.1074/Jbc.M114.575191  0.439
2014 Hatanaka M, Maier B, Sims EK, Templin AT, Kulkarni RN, Evans-Molina C, Mirmira RG. Palmitate induces mRNA translation and increases ER protein load in islet β-cells via activation of the mammalian target of rapamycin pathway. Diabetes. 63: 3404-15. PMID 24834975 DOI: 10.2337/Db14-0105  0.781
2014 Mirmira P, Evans-Molina C. Bisphenol A, obesity, and type 2 diabetes mellitus: Genuine concern or unnecessary preoccupation? Translational Research. 164: 13-21. PMID 24686036 DOI: 10.1016/J.Trsl.2014.03.003  0.356
2014 Watkins RA, Evans-Molina C, Blum JS, DiMeglio LA. Established and emerging biomarkers for the prediction of type 1 diabetes: a systematic review. Translational Research : the Journal of Laboratory and Clinical Medicine. 164: 110-21. PMID 24662515 DOI: 10.1016/J.Trsl.2014.02.004  0.443
2014 Handa RK, Evan AP, Connors BA, Johnson CD, Liu Z, Alloosh M, Sturek M, Evans-Molina C, Mandeville JA, Gnessin E, Lingeman JE. Shock wave lithotripsy targeting of the kidney and pancreas does not increase the severity of metabolic syndrome in a porcine model. The Journal of Urology. 192: 1257-65. PMID 24657667 DOI: 10.1016/J.Juro.2014.03.035  0.317
2014 Kono TM, Sims EK, Moss DR, Yamamoto W, Ahn G, Diamond J, Tong X, Day KH, Territo PR, Hanenberg H, Traktuev DO, March KL, Evans-Molina C. Human adipose-derived stromal/stem cells protect against STZ-induced hyperglycemia: analysis of hASC-derived paracrine effectors. Stem Cells (Dayton, Ohio). 32: 1831-42. PMID 24519994 DOI: 10.1002/Stem.1676  0.491
2014 Rajashekhar G, Ramadan A, Abburi C, Callaghan B, Traktuev DO, Evans-Molina C, Maturi R, Harris A, Kern TS, March KL. Regenerative therapeutic potential of adipose stromal cells in early stage diabetic retinopathy. Plos One. 9: e84671. PMID 24416262 DOI: 10.1371/Journal.Pone.0084671  0.402
2014 Sims EK, Evans-Molina C. Urinary biomarkers for the early diagnosis of retinopathy and nephropathy in type 1 diabetes mellitus: a "steady stream" of information using proteomics. Translational Research : the Journal of Laboratory and Clinical Medicine. 163: 183-7. PMID 24355258 DOI: 10.1016/J.Trsl.2013.11.013  0.474
2013 DiMeglio LA, Evans-Molina C, Oram RA. Type 1-diabetes The Lancet. 391: 2449-2462. PMID 29916386 DOI: 10.1016/S0140-6736(18)31320-5  0.471
2013 Sims EK, Hatanaka M, Morris DL, Tersey SA, Kono T, Chaudry ZZ, Day KH, Moss DR, Stull ND, Mirmira RG, Evans-Molina C. Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strains. American Journal of Physiology. Endocrinology and Metabolism. 305: E1495-511. PMID 24169046 DOI: 10.1152/Ajpendo.00366.2013  0.604
2013 Evans-Molina C, Hatanaka M, Mirmira RG. Lost in translation: endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus. Diabetes, Obesity & Metabolism. 15: 159-69. PMID 24003933 DOI: 10.1111/Dom.12163  0.668
2013 So WY, Cheng Q, Chen L, Evans-Molina C, Xu A, Lam KS, Leung PS. High glucose represses β-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: involvement of peroxisome proliferator-activated receptor γ signaling. Diabetes. 62: 3751-9. PMID 23897951 DOI: 10.2337/Db13-0645  0.465
2013 Chaudhry ZZ, Morris DL, Moss DR, Sims EK, Chiong Y, Kono T, Evans-Molina C. Streptozotocin is equally diabetogenic whether administered to fed or fasted mice. Laboratory Animals. 47: 257-65. PMID 23760565 DOI: 10.1177/0023677213489548  0.392
2013 Evans-Molina C, Mirmira RG. Achieving "PeaK-A" insulin secretion. Diabetes. 62: 1389-90. PMID 23613561 DOI: 10.2337/Db13-0196  0.653
2012 Sims E, Evans-Molina C. Stem Cells as a Tool to Improve Outcomes of Islet Transplantation Journal of Transplantation. 2012: 736491-736491. PMID 22970344 DOI: 10.1155/2012/736491  0.39
2012 Shoemaker TJ, Kono T, Mariash CN, Evans-Molina C. Thyroid hormone analogues for the treatment of metabolic disorders: New potential for unmet clinical needs? Endocrine Practice. 18: 954-964. PMID 22784847 DOI: 10.4158/Ep12086.Ra  0.361
2012 Tersey SA, Nishiki Y, Templin AT, Cabrera SM, Stull ND, Colvin SC, Evans-Molina C, Rickus JL, Maier B, Mirmira RG. Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model. Diabetes. 61: 818-27. PMID 22442300 DOI: 10.2337/Db11-1293  0.831
2012 Kono T, Ahn G, Moss DR, Gann L, Zarain-Herzberg A, Nishiki Y, Fueger PT, Ogihara T, Evans-Molina C. PPAR-γ activation restores pancreatic islet SERCA2 levels and prevents β-cell dysfunction under conditions of hyperglycemic and cytokine stress. Molecular Endocrinology (Baltimore, Md.). 26: 257-71. PMID 22240811 DOI: 10.1210/Me.2011-1181  0.488
2012 Evans-Molina C. Diabetes: Mayday, mayday, mayday! Answering the distress call of the β cell Science Translational Medicine. 4. DOI: 10.1126/scitranslmed.3003792  0.402
2010 Gupta D, Kono T, Evans-Molina C. The role of peroxisome proliferator-activated receptor γ in pancreatic β cell function and survival: Therapeutic implications for the treatment of type 2 diabetes mellitus Diabetes, Obesity and Metabolism. 12: 1036-1047. PMID 20977574 DOI: 10.1111/J.1463-1326.2010.01299.X  0.568
2010 Sturek JM, Castle JD, Trace AP, Page LC, Castle AM, Evans-Molina C, Parks JS, Mirmira RG, Hedrick CC. An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells. The Journal of Clinical Investigation. 120: 2575-89. PMID 20530872 DOI: 10.1172/Jci41280  0.658
2010 Ogihara T, Chuang JC, Vestermark GL, Garmey JC, Ketchum RJ, Huang X, Brayman KL, Thorner MO, Repa JJ, Mirmira RG, Evans-Molina C. Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling. The Journal of Biological Chemistry. 285: 5392-404. PMID 20007976 DOI: 10.1074/Jbc.M109.064659  0.628
2009 Evans-Molina C, Vestermark GL, Mirmira RG. Development of insulin-producing cells from primitive biologic precursors. Current Opinion in Organ Transplantation. 14: 56-63. PMID 19337148 DOI: 10.1097/Mot.0B013E3283186Fc1  0.636
2009 Evans-Molina C, Robbins RD, Kono T, Tersey SA, Vestermark GL, Nunemaker CS, Garmey JC, Deering TG, Keller SR, Maier B, Mirmira RG. Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure. Molecular and Cellular Biology. 29: 2053-67. PMID 19237535 DOI: 10.1128/Mcb.01179-08  0.793
2007 Evans-Molina C, Garmey JC, Ketchum R, Brayman KL, Deng S, Mirmira RG. Glucose regulation of insulin gene transcription and pre-mRNA processing in human islets. Diabetes. 56: 827-35. PMID 17327454 DOI: 10.2337/Db06-1440  0.6
2006 Francis J, Babu DA, Deering TG, Chakrabarti SK, Garmey JC, Evans-Molina C, Taylor DG, Mirmira RG. Role of chromatin accessibility in the occupancy and transcription of the insulin gene by the pancreatic and duodenal homeobox factor 1. Molecular Endocrinology (Baltimore, Md.). 20: 3133-45. PMID 16901969 DOI: 10.1210/Me.2006-0126  0.733
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