David Zagzag, MD PhD - Publications

Affiliations: 
Pathology New York University, New York, NY, United States 

175 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Munawar K, Nayak G, Fatterpekar GM, Sen C, Zagzag D, Zan E, Hagiwara M. Cavernous sinus lesions. Clinical Imaging. 68: 71-89. PMID 32574933 DOI: 10.1016/J.Clinimag.2020.06.029  0.359
2020 Cordova C, Syeda MM, Corless B, Wiggins JM, Patel A, Kurz SC, Delara M, Sawaged Z, Utate M, Placantonakis D, Golfinos J, Schafrick J, Silverman JS, Jain R, Snuderl M, ... Zagzag D, et al. Abstract A65: Longitudinal detection of TERT-mutant plasma cell-free circulating tumor DNA in newly diagnosed glioblastoma patients Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Liqbiop20-A65  0.327
2019 Chen H, Thomas C, Munoz FA, Alexandrescu S, Horbinski CM, Olar A, McGuone D, Camelo-Piragua S, Wang L, Pentsova E, Phillips J, Aldape K, Chen W, Iafrate AJ, Chi AS, ... Zagzag D, et al. Polysomy is associated with poor outcome in 1p19q co-deleted oligodendroglial tumors. Neuro-Oncology. PMID 31140557 DOI: 10.1093/Neuonc/Noz098  0.322
2019 Mureb M, Benjamin C, Sen C, Spino M, Krasnozhen-Ratush O, Zagzag D, Pavlick AC, Kondziolka D. Gamma Knife Radiosurgery and Immunotherapy as Primary Treatment for a Malignant Tumor of the Cranial Base beginning as Lentigo Maligna: A Case Report. Practical Radiation Oncology. PMID 31129314 DOI: 10.1016/J.Prro.2019.05.010  0.333
2018 Spino M, Kurz SC, Chiriboga L, Serrano J, Zeck B, Sen N, Patel S, Shen G, Vasudevaraja V, Tsirigos A, Suryadevara CM, Frenster JD, Tateishi K, Wakimoto H, Jain R, ... ... Zagzag D, et al. Cell surface Notch ligand DLL3 is a therapeutic target in isocitrate dehydrogenase mutant glioma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30397180 DOI: 10.1158/1078-0432.Ccr-18-2312  0.338
2018 Snuderl M, Kannan K, Pfaff E, Wang S, Stafford JM, Serrano J, Heguy A, Ray K, Faustin A, Aminova O, Dolgalev I, Stapleton SL, Zagzag D, Chiriboga L, Gardner SL, et al. Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma. Nature Communications. 9: 2868. PMID 30030436 DOI: 10.1038/S41467-018-05029-3  0.324
2018 Katz LM, Hielscher T, Liechty B, Silverman J, Zagzag D, Sen R, Wu P, Golfinos JG, Reuss D, Neidert MC, Wirsching HG, Baumgarten P, Herold-Mende C, Wick W, Harter PN, et al. Loss of histone H3K27me3 identifies a subset of meningiomas with increased risk of recurrence. Acta Neuropathologica. PMID 29627952 DOI: 10.1007/S00401-018-1844-9  0.345
2018 Cui X, Morales RT, Qian W, Wang H, Gagner JP, Dolgalev I, Placantonakis D, Zagzag D, Cimmino L, Snuderl M, Lam RHW, Chen W. Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesis. Biomaterials. 161: 164-178. PMID 29421553 DOI: 10.1016/J.Biomaterials.2018.01.053  0.398
2018 Gagner JP, Lechpammer M, Zagzag D. Induction and Assessment of Hypoxia in Glioblastoma Cells In Vitro. Methods in Molecular Biology (Clifton, N.J.). 1741: 111-123. PMID 29392695 DOI: 10.1007/978-1-4939-7659-1_9  0.345
2018 Kloetgen A, Serrano J, Patel S, Bowman C, Shen G, Zagzag D, Karajannis MA, Golfinos JG, Placantonakis D, Tsirigos A, Chi AS, Snuderl M. Abstract 3658: DNA methylation of circulating tumor educated leukocytes predicts IDH1/2 mutation status in adult patients with diffuse gliomas Cancer Research. 78: 3658-3658. DOI: 10.1158/1538-7445.Am2018-3658  0.361
2018 Gagner J, Kamen S, Nayak S, Serrano J, Vasudevaraja V, Bledea R, Ueberheide B, Snuderl M, Lechpammer M, Zagzag D. GENE-14. DNA METHYLATION AND PROTEOMIC ALTERATIONS IDENTIFY HISTOLOGICALLY-DEFINED TUMOR CELL POPULATIONS AND CHARACTERIZE INTRATUMOR HETEROGENEITY IN GLIOBLASTOMA Neuro-Oncology. 20: vi105-vi105. DOI: 10.1093/Neuonc/Noy148.440  0.346
2017 Bayin NS, Frenster JD, Sen R, Si S, Modrek AS, Galifianakis N, Dolgalev I, Ortenzi V, Illa-Bochaca I, Khahera A, Serrano J, Chiriboga L, Zagzag D, Golfinos JG, Doyle W, et al. Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells. Oncotarget. 8: 64932-64953. PMID 29029402 DOI: 10.18632/Oncotarget.18117  0.391
2017 Gagner JP, Sarfraz Y, Ortenzi V, Alotaibi FM, Chiriboga LA, Tayyib AT, Douglas GJ, Chevalier E, Romagnoli B, Tuffin G, Schmitt M, Lemercier G, Dembowsky K, Zagzag D. Multifaceted C-X-C Chemokine Receptor 4 Inhibition Interferes with Anti-Vascular Endothelial Growth Factor Therapy-Induced Glioma Dissemination. The American Journal of Pathology. PMID 28734730 DOI: 10.1016/J.Ajpath.2017.04.020  0.451
2017 Snuderl M, Zhang G, Wu P, Jennings TS, Shroff S, Ortenzi V, Jain R, Cohen B, Reidy JJ, Dushay MS, Wisoff JH, Harter DH, Karajannis MA, Fenyo D, Neubert TA, ... Zagzag D, et al. Endothelium-Independent Primitive Myxoid Vascularization Creates Invertebrate-Like Channels to Maintain Blood Supply in Optic Gliomas. The American Journal of Pathology. PMID 28606795 DOI: 10.1016/J.Ajpath.2017.04.004  0.332
2017 Mahase S, Rattenni RN, Wesseling P, Leenders W, Baldotto C, Jain R, Zagzag D. Hypoxia-Mediated Mechanisms Associated with Antiangiogenic Treatment Resistance in Glioblastomas. The American Journal of Pathology. PMID 28284719 DOI: 10.1016/J.Ajpath.2017.01.010  0.377
2017 Hainline C, Rucker JC, Zagzag D, Golfinos JG, Lui YW, Liechty B, Warren FA, Balcer LJ, Galetta SL. Tumoral Presentation of Homonymous Hemianopia and Prosopagnosia in Cerebral Amyloid Angiopathy-Related Inflammation. Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. 37: 48-52. PMID 28187081 DOI: 10.1097/Wno.0000000000000474  0.317
2017 Cordova C, Corless B, Syeda M, Patel A, Delara M, Eisele S, Schafrick J, Placantonakis D, Pacione D, Silverman J, Fatterpekar G, Shepherd T, Jain R, Snuderl M, Zagzag D, et al. PATH-42. DETECTION OF TERT MUTATIONS IN CELL-FREE CIRCULATING TUMOR DNA (ctDNA) OF GLIOBLASTOMA PATIENTS USING DROPLET DIGITAL PCR Neuro-Oncology. 19: vi180-vi180. DOI: 10.1093/Neuonc/Nox168.732  0.351
2017 Lechpammer M, Shahlaie K, Girgis F, Gonzales H, Bishop J, Nudler E, Zagzag D. CMET-46. EXPRESSION OF HYDROGEN SULFIDE (H2S) PRODUCING ENZYMES IN METASTATIC BRAIN TUMORS Neuro-Oncology. 19: vi49-vi49. DOI: 10.1093/Neuonc/Nox168.192  0.333
2017 Kader M, Frenster J, Liechty B, Modrek A, Tsirigos A, Golfinos J, Eisele S, Jain R, Shepherd T, Fatterpekar G, MacNeil D, Shohdy N, Huang X, Chi AS, Snuderl M, ... Zagzag D, et al. CBIO-19. CHARACTERIZATION OF GPR133 EXPRESSION IN GLIOMA SUBTYPES Neuro-Oncology. 19: vi36-vi36. DOI: 10.1093/Neuonc/Nox168.138  0.32
2017 Lechpammer M, Tian M, Shahlaie K, Fereidouni F, Harmany ZT, Borowsky AD, Zagzag D, Levenson RM. P03.14 Validation of microscopy with ultraviolet surface excitation - MUSE - imaging of human primary and metastatic brain tumors Neuro-Oncology. 19: iii36-iii36. DOI: 10.1093/Neuonc/Nox036.129  0.335
2016 Bayin NS, Ma L, Thomas C, Baitalmal R, Sure A, Fansiwala K, Bustoros M, Golfinos JG, Pacione D, Snuderl M, Zagzag D, Barcellos-Hoff MH, Placantonakis D. Patient-Specific Screening Using High-Grade Glioma Explants to Determine Potential Radiosensitization by a TGF-β Small Molecule Inhibitor. Neoplasia (New York, N.Y.). 18: 795-805. PMID 27978994 DOI: 10.1016/J.Neo.2016.08.008  0.311
2016 Veyrat M, Durand S, Classe M, Glavan TM, Oker N, Kapetanakis NI, Jiang X, Gelin A, Herman P, Casiraghi O, Zagzag D, Enot D, Busson P, Vérillaud B. Stimulation of the toll-like receptor 3 promotes metabolic reprogramming in head and neck carcinoma cells. Oncotarget. PMID 27791989 DOI: 10.18632/Oncotarget.12892  0.34
2016 Bayin NS, Frenster JD, Kane JR, Rubenstein J, Modrek AS, Baitalmal R, Dolgalev I, Rudzenski K, Scarabottolo L, Crespi D, Redaelli L, Snuderl M, Golfinos JG, Doyle W, Pacione D, ... ... Zagzag D, et al. GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growth. Oncogenesis. 5: e263. PMID 27775701 DOI: 10.1038/oncsis.2016.63  0.353
2016 Bender S, Gronych J, Warnatz H, Hutter B, Gröbner S, Ryzhova M, Pfaff E, Hovestadt V, Weinberg F, Halbach S, Kool M, Northcott PA, Sturm D, Bjerke L, Zichner T, ... ... Zagzag D, et al. Recurrent MET fusion genes represent a drug target in pediatric glioblastoma Nature Medicine. 22: 1314-1320. PMID 27748748 DOI: 10.1038/Nm.4204  0.337
2016 Unruh D, Schwarze SR, Khoury L, Thomas C, Wu M, Chen L, Chen R, Liu Y, Schwartz MA, Amidei C, Kumthekar P, Benjamin CG, Song K, Dawson C, Rispoli JM, ... ... Zagzag D, et al. Mutant IDH1 and thrombosis in gliomas. Acta Neuropathologica. PMID 27664011 DOI: 10.1007/S00401-016-1620-7  0.34
2016 Orillac C, Thomas C, Dastagirzada Y, Hidalgo ET, Golfinos JG, Zagzag D, Wisoff JH, Karajannis MA, Snuderl M. Pilocytic astrocytoma and glioneuronal tumor with histone H3 K27M mutation. Acta Neuropathologica Communications. 4: 84. PMID 27519587 DOI: 10.1186/S40478-016-0361-0  0.376
2016 Cheung V, Segal D, Gardner SL, Zagzag D, Wisoff JH, Allen JC, Karajannis MA. Utility of MRI versus tumor markers for post-treatment surveillance of marker-positive CNS germ cell tumors. Journal of Neuro-Oncology. PMID 27406584 DOI: 10.1007/S11060-016-2207-9  0.416
2016 Lieber B, Han B, Allen J, Fatterpekar G, Agarwal N, Kazemi N, Zagzag D. Utility of positron emission tomography in schwannomatosis. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 26960263 DOI: 10.1016/J.Jocn.2016.01.027  0.313
2016 Kannan KS, Tsirigos A, Serrano J, Forrester LA, Faustin A, Thomas C, Capper D, Hovestadt V, Pfister SM, Jones DTW, Sill M, Schrimpf D, Deimling Av, Heguy A, Gardner SL, ... ... Zagzag D, et al. Abstract 11: Advancing methylation profiling in neuropathology: Diagnosis and clinical management Clinical Cancer Research. 22: 11-11. DOI: 10.1158/1557-3265.Pmsclingen15-11  0.314
2016 Frenster J, Bayin NS, Kane JR, Rubenstein J, Modrek A, Baitamal R, Dolgalev I, Rudzenski K, Snuderl M, Golfinos J, Doyle W, Pacione D, Chi A, Heguy A, Shohdy N, ... ... Zagzag D, et al. STMC-25. GPR133 PROMOTES HYPOXIA-DRIVEN TUMOR PROGRESSION IN GLIOBLASTOMA Neuro-Oncology. 18: vi187-vi188. DOI: 10.1093/Neuonc/Now212.788  0.402
2016 Chen H, Thomas C, Munoz FA, Alexandrescu S, Horbinski C, Olar A, McGuone D, Camelo-Piragua S, Wang L, Pentsova E, Phillips J, Aldape K, Iafrate AJ, Golfinos J, Chi A, ... Zagzag D, et al. MPTH-34. THE PROGNOSTIC VALUE OF POLYSOMY IN OLIGODENDROGLIAL TUMORS Neuro-Oncology. 18: vi113-vi113. DOI: 10.1093/Neuonc/Now212.471  0.358
2015 Shankar GM, Lelic N, Gill CM, Thorner AR, Van Hummelen P, Wisoff JH, Loeffler JS, Brastianos PK, Shin JH, Borges LF, Butler WE, Zagzag D, Brody RI, Duhaime AC, Taylor MD, et al. BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology. Acta Neuropathologica. PMID 26487540 DOI: 10.1007/S00401-015-1492-2  0.317
2015 Jain R, Griffith B, Alotaibi F, Zagzag D, Fine H, Golfinos J, Schultz L. Glioma Angiogenesis and Perfusion Imaging: Understanding the Relationship between Tumor Blood Volume and Leakiness with Increasing Glioma Grade. Ajnr. American Journal of Neuroradiology. PMID 26206809 DOI: 10.3174/Ajnr.A4405  0.358
2015 Pajtler KW, Witt H, Sill M, Jones DT, Hovestadt V, Kratochwil F, Wani K, Tatevossian R, Punchihewa C, Johann P, Reimand J, Warnatz HJ, Ryzhova M, Mack S, Ramaswamy V, ... ... Zagzag D, et al. Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups. Cancer Cell. 27: 728-43. PMID 25965575 DOI: 10.1016/J.Ccell.2015.04.002  0.352
2015 Haber MA, Iranmahboob A, Thomas C, Liu M, Najjar A, Zagzag D. ERG is a novel and reliable marker for endothelial cells in central nervous system tumors. Clinical Neuropathology. 34: 117-27. PMID 25881913 DOI: 10.5414/Np300817  0.435
2015 Wang X, Dubuc AM, Ramaswamy V, Mack S, Gendoo DM, Remke M, Wu X, Garzia L, Luu B, Cavalli F, Peacock J, López B, Skowron P, Zagzag D, Lyden D, et al. Medulloblastoma subgroups remain stable across primary and metastatic compartments. Acta Neuropathologica. 129: 449-57. PMID 25689980 DOI: 10.1007/S00401-015-1389-0  0.368
2015 Gagner J, Sarfraz Y, Alotaibi FM, Ortenzi V, Tayyib AT, Chiriboga LA, Douglas GJ, Chevalier E, Romagnoli B, Tuffin G, Dembowsky K, Zagzag D. Abstract A20: A novel CXCR4 antagonist interferes with antivascular endothelial growth factor therapy-induced glioma dissemination Brain. 75. DOI: 10.1158/1538-7445.Brain15-A20  0.403
2015 Snuderl M, Kannan K, Aminova O, Dolgalev I, Heguy A, Faustin A, Zagzag D, Gardner SL, Allen JC, Wisoff JH, Capper D, Hovestadt V, Ahsan S, Eberhart C, Pfister SM, et al. Abstract LB-172: Novel candidate oncogenic drivers in pineoblastoma Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-172  0.365
2015 Zagzag D, Gagner J, Ortenzi V, Bayin NS, Sarfraz Y, Chiriboga L, Placantonakis D. TMIC-19HYPOXIA-INDUCIBLE GENE (HIG2) AND PERILIPIN 2 ARE SPECIFIC BIOMARKERS OF HYPOXIC TUMOR CELLS IN GLIOMA AND STROMAL CELLS IN CNS HEMANGIOBLASTOMA Neuro-Oncology. 17: v218.7-v. DOI: 10.1093/Neuonc/Nov236.19  0.47
2015 Schwarze S, Khoury L, Thomas C, Benjamin C, Chen R, Chen L, Liu Y, Song K, Dawson C, Pacione D, Zagzag D, McIntyre T, Snuderl M, Horbinski C. TMIC-13MUTANTIDH1/2SUPPRESSES LOCAL AND SYSTEMIC THROMBOSIS IN GLIOMA PATIENTS Neuro-Oncology. 17: v217.5-v217. DOI: 10.1093/Neuonc/Nov236.13  0.359
2015 Bayin NS, Kane JR, Modrek AS, Shohdy N, MacNeil D, Zagzag D, Placantonakis DG. STEM-05GPR133 IS ENRICHED IN GLIOBLASTOMA STEM CELLS AND REGULATES THE RESPONSE TO HYPOXIA Neuro-Oncology. 17: v209.1-v209. DOI: 10.1093/Neuonc/Nov234.05  0.373
2015 Bayin NS, Sen R, Si S, Modrek AS, Ortenzi V, Zagzag D, Snuderl M, Golfinos JG, Doyle W, Galifianakis N, Chesler M, Illa-Bochaca I, Barcellos-Hoff MH, Dolgalev I, Heguy A, et al. STEM-04DEFINING GLIOBLASTOMA STEM CELL HETEROGENEITY Neuro-Oncology. 17: v208.4-v209. DOI: 10.1093/Neuonc/Nov234.04  0.411
2015 Karajannis M, Kannan K, Aminova O, Dolgalev I, Heguy A, Faustin A, Zagzag D, Gardner S, Allen J, Wisoff J, Capper D, Hovestadt V, Ahsan S, Eberhart C, Pfister S, et al. GENO-20NOVEL CANDIDATE ONCOGENIC DRIVERS IN PINEOBLASTOMA Neuro-Oncology. 17: v95.4-v96. DOI: 10.1093/Neuonc/Nov215.20  0.37
2015 Snuderl M, Kannan K, Aminova O, Dolgalev I, Heguy A, Faustin A, Zagzag D, Gardner S, Allen J, Wisoff J, Capper D, Hovestadt V, Ahsan S, Eberhart C, Pfister S, et al. MB-17 * NOVEL CANDIDATE ONCOGENIC DRIVERS IN PINEOBLASTOMA Neuro-Oncology. 17: iii23-iii23. DOI: 10.1093/Neuonc/Nov061.93  0.362
2014 Li W, Cooper J, Zhou L, Yang C, Erdjument-Bromage H, Zagzag D, Snuderl M, Ladanyi M, Hanemann CO, Zhou P, Karajannis MA, Giancotti FG. Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus. Cancer Cell. 26: 48-60. PMID 25026211 DOI: 10.1016/J.Ccr.2014.05.001  0.352
2014 Takano N, Sarfraz Y, Gilkes DM, Chaturvedi P, Xiang L, Suematsu M, Zagzag D, Semenza GL. Decreased expression of cystathionine β-synthase promotes glioma tumorigenesis. Molecular Cancer Research : McR. 12: 1398-406. PMID 24994751 DOI: 10.1158/1541-7786.Mcr-14-0184  0.396
2014 Buczkowicz P, Hoeman C, Rakopoulos P, Pajovic S, Letourneau L, Dzamba M, Morrison A, Lewis P, Bouffet E, Bartels U, Zuccaro J, Agnihotri S, Ryall S, Barszczyk M, Chornenkyy Y, ... ... Zagzag D, et al. Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations. Nature Genetics. 46: 451-6. PMID 24705254 DOI: 10.1038/Ng.2936  0.34
2014 Ruppe V, Dilsiz P, Reiss CS, Carlson C, Devinsky O, Zagzag D, Weiner HL, Talos DM. Developmental brain abnormalities in tuberous sclerosis complex: a comparative tissue analysis of cortical tubers and perituberal cortex. Epilepsia. 55: 539-50. PMID 24512506 DOI: 10.1111/Epi.12545  0.31
2014 Jones DTW, Capper D, Sill M, Hovestadt V, Schweizer L, Fischer R, Schick M, Bewerunge-Hudler M, Benner A, Zagzag D, Lichter P, Karajannis MA, Aldape KD, Korshunov A, Deimling Av, et al. Abstract 1889: Next-generation neuropathology - Improving diagnostic accuracy for brain tumors using DNA methylation array-based molecular profiling Cancer Research. 74: 1889-1889. DOI: 10.1158/1538-7445.Am2014-1889  0.342
2014 Sumru Bayin N, Si S, Modrek A, Song H, Zagzag D, Hoang DM, Wadghiri YZ, Dolgalev I, Baysan M, Heguy A, Barcellos-Hoff MH, Placantonakis D. SC-04 * NON-UNIFORM NOTCH SIGNALING UNDERLIES HETEROGENEITY WITHIN THE GLIOBLASTOMA STEM CELL POPULATION Neuro-Oncology. 16: v197-v197. DOI: 10.1093/Neuonc/Nou275.4  0.35
2014 Sarfraz Y, Alotaibi FM, Ortenzi V, Tayyib AT, Douglas GJ, Chevalier E, Romagnoli B, Tuffin G, Gagner J, Zagzag D. ET-51 * COMBINED THERAPY WITH A NOVEL CXCR4 ANTAGONIST AND AN ANTI-VEGF ANTIBODY IMPAIRS THE GROWTH OF GLIOMAS Neuro-Oncology. 16: v90-v90. DOI: 10.1093/Neuonc/Nou255.48  0.383
2014 Jones DTW, Capper D, Sill M, Hovestadt V, Lichter P, Zagzag D, Karajannis MA, Aldape KD, Korshunov A, Deimling Av, Pfister SM. Next-Generation Neuropathology - Improving Diagnostic Accuracy For Brain Tumors Using Dna Methylation Array-Based Molecular Profiling Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou206.13  0.353
2013 Hütt-Cabezas M, Karajannis MA, Zagzag D, Shah S, Horkayne-Szakaly I, Rushing EJ, Cameron JD, Jain D, Eberhart CG, Raabe EH, Rodriguez FJ. Activation of mTORC1/mTORC2 signaling in pediatric low-grade glioma and pilocytic astrocytoma reveals mTOR as a therapeutic target. Neuro-Oncology. 15: 1604-14. PMID 24203892 DOI: 10.1093/Neuonc/Not132  0.345
2013 Esencay M, Sarfraz Y, Zagzag D. CXCR7 is induced by hypoxia and mediates glioma cell migration towards SDF-1α. Bmc Cancer. 13: 347. PMID 23865743 DOI: 10.1186/1471-2407-13-347  0.801
2013 Laviv Y, Zagzag D, Fichman-Horn S, Michowitz S. Primary central nervous system histiocytic sarcoma. Brain Tumor Pathology. 30: 192-5. PMID 23135612 DOI: 10.1007/S10014-012-0123-Z  0.348
2013 Narayana A, Tam MM, Gruber DB, Golfinos J, Parker E, Zagzag D, Gruber ML. A phase II trial of lithium, bevacizumab, temozolomide, and radiation for newly diagnosed glioblastomas (GBM). Journal of Clinical Oncology. 31. DOI: 10.1200/Jco.2013.31.15_Suppl.E13033  0.345
2012 Raz E, Zagzag D, Saba L, Mannelli L, Di Paolo PL, D'Ambrosio F, Knopp E. Cyst with a mural nodule tumor of the brain. Cancer Imaging : the Official Publication of the International Cancer Imaging Society. 12: 237-44. PMID 22935908 DOI: 10.1102/1470-7330.2012.0028  0.382
2012 Hardee ME, Zagzag D. Mechanisms of glioma-associated neovascularization. The American Journal of Pathology. 181: 1126-41. PMID 22858156 DOI: 10.1016/J.Ajpath.2012.06.030  0.367
2012 Singh D, Chan JM, Zoppoli P, Niola F, Sullivan R, Castano A, Liu EM, Reichel J, Porrati P, Pellegatta S, Qiu K, Gao Z, Ceccarelli M, Riccardi R, Brat DJ, ... ... Zagzag D, et al. Transforming fusions of FGFR and TACC genes in human glioblastoma. Science (New York, N.Y.). 337: 1231-5. PMID 22837387 DOI: 10.1126/Science.1220834  0.334
2012 Hardee ME, Marciscano AE, Medina-Ramirez CM, Zagzag D, Narayana A, Lonning SM, Barcellos-Hoff MH. Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β. Cancer Research. 72: 4119-29. PMID 22693253 DOI: 10.1158/0008-5472.Can-12-0546  0.389
2012 Wu X, Northcott PA, Dubuc A, Dupuy AJ, Shih DJ, Witt H, Croul S, Bouffet E, Fults DW, Eberhart CG, Garzia L, Van Meter T, Zagzag D, Jabado N, Schwartzentruber J, et al. Clonal selection drives genetic divergence of metastatic medulloblastoma. Nature. 482: 529-33. PMID 22343890 DOI: 10.1038/Nature10825  0.301
2012 Lin A, Rodriguez FJ, Karajannis MA, Williams SC, Legault G, Zagzag D, Burger PC, Allen JC, Eberhart CG, Bar EE. BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants. Journal of Neuropathology and Experimental Neurology. 71: 66-72. PMID 22157620 DOI: 10.1097/Nen.0B013E31823F2Cb0  0.416
2012 Narayana A, Gruber D, Kunnakkat S, Golfinos JG, Parker E, Raza S, Zagzag D, Eagan P, Gruber ML. A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma. Journal of Neurosurgery. 116: 341-5. PMID 22035272 DOI: 10.3171/2011.9.Jns11656  0.307
2012 Goldenberg DM, Zagzag D, Heselmeyer-Haddad KM, Berroa Garcia LY, Ried T, Loo M, Chang CH, Gold DV. Horizontal transmission and retention of malignancy, as well as functional human genes, after spontaneous fusion of human glioblastoma and hamster host cells in vivo. International Journal of Cancer. Journal International Du Cancer. 131: 49-58. PMID 21796629 DOI: 10.1002/Ijc.26327  0.381
2012 Narayana A, Kunnakkat SD, Medabalmi P, Golfinos J, Parker E, Knopp E, Zagzag D, Eagan P, Gruber D, Gruber ML. Change in pattern of relapse after antiangiogenic therapy in high-grade glioma. International Journal of Radiation Oncology, Biology, Physics. 82: 77-82. PMID 21163583 DOI: 10.1016/J.Ijrobp.2010.10.038  0.31
2012 Kozono D, Nitta M, Sampetrean O, Kimberly N, Kushwaha D, Merzon D, Ligon K, Zhu S, Zhu K, Kim TH, Kwon C, Becher O, Saya H, Chen CC, Donovan LK, ... ... Zagzag D, et al. LAB-STEM CELLS Neuro-Oncology. 14: vi142-vi152. DOI: 10.1093/Neuonc/Nos239  0.752
2012 Proescholdt MA, Merrill MJ, Stoerr E, Lohmeier A, Brawanski A, Sim H, Hu B, Pineda CA, Yoon S, Viapiano MS, Rajappa P, Cobb WS, Huang Y, Lyden DC, Bromberg J, ... ... Zagzag D, ... ... Zagzag D, ... ... Zagzag D, et al. LAB-ANGIOGENESIS AND INVASION Neuro-Oncology. 14: vi1-vi6. DOI: 10.1093/Neuonc/Nos219  0.78
2011 Narayana A, Perretta D, Kunnakkat S, Gruber D, Golfinos J, Parker E, Medabalmi P, Zagzag D, Pat Eagan RN, Gruber M. Invasion is not an independent prognostic factor in high-grade glioma. Journal of Cancer Research and Therapeutics. 7: 331-5. PMID 22044816 DOI: 10.4103/0973-1482.87039  0.333
2011 Lee S, Cimica V, Ramachandra N, Zagzag D, Kalpana GV. Aurora A is a repressed effector target of the chromatin remodeling protein INI1/hSNF5 required for rhabdoid tumor cell survival. Cancer Research. 71: 3225-35. PMID 21521802 DOI: 10.1158/0008-5472.Can-10-2167  0.453
2011 Williams SC, Karajannis MA, Chiriboga L, Golfinos JG, von Deimling A, Zagzag D. R132H-mutation of isocitrate dehydrogenase-1 is not sufficient for HIF-1α upregulation in adult glioma. Acta Neuropathologica. 121: 279-81. PMID 21181477 DOI: 10.1007/S00401-010-0790-Y  0.371
2011 Smith ME, Cimica V, Chinni S, Jana S, Koba W, Yang Z, Fine E, Zagzag D, Montagna C, Kalpana GV. Therapeutically targeting cyclin D1 in primary tumors arising from loss of Ini1. Proceedings of the National Academy of Sciences of the United States of America. 108: 319-24. PMID 21173237 DOI: 10.1073/Pnas.0913297108  0.407
2011 Sethi R, Allen J, Donahue B, Karajannis M, Gardner S, Wisoff J, Kunnakkat S, Mathew J, Zagzag D, Newman K, Narayana A. Prospective neuraxis MRI surveillance reveals a high risk of leptomeningeal dissemination in diffuse intrinsic pontine glioma. Journal of Neuro-Oncology. 102: 121-7. PMID 20623246 DOI: 10.1007/S11060-010-0301-Y  0.3
2011 Hardee ME, Marciscano AE, Esencay M, Zagzag D, Barcellos-Hoff MH. Abstract LB-361: Radiosensitization and decreased neurosphere-forming capacity with TGFβ inhibition in glioma cells Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-361  0.78
2011 Hardee M, Marciscano A, Zagzag D, Narayana A, Barcellos-Hoff M. TGFβ Inhibition Radiosensitizes Murine Glioblastoma Cells and Decreases Neurosphere-forming Capacity International Journal of Radiation Oncology*Biology*Physics. 81: S714. DOI: 10.1016/J.Ijrobp.2011.06.1268  0.361
2010 Bollo RJ, Zagzag D, Samadani U. Synchronous choroid plexus papilloma of the fourth ventricle and ependymoma of the filum terminale: case report. Neurosurgery. 67: E1454-9; discussion . PMID 20871433 DOI: 10.1227/Neu.0B013E3181F35144  0.339
2010 Chen GJ, Karajannis MA, Newcomb EW, Zagzag D. Overexpression and activation of epidermal growth factor receptor in hemangioblastomas. Journal of Neuro-Oncology. 99: 195-200. PMID 20730556 DOI: 10.1007/S11060-010-0125-9  0.364
2010 Méndez O, Zavadil J, Esencay M, Lukyanov Y, Santovasi D, Wang SC, Newcomb EW, Zagzag D. Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres. Molecular Cancer. 9: 133. PMID 20515450 DOI: 10.1186/1476-4598-9-133  0.795
2010 Ammoun S, Cunliffe CH, Allen JC, Chiriboga L, Giancotti FG, Zagzag D, Hanemann CO, Karajannis MA. ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma. Neuro-Oncology. 12: 834-43. PMID 20511180 DOI: 10.1093/Neuonc/Noq012  0.313
2010 Newcomb EW, Lukyanov Y, Kawashima N, Alonso-Basanta M, Wang SC, Liu M, Jure-Kunkel M, Zagzag D, Demaria S, Formenti SC. Radiotherapy enhances antitumor effect of anti-CD137 therapy in a mouse Glioma model. Radiation Research. 173: 426-32. PMID 20334514 DOI: 10.1667/Rr1904.1  0.374
2010 Esencay M, Newcomb EW, Zagzag D. HGF upregulates CXCR4 expression in gliomas via NF-kappaB: implications for glioma cell migration. Journal of Neuro-Oncology. 99: 33-40. PMID 20157762 DOI: 10.1007/S11060-010-0111-2  0.792
2010 Caseiras GB, Chheang S, Babb J, Rees JH, Pecerrelli N, Tozer DJ, Benton C, Zagzag D, Johnson G, Waldman AD, Jäger HR, Law M. Relative cerebral blood volume measurements of low-grade gliomas predict patient outcome in a multi-institution setting. European Journal of Radiology. 73: 215-20. PMID 19201123 DOI: 10.1016/J.Ejrad.2008.11.005  0.313
2010 Narayana A, Kunnakkat S, Medabalmi P, Golfinos J, Parker E, Knopp E, Zagzag D, Gruber D, Gruber ML. Abstract 5336: Change in pattern of relapse following anti-angiogenic therapy in high grade gliomas Cancer Research. 70: 5336-5336. DOI: 10.1158/1538-7445.Am10-5336  0.339
2010 Wu X, Collier L, Northcott P, Dubuc A, Eberhart C, Meter TV, Zagzag D, Croul S, Dupuy A, Scheetz TE, Scherer S, Bouffet E, Weiss WA, Largaespada DAD, Taylor MD. Abstract 4350: Clonal selection and parallel evolution during leptomeningeal dissemination of human and mouse medulloblastoma result in bicompartmental disease Cancer Research. 70: 4350-4350. DOI: 10.1158/1538-7445.Am10-4350  0.383
2009 Bollo RJ, Berliner JL, Fischer I, Miles DK, Thiele EA, Zagzag D, Weiner HL. Extraventricular subependymal giant cell tumor in a child with tuberous sclerosis complex. Journal of Neurosurgery. Pediatrics. 4: 85-90. PMID 19569916 DOI: 10.3171/2009.3.Peds08225  0.583
2009 Buonamici S, Trimarchi T, Ruocco MG, Reavie L, Cathelin S, Mar BG, Klinakis A, Lukyanov Y, Tseng JC, Sen F, Gehrie E, Li M, Newcomb E, Zavadil J, Meruelo D, ... ... Zagzag D, et al. CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia. Nature. 459: 1000-4. PMID 19536265 DOI: 10.1038/Nature08020  0.32
2009 Barcellos-Hoff MH, Newcomb EW, Zagzag D, Narayana A. Therapeutic targets in malignant glioblastoma microenvironment. Seminars in Radiation Oncology. 19: 163-70. PMID 19464631 DOI: 10.1016/J.Semradonc.2009.02.004  0.377
2009 Cunliffe CH, Fischer I, Monoky D, Law M, Revercomb C, Elrich S, Kopp MJ, Zagzag D. Intracranial lesions mimicking neoplasms. Archives of Pathology & Laboratory Medicine. 133: 101-23. PMID 19123722 DOI: 10.1043/1543-2165-133.1.101  0.551
2009 Cunliffe CH, Fischer I, Karajannis M, Monoky D, Allen J, Wisoff J, Zagzag D. Synchronous mixed germ cell tumor of the pineal gland and suprasellar region with a predominant angiomatous component: a diagnostic challenge. Journal of Neuro-Oncology. 93: 269-74. PMID 19099195 DOI: 10.1007/S11060-008-9770-7  0.598
2009 Narayana A, Kelly P, Golfinos J, Parker E, Johnson G, Knopp E, Zagzag D, Fischer I, Raza S, Medabalmi P, Eagan P, Gruber ML. Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: impact on local control and patient survival. Journal of Neurosurgery. 110: 173-80. PMID 18834263 DOI: 10.3171/2008.4.17492  0.565
2008 Narayana A, Raza S, Golfinos JG, Johnson G, Knopp EA, Zagzag D, Fischer I, Medabalmi P, Eagan P, Gruber ML. Bevacizumab therapy in recurrent high grade glioma: Impact on local control and survival. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 13000. PMID 27951246 DOI: 10.1200/Jco.2008.26.15_Suppl.13000  0.368
2008 Shah PN, Kumar VA, Jung E, Knopp EA, Babb JS, Johnson G, Gruber ML, Zagzag D, Raza S, Narayana A. Comparison of dynamic susceptibility contrast MRI with conventional MRI in evaluating tumor response following bevacizumab therapy in recurrent high-grade gliomas. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 2085. PMID 27948042 DOI: 10.1200/Jco.2008.26.15_Suppl.2085  0.411
2008 Narayana A, Golfinos JG, Fischer I, Raza S, Kelly P, Parker E, Knopp EA, Medabalmi P, Zagzag D, Eagan P, Gruber ML. Feasibility of using bevacizumab with radiation therapy and temozolomide in newly diagnosed high-grade glioma. International Journal of Radiation Oncology, Biology, Physics. 72: 383-9. PMID 18793954 DOI: 10.1016/J.Ijrobp.2008.05.062  0.589
2008 Fischer I, Cunliffe CH, Bollo RJ, Raza S, Monoky D, Chiriboga L, Parker EC, Golfinos JG, Kelly PJ, Knopp EA, Gruber ML, Zagzag D, Narayana A. High-grade glioma before and after treatment with radiation and Avastin: initial observations. Neuro-Oncology. 10: 700-8. PMID 18697955 DOI: 10.1215/15228517-2008-042  0.591
2008 Newcomb EW, Lukyanov Y, Alonso-Basanta M, Esencay M, Smirnova I, Schnee T, Shao Y, Devitt ML, Zagzag D, McBride W, Formenti SC. Antiangiogenic effects of noscapine enhance radioresponse for GL261 tumors. International Journal of Radiation Oncology, Biology, Physics. 71: 1477-84. PMID 18640497 DOI: 10.1016/J.Ijrobp.2008.04.020  0.787
2008 Zagzag D, Esencay M, Mendez O, Yee H, Smirnova I, Huang Y, Chiriboga L, Lukyanov E, Liu M, Newcomb EW. Hypoxia- and vascular endothelial growth factor-induced stromal cell-derived factor-1alpha/CXCR4 expression in glioblastomas: one plausible explanation of Scherer's structures. The American Journal of Pathology. 173: 545-60. PMID 18599607 DOI: 10.2353/Ajpath.2008.071197  0.791
2008 Newcomb EW, Lukyanov Y, Smirnova I, Schnee T, Zagzag D. Noscapine induces apoptosis in human glioma cells by an apoptosis-inducing factor-dependent pathway. Anti-Cancer Drugs. 19: 553-63. PMID 18525314 DOI: 10.1097/Cad.0B013E3282Ffd68D  0.32
2008 Law M, Young RJ, Babb JS, Peccerelli N, Chheang S, Gruber ML, Miller DC, Golfinos JG, Zagzag D, Johnson G. Gliomas: predicting time to progression or survival with cerebral blood volume measurements at dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging. Radiology. 247: 490-8. PMID 18349315 DOI: 10.1148/Radiol.2472070898  0.489
2008 Zhang JG, Kruse CA, Driggers L, Hoa N, Wisoff J, Allen JC, Zagzag D, Newcomb EW, Jadus MR. Tumor antigen precursor protein profiles of adult and pediatric brain tumors identify potential targets for immunotherapy. Journal of Neuro-Oncology. 88: 65-76. PMID 18259692 DOI: 10.1007/S11060-008-9534-4  0.41
2008 Lu H, Pollack E, Young R, Babb JS, Johnson G, Zagzag D, Carson R, Jensen JH, Helpern JA, Law M. Predicting grade of cerebral glioma using vascular-space occupancy MR imaging. Ajnr. American Journal of Neuroradiology. 29: 373-8. PMID 17974612 DOI: 10.3174/Ajnr.A0794  0.394
2007 Lui YW, Law M, Chacko-Mathew J, Babb JS, Tuvia K, Allen JC, Zagzag D, Johnson G. Brainstem corticospinal tract diffusion tensor imaging in patients with primary posterior fossa neoplasms stratified by tumor type: a study of association with motor weakness and outcome. Neurosurgery. 61: 1199-207; discussion. PMID 18162899 DOI: 10.1227/01.Neu.0000306098.38141.81  0.33
2007 Morozov A, Lee SJ, Zhang ZK, Cimica V, Zagzag D, Kalpana GV. INI1 induces interferon signaling and spindle checkpoint in rhabdoid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 4721-30. PMID 17699849 DOI: 10.1158/1078-0432.Ccr-07-0054  0.425
2007 Newcomb EW, Lukyanov Y, Schnee T, Esencay M, Fischer I, Hong D, Shao Y, Zagzag D. The geldanamycin analogue 17-allylamino-17-demethoxygeldanamycin inhibits the growth of GL261 glioma cells in vitro and in vivo. Anti-Cancer Drugs. 18: 875-82. PMID 17667592 DOI: 10.1097/Cad.0B013E3281430Df8  0.777
2007 Law M, Brodsky JE, Babb J, Rosenblum M, Miller DC, Zagzag D, Gruber ML, Johnson G. High cerebral blood volume in human gliomas predicts deletion of chromosome 1p: Preliminary results of molecular studies in gliomas with elevated perfusion. Journal of Magnetic Resonance Imaging : Jmri. 25: 1113-9. PMID 17520715 DOI: 10.1002/Jmri.20920  0.486
2007 Nomura N, Nomura M, Newcomb EW, Zagzag D. Geldanamycin induces G2 arrest in U87MG glioblastoma cells through downregulation of Cdc2 and cyclin B1. Biochemical Pharmacology. 73: 1528-36. PMID 17324379 DOI: 10.1016/J.Bcp.2007.01.022  0.3
2007 Narayana A, Chheang S, Knopp E, Peccerelli N, Babb J, Johnson G, Gruber M, Allen J, Zagzag D, Law M. Comparing cerebral blood volume and vascular permeability measurements with tumor volume measurements following anti-angiogenesis therapy in recurrent gliomas Journal of Clinical Oncology. 25: 2030-2030. DOI: 10.1200/Jco.2007.25.18_Suppl.2030  0.397
2007 Zagzag D. Russell and Rubinstein's Pathology of Tumors of the Nervous System (7th edition) Journal of Neuropathology and Experimental Neurology. 66: 1154. DOI: 10.1097/Nen.0B013E31815D8C5C  0.365
2006 Zagzag D, Lukyanov Y, Lan L, Ali MA, Esencay M, Mendez O, Yee H, Voura EB, Newcomb EW. Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 1221-32. PMID 17075581 DOI: 10.1038/Labinvest.3700482  0.799
2006 Newcomb EW, Demaria S, Lukyanov Y, Shao Y, Schnee T, Kawashima N, Lan L, Dewyngaert JK, Zagzag D, McBride WH, Formenti SC. The combination of ionizing radiation and peripheral vaccination produces long-term survival of mice bearing established invasive GL261 gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4730-7. PMID 16899624 DOI: 10.1158/1078-0432.Ccr-06-0593  0.4
2006 Law M, Oh S, Johnson G, Babb JS, Zagzag D, Golfinos J, Kelly PJ. Perfusion magnetic resonance imaging predicts patient outcome as an adjunct to histopathology: a second reference standard in the surgical and nonsurgical treatment of low-grade gliomas. Neurosurgery. 58: 1099-107; discussion. PMID 16723889 DOI: 10.1227/01.Neu.0000215944.81730.18  0.379
2006 Krishnamachary B, Zagzag D, Nagasawa H, Rainey K, Okuyama H, Baek JH, Semenza GL. Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B. Cancer Research. 66: 2725-31. PMID 16510593 DOI: 10.1158/0008-5472.Can-05-3719  0.368
2006 Law M, Oh S, Babb JS, Wang E, Inglese M, Zagzag D, Knopp EA, Johnson G. Low-grade gliomas: dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging--prediction of patient clinical response. Radiology. 238: 658-67. PMID 16396838 DOI: 10.1148/Radiol.2382042180  0.365
2006 Newcomb EW, Lymberis SC, Lukyanov Y, Shao Y, Schnee T, Devitt M, Rosenstein BS, Zagzag D, Formenti SC. Radiation sensitivity of GL261 murine glioma model and enhanced radiation response by flavopiridol. Cell Cycle (Georgetown, Tex.). 5: 93-9. PMID 16319534 DOI: 10.4161/Cc.5.1.2271  0.434
2006 Newcomb EW, Lukyanov Y, Schnee T, Ali MA, Lan L, Zagzag D. Noscapine inhibits hypoxia-mediated HIF-1α expression andangiogenesis in vitro: a novel function for an old drug International Journal of Oncology. 28: 1121-1130. DOI: 10.3892/Ijo.28.5.1121  0.395
2005 Gagner JP, Law M, Fischer I, Newcomb EW, Zagzag D. Angiogenesis in gliomas: imaging and experimental therapeutics. Brain Pathology (Zurich, Switzerland). 15: 342-63. PMID 16389946 DOI: 10.1111/J.1750-3639.2005.Tb00119.X  0.603
2005 Fischer I, Gagner JP, Law M, Newcomb EW, Zagzag D. Angiogenesis in gliomas: biology and molecular pathophysiology. Brain Pathology (Zurich, Switzerland). 15: 297-310. PMID 16389942 DOI: 10.1111/J.1750-3639.2005.Tb00115.X  0.635
2005 Tsikitis M, Zhang Z, Edelman W, Zagzag D, Kalpana GV. Genetic ablation of Cyclin D1 abrogates genesis of rhabdoid tumors resulting from Ini1 loss. Proceedings of the National Academy of Sciences of the United States of America. 102: 12129-34. PMID 16099835 DOI: 10.1073/Pnas.0505300102  0.37
2005 Newcomb EW, Ali MA, Schnee T, Lan L, Lukyanov Y, Fowkes M, Miller DC, Zagzag D. Flavopiridol downregulates hypoxia-mediated hypoxia-inducible factor-1alpha expression in human glioma cells by a proteasome-independent pathway: implications for in vivo therapy. Neuro-Oncology. 7: 225-35. PMID 16053697 DOI: 10.1215/S1152851704000997  0.752
2005 Zagzag D, Krishnamachary B, Yee H, Okuyama H, Chiriboga L, Ali MA, Melamed J, Semenza GL. Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor. Cancer Research. 65: 6178-88. PMID 16024619 DOI: 10.1158/0008-5472.Can-04-4406  0.385
2005 Zagzag D, Salnikow K, Chiriboga L, Yee H, Lan L, Ali MA, Garcia R, Demaria S, Newcomb EW. Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain. Laboratory Investigation; a Journal of Technical Methods and Pathology. 85: 328-41. PMID 15716863 DOI: 10.1038/Labinvest.3700233  0.405
2004 Nomura M, Nomura N, Newcomb EW, Lukyanov Y, Tamasdan C, Zagzag D. Geldanamycin induces mitotic catastrophe and subsequent apoptosis in human glioma cells. Journal of Cellular Physiology. 201: 374-84. PMID 15389545 DOI: 10.1002/Jcp.20090  0.371
2004 Challa VR, Moody DM, Brown WR, Zagzag D. A morphologic study of the vasculature of malignant gliomas using thick celloidin sections and alkaline phosphatase stain. Clinical Neuropathology. 23: 167-72. PMID 15328881 DOI: 10.1097/00005072-199905000-00123  0.411
2004 Lu S, Ahn D, Johnson G, Law M, Zagzag D, Grossman RI. Diffusion-tensor MR imaging of intracranial neoplasia and associated peritumoral edema: introduction of the tumor infiltration index. Radiology. 232: 221-8. PMID 15220505 DOI: 10.1148/Radiol.2321030653  0.395
2004 Dhodapkar KM, Cirignano B, Chamian F, Zagzag D, Miller DC, Finlay JL, Steinman RM. Invariant natural killer T cells are preserved in patients with glioma and exhibit antitumor lytic activity following dendritic cell-mediated expansion. International Journal of Cancer. Journal International Du Cancer. 109: 893-9. PMID 15027123 DOI: 10.1002/Ijc.20050  0.57
2004 Newcomb EW, Tamasdan C, Entzminger Y, Arena E, Schnee T, Kim M, Crisan D, Lukyanov Y, Miller DC, Zagzag D. Flavopiridol inhibits the growth of GL261 gliomas in vivo: implications for malignant glioma therapy. Cell Cycle (Georgetown, Tex.). 3: 230-4. PMID 14712094 DOI: 10.4161/Cc.3.2.667  0.591
2004 Sorin A, Fishman AJ, Roland JT, Golfinos JG, Lalwani AK, Zagzag D. Immunohistochemical Detection of Hypoxia-Induced Factor-Alpha in Endolymphatic Sac Tumors Otolaryngology–Head and Neck Surgery. 131: P158-P158. DOI: 10.1016/J.Otohns.2004.06.270  0.407
2003 Kleinman GM, Zagzag D, Miller DC. Epithelioid ependymoma: a new variant of ependymoma: report of three cases. Neurosurgery. 53: 743-7; discussion 74. PMID 12943590 DOI: 10.1227/01.Neu.0000079628.55729.12  0.558
2003 Hukin J, Siffert J, Cohen H, Velasquez L, Zagzag D, Allen J. Leptomeningeal dissemination at diagnosis of pediatric low-grade neuroepithelial tumors. Neuro-Oncology. 5: 188-96. PMID 12816725 DOI: 10.1215/S1152851702000297  0.333
2003 Zagzag D, Nomura M, Friedlander DR, Blanco CY, Gagner JP, Nomura N, Newcomb EW. Geldanamycin inhibits migration of glioma cells in vitro: a potential role for hypoxia-inducible factor (HIF-1alpha) in glioma cell invasion. Journal of Cellular Physiology. 196: 394-402. PMID 12811834 DOI: 10.1002/Jcp.10306  0.418
2003 Newcomb EW, Tamasdan C, Entzminger Y, Alonso J, Friedlander D, Crisan D, Miller DC, Zagzag D. Flavopiridol induces mitochondrial-mediated apoptosis in murine glioma GL261 cells via release of cytochrome c and apoptosis inducing factor. Cell Cycle (Georgetown, Tex.). 2: 243-50. PMID 12734434 DOI: 10.4161/Cc.2.3.357  0.522
2003 Cha S, Johnson G, Wadghiri YZ, Jin O, Babb J, Zagzag D, Turnbull DH. Dynamic, contrast-enhanced perfusion MRI in mouse gliomas: correlation with histopathology. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 49: 848-55. PMID 12704767 DOI: 10.1002/Mrm.10446  0.344
2003 Zagzag D, Blanco C, Friedlander DR, Miller DC, Newcomb EW. Expression of p27KIP1 in human gliomas: relationship between tumor grade, proliferation index, and patient survival. Human Pathology. 34: 48-53. PMID 12605366 DOI: 10.1053/Hupa.2003.54  0.591
2003 Zagzag D, Miller DC, Chiriboga L, Yee H, Newcomb EW. Green fluorescent protein immunohistochemistry as a novel experimental tool for the detection of glioma cell invasion in vivo. Brain Pathology (Zurich, Switzerland). 13: 34-7. PMID 12580543 DOI: 10.1111/J.1750-3639.2003.Tb00004.X  0.567
2002 Koutcher JA, Hu X, Xu S, Gade TP, Leeds N, Zhou XJ, Zagzag D, Holland EC. MRI of mouse models for gliomas shows similarities to humans and can be used to identify mice for preclinical trials. Neoplasia (New York, N.Y.). 4: 480-5. PMID 12407441 DOI: 10.1038/Sj.Neo.7900269  0.372
2002 Hukin J, Siffert J, Velasquez L, Zagzag D, Allen J. Leptomeningeal dissemination in children with progressive low-grade neuroepithelial tumors. Neuro-Oncology. 4: 253-60. PMID 12356355 DOI: 10.1093/Neuonc/4.4.253  0.371
2002 Hummel P, Benjamin V, Zagzag D. March 2002: 28-year-old woman with neck and back pain. Brain Pathology (Zurich, Switzerland). 12: 395-7. PMID 12146809 DOI: 10.1111/J.1750-3639.2002.Tb00455.X  0.33
2002 Zhang ZK, Davies KP, Allen J, Zhu L, Pestell RG, Zagzag D, Kalpana GV. Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5. Molecular and Cellular Biology. 22: 5975-88. PMID 12138206 DOI: 10.1128/Mcb.22.16.5975-5988.2002  0.364
2002 Pomeroy SL, Tamayo P, Gaasenbeek M, Sturla LM, Angelo M, McLaughlin ME, Kim JY, Goumnerova LC, Black PM, Lau C, Allen JC, Zagzag D, Olson JM, Curran T, Wetmore C, et al. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature. 415: 436-42. PMID 11807556 DOI: 10.1038/415436A  0.32
2001 Hormigo A, Friedlander DR, Brittis PA, Zagzag D, Grumet M. Reduced tumorigenicity of rat glioma cells in the brain when mediated by hygromycin phosphotransferase. Journal of Neurosurgery. 94: 596-604. PMID 11302658 DOI: 10.3171/Jns.2001.94.4.0596  0.422
2001 Neamtu L, Belmont M, Miller DC, Leroux P, Weinberg H, Zagzag D. Rheumatoid disease of the CNS with meningeal vasculitis presenting with a seizure. Neurology. 56: 814-5. PMID 11274328 DOI: 10.1212/Wnl.56.6.814-A  0.437
2000 Weiner HL, Huang H, Zagzag D, Boyce H, Lichtenbaum R, Ziff EB. Consistent and selective expression of the discoidin domain receptor-1 tyrosine kinase in human brain tumors. Neurosurgery. 47: 1400-9. PMID 11126911 DOI: 10.1097/00006123-200012000-00028  0.441
2000 Zagzag D, Miller DC, Knopp E, Farmer JP, Lee M, Biria S, Pellicer A, Epstein FJ, Allen JC. Primitive neuroectodermal tumors of the brainstem: investigation of seven cases. Pediatrics. 106: 1045-53. PMID 11061774 DOI: 10.1542/Peds.106.5.1045  0.55
2000 Zagzag D, Friedlander DR, Margolis B, Grumet M, Semenza GL, Zhong H, Simons JW, Holash J, Wiegand SJ, Yancopoulos GD. Molecular events implicated in brain tumor angiogenesis and invasion. Pediatric Neurosurgery. 33: 49-55. PMID 11025423 DOI: 10.1159/000028975  0.427
2000 Zagzag D, Amirnovin R, Greco MA, Yee H, Holash J, Wiegand SJ, Zabski S, Yancopoulos GD, Grumet M. Vascular apoptosis and involution in gliomas precede neovascularization: a novel concept for glioma growth and angiogenesis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 80: 837-49. PMID 10879735 DOI: 10.1038/Labinvest.3780088  0.448
2000 Zagzag D, Zhong H, Scalzitti JM, Laughner E, Simons JW, Semenza GL. Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression. Cancer. 88: 2606-18. PMID 10861440 DOI: 10.1002/1097-0142(20000601)88:11<2606::AID-CNCR25>3.0.CO;2-W  0.324
1999 Lyden D, Young AZ, Zagzag D, Yan W, Gerald W, O'Reilly R, Bader BL, Hynes RO, Zhuang Y, Manova K, Benezra R. Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts. Nature. 401: 670-7. PMID 10537105 DOI: 10.1038/44334  0.345
1999 Moreira AL, Friedlander DR, Shif B, Kaplan G, Zagzag D. Thalidomide and a thalidomide analogue inhibit endothelial cell proliferation in vitro. Journal of Neuro-Oncology. 43: 109-14. PMID 10533722 DOI: 10.1023/A:1006202700039  0.43
1999 Zagzag D, Hooper A, Friedlander DR, Chan W, Holash J, Wiegand SJ, Yancopoulos GD, Grumet M. In situ expression of angiopoietins in astrocytomas identifies angiopoietin-2 as an early marker of tumor angiogenesis. Experimental Neurology. 159: 391-400. PMID 10506510 DOI: 10.1006/Exnr.1999.7162  0.413
1999 Wang ZH, Zagzag D, Zeng B, Kolodny EH. In vivo and in vitro glioma cell killing induced by an adenovirus expressing both cytosine deaminase and thymidine kinase and its association with interferon-alpha. Journal of Neuropathology and Experimental Neurology. 58: 847-58. PMID 10446809 DOI: 10.1097/00005072-199908000-00007  0.39
1999 Holash J, Maisonpierre PC, Compton D, Boland P, Alexander CR, Zagzag D, Yancopoulos GD, Wiegand SJ. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science (New York, N.Y.). 284: 1994-8. PMID 10373119 DOI: 10.1126/Science.284.5422.1994  0.419
1999 Knopp EA, Cha S, Johnson G, Mazumdar A, Golfinos JG, Zagzag D, Miller DC, Kelly PJ, Kricheff II. Glial neoplasms: dynamic contrast-enhanced T2*-weighted MR imaging. Radiology. 211: 791-8. PMID 10352608 DOI: 10.1148/Radiology.211.3.R99Jn46791  0.477
1999 Zagzag D, Gultekin SH, Rosenblum MK. IMMUNOLOCALIZATION OF ANTI-HU AND RMD0–20 IN STROMAL CELLS OF HEMANGIOBLASTOMAS Journal of Neuropathology and Experimental Neurology. 58: 566. DOI: 10.1097/00005072-199905000-00240  0.305
1999 Amirnovin R, Holash J, Wiegand S, Yancopoulos G, Grument M, Zagzag D. ENDOTHELIAL CELL APOPTOSIS AND VASCULAR REGRESSION IN GLIOMAS PRECEDE NEOVASCULARIZATION Journal of Neuropathology and Experimental Neurology. 58: 537. DOI: 10.1097/00005072-199905000-00122  0.327
1998 Lossi L, Zagzag D, Greco MA, Merighi A. Apoptosis of undifferentiated progenitors and granule cell precursors in the postnatal human cerebellar cortex correlates with expression of BCL-2, ICE, and CPP32 proteins. The Journal of Comparative Neurology. 399: 359-72. PMID 9733083 DOI: 10.1002/(Sici)1096-9861(19980928)399:3<359::Aid-Cne5>3.0.Co;2-#  0.331
1998 Zonenshayn M, Sharma S, Hymes K, Knopp EA, Golfinos JG, Zagzag D. Mycosis fungoides metastasizing to the brain parenchyma: case report. Neurosurgery. 42: 933-7. PMID 9574661 DOI: 10.1097/00006123-199804000-00144  0.335
1998 Sharma S, Abbott RI, Zagzag D. Malignant intracerebral nerve sheath tumor: a case report and review of the literature. Cancer. 82: 545-52. PMID 9452273 DOI: 10.1002/(SICI)1097-0142(19980201)82:3<545::AID-CNCR17>3.0.CO;2-1  0.313
1998 Lamszus K, Schmidt NO, Jin L, Laterra J, Zagzag D, Way D, Witte M, Weinand M, Goldberg ID, Westphal M, Rosen EM. Scatter factor promotes motility of human glioma and neuromicrovascular endothelial cells. International Journal of Cancer. Journal International Du Cancer. 75: 19-28. PMID 9426685 DOI: 10.1002/(Sici)1097-0215(19980105)75:1<19::Aid-Ijc4>3.0.Co;2-4  0.413
1998 Berthelet F, Rosenblum M, Zagzag D. NECROSIS IS NOT A PROGNOSTIC FACTOR IN SUBEPENDYMAL GIANT CELL ASTROCYTOMA Journal of Neuropathology and Experimental Neurology. 57: 501. DOI: 10.1097/00005072-199805000-00147  0.322
1997 Jallo GI, Friedlander DR, Kelly PJ, Wisoff JH, Grumet M, Zagzag D. Tenascin-C expression in the cyst wall and fluid of human brain tumors correlates with angiogenesis. Neurosurgery. 41: 1052-9. PMID 9361058 DOI: 10.1097/00006123-199711000-00007  0.423
1997 Zeitouni AG, Zagzag D, Cohen NL. Meningioma of the internal auditory canal. The Annals of Otology, Rhinology, and Laryngology. 106: 657-61. PMID 9270429 DOI: 10.1177/000348949710600808  0.38
1997 Huang PP, Zagzag D, Benjamin V. Intracranial schwannoma presenting as a subfrontal tumor: case report. Neurosurgery. 40: 194-7. PMID 8971843 DOI: 10.1097/00006123-199701000-00043  0.379
1996 Jallo GI, Zagzag D, Epstein F. Intramedullary subependymoma of the spinal cord. Neurosurgery. 38: 251-7. PMID 8869051 DOI: 10.1097/00006123-199602000-00004  0.349
1996 Rezai AR, Woo HH, Lee M, Cohen H, Zagzag D, Epstein FJ. Disseminated ependymomas of the central nervous system. Journal of Neurosurgery. 85: 618-24. PMID 8814165 DOI: 10.3171/Jns.1996.85.4.0618  0.408
1996 Friedlander DR, Zagzag D, Shiff B, Cohen H, Allen JC, Kelly PJ, Grumet M. Migration of brain tumor cells on extracellular matrix proteins in vitro correlates with tumor type and grade and involves alphaV and beta1 integrins. Cancer Research. 56: 1939-47. PMID 8620517  0.324
1996 Zagzag D, Friedlander DR, Dosik J, Chikramane S, Chan W, Greco MA, Allen JC, Dorovini-Zis K, Grumet M. Tenascin-C expression by angiogenic vessels in human astrocytomas and by human brain endothelial cells in vitro. Cancer Research. 56: 182-9. PMID 8548761  0.312
1995 Zagzag D, Friedlander DR, Miller DC, Dosik J, Cangiarella J, Kostianovsky M, Cohen H, Grumet M, Greco MA. Tenascin expression in astrocytomas correlates with angiogenesis. Cancer Research. 55: 907-14. PMID 7531617  0.525
1995 Zagzag D, Friedlander DR, Dosik J, Chan W, Chikramane S, Dorovini-Zis K, Grumet M. IN SITU EXPRESSION OF TENASCIN IN ASTROCYTOMAS AND BY HUMAN BRAIN ENDOTHELIAL CELLS IN VITRO Journal of Neuropathology and Experimental Neurology. 54: 438. DOI: 10.1097/00005072-199505000-00125  0.348
1994 Kleinman GM, Zagzag D, Miller DC. Diagnostic use of immunohistochemistry in neuropathology. Neurosurgery Clinics of North America. 5: 97-126. PMID 8124096 DOI: 10.1016/S1042-3680(18)30545-X  0.489
1994 Weiner HL, Wisoff JH, Rosenberg ME, Kupersmith MJ, Cohen H, Zagzag D, Shiminski-Maher T, Flamm ES, Epstein FJ, Miller DC. Craniopharyngiomas: a clinicopathological analysis of factors predictive of recurrence and functional outcome. Neurosurgery. 35: 1001-10; discussion . PMID 7885544 DOI: 10.1227/00006123-199412000-00001  0.555
1993 Weiner HL, Zagzag D, Babu R, Weinreb HJ, Ransohoff J. Schwannoma of the fourth ventricle presenting with hemifacial spasm. A report of two cases. Journal of Neuro-Oncology. 15: 37-43. PMID 8455061 DOI: 10.1007/Bf01050261  0.34
1993 Zagzag D, Miller DC, Kleinman GM, Abati A, Donnenfeld H, Budzilovich GN. Demyelinating disease versus tumor in surgical neuropathology. Clues to a correct pathological diagnosis. The American Journal of Surgical Pathology. 17: 537-45. PMID 8333553 DOI: 10.1097/00000478-199306000-00001  0.513
1992 Zagzag D, Miller DC, Cangiarella J, Allen JC, Greco MA. Brainstem glioma after radiation therapy for acute myeloblastic leukemia in a child with Down syndrome. Possible pathogenetic mechanisms. Cancer. 70: 1188-93. PMID 1387583  0.423
1990 Brem S, Tsanaclis AM, Zagzag D. Anticopper treatment inhibits pseudopodial protrusion and the invasive spread of 9L gliosarcoma cells in the rat brain. Neurosurgery. 26: 391-6. PMID 2320207 DOI: 10.1097/00006123-199003000-00003  0.393
1990 Zagzag D, Miller DC, Sato Y, Rifkin DB, Burstein DE. Immunohistochemical localization of basic fibroblast growth factor in astrocytomas. Cancer Research. 50: 7393-8. PMID 2171762  0.528
1989 Brien SE, Zagzag D, Brem S. Rapid in situ cellular kinetics of intracerebral tumor angiogenesis using a monoclonal antibody to bromodeoxyuridine. Neurosurgery. 25: 715-9. PMID 2479879 DOI: 10.1097/00006123-198911000-00005  0.443
1989 Zagzag D, Goldenberg M, Brem S. Angiogenesis and blood-brain barrier breakdown modulate CT contrast enhancement: an experimental study in a rabbit brain-tumor model. Ajr. American Journal of Roentgenology. 153: 141-6. PMID 2472056 DOI: 10.2214/Ajr.153.1.141  0.403
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