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Edgar F. da Cruz e Silva, PhD - Publications

Affiliations: 
Cell Biology University of Aveiro, Aveiro, Aveiro, Portugal 
Area:
http://www.biomedexperts.com/Profile.bme/281667/Edgar_F_da_Cruz_e_Silva
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63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Rebelo S, da Cruz E Silva EF, da Cruz E Silva OA. Genetic mutations strengthen functional association of LAP1 with DYT1 dystonia and muscular dystrophy. Mutation Research. Reviews in Mutation Research. 766: 42-7. PMID 26596547 DOI: 10.1016/J.Mrrev.2015.07.004  0.804
2015 Martins F, Rebelo S, Santos M, Cotrim CZ, da Cruz E Silva EF, da Cruz E Silva OA. BRI2 and BRI3 are functionally distinct phosphoproteins. Cellular Signalling. PMID 26515131 DOI: 10.1016/J.Cellsig.2015.10.012  0.844
2015 Rebelo S, Santos M, Martins F, da Cruz E Silva EF, da Cruz E Silva OA. Protein phosphatase 1 is a key player in nuclear events. Cellular Signalling. PMID 26275498 DOI: 10.1016/J.Cellsig.2015.08.007  0.838
2015 Silva JV, Yoon S, Domingues S, Guimarães S, Goltsev AV, da Cruz E Silva EF, Mendes JF, da Cruz E Silva OA, Fardilha M. Amyloid precursor protein interaction network in human testis: sentinel proteins for male reproduction. Bmc Bioinformatics. 16: 12. PMID 25591988 DOI: 10.1186/S12859-014-0432-9  0.833
2015 Silva JV, Korrodi-Gregório L, Luers G, Cardoso MJ, Patrício A, Maia N, da Cruz E Silva EF, Fardilha M. Characterisation of several ankyrin repeat protein variant 2, a phosphoprotein phosphatase 1-interacting protein, in testis and spermatozoa. Reproduction, Fertility, and Development. PMID 25562328 DOI: 10.1071/Rd14303  0.675
2015 Santos M, Costa P, Martins F, da Cruz e Silva EF, da Cruz e Silva OA, Rebelo S. LAP1 is a crucial protein for the maintenance of the nuclear envelope structure and cell cycle progression. Molecular and Cellular Biochemistry. 399: 143-53. PMID 25323962 DOI: 10.1007/S11010-014-2241-X  0.803
2014 Santos M, Domingues SC, Costa P, Muller T, Galozzi S, Marcus K, da Cruz e Silva EF, da Cruz e Silva OA, Rebelo S. Identification of a novel human LAP1 isoform that is regulated by protein phosphorylation. Plos One. 9: e113732. PMID 25461922 DOI: 10.1371/Journal.Pone.0113732  0.834
2014 Domingues SC, Konietzko U, Henriques AG, Rebelo S, Fardilha M, Nishitani H, Nitsch RM, da Cruz E Silva EF, da Cruz E Silva OA. RanBP9 modulates AICD localization and transcriptional activity via direct interaction with Tip60. Journal of Alzheimer's Disease : Jad. 42: 1415-33. PMID 25024339 DOI: 10.3233/Jad-132495  0.814
2014 Henriques AG, Oliveira JM, Gomes B, Ruivo R, da Cruz e Silva EF, da Cruz e Silva OA. Complexing Aβ prevents the cellular anomalies induced by the Peptide alone. Journal of Molecular Neuroscience : Mn. 53: 661-8. PMID 24599756 DOI: 10.1007/S12031-014-0233-7  0.812
2013 Korrodi-Gregório L, Margarida Lopes A, Esteves SL, Afonso S, Lemos de Matos A, Lissovsky AA, da Cruz e Silva OA, da Cruz e Silva EF, Esteves PJ, Fardilha M. An intriguing shift occurs in the novel protein phosphatase 1 binding partner, TCTEX1D4: evidence of positive selection in a pika model. Plos One. 8: e77236. PMID 24130861 DOI: 10.1371/Journal.Pone.0077236  0.799
2013 Santos M, Rebelo S, Van Kleeff PJ, Kim CE, Dauer WT, Fardilha M, da Cruz E Silva OA, da Cruz E Silva EF. The nuclear envelope protein, LAP1B, is a novel protein phosphatase 1 substrate. Plos One. 8: e76788. PMID 24116158 DOI: 10.1371/Journal.Pone.0076788  0.826
2013 Fardilha M, Ferreira M, Pelech S, Vieira S, Rebelo S, Korrodi-Gregorio L, Sousa M, Barros A, Silva V, da Cruz e Silva OA, da Cruz e Silva EF. "Omics" of human sperm: profiling protein phosphatases. Omics : a Journal of Integrative Biology. 17: 460-72. PMID 23895272 DOI: 10.1089/Omi.2012.0119  0.815
2013 Korrodi-Gregório L, Vieira SI, Esteves SL, Silva JV, Freitas MJ, Brauns AK, Luers G, Abrantes J, Esteves PJ, da Cruz E Silva OA, Fardilha M, da Cruz E Silva EF. TCTEX1D4, a novel protein phosphatase 1 interactor: connecting the phosphatase to the microtubule network. Biology Open. 2: 453-65. PMID 23789093 DOI: 10.1242/Bio.20131065  0.835
2013 Rebelo S, Domingues SC, Santos M, Fardilha M, Esteves SL, Vieira SI, Vintém AP, Wu W, da Cruz E Silva EF, da Cruz E Silva OA. Identification of a novel complex AβPP:Fe65:PP1 that regulates AβPP Thr668 phosphorylation levels. Journal of Alzheimer's Disease : Jad. 35: 761-75. PMID 23531501 DOI: 10.3233/Jad-130095  0.836
2013 Korrodi-Gregório L, Ferreira M, Vintém AP, Wu W, Muller T, Marcus K, Vijayaraghavan S, Brautigan DL, da Cruz E Silva OA, Fardilha M, da Cruz E Silva EF. Identification and characterization of two distinct PPP1R2 isoforms in human spermatozoa. Bmc Cell Biology. 14: 15. PMID 23506001 DOI: 10.1186/1471-2121-14-15  0.823
2013 Esteves SL, Korrodi-Gregório L, Cotrim CZ, van Kleeff PJ, Domingues SC, da Cruz e Silva OA, Fardilha M, da Cruz e Silva EF. Protein phosphatase 1γ isoforms linked interactions in the brain. Journal of Molecular Neuroscience : Mn. 50: 179-97. PMID 23080069 DOI: 10.1007/S12031-012-9902-6  0.849
2012 Esteves SL, Domingues SC, da Cruz e Silva OA, Fardilha M, da Cruz e Silva EF. Protein phosphatase 1α interacting proteins in the human brain. Omics : a Journal of Integrative Biology. 16: 3-17. PMID 22321011 DOI: 10.1089/Omi.2011.0041  0.838
2011 Domingues SC, Henriques AG, Fardilha M, da Cruz E Silva EF, da Cruz E Silva OA. Identification and characterization of a neuronal enriched novel transcript encoding the previously described p60Fe65 isoform. Journal of Neurochemistry. 119: 1086-98. PMID 21824145 DOI: 10.1111/J.1471-4159.2011.07420.X  0.81
2011 Casaca A, Fardilha M, da Cruz e Silva E, Cunha C. The heterogeneous ribonuclear protein C interacts with the hepatitis delta virus small antigen. Virology Journal. 8: 358. PMID 21774814 DOI: 10.1186/1743-422X-8-358  0.581
2011 Casaca A, Fardilha M, da Cruz E Silva E, Cunha C. In Vivo Interaction of the Hepatitis Delta Virus Small Antigen with the ELAV-Like Protein HuR. The Open Virology Journal. 5: 12-21. PMID 21660185 DOI: 10.2174/1874357901105010012  0.614
2011 Fardilha M, Esteves SL, Korrodi-Gregório L, Vintém AP, Domingues SC, Rebelo S, Morrice N, Cohen PT, da Cruz e Silva OA, da Cruz e Silva EF. Identification of the human testis protein phosphatase 1 interactome. Biochemical Pharmacology. 82: 1403-15. PMID 21382349 DOI: 10.1016/J.Bcp.2011.02.018  0.832
2011 Fardilha M, Esteves SL, Korrodi-Gregório L, Pelech S, da Cruz E Silva OA, da Cruz E Silva E. Protein phosphatase 1 complexes modulate sperm motility and present novel targets for male infertility. Molecular Human Reproduction. 17: 466-77. PMID 21257602 DOI: 10.1093/Molehr/Gar004  0.842
2010 Fardilha M, Schrader M, da Cruz E Silva OA, da Cruz E Silva EF. Understanding fatty acid metabolism through an active learning approach. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. 38: 65-9. PMID 21567798 DOI: 10.1002/Bmb.20330  0.747
2010 da Cruz e Silva OA, Henriques AG, Domingues SC, da Cruz e Silva EF. Wnt signalling is a relevant pathway contributing to amyloid beta- peptide-mediated neuropathology in Alzheimer's disease. Cns & Neurological Disorders Drug Targets. 9: 720-6. PMID 20942790 DOI: 10.2174/187152710793237458  0.833
2010 Vieira SI, Rebelo S, Esselmann H, Wiltfang J, Lah J, Lane R, Small SA, Gandy S, da Cruz E Silva EF, da Cruz E Silva OA. Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated. Molecular Neurodegeneration. 5: 40. PMID 20937087 DOI: 10.1186/1750-1326-5-40  0.842
2010 Pina S, Vieira SI, Rego P, Torres PM, da Cruz e Silva OA, da Cruz e Silva EF, Ferreira JM. Biological responses of brushite-forming Zn- and ZnSr- substituted beta-tricalcium phosphate bone cements. European Cells & Materials. 20: 162-77. PMID 20821372  0.744
2010 Pina S, Vieira SI, Torres PM, Goetz-Neunhoeffer F, Neubauer J, da Cruz E Silva OA, da Cruz E Silva EF, Ferreira JM. In vitro performance assessment of new brushite-forming Zn- and ZnSr-substituted beta-TCP bone cements. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 94: 414-20. PMID 20574977 DOI: 10.1002/jbm.b.31669  0.736
2010 Amorim MA, Guerra-Araiza C, Pernía O, da Cruz e Silva EF, Garcia-Segura LM. Progesterone regulates the phosphorylation of protein phosphatases in the brain. Journal of Neuroscience Research. 88: 2826-32. PMID 20568292 DOI: 10.1002/jnr.22442  0.55
2010 Henriques AG, Vieira SI, da Cruz E Silva EF, da Cruz E Silva OA. Abeta promotes Alzheimer's disease-like cytoskeleton abnormalities with consequences to APP processing in neurons. Journal of Neurochemistry. 113: 761-71. PMID 20345756 DOI: 10.1111/J.1471-4159.2010.06643.X  0.816
2009 Vieira SI, Rebelo S, Domingues SC, da Cruz e Silva EF, da Cruz e Silva OA. S655 phosphorylation enhances APP secretory traffic. Molecular and Cellular Biochemistry. 328: 145-54. PMID 19381782 DOI: 10.1007/S11010-009-0084-7  0.841
2009 Henriques AG, Vieira SI, da Cruz e Silva EF, da Cruz e Silva OA. Alphabeta hinders nuclear targeting of AICD and Fe65 in primary neuronal cultures. Journal of Molecular Neuroscience : Mn. 39: 248-55. PMID 19340611 DOI: 10.1007/S12031-009-9192-9  0.827
2009 Henriques AG, Vieira SI, Crespo-López ME, Guiomar de Oliveira MA, da Cruz e Silva EF, da Cruz e Silva OA. Intracellular sAPP retention in response to Abeta is mapped to cytoskeleton-associated structures. Journal of Neuroscience Research. 87: 1449-61. PMID 19105196 DOI: 10.1002/Jnr.21959  0.817
2009 Vintém AP, Henriques AG, da Cruz E Silva OA, da Cruz E Silva EF. PP1 inhibition by Abeta peptide as a potential pathological mechanism in Alzheimer's disease. Neurotoxicology and Teratology. 31: 85-8. PMID 19028567 DOI: 10.1016/J.Ntt.2008.11.001  0.827
2009 da Cruz e Silva OA, Rebelo S, Vieira SI, Gandy S, da Cruz e Silva EF, Greengard P. Enhanced generation of Alzheimer's amyloid-beta following chronic exposure to phorbol ester correlates with differential effects on alpha and epsilon isozymes of protein kinase C. Journal of Neurochemistry. 108: 319-30. PMID 19012746 DOI: 10.1111/J.1471-4159.2008.05770.X  0.847
2008 Rebelo S, Vieira SI, da Cruz E Silva EF, da Cruz E Silva OA. Monitoring "De Novo"APP synthesis by taking advantage of the reversible effect of cycloheximide. American Journal of Alzheimer's Disease and Other Dementias. 23: 602-8. PMID 19106277 DOI: 10.1177/1533317508323572  0.847
2008 Sousa C, Vintém AP, Fardilha M, Da Cruz E Silva O, Da Cruz E Silva E. Subcellular localization of a novel alternative splicing of IIIG9 and colocalization with PPP1gamma isoforms Microscopy and Microanalysis. 14: 141-143. DOI: 10.1017/S143192760808968X  0.771
2007 Rebelo S, Vieira SI, Esselmann H, Wiltfang J, da Cruz e Silva EF, da Cruz e Silva OA. Tyr687 dependent APP endocytosis and Abeta production. Journal of Molecular Neuroscience : Mn. 32: 1-8. PMID 17873282 DOI: 10.1007/S12031-007-0001-Z  0.837
2007 Wu W, Baxter JE, Wattam SL, Hayward DG, Fardilha M, Knebel A, Ford EM, da Cruz e Silva EF, Fry AM. Alternative splicing controls nuclear translocation of the cell cycle-regulated Nek2 kinase. The Journal of Biological Chemistry. 282: 26431-40. PMID 17626005 DOI: 10.1074/Jbc.M704969200  0.733
2007 Rebelo S, Vieira SI, Esselmann H, Wiltfang J, da Cruz e Silva EF, da Cruz e Silva OA. Tyrosine 687 phosphorylated Alzheimer's amyloid precursor protein is retained intracellularly and exhibits a decreased turnover rate. Neuro-Degenerative Diseases. 4: 78-87. PMID 17596701 DOI: 10.1159/000101831  0.837
2007 Fardilha M, Vieira SI, Barros A, Sousa M, Da Cruz e Silva OA, Da Cruz e Silva EF. Differential distribution of Alzheimer's amyloid precursor protein family variants in human sperm. Annals of the New York Academy of Sciences. 1096: 196-206. PMID 17405931 DOI: 10.1196/Annals.1397.086  0.838
2007 Domingues SC, Henriques AG, Wu W, Da Cruz e Silva EF, Da Cruz e Silva OA. Altered subcellular distribution of the Alzheimer's amyloid precursor protein under stress conditions. Annals of the New York Academy of Sciences. 1096: 184-95. PMID 17405930 DOI: 10.1196/Annals.1397.085  0.833
2007 Henriques AG, Vieira SI, Rebelo S, Domingues SC, da Cruz e Silva EF, da Cruz e Silva OA. Isoform specific amyloid-beta protein precursor metabolism. Journal of Alzheimer's Disease : Jad. 11: 85-95. PMID 17361038 DOI: 10.3233/Jad-2007-11112  0.831
2007 Browne GJ, Fardilha M, Oxenham SK, Wu W, Helps NR, da Cruz E Silva OA, Cohen PT, da Cruz E Silva EF. SARP, a new alternatively spliced protein phosphatase 1 and DNA interacting protein. The Biochemical Journal. 402: 187-96. PMID 17123353 DOI: 10.1042/Bj20060600  0.83
2005 Henriques AG, Domingues SC, Fardilha M, da Cruz e Silva EF, da Cruz e Silva OA. Sodium azide and 2-deoxy-D-glucose-induced cellular stress affects phosphorylation-dependent AbetaPP processing. Journal of Alzheimer's Disease : Jad. 7: 201-12; discussion 2. PMID 16006663 DOI: 10.3233/Jad-2005-7302  0.813
2004 da Cruz E Silva OA, Vieira SI, Rebelo S, da Cruz e Silva EF. A model system to study intracellular trafficking and processing of the Alzheimer's amyloid precursor protein. Neuro-Degenerative Diseases. 1: 196-204. PMID 16908990 DOI: 10.1159/000080986  0.85
2004 Fardilha M, Wu W, Sá R, Fidalgo S, Sousa C, Mota C, da Cruz e Silva OA, da Cruz e Silva EF. Alternatively spliced protein variants as potential therapeutic targets for male infertility and contraception. Annals of the New York Academy of Sciences. 1030: 468-78. PMID 15659832 DOI: 10.1196/Annals.1329.059  0.813
2004 da Cruz e Silva OA, Fardilha M, Henriques AG, Rebelo S, Vieira S, da Cruz e Silva EF. Signal transduction therapeutics: relevance for Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 23: 123-42. PMID 15126698 DOI: 10.1385/Jmn:23:1-2:123  0.843
2004 Amador FC, Henriques AG, da Cruz E Silva OA, da Cruz E Silva EF. Monitoring protein phosphatase 1 isoform levels as a marker for cellular stress. Neurotoxicology and Teratology. 26: 387-95. PMID 15113600 DOI: 10.1016/J.Ntt.2003.12.007  0.835
2004 Rebelo S, Henriques AG, da Cruz e Silva EF, da Cruz e Silva OA. Effect of cell density on intracellular levels of the Alzheimer's amyloid precursor protein. Journal of Neuroscience Research. 76: 406-14. PMID 15079870 DOI: 10.1002/Jnr.20091  0.819
2003 Watanabe T, da Cruz e Silva EF, Huang HB, Starkova N, Kwon YG, Horiuchi A, Greengard P, Nairn AC. Preparation and characterization of recombinant protein phosphatase 1. Methods in Enzymology. 366: 321-38. PMID 14674258 DOI: 10.1016/S0076-6879(03)66024-6  0.57
2003 da Cruz e Silva EF, da Cruz e Silva OA. Protein phosphorylation and APP metabolism. Neurochemical Research. 28: 1553-61. PMID 14570401 DOI: 10.1023/A:1025630627319  0.848
2003 Watanabe T, Da Cruz E Silva EF, Huang HB, Starkova N, Kwon YG, Horiuchi A, Greengard P, Nairn AC. [24] Preparation and Characterization of Recombinant Protein Phosphatase 1 Methods in Enzymology. 366: 321-338.  0.538
1996 Smith GD, Wolf DP, Trautman KC, da Cruz e Silva EF, Greengard P, Vijayaraghavan S. Primate sperm contain protein phosphatase 1, a biochemical mediator of motility. Biology of Reproduction. 54: 719-27. PMID 8835396 DOI: 10.1095/Biolreprod54.3.719  0.46
1996 Vijayaraghavan S, Stephens DT, Trautman K, Smith GD, Khatra B, da Cruz e Silva EF, Greengard P. Sperm motility development in the epididymis is associated with decreased glycogen synthase kinase-3 and protein phosphatase 1 activity. Biology of Reproduction. 54: 709-18. PMID 8835395 DOI: 10.1095/Biolreprod54.3.709  0.481
1995 da Cruz e Silva EF, da Cruz e Silva OA, Zaia CT, Greengard P. Inhibition of protein phosphatase 1 stimulates secretion of Alzheimer amyloid precursor protein. Molecular Medicine (Cambridge, Mass.). 1: 535-41. PMID 8529119  0.83
1995 Desdouits F, Cheetham JJ, Huang HB, Kwon YG, da Cruz e Silva EF, Denefle P, Ehrlich ME, Nairn AC, Greengard P, Girault JA. Mechanism of inhibition of protein phosphatase 1 by DARPP-32: studies with recombinant DARPP-32 and synthetic peptides. Biochemical and Biophysical Research Communications. 206: 652-8. PMID 7826384 DOI: 10.1006/bbrc.1995.1092  0.785
1995 da Cruz e Silva EF, Fox CA, Ouimet CC, Gustafson E, Watson SJ, Greengard P. Differential expression of protein phosphatase 1 isoforms in mammalian brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 3375-89. PMID 7751917  0.65
1995 Ouimet CC, da Cruz e Silva EF, Greengard P. The alpha and gamma 1 isoforms of protein phosphatase 1 are highly and specifically concentrated in dendritic spines. Proceedings of the National Academy of Sciences of the United States of America. 92: 3396-400. PMID 7724573 DOI: 10.1073/PNAS.92.8.3396  0.678
1995 Li D, Aperia A, Celsi G, da Cruz e Silva EF, Greengard P, Meister B. Protein phosphatase-1 in the kidney: evidence for a role in the regulation of medullary Na(+)-K(+)-ATPase. The American Journal of Physiology. 269: F673-80. PMID 7503233 DOI: 10.1152/AJPRENAL.1995.269.5.F673  0.419
1994 Dohadwala M, da Cruz e Silva EF, Hall FL, Williams RT, Carbonaro-Hall DA, Nairn AC, Greengard P, Berndt N. Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases. Proceedings of the National Academy of Sciences of the United States of America. 91: 6408-12. PMID 8022797 DOI: 10.1073/Pnas.91.14.6408  0.656
1989 Chen LR, Yuan CJ, Somasekhar G, Wejksnora P, Peterson JE, Myers AM, Graves L, Cohen PT, da Cruz e Silva EF, Graves DJ. Expression and characterization of the tau subunit of phosphorylase kinase. Biochemical and Biophysical Research Communications. 161: 746-53. PMID 2735920 DOI: 10.1016/0006-291X(89)92663-6  0.336
1988 da Cruz e Silva OB, da Cruz e Silva EF, Cohen PT. Identification of a novel protein phosphatase catalytic subunit by cDNA cloning. Febs Letters. 242: 106-10. PMID 2849555 DOI: 10.1016/0014-5793(88)80995-5  0.336
1987 Berndt N, Campbell DG, Caudwell FB, Cohen P, da Cruz e Silva EF, da Cruz e Silva OB, Cohen PT. Isolation and sequence analysis of a cDNA clone encoding a type-1 protein phosphatase catalytic subunit: homology with protein phosphatase 2A. Febs Letters. 223: 340-6. PMID 2822491 DOI: 10.1016/0014-5793(87)80316-2  0.706
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