Praveen Sethupathy, Ph.D. - Publications

Affiliations: 
2008 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Bioinformatics Biology, Genetics, Computer Science

65/152 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Taylor HJ, Hung YH, Narisu N, Erdos MR, Kanke M, Yan T, Grenko CM, Swift AJ, Bonnycastle LL, Sethupathy P, Collins FS, Taylor DL. Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis. Proceedings of the National Academy of Sciences of the United States of America. 120: e2206797120. PMID 36757889 DOI: 10.1073/pnas.2206797120  0.348
2022 Francisco AB, Kanke M, Massa AP, Dinh TA, Sritharan R, Vakili K, Bardeesy N, Sethupathy P. Multiomic analysis of microRNA-mediated regulation reveals a proliferative axis involving miR-10b in fibrolamellar carcinoma. Jci Insight. 7. PMID 35482409 DOI: 10.1172/jci.insight.154743  0.323
2021 Que E, James KL, Coffey AR, Smallwood TL, Albright J, Huda MN, Pomp D, Sethupathy P, Bennett BJ. Genetic architecture modulates diet-induced hepatic mRNA and miRNA expression profiles in Diversity Outbred mice. Genetics. 218. PMID 34849860 DOI: 10.1093/genetics/iyab068  0.307
2021 O'Connor S, Murphy EA, Szwed SK, Kanke M, Marchildon F, Sethupathy P, Darnell RB, Cohen P. AGO HITS-CLIP reveals distinct miRNA regulation of white and brown adipose tissue identity. Genes & Development. PMID 33832988 DOI: 10.1101/gad.345447.120  0.317
2020 Hsiao K, Noble C, Pitman W, Yadav N, Kumar S, Keele GR, Terceros A, Kanke M, Conniff T, Cheleuitte-Nieves C, Tolwani R, Sethupathy P, Rajasethupathy P. A Thalamic Orphan Receptor Drives Variability in Short-Term Memory. Cell. PMID 32997977 DOI: 10.1016/j.cell.2020.09.011  0.493
2020 Que E, James KL, Coffey AR, Smallwood TL, Albright J, Huda MN, Pomp D, Sethupathy P, Bennett BJ. Genetic Architecture Modulates Diet Induced Hepatic mRNA and miRNA Expression Profiles in Diversity Outbred Mice. Genetics. PMID 32763908 DOI: 10.1534/Genetics.120.303481  0.414
2020 Que E, James KL, Coffey AR, Smallwood TL, Albright J, Huda MN, Pomp D, Sethupathy P, Bennett BJ. Genetic Architecture Modulates Diet Induced Hepatic mRNA and miRNA Expression Profiles in Diversity Outbred Mice. Genetics. PMID 32763908 DOI: 10.1534/genetics.120.303481  0.309
2020 Toyonaga T, Steinbach EC, Keith BP, Barrow JB, Schaner MR, Wolber EA, Beasley C, Huling J, Wang Y, Allbritton NL, Chaumont N, Sadiq TS, Koruda MJ, Jain A, Long MD, ... ... Sethupathy P, et al. Decreased Colonic Activin Receptor-Like Kinase 1 Disrupts Epithelial Barrier Integrity in Patients with Crohn's disease. Cellular and Molecular Gastroenterology and Hepatology. PMID 32561494 DOI: 10.1016/J.Jcmgh.2020.06.005  0.315
2020 Dinh TA, Sritharan R, Smith FD, Francisco AB, Ma RK, Bunaciu RP, Kanke M, Danko CG, Massa AP, Scott JD, Sethupathy P. Hotspots of Aberrant Enhancer Activity in Fibrolamellar Carcinoma Reveal Candidate Oncogenic Pathways and Therapeutic Vulnerabilities. Cell Reports. 31: 107509. PMID 32294439 DOI: 10.1016/J.Celrep.2020.03.073  0.307
2019 Singh AP, Hung YH, Shanahan MT, Kanke M, Bonfini A, Dame MK, Biraud M, Peck BCE, Oyesola OO, Freund JM, Cubitt RL, Curry EG, Gonzalez LM, Bewick GA, Tait-Wojno ED, ... ... Sethupathy P, et al. Enteroendocrine progenitor cell enriched miR-7 regulates intestinal epithelial proliferation in an Xiap-dependent manner. Cellular and Molecular Gastroenterology and Hepatology. PMID 31756561 DOI: 10.1016/J.Jcmgh.2019.11.001  0.404
2019 Beck R, Chandi M, Kanke M, Stýblo M, Sethupathy P. Arsenic is more potent than cadmium or manganese in disrupting the INS-1 beta cell microRNA landscape. Archives of Toxicology. PMID 31555879 DOI: 10.1007/S00204-019-02574-8  0.381
2019 Hung YH, Kanke M, Kurtz CL, Cubitt R, Bunaciu RP, Miao J, Zhou L, Graham JL, Hussain M, Havel PJ, Biddinger SB, White PJ, Sethupathy P. Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice. Physiological Genomics. PMID 31251698 DOI: 10.1152/Physiolgenomics.00037.2019  0.405
2019 Dinh TA, Jewell ML, Kanke M, Francisco A, Sritharan R, Turnham RE, Lee S, Kastenhuber ER, Wauthier E, Guy CD, Yeung RS, Lowe SW, Reid LM, Scott JD, Diehl AM, ... Sethupathy P, et al. MicroRNA-375 suppresses the growth and invasion of fibrolamellar carcinoma. Cellular and Molecular Gastroenterology and Hepatology. PMID 30763770 DOI: 10.1016/J.Jcmgh.2019.01.008  0.378
2019 Lawlor N, Márquez EJ, Orchard P, Narisu N, Shamim MS, Thibodeau A, Varshney A, Kursawe R, Erdos MR, Kanke M, Gu H, Pak E, Dutra A, Russell S, Li X, ... ... Sethupathy P, et al. Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and Function. Cell Reports. 26: 788-801.e6. PMID 30650367 DOI: 10.1016/J.Celrep.2018.12.083  0.342
2019 Coffey AR, Kanke M, Smallwood TL, Albright J, Pitman W, Gharaibeh RZ, Hua K, Gertz E, Biddinger SB, Temel RE, Pomp D, Sethupathy P, Bennett BJ. microRNA-146a association with the cardiometabolic disease risk factor TMAO. Physiological Genomics. PMID 30633643 DOI: 10.1152/Physiolgenomics.00079.2018  0.33
2019 SETHUPATHY P. 1708-P: Enteroendocrine Lineage Enriched microRNAs Regulate Intestinal Progenitor Cell Dynamics Diabetes. 68: 1708-P. DOI: 10.2337/Db19-1708-P  0.312
2018 Beck RF, Bommarito P, Douillet C, Kanke M, Del Razo LM, García-Vargas G, Fry RC, Sethupathy P, Styblo M. Circulating miRNAs associated with arsenic exposure. Environmental Science & Technology. PMID 30457847 DOI: 10.1021/Acs.Est.8B06457  0.402
2018 Allen RM, Zhao S, Ramirez Solano MA, Zhu W, Michell DL, Wang Y, Shyr Y, Sethupathy P, Linton MF, Graf GA, Sheng Q, Vickers KC. Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins. Journal of Extracellular Vesicles. 7: 1506198. PMID 30128086 DOI: 10.1080/20013078.2018.1506198  0.364
2018 Bensen JT, Graff M, Young KL, Sethupathy P, Parker J, Pecot CV, Currin K, Haddad SA, Ruiz-Narváez EA, Haiman CA, Hong CC, Sucheston-Campbell LE, Zhu Q, Liu S, Yao S, et al. A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women. Breast Cancer Research : Bcr. 20: 45. PMID 29871690 DOI: 10.1186/S13058-018-0964-4  0.389
2018 Hung YH, Sethupathy P. MicroRNAs in the Mammalian Gut Endocrine Lineage. Endocrinology. 159: 866-868. PMID 29579172 DOI: 10.1210/En.2017-03117  0.417
2017 Yan X, Wang Z, Westberg-Rasmussen S, Tarbier M, Rathjen T, Tattikota SG, Peck BCE, Kanke M, Oxvig C, Frystyk J, Starup-Linde J, Sethupathy P, Friedländer MR, Gregersen S, Poy MN. Differential impact of glucose administered intravenously and orally on circulating miR-375 levels in human subjects. The Journal of Clinical Endocrinology and Metabolism. PMID 28973164 DOI: 10.1210/Jc.2017-01365  0.394
2017 Coffey AR, Smallwood TL, Albright J, Hua K, Kanke M, Pomp D, Bennett BJ, Sethupathy P. Systems genetics identifies a co-regulated module of liver microRNAs associated with plasma LDL cholesterol in murine diet-induced dyslipidemia. Physiological Genomics. physiolgenomics.0005. PMID 28916633 DOI: 10.1152/Physiolgenomics.00050.2017  0.436
2017 Gomez JC, Dang H, Kanke M, Hagan RS, Mock JR, Kelada SNP, Sethupathy P, Doerschuk CM. Predicted effects of observed changes in the mRNA and microRNA transcriptome of lung neutrophils during S. pneumoniae pneumonia in mice. Scientific Reports. 7: 11258. PMID 28900269 DOI: 10.1038/S41598-017-11638-7  0.334
2017 Smith KN, Starmer J, Miller SC, Sethupathy P, Magnuson T. Long Noncoding RNA Moderates MicroRNA Activity to Maintain Self-Renewal in Embryonic Stem Cells. Stem Cell Reports. PMID 28579393 DOI: 10.1016/J.Stemcr.2017.05.005  0.379
2017 Dinh TA, Vitucci EC, Wauthier E, Graham RP, Pitman WA, Oikawa T, Chen M, Silva GO, Greene KG, Torbenson MS, Reid LM, Sethupathy P. Comprehensive analysis of The Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma. Scientific Reports. 7: 44653. PMID 28304380 DOI: 10.1038/Srep44653  0.305
2017 Yamane D, Selitsky SR, Shimakami T, Li Y, Zhou M, Honda M, Sethupathy P, Lemon SM. Differential hepatitis C virus RNA target site selection and host factor activities of naturally occurring miR-122 3' variants. Nucleic Acids Research. PMID 28082397 DOI: 10.1093/Nar/Gkw1332  0.395
2017 Peck BC, Mah AT, Pitman WA, Ding S, Lund PK, Sethupathy P. Functional Transcriptomics in Diverse Intestinal Epithelial Cell Types Reveals Robust microRNA Sensitivity in Intestinal Stem Cells to Microbial Status. The Journal of Biological Chemistry. PMID 28053090 DOI: 10.1074/Jbc.M116.770099  0.432
2016 Kanke M, Baran-Gale J, Villanueva J, Sethupathy P. miRquant 2.0: an Expanded Tool for Accurate Annotation and Quantification of MicroRNAs and their isomiRs from Small RNA-Sequencing Data. Journal of Integrative Bioinformatics. 13: 307. PMID 28187421 DOI: 10.2390/Biecoll-Jib-2016-307  0.352
2016 Baran-Gale J, Purvis JE, Sethupathy P. An integrative transcriptomics approach identifies miR-503 as a candidate master regulator of the estrogen response in MCF-7 breast cancer cells. Rna (New York, N.Y.). PMID 27539783 DOI: 10.1261/Rna.056895.116  0.408
2016 Irani S, Pan X, Peck BC, Iqbal J, Sethupathy P, Hussain MM. MicroRNA-30c Mimic Mitigates Hypercholesterolemia and Atherosclerosis in Mice. The Journal of Biological Chemistry. PMID 27365390 DOI: 10.1074/Jbc.M116.728451  0.339
2016 Sollome J, Martin E, Sethupathy P, Fry RC. Environmental Contaminants and microRNA Regulation: Transcription Factors as Regulators of Toxicant-Altered microRNA Expression. Toxicology and Applied Pharmacology. PMID 27292125 DOI: 10.1016/J.Taap.2016.06.009  0.406
2016 Peck BC, Sincavage J, Feinstein S, Mah AT, Simmons JG, Lund PK, Sethupathy P. miR-30 family controls proliferation and differentiation of intestinal epithelial cell models by directing a broad gene expression program that includes SOX9 and the ubiquitin ligase pathway. The Journal of Biological Chemistry. PMID 27261459 DOI: 10.1074/Jbc.M116.733733  0.446
2016 Sethupathy P. The Promise and Challenge of Therapeutic MicroRNA Silencing in Diabetes and Metabolic Diseases. Current Diabetes Reports. 16: 52. PMID 27112956 DOI: 10.1007/S11892-016-0745-3  0.411
2015 Baran-Gale J, Kurtz CL, Erdos MR, Sison C, Young A, Fannin EE, Chines PS, Sethupathy P. Addressing Bias in Small RNA Library Preparation for Sequencing: A New Protocol Recovers MicroRNAs that Evade Capture by Current Methods. Frontiers in Genetics. 6: 352. PMID 26734062 DOI: 10.3389/Fgene.2015.00352  0.388
2015 Selitsky SR, Dinh TA, Toth CL, Kurtz CL, Honda M, Struck BR, Kaneko S, Vickers KC, Lemon SM, Sethupathy P. Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs. Mbio. 6. PMID 26646011 DOI: 10.1128/Mbio.01500-15  0.434
2015 Roman TS, Marvelle AF, Fogarty MP, Vadlamudi S, Gonzalez AJ, Buchkovich ML, Huyghe JR, Fuchsberger C, Jackson AU, Wu Y, Civelek M, Lusis AJ, Gaulton KJ, Sethupathy P, Kangas AJ, et al. Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol. American Journal of Human Genetics. 97: 801-15. PMID 26637976 DOI: 10.1016/J.Ajhg.2015.10.016  0.309
2015 Rutledge H, Baran-Gale J, de Villena FP, Chesler EJ, Churchill GA, Sethupathy P, Kelada SN. Identification of microRNAs associated with allergic airway disease using a genetically diverse mouse population. Bmc Genomics. 16: 633. PMID 26303911 DOI: 10.1186/S12864-015-1732-9  0.446
2015 Kurtz CL, Fannin EE, Toth CL, Pearson DS, Vickers KC, Sethupathy P. Inhibition of miR-29 has a significant lipid-lowering benefit through suppression of lipogenic programs in liver. Scientific Reports. 5: 12911. PMID 26246194 DOI: 10.1038/Srep12911  0.394
2015 Peck BC, Weiser M, Lee SE, Gipson GR, Iyer VB, Sartor RB, Herfarth HH, Long MD, Hansen JJ, Isaacs KL, Trembath DG, Rahbar R, Sadiq TS, Furey TS, Sethupathy P, et al. MicroRNAs Classify Different Disease Behavior Phenotypes of Crohn's Disease and May Have Prognostic Utility. Inflammatory Bowel Diseases. PMID 26164662 DOI: 10.1097/Mib.0000000000000478  0.34
2015 Welch JD, Baran-Gale J, Perou CM, Sethupathy P, Prins JF. Pseudogenes transcribed in breast invasive carcinoma show subtype-specific expression and ceRNA potential. Bmc Genomics. 16: 113. PMID 25765044 DOI: 10.1186/S12864-015-1227-8  0.367
2014 Vickers KC, Landstreet SR, Levin MG, Shoucri BM, Toth CL, Taylor RC, Palmisano BT, Tabet F, Cui HL, Rye KA, Sethupathy P, Remaley AT. MicroRNA-223 coordinates cholesterol homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 111: 14518-23. PMID 25246565 DOI: 10.1073/Pnas.1215767111  0.396
2014 Vencken SF, Sethupathy P, Blackshields G, Spillane C, Elbaruni S, Sheils O, Gallagher MF, O'Leary JJ. An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines. Bmc Genomics. 15: 711. PMID 25156079 DOI: 10.1186/1471-2164-15-711  0.387
2014 Collins AL, Kim Y, Bloom RJ, Kelada SN, Sethupathy P, Sullivan PF. Transcriptional targets of the schizophrenia risk gene MIR137. Translational Psychiatry. 4: e404. PMID 24984191 DOI: 10.1038/Tp.2014.42  0.367
2014 Kurtz CL, Peck BC, Fannin EE, Beysen C, Miao J, Landstreet SR, Ding S, Turaga V, Lund PK, Turner S, Biddinger SB, Vickers KC, Sethupathy P. MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes. Diabetes. 63: 3141-8. PMID 24722248 DOI: 10.2337/Db13-1015  0.42
2014 Tabet F, Vickers KC, Cuesta Torres LF, Wiese CB, Shoucri BM, Lambert G, Catherinet C, Prado-Lourenco L, Levin MG, Thacker S, Sethupathy P, Barter PJ, Remaley AT, Rye KA. HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells. Nature Communications. 5: 3292. PMID 24576947 DOI: 10.1038/Ncomms4292  0.379
2013 Baran-Gale J, Fannin EE, Kurtz CL, Sethupathy P. Beta cell 5'-shifted isomiRs are candidate regulatory hubs in type 2 diabetes. Plos One. 8: e73240. PMID 24039891 DOI: 10.1371/Journal.Pone.0073240  0.442
2013 Sethupathy P. Illuminating microRNA Transcription from the Epigenome. Current Genomics. 14: 68-77. PMID 23997652 DOI: 10.2174/138920213804999183  0.419
2013 Kelada S, Sethupathy P, Okoye IS, Kistasis E, Czieso S, White SD, Chou D, Martens C, Ricklefs SM, Virtaneva K, Sturdevant DE, Porcella SF, Belkaid Y, Wynn TA, Wilson MS. miR-182 and miR-10a are key regulators of Treg specialisation and stability during Schistosome and Leishmania-associated inflammation. Plos Pathogens. 9: e1003451. PMID 23825948 DOI: 10.1371/Journal.Ppat.1003451  0.395
2013 Bulik-Sullivan B, Selitsky S, Sethupathy P. Prioritization of genetic variants in the microRNA regulome as functional candidates in genome-wide association studies. Human Mutation. 34: 1049-56. PMID 23595788 DOI: 10.1002/Humu.22337  0.44
2013 Vickers KC, Sethupathy P, Baran-Gale J, Remaley AT. Complexity of microRNA function and the role of isomiRs in lipid homeostasis. Journal of Lipid Research. 54: 1182-91. PMID 23505317 DOI: 10.1194/Jlr.R034801  0.401
2013 Sethupathy P. Needles in the genetic haystack of lipid disorders: single nucleotide polymorphisms in the microRNA regulome. Journal of Lipid Research. 54: 1168-73. PMID 23505316 DOI: 10.1194/Jlr.R035766  0.42
2013 Peters U, North KE, Sethupathy P, Buyske S, Haessler J, Jiao S, Fesinmeyer MD, Jackson RD, Kuller LH, Rajkovic A, Lim U, Cheng I, Schumacher F, Wilkens L, Li R, et al. A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study. Plos Genetics. 9: e1003171. PMID 23341774 DOI: 10.1371/Journal.Pgen.1003171  0.3
2013 Vickers KC, Shoucri BM, Levin MG, Wu H, Pearson DS, Osei-Hwedieh D, Collins FS, Remaley AT, Sethupathy P. MicroRNA-27b is a regulatory hub in lipid metabolism and is altered in dyslipidemia. Hepatology (Baltimore, Md.). 57: 533-42. PMID 22777896 DOI: 10.1002/Hep.25846  0.439
2012 Bonner SM, Pietropaolo SL, Fan Y, Chang Y, Sethupathy P, Morran MP, Beems M, Giannoukakis N, Trucco G, Palumbo MO, Solimena M, Pugliese A, Polychronakos C, Trucco M, Pietropaolo M. Sequence variation in promoter of Ica1 gene, which encodes protein implicated in type 1 diabetes, causes transcription factor autoimmune regulator (AIRE) to increase its binding and down-regulate expression. The Journal of Biological Chemistry. 287: 17882-93. PMID 22447927 DOI: 10.1074/Jbc.M111.319020  0.325
2012 Valdmanis PN, Gu S, Schüermann N, Sethupathy P, Grimm D, Kay MA. Expression determinants of mammalian argonaute proteins in mediating gene silencing. Nucleic Acids Research. 40: 3704-13. PMID 22210886 DOI: 10.1093/Nar/Gkr1274  0.326
2011 Melgar MF, Collins FS, Sethupathy P. Discovery of active enhancers through bidirectional expression of short transcripts. Genome Biology. 12: R113. PMID 22082242 DOI: 10.1186/Gb-2011-12-11-R113  0.332
2011 Stone N, Pangilinan F, Molloy AM, Shane B, Scott JM, Ueland PM, Mills JL, Kirke PN, Sethupathy P, Brody LC. Bioinformatic and genetic association analysis of microRNA target sites in one-carbon metabolism genes. Plos One. 6: e21851. PMID 21765920 DOI: 10.1371/Journal.Pone.0021851  0.358
2011 Vishnoi A, Sethupathy P, Simola D, Plotkin JB, Hannenhalli S. Genome-wide survey of natural selection on functional, structural, and network properties of polymorphic sites in Saccharomyces paradoxus. Molecular Biology and Evolution. 28: 2615-27. PMID 21478372 DOI: 10.1093/Molbev/Msr085  0.507
2010 Megraw M, Sethupathy P, Gumireddy K, Jensen ST, Huang Q, Hatzigeorgiou AG. Isoform specific gene auto-regulation via miRNAs: A case study on miR-128b and ARPP-21 Theoretical Chemistry Accounts. 125: 593-598. DOI: 10.1007/S00214-009-0647-4  0.315
2008 Sethupathy P, Hannenhalli S. A tutorial of the poisson random field model in population genetics. Advances in Bioinformatics. 257864. PMID 19920987 DOI: 10.1155/2008/257864  0.499
2008 Sethupathy P, Giang H, Plotkin JB, Hannenhalli S. Genome-wide analysis of natural selection on human cis-elements. Plos One. 3: e3137. PMID 18781197 DOI: 10.1371/Journal.Pone.0003137  0.514
2008 Sethupathy P, Collins FS. MicroRNA target site polymorphisms and human disease. Trends in Genetics : Tig. 24: 489-97. PMID 18778868 DOI: 10.1016/J.Tig.2008.07.004  0.314
2007 Sethupathy P, Borel C, Gagnebin M, Grant GR, Deutsch S, Elton TS, Hatzigeorgiou AG, Antonarakis SE. Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3' untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypes. American Journal of Human Genetics. 81: 405-13. PMID 17668390 DOI: 10.1086/519979  0.312
2007 Kawahara Y, Zinshteyn B, Sethupathy P, Iizasa H, Hatzigeorgiou AG, Nishikura K. Redirection of silencing targets by adenosine-to-inosine editing of miRNAs. Science (New York, N.Y.). 315: 1137-40. PMID 17322061 DOI: 10.1126/science.1138050  0.334
2007 Megraw M, Sethupathy P, Corda B, Hatzigeorgiou AG. miRGen: a database for the study of animal microRNA genomic organization and function. Nucleic Acids Research. 35: D149-55. PMID 17108354 DOI: 10.1093/Nar/Gkl904  0.38
Low-probability matches (unlikely to be authored by this person)
2019 Furey TS, Sethupathy P, Sheikh SZ. Redefining the IBDs using genome-scale molecular phenotyping. Nature Reviews. Gastroenterology & Hepatology. PMID 30787446 DOI: 10.1038/S41575-019-0118-X  0.3
2019 Bajinting A, Seiler K, Kanke M, Shanahan MT, Sethupathy P, Warner BW. Su1091 – Subepithelial Microrna Expression During Adaptation to Massive Small Bowel Resection Gastroenterology. 156: S-1436-S-1437. DOI: 10.1016/S0016-5085(19)40642-2  0.299
2021 Shanahan M, Kanke M, Oyesola OO, Hung YH, Koch-Laskowski K, Singh AP, Peck BCE, Biraud M, Sheahan B, Cortes JE, Gong H, Sahoo DK, Cubitt R, Kurpios NA, Mochel JP, ... ... Sethupathy P, et al. Multi-omic analysis defines the first microRNA atlas across all small intestinal epithelial lineages and reveals novel markers of almost all major cell types. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 34643097 DOI: 10.1152/ajpgi.00222.2021  0.298
2006 Gupta A, Gartner JJ, Sethupathy P, Hatzigeorgiou AG, Fraser NW. Anti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcript. Nature. 442: 82-5. PMID 16738545 DOI: 10.1038/Nature04836  0.296
2008 Zhang L, Volinia S, Bonome T, Calin GA, Greshock J, Yang N, Liu CG, Giannakakis A, Alexiou P, Hasegawa K, Johnstone CN, Megraw MS, Adams S, Lassus H, Huang J, ... ... Sethupathy P, et al. Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America. 105: 7004-9. PMID 18458333 DOI: 10.1073/Pnas.0801615105  0.296
2012 Avery CL, Sethupathy P, Buyske S, He Q, Lin DY, Arking DE, Carty CL, Duggan D, Fesinmeyer MD, Hindorff LA, Jeff JM, Klein L, Patton KK, Peters U, Shohet RV, et al. Fine-mapping and initial characterization of QT interval loci in African Americans. Plos Genetics. 8: e1002870. PMID 22912591 DOI: 10.1371/Journal.Pgen.1002870  0.296
2021 Smith GJ, Tovar A, Kanke M, Wang Y, Deshane JS, Sethupathy P, Kelada SNP. Ozone-induced changes in the murine lung extracellular vesicle small RNA landscape. Physiological Reports. 9: e15054. PMID 34558223 DOI: 10.14814/phy2.15054  0.294
2019 Yamane D, Feng H, Rivera-Serrano EE, Selitsky SR, Hirai-Yuki A, Das A, McKnight KL, Misumi I, Hensley L, Lovell W, González-López O, Suzuki R, Matsuda M, Nakanishi H, Ohto-Nakanishi T, ... ... Sethupathy P, et al. Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses. Nature Microbiology. PMID 30988429 DOI: 10.1038/S41564-019-0425-6  0.292
2013 Paredes SH, Melgar MF, Sethupathy P. Promoter-proximal CCCTC-factor binding is associated with an increase in the transcriptional pausing index. Bioinformatics (Oxford, England). 29: 1485-7. PMID 23047559 DOI: 10.1093/Bioinformatics/Bts596  0.291
2006 Sethupathy P, Corda B, Hatzigeorgiou AG. TarBase: A comprehensive database of experimentally supported animal microRNA targets. Rna (New York, N.Y.). 12: 192-7. PMID 16373484 DOI: 10.1261/rna.2239606  0.291
2022 Villanueva JW, Kwong L, Han T, Martinez SA, Shanahan MT, Kanke M, Dow LE, Danko CG, Sethupathy P. Comprehensive microRNA analysis across genome-edited colorectal cancer organoid models reveals miR-24 as a candidate regulator of cell survival. Bmc Genomics. 23: 792. PMID 36457077 DOI: 10.1186/s12864-022-09018-1  0.29
2012 Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP, Ferrara A, ... ... Sethupathy P, et al. A genome-wide association search for type 2 diabetes genes in African Americans. Plos One. 7: e29202. PMID 22238593 DOI: 10.1371/Journal.Pone.0029202  0.289
2009 Maragkakis M, Alexiou P, Papadopoulos GL, Reczko M, Dalamagas T, Giannopoulos G, Goumas G, Koukis E, Kourtis K, Simossis VA, Sethupathy P, Vergoulis T, Koziris N, Sellis T, Tsanakas P, et al. Accurate microRNA target prediction correlates with protein repression levels. Bmc Bioinformatics. 10: 295. PMID 19765283 DOI: 10.1186/1471-2105-10-295  0.287
2019 Hennessy EJ, van Solingen C, Scacalossi KR, Ouimet M, Afonso MS, Prins J, Koelwyn GJ, Sharma M, Ramkhelawon B, Carpenter S, Busch A, Chernogubova E, Matic LP, Hedin U, Maegdefessel L, ... ... Sethupathy P, et al. The long noncoding RNA CHROME regulates cholesterol homeostasis in primate. Nature Metabolism. 1: 98-110. PMID 31410392 DOI: 10.1038/s42255-018-0004-9  0.286
2018 Keith BP, Barrow JB, Toyonaga T, Kazgan N, O'Connor MH, Shah ND, Schaner MS, Wolber EA, Trad OK, Gipson GR, Pitman WA, Kanke M, Saxena SJ, Chaumont N, Sadiq TS, ... ... Sethupathy P, et al. Colonic epithelial miR-31 associates with the development of Crohn's phenotypes. Jci Insight. 3. PMID 30282822 DOI: 10.1172/Jci.Insight.122788  0.283
2023 Hung YH, Capeling M, Villanueva JW, Kanke M, Shanahan MT, Huang S, Cubitt R, Rinaldi VD, Schimenti JC, Spence JR, Sethupathy P. Integrative genome-scale analyses reveal post-transcriptional signatures of early human small intestinal development in a directed differentiation organoid model. Bmc Genomics. 24: 641. PMID 37884859 DOI: 10.1186/s12864-023-09743-1  0.281
2015 Selitsky SR, Baran-Gale J, Honda M, Yamane D, Masaki T, Fannin EE, Guerra B, Shirasaki T, Shimakami T, Kaneko S, Lanford RE, Lemon SM, Sethupathy P. Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C. Scientific Reports. 5: 7675. PMID 25567797 DOI: 10.1038/Srep07675  0.281
2022 Miller JL, Kanke M, Rauner G, Bakhle KM, Sethupathy P, Van de Walle GR. Comparative Analysis of microRNAs that Stratify in vitro Mammary stem and Progenitor Activity Reveals Functionality of Human miR-92b-3p. Journal of Mammary Gland Biology and Neoplasia. PMID 36190643 DOI: 10.1007/s10911-022-09525-7  0.281
2019 Hennessy EJ, van Solingen C, Scacalossi KR, Ouimet M, Afonso MS, Prins J, Koelwyn GJ, Sharma M, Ramkhelawon B, Carpenter S, Busch A, Chernogubova E, Matic LP, Hedin U, Maegdefessel L, ... ... Sethupathy P, et al. The long noncoding RNA CHROME regulates cholesterol homeostasis in primates. Nature Metabolism. 1: 98-110. PMID 32694807 DOI: 10.1038/s42255-018-0004-9  0.281
2015 Reid LM, Sethupathy P. The DNAJB1-PRKACA chimera: Candidate biomarker and therapeutic target for fibrolamellar carcinomas. Hepatology (Baltimore, Md.). PMID 26505878 DOI: 10.1002/Hep.28307  0.281
2021 Wang X, Zhang W, Yang Y, Wang J, Qiu H, Liao L, Oikawa T, Wauthier E, Sethupathy P, Reid LM, Liu Z, He Z. A MicroRNA-Based Network Provides Potential Predictive Signatures and Reveals the Crucial Role of PI3K/AKT Signaling for Hepatic Lineage Maturation. Frontiers in Cell and Developmental Biology. 9: 670059. PMID 34141708 DOI: 10.3389/fcell.2021.670059  0.28
2013 Furey TS, Sethupathy P. Genetics. Genetics driving epigenetics. Science (New York, N.Y.). 342: 705-6. PMID 24202168 DOI: 10.1126/Science.1246755  0.279
2024 Shumway AJ, Shanahan MT, Hollville E, Chen K, Beasley C, Villanueva JW, Albert S, Lian G, Cure MR, Schaner M, Zhu LC, Bantumilli S, Deshmukh M, Furey TS, Sheikh SZ, ... Sethupathy P, et al. Aberrant miR-29 is a predictive feature of severe phenotypes in pediatric Crohn's disease. Jci Insight. 9. PMID 38385744 DOI: 10.1172/jci.insight.168800  0.279
2020 Thielen LA, Chen J, Jing G, Moukha-Chafiq O, Xu G, Jo S, Grayson TB, Lu B, Li P, Augelli-Szafran CE, Suto MJ, Kanke M, Sethupathy P, Kim JK, Shalev A. Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action. Cell Metabolism. PMID 32726606 DOI: 10.1016/J.Cmet.2020.07.002  0.278
2017 Hung YH, Sethupathy P. Important Considerations for Studies of Circulating MicroRNAs in Clinical Samples. Ebiomedicine. PMID 28988980 DOI: 10.1016/J.Ebiom.2017.09.030  0.276
2009 Papadopoulos GL, Reczko M, Simossis VA, Sethupathy P, Hatzigeorgiou AG. The database of experimentally supported targets: a functional update of TarBase. Nucleic Acids Research. 37: D155-8. PMID 18957447 DOI: 10.1093/nar/gkn809  0.274
2010 Stitzel ML, Sethupathy P, Pearson DS, Chines PS, Song L, Erdos MR, Welch R, Parker SCJ, Boyle AP, Scott LJ, Program NCS, Margulies EH, Boehnke M, Furey TS, Crawford GE, et al. Erratum: Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci (Cell Metabolism (2010) 12 (443-455)) Cell Metabolism. 12. DOI: 10.1016/J.Cmet.2010.11.013  0.274
2019 Hung YH, Kanke M, Kurtz CL, Cubitt RL, Bunaciu RP, Zhou L, White PJ, Vickers KC, Hussain MM, Li X, Sethupathy P. MiR-29 Regulates Lipogenesis in the Liver and Circulating Triglyceride Levels in a Sirt1-Dependent Manner. Frontiers in Physiology. 10: 1367. PMID 31736786 DOI: 10.3389/Fphys.2019.01367  0.271
2019 Hung YH, Kanke M, Kurtz CL, Cubitt RL, Bunaciu RP, Zhou L, White PJ, Vickers KC, Hussain MM, Li X, Sethupathy P. MiR-29 Regulates Lipogenesis in the Liver and Circulating Triglyceride Levels in a Sirt1-Dependent Manner. Frontiers in Physiology. 10: 1367. PMID 31736786 DOI: 10.3389/Fphys.2019.01367  0.271
2017 Key CC, Liu M, Kurtz CL, Chung S, Boudyguina E, Dinh TA, Bashore A, Phelan PE, Freedman BI, Osborne TF, Zhu X, Ma L, Sethupathy P, Biddinger SB, Parks JS. Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis. Cell Reports. 19: 2116-2129. PMID 28591582 DOI: 10.1016/J.Celrep.2017.05.032  0.268
2019 Butler AA, Price CA, Graham JL, Stanhope KL, King S, Hung YH, Sethupathy P, Wong S, Hamilton J, Krauss RM, Bremer AA, Havel PJ. Fructose-induced hypertriglyceridemia in rhesus macaques is attenuated with fish oil or apoC3 RNA interference. Journal of Lipid Research. PMID 30723097 DOI: 10.1194/Jlr.M089508  0.265
2014 Franceschini N, Hu Y, Reiner AP, Buyske S, Nalls M, Yanek LR, Li Y, Hindorff LA, Cole SA, Howard BV, Stafford JM, Carty CL, Sethupathy P, Martin LW, Lin DY, et al. Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study. Plos One. 9: e113203. PMID 25542012 DOI: 10.1371/Journal.Pone.0113203  0.265
2013 Sethupathy P, Rubin DB, Li G, Cleland TA. A model of electrophysiological heterogeneity in periglomerular cells. Frontiers in Computational Neuroscience. 7: 49. PMID 23637658 DOI: 10.3389/Fncom.2013.00049  0.264
2017 Peck BCE, Shanahan MT, Singh AP, Sethupathy P. Gut Microbial Influences on the Mammalian Intestinal Stem Cell Niche. Stem Cells International. 2017: 5604727. PMID 28904533 DOI: 10.1155/2017/5604727  0.261
2017 Beck R, Styblo M, Sethupathy P. Arsenic Exposure and Type 2 Diabetes: MicroRNAs as Mechanistic Links? Current Diabetes Reports. 17: 18. PMID 28275977 DOI: 10.1007/S11892-017-0845-8  0.258
2015 Oikawa T, Wauthier E, Dinh TA, Selitsky SR, Reyna-Neyra A, Carpino G, Levine R, Cardinale V, Klimstra D, Gaudio E, Alvaro D, Carrasco N, Sethupathy P, Reid LM. Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells. Nature Communications. 6: 8070. PMID 26437858 DOI: 10.1038/Ncomms9070  0.257
2015 Selitsky SR, Sethupathy P. tDRmapper: challenges and solutions to mapping, naming, and quantifying tRNA-derived RNAs from human small RNA-sequencing data. Bmc Bioinformatics. 16: 354. PMID 26530785 DOI: 10.1186/S12859-015-0800-0  0.255
2017 Ghoshal S, Stevens JR, Billon C, Girardet C, Sitaula S, Leon AS, Rao DC, Skinner JS, Rankinen T, Bouchard C, Nuñez MV, Stanhope KL, Howatt DA, Daugherty A, Zhang J, ... ... Sethupathy P, et al. Adropin: An endocrine link between the biological clock and cholesterol homeostasis. Molecular Metabolism. PMID 29331507 DOI: 10.1016/J.Molmet.2017.12.002  0.255
2010 Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, ... ... Sethupathy P, et al. Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk Nature Genetics. 42: 464-464. DOI: 10.1038/Ng0510-464A  0.247
2015 Swahari V, Nakamura A, Baran-Gale J, Garcia I, Crowther AJ, Sons R, Gershon TR, Hammond S, Sethupathy P, Deshmukh M. Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum. Cell Reports. PMID 26748703 DOI: 10.1016/J.Celrep.2015.12.037  0.241
2023 Harman RM, Das SP, Kanke M, Sethupathy P, Van de Walle GR. miRNA-214-3p stimulates carcinogen-induced mammary epithelial cell apoptosis in mammary cancer-resistant species. Communications Biology. 6: 1006. PMID 37789172 DOI: 10.1038/s42003-023-05370-4  0.238
2022 Todero JE, Koch-Laskowski K, Shi Q, Kanke M, Hung YH, Beck R, Styblo M, Sethupathy P. Candidate master microRNA regulator of arsenic-induced pancreatic beta cell impairment revealed by multi-omics analysis. Archives of Toxicology. PMID 35314868 DOI: 10.1007/s00204-022-03263-9  0.236
2016 Kanke M, Baran-Gale J, Villanueva J, Sethupathy P. miRquant 2.0: an Expanded Tool for Accurate Annotation and Quantification of MicroRNAs and their isomiRs from Small RNA-Sequencing Data. Journal of Integrative Bioinformatics. 13: 47-56. PMID 29216002 DOI: 10.1515/jib-2016-307  0.234
2019 Garibay D, Zaborska KE, Shanahan M, Zheng Q, Kelly KM, Montrose DC, Dannenberg AJ, Miller AD, Sethupathy P, Cummings BP. TGR5 Protects Against Colitis in Mice, but Vertical Sleeve Gastrectomy Increases Colitis Severity. Obesity Surgery. PMID 30623320 DOI: 10.1007/S11695-019-03707-9  0.231
2023 Iyer DR, Arige V, Ananthamohan K, Sundaramurthy V, Tokinoya K, Aoki K, Kurtz CL, Sethupathy P, Takekoshi K, Mahapatra NR. Cyclic-AMP response element binding protein (CREB) and microRNA miR-29b regulate renalase gene expression under catecholamine excess conditions. Life Sciences. 328: 121859. PMID 37315838 DOI: 10.1016/j.lfs.2023.121859  0.225
2007 Sethupathy P, Megraw M, Hatzigeorgiou AG. Computational approaches to elucidate miRNA biology Micrornas: From Basic Science to Disease Biology. 187-198. DOI: 10.1017/CBO9780511541766.016  0.223
2020 Zhang W, Allen A, Wauthier E, Yi X, Hani H, Sethupathy P, Gerber D, Cardinale V, Carpino G, Dominguez‐Bendala J, Lanzoni G, Alvaro D, Gaudio E, Reid L. Stem Cell‐Fueled Maturational Lineages in Hepatic and Pancreatic Organogenesis Liver. 521-538. DOI: 10.1002/9781119436812.Ch42  0.222
2006 Sethupathy P, Megraw M, Hatzigeorgiou AG. A guide through present computational approaches for the identification of mammalian microRNA targets. Nature Methods. 3: 881-6. PMID 17060911 DOI: 10.1038/nmeth954  0.222
2020 Toyonaga T, Keith B, Barrow J, Schaner M, Wolber E, Beasley C, Huling J, Wang Y, Allbritton N, Furey T, Sethupathy P, Sheikh S. P149 DECREASED COLONIC ACTIVIN RECEPTOR-LIKE KINASE 1 DISRUPTS EPITHELIAL BARRIER INTEGRITY AND IS ASSOCIATED WITH A POOR CLINICAL OUTCOME IN CROHN’S DISEASE Gastroenterology. 158: S46. DOI: 10.1053/J.Gastro.2019.11.133  0.221
2010 Stitzel ML, Sethupathy P, Pearson DS, Chines PS, Song L, Erdos MR, Welch R, Parker SC, Boyle AP, Scott LJ, Margulies EH, Boehnke M, Furey TS, Crawford GE, et al. Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci. Cell Metabolism. 12: 443-55. PMID 21035756 DOI: 10.1016/J.Cmet.2010.09.012  0.203
2006 Cleland TA, Sethupathy P. Non-topographical contrast enhancement in the olfactory bulb. Bmc Neuroscience. 7: 7. PMID 16433921 DOI: 10.1186/1471-2202-7-7  0.194
2022 Xu G, Grimes TD, Grayson TB, Chen J, Thielen LA, Tse HM, Li P, Kanke M, Lin TT, Schepmoes AA, Swensen AC, Petyuk VA, Ovalle F, Sethupathy P, Qian WJ, et al. Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes. Nature Communications. 13: 1159. PMID 35241690 DOI: 10.1038/s41467-022-28826-3  0.188
2009 Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, Manolio TA. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proceedings of the National Academy of Sciences of the United States of America. 106: 9362-7. PMID 19474294 DOI: 10.1073/Pnas.0903103106  0.181
2023 Liu S, Benito-Martin A, Pelissier Vatter FA, Hanif SZ, Liu C, Bhardwaj P, Sethupathy P, Farghli AR, Piloco P, Paik P, Mushannen M, Dong X, Otterburn DM, Cohen L, Bareja R, et al. Breast adipose tissue-derived extracellular vesicles from obese women alter tumor cell metabolism. Embo Reports. e57339. PMID 37929643 DOI: 10.15252/embr.202357339  0.179
2023 Liu S, Benito-Martin A, Pelissier Vatter FA, Hanif SZ, Liu C, Bhardwaj P, Sethupathy P, Farghli AR, Piloco P, Paik P, Mushannen M, Otterburn DM, Cohen L, Bareja R, Krumsiek J, et al. Breast adipose tissue-derived extracellular vesicles from women with obesity stimulate mitochondrial-induced dysregulated tumor cell metabolism. Biorxiv : the Preprint Server For Biology. PMID 36798307 DOI: 10.1101/2023.02.08.527715  0.176
2024 Koch-Laskowski K, Kim KS, Bethea M, Fuller KNZ, Sandoval DA, Sethupathy P. Intestinal epithelial adaptations to vertical sleeve gastrectomy defined at single-cell resolution. Genomics. 110805. PMID 38309446 DOI: 10.1016/j.ygeno.2024.110805  0.173
2005 Sethupathy P, Megraw M, Barrasa MI, Hatzigeorgiou AG. Computational identification of regulatory factors involved in MicroRNA transcription Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 3746: 457-468. DOI: 10.1007/11573036_43  0.171
2021 Swahari V, Nakamura A, Hollville E, Stroud H, Simon JM, Ptacek TS, Beck MV, Flowers C, Guo J, Plestant C, Liang J, Kurtz CL, Kanke M, Hammond SM, He YW, ... ... Sethupathy P, et al. MicroRNA-29 is an essential regulator of brain maturation through regulation of CH methylation. Cell Reports. 35: 108946. PMID 33826889 DOI: 10.1016/j.celrep.2021.108946  0.167
2024 Ma RK, Tsai PY, Farghli AR, Shumway A, Kanke M, Gordan JD, Gujral TS, Vakili K, Nukaya M, Noetzli L, Ronnekleiv-Kelly S, Broom W, Barrow J, Sethupathy P. DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma. Plos Genetics. 20: e1011216. PMID 38512964 DOI: 10.1371/journal.pgen.1011216  0.167
2022 Kim KS, Peck BC, Hung YH, Koch-Laskowski K, Wood L, Dedhia PH, Spence JR, Seeley RJ, Sethupathy P, Sandoval DA. Vertical sleeve gastrectomy induces enteroendocrine cell differentiation of intestinal stem cells through bile acid signaling. Jci Insight. PMID 35503251 DOI: 10.1172/jci.insight.154302  0.165
2022 Kim SS, Kycia I, Karski M, Ma RK, Bordt EA, Kwan J, Karki A, Winter E, Aktas RG, Wu Y, Emili A, Bauer DE, Sethupathy P, Vakili K. DNAJB1-PRKACA in HEK293T cells induces LINC00473 overexpression that depends on PKA signaling. Plos One. 17: e0263829. PMID 35167623 DOI: 10.1371/journal.pone.0263829  0.164
2021 Hung YH, Huang S, Dame MK, Yu Q, Yu QC, Zeng YA, Camp JG, Spence JR, Sethupathy P. Chromatin regulatory dynamics of early human small intestinal development using a directed differentiation model. Nucleic Acids Research. PMID 33406262 DOI: 10.1093/nar/gkaa1204  0.155
2024 Gershon Z, Bonito-Oliva A, Kanke M, Terceros A, Rankin G, Fak J, Harada Y, Iannone AF, Gebremedhin M, Fabella B, De Marco Garcia NV, Sethupathy P, Rajasethupathy P. Genetic mapping identifies Homer1 as a developmental modifier of attention. Biorxiv : the Preprint Server For Biology. PMID 36993710 DOI: 10.1101/2023.03.17.533136  0.155
2023 Zhang W, Wang X, Lanzoni G, Wauthier E, Simpson S, Ezzell JA, Allen A, Suitt C, Krolik J, Jhirad A, Dominguez-Bendala J, Cardinale V, Alvaro D, Overi D, Gaudio E, ... Sethupathy P, et al. A postnatal network of co-hepato/pancreatic stem/progenitors in the biliary trees of pigs and humans. Npj Regenerative Medicine. 8: 40. PMID 37528116 DOI: 10.1038/s41536-023-00303-5  0.154
2010 Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, ... ... Sethupathy P, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature Genetics. 42: 105-16. PMID 20081858 DOI: 10.1038/Ng.520  0.15
2022 Francisco AB, Li J, Farghli AR, Kanke M, Shui B, Munn PR, Grenier JK, Soloway PD, Wang Z, Reid LM, Liu J, Sethupathy P. Chemical, Molecular, and Single-nucleus Analysis Reveal Chondroitin Sulfate Proteoglycan Aberrancy in Fibrolamellar Carcinoma. Cancer Research Communications. 2: 663-678. PMID 36923282 DOI: 10.1158/2767-9764.CRC-21-0177  0.147
2012 Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, ... ... Sethupathy P, et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. Plos Genetics. 8: e1002607. PMID 22479202 DOI: 10.1371/Journal.Pgen.1002607  0.147
2008 Gartner JJ, Sethupathy P, Hatzigeorgiou AG, Fraser NW. Anti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcript. Nature. 451: 600. PMID 18235505 DOI: 10.1038/Nature06621  0.146
2009 Temple G, Gerhard DS, Rasooly R, Feingold EA, Good PJ, Robinson C, Mandich A, Derge JG, Lewis J, Shoaf D, Collins FS, Jang W, Wagner L, Shenmen CM, ... ... Sethupathy P, et al. The completion of the Mammalian Gene Collection (MGC). Genome Research. 19: 2324-33. PMID 19767417 DOI: 10.1101/Gr.095976.109  0.143
2022 McKellar DW, Mantri M, Hinchman MM, Parker JSL, Sethupathy P, Cosgrove BD, De Vlaminck I. Spatial mapping of the total transcriptome by in situ polyadenylation. Nature Biotechnology. PMID 36329320 DOI: 10.1038/s41587-022-01517-6  0.143
2022 Kanke M, Kennedy Ng MM, Connelly S, Singh M, Schaner M, Shanahan MT, Wolber EA, Beasley C, Lian G, Jain A, Long MD, Barnes EL, Herfarth HH, Isaacs KL, Hansen JJ, ... ... Sethupathy P, et al. Single-cell analysis reveals unexpected cellular changes and transposon expression signatures in the colonic epithelium of treatment-naïve adult Crohn's disease patients. Cellular and Molecular Gastroenterology and Hepatology. PMID 35158099 DOI: 10.1016/j.jcmgh.2022.02.005  0.142
2023 Chan GKL, Maisel S, Hwang YC, Pascual BC, Wolber RRB, Vu P, Patra KC, Bouhaddou M, Kenerson HL, Lim HC, Long D, Yeung RS, Sethupathy P, Swaney DL, Krogan NJ, et al. Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms. Elife. 12. PMID 36692000 DOI: 10.7554/eLife.69521  0.14
2023 Zhang W, Xu Y, Wang X, Oikawa T, Su G, Wauthier E, Wu G, Sethupathy P, He Z, Liu J, Reid LM. Fibrolamellar Carcinomas-Growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 37402431 DOI: 10.1016/j.matbio.2023.06.008  0.135
2021 Oyesola OO, Shanahan MT, Kanke M, Mooney BM, Webb LM, Smita S, Matheson MK, Campioli P, Pham D, Früh SP, McGinty JW, Churchill MJ, Cahoon JL, Sundaravaradan P, Flitter BA, ... ... Sethupathy P, et al. PGD2 and CRTH2 counteract Type 2 cytokine-elicited intestinal epithelial responses during helminth infection. The Journal of Experimental Medicine. 218. PMID 34283207 DOI: 10.1084/jem.20202178  0.133
2023 Xu G, Chen J, Lu B, Sethupathy P, Qian WJ, Shalev A. Verapamil prevents decline of IGF-1 in subjects with T1D and promotes beta-cell IGF-1 signaling. Diabetes. PMID 37494660 DOI: 10.2337/db23-0256  0.126
2022 Dinh TA, Utria AF, Barry KC, Ma R, Abou-Alfa GK, Gordan JD, Jaffee EM, Scott JD, Zucman-Rossi J, O'Neill AF, Furth ME, Sethupathy P. A framework for fibrolamellar carcinoma research and clinical trials. Nature Reviews. Gastroenterology & Hepatology. PMID 35190728 DOI: 10.1038/s41575-022-00580-3  0.121
2023 Todero J, Douillet C, Shumway AJ, Koller BH, Kanke M, Phuong DJ, Stýblo M, Sethupathy P. Molecular and Metabolic Analysis of Arsenic-Exposed Humanized AS3MT Mice. Environmental Health Perspectives. 131: 127021. PMID 38150313 DOI: 10.1289/EHP12785  0.12
2024 Kirk AM, Crawford JC, Chou CH, Guy C, Pandey K, Kozlik T, Shah RK, Chung S, Nguyen P, Zhang X, Wang J, Bell M, Mettelman RC, Allen EK, Pogorelyy MV, ... ... Sethupathy P, et al. DNAJB1-PRKACA fusion neoantigens elicit rare endogenous T cell responses that potentiate cell therapy for fibrolamellar carcinoma. Cell Reports. Medicine. 5: 101469. PMID 38508137 DOI: 10.1016/j.xcrm.2024.101469  0.118
2022 Zhang W, Wauthier E, Lanzoni G, Hani H, Yi X, Overi D, Shi L, Simpson S, Allen A, Suitt C, Ezzell JA, Alvaro D, Cardinale V, Gaudio E, Carpino G, ... ... Sethupathy P, et al. Patch grafting of organoids of stem/progenitors into solid organs can correct genetic-based disease states. Biomaterials. 121647. PMID 36030102 DOI: 10.1016/j.biomaterials.2022.121647  0.117
2022 Cardinale V, Carpino G, Overi D, Safarikia S, Zhang W, Kanke M, Franchitto A, Costantini D, Riccioni O, Nevi L, Chiappetta M, Onori P, Franchitto M, Bini S, Hung YH, ... ... Sethupathy P, et al. Human duodenal submucosal glands contain a defined stem/progenitor subpopulation with liver-specific regenerative potential. Journal of Hepatology. PMID 36089156 DOI: 10.1016/j.jhep.2022.08.037  0.114
2020 Toyonaga T, Araba KC, Kennedy MM, Keith BP, Wolber EA, Beasley C, Steinbach EC, Schaner MR, Jain A, Long MD, Barnes EL, Herfarth HH, Isaacs KL, Hansen JJ, Kapadia M, ... ... Sethupathy P, et al. Increased Colonic Expression of ACE2 Associates with Poor Prognosis in Crohn's disease. Biorxiv : the Preprint Server For Biology. PMID 33269348 DOI: 10.1101/2020.11.24.396382  0.113
2021 Toyonaga T, Araba KC, Kennedy MM, Keith BP, Wolber EA, Beasley C, Steinbach EC, Schaner MR, Jain A, Long MD, Barnes EL, Herfarth HH, Isaacs KL, Hansen JJ, Kapadia MR, ... ... Sethupathy P, et al. Increased colonic expression of ACE2 associates with poor prognosis in Crohn's disease. Scientific Reports. 11: 13533. PMID 34188154 DOI: 10.1038/s41598-021-92979-2  0.106
2021 Zhang W, Lanzoni G, Hani H, Overi D, Cardinale V, Simpson S, Pitman W, Allen A, Yi X, Wang X, Gerber D, Prestwich G, Lozoya O, Gaudio E, Alvaro D, ... ... Sethupathy P, et al. Patch grafting, strategies for transplantation of organoids into solid organs such as liver. Biomaterials. 277: 121067. PMID 34517276 DOI: 10.1016/j.biomaterials.2021.121067  0.1
2021 Hutch CR, Stelmak D, Kanke M, Koch-Laskowski K, Cummings B, Griffin C, Leix K, Sethupathy P, Singer K, Sandoval D. Diet-Dependent Sex Differences in the Response to Vertical Sleeve Gastrectomy. American Journal of Physiology. Endocrinology and Metabolism. PMID 33998293 DOI: 10.1152/ajpendo.00060.2021  0.091
2023 Zhang W, Wang X, Lanzoni G, Wauthier E, Simpson S, Ezzell JA, Allen A, Suitt C, Krolik J, Jhirad A, Dominguez-Bendala J, Cardinale V, Alvaro D, Overi D, Gaudio E, ... Sethupathy P, et al. Publisher Correction: A postnatal network of co-hepato/pancreatic stem/progenitors in the biliary trees of pigs and humans. Npj Regenerative Medicine. 8: 47. PMID 37673918 DOI: 10.1038/s41536-023-00323-1  0.07
2024 Zhang W, Xu Y, Wang X, Oikawa T, Su G, Wauthier E, Wu G, Sethupathy P, He Z, Liu J, Reid LM. Corrigendum to "Fibrolamellar carcinomas-growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides" [Matrix Biology 121(August 2023), 194-216]. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 38565465 DOI: 10.1016/j.matbio.2024.03.004  0.026
2012 Sethupathy P, Alnashef IM, Monnier JR, Matthews MA, Weidner JW. Synthesis of carbonyl compounds from alcohols using electrochemically generated superoxide ions in RTILs Synthetic Communications. 42: 3632-3647. DOI: 10.1080/00397911.2011.587630  0.01
Hide low-probability matches.