Peter G. Gillespie - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Cell Biology, Molecular Biology, Neuroscience Biology

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Spinelli KJ, Gillespie PG. Monitoring intracellular calcium ion dynamics in hair cell populations with Fluo-4 AM. Plos One. 7: e51874. PMID 23284798 DOI: 10.1371/Journal.Pone.0051874  0.47
2012 Ren T, Gillespie PG. Probing the cochlear amplifier by immobilizing molecular motors of sensory hair cells. Neuron. 76: 868-70. PMID 23217736 DOI: 10.1016/J.Neuron.2012.11.016  0.326
2012 Grati M, Shin JB, Weston MD, Green J, Bhat MA, Gillespie PG, Kachar B. Localization of PDZD7 to the stereocilia ankle-link associates this scaffolding protein with the Usher syndrome protein network. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14288-93. PMID 23055499 DOI: 10.1523/Jneurosci.3071-12.2012  0.357
2012 Zhao H, Avenarius MR, Gillespie PG. Improved biolistic transfection of hair cells. Plos One. 7: e46765. PMID 23049715 DOI: 10.1371/Journal.Pone.0046765  0.463
2012 Zhao H, Williams DE, Shin JB, Brügger B, Gillespie PG. Large membrane domains in hair bundles specify spatially constricted radixin activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4600-9. PMID 22457506 DOI: 10.1523/Jneurosci.6184-11.2012  0.381
2012 Zheng QY, Scarborough JD, Zheng Y, Yu H, Choi D, Gillespie PG. Digenic inheritance of deafness caused by 8J allele of myosin-VIIA and mutations in other Usher I genes. Human Molecular Genetics. 21: 2588-98. PMID 22381527 DOI: 10.1093/Hmg/Dds084  0.344
2012 Powers RJ, Roy S, Atilgan E, Brownell WE, Sun SX, Gillespie PG, Spector AA. Stereocilia membrane deformation: implications for the gating spring and mechanotransduction channel. Biophysical Journal. 102: 201-10. PMID 22339856 DOI: 10.1016/J.Bpj.2011.12.022  0.408
2012 Spinelli KJ, Klimek JE, Wilmarth PA, Shin JB, Choi D, David LL, Gillespie PG. Distinct energy metabolism of auditory and vestibular sensory epithelia revealed by quantitative mass spectrometry using MS2 intensity. Proceedings of the National Academy of Sciences of the United States of America. 109: E268-77. PMID 22307652 DOI: 10.1073/Pnas.1115866109  0.328
2011 Maravillas-Montero JL, Gillespie PG, Patiño-López G, Shaw S, Santos-Argumedo L. Myosin 1c participates in B cell cytoskeleton rearrangements, is recruited to the immunologic synapse, and contributes to antigen presentation. Journal of Immunology (Baltimore, Md. : 1950). 187: 3053-63. PMID 21841128 DOI: 10.4049/Jimmunol.1004018  0.406
2011 Borck G, Ur Rehman A, Lee K, Pogoda HM, Kakar N, von Ameln S, Grillet N, Hildebrand MS, Ahmed ZM, Nürnberg G, Ansar M, Basit S, Javed Q, Morell RJ, Nasreen N, ... ... Gillespie PG, et al. Loss-of-function mutations of ILDR1 cause autosomal-recessive hearing impairment DFNB42. American Journal of Human Genetics. 88: 127-37. PMID 21255762 DOI: 10.1016/J.Ajhg.2010.12.011  0.34
2010 Shin JB, Longo-Guess CM, Gagnon LH, Saylor KW, Dumont RA, Spinelli KJ, Pagana JM, Wilmarth PA, David LL, Gillespie PG, Johnson KR. The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9683-94. PMID 20660251 DOI: 10.1523/Jneurosci.1541-10.2010  0.702
2009 Gillespie PG, Müller U. Mechanotransduction by hair cells: models, molecules, and mechanisms. Cell. 139: 33-44. PMID 19804752 DOI: 10.1016/J.Cell.2009.09.010  0.441
2009 Grillet N, Xiong W, Reynolds A, Kazmierczak P, Sato T, Lillo C, Dumont RA, Hintermann E, Sczaniecka A, Schwander M, Williams D, Kachar B, Gillespie PG, Müller U. Harmonin mutations cause mechanotransduction defects in cochlear hair cells. Neuron. 62: 375-87. PMID 19447093 DOI: 10.1016/J.Neuron.2009.04.006  0.741
2009 Spinelli KJ, Gillespie PG. Bottoms up: transduction channels at tip link bases. Nature Neuroscience. 12: 529-30. PMID 19396230 DOI: 10.1038/Nn0509-529  0.377
2009 Shin JB, Gillespie PG. Unraveling cadherin 23's role in development and mechanotransduction. Proceedings of the National Academy of Sciences of the United States of America. 106: 4959-60. PMID 19321743 DOI: 10.1073/Pnas.0902008106  0.47
2009 Shin JB, Pagana J, Gillespie PG. Twist-off purification of hair bundles. Methods in Molecular Biology (Clifton, N.J.). 493: 241-55. PMID 18839351 DOI: 10.1007/978-1-59745-523-7_14  0.341
2008 Müller U, Gillespie P. Silencing the cochlear amplifier by immobilizing prestin. Neuron. 58: 299-301. PMID 18466739 DOI: 10.1016/J.Neuron.2008.04.018  0.368
2007 Iizumi Y, Sagara H, Kabe Y, Azuma M, Kume K, Ogawa M, Nagai T, Gillespie PG, Sasakawa C, Handa H. The enteropathogenic E. coli effector EspB facilitates microvillus effacing and antiphagocytosis by inhibiting myosin function. Cell Host & Microbe. 2: 383-92. PMID 18078690 DOI: 10.1016/J.Chom.2007.09.012  0.355
2007 Karcher RL, Provance DW, Gillespie PG, Mercer JA. Chemical-genetic inhibition of sensitized mutant unconventional myosins. Methods in Molecular Biology (Clifton, N.J.). 392: 231-40. PMID 17951722 DOI: 10.1007/978-1-59745-490-2_16  0.318
2007 Ren T, Gillespie PG. A mechanism for active hearing. Current Opinion in Neurobiology. 17: 498-503. PMID 17707636 DOI: 10.1016/J.Conb.2007.07.013  0.356
2007 Shi X, Gillespie PG, Nuttall AL. Apical phosphatidylserine externalization in auditory hair cells. Molecular Membrane Biology. 24: 16-27. PMID 17453410 DOI: 10.1080/09687860600926883  0.453
2007 Shin JB, Streijger F, Beynon A, Peters T, Gadzala L, McMillen D, Bystrom C, Van der Zee CE, Wallimann T, Gillespie PG. Hair bundles are specialized for ATP delivery via creatine kinase. Neuron. 53: 371-86. PMID 17270734 DOI: 10.1016/J.Neuron.2006.12.021  0.391
2007 LeMasurier M, Gillespie PG. Hair bundles: keeping it together. Nature Neuroscience. 10: 11-2. PMID 17189944 DOI: 10.1038/Nn0107-11  0.504
2006 Gagnon LH, Longo-Guess CM, Berryman M, Shin JB, Saylor KW, Yu H, Gillespie PG, Johnson KR. The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10188-98. PMID 17021174 DOI: 10.1523/Jneurosci.2166-06.2006  0.5
2006 Hill JK, Brett CL, Chyou A, Kallay LM, Sakaguchi M, Rao R, Gillespie PG. Vestibular hair bundles control pH with (Na+, K+)/H+ exchangers NHE6 and NHE9. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9944-55. PMID 17005858 DOI: 10.1523/Jneurosci.2990-06.2006  0.359
2006 Sumoza-Toledo A, Gillespie PG, Romero-Ramirez H, Ferreira-Ishikawa HC, Larson RE, Santos-Argumedo L. Differential localization of unconventional myosin I and nonmuscle myosin II during B cell spreading. Experimental Cell Research. 312: 3312-22. PMID 16919270 DOI: 10.1016/J.Yexcr.2006.07.002  0.349
2006 Hill JK, Williams DE, LeMasurier M, Dumont RA, Strehler EE, Gillespie PG. Splice-site A choice targets plasma-membrane Ca2+-ATPase isoform 2 to hair bundles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6172-80. PMID 16763025 DOI: 10.1523/Jneurosci.0447-06.2006  0.708
2006 Senften M, Schwander M, Kazmierczak P, Lillo C, Shin JB, Hasson T, Géléoc GS, Gillespie PG, Williams D, Holt JR, Müller U. Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2060-71. PMID 16481439 DOI: 10.1523/Jneurosci.4251-05.2006  0.477
2005 LeMasurier M, Gillespie PG. Hair-cell mechanotransduction and cochlear amplification. Neuron. 48: 403-15. PMID 16269359 DOI: 10.1016/J.Neuron.2005.10.017  0.458
2005 Shin JB, Adams D, Paukert M, Siba M, Sidi S, Levin M, Gillespie PG, Gründer S. Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 12572-7. PMID 16116094 DOI: 10.1073/Pnas.0502403102  0.539
2005 Stauffer EA, Scarborough JD, Hirono M, Miller ED, Shah K, Mercer JA, Holt JR, Gillespie PG. Fast adaptation in vestibular hair cells requires myosin-1c activity. Neuron. 47: 541-53. PMID 16102537 DOI: 10.1016/J.Neuron.2005.07.024  0.458
2005 Gillespie PG, Dumont RA, Kachar B. Have we found the tip link, transduction channel, and gating spring of the hair cell? Current Opinion in Neurobiology. 15: 389-96. PMID 16009547 DOI: 10.1016/J.Conb.2005.06.007  0.711
2005 Shi X, Gillespie PG, Nuttall AL. Na+ influx triggers bleb formation on inner hair cells. American Journal of Physiology. Cell Physiology. 288: C1332-41. PMID 15689412 DOI: 10.1152/Ajpcell.00522.2004  0.378
2005 Ronan D, Gillespie P. Metazoan mechanotransduction mystery finally solved Nature Neuroscience. 8: 7-8. PMID 15622409 DOI: 10.1038/Nn0105-7  0.324
2004 Gillespie PG. Myosin I and adaptation of mechanical transduction by the inner ear. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 359: 1945-51. PMID 15647170 DOI: 10.1098/Rstb.2004.1564  0.448
2004 Hirono M, Denis CS, Richardson GP, Gillespie PG. Hair cells require phosphatidylinositol 4,5-bisphosphate for mechanical transduction and adaptation. Neuron. 44: 309-20. PMID 15473969 DOI: 10.1016/J.Neuron.2004.09.020  0.507
2004 Siemens J, Lillo C, Dumont RA, Reynolds A, Williams DS, Gillespie PG, Müller U. Cadherin 23 is a component of the tip link in hair-cell stereocilia. Nature. 428: 950-5. PMID 15057245 DOI: 10.1038/Nature02483  0.738
2004 Gillespie PG, Cyr JL. Myosin-1c, the hair cell's adaptation motor. Annual Review of Physiology. 66: 521-45. PMID 14977412 DOI: 10.1146/Annurev.Physiol.66.032102.112842  0.396
2004 Provance DW, Gourley CR, Silan CM, Cameron LC, Shokat KM, Goldenring JR, Shah K, Gillespie PG, Mercer JA. Chemical-genetic inhibition of a sensitized mutant myosin Vb demonstrates a role in peripheral-pericentriolar membrane traffic. Proceedings of the National Academy of Sciences of the United States of America. 101: 1868-73. PMID 14766983 DOI: 10.1073/Pnas.0305895101  0.341
2003 Hill JK, Gillespie PG. Seeing touch: moving closer to the worm mechanotransduction complex. Current Biology : Cb. 13: R967-9. PMID 14680656 DOI: 10.1016/J.Cub.2003.11.045  0.367
2003 Si F, Brodie H, Gillespie PG, Vazquez AE, Yamoah EN. Developmental assembly of transduction apparatus in chick basilar papilla. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10815-26. PMID 14645474 DOI: 10.1523/Jneurosci.23-34-10815.2003  0.436
2003 Strassmaier M, Gillespie PG. Fast adaptation in the mammalian cochlea: a conserved mechanism for cochlear amplification. Nature Neuroscience. 6: 790-1. PMID 12886223 DOI: 10.1038/Nn0803-790  0.427
2003 Dumont RA, Gillespie PG. Ion channels: hearing aid. Nature. 424: 28-9. PMID 12840745 DOI: 10.1038/424028A  0.682
2002 Dumont RA, Zhao YD, Holt JR, Bähler M, Gillespie PG. Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia. Journal of the Association For Research in Otolaryngology : Jaro. 3: 375-89. PMID 12486594 DOI: 10.1007/S101620020049  0.725
2002 Gillespie PG, Cyr JL. Calmodulin binding to recombinant myosin-1c and myosin-1c IQ peptides. Bmc Biochemistry. 3: 31. PMID 12453307 DOI: 10.1186/1471-2091-3-31  0.314
2002 Strassmaier M, Gillespie PG. The hair cell's transduction channel. Current Opinion in Neurobiology. 12: 380-6. PMID 12139984 DOI: 10.1016/S0959-4388(02)00344-6  0.449
2002 Cyr JL, Dumont RA, Gillespie PG. Myosin-1c interacts with hair-cell receptors through its calmodulin-binding IQ domains. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2487-95. PMID 11923413 DOI: 10.1523/Jneurosci.22-07-02487.2002  0.678
2002 Holt JR, Gillespie SK, Provance DW, Shah K, Shokat KM, Corey DP, Mercer JA, Gillespie PG. A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells. Cell. 108: 371-81. PMID 11853671 DOI: 10.1016/S0092-8674(02)00629-3  0.456
2002 Gillespie PG. Myosin-VIIa and transduction channel tension. Nature Neuroscience. 5: 3-4. PMID 11753408 DOI: 10.1038/Nn0102-3  0.457
2001 Gillespie PG, Walker RG. Molecular basis of mechanosensory transduction. Nature. 413: 194-202. PMID 11557988 DOI: 10.1038/35093011  0.393
2001 Dumont RA, Lins U, Filoteo AG, Penniston JT, Kachar B, Gillespie PG. Plasma membrane Ca2+-ATPase isoform 2a is the PMCA of hair bundles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5066-78. PMID 11438582 DOI: 10.1523/Jneurosci.21-14-05066.2001  0.739
2000 Kachar B, Parakkal M, Kurc M, Zhao Y, Gillespie PG. High-resolution structure of hair-cell tip links. Proceedings of the National Academy of Sciences of the United States of America. 97: 13336-41. PMID 11087873 DOI: 10.1073/Pnas.97.24.13336  0.419
1999 Gillespie PG, Gillespie SK, Mercer JA, Shah K, Shokat KM. Engineering of the myosin-ibeta nucleotide-binding pocket to create selective sensitivity to N(6)-modified ADP analogs. The Journal of Biological Chemistry. 274: 31373-81. PMID 10531338 DOI: 10.1074/Jbc.274.44.31373  0.331
1998 Steyger PS, Gillespie PG, Baird RA. Myosin Ibeta is located at tip link anchors in vestibular hair bundles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4603-15. PMID 9614235  0.368
1998 Yamoah EN, Lumpkin EA, Dumont RA, Smith PJ, Hudspeth AJ, Gillespie PG. Plasma membrane Ca2+-ATPase extrudes Ca2+ from hair cell stereocilia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 610-24. PMID 9425003 DOI: 10.1523/Jneurosci.18-02-00610.1998  0.693
1998 Garcı́a JA, Yee AG, Gillespie PG, Corey DP. Localization of Myosin-Iβ near Both Ends of Tip Links in Frog Saccular Hair Cells The Journal of Neuroscience. 18: 8637-8647. DOI: 10.1523/Jneurosci.18-21-08637.1998  0.343
1998 Steyger PS, Gillespie PG, Baird RA. Myosin Iβ is located at tip link anchors in vestibular hair bundles The Journal of Neuroscience. 18: 4603-4615. DOI: 10.1523/Jneurosci.18-12-04603.1998  0.467
1998 Yamoah EN, Lumpkin EA, Dumont RA, Smith PJS, Hudspeth AJ, Gillespie PG. Plasma Membrane Ca2+-ATPase Extrudes Ca2+from Hair Cell Stereocilia The Journal of Neuroscience. 18: 610-624. DOI: 10.1523/JNEUROSCI.18-02-00610.1998  0.666
1997 Gillespie PG, Corey DP. Myosin and adaptation by hair cells. Neuron. 19: 955-8. PMID 9390509 DOI: 10.1016/S0896-6273(00)80387-6  0.37
1997 Hasson T, Gillespie PG, Garcia JA, MacDonald RB, Zhao Y, Yee AG, Mooseker MS, Corey DP. Unconventional myosins in inner-ear sensory epithelia. The Journal of Cell Biology. 137: 1287-307. PMID 9182663 DOI: 10.1083/Jcb.137.6.1287  0.436
1997 Gillespie PG. Multiple myosin motors and mechanoelectrical transduction by hair cells. The Biological Bulletin. 192: 186-90. PMID 9057290 DOI: 10.2307/1542601  0.509
1996 Gillespie PG, Hasson T, Garcia JA, Corey DP. Multiple myosin isozymes and hair-cell function. Cold Spring Harbor Symposia On Quantitative Biology. 61: 309-18. PMID 9246460 DOI: 10.1101/Sqb.1996.061.01.034  0.424
1996 Zhao Y, Yamoah EN, Gillespie PG. Regeneration of broken tip links and restoration of mechanical transduction in hair cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 15469-74. PMID 8986835 DOI: 10.1073/Pnas.93.26.15469  0.401
1996 Yamoah EN, Gillespie PG. Phosphate analogs block adaptation in hair cells by inhibiting adaptation-motor force production. Neuron. 17: 523-33. PMID 8816715 DOI: 10.1016/S0896-6273(00)80184-1  0.333
1996 Gillespie PG. Feeling force: mechanical transduction by vertebrates and invertebrates. Chemistry & Biology. 3: 223-7. PMID 8807848 DOI: 10.1016/S1074-5521(96)90100-3  0.394
1995 Gillespie PG. Molecular machinery of auditory and vestibular transduction. Current Opinion in Neurobiology. 5: 449-55. PMID 7488845 DOI: 10.1016/0959-4388(95)80004-2  0.47
1994 Hudspeth AJ, Gillespie PG. Pulling springs to tune transduction: adaptation by hair cells. Neuron. 12: 1-9. PMID 8292354 DOI: 10.1016/0896-6273(94)90147-3  0.426
1993 Gillespie PG, Hudspeth AJ. Adenine nucleoside diphosphates block adaptation of mechanoelectrical transduction in hair cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 2710-4. PMID 8464880 DOI: 10.1073/Pnas.90.7.2710  0.389
1993 Gillespie PG, Wagner MC, Hudspeth AJ. Identification of a 120 kd hair-bundle myosin located near stereociliary tips. Neuron. 11: 581-94. PMID 8398149 DOI: 10.1016/0896-6273(93)90071-X  0.432
1993 Walker RG, Hudspeth AJ, Gillespie PG. Calmodulin and calmodulin-binding proteins in hair bundles. Proceedings of the National Academy of Sciences of the United States of America. 90: 2807-11. PMID 8385344 DOI: 10.1073/Pnas.90.7.2807  0.42
1991 Gillespie PG, Hudspeth AJ. High-purity isolation of bullfrog hair bundles and subcellular and topological localization of constituent proteins. The Journal of Cell Biology. 112: 625-40. PMID 1704375 DOI: 10.1083/Jcb.112.4.625  0.394
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