cached image

R. Bruce Merrifield - Publications

Affiliations: 
Rockefeller University, New York, NY, United States 
Area:
Biochemistry
Website:
http://nobelprize.org/nobel_prizes/chemistry/laureates/1984/merrifield.html

162 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 MERRIFIELD RB, MERRIFIELD EL, JUVVADI P, ANDREU D, BOMAN HG. ChemInform Abstract: Design and Synthesis of Antimicrobial Peptides Cheminform. 27: no-no. DOI: 10.1002/chin.199627288  0.419
2010 KAISER E, PICART F, KUBIAK T, TAM JP, MERRIFIELD RB. ChemInform Abstract: Selective Deprotection of the Nα-tert-Butyloxycarbonyl Group in Solid Phase Peptide Synthesis with Chlorotrimethylsilane and Phenol. Cheminform. 25: no-no. DOI: 10.1002/chin.199401270  0.453
2009 Wang S, Merrifield RB. A SOLID PHASE-FRAGMENT APPROACH TO PEPTIDE SYNTHESIS. International Journal of Peptide and Protein Research. 4: 309-318. DOI: 10.1111/j.1399-3011.1972.tb03435.x  0.437
2005 Barany MJ, Hammer RP, Merrifield RB, Barany G. Efficient synthesis of 1,2,4-dithiazolidine-3,5-diones [dithiasuccinoyl-amines] from bis(chlorocarbonyl)disulfane plus bis(trimethylsilyl)amines. Journal of the American Chemical Society. 127: 508-9. PMID 15643859 DOI: 10.1021/Ja0455446  0.569
2001 Robinson NE, Robinson AB, Merrifield RB. Mass spectrometric evaluation of synthetic peptides as primary structure models for peptide and protein deamidation. The Journal of Peptide Research : Official Journal of the American Peptide Society. 57: 483-93. PMID 11437952 DOI: 10.1034/j.1399-3011.2001.00863.x  0.424
1997 Vunnam S, Juvvadi P, Merrifield RB. Synthesis and antibacterial action of cecropin and proline-arginine-rich peptides from pig intestine. The Journal of Peptide Research : Official Journal of the American Peptide Society. 49: 59-66. PMID 9128101 DOI: 10.1111/j.1399-3011.1997.tb01121.x  0.397
1996 Juvvadi P, Vunnam S, Merrifield EL, Boman HG, Merrifield RB. Hydrophobic effects on antibacterial and channel-forming properties of cecropin A-melittin hybrids. Journal of Peptide Science : An Official Publication of the European Peptide Society. 2: 223-32. PMID 9231329 DOI: 10.1002/psc.63  0.344
1995 Merrifield EL, Mitchell SA, Ubach J, Boman HG, Andreu D, Merrifield RB. D-enantiomers of 15-residue cecropin A-melittin hybrids. International Journal of Peptide and Protein Research. 46: 214-20. PMID 8537174 DOI: 10.1111/J.1399-3011.1995.Tb00592.X  0.53
1995 Merrifield RB, Juvvadi P, Andreu D, Ubach J, Boman A, Boman HG. Retro and retroenantio analogs of cecropin-melittin hybrids. Proceedings of the National Academy of Sciences of the United States of America. 92: 3449-53. PMID 7724582 DOI: 10.1073/Pnas.92.8.3449  0.561
1994 Merrifield RB, Merrifield EL, Juvvadi P, Andreu D, Boman HG. Design and synthesis of antimicrobial peptides. Ciba Foundation Symposium. 186: 5-20; discussion 20-. PMID 7768157  0.628
1993 Unson CG, Macdonald D, Merrifield RB. The role of histidine-1 in glucagon action. Archives of Biochemistry and Biophysics. 300: 747-50. PMID 8382034 DOI: 10.1006/abbi.1993.1103  0.503
1993 Kaiser E, Picart F, Kubiak T, Tam JP, Merrifield RB. Selective deprotection of the Nα-tert-butyloxycarbonyl group in solid phase peptide synthesis with chlorotrimethylsilane and phenol Journal of Organic Chemistry. 58: 5167-5175. DOI: 10.1021/Jo00071A028  0.347
1992 Andreu D, Ubach J, Boman A, WÃ¥hlin B, Wade D, Merrifield RB, Boman HG. Shortened cecropin A-melittin hybrids. Significant size reduction retains potent antibiotic activity. Febs Letters. 296: 190-4. PMID 1733777 DOI: 10.1016/0014-5793(92)80377-S  0.454
1992 Wade D, Andreu D, Mitchell SA, Silveira AM, Boman A, Boman HG, Merrifield RB. Antibacterial peptides designed as analogs or hybrids of cecropins and melittin. International Journal of Peptide and Protein Research. 40: 429-36. PMID 1483838 DOI: 10.1111/J.1399-3011.1992.Tb00321.X  0.583
1991 Unson CG, Macdonald D, Ray K, Durrah TL, Merrifield RB. Position 9 replacement analogs of glucagon uncouple biological activity and receptor binding. The Journal of Biological Chemistry. 266: 2763-6. PMID 1847133  0.453
1990 Wade D, Boman A, WÃ¥hlin B, Drain CM, Andreu D, Boman HG, Merrifield RB. All-D amino acid-containing channel-forming antibiotic peptides. Proceedings of the National Academy of Sciences of the United States of America. 87: 4761-5. PMID 1693777 DOI: 10.1073/Pnas.87.12.4761  0.556
1989 Boman HC, Boman IA, Andreu D, Li ZQ, Merrifield RB, Schlenstedt G, Zimmermann R. Chemical synthesis and enzymic processing of precursor forms of cecropins A and B. The Journal of Biological Chemistry. 264: 5852-60. PMID 2925637  0.603
1989 Fink J, Boman A, Boman HG, Merrifield RB. Design, synthesis and antibacterial activity of cecropin-like model peptides. International Journal of Peptide and Protein Research. 33: 412-21. PMID 2777475 DOI: 10.1111/j.1399-3011.1989.tb00217.x  0.411
1989 Boman HG, Wade D, Boman IA, WÃ¥hlin B, Merrifield RB. Antibacterial and antimalarial properties of peptides that are cecropin-melittin hybrids. Febs Letters. 259: 103-6. PMID 2689223 DOI: 10.1016/0014-5793(89)81505-4  0.425
1989 Berg RH, Almdal K, Pedersen WB, Holm A, Tam JP, Merrifield RB. Long-chain polystyrene-grafted polyethylene film matrix: a new support for solid-phase peptide synthesis Journal of the American Chemical Society. 111: 8024-8026. DOI: 10.1021/Ja00202A059  0.306
1989 MERRIFIELD RB. ChemInform Abstract: Solid-Phase Peptide Synthesis After 25 Years: The Design and Synthesis of Antagonists of Glucagon Cheminform. 20. DOI: 10.1002/chin.198917355  0.416
1988 Li ZQ, Merrifield RB, Boman IA, Boman HG. Effects on electrophoretic mobility and antibacterial spectrum of removal of two residues from synthetic sarcotoxin IA and addition of the same residues to cecropin B. Febs Letters. 231: 299-302. PMID 3360136 DOI: 10.1016/0014-5793(88)80837-8  0.359
1988 Merrifield RB, Singer J, Chait BT. Mass spectrometric evaluation of synthetic peptides for deletions and insertions. Analytical Biochemistry. 174: 399-414. PMID 3239745 DOI: 10.1016/0003-2697(88)90039-5  0.45
1988 Steiner H, Andreu D, Merrifield RB. Binding and action of cecropin and cecropin analogues: antibacterial peptides from insects. Biochimica Et Biophysica Acta. 939: 260-6. PMID 3128324 DOI: 10.1016/0005-2736(88)90069-7  0.452
1988 Kofod H, Andreu D, Thams P, Merrifield RB, Hedeskov CJ, Hansen B, Lernmark A. Insulin release by glucagon and secretin: studies with secretin-glucagon hybrids. The American Journal of Physiology. 254: E454-8. PMID 2833112 DOI: 10.1152/Ajpendo.1988.254.4.E454  0.388
1988 Christensen B, Fink J, Merrifield RB, Mauzerall D. Channel-forming properties of cecropins and related model compounds incorporated into planar lipid membranes. Proceedings of the National Academy of Sciences of the United States of America. 85: 5072-6. PMID 2455891 DOI: 10.1073/pnas.85.14.5072  0.311
1988 Kaiser E, Tam JP, Kubiak TM, Merrifield RB. Chlorotrimethylsilane-phenol as a mild deprotection reagent for the tert-butyl based protecting groups in peptide synthesis Tetrahedron Letters. 29: 303-306. DOI: 10.1016/S0040-4039(00)80080-5  0.449
1988 Merrifield RB. Solid phase peptide synthesis after 25 years: The design and synthesis of antagonists of glucagon Makromolekulare Chemie. Macromolecular Symposia. 19: 31-67. DOI: 10.1002/masy.19880190104  0.415
1988 TAM JP, MERRIFIELD RB. ChemInform Abstract: Strong Acid Deprotection of Synthetic Peptides: Mechanisms and Methods Cheminform. 19. DOI: 10.1002/chin.198833350  0.447
1988 KAISER ES, TAM JP, KUBIAK TM, MERRIFIELD RB. ChemInform Abstract: Chlorotrimethylsilane - Phenol as a Mild Deprotection Reagent for the tert-Butyl Based Protecting Groups in Peptide Synthesis. Cheminform. 19. DOI: 10.1002/chin.198824348  0.452
1988 WANG SS, CHEN ST, WANG KT, MERRIFIELD RB. ChemInform Abstract: 4-Methoxybenzyloxycarbonyl Amino Acids in Solid Phase Peptide Synthesis. Cheminform. 19. DOI: 10.1002/chin.198816318  0.491
1987 Lu GS, Mojsov S, Merrifield RB. Synthesis and hormonal activity of [Tyr22] glucagon and [desHis1, Tyr22] glucagon. International Journal of Peptide and Protein Research. 29: 545-57. PMID 3454664 DOI: 10.1111/j.1399-3011.1987.tb02282.x  0.37
1987 Wang SS, Chen ST, Wang KT, Merrifield RB. 4-Methoxybenzyloxycarbonyl amino acids in solid phase peptide synthesis. International Journal of Peptide and Protein Research. 30: 662-7. PMID 3436702 DOI: 10.1111/j.1399-3011.1987.tb03377.x  0.448
1987 Unson CG, Andreu D, Gurzenda EM, Merrifield RB. Synthetic peptide antagonists of glucagon. Proceedings of the National Academy of Sciences of the United States of America. 84: 4083-7. PMID 3035568 DOI: 10.1073/pnas.84.12.4083  0.517
1987 Andreu D, Merrifield RB. Glucagon antagonists. Synthesis and inhibitory properties of Asp3-containing glucagon analogs. European Journal of Biochemistry / Febs. 164: 585-90. PMID 3032623 DOI: 10.1111/J.1432-1033.1987.Tb11167.X  0.508
1987 Trimble ER, Bruzzone R, Biden TJ, Meehan CJ, Andreu D, Merrifield RB. Secretin stimulates cyclic AMP and inositol trisphosphate production in rat pancreatic acinar tissue by two fully independent mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 84: 3146-50. PMID 2437575 DOI: 10.1073/pnas.84.10.3146  0.443
1987 HEATH WH, TAM JP, MERRIFIELD RB. ChemInform Abstract: Improved Deprotection of Cysteine-Containing Peptides in HF. Cheminform. 18. DOI: 10.1002/chin.198717332  0.416
1986 Merrifield RB. Solid phase synthesis Science. 232: 341-347. PMID 3961484 DOI: 10.1126/Science.3961484  0.357
1986 Heath WF, Merrifield RB. A synthetic approach to structure-function relationships in the murine epidermal growth factor molecule. Proceedings of the National Academy of Sciences of the United States of America. 83: 6367-71. PMID 3018729 DOI: 10.1073/pnas.83.17.6367  0.318
1986 Heath WF, Tam JP, Merrifield RB. Improved deprotection of cysteine-containing peptides in HF International Journal of Peptide and Protein Research. 28: 498-507. DOI: 10.1111/j.1399-3011.1986.tb03284.x  0.409
1986 Tam JP, Heath WF, Merrifield RB. Mechanisms for the removal of benzyl protecting groups in synthetic peptides by Trifluoromethanesulfonic Acid-Trifluoroacetic Acid-Dimethyl Sulfide Journal of the American Chemical Society. 108: 5242-5251. DOI: 10.1021/ja00277a031  0.426
1986 TAM JP, HEATH WF, MERRIFIELD RB. ChemInform Abstract: Mechanisms for the Removal of Benzyl Protecting Groups in Synthetic Peptides by Trifluoromethanesulfonic Acid - Trifluoroacetic Acid - Dimethyl Sulfide. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198652281  0.431
1985 Andreu D, Merrifield RB, Steiner H, Boman HG. N-terminal analogues of cecropin A: synthesis, antibacterial activity, and conformational properties. Biochemistry. 24: 1683-8. PMID 3924096 DOI: 10.1021/Bi00328A017  0.512
1985 van Hofsten P, Faye I, Kockum K, Lee JY, Xanthopoulos KG, Boman IA, Boman HG, Engström A, Andreu D, Merrifield RB. Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin B from Hyalophora cecropia. Proceedings of the National Academy of Sciences of the United States of America. 82: 2240-3. PMID 3857578 DOI: 10.1073/Pnas.82.8.2240  0.465
1985 Boman HG, Faye I, von Hofsten P, Kockum K, Lee JY, Xanthopoulos KG, Bennich H, Engström A, Merrifield RB, Andreu D. On the primary structures of lysozyme, cecropins and attacins from Hyalophora cecropia. Developmental and Comparative Immunology. 9: 551-8. PMID 3840100 DOI: 10.1016/0145-305X(85)90018-7  0.437
1985 Andreu D, Aschauer H, Kreil G, Merrifield RB. Solid-phase synthesis of PYLa and isolation of its natural counterpart, PGLa [PYLa-(4-24)] from skin secretion of Xenopus laevis. European Journal of Biochemistry / Febs. 149: 531-5. PMID 3839186 DOI: 10.1111/J.1432-1033.1985.Tb08957.X  0.654
1985 SARIN VK, KENT SBH, MITCHELL AR, MERRIFIELD RB. ChemInform Abstract: A GENERAL APPROACH TO THE QUANTITATION OF SYNTHETIC EFFICIENCY IN SOLID-PHASE PEPTIDE SYNTHESIS AS A FUNCTION OF CHAIN LENGTH Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198515334  0.397
1985 WHITNEY DB, TAM JP, MERRIFIELD RB. ChemInform Abstract: A NEW BASE-CATALYZED CLEAVAGE REACTION FOR THE PREPARATION OF PROTECTED PEPTIDES Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198512331  0.377
1984 Mojsov S, Merrifield RB. An improved synthesis of crystalline mammalian glucagon. European Journal of Biochemistry / Febs. 145: 601-5. PMID 6510418 DOI: 10.1111/j.1432-1033.1984.tb08599.x  0.356
1984 Sarin V, Kent SBH, Mitchell AR, Merrifield RB. GENERAL APPROACH TO THE QUANTITATION OF SYNTHETIC EFFICIENCY IN SOLID-PHASE PEPTIDE SYNTHESIS AS A FUNCTION OF CHAIN LENGTH Journal of the American Chemical Society. 106: 7845-7850. DOI: 10.1021/Ja00337A033  0.393
1984 Whitney DB, Tam JP, Merrifield RB. A new base-catalyzed cleavage reaction for the preparation of protected peptides Tetrahedron. 40: 4237-4244. DOI: 10.1016/S0040-4020(01)98798-8  0.374
1984 TAM JP, HEATH WF, MERRIFIELD RB. ChemInform Abstract: AN SN2 DEPROTECTION OF SYNTHETIC PEPTIDES WITH A LOW CONCENTRATION OF HYDROFLUORIC ACID IN DIMETHYL SULFIDE: EVIDENCE AND APPLICATION IN PEPTIDE SYNTHESIS Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198404306  0.474
1983 Kent SB, Merrifield RB. Chemical mechanism to account for artifactual formation of shortened peptides with free alpha-amino groups in solid phase peptide synthesis. International Journal of Peptide and Protein Research. 22: 57-65. PMID 6885250 DOI: 10.1111/J.1399-3011.1983.Tb02068.X  0.644
1983 Voss C, Dimarchi R, Whitney DB, Tjoeng FS, Merrifield RB, Tam JP. Synthesis of the protected tridecapeptide (56-68) of the VH domain of mouse myeloma immunoglobulin M603 and its reattachment to resin supports. International Journal of Peptide and Protein Research. 22: 204-13. PMID 6618764 DOI: 10.1111/J.1399-3011.1983.Tb02087.X  0.669
1983 Andreu D, Merrifield RB, Steiner H, Boman HG. Solid-phase synthesis of cecropin A and related peptides. Proceedings of the National Academy of Sciences of the United States of America. 80: 6475-9. PMID 6579533 DOI: 10.1073/Pnas.80.21.6475  0.623
1983 Tam JP, Heath WF, Merrifield RB. An SN2 deprotection of synthetic peptides with a low concentration of hydrofluoric acid in dimethyl sulfide: evidence and application in peptide synthesis Journal of the American Chemical Society. 105: 6442-6455. DOI: 10.1021/ja00359a014  0.469
1983 TAM JP, HEATH WF, MERRIFIELD RB. ChemInform Abstract: IMPROVED DEPROTECTION IN SOLID PHASE PEPTIDE SYNTHESIS: REMOVAL OF PROTECTING GROUPS FROM SYNTHETIC PEPTIDES BY AN SN2 MECHANISM WITH LOW CONCENTRATIONS OF HYDROGEN FLUORIDE IN DIMETHYL SULFIDE Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198308311  0.465
1983 Tam JP, Heath WF, Merrifield RB. SN2 deprotection of synthetic peptides with a low concentration of HF in dimethyl sulfide: Evidence and application in peptide synthesis Journal of the American Chemical Society. 105: 6442-6455.  0.435
1982 Dimarchi RD, Tam JP, Kent SB, Merrifield RB. Weak acid-catalyzed pyrrolidone carboxylic acid formation from glutamine during solid phase peptide synthesis. Minimization by rapid coupling. International Journal of Peptide and Protein Research. 19: 88-93. PMID 7118385 DOI: 10.1111/J.1399-3011.1982.Tb03027.X  0.68
1982 Merrifield RB, Vizioli LD, Boman HG. Synthesis of the antibacterial peptide cecropin A (1-33). Biochemistry. 21: 5020-31. PMID 6814482 DOI: 10.1021/bi00263a028  0.478
1982 Dimarchi RD, Tam JP, Merrifield RB. Solid phase synthesis of the protected 43-55 tridecapeptide of the heavy chain of myeloma immunoglobin M603, employing cyclohexyl ester protection for glutamic acid. International Journal of Peptide and Protein Research. 19: 270-9. PMID 6811468 DOI: 10.1111/j.1399-3011.1982.tb03038.x  0.652
1982 Heath WF, Tam JP, Merrifield RB. Improved deprotection in solid phase peptide synthesis: Deprotection of Ni-formyl-tryptophan to tryptophan in low concentrations of HF in Me2S-p-thiocresol mixtures Journal of the Chemical Society - Series Chemical Communications. 896-897. DOI: 10.1039/C39820000896  0.388
1982 Isied SS, Kuehn CG, Lyon JM, Merrifield RB. Specific peptide sequences for metal ion coordination. 1. Solid-phase synthesis of cyclo-(gly-his)3 Journal of the American Chemical Society. 104: 2632-2634. DOI: 10.1021/Ja00373A049  0.351
1982 Tam JP, Heath WF, Merrifield RB. Improved deprotection in solid phase peptide synthesis: quantitative reduction of methionine sulfoxide to methionine during HF cleavage Tetrahedron Letters. 23: 2939-2942. DOI: 10.1016/S0040-4039(00)87499-7  0.457
1982 Tam JP, Heath WF, Merrifield RB. Improved deprotection in solid phase reptide synthesis: removal of protecting groups from synthetic peptides by an SN2 mechanism with low concentrations of HF in dimethylsulfide Tetrahedron Letters. 23: 4435-4438. DOI: 10.1016/S0040-4039(00)85621-X  0.424
1982 TAM JP, HEATH WF, MERRIFIELD RB. ChemInform Abstract: IMPROVED DEPROTECTION IN SOLID PHASE PEPTIDE SYNTHESIS: QUANTITATIVE REDUCTION OF METHIONINE SULFOXIDE TO METHIONINE DURING HYDROGEN FLUORIDE CLEAVAGE Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198251346  0.426
1981 Wang SS, Tam JP, Wang BS, Merrifield RB. Enhancement of peptide coupling reactions by 4-dimethylaminopyridine. International Journal of Peptide and Protein Research. 18: 459-67. PMID 7341528 DOI: 10.1111/j.1399-3011.1981.tb03007.x  0.373
1981 Sarin VK, Kent SB, Tam JP, Merrifield RB. Quantitative monitoring of solid-phase peptide synthesis by the ninhydrin reaction. Analytical Biochemistry. 117: 147-57. PMID 7316187 DOI: 10.1016/0003-2697(81)90704-1  0.617
1981 Tam JP, DiMarchi RD, Merrifield RB. Design and synthesis of a multi-detachable benzhydrylamine-resin for solid phase peptide synthesis Tetrahedron Letters. 22: 2851-2854. DOI: 10.1016/S0040-4039(01)81767-6  0.641
1981 TAM JP, DIMARCHI RD, MERRIFIELD RB. ChemInform Abstract: DESIGN AND SYNTHESIS OF A MULTIDETACHABLE BENZHYDRYLAMINE RESIN FOR SOLID PHASE PEPTIDE SYNTHESIS Chemischer Informationsdienst. 12. DOI: 10.1002/chin.198150325  0.434
1981 BARANY G, MERRIFIELD RB. ChemInform Abstract: SOLID-PHASE PEPTIDE SYNTHESIS (CA. 1000 LITERATURANGABEN) Chemischer Informationsdienst. 12. DOI: 10.1002/chin.198103330  0.615
1980 Tam JP, Dimarchi RD, Merrifield RB. Photolabile multi-detachable p-alkoxybenzyl alcohol resin supports for peptide fragment or semi-synthesis. International Journal of Peptide and Protein Research. 16: 412-25. PMID 7216616 DOI: 10.1111/j.1399-3011.1980.tb02965.x  0.655
1980 Wong TW, Merrifield RB. Solid-phase synthesis of thymosin alpha 1 using tert-butyloxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin. Biochemistry. 19: 3233-8. PMID 7190831 DOI: 10.1021/bi00555a021  0.442
1980 Tam JP, Tjoeng FS, Merrifield RB. Design and synthesis of multidetachable resin supports for solid-phase peptide synthesis Journal of the American Chemical Society. 102: 6117-6127. DOI: 10.1021/ja00539a025  0.427
1980 Sarin VK, Kent SBH, Merrifield RB. Properties of swollen polymer networks. Solvation and swelling of peptide-containing resins in solid-phase peptide synthesis Journal of the American Chemical Society. 102: 5463-5470. DOI: 10.1021/Ja00537A006  0.453
1980 TAM JP, TJOENG FS, MERRIFIELD RB. ChemInform Abstract: DESIGN AND SYNTHESIS OF MULTIDETACHABLE RESIN SUPPORTS FOR SOLID-PHASE PEPTIDE SYNTHESIS Chemischer Informationsdienst. 11. DOI: 10.1002/chin.198051301  0.428
1980 Barany G, Merrifield RB. Kinetics and mechanism of the thiolytic removal of the dithiasuccinoyl (Dts) amino protecting group Journal of the American Chemical Society. 102: 3084-3095. DOI: 10.1002/Chin.198030106  0.516
1980 BARANY G, MERRIFIELD RB. ChemInform Abstract: KINETICS AND MECHANISM OF THE THIOLYTIC REMOVAL OF THE DITHIASUCCINOYL (DTS) AMINO PROTECTING GROUP Chemischer Informationsdienst. 11. DOI: 10.1002/chin.198030106  0.522
1980 TAM JP, KENT SBH, WONG TW, MERRIFIELD RB. ChemInform Abstract: IMPROVED SYNTHESIS OF 4-(BOC-AMINOACYLOXYMETHYL)PHENYLACETIC ACIDS FOR USE IN SOLID PHASE PEPTIDE SYNTHESIS Chemischer Informationsdienst. 11. DOI: 10.1002/chin.198012355  0.467
1980 TAM JP, WONG TW, RIEMEN MW, TJOENG FS, MERRIFIELD RB. ChemInform Abstract: CYCLOHEXYL ESTER AS A NEW PROTECTING GROUP FOR ASPARTYL PEPTIDES TO MINIMIZE ASPARTIMIDE FORMATION IN ACIDIC AND BASIC TREATMENTS Chemischer Informationsdienst. 11. DOI: 10.1002/chin.198004353  0.413
1979 Barany G, Merrifield RB. A chromatographic method for the quantitative analysis of the deprotection of dithiasuccinoyl (Dts) amino acids. Analytical Biochemistry. 95: 160-70. PMID 495950 DOI: 10.1016/0003-2697(79)90199-4  0.53
1979 Kent SB, Mitchell AR, Engelhard M, Merrifield RB. Mechanisms and prevention of trifluoroacetylation in solid-phase peptide synthesis. Proceedings of the National Academy of Sciences of the United States of America. 76: 2180-4. PMID 287055 DOI: 10.1073/Pnas.76.5.2180  0.658
1979 Simon EJ, Bonnet KA, Hiller JM, Rieman MW, Merrifield RB. Opioid activity of synthetic and naturally occurring enkephalin peptides. Biochemical Pharmacology. 28: 3333-7. PMID 230849 DOI: 10.1016/0006-2952(79)90129-1  0.382
1979 Tjoeng FS, Tam JP, Merrifield RB. Solid phase synthesis of the protected 27--42 hexadecapeptide of the heavy chain from myeloma immunoglobulin M603. Elimination of side reactions associated with glycyl-2-oxypropionyl-resin. International Journal of Peptide and Protein Research. 14: 262-74. PMID 42624 DOI: 10.1111/j.1399-3011.1979.tb01932.x  0.338
1979 Tam JP, Kent SBH, Wong TW, Merrifield RB. Improved synthesis of 4-(Boc-aminoacyloxymethyi)-phenylacetic acids for use in solid phase peptide synthesis Synthesis (Germany). 1979: 955-957. DOI: 10.1055/S-1979-28887  0.465
1979 Tam JP, Wong TW, Riemen MW, Tjoeng FS, Merrifield RB. Cyclohexyl ester as a new protecting group for aspartyl peptides to minimize aspartimide formation in acidic and basic treatments Tetrahedron Letters. 20: 4033-4036. DOI: 10.1016/S0040-4039(01)86496-0  0.409
1979 Krieger DE, Vidali G, Erickson BW, Allfrey VG, Merrifield RB. The synthesis of diacetylated histone H4-(1-37) for studies on the mechanism of histone deacetylation Bioorganic Chemistry. 8: 409-427. DOI: 10.1016/0045-2068(79)90044-0  0.571
1979 MERRIFIELD RB, BACH AE. ChemInform Abstract: 9-(2-SULFO)FLUORENYLMETHYLOXYCARBONYL CHLORIDE, A NEW REAGENT FOR THE PURIFICATION OF SYNTHETIC PEPTIDES Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197917356  0.427
1979 MITCHELL AR, KENT SBH, ENGELHARD M, MERRIFIELD RB. ChemInform Abstract: A NEW SYNTHETIC ROUTE TO TERT-BUTYLOXYCARBONYLAMINOACYL-4-(OXYMETHYL)PHENYLACETAMIDOMETHYL-RESIN, AN IMPROVED SUPPORT FOR SOLID-PHASE PEPTIDE SYNTHESIS Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197901315  0.434
1978 Merrifield RB, Bach AE. 9-(2-Sulfo)fluorenylmethyloxycarbonyl chloride, a new reagent for the purification of synthetic peptides Journal of Organic Chemistry. 43: 4808-4816. DOI: 10.1021/jo00419a021  0.425
1978 Mitchell AR, Kent SBH, Engelhard M, Merrifield RB. A new synthetic route to tert-butyloxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin, an improved support for solid-phase peptide synthesis Journal of Organic Chemistry. 43: 2845-2852. DOI: 10.1021/Jo00408A022  0.433
1978 Kent SBH, Mitchell AR, Barany G, Merrifield RB. Test for racemization in model peptide synthesis by direct chromatographic separation of diastereomers of the tetrapeptide leucylalanylglycylvaline Analytical Chemistry. 50: 155-159. DOI: 10.1021/Ac50023A035  0.628
1978 Kent SBH, Merrifield RB. Preparation and Properties oftert-Butyloxycarbonylaminoacyl-4-(oxymethyl) phenylacetamidomethyl-(Kel F-g-styrene) Resin, an Insoluble, Noncrosslinked Support for Solid Phase Peptide Synthesis Israel Journal of Chemistry. 17: 243-247. DOI: 10.1002/Ijch.197800043  0.362
1978 TAM JP, CUNNINGHAM-RUNDLES WF, ERICKSON BW, MERRIFIELD RB. ChemInform Abstract: SELECTIVE CLEAVAGE OF PROTECTED AMINO ACIDS AND PEPTIDES FROM OXYACYL RESINS BY AN 18-CROWN-6 COMPLEX OF POTASSIUM CYANIDE Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197805332  0.657
1977 Barany G, Merrifield RB. A new amino protecting group removable by reduction. Chemistry of the dithiasuccinoyl (Dts) function. Journal of the American Chemical Society. 99: 7363-5. PMID 915158 DOI: 10.1021/Ja00464A050  0.514
1977 Merrifield RB, Gisin BF, Bach AN. The limits of reaction of radioactive dicyclohexylcarbodiimide with amino groups during solid-phase peptide synthesis. The Journal of Organic Chemistry. 42: 1291-5. PMID 845712 DOI: 10.1021/jo00428a005  0.463
1977 Cosand WL, Merrifield RB. Concept of internal structural controls for evaluation of inactive synthetic peptide analogs: synthesis of [Orn13,14]apamin and its guanidination to an apamin derivative with full neurotoxic activity. Proceedings of the National Academy of Sciences of the United States of America. 74: 2771-5. PMID 268626 DOI: 10.1073/pnas.74.7.2771  0.387
1977 Tam JP, Cunningham-Rundles WF, Erickson BW, Merrifield RB. Selective cleavage of protected amino acids and peptides from oxyacyl resins by an 18-crown-6 complex of potassium cyanide Tetrahedron Letters. 18: 4001-4004. DOI: 10.1016/S0040-4039(01)83410-9  0.654
1977 MERRIFIELD RB, GISIN BF, BACH AN. ChemInform Abstract: THE LIMITS OF REACTION OF RADIOACTIVE DICYCLOHEXYLCARBODIIMIDE WITH AMINO GROUPS DURING SOLID-PHASE PEPTIDE SYNTHESIS Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197734365  0.465
1977 MITCHELL AR, ERICKSON BW, RYABTSEV MN, HODGES RS, MERRIFIELD RB. ChemInform Abstract: TERT-BUTOXYCARBONYLAMINOACYL-4-(OXYMETHYL)PHENYLACETAMIDOMETHYL-RESIN, A MORE ACID-RESISTANT SUPPORT FOR SOLID-PHASE PEPTIDE SYNTHESIS Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197706304  0.733
1977 MITCHELL AR, KENT SBH, ERICKSON BW, MERRIFIELD RB. ChemInform Abstract: PREPARATION OF AMINOMETHYL-POLYSTYRENE RESIN BY DIRECT AMIDOMETHYLATION Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197704331  0.487
1976 Yang CC, Merrifield RB. The beta-phenacyl ester as a temporary protecting group to minimize cyclic imide formation during subsequent treatment of aspartyl peptides with HF. The Journal of Organic Chemistry. 41: 1032-41. PMID 1255285 DOI: 10.1021/jo00868a025  0.322
1976 Krieger DE, Erickson BW, Merrifield RB. Affinity purification of synthetic peptides. Proceedings of the National Academy of Sciences of the United States of America. 73: 3160-4. PMID 1067609 DOI: 10.1073/pnas.73.9.3160  0.689
1976 Mitchell AR, Erickson BW, Ryabtsev MN, Hodges RS, Merrifield RB. Tert-butoxycarbonylaminoacyl-4-(oxymethyl)-phenylacetamidomethyl-resin, a more acid-resistant support for solid-phase peptide synthesis. Journal of the American Chemical Society. 98: 7357-62. PMID 10319 DOI: 10.1002/Chin.197706304  0.732
1976 Mitchell AR, Kent SBH, Erickson BW, Merrifield RB. Preparation of aminomethyl-polystyrene resin by direct amidomethylation Tetrahedron Letters. 17: 3795-3798. DOI: 10.1016/S0040-4039(00)93112-5  0.458
1976 YANG CC, MERRIFIELD RB. ChemInform Abstract: β-PHENACYL ESTER AS A TEMPORARY PROTECTING GROUP TO MINIMIZE CYCLIC IMIDE FORMATION DURING SUBSEQUENT TREATMENT OF ASPARTYL PEPTIDES WITH HYDROFLUORIC ACID Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/chin.197626327  0.377
1975 Feinberg RS, Merrifield RB. Modification of peptides containing glutamic acid by hydrogen fluoride-anisole mixtures. Gamma-acylation of anisole or the glutamyl nitrogen. Journal of the American Chemical Society. 97: 3485-96. PMID 1141578 DOI: 10.1021/ja00845a034  0.375
1975 Hodges RS, Merrifield RB. Monitoring of solid phase peptide synthesis by an automated spectrophotometric picrate method. Analytical Biochemistry. 65: 241-72. PMID 1130679 DOI: 10.1016/0003-2697(75)90509-6  0.613
1975 Hodges RS, Merrifield RB. The role of serine-123 in the activity and specificity of ribonuclease. Reactivation of ribonuclease 1-118 by the synthetic COOH-terminal tetradecapeptide, ribonuclease 111-124, and its O-methylserine and alanine analogs. The Journal of Biological Chemistry. 250: 1231-41. PMID 1112802  0.517
1975 Draper MW, Rizack MA, Merrifield RB. Synthetic position 5 analogs of adrenocorticotropin fragments and their in vitro lipolytic activity. Biochemistry. 14: 2933-8. PMID 167812 DOI: 10.1021/bi00684a022  0.453
1975 FEINBERG RS, MERRIFIELD RB. ChemInform Abstract: MODIFICATION OF PEPTIDES CONTAINING GLUTAMIC ACID BY HYDROGEN FLUORIDE-ANISOLE MIXTURES, GAMMA-ACYLATION OF ANISOLE OR THE GLUTAMYL NITROGEN Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/chin.197534367  0.379
1975 ERICKSON BW, MERRIFIELD RB. ChemInform Abstract: STABILITY OF SIDE-CHAIN PROTECTING GROUPS IN SOLID-PHASE PEPTIDE SYNTHESIS Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/chin.197509435  0.669
1974 Hodges RS, Merrifield RB. Synthesis of O-methyl-L-serine and Nalpha-tert-butyloxycarbonyl-O-methyl-L-serine. The Journal of Organic Chemistry. 39: 1870-2. PMID 4854587 DOI: 10.1002/Chin.197444404  0.383
1974 Merrifield RB, Mitchell AR, Clarke JE. Detection and prevention of urethane acylation during solid-phase peptide synthesis by anhydride methods. The Journal of Organic Chemistry. 39: 660-8. PMID 4833502 DOI: 10.1021/jo00919a018  0.429
1974 Hodges RS, Merrifield RB. Synthetic study of the effect of tyrosine at position 120 of ribonuclease. International Journal of Peptide and Protein Research. 6: 397-405. PMID 4455636 DOI: 10.1111/J.1399-3011.1974.Tb02401.X  0.456
1974 Feinberg R, Merrifield R. Zinc chloride-catalyzed chloromethylation of resins for solid phase peptide synthesis Tetrahedron. 30: 3209-3212. DOI: 10.1016/S0040-4020(01)97575-1  0.466
1974 Erickson BW, Merrifield RB. Stability of Side-Chain Protecting Groups in Solid-Phase Peptide Synthesis Israel Journal of Chemistry. 12: 79-85. DOI: 10.1002/ijch.197400009  0.667
1974 HODGES RS, MERRIFIELD RB. ChemInform Abstract: SYNTHESIS OF O-METHYL-L-SERINE AND N(ALPHA)-TERT-BUTYLOXYCARBONYL-O-METHYL-L-SERINE Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/chin.197444404  0.389
1974 MERRIFIELD RB, MITCHELL AR, CLARKE JE. ChemInform Abstract: DETECTION AND PREVENTION OF URETHANE ACYLATION DURING SOLID-PHASE PEPTIDE SYNTHESIS BY ANHYDRIDE METHODS Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/chin.197424383  0.434
1973 Erickson BW, Merrifield RB. Use of chlorinated benzyloxycarbonyl protecting groups to eliminate N -branching at lysine during solid-phase peptide synthesis. Journal of the American Chemical Society. 95: 3757-63. PMID 4708381 DOI: 10.1021/Ja00792A047  0.665
1973 Erickson BW, Merrifield RB. Acid stability of several benzylic protecting groups used in solid-phase peptide synthesis. Rearrangement of O-benzyltyrosine to 3-benzyltyrosine. Journal of the American Chemical Society. 95: 3750-6. PMID 4708380 DOI: 10.1002/Chin.197331419  0.667
1973 Hayashi R, Moore S, Merrifield RB. Preparation of pancreatic ribonucleases 1-114 and 1-115 and their reactivation by mixture and synthetic COOH-terminal peptides. The Journal of Biological Chemistry. 248: 3889-92. PMID 4575198  0.417
1973 Barany G, Merrifield RB. An ATP-Binding Peptide Cold Spring Harbor Symposia On Quantitative Biology. 37: 121-125. DOI: 10.1101/Sqb.1973.037.01.019  0.594
1973 ERICKSON BW, MERRIFIELD RB. ChemInform Abstract: USE OF CHLORINATED BENZYLOXYCARBONYL PROTECTING GROUPS TO ELIMINATE N(EPSILON)-BRANCHING AT LYSIN DURING SOLID-PHASE PEPTIDE SYNTHESIS Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197331420  0.666
1973 ERICKSON BW, MERRIFIELD RB. ChemInform Abstract: ACID STABILITY OF SEVERAL BENZYLIC PROTECTING GROUPS USED IN SOLID-PHASE PEPTIDE SYNTHESIS, REARRANGEMENT OF O-BENZYLTYROSINE TO 3-BENZYLTYROSINE Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/chin.197331419  0.669
1973 WANG S, MERRIFIELD RB. ChemInform Abstract: PEPTID-SYNTH. AN FESTER PHASE, DIE VERWENDUNG EINES TERT.-ALKOXYCARBONYLHYDRAZID- UND EINES TERT.-ALKYLALKOHOL-HARZES Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/chin.197311446  0.442
1972 Lin MC, Gutte B, Caldi DG, Moore S, Merrifield RB. Reactivation of des (119-124) ribonuclease A by mixture with synthetic COOH-terminal peptides; the role of phenylalanine-120. The Journal of Biological Chemistry. 247: 4768-74. PMID 5065952  0.432
1972 Gutte B, Lin MC, Caldi DG, Merrifield RB. Reactivation of des(119-, 120-, or 121-124) ribonuclease A by mixture with synthetic COOH-terminal peptides of varying lengths. The Journal of Biological Chemistry. 247: 4763-7. PMID 5065951  0.423
1972 Gisin BF, Merrifield RB. Synthesis of a hydrophobic potassium binding peptide. Journal of the American Chemical Society. 94: 6165-70. PMID 5054409 DOI: 10.1021/ja00772a039  0.419
1972 Gisin BF, Merrifield RB. Carboxyl-catalyzed intramolecular aminolysis. A side reaction in solid-phase peptide synthesis. Journal of the American Chemical Society. 94: 3102-6. PMID 5032495 DOI: 10.1021/ja00764a036  0.428
1972 GISIN BF, MERRIFIELD RB. ChemInform Abstract: SYNTH. EINES HYDROPHOBEN, KALIUM BINDENDEN PEPTIDS Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/chin.197245453  0.437
1972 GISIN BF, MERRIFIELD RB. ChemInform Abstract: CARBOXYL-KATALYSIERTE INTRAMOLEKULARE AMINOLYSE, NEBENRK. BEI DER FESTPHASEN-PEPTID-SYNTH. Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/chin.197230445  0.456
1970 Felix AM, Merrifield RB. Azide solid phase peptide synthesis. Journal of the American Chemical Society. 92: 1385-91. PMID 5414748 DOI: 10.1021/ja00708a046  0.463
1970 Marglin A, Merrifield RB. Chemical synthesis of peptides and proteins. Annual Review of Biochemistry. 39: 841-66. PMID 4920831 DOI: 10.1146/annurev.bi.39.070170.004205  0.411
1969 Wang SS, Merrifield RB. Preparation of some new biphenylisopropyloxycarbonyl amino acids and their application to the solid phase synthesis of a tryptophan-containing heptapeptide of bovine parathyroid hormone. International Journal of Protein Research. 1: 235-44. PMID 5408675 DOI: 10.1111/j.1399-3011.1969.tb01648.x  0.321
1969 Merrifield RB. The synthesis of biologically active peptides and proteins. Jama. 210: 1247-54. PMID 5394648 DOI: 10.1001/jama.1969.03160330047010  0.408
1969 Merrifield RB. Solid-phase peptide synthesis. Advances in Enzymology and Related Areas of Molecular Biology. 32: 221-96. PMID 4307033 DOI: 10.1002/9780470122778.ch6  0.461
1969 Wang S, Merrifield RB. Preparation of a tert-alkyloxycarbonylhydrazide resin and its application to solid phase peptide synthesis Journal of the American Chemical Society. 91: 6488-6491. DOI: 10.1021/ja01051a054  0.457
1967 Merrifield RB. New approaches to the chemical synthesis of peptides. Recent Progress in Hormone Research. 23: 451-82. PMID 4876483 DOI: 10.1016/b978-1-4831-9826-2.50013-1  0.388
1966 Merrifield RB, Stewart JM, Jernberg N. Instrument for automated synthesis of peptides. Analytical Chemistry. 38: 1905-14. PMID 5977852 DOI: 10.1021/ac50155a057  0.445
1966 Najjar VA, Merrifield RB. Solid Phase Peptide Synthesis. VI. The Use of the o-Nitrophenylsulfenyl Group in the Synthesis of the Octadecapeptide Bradykininylbradykinin* Biochemistry. 5: 3765-3770. DOI: 10.1021/bi00876a005  0.409
1965 MERRIFIELD RB. SOLID-PHASE PEPTIDE SYNTHESES. Endeavour. 24: 3-7. PMID 14263268  0.447
1965 Merrifield RB, Stewart JM. Automated peptide synthesis. Nature. 207: 522-3. PMID 5886140  0.458
1965 Merrifield RB. Automated synthesis of peptides. Science (New York, N.Y.). 150: 178-85. PMID 5319951 DOI: 10.1126/science.150.3693.178  0.458
1965 Marshall GR, Merrifield RB. Synthesis of Angiotensins by the Solid-Phase Method* Biochemistry. 4: 2394-2401. DOI: 10.1021/Bi00887A020  0.476
1964 MERRIFIELD RB. SOLID-PHASE PEPTIDE SYNTHESIS. 3. AN IMPROVED SYNTHESIS OF BRADYKININ. Biochemistry. 3: 1385-90. PMID 14229685 DOI: 10.1021/bi00897a032  0.446
1964 Merrifield RB. Solid Phase Peptide Synthesis. IV. The Synthesis of Methionyl-lysyl-bradykinin1 The Journal of Organic Chemistry. 29: 3100-3102. DOI: 10.1021/jo01033a526  0.453
1964 Merrifield RB. Solid Phase Peptide Synthesis. II. The Synthesis of Bradykinin Journal of the American Chemical Society. 86: 304-305. DOI: 10.1021/ja01056a056  0.424
1963 WOOLLEY DW, MERRIFIELD RB. Anomalies of the structural specificity of peptides. Annals of the New York Academy of Sciences. 104: 161-71. PMID 14001849 DOI: 10.1111/j.1749-6632.1963.tb17661.x  0.627
1963 Merrifield RB. Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide Journal of the American Chemical Society. 85: 2149-2154. DOI: 10.1021/ja00897a025  0.455
1958 WOOLLEY DW, MERRIFIELD RB. Specificity of peptides; new aspects of the specificity of peptides with vitamin and hormone action are described. Science (New York, N.Y.). 128: 238-40. PMID 13568768 DOI: 10.1126/science.128.3318.238  0.637
1958 MERRIFIELD RB. Competitive inhibition of a strepogenin-active peptide by related peptides. The Journal of Biological Chemistry. 232: 43-54. PMID 13549395  0.425
1958 Merrifield RB, Woolley DW. The Synthesis of Peptides with Strepogenin Activity1 Journal of the American Chemical Society. 80: 6635-6639. DOI: 10.1021/ja01557a046  0.664
1956 Merrifield RB, Woolley DW. The Synthesis of L-Seryl-L-histidyl-L-leucyl-L-valyl- L-glutamic Acid, a Peptide with Strepogenin Activity Journal of the American Chemical Society. 78: 4646-4649. DOI: 10.1021/ja01599a032  0.504
1956 Merrifield RB, Woolley DW. The Isolation and Determination of Structure of Peptides with Strepogenin Activity. I. Serylhistidylleucylvalylglutamic Acid and Serylhistidylleucylvalylglutamylalanylleucine from Insulin Journal of the American Chemical Society. 78: 358-362. DOI: 10.1021/ja01583a030  0.604
1955 MERRIFIELD RB, WOOLLEY DW. Isolation and determination of structure of a peptide with strepogenin activity. Archives of Biochemistry and Biophysics. 56: 265-6. PMID 14377574 DOI: 10.1016/0003-9861(55)90357-X  0.616
1955 WOOLLEY DW, MERRIFIELD RB, RESSLER C, DU VIGNEAUD V. Strepogenin activity of synthetic peptides related to oxytocin. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 89: 669-73. PMID 13254861 DOI: 10.3181/00379727-89-21911  0.638
1954 Woolley DW, Merrifield RB. HIGH STREPOGENIN POTENCY OF SYNTHETIC OXYTOCIN AND OF PURIFIED VASOPRESSIN Journal of the American Chemical Society. 76: 316-316. DOI: 10.1021/ja01630a112  0.491
1952 MERRIFIELD RB, WOOLLEY DW. The structure and microbiological activity of some dinucleotides isolated from yeast ribonucleic acid. The Journal of Biological Chemistry. 197: 521-37. PMID 12981083  0.482
1950 MERRIFIELD RB, DUNN MS. The microbiological determination of pyrimidines with lactobacilli. The Journal of Biological Chemistry. 186: 331-41. PMID 14778836  0.457
1949 DUNN MS, McCLURE LE, MERRIFIELD RB. The determination of proline in protein hydrolysates with Lactobacillus brevis. The Journal of Biological Chemistry. 179: 11-8. PMID 18119214  0.45
1948 MERRIFIELD RB, DUNN MS. Microbiological determination of cytosine, uracil and thymine. Archives of Biochemistry. 16: 339-41. PMID 18903702  0.447
Show low-probability matches.