Jianxiong Jiang, Ph.D. - Publications

Affiliations: 
2004-2008 Biological Sciences Auburn University, Auburn, AL, United States 
 2008-2014 Pharmacology Emory University School of Medicine, Atlanta, GA, United States 
 2015-2018 College of Pharmacy University of Cincinnati, Cincinnati, OH 
 2018- College of Pharmacy University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Neuropharmacology, Epilepsy, Glioma
Website:
https://academic.uthsc.edu/faculty/JianxiongJiang.html

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yu Y, Nguyen DT, Jiang J. G protein-coupled receptors in acquired epilepsy: Druggability and translatability. Progress in Neurobiology. 101682. PMID 31454545 DOI: 10.1016/j.pneurobio.2019.101682  0.56
2019 Dawn A, Yao X, Yu Y, Jiang J, Kumari H. Assessment of the toxicity of calixarenes and a metal-seamed calixarene: a chemical pathway for clinical application. Supramolecular Chemistry. 31: 425-431. PMID 31371909 DOI: 10.1080/10610278.2019.1616732  0.56
2019 Jiang J, Yu Y, Kinjo E, Du Y, Nguyen H, Dingledine R. Suppressing pro-inflammatory prostaglandin signaling attenuates excitotoxicity-associated neuronal inflammation and injury. Neuropharmacology. PMID 30763657 DOI: 10.1016/j.neuropharm.2019.02.011  1
2019 Qiu J, Li Q, Bell KA, Yao X, Du Y, Zhang E, Yu JJ, Yu Y, Shi Z, Jiang J. Small-molecule inhibition of prostaglandin E receptor 2 impairs cyclooxygenase-associated malignant glioma growth. British Journal of Pharmacology. PMID 30761522 DOI: 10.1111/bph.14622  0.8
2018 Jiang J, Van TM, Ganesh T, Dingledine R. Discovery of 2-Piperidinyl Phenyl Benzamides and Trisubstituted Pyrimidines as Positive Allosteric Modulators of the Prostaglandin Receptor EP2. Acs Chemical Neuroscience. PMID 29292987 DOI: 10.1021/acschemneuro.7b00486  1
2017 Hartings JA, York J, Carroll CP, Hinzman JM, Mahoney E, Krueger B, Winkler MKL, Major S, Horst V, Jahnke P, Woitzik J, Kola V, Du Y, Hagen M, Jiang J, et al. Subarachnoid blood acutely induces spreading depolarizations and early cortical infarction. Brain : a Journal of Neurology. 140: 2673-2690. PMID 28969382 DOI: 10.1093/brain/awx214  0.8
2017 Kang X, Qiu J, Li Q, Bell KA, Du Y, Jung DW, Lee JY, Hao J, Jiang J. Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype. Scientific Reports. 7: 9459. PMID 28842681 DOI: 10.1038/s41598-017-09528-z  0.8
2017 Jiang J, Qiu J, Li Q, Shi Z. Prostaglandin E2 Signaling: Alternative Target for Glioblastoma? Trends in Cancer. 3: 75-78. PMID 28718447 DOI: 10.1016/j.trecan.2016.12.002  0.36
2016 Qiu J, Shi Z, Jiang J. Cyclooxygenase-2 in glioblastoma multiforme. Drug Discovery Today. PMID 27693715 DOI: 10.1016/j.drudis.2016.09.017  0.36
2016 Dey A, Kang X, Qiu J, Du Y, Jiang J. Anti-Inflammatory Small Molecules To Treat Seizures and Epilepsy: From Bench to Bedside. Trends in Pharmacological Sciences. PMID 27062228 DOI: 10.1016/j.tips.2016.03.001  1
2015 Du Y, Kemper T, Qiu J, Jiang J. Defining the therapeutic time window for suppressing the inflammatory prostaglandin E2 signaling after status epilepticus. Expert Review of Neurotherapeutics. PMID 26689339 DOI: 10.1586/14737175.2016.1134322  1
2015 Du Y, Seibenhener ML, Yan J, Jiang J, Wooten MC. aPKC phosphorylation of HDAC6 results in increased deacetylation activity. Plos One. 10: e0123191. PMID 25860570 DOI: 10.1371/journal.pone.0123191  1
2015 Fu Y, Yang MS, Jiang J, Ganesh T, Joe E, Dingledine R. EP2 Receptor Signaling Regulates Microglia Death. Molecular Pharmacology. 88: 161-70. PMID 25715797 DOI: 10.1124/mol.115.098202  1
2015 Jiang J, Yang MS, Quan Y, Gueorguieva P, Ganesh T, Dingledine R. Therapeutic window for cyclooxygenase-2 related anti-inflammatory therapy after status epilepticus. Neurobiology of Disease. 76: 126-36. PMID 25600211 DOI: 10.1016/j.nbd.2014.12.032  1
2015 Varvel NH, Jiang J, Dingledine R. Candidate drug targets for prevention or modification of epilepsy. Annual Review of Pharmacology and Toxicology. 55: 229-47. PMID 25196047 DOI: 10.1146/annurev-pharmtox-010814-124607  1
2014 Ganesh T, Jiang J, Dingledine R. Development of second generation EP2 antagonists with high selectivity. European Journal of Medicinal Chemistry. 82: 521-35. PMID 24937185 DOI: 10.1016/j.ejmech.2014.05.076  1
2014 Ganesh T, Jiang J, Yang MS, Dingledine R. Lead optimization studies of cinnamic amide EP2 antagonists. Journal of Medicinal Chemistry. 57: 4173-84. PMID 24773616 DOI: 10.1021/jm5000672  1
2014 Rojas A, Jiang J, Ganesh T, Yang MS, Lelutiu N, Gueorguieva P, Dingledine R. Cyclooxygenase-2 in epilepsy. Epilepsia. 55: 17-25. PMID 24446952 DOI: 10.1111/epi.12461  1
2013 Yan J, Seibenhener ML, Calderilla-Barbosa L, Diaz-Meco MT, Moscat J, Jiang J, Wooten MW, Wooten MC. SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity. Plos One. 8: e76016. PMID 24086678 DOI: 10.1371/journal.pone.0076016  1
2013 Ganesh T, Jiang J, Shashidharamurthy R, Dingledine R. Discovery and characterization of carbamothioylacrylamides as EP2 selective antagonists. Acs Medicinal Chemistry Letters. 4: 616-621. PMID 23914286 DOI: 10.1021/ml400112h  1
2013 Jiang J, Dingledine R. Prostaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotection. Trends in Pharmacological Sciences. 34: 413-23. PMID 23796953 DOI: 10.1016/j.tips.2013.05.003  1
2013 Seibenhener ML, Zhao T, Du Y, Calderilla-Barbosa L, Yan J, Jiang J, Wooten MW, Wooten MC. Behavioral effects of SQSTM1/p62 overexpression in mice: support for a mitochondrial role in depression and anxiety. Behavioural Brain Research. 248: 94-103. PMID 23591541 DOI: 10.1016/j.bbr.2013.04.006  1
2013 Quan Y, Jiang J, Dingledine R. EP2 receptor signaling pathways regulate classical activation of microglia. The Journal of Biological Chemistry. 288: 9293-302. PMID 23404506 DOI: 10.1074/jbc.M113.455816  1
2013 Jiang J, Quan Y, Ganesh T, Pouliot WA, Dudek FE, Dingledine R. Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation. Proceedings of the National Academy of Sciences of the United States of America. 110: 3591-6. PMID 23401547 DOI: 10.1073/pnas.1218498110  1
2013 Jiang J, Dingledine R. Role of prostaglandin receptor EP2 in the regulations of cancer cell proliferation, invasion, and inflammation. The Journal of Pharmacology and Experimental Therapeutics. 344: 360-7. PMID 23192657 DOI: 10.1124/jpet.112.200444  1
2012 Jiang J, Ganesh T, Du Y, Quan Y, Serrano G, Qui M, Speigel I, Rojas A, Lelutiu N, Dingledine R. Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2. Proceedings of the National Academy of Sciences of the United States of America. 109: 3149-54. PMID 22323596 DOI: 10.1073/pnas.1120195109  1
2010 Jiang J, Ganesh T, Du Y, Thepchatri P, Rojas A, Lewis I, Kurtkaya S, Li L, Qui M, Serrano G, Shaw R, Sun A, Dingledine R. Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor. Proceedings of the National Academy of Sciences of the United States of America. 107: 2307-12. PMID 20080612 DOI: 10.1073/pnas.0909310107  1
2009 Jiang J, Parameshwaran K, Seibenhener ML, Kang MG, Suppiramaniam V, Huganir RL, Diaz-Meco MT, Wooten MW. AMPA receptor trafficking and synaptic plasticity require SQSTM1/p62. Hippocampus. 19: 392-406. PMID 19004011 DOI: 10.1002/hipo.20528  1
2008 Jadhav T, Geetha T, Jiang J, Wooten MW. Identification of a consensus site for TRAF6/p62 polyubiquitination. Biochemical and Biophysical Research Communications. 371: 521-4. PMID 18457658 DOI: 10.1016/j.bbrc.2008.04.138  1
2006 Jiang J, Suppiramaniam V, Wooten MW. Posttranslational modifications and receptor-associated proteins in AMPA receptor trafficking and synaptic plasticity. Neuro-Signals. 15: 266-82. PMID 17622793 DOI: 10.1159/000105517  1
2005 Geetha T, Jiang J, Wooten MW. Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling. Molecular Cell. 20: 301-12. PMID 16246731 DOI: 10.1016/j.molcel.2005.09.014  1
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