Yong Chen - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Neurodegeneration and Drug Abuse

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 White RS, Bhattacharya AK, Chen Y, Byrd M, McMullen MF, Siegel SJ, Carlson GC, Kim SF. Lysosomal iron modulates NMDA receptor-mediated excitation via small GTPase, Dexras1. Molecular Brain. 9: 38. PMID 27080392 DOI: 10.1186/S13041-016-0220-8  0.596
2016 Carlson GC, Lin RE, Chen Y, Brookshire BR, White RS, Lucki I, Siegel SJ, Kim SF. Dexras1 a unique ras-GTPase interacts with NMDA receptor activity and provides a novel dissociation between anxiety, working memory and sensory gating. Neuroscience. PMID 26946266 DOI: 10.1016/j.neuroscience.2016.02.063  0.607
2016 Chen Y, Bang S, McMullen MF, Kazi H, Talbot K, Ho MX, Carlson G, Arnold SE, Ong WY, Kim SF. Neuronal Activity-Induced Sterol Regulatory Element Binding Protein-1 (SREBP1) is Disrupted in Dysbindin-Null Mice-Potential Link to Cognitive Impairment in Schizophrenia. Molecular Neurobiology. PMID 26873854 DOI: 10.1007/S12035-016-9773-X  0.665
2015 Chen Y, Mathias L, Falero Perez JM, Kim SF. PKA-mediated phosphorylation of Dexras1 suppresses iron trafficking by inhibiting S-nitrosylation. Febs Letters. PMID 26358293 DOI: 10.1016/J.Febslet.2015.08.041  0.605
2015 Chen Y, Bang S, Park S, Shi H, Kim SF. Acyl-CoA-binding domain containing 3 modulates NAD+ metabolism through activating poly(ADP-ribose) polymerase 1. The Biochemical Journal. 469: 189-98. PMID 25940138 DOI: 10.1042/Bj20141487  0.613
2015 Jochems J, Teegarden SL, Chen Y, Boulden J, Challis C, Ben-Dor GA, Kim SF, Berton O. Enhancement of stress resilience through histone deacetylase 6-mediated regulation of glucocorticoid receptor chaperone dynamics. Biological Psychiatry. 77: 345-55. PMID 25442004 DOI: 10.1016/J.Biopsych.2014.07.036  0.583
2014 Bang S, Chen Y, Ahima RS, Kim SF. Convergence of IPMK and LKB1-AMPK signaling pathways on metformin action. Molecular Endocrinology (Baltimore, Md.). 28: 1186-93. PMID 24877601 DOI: 10.1210/Me.2014-1134  0.693
2014 Arnold SE, Lucki I, Brookshire BR, Carlson GC, Browne CA, Kazi H, Bang S, Choi BR, Chen Y, McMullen MF, Kim SF. High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice. Neurobiology of Disease. 67: 79-87. PMID 24686304 DOI: 10.1016/J.Nbd.2014.03.011  0.652
2013 Choi BR, Bang S, Chen Y, Cheah JH, Kim SF. PKA modulates iron trafficking in the striatum via small GTPase, Rhes. Neuroscience. 253: 214-20. PMID 23999124 DOI: 10.1016/j.neuroscience.2013.08.043  0.693
2013 Chen Y, Khan RS, Cwanger A, Song Y, Steenstra C, Bang S, Cheah JH, Dunaief J, Shindler KS, Snyder SH, Kim SF. Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3582-7. PMID 23426685 DOI: 10.1523/Jneurosci.1497-12.2013  0.695
2012 Chen Y, Patel V, Bang S, Cohen N, Millar J, Kim SF. Maturation and activity of sterol regulatory element binding protein 1 is inhibited by acyl-CoA binding domain containing 3. Plos One. 7: e49906. PMID 23166793 DOI: 10.1371/Journal.Pone.0049906  0.686
2012 Bang S, Kim S, Dailey MJ, Chen Y, Moran TH, Snyder SH, Kim SF. AMP-activated protein kinase is physiologically regulated by inositol polyphosphate multikinase. Proceedings of the National Academy of Sciences of the United States of America. 109: 616-20. PMID 22203993 DOI: 10.1073/Pnas.1119751109  0.702
2009 Chen Y, Liu-Chen LY. Chaperone-like effects of cell-permeant ligands on opioid receptors. Frontiers in Bioscience (Landmark Edition). 14: 634-43. PMID 19273091 DOI: 10.2741/3269  0.609
2009 Chen Y, Chen C, Kotsikorou E, Lynch DL, Reggio PH, Liu-Chen LY. GEC1-kappa opioid receptor binding involves hydrophobic interactions: GEC1 has chaperone-like effect. The Journal of Biological Chemistry. 284: 1673-85. PMID 19001416 DOI: 10.1074/jbc.M808303200  0.605
2008 Wang Y, Chen Y, Xu W, Lee DY, Ma Z, Rawls SM, Cowan A, Liu-Chen LY. 2-Methoxymethyl-salvinorin B is a potent kappa opioid receptor agonist with longer lasting action in vivo than salvinorin A. The Journal of Pharmacology and Experimental Therapeutics. 324: 1073-83. PMID 18089845 DOI: 10.1124/Jpet.107.132142  0.565
2007 Chen Y, Chen C, Liu-Chen LY. Dynorphin peptides differentially regulate the human kappa opioid receptor. Life Sciences. 80: 1439-48. PMID 17316701 DOI: 10.1016/j.lfs.2007.01.018  0.593
2006 Chen Y, Chen C, Wang Y, Liu-Chen LY. Ligands regulate cell surface level of the human kappa opioid receptor by activation-induced down-regulation and pharmacological chaperone-mediated enhancement: differential effects of nonpeptide and peptide agonists. The Journal of Pharmacology and Experimental Therapeutics. 319: 765-75. PMID 16882876 DOI: 10.1124/jpet.106.107987  0.615
2006 Wang Y, Dun SL, Huang P, Chen C, Chen Y, Unterwald EM, Dun NJ, Van Bockstaele EJ, Liu-Chen LY. Distribution and ultrastructural localization of GEC1 in the rat CNS. Neuroscience. 140: 1265-76. PMID 16650615 DOI: 10.1016/J.Neuroscience.2006.03.013  0.563
2006 Chen C, Li JG, Chen Y, Huang P, Wang Y, Liu-Chen LY. GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor. The Journal of Biological Chemistry. 281: 7983-93. PMID 16431922 DOI: 10.1074/jbc.M509805200  0.607
2005 Lee DY, Ma Z, Liu-Chen LY, Wang Y, Chen Y, Carlezon WA, Cohen B. New neoclerodane diterpenoids isolated from the leaves of Salvia divinorum and their binding affinities for human kappa opioid receptors. Bioorganic & Medicinal Chemistry. 13: 5635-9. PMID 16084728 DOI: 10.1016/J.Bmc.2005.05.054  0.554
2005 Lee DY, He M, Kondaveti L, Liu-Chen LY, Ma Z, Wang Y, Chen Y, Li JG, Beguin C, Carlezon WA, Cohen B. Synthesis and in vitro pharmacological studies of C(4) modified salvinorin A analogues. Bioorganic & Medicinal Chemistry Letters. 15: 4169-73. PMID 16051487 DOI: 10.1016/j.bmcl.2005.06.092  0.546
2005 Lee DY, Karnati VV, He M, Liu-Chen LY, Kondaveti L, Ma Z, Wang Y, Chen Y, Beguin C, Carlezon WA, Cohen B. Synthesis and in vitro pharmacological studies of new C(2) modified salvinorin A analogues. Bioorganic & Medicinal Chemistry Letters. 15: 3744-7. PMID 15993589 DOI: 10.1016/J.Bmcl.2005.05.048  0.583
2005 Béguin C, Richards MR, Wang Y, Chen Y, Liu-Chen LY, Ma Z, Lee DY, Carlezon WA, Cohen BM. Synthesis and in vitro pharmacological evaluation of salvinorin A analogues modified at C(2). Bioorganic & Medicinal Chemistry Letters. 15: 2761-5. PMID 15869877 DOI: 10.1016/J.Bmcl.2005.03.113  0.584
2004 Tang FR, Lee WL, Gao H, Chen Y, Loh YT, Chia SC. Expression of different isoforms of protein kinase C in the rat hippocampus after pilocarpine-induced status epilepticus with special reference to CA1 area and the dentate gyrus. Hippocampus. 14: 87-98. PMID 15058486 DOI: 10.1002/Hipo.10156  0.305
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