Samson T. Jacob - Publications

Affiliations: 
Ohio State University, Columbus, Columbus, OH 
Area:
Neuroscience Biology, Cell Biology, Molecular Biology

185 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Regan-Fendt K, Li D, Reyes R, Yu L, Wani NA, Hu P, Jacob ST, Ghoshal K, Payne PRO, Motiwala T. Transcriptomics-Based Drug Repurposing Approach Identifies Novel Drugs against Sorafenib-Resistant Hepatocellular Carcinoma. Cancers. 12. PMID 32977582 DOI: 10.3390/cancers12102730  0.8
2020 Teng KY, Barajas JM, Hu P, Jacob ST, Ghoshal K. Role of B Cell Lymphoma 2 in the Regulation of Liver Fibrosis in miR-122 Knockout Mice. Biology. 9. PMID 32650615 DOI: 10.3390/biology9070157  0.8
2019 Lin CH, Elkholy KH, Wani NA, Li D, Hu P, Barajas JM, Yu L, Zhang X, Jacob ST, Khan WN, Bai XF, Noonan AM, Ghoshal K. Ibrutinib potentiates anti-hepatocarcinogenic efficacy of sorafenib by targeting EGFR in tumor cells and BTK in immune cells in the stroma. Molecular Cancer Therapeutics. PMID 31582534 DOI: 10.1158/1535-7163.MCT-19-0135  0.8
2018 Majumder S, Ghoshal K, Datta J, Bai S, Dong X, Quan N, Plass C, Jacob ST. Role of DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma. The Journal of Biological Chemistry. 293: 12948. PMID 30120152 DOI: 10.1074/jbc.W118.004970  0.8
2018 Dong X, Ghoshal K, Majumder S, Yadav SP, Jacob ST. Mitochondrial transcription factor A and its downstream targets are up-regulated in a rat hepatoma. The Journal of Biological Chemistry. 293: 12947. PMID 30120151 DOI: 10.1074/jbc.W118.004969  0.8
2018 Majumder S, Varadharaj S, Ghoshal K, Monani U, Burghes AHM, Jacob ST. Identification of a novel cyclic AMP-response element (CRE-II) and the role of CREB-1 in the cAMP-induced expression of the survival motor neuron () gene. The Journal of Biological Chemistry. 293: 12946. PMID 30120150 DOI: 10.1074/jbc.W118.004968  0.8
2018 Nasser MW, Datta J, Nuovo G, Kutay H, Motiwala T, Majumder S, Wang B, Suster S, Jacob ST, Ghoshal K. Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. The Journal of Biological Chemistry. 293: 12945. PMID 30120149 DOI: 10.1074/jbc.W118.004967  0.8
2018 Barajas JM, Reyes R, Guerrero MJ, Jacob ST, Motiwala T, Ghoshal K. The role of miR-122 in the dysregulation of glucose-6-phosphate dehydrogenase (G6PD) expression in hepatocellular cancer. Scientific Reports. 8: 9105. PMID 29904144 DOI: 10.1038/s41598-018-27358-5  0.8
2018 Badawi M, Kim J, Dauki A, Sutaria D, Motiwala T, Reyes R, Wani N, Kolli S, Jiang J, Coss CC, Jacob ST, Phelps MA, Schmittgen TD. CD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128. Oncotarget. 9: 26032-26045. PMID 29899840 DOI: 10.18632/oncotarget.25430  0.4
2018 Ghoshal K, Datta J, Majumder S, Bai S, Kutay H, Motiwala T, Jacob ST. Correction for Ghoshal et al., "5-Aza-Deoxycytidine Induces Selective Degradation of DNA Methyltransferase 1 by a Proteasomal Pathway That Requires the KEN Box, Bromo-Adjacent Homology Domain, and Nuclear Localization Signal". Molecular and Cellular Biology. 38. PMID 29712769 DOI: 10.1128/MCB.00539-17  0.8
2018 Bai S, Ghoshal K, Jacob ST. Identification of T-cadherin as a novel target of DNA methyltransferase 3B and its role in the suppression of nerve growth factor-mediated neurite outgrowth in PC12 cells. The Journal of Biological Chemistry. 293: 3592. PMID 29523698 DOI: 10.1074/jbc.W118.002434  0.8
2018 Majumder S, Ghoshal K, Datta J, Smith DS, Bai S, Jacob ST. Role of DNA methyltransferases in regulation of human ribosomal RNA gene transcription. The Journal of Biological Chemistry. 293: 3591. PMID 29523697 DOI: 10.1074/jbc.W118.002433  0.8
2018 Bai S, Datta J, Jacob ST, Ghoshal K. Treatment of PC12 cells with nerve growth factor induces proteasomal degradation of T-cadherin that requires tyrosine phosphorylation of its cadherin domain. The Journal of Biological Chemistry. 293: 3590. PMID 29523696 DOI: 10.1074/jbc.W118.002432  0.8
2018 Motiwala T, Majumder S, Ghoshal K, Kutay H, Datta J, Roy S, Lucas DM, Jacob ST. PTPROt inactivates the oncogenic fusion protein BCR/ABL and suppresses transformation of K562 cells. The Journal of Biological Chemistry. 293: 3589. PMID 29523695 DOI: 10.1074/jbc.W118.002431  0.8
2018 Lu Y, Roy S, Nuovo G, Ramaswamy B, Miller T, Shapiro C, Jacob ST, Majumder S. Anti-microRNA-222 (anti-miR-222) and -181B suppresses growth of tamoxifen-resistant xenografts in mouse by targeting TIMP3 protein and modulating mitogenic signal. The Journal of Biological Chemistry. 293: 3588. PMID 29523694 DOI: 10.1074/jbc.W118.002430  0.44
2017 Wani N, Zhang B, Teng KY, Barajas J, Motiwala T, Hu P, Yu L, Brüschweiler R, Ghoshal K, Jacob ST. Reprograming of Glucose Metabolism by Zerumbone Suppresses Hepatocarcinogenesis. Molecular Cancer Research : McR. PMID 29187559 DOI: 10.1158/1541-7786.MCR-17-0304  0.8
2017 Huang W, Mehta D, Sif S, Kent LN, Jacob ST, Ghoshal K, Mehta KD. Dietary fat/cholesterol-sensitive PKCβ-RB signaling: Potential role in NASH/HCC axis. Oncotarget. 8: 73757-73765. PMID 29088742 DOI: 10.18632/oncotarget.17890  0.8
2017 Huang W, Mehta D, Sif S, Kent LN, Jacob ST, Ghoshal K, Mehta KD. Dietary fat/cholesterol-sensitive PKCβ-RB signaling: Potential role in NASH/HCC axis. Oncotarget. PMID 28575859 DOI: 10.18632/oncotarget.17890  0.8
2016 Teng KY, Han J, Zhang X, Hsu SH, He S, Wani N, Barajas J, Snyder LA, Frankel WL, Caligiuri MA, Jacob ST, Yu J, Ghoshal K. Blocking the Ccl2-Ccr2 axis using Ccl2 neutralizing antibody is an effective therapy for hepatocellular cancer in a mouse model. Molecular Cancer Therapeutics. PMID 27980102 DOI: 10.1158/1535-7163.MCT-16-0124  0.8
2016 Reyes R, Wani N A, Ghoshal K, Jacob S T, Motiwala T. Sorafenib and 2-Deoxyglucose Synergistically Inhibit Proliferation of both Sorafenib Sensitive and Resistant HCC Cells by Inhibiting ATP Production. Gene Expression. PMID 27938509 DOI: 10.3727/105221616X693855  0.8
2015 Motiwala T, Kutay H, Zanesi N, Frissora FW, Mo X, Muthusamy N, Jacob ST. PTPROt-mediated regulation of p53/Foxm1 suppresses leukemic phenotype in a CLL mouse model. Leukemia. 29: 1350-9. PMID 25482129 DOI: 10.1038/leu.2014.341  0.8
2015 Wang X, He H, Lu Y, Ren W, Teng KY, Chiang CL, Yang Z, Yu B, Hsu S, Jacob ST, Ghoshal K, Lee LJ. Indole-3-carbinol inhibits tumorigenicity of hepatocellular carcinoma cells via suppression of microRNA-21 and upregulation of phosphatase and tensin homolog. Biochimica Et Biophysica Acta. 1853: 244-53. PMID 25447674 DOI: 10.1016/j.bbamcr.2014.10.017  0.8
2014 Reyes RK, Motiwala T, Jacob ST. Regulation of glucose metabolism in hepatocarcinogenesis by microRNAs. Gene Expression. 16: 85-92. PMID 24801169 DOI: 10.3727/105221614X13919976902093  0.8
2014 Jacob ST, Reddy JK. Introduction. Special issue of Gene Expression. Gene Expression. 16: 49. PMID 24801165 DOI: 10.3727/105221614X13959522308830  0.8
2014 Wang B, Hsu SH, Wang X, Kutay H, Bid HK, Yu J, Ganju RK, Jacob ST, Yuneva M, Ghoshal K. Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2. Hepatology (Baltimore, Md.). 59: 555-66. PMID 24038073 DOI: 10.1002/hep.26712  0.8
2013 Wang X, Yu B, Ren W, Mo X, Zhou C, He H, Jia H, Wang L, Jacob ST, Lee RJ, Ghoshal K, Lee LJ. Enhanced hepatic delivery of siRNA and microRNA using oleic acid based lipid nanoparticle formulations. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 690-8. PMID 24121065 DOI: 10.1016/j.jconrel.2013.09.027  0.8
2013 Hsu SH, Yu B, Wang X, Lu Y, Schmidt CR, Lee RJ, Lee LJ, Jacob ST, Ghoshal K. Cationic lipid nanoparticles for therapeutic delivery of siRNA and miRNA to murine liver tumor. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 1169-80. PMID 23727126 DOI: 10.1016/j.nano.2013.05.007  0.8
2013 Gamage SA, Brooke DG, Redkar S, Datta J, Jacob ST, Denny WA. Structure-activity relationships for 4-anilinoquinoline derivatives as inhibitors of the DNA methyltransferase enzyme DNMT1. Bioorganic & Medicinal Chemistry. 21: 3147-53. PMID 23639684 DOI: 10.1016/j.bmc.2013.03.033  0.8
2013 Hsu SH, Motiwala T, Roy S, Claus R, Mustafa M, Plass C, Freitas MA, Ghoshal K, Jacob ST. Methylation of the PTPRO gene in human hepatocellular carcinoma and identification of VCP as its substrate. Journal of Cellular Biochemistry. 114: 1810-8. PMID 23533167 DOI: 10.1002/jcb.24525  0.8
2012 Nagaraja T, Chen L, Balasubramanian A, Groopman JE, Ghoshal K, Jacob ST, Leask A, Brigstock DR, Anand AR, Ganju RK. Activation of the connective tissue growth factor (CTGF)-transforming growth factor β 1 (TGF-β 1) axis in hepatitis C virus-expressing hepatocytes. Plos One. 7: e46526. PMID 23056332 DOI: 10.1371/journal.pone.0046526  0.8
2012 Datta J, Ghoshal K, Motiwala T, Jacob ST. Novel Insights into the Molecular Mechanism of Action of DNA Hypomethylating Agents: Role of Protein Kinase C δ in Decitabine-Induced Degradation of DNA Methyltransferase 1. Genes & Cancer. 3: 71-81. PMID 22893792 DOI: 10.1177/1947601912452665  0.8
2012 Hsu SH, Wang B, Kota J, Yu J, Costinean S, Kutay H, Yu L, Bai S, La Perle K, Chivukula RR, Mao H, Wei M, Clark KR, Mendell JR, Caligiuri MA, ... Jacob ST, et al. Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. The Journal of Clinical Investigation. 122: 2871-83. PMID 22820288 DOI: 10.1172/JCI63539  0.8
2012 Yu B, Hsu SH, Zhou C, Wang X, Terp MC, Wu Y, Teng L, Mao Y, Wang F, Xue W, Jacob ST, Ghoshal K, Lee RJ, Lee LJ. Lipid nanoparticles for hepatic delivery of small interfering RNA. Biomaterials. 33: 5924-34. PMID 22652024 DOI: 10.1016/j.biomaterials.2012.05.002  0.8
2012 Blum W, Schwind S, Tarighat SS, Geyer S, Eisfeld AK, Whitman S, Walker A, Klisovic R, Byrd JC, Santhanam R, Wang H, Curfman JP, Devine SM, Jacob S, Garr C, et al. Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia. Blood. 119: 6025-31. PMID 22566605 DOI: 10.1182/blood-2012-03-413898  0.8
2012 Wang B, Hsu SH, Frankel W, Ghoshal K, Jacob ST. Stat3-mediated activation of microRNA-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. Hepatology (Baltimore, Md.). 56: 186-97. PMID 22318941 DOI: 10.1002/hep.25632  0.8
2011 Majumder S, Jacob ST. Emerging role of microRNAs in drug-resistant breast cancer. Gene Expression. 15: 141-51. PMID 22268296 DOI: 10.3727/105221611X13176664479287  0.8
2011 Jacob ST. Breast cancer. Introduction. Gene Expression. 15: 103. PMID 22268292 DOI: 10.3727/105221611X13183417914801  0.8
2011 Lu Y, Roy S, Nuovo G, Ramaswamy B, Miller T, Shapiro C, Jacob ST, Majumder S. Anti-microRNA-222 (anti-miR-222) and -181B suppress growth of tamoxifen-resistant xenografts in mouse by targeting TIMP3 protein and modulating mitogenic signal. The Journal of Biological Chemistry. 286: 42292-302. PMID 22009755 DOI: 10.1074/jbc.M111.270926  0.8
2011 Motiwala T, Zanesi N, Datta J, Roy S, Kutay H, Checovich AM, Kaou M, Zhong Y, Johnson AJ, Lucas DM, Heerema NA, Hagan J, Mo X, Jarjoura D, Byrd JC, ... ... Jacob ST, et al. AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia. Blood. 118: 6132-40. PMID 22001392 DOI: 10.1182/blood-2011-01-323147  0.8
2011 Wang B, Jacob ST. Role of cancer stem cells in hepatocarcinogenesis. Genome Medicine. 3: 11. PMID 21345246 DOI: 10.1186/gm225  0.8
2010 Majumder S, Roy S, Kaffenberger T, Wang B, Costinean S, Frankel W, Bratasz A, Kuppusamy P, Hai T, Ghoshal K, Jacob ST. Loss of metallothionein predisposes mice to diethylnitrosamine-induced hepatocarcinogenesis by activating NF-kappaB target genes. Cancer Research. 70: 10265-76. PMID 21159647 DOI: 10.1158/0008-5472.CAN-10-2839  0.8
2010 Motiwala T, Datta J, Kutay H, Roy S, Jacob ST. Lyn kinase and ZAP70 are substrates of PTPROt in B-cells: Lyn inactivation by PTPROt sensitizes leukemia cells to VEGF-R inhibitor pazopanib. Journal of Cellular Biochemistry. 110: 846-56. PMID 20564182 DOI: 10.1002/jcb.22593  0.8
2010 Ghoshal K, Motiwala T, Claus R, Yan P, Kutay H, Datta J, Majumder S, Bai S, Majumder A, Huang T, Plass C, Jacob ST. HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors. Plos One. 5: e10338. PMID 20454457 DOI: 10.1371/journal.pone.0010338  0.8
2010 Wang B, Hsu SH, Majumder S, Kutay H, Huang W, Jacob ST, Ghoshal K. TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3. Oncogene. 29: 1787-97. PMID 20023698 DOI: 10.1038/onc.2009.468  0.8
2010 Majumder S, Alinari L, Roy S, Miller T, Datta J, Sif S, Baiocchi R, Jacob ST. Methylation of histone H3 and H4 by PRMT5 regulates ribosomal RNA gene transcription. Journal of Cellular Biochemistry. 109: 553-63. PMID 19998411 DOI: 10.1002/jcb.22432  0.8
2009 Wang B, Majumder S, Nuovo G, Kutay H, Volinia S, Patel T, Schmittgen TD, Croce C, Ghoshal K, Jacob ST. Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice. Hepatology (Baltimore, Md.). 50: 1152-61. PMID 19711427 DOI: 10.1002/hep.23100  0.8
2009 Datta J, Ghoshal K, Denny WA, Gamage SA, Brooke DG, Phiasivongsa P, Redkar S, Jacob ST. A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation. Cancer Research. 69: 4277-85. PMID 19417133 DOI: 10.1158/0008-5472.CAN-08-3669  0.8
2009 Ramaswamy B, Majumder S, Roy S, Ghoshal K, Kutay H, Datta J, Younes M, Shapiro CL, Motiwala T, Jacob ST. Estrogen-mediated suppression of the gene encoding protein tyrosine phosphatase PTPRO in human breast cancer: mechanism and role in tamoxifen sensitivity. Molecular Endocrinology (Baltimore, Md.). 23: 176-87. PMID 19095770 DOI: 10.1210/me.2008-0211  0.8
2009 Motiwala T, Majumder S, Ghoshal K, Kutay H, Datta J, Roy S, Lucas DM, Jacob ST. PTPROt inactivates the oncogenic fusion protein BCR/ABL and suppresses transformation of K562 cells. The Journal of Biological Chemistry. 284: 455-64. PMID 18997174 DOI: 10.1074/jbc.M802840200  0.8
2008 Nasser MW, Datta J, Nuovo G, Kutay H, Motiwala T, Majumder S, Wang B, Suster S, Jacob ST, Ghoshal K. Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. The Journal of Biological Chemistry. 283: 33394-405. PMID 18818206 DOI: 10.1074/jbc.M804788200  0.8
2008 Miller TE, Ghoshal K, Ramaswamy B, Roy S, Datta J, Shapiro CL, Jacob S, Majumder S. MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1. The Journal of Biological Chemistry. 283: 29897-903. PMID 18708351 DOI: 10.1074/jbc.M804612200  0.8
2008 Datta J, Kutay H, Nasser MW, Nuovo GJ, Wang B, Majumder S, Liu CG, Volinia S, Croce CM, Schmittgen TD, Ghoshal K, Jacob ST. Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Research. 68: 5049-58. PMID 18593903 DOI: 10.1158/0008-5472.CAN-07-6655  0.8
2007 Ren C, Liu S, Ghoshal K, Hsu PH, Jacob ST, Marcucci G, Freitas MA. Simultaneous metabolic labeling of cells with multiple amino acids: Localization and dynamics of histone acetylation and methylation. Proteomics. Clinical Applications. 1: 130-42. PMID 21136616 DOI: 10.1002/prca.200600631  0.8
2007 Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology. 133: 647-58. PMID 17681183 DOI: 10.1053/j.gastro.2007.05.022  0.8
2007 Bai S, Datta J, Jacob ST, Ghoshal K. Treatment of PC12 cells with nerve growth factor induces proteasomal degradation of T-cadherin that requires tyrosine phosphorylation of its cadherin domain. The Journal of Biological Chemistry. 282: 27171-80. PMID 17631504 DOI: 10.1074/jbc.M700691200  0.8
2007 Pal S, Baiocchi RA, Byrd JC, Grever MR, Jacob ST, Sif S. Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma. The Embo Journal. 26: 3558-69. PMID 17627275 DOI: 10.1038/sj.emboj.7601794  0.8
2007 Motiwala T, Majumder S, Kutay H, Smith DS, Neuberg DS, Lucas DM, Byrd JC, Grever M, Jacob ST. Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 3174-81. PMID 17545520 DOI: 10.1158/1078-0432.CCR-06-1720  0.8
2007 Datta J, Majumder S, Kutay H, Motiwala T, Frankel W, Costa R, Cha HC, MacDougald OA, Jacob ST, Ghoshal K. Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade. Cancer Research. 67: 2736-46. PMID 17363595 DOI: 10.1158/0008-5472.CAN-06-4433  0.8
2006 Kutay H, Bai S, Datta J, Motiwala T, Pogribny I, Frankel W, Jacob ST, Ghoshal K. Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. Journal of Cellular Biochemistry. 99: 671-8. PMID 16924677 DOI: 10.1002/jcb.20982  0.8
2006 Motiwala T, Jacob ST. Role of protein tyrosine phosphatases in cancer. Progress in Nucleic Acid Research and Molecular Biology. 81: 297-329. PMID 16891175 DOI: 10.1016/S0079-6603(06)81008-1  0.8
2006 Majumder S, Ghoshal K, Datta J, Smith DS, Bai S, Jacob ST. Role of DNA methyltransferases in regulation of human ribosomal RNA gene transcription. The Journal of Biological Chemistry. 281: 22062-72. PMID 16735507 DOI: 10.1074/jbc.M601155200  0.8
2006 Ghoshal K, Li X, Datta J, Bai S, Pogribny I, Pogribny M, Huang Y, Young D, Jacob ST. A folate- and methyl-deficient diet alters the expression of DNA methyltransferases and methyl CpG binding proteins involved in epigenetic gene silencing in livers of F344 rats. The Journal of Nutrition. 136: 1522-7. PMID 16702315  0.8
2006 Bai S, Ghoshal K, Jacob ST. Identification of T-cadherin as a novel target of DNA methyltransferase 3B and its role in the suppression of nerve growth factor-mediated neurite outgrowth in PC12 cells. The Journal of Biological Chemistry. 281: 13604-11. PMID 16537533 DOI: 10.1074/jbc.M513278200  0.8
2006 Majumder S, Kutay H, Datta J, Summers D, Jacob ST, Ghoshal K. Epigenetic regulation of metallothionein-i gene expression: differential regulation of methylated and unmethylated promoters by DNA methyltransferases and methyl CpG binding proteins. Journal of Cellular Biochemistry. 97: 1300-16. PMID 16329111 DOI: 10.1002/jcb.20738  0.8
2005 Datta J, Majumder S, Bai S, Ghoshal K, Kutay H, Smith DS, Crabb JW, Jacob ST. Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells. Cancer Research. 65: 10891-900. PMID 16322236 DOI: 10.1158/0008-5472.CAN-05-1455  0.8
2005 Ren C, Zhang L, Freitas MA, Ghoshal K, Parthun MR, Jacob ST. Peptide mass mapping of acetylated isoforms of histone H4 from mouse lymphosarcoma cells treated with histone deacetylase (HDACs) inhibitors. Journal of the American Society For Mass Spectrometry. 16: 1641-53. PMID 16099169 DOI: 10.1016/j.jasms.2005.06.001  0.8
2005 Ghoshal K, Datta J, Majumder S, Bai S, Kutay H, Motiwala T, Jacob ST. 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal. Molecular and Cellular Biology. 25: 4727-41. PMID 15899874 DOI: 10.1128/MCB.25.11.4727-4741.2005  0.8
2005 Jacob ST, Motiwala T. Epigenetic regulation of protein tyrosine phosphatases: potential molecular targets for cancer therapy. Cancer Gene Therapy. 12: 665-72. PMID 15803146 DOI: 10.1038/sj.cgt.7700828  0.8
2005 Bai S, Ghoshal K, Datta J, Majumder S, Yoon SO, Jacob ST. DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2. Molecular and Cellular Biology. 25: 751-66. PMID 15632075 DOI: 10.1128/MCB.25.2.751-766.2005  0.8
2004 Motiwala T, Kutay H, Ghoshal K, Bai S, Seimiya H, Tsuruo T, Suster S, Morrison C, Jacob ST. Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 101: 13844-9. PMID 15356345 DOI: 10.1073/pnas.0405451101  0.8
2004 Majumder S, Varadharaj S, Ghoshal K, Monani U, Burghes AH, Jacob ST. Identification of a novel cyclic AMP-response element (CRE-II) and the role of CREB-1 in the cAMP-induced expression of the survival motor neuron (SMN) gene. The Journal of Biological Chemistry. 279: 14803-11. PMID 14742439 DOI: 10.1074/jbc.M308225200  0.8
2004 Ghoshal K, Majumder S, Datta J, Motiwala T, Bai S, Sharma SM, Frankel W, Jacob ST. Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression. The Journal of Biological Chemistry. 279: 6783-93. PMID 14610093 DOI: 10.1074/jbc.M309393200  0.8
2003 Motiwala T, Ghoshal K, Das A, Majumder S, Weichenhan D, Wu YZ, Holman K, James SJ, Jacob ST, Plass C. Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas. Oncogene. 22: 6319-31. PMID 14508512 DOI: 10.1038/sj.onc.1206750  0.8
2003 Majumder S, Ghoshal K, Summers D, Bai S, Datta J, Jacob ST. Chromium(VI) down-regulates heavy metal-induced metallothionein gene transcription by modifying transactivation potential of the key transcription factor, metal-responsive transcription factor 1. The Journal of Biological Chemistry. 278: 26216-26. PMID 12716893 DOI: 10.1074/jbc.M302887200  0.8
2003 Datta J, Ghoshal K, Sharma SM, Tajima S, Jacob ST. Biochemical fractionation reveals association of DNA methyltransferase (Dnmt) 3b with Dnmt1 and that of Dnmt 3a with a histone H3 methyltransferase and Hdac1 Journal of Cellular Biochemistry. 88: 855-864. PMID 12616525 DOI: 10.1002/jcb.10457  0.8
2002 Jacob ST, Majumder S, Ghoshal K. Suppression of metallothionein-I/II expression and its probable molecular mechanisms. Environmental Health Perspectives. 110: 827-30. PMID 12426140  0.8
2002 Ghoshal K, Datta J, Majumder S, Bai S, Dong X, Parthun M, Jacob ST. Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure. Molecular and Cellular Biology. 22: 8302-19. PMID 12417732 DOI: 10.1128/MCB.22.23.8302-8319.2002  0.8
2002 Dong X, Ghoshal K, Majumder S, Yadav SP, Jacob ST. Mitochondrial transcription factor A and its downstream targets are up-regulated in a rat hepatoma. The Journal of Biological Chemistry. 277: 43309-18. PMID 12198131 DOI: 10.1074/jbc.M206958200  0.8
2002 Ghoshal K, Majumder S, Jacob ST. Analysis of promoter methylation and its role in silencing metallothionein I gene expression in tumor cells. Methods in Enzymology. 353: 476-86. PMID 12078520 DOI: 10.1016/S0076-6879(02)53070-6  0.8
2002 Majumder S, Ghoshal K, Datta J, Bai S, Dong X, Quan N, Plass C, Jacob ST. Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma. The Journal of Biological Chemistry. 277: 16048-58. PMID 11844796 DOI: 10.1074/jbc.M111662200  0.8
2001 Ghoshal K, Majumder S, Zhu Q, Hunzeker J, Datta J, Shah M, Sheridan JF, Jacob ST. Influenza virus infection induces metallothionein gene expression in the mouse liver and lung by overlapping but distinct molecular mechanisms. Molecular and Cellular Biology. 21: 8301-17. PMID 11713267 DOI: 10.1128/MCB.21.24.8301-8317.2001  0.8
2001 Majumder S, Ghoshal K, Gronostajski RM, Jacob ST. Downregulation of constitutive and heavy metal-induced metallothionein-I expression by nuclear factor I Gene Expression. 9: 203-215. PMID 11444530  0.8
2000 Ghoshal K, Jacob ST. Regulation of metallothionein gene expression Progress in Nucleic Acid Research and Molecular Biology. 66: 357-384. PMID 11051769  0.8
2000 Ghoshal K, Majumder S, Li Z, Dong X, Jacob ST. Suppression of metallothionein gene expression in a rat hepatoma because of promoter-specific DNA methylation. The Journal of Biological Chemistry. 275: 539-47. PMID 10617649 DOI: 10.1074/jbc.275.1.539  0.8
1999 Jacob ST, Ghosh AK. Control of RNA polymerase I-directed transcription: Recent trends Journal of Cellular Biochemistry. 76: 41-50. PMID 10629102  0.8
1999 Majumder S, Ghoshal K, Li Z, Bo Y, Jacob ST. Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation Oncogene. 18: 6287-6295. PMID 10597227  0.8
1999 Ghoshal K, Majumder S, Li Z, Bray TM, Jacob ST. Transcriptional induction of metallothionein-I and -II genes in the livers of Cu,Zn-superoxide dismutase knockout mice. Biochemical and Biophysical Research Communications. 264: 735-42. PMID 10544001 DOI: 10.1006/bbrc.1999.1563  0.8
1999 Majumder S, Ghoshal K, Li Z, Jacob ST. Hypermethylation of metallothionein-I promoter and suppression of its induction in cell lines overexpressing the large subunit of Ku protein Journal of Biological Chemistry. 274: 28584-28589. PMID 10497224 DOI: 10.1074/jbc.274.40.28584  0.8
1999 Jacob ST, Ghoshal K, Sheridan JF. Induction of metallothionein by stress and its molecular mechanisms. Gene Expression. 7: 301-10. PMID 10440231  0.8
1998 Ghoshal K, Wang Y, Sheridan JF, Jacob ST. Metallothionein induction in response to restraint stress. Transcriptional control, adaptation to stress, and role of glucocorticoid. The Journal of Biological Chemistry. 273: 27904-10. PMID 9774402 DOI: 10.1074/jbc.273.43.27904  0.8
1998 Ghoshal K, Li Z, Jacob ST. Overexpression of the large subunit of the protein Ku suppresses metallothionein-I induction by heavy metals Proceedings of the National Academy of Sciences of the United States of America. 95: 10390-10395. PMID 9724713 DOI: 10.1073/pnas.95.18.10390  0.8
1998 Aniskovitch LP, Jacob ST. Distinct rat proteins can recognize CCAAT-homologous sequences of the metallothionein promoter and trans-activate this promoter Oncogene. 16: 1475-1486. PMID 9525746  0.8
1997 Ghoshal K, Jacob ST. An alternative molecular mechanism of action of 5-fluorouracil, a potent anticancer drug Biochemical Pharmacology. 53: 1569-1575. PMID 9264308 DOI: 10.1016/S0006-2952(97)00040-3  0.8
1997 Aniskovitch LP, Jacob ST. Purification and characterization of a rat liver protein that recognizes CCAAT-homologous sequences of the metallothionein promoter and trans- activates this promoter Archives of Biochemistry and Biophysics. 341: 337-346. PMID 9169024 DOI: 10.1006/abbi.1997.9976  0.8
1997 Datta PK, Budhiraja S, Reichel RR, Jacob ST. Regulation of ribosomal RNA gene transcription during retinoic acid- induced differentiation of mouse teratocarcinoma cells Experimental Cell Research. 231: 198-205. PMID 9056427 DOI: 10.1006/excr.1996.3446  0.8
1997 Ghosh AK, Datta PK, Jacob ST. The dual role of helix - loop - helix-zipper protein USF in ribosomal RNA gene transcription in vivo Oncogene. 14: 589-594. PMID 9053857 DOI: 10.1038/sj.onc.1200866  0.8
1997 Datta PK, Jacob ST. Activation of the metallotheionein-1 gene promoter in response to cadmium and USF in vitro Biochemical and Biophysical Research Communications. 230: 159-163. PMID 9020035 DOI: 10.1006/bbrc.1996.5655  0.8
1996 Ghoshal K, Jacob ST. Heat shock inhibits pre-rRNA processing at the primary site in vitro and alters the activity of some rRNA binding proteins Journal of Cellular Biochemistry. 62: 506-515. PMID 8891896 DOI: 10.1002/(SICI)1097-4644(19960915)62:4<506::AID-JCB8>3.0.CO;2-Q  0.8
1996 Ghosh AK, Niu H, Jacob ST. Rat ribosomal RNA gene can utilize primate RNA polymerase I transcription machinery: Lack of absolute species specificity in rDNA transcription Biochemical and Biophysical Research Communications. 225: 890-895. PMID 8780707 DOI: 10.1006/bbrc.1996.1268  0.8
1996 Ghoshal K, Jacob ST. Heat shock selectively inhibits ribosomal RNA gene transcription and down-regulates E1BF/Ku in mouse lymphosarcoma cells Biochemical Journal. 317: 689-695. PMID 8760351 DOI: 10.1042/bj3170689  0.8
1996 Ghosh AK, Datta PK, Jacob ST. Role of use a helix-loop-helk-zipper dna binding protein, in rRNA gene regulation Faseb Journal. 10.  0.8
1995 Niu H, Zhang J, Jacob ST. E1BF/Ku interacts physically and functionally with the core promoter binding factor CPBF and promotes the basal transcription of rat and human ribosomal RNA genes Gene Expression. 4: 111-124. PMID 7734947  0.8
1995 Datta PK, Ghosh AK, Jacob ST. The RNA polymerase I promoter-activating factor CPBF is functionally and immunologically related to the basic helix-loop-helix-zipper DNA-binding protein USF Journal of Biological Chemistry. 270: 8637-8641. PMID 7721765 DOI: 10.1074/jbc.270.15.8637  0.8
1995 Jacob ST. Regulation of ribosomal gene transcription Biochemical Journal. 306: 617-626. PMID 7702552  0.8
1994 Ghoshal K, Jacob ST. Specific Inhibition of Pre-Ribosomal RNA Processing in Extracts from the Lymphosarcoma Cells Treated with 5-Fluorouracil Cancer Research. 54: 632-636. PMID 8306322  0.8
1994 Hoff CM, Ghosh AK, Prabhakar BS, Jacob ST. Enhancer 1 binding factor, a Ku-related protein, is a positive regulator of RNA polymerase I transcription initiation Proceedings of the National Academy of Sciences of the United States of America. 91: 762-766. PMID 8290597 DOI: 10.1073/pnas.91.2.762  0.8
1994 Liu Z, Jacob ST. Characterization of a protein that interacts with the rat ribosomal gene promoter and modulates RNA polymerase I transcription Journal of Biological Chemistry. 269: 16618-16625. PMID 8206980  0.8
1994 Ghosh AK, Kermekchiev M, Jacob ST. Effects of repetitive and non-repetitive rat rDNA enhancer elements on in vivo transcription by RNA polymerases I and II Gene. 141: 271-275. PMID 8163201 DOI: 10.1016/0378-1119(94)90584-3  0.8
1994 Niu H, Jacob ST. Enhancer 1 binding factor (E1BF), a Ku-related protein, is a growth-regulated RNA polymerase I transcription factor: Association of a repressor activity with purified E1BF from serum-deprived cells Proceedings of the National Academy of Sciences of the United States of America. 91: 9101-9105. PMID 8090777 DOI: 10.1073/pnas.91.19.9101  0.8
1993 Ghosh AK, Hoff CM, Jacob ST. Characterization of the 130-bp repeat enhancer element of the rat ribosomal gene: functional interaction with transcription factor E1BF Gene. 125: 217-222. PMID 8462876 DOI: 10.1016/0378-1119(93)90332-W  0.8
1993 Hoff CM, Jacob ST. Characterization of the Factor E1BF from a Rat Hepatoma That Modulates Ribosomal RNA Gene Transcription and Its Relationship to the Human Ku Autoantigen Biochemical and Biophysical Research Communications. 190: 747-753. PMID 8439324 DOI: 10.1006/bbrc.1993.1112  0.8
1993 Reichel RR, Jacob ST. Control of gene expression by lipophilic hormones Faseb Journal. 7: 427-436. PMID 8385039  0.8
1993 Datta PK, Jacob ST. Identification of a sequence within the mouse metallothionein-1 gene promoter mediating its basal transcription and of a protein interacting with this element Cellular and Molecular Biology Research. 39: 439-449. PMID 8173589  0.8
1991 Raju VS, Jacob ST. Anti-poly(a) polymerase antibodies in the sera of tumor-bearing rats can inhibit specific cleavage and polyadenylation reactions Carcinogenesis. 12: 917-920. PMID 2029757 DOI: 10.1093/carcin/12.5.917  0.8
1991 Terns MP, Jacob ST. Potential role of poly(A) polymerase in the assembly of polyadenylation-specific RNP complexes Nucleic Acids Research. 19: 343-351. PMID 2014173 DOI: 10.1093/nar/19.2.343  0.8
1991 Zhang J, Niu H, Jacob ST. E1BF is an essential RNA polymerase I transcription factor with an intrinsic protein kinase activity that can modulate rRNA gene transcription Proceedings of the National Academy of Sciences of the United States of America. 88: 8293-8296. PMID 1924288 DOI: 10.1073/pnas.88.19.8293  0.8
1991 Jacob ST, Zhang J, Garg LC, Book CB. Multiple functional enhancer motifs of rat ribosomal gene Molecular and Cellular Biochemistry. 104: 155-162. PMID 1921995 DOI: 10.1007/BF00229815  0.8
1991 Ghoshal K, Jacob ST. Ara-ATP impairs 3′-end processing of pre-mRNAs by inhibiting both cleavage and polyadenylation Nucleic Acids Research. 19: 5871-5875. PMID 1719481 DOI: 10.1093/nar/19.21.5871  0.8
1991 Chrislip KM, Hengst-Zhang JA, Jacob ST. Polyadenylation of SV40 late pre-mRNA is dependent on phosphorylation of an essential component associated with the 3' end processing machinery Gene Expression. 1: 197-206. PMID 1668146  0.8
1990 Zhang JI, Jacob ST. Purification and characterization of a novel factor which stimulates rat ribosomal gene transcription in vitro by interacting with enhancer and core promoter elements Molecular and Cellular Biology. 10: 5177-5186. PMID 2398888 DOI: 10.1128/MCB.10.10.5177  0.8
1990 Hengst-Zhang JA, Jacob ST. Tissue and species distribution of liver type and tumor type nuclear poly(A) polymerases Biochemical and Biophysical Research Communications. 169: 325-331. PMID 2162661 DOI: 10.1016/0006-291X(90)90335-K  0.8
1990 Jacob ST, Terns MP, Hengst-Zhang JA, Vulapalli RS. Polyadenylation of mRNA and its control Critical Reviews in Eukaryotic Gene Expression. 1: 49-59. PMID 2134348  0.8
1989 Garg LC, Dixit A, Webb ML, Jacob ST. Interaction of a positive regulatory factor(s) with a 106-base pair upstream region controls transcription of metallothionein-I gene in the liver Journal of Biological Chemistry. 264: 2134-2138. PMID 2914896  0.8
1989 Dixit A, Garg LC, Jacob ST. A cis-acting sequence within the rat ribosomal DNA enhancer region can modulate RNA polymerase II-directed transcription of the metallothionein I gene in vitro Dna. 8: 311-320. PMID 2766929  0.8
1989 Garg LC, Dixit A, Jacob ST. A 37-base pair element in the far upstream spacer region can enhance transcription of rat rDNA in vitro and can bind to the core promoter-binding factor(s) Journal of Biological Chemistry. 264: 220-224. PMID 2642473  0.8
1989 Webb ML, Mealey-Cavender JF, Jacob ST. Glucocorticoid-induced stimulation of ribosomal gene transcription in rat hepatoma cells is mediated by modification of RNA polymerase I or an associated factor Molecular Endocrinology. 3: 1861-1868. PMID 2608060 DOI: 10.1210/mend-3-11-1861  0.8
1989 Terns MP, Jacob ST. Role of poly(A) polymerase in the cleavage and polyadenylation of mRNA precursor Molecular and Cellular Biology. 9: 1435-1444. PMID 2566910  0.8
1989 Jacob ST, Terns MP, Maguire KA. Polyadenylate polymerases from normal and cancer cells and their potential role in messenger RNA processing: a review. Cancer Research. 49: 2827-33. PMID 2541894  0.8
1988 Hengst JA, Georgoff I, Isom HC, Jacob ST. Association of newly synthesized poly(A) polymerase with four distinct polypeptides. The Journal of Biological Chemistry. 263: 19270-3. PMID 2848820  0.8
1988 Raju VS, Jacob ST. Association of poly(A) polymerase with U1 RNA Journal of Biological Chemistry. 263: 11067-11070. PMID 2841316  0.8
1988 Webb ML, Jacob ST. Inhibition of RNA polymerase I-directed transcription by novobiocin. Potential use of novobiocin as a general inhibitor of eukaryotic transcription initiation Journal of Biological Chemistry. 263: 4745-4748. PMID 2832404  0.8
1987 Barsoum AL, Webb ML, Balaban CD, Jacob ST. Production of monoclonal antibodies against RNA polymerase I from nonimmunized autoimmune MRL/lpr mice and their use in rDNA transcription analysis. The Journal of Biological Chemistry. 262: 12759-63. PMID 3624276  0.8
1987 Dixit A, Garg LC, Chao W, Jacob ST. An enhancer element in the far upstream spacer region of rat ribosomal RNA gene Journal of Biological Chemistry. 262: 11616-11622. PMID 3624227  0.8
1987 Stetler DA, Reichlin M, Berlin CM, Jacob ST. Autoantibodies against RNA polymerase I in scleroderma and Sjögren's syndrome sera. Biochemical and Biophysical Research Communications. 144: 1296-302. PMID 3579959 DOI: 10.1016/0006-291X(87)91451-3  0.8
1987 Maguire KA, Webb ML, Garg LC, Jacob ST. Accurate transcription of mouse metallothionein-I gene in a fractionated nuclear extract from a rat hepatoma. The Journal of Biological Chemistry. 262: 3932-5. PMID 3558400  0.8
1987 Garg LC, DiAngelo S, Jacob ST. Role of DNA topoisomerase I in the transcription of supercoiled rRNA gene Proceedings of the National Academy of Sciences of the United States of America. 84: 3185-3188. PMID 3033639  0.8
1987 Stetler DA, Reichlin M, Berlin CM, Jacob ST. Antibodies against nuclear poly(A) polymerases in rheumatic autoimmune diseases. Journal of Clinical Immunology. 7: 24-8. PMID 3031126 DOI: 10.1007/BF00915421  0.8
1987 Webb ML, Maguire KA, Jacob ST. Novobiocin inhibits initiation of RNA polymerase II-directed transcription of the mouse metallothionein-I gene independent of its effect on DNA topoisomerase II. Nucleic Acids Research. 15: 8547-60. PMID 2823231 DOI: 10.1093/nar/15.20.8547  0.8
1986 Jacob ST. Transcription of eukaryotic ribosomal RNA gene Molecular and Cellular Biochemistry. 70: 11-20. PMID 3012322 DOI: 10.1007/BF00233800  0.8
1986 Maguire KA, Jacob ST. Cell-free synthesis of tumor-type poly(A) polymerase. Biochemistry. 25: 1515-9. PMID 2423113  0.8
1985 Stetler DA, Sipes DE, Jacob ST. Anti-RNA polymerase I antibodies in sera of MRL lpr/lpr and MRL +/+ autoimmune mice. Correlation of antibody production with delayed onset of lupus-like disease in MRL +/+ mice. The Journal of Experimental Medicine. 162: 1760-70. PMID 3877777  0.8
1985 Stetler DA, Jacob ST. Immunization of rabbits with purified RNA polymerase I induces a distinct population of antibodies against nucleic acids as well as anti-RNA polymerase I antibodies, both characteristic of systemic lupus erythematosus. Proceedings of the National Academy of Sciences of the United States of America. 82: 6797-801. PMID 3863129  0.8
1985 Kurl RN, Jacob ST. Accurate initiation of rat ribosomal RNA gene transcription using a fractionated nuclear extract from normal liver and a hepatoma Proceedings of the National Academy of Sciences of the United States of America. 82: 1059-1063. PMID 3856247  0.8
1985 Stetler DA, Jacob ST. Comparison of cytosolic and nuclear poly(A) polymerases from rat liver and a hepatoma: structural and immunological properties and response to NI-type protein kinases. Biochemistry. 24: 5163-9. PMID 3000424  0.8
1985 Kurl RN, Jacob ST. Characterization of a factor that can prevent random transcription of cloned rDNA and its probable relationship to poly(ADP-ribose) polymerase Nucleic Acids Research. 13: 89-101. PMID 2987793 DOI: 10.1093/nar/13.1.89  0.8
1985 Stetler DA, Jacob ST. Structural and immunological identity of rat hepatoma and fetal liver nuclear poly(A) polymerase. Carcinogenesis. 6: 259-62. PMID 2982514 DOI: 10.1093/carcin/6.2.259  0.8
1984 Seely JE, Stetler DA, Jacob ST, Pegg AE. Absence of inactivation or phosphorylation of ornithine decarboxylase by nuclear protein kinase NII and of immunological cross-reactivity between RNA polymerase I and ornithine decarboxylase. Biochemical and Biophysical Research Communications. 120: 219-25. PMID 6712690 DOI: 10.1016/0006-291X(84)91436-0  0.8
1984 Kurl RN, Jacob ST. Phosphorylation of purified glucocorticoid receptor from rat liver by an endogenous protein kinase Biochemical and Biophysical Research Communications. 119: 700-705. PMID 6712652 DOI: 10.1016/S0006-291X(84)80307-1  0.8
1984 Stetler DA, Rose KM, Wenger ME, Berlin CM, Jacob ST. Anti-protein kinase NII antibodies in rheumatic autoimmune diseases. The Journal of Biological Chemistry. 259: 2077-9. PMID 6698957  0.8
1984 Mercer WE, Avignolo C, Galanti N, Rose KM, Hyland JK, Jacob ST, Baserga R. Cellular DNA replication is independent of the synthesis or accumulation of ribosomal RNA Experimental Cell Research. 150: 118-130. PMID 6692843 DOI: 10.1016/0014-4827(84)90707-9  0.8
1984 Kurl RN, Rothblum LI, Jacob ST. A purified fraction containing RNA polymerase I that can accurately transcribe rat ribosomal RNA gene Proceedings of the National Academy of Sciences of the United States of America. 81: 6672-6675. PMID 6593724  0.8
1984 Stetler DA, Jacob ST. Phosphorylation of RNA polymerase I augments its interaction with autoantibodies of systemic lupus erythematosus patients. The Journal of Biological Chemistry. 259: 13629-32. PMID 6501273  0.8
1984 Stetler DA, Jacob ST. Structurally and immunologically distinct poly(A) polymerases in rat liver. Occurrence of a tumor-type enzyme in normal liver. The Journal of Biological Chemistry. 259: 7239-44. PMID 6327712  0.8
1984 Stetler DA, Seidel BL, Jacob ST. Purification and characterization of a nuclear protein kinase from rat liver and a hepatoma that is capable of activating poly(A) polymerase. The Journal of Biological Chemistry. 259: 14481-5. PMID 6094560  0.8
1984 Stetler DA, Wrenshall LE, Park Y, Jacob ST. Induction of a distinct nuclear poly(A) polymerase and the production of anti-tumor poly(A) polymerase antibodies in hepatocarcinogenesis. Carcinogenesis. 5: 1363-6. PMID 6091938 DOI: 10.1093/carcin/5.10.1363  0.8
1984 Jacob ST, Rose KM. Phosphorylation and immunology of poly(A) polymerase Advances in Enzyme Regulation. 22: 485-497. PMID 6089516 DOI: 10.1016/0065-2571(84)90027-X  0.8
1984 Stetler DA, Jacob ST. Structurally and immunologically distinct nuclear poly(a) polymerases from rat liver and hepatomas Federation Proceedings. 43: no. 16.  0.8
1984 Kurl RN, Rothblum LT, Jacob ST. Partial purification of factors necessary for faithful transcription of rat rDNA in a cell free system Federation Proceedings. 43.  0.8
1983 Jacob ST, Stetler DA, Rose KM. Regulation of RNA polymerase I by phosphorylation and production of anti-RNA polymerase I antibodies in rheumatic autoimmune diseases. Isozymes. 7: 263-75. PMID 6604044  0.8
1983 Rose KM, Duceman BW, Stetler D, Jacob ST. RNA polymerase I in hepatoma 3924A: mechanism of enhanced activity relative to liver. Advances in Enzyme Regulation. 21: 307-19. PMID 6545082 DOI: 10.1016/0065-2571(83)90020-1  0.8
1983 Rose KM, Stetler DA, Jacob ST. Phosphorylation of RNA polymerases: specific association of protein kinase NII with RNA polymerase I. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 302: 135-42. PMID 6137001  0.8
1982 Stetler DA, Rose KM, Wenger ME, Berlin CM, Jacob ST. Antibodies to distinct polypeptides of RNA polymerase I in sera from patients with rheumatic autoimmune disease. Proceedings of the National Academy of Sciences of the United States of America. 79: 7499-503. PMID 6961426 DOI: 10.1073/pnas.79.23.7499  0.8
1981 Jacob ST, Duceman BW, Rose KM. Spermine-mediated phosphorylation of RNA polymerase I and its effect on transcription Medical Biology. 59: 381-388. PMID 7339301  0.8
1981 Duceman BW, Rose KM, Jacob ST. Activation of purified hepatoma RNA polymerase I by homologous protein kinase NII Journal of Biological Chemistry. 256: 10755-10758. PMID 7287732  0.8
1981 Rose KM, Bell LE, Siefken DA, Jacob ST. A heparin-sensitive nuclear protein kinase. Purification, properties, and increased activity in rat hepatoma relative to liver Journal of Biological Chemistry. 256: 7468-7477. PMID 7251604  0.8
1981 Rose KM, Duceman BW, Jacob ST. RNA polymerases in neoplasia Isozymes. 5: 115-141. PMID 7035399  0.8
1981 Rose KM, Stetler DA, Jacob ST. Protein kinase activity of RNA polymerase I purified from a rat hepatoma: probable function of Mr 42,000 and 24,600 polypeptides. Proceedings of the National Academy of Sciences of the United States of America. 78: 2833-7. PMID 6942406  0.8
1981 Stetler DA, Rose KM, Jacob ST. Anti-poly(A) polymerase antibodies in sera of tumor-bearing rats and human cancer patients. Proceedings of the National Academy of Sciences of the United States of America. 78: 7732-6. PMID 6278486  0.8
1980 Duceman BW, Jacob ST. Transcriptionally active RNA polymerases from Morris hepatomas and rat liver. Elucidation of the mechanism for the preferential increase in the tumour RNA polymerase I Biochemical Journal. 190: 781-789. PMID 7470079  0.8
1980 Abraham AK, Pihl A, Jacob ST. Turnover of the poly(A) moiety of mRNA in wheat-germ extract. European Journal of Biochemistry / Febs. 110: 1-5. PMID 7439152 DOI: 10.1111/j.1432-1033.1980.tb04836.x  0.8
1980 Rose KM, Jacob ST. Phosphorylation of nuclear poly(adenylic acid) polymerase by protein kinase: Mechanism of enhanced poly(adenylic acid) synthesis Biochemistry. 19: 1472-1476. PMID 6248104  0.8
1979 Leonard TB, Jacob ST. Differential effects of cordycepin triphosphate and 9 beta-D-arabinofuranosyladenine triphosphate on tRNA and 5 S RNA synthesis in isolated nuclei. Biochimica Et Biophysica Acta. 563: 150-4. PMID 497205 DOI: 10.1016/0005-2787(79)90015-7  0.8
1979 Rose KM, Jacob ST. Phosphorylation of nuclear poly(A) polymerase. Comparison of liver and hepatoma enzymes Journal of Biological Chemistry. 254: 10256-10261. PMID 489595  0.8
1979 Rose KM, Jacob ST, Kumar A. Poly(A) polymerase and poly(A)-specific mRNA binding protein are antigenically related [24] Nature. 279: 260-262. PMID 86957 DOI: 10.1038/279260a0  0.8
1978 Jacob ST. Effect of medroxyprogesterone acetate and testosterone on solubilized RNA polymerases and chromatin template activity in kidney from normal and androgen-insensitive (Tfm/Y) mice Biochemistry. 17: 4833-4838. PMID 728389  0.8
1978 Rose KM, Jacob ST. Selective inhibition of RNA polyadenylation by Ara-ATP in vitro: A possible mechanism for antiviral action of Ara-A Biochemical and Biophysical Research Communications. 81: 1418-1424. PMID 666826 DOI: 10.1016/0006-291X(78)91294-9  0.8
1978 ROSE KM, ALLEN MS, CRAWFORD IL, JACOB ST. Functional Role of Zinc in Poly(A) Synthesis Catalyzed by Nuclear Poly(A) Polymerase European Journal of Biochemistry. 88: 29-36. PMID 208847 DOI: 10.1111/j.1432-1033.1978.tb12419.x  0.8
1978 Abraham AK, Jacob ST. Hydrolysis of poly (A) to adenine nucleotides by purified poly (A) polymerase. Proceedings of the National Academy of Sciences of the United States of America. 75: 2085-7. PMID 27783  0.8
1977 Leonard TB, Jacob ST. Alterations in DNA-dependent RNA polymerase I and II from rat liver by thioacetamide: preferential increase in the level of chromatin-associated nucleolar RNA polymerase IB. Biochemistry. 16: 4538-44. PMID 911772  0.8
1977 Rose KM, Roe FJ, Jacob ST. Two functional states of poly(adenylic acid) polymerase in isolated nuclei Bba Section Nucleic Acids and Protein Synthesis. 478: 180-191. PMID 901792 DOI: 10.1016/0005-2787(77)90181-2  0.8
1977 Duceman BW, Jacob ST. Three distinct forms of DNA-dependent RNA polymerase III from kidney Biochemical and Biophysical Research Communications. 74: 884-890. PMID 843358 DOI: 10.1016/0006-291X(77)91601-1  0.8
1977 Rose KM, Bell LE, Jacob ST. Selective inhibition of initial polyadenylation in isolated nuclei by low levels of cordycepin 5′-triphosphate Bba Section Nucleic Acids and Protein Synthesis. 475: 548-552. PMID 300631 DOI: 10.1016/0005-2787(77)90069-7  0.8
1977 Jacob ST, Rose KM, Leonard TB, Duceman BW. DNA-dependent RNA polymerases from Morris hepatomas 3924A and 7800 and from liver treated with thioacetamide. Advances in Experimental Medicine and Biology. 92: 273-88. PMID 205100  0.8
1977 Rose KM, Bell LE, Jacob ST. Specific inhibition of chromatin-associated poly(A) synthesis in vitro by cordycepin 5′-triphosphate [33] Nature. 267: 178-180. DOI: 10.1038/267178a0  0.8
1977 Rose KM, Jacob ST. Specific inhibition of poly(adenylic acid) synthesis in vitro by cordycepin 5' triphosphate Federation Proceedings. 36.  0.8
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