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Tomoyuki Yamanaka, Ph.D. - Publications

Affiliations: 
Laboratory for Structural Neuropathology RIKEN Brain Science Institute, Wakō-shi, Saitama-ken, Japan 
Area:
polyglutamine disorders
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Miyazaki H, Nishioka S, Yamanaka T, Abe M, Imamura Y, Miyasaka T, Kakuda N, Oohashi T, Shimogori T, Yamakawa K, Ikawa M, Nukina N. Generation and characterization of cerebellar granule neurons specific knockout mice of Golli-MBP. Transgenic Research. PMID 38684589 DOI: 10.1007/s11248-024-00382-0  0.517
2024 Yamanaka T, Kurosawa M, Yoshida A, Shimogori T, Hiyama A, Maity SN, Hattori N, Matsui H, Nukina N. The Transcription factor NF-YA is Crucial for Neural Progenitor Maintenance during Brain Development. The Journal of Biological Chemistry. 105629. PMID 38199563 DOI: 10.1016/j.jbc.2024.105629  0.554
2022 Park H, Yamanaka T, Nukina N. Proteomic analysis of heat-stable proteins revealed an increased proportion of proteins with compositionally biased regions. Scientific Reports. 12: 4347. PMID 35289333 DOI: 10.1038/s41598-022-08044-z  0.489
2022 Imamura Y, Hiyama A, Miyazaki H, Yamanaka T, Nukina N. Amyloids facilitate DNA transfection in vivo. Neuroscience Research. PMID 35283247 DOI: 10.1016/j.neures.2022.03.003  0.625
2022 Park H, Yamanaka T, Toyama Y, Fujita A, Doi H, Nirasawa T, Murayama S, Matsumoto N, Shimogori T, Ikegawa M, Haltia MJ, Nukina N. Hornerin deposits in neuronal intranuclear inclusion disease: direct identification of proteins with compositionally biased regions in inclusions. Acta Neuropathologica Communications. 10: 28. PMID 35246273 DOI: 10.1186/s40478-022-01333-8  0.527
2021 Borgese N, Navone F, Nukina N, Yamanaka T. Mutant VAPB: Culprit or Innocent Bystander of Amyotrophic Lateral Sclerosis? Contact (Thousand Oaks (Ventura County, Calif.)). 4: 25152564211022515. PMID 37366377 DOI: 10.1177/25152564211022515  0.545
2020 Kasahara J, Imamura Y, Hiyama A, Yamanaka T, Miyazaki H, Nukina N. Proteomic Analysis of Subcellular Compartments Containing Disseminated Alpha-synuclein Seeds. Neuroscience Research. PMID 33309865 DOI: 10.1016/j.neures.2020.11.009  0.594
2020 Yamanaka T, Miyazaki H, Tosaki A, Maity SN, Shimogori T, Hattori N, Nukina N. Gene expression profiling in neuronal cells identifies a different type of transcriptome modulated by NF-Y. Scientific Reports. 10: 21714. PMID 33303918 DOI: 10.1038/s41598-020-78682-8  0.643
2020 Miyazaki H, Yamanaka T, Oyama F, Kino Y, Kurosawa M, Yamada-Kurosawa M, Yamano R, Shimogori T, Hattori N, Nukina N. FACS array-based cell purification yields a specific transcriptome of striatal medium spiny neurons in a murine Huntington disease model. The Journal of Biological Chemistry. PMID 32499373 DOI: 10.1074/Jbc.Ra120.012983  0.718
2020 Yamanaka T, Nishiyama R, Shimogori T, Nukina N. Proteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation. Scientific Reports. 10: 7610. PMID 32376919 DOI: 10.1038/S41598-020-64517-Z  0.54
2019 Yoshinaga S, Yamanaka T, Miyazaki H, Okuzumi A, Hiyama A, Murayama S, Nukina N. Preserved proteinase K-resistant core after amplification of alpha-synuclein aggregates: Implication to disease-related structural study. Biochemical and Biophysical Research Communications. PMID 31785806 DOI: 10.1016/J.Bbrc.2019.11.142  0.635
2019 Tanaka G, Yamanaka T, Furukawa Y, Kajimura N, Mitsuoka K, Nukina N. Sequence- and seed-structure-dependent polymorphic fibrils of alpha-synuclein. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30790619 DOI: 10.1016/J.Bbadis.2019.02.013  0.558
2019 Tanaka G, Yamanaka T, Furukawa Y, Kajimura N, Mitsuoka K, Nukina N. Biochemical and morphological classification of disease-associated alpha-synuclein mutants aggregates. Biochemical and Biophysical Research Communications. 508: 729-734. PMID 30528390 DOI: 10.1016/J.Bbrc.2018.11.200  0.569
2018 Park H, Miyazaki H, Yamanaka T, Nukina N. Non-coding RNA Neat1 and Abhd11os expressions are dysregulated in medium spiny neurons of Huntington disease model mice. Neuroscience Research. PMID 30391555 DOI: 10.1016/J.Neures.2018.10.013  0.669
2018 Okuzumi A, Kurosawa M, Hatano T, Takanashi M, Nojiri S, Fukuhara T, Yamanaka T, Miyazaki H, Yoshinaga S, Furukawa Y, Shimogori T, Hattori N, Nukina N. Rapid dissemination of alpha-synuclein seeds through neural circuits in an in-vivo prion-like seeding experiment. Acta Neuropathologica Communications. 6: 96. PMID 30231908 DOI: 10.1186/S40478-018-0587-0  0.629
2018 Yamanaka T, Nukina N. ER Dynamics and Derangement in Neurological Diseases. Frontiers in Neuroscience. 12: 91. PMID 29515361 DOI: 10.3389/Fnins.2018.00091  0.519
2017 Yoshinaga S, Yamanaka T, Furukawa Y, Nukina N. The detection of seeds alpha-synuclein using protein misfolding cyclic amplification(PMCA) Journal of the Neurological Sciences. 381: 972-973. DOI: 10.1016/J.Jns.2017.08.2740  0.512
2017 Tanaka G, Yamanaka T, Furukawa Y, Nukina N. Amyloid polymorphism derived from human and mouse alpha-synuclein Journal of the Neurological Sciences. 381: 966. DOI: 10.1016/J.Jns.2017.08.2721  0.501
2017 Yamanaka T, Nukina N. NF-Y inactivation induces differential ER chaperone downregulations and UBIQUITIN/P62 pathologies in the CNS Journal of the Neurological Sciences. 381: 719. DOI: 10.1016/J.Jns.2017.08.2026  0.536
2017 Miyazaki H, Oyama F, Kino Y, Kurosawa M, Yamada-Kurosawa M, Yamanaka T, Shimogori T, Hattori N, Nukina N. Gene expression profiling of medium spiny neurons in Huntington’s disease model mouse Journal of the Neurological Sciences. 381: 583. DOI: 10.1016/J.Jns.2017.08.1643  0.713
2016 Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Koike M, Uchiyama Y, Maity SN, Misawa H, Takahashi R, Shimogori T, Hattori N, Nukina N. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Scientific Reports. 6: 34575. PMID 27687130 DOI: 10.1038/Srep34575  0.677
2016 Misawa H, Inomata D, Kikuchi M, Maruyama S, Moriwaki Y, Okuda T, Nukina N, Yamanaka T. Reappraisal of VAChT-Cre: Preference in Slow Motor Neurons Innervating Type I or IIa Muscle Fibers. Genesis (New York, N.Y. : 2000). PMID 27596971 DOI: 10.1002/Dvg.22979  0.545
2016 Yamanaka T, Tosaki A, Kurosawa M, Shimogori T, Hattori N, Nukina N. Genome-wide analyses in neuronal cells reveal that USF transcription factors regulate lysosomal gene expression. The Febs Journal. PMID 26756308 DOI: 10.1111/Febs.13650  0.607
2014 Yamanaka T, Wong HK, Tosaki A, Bauer PO, Wada K, Kurosawa M, Shimogori T, Hattori N, Nukina N. Large-scale RNA interference screening in mammalian cells identifies novel regulators of mutant huntingtin aggregation. Plos One. 9: e93891. PMID 24705917 DOI: 10.1371/Journal.Pone.0093891  0.616
2014 Yamanaka T, Tosaki A, Kurosawa M, Matsumoto G, Koike M, Uchiyama Y, Maity SN, Shimogori T, Hattori N, Nukina N. NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization. Nature Communications. 5: 3354. PMID 24566496 DOI: 10.1038/Ncomms4354  0.685
2013 Yamanaka T, Tosaki A, Kurosawa M, Akimoto K, Hirose T, Ohno S, Hattori N, Nukina N. Loss of aPKCλ in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brains. Plos One. 8: e84036. PMID 24391875 DOI: 10.1371/Journal.Pone.0084036  0.607
2011 Yamanaka T, Tosaki A, Wong HK, Bauer PO, Wada K, Nukina N. Establishment of method for counting of polyglutamine aggregates by Array Scan reader and its application for shRNA high-throughput screening Neuroscience Research. 71: e192. DOI: 10.1016/J.Neures.2011.07.830  0.49
2010 Yamanaka T, Nukina N. Transcription factor sequestration by polyglutamine proteins. Methods in Molecular Biology (Clifton, N.J.). 648: 215-29. PMID 20700715 DOI: 10.1007/978-1-60761-756-3_14  0.628
2010 Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Furukawa Y, Yamada M, Nukina N. Mutant huntingtin fragment selectively suppresses Brn-2 POU domain transcription factor to mediate hypothalamic cell dysfunction. Human Molecular Genetics. 19: 2099-112. PMID 20185558 DOI: 10.1093/Hmg/Ddq087  0.685
2009 Masuda-Hirata M, Suzuki A, Amano Y, Yamashita K, Ide M, Yamanaka T, Sakai M, Imamura M, Ohno S. Intracellular polarity protein PAR-1 regulates extracellular laminin assembly by regulating the dystroglycan complex. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 14: 835-50. PMID 19549170 DOI: 10.1111/J.1365-2443.2009.01315.X  0.306
2009 Horikoshi Y, Suzuki A, Yamanaka T, Sasaki K, Mizuno K, Sawada H, Yonemura S, Ohno S. Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells. Journal of Cell Science. 122: 1595-606. PMID 19401335 DOI: 10.1242/Jcs.043174  0.331
2009 Iwata A, Nagashima Y, Matsumoto L, Suzuki T, Yamanaka T, Date H, Deoka K, Nukina N, Tsuji S. Intranuclear degradation of polyglutamine aggregates by the ubiquitin-proteasome system. The Journal of Biological Chemistry. 284: 9796-803. PMID 19218238 DOI: 10.1074/Jbc.M809739200  0.598
2008 Yamanaka T, Miyazaki H, Oyama F, Kurosawa M, Washizu C, Doi H, Nukina N. Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor. The Embo Journal. 27: 827-39. PMID 18288205 DOI: 10.1038/Emboj.2008.23  0.672
2008 Khan LA, Yamanaka T, Nukina N. Genetic impairment of autophagy intensifies expanded polyglutamine toxicity in Caenorhabditis elegans. Biochemical and Biophysical Research Communications. 368: 729-35. PMID 18261464 DOI: 10.1016/J.Bbrc.2008.01.150  0.598
2005 Yasumi M, Sakisaka T, Hoshino T, Kimura T, Sakamoto Y, Yamanaka T, Ohno S, Takai Y. Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division. The Journal of Biological Chemistry. 280: 6761-5. PMID 15632202 DOI: 10.1074/Jbc.C400440200  0.308
2003 Yamanaka T, Horikoshi Y, Sugiyama Y, Ishiyama C, Suzuki A, Hirose T, Iwamatsu A, Shinohara A, Ohno S. Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity. Current Biology : Cb. 13: 734-43. PMID 12725730 DOI: 10.1016/S0960-9822(03)00244-6  0.306
2001 Yamanaka T, Horikoshi Y, Suzuki A, Sugiyama Y, Kitamura K, Maniwa R, Nagai Y, Yamashita A, Hirose T, Ishikawa H, Ohno S. PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induces formation of the epithelial junctional complex Genes to Cells. 6: 721-731. PMID 11532031 DOI: 10.1046/J.1365-2443.2001.00453.X  0.316
2001 Suzuki A, Yamanaka T, Hirose T, Manabe N, Mizuno K, Shimizu M, Akimoto K, Izumi Y, Ohnishi T, Ohno S. Atypical protein kinase C is involved in the evolutionarily conserved PAR protein complex and plays a critical role in establishing epithelia-specific junctional structures Journal of Cell Biology. 152: 1183-1196. PMID 11257119 DOI: 10.1083/Jcb.152.6.1183  0.313
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