| Year |
Citation |
Score |
| 2024 |
Zhang J, Sabatier JM, Chahine M, Tricarico D. Editorial: Reviews in pharmacology of ion channels and channelopathies. Frontiers in Pharmacology. 15: 1449967. PMID 39228529 DOI: 10.3389/fphar.2024.1449967 |
0.319 |
|
| 2024 |
Djemai M, Jalouli M, Chahine M. Impacts of DCM-linked gating pore currents on the electrophysiological characteristics of hiPSC-CM monolayers. Biochemical and Biophysical Research Communications. 723: 150175. PMID 38820625 DOI: 10.1016/j.bbrc.2024.150175 |
0.38 |
|
| 2024 |
Sourisseau F, Chahine C, Pouliot V, Cens T, Charnet P, Chahine M. Cloning, functional expression, and pharmacological characterization of inwardly rectifying potassium channels (Kir) from Apis mellifera. Scientific Reports. 14: 7834. PMID 38570597 DOI: 10.1038/s41598-024-58234-0 |
0.472 |
|
| 2024 |
Bertaud A, Cens T, Chavanieu A, Estaran S, Rousset M, Soussi L, Ménard C, Kadala A, Collet C, Dutertre S, Bois P, Gosselin-Badaroudine P, Thibaud JB, Roussel J, Vignes M, ... Chahine M, et al. Honeybee CaV4 has distinct permeation, inactivation, and pharmacology from homologous NaV channels. The Journal of General Physiology. 156. PMID 38557788 DOI: 10.1085/jgp.202313509 |
0.454 |
|
| 2023 |
Chapotte-Baldacci CA, Pierre M, Djemai M, Pouliot V, Chahine M. Biophysical properties of Na1.5 channels from atrial-like and ventricular-like cardiomyocytes derived from human induced pluripotent stem cells. Scientific Reports. 13: 20685. PMID 38001331 DOI: 10.1038/s41598-023-47310-6 |
0.38 |
|
| 2023 |
Pierre M, Djemai M, Chapotte-Baldacci CA, Pouliot V, Puymirat J, Boutjdir M, Chahine M. Cardiac involvement in patient-specific induced pluripotent stem cells of myotonic dystrophy type 1: unveiling the impact of voltage-gated sodium channels. Frontiers in Physiology. 14: 1258318. PMID 37791351 DOI: 10.3389/fphys.2023.1258318 |
0.315 |
|
| 2022 |
Plumereau Q, Ebdalla A, Poulin H, Appendino JP, Scantlebury MH, Au PYB, Chahine M. De novo Y1460C missense variant in Na1.1 impedes the pore region and results in epileptic encephalopathy. Scientific Reports. 12: 17182. PMID 36229510 DOI: 10.1038/s41598-022-22208-x |
0.457 |
|
| 2022 |
Gamal El-Din TM, Zimmer T, Chahine M. Editorial: Structure Related Druggability of Voltage-Gated Sodium and Calcium Ion-Channels to Treat Diseases. Frontiers in Pharmacology. 13: 947511. PMID 35784759 DOI: 10.3389/fphar.2022.947511 |
0.346 |
|
| 2022 |
Yang XR, Ginjupalli VKM, Theriault O, Poulin H, Appendino JP, Au PYB, Chahine M. -related epilepsy of infancy with migrating focal seizures: report of a variant with apparent gain- and loss-of-function effects. Journal of Neurophysiology. 127: 1388-1397. PMID 35417276 DOI: 10.1152/jn.00309.2021 |
0.306 |
|
| 2022 |
Hui JB, Silva JCH, Pelaez MC, Sévigny M, Venkatasubramani JP, Plumereau Q, Chahine M, Proulx CD, Sephton CF, Dutchak PA. NPRL2 Inhibition of mTORC1 Controls Sodium Channel Expression and Brain Amino Acid Homeostasis. Eneuro. 9. PMID 35165201 DOI: 10.1523/ENEURO.0317-21.2022 |
0.343 |
|
| 2021 |
Pierre M, Djemai M, Poulin H, Chahine M. Na1.5 knockout in iPSCs: a novel approach to study Na1.5 variants in a human cardiomyocyte environment. Scientific Reports. 11: 17168. PMID 34433864 DOI: 10.1038/s41598-021-96474-6 |
0.414 |
|
| 2021 |
Plumereau Q, Theriault O, Pouliot V, Moreau A, Morel E, Fressart V, Denjoy I, Delinière A, Bessière F, Chevalier P, Gamal El-Din TM, Chahine M. Novel G1481V and Q1491H SCN5A Mutations Linked to Long QT Syndrome Destabilize the Nav1.5 Inactivation State. Cjc Open. 3: 256-266. PMID 33778442 DOI: 10.1016/j.cjco.2020.09.023 |
0.434 |
|
| 2021 |
Poulin H, Mercier A, Djemai M, Pouliot V, Deschenes I, Boutjdir M, Puymirat J, Chahine M. iPSC-derived cardiomyocytes from patients with myotonic dystrophy type 1 have abnormal ion channel functions and slower conduction velocities. Scientific Reports. 11: 2500. PMID 33510259 DOI: 10.1038/s41598-021-82007-8 |
0.69 |
|
| 2021 |
Poulin H, Chahine M. R1617Q epilepsy mutation slows Na 1.6 sodium channel inactivation and increases the persistent current and neuronal firing. The Journal of Physiology. PMID 33442870 DOI: 10.1113/JP280838 |
0.459 |
|
| 2020 |
Dong W, Jin SC, Allocco A, Zeng X, Sheth AH, Panchagnula S, Castonguay A, Lorenzo LÉ, Islam B, Brindle G, Bachand K, Hu J, Sularz A, Gaillard J, Choi J, ... ... Chahine M, et al. Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia. Iscience. 23: 101552. PMID 33083721 DOI: 10.1016/J.Isci.2020.101552 |
0.404 |
|
| 2020 |
Srivastava U, Jennings-Charles R, Qu YS, Sossalla S, Chahine M, Boutjdir M. Novel Re-expression of L-type Calcium Channel Ca1.3 in Left Ventricles of Failing Human Heart. Heart Rhythm. PMID 32113898 DOI: 10.1016/J.Hrthm.2020.02.025 |
0.403 |
|
| 2019 |
Kadala A, Charreton M, Charnet P, Cens T, Rousset M, Chahine M, Vaissière BE, Collet C. Voltage-gated sodium channels from the bees Apis mellifera and Bombus terrestris are differentially modulated by pyrethroid insecticides. Scientific Reports. 9: 1078. PMID 30705348 DOI: 10.1038/S41598-018-37278-Z |
0.458 |
|
| 2019 |
Thériault O, Rousset M, Claude C, Cens T, Charnet P, Chahine M. Biophysical and Molecular Characterization of Calcium Permeable Honeybee DSC1 (AmCaV4) Channel Expressed in Mammalian Cells Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.2112 |
0.446 |
|
| 2018 |
Mechakra A, Footz T, Walter M, Aránega A, Hernández-Torres F, Morel E, Millat G, Yang YQ, Chahine M, Chevalier P, Christé G. A Novel PITX2c Gain-of-Function Mutation, p.Met207Val, in Patients With Familial Atrial Fibrillation. The American Journal of Cardiology. PMID 30558760 DOI: 10.1016/J.Amjcard.2018.11.047 |
0.429 |
|
| 2018 |
Kokunai Y, Dalle C, Vicart S, Sternberg D, Pouliot V, Bendahhou S, Fournier E, Chahine M, Fontaine B, Nicole S. A204E mutation in Na1.4 DIS3 exerts gain- and loss-of-function effects that lead to periodic paralysis combining hyper- with hypo-kalaemic signs. Scientific Reports. 8: 16681. PMID 30420713 DOI: 10.1038/S41598-018-34750-8 |
0.471 |
|
| 2018 |
Moreau A, Chahine M. A New Cardiac Channelopathy: From Clinical Phenotypes to Molecular Mechanisms Associated With Na1.5 Gating Pores. Frontiers in Cardiovascular Medicine. 5: 139. PMID 30356750 DOI: 10.3389/Fcvm.2018.00139 |
0.55 |
|
| 2018 |
Moreau A, Gosselin-Badaroudine P, Mercier A, Burger B, Keller DI, Chahine M. A leaky voltage sensor domain of cardiac sodium channels causes arrhythmias associated with dilated cardiomyopathy. Scientific Reports. 8: 13804. PMID 30218094 DOI: 10.1038/S41598-018-31772-0 |
0.505 |
|
| 2018 |
Chahine M. Improving the characterization of calcium channel gating pore currents with Stac3. The Journal of General Physiology. PMID 29467165 DOI: 10.1085/Jgp.201711984 |
0.518 |
|
| 2018 |
Poulin H, Gosselin-Badaroudine P, Vicart S, Habbout K, Sternberg D, Giuliano S, Fontaine B, Bendahhou S, Nicole S, Chahine M. Substitutions of the S4DIV R2 residue (R1451) in NaV1.4 lead to complex forms of paramyotonia congenita and periodic paralyses. Scientific Reports. 8: 2041. PMID 29391559 DOI: 10.1038/S41598-018-20468-0 |
0.457 |
|
| 2017 |
O’Leary ME, Chahine M. Mechanisms of Drug Binding to Voltage-Gated Sodium Channels. Handbook of Experimental Pharmacology. 246: 209-231. PMID 29138928 DOI: 10.1007/164_2017_73 |
0.583 |
|
| 2017 |
Gosselin-Badaroudine P, Charnet P, Collet C, Chahine M. Metaflumizone inhibits the honeybee NaV 1 channel by targeting recovery from slow inactivation. Febs Letters. PMID 29105054 DOI: 10.1002/1873-3468.12897 |
0.54 |
|
| 2017 |
Aromolaran AS, Chahine M, Boutjdir M. Regulation of Cardiac Voltage-Gated Sodium Channel by Kinases: Roles of Protein Kinases A and C. Handbook of Experimental Pharmacology. PMID 29032483 DOI: 10.1007/164_2017_53 |
0.558 |
|
| 2017 |
Gosselin-Badaroudine P, Chahine M. Biophysical characterization of the Varroa destructor NaV1 sodium channel and its affinity for τ-fluvalinate insecticide. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28356346 DOI: 10.1096/Fj.201601338R |
0.556 |
|
| 2017 |
Moreau A, Boutjdir M, Chahine M. Induced Pluripotent Stem Cell-derived Cardiomyocytes: Cardiac Applications, Opportunities and Challenges. Canadian Journal of Physiology and Pharmacology. PMID 28350968 DOI: 10.1139/Cjpp-2016-0726 |
0.318 |
|
| 2017 |
Rousset M, Collet C, Cens T, Bastin F, Raymond V, Massou I, Menard C, Thibaud JB, Charreton M, Vignes M, Chahine M, Sandoz JC, Charnet P. Honeybee locomotion is impaired by Am-CaV3 low voltage-activated Ca(2+) channel antagonist. Scientific Reports. 7: 41782. PMID 28145504 DOI: 10.1038/Srep41782 |
0.474 |
|
| 2017 |
Moreau A, Mercier A, Chahine M. Biophysical, Molecular, and Pharmacological Characterization of Na V Channels from Induced Pluripotent Stem Cell-Derived Cardiomyocytes Biophysical Journal. 112: 241a. DOI: 10.1016/J.Bpj.2016.11.1317 |
0.511 |
|
| 2016 |
Moreau A, Mercier A, Thériault O, Boutjdir M, Burger B, Keller DI, Chahine M. Biophysical, Molecular, and Pharmacological Characterization of Voltage-Dependent Sodium Channels From Induced Pluripotent Stem Cell-Derived Cardiomyocytes. The Canadian Journal of Cardiology. PMID 27998617 DOI: 10.1016/J.Cjca.2016.10.001 |
0.528 |
|
| 2016 |
Gosselin-Badaroudine P, Moreau A, Simard L, Cens T, Rousset M, Collet C, Charnet P, Chahine M. Biophysical characterization of the honeybee DSC1 orthologue reveals a novel voltage-dependent Ca2+ channel subfamily: CaV4. The Journal of General Physiology. PMID 27432995 DOI: 10.1085/Jgp.201611614 |
0.532 |
|
| 2016 |
Fabris F, Yue Y, Qu Y, Chahine M, Sobie E, Lee P, Wieczorek R, Jiang XC, Capecchi PL, Laghi-Pasini F, Lazzerini PE, Boutjdir M. Induction of autoimmune response to the extracellular loop of the HERG channel pore induces QTc prolongation in guinea pigs. The Journal of Physiology. PMID 27296897 DOI: 10.1113/Jp272151 |
0.362 |
|
| 2016 |
Chahine M, Desaphy JF. Editorial: Recent Advances in Voltage-Gated Sodium Channels, their Pharmacology and Related Diseases. Frontiers in Pharmacology. 7: 20. PMID 26903866 DOI: 10.3389/Fphar.2016.00020 |
0.486 |
|
| 2016 |
Collet C, Kadala A, Vaissière B, Rousset M, Cens T, Conte YL, Chahine M, Thibaud J, Charnet P. Differential Action of Pyrethroids on Honey Bee and Bumble Bee Voltage-Gated Sodium Channels Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.660 |
0.518 |
|
| 2016 |
Gosselin-Badaroudine P, Moreau A, Simard L, Cens T, Rousset M, Charnet P, Chahine M. Biophysical Characterization of the Honeybee's DSC1 Ortholog Highlights a New Voltage Dependant Calcium Channel Subfamily Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.253 |
0.546 |
|
| 2016 |
Poulin H, Gosselin-Badaroudine P, Habbout K, Vicart S, Syternberg D, Giuliano S, Nicole S, Bendahhou S, Chahine M. Biophysical Characterization of Two Nav1.4 Mutations Identified in Patients with Cold-Induced Myotonia and Periodic Paralysis Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2360 |
0.47 |
|
| 2016 |
Aromolaran KA, Chang DD, Zukin RS, Colecraft HM, Chahine M, Boutjdir M, Aromolaran A. Modulation of hERG 1a Trafficking by hERG 1b Subunits in Heart Biophysical Journal. 110: 273a. DOI: 10.1016/J.Bpj.2015.11.1483 |
0.354 |
|
| 2015 |
Moreau A, Gosselin-Badaroudine P, Boutjdir M, Chahine M. Mutations in the Voltage Sensors of Domains I and II of Nav1.5 that are Associated with Arrhythmias and Dilated Cardiomyopathy Generate Gating Pore Currents. Frontiers in Pharmacology. 6: 301. PMID 26733869 DOI: 10.3389/Fphar.2015.00301 |
0.554 |
|
| 2015 |
Habbout K, Poulin H, Rivier F, Giuliano S, Sternberg D, Fontaine B, Eymard B, Morales RJ, Echenne B, King L, Hanna MG, Männikkö R, Chahine M, Nicole S, Bendahhou S. A recessive Nav1.4 mutation underlies congenital myasthenic syndrome with periodic paralysis. Neurology. PMID 26659129 DOI: 10.1212/Wnl.0000000000002264 |
0.451 |
|
| 2015 |
Moreau A, Chahine M. [Omega pore, an alternative ion channel permeation pathway involved in the development of several channelopathies]. MéDecine Sciences : M/S. 31: 735-41. PMID 26340832 DOI: 10.1051/Medsci/20153108011 |
0.484 |
|
| 2015 |
Gosselin-Badaroudine P, Moreau A, Delemotte L, Cens T, Collet C, Rousset M, Charnet P, Klein ML, Chahine M. Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides. Scientific Reports. 5: 12475. PMID 26202396 DOI: 10.1038/Srep12475 |
0.492 |
|
| 2015 |
Thériault O, Poulin H, Beaulieu JM, Chahine M. Differential modulation of Nav1.7 and Nav1.8 channels by antidepressant drugs. European Journal of Pharmacology. 764: 395-403. PMID 26187311 DOI: 10.1016/J.Ejphar.2015.06.053 |
0.499 |
|
| 2015 |
O'Leary ME, Chahine M. MTSET modification of D4S6 cysteines stabilize the fast inactivated state of Nav1.5 sodium channels. Frontiers in Pharmacology. 6: 118. PMID 26150789 DOI: 10.3389/Fphar.2015.00118 |
0.601 |
|
| 2015 |
Moreau A, Gosselin-Badaroudine P, Chahine M. Gating pore currents, a new pathological mechanism underlying cardiac arrhythmias associated with dilated cardiomyopathy. Channels (Austin, Tex.). 9: 139-44. PMID 26046592 DOI: 10.1080/19336950.2015.1031937 |
0.478 |
|
| 2015 |
Chahine M. Gating pore current is a novel biophysical defect of Nav1.5 mutations associated with unusual cardiac arrhythmias and dilation. Future Cardiology. 11: 287-91. PMID 26021634 DOI: 10.2217/Fca.15.23 |
0.444 |
|
| 2015 |
Yue Y, Castrichini M, Srivastava U, Fabris F, Shah K, Li Z, Qu Y, El-Sherif N, Zhou Z, January C, Hussain MM, Jiang XC, Sobie EA, Wahren-Herlenius M, Chahine M, et al. Pathogenesis of the Novel Autoimmune-Associated Long QT Syndrome. Circulation. PMID 25995318 DOI: 10.1161/Circulationaha.115.009800 |
0.369 |
|
| 2015 |
Moreau A, Gosselin-Badaroudine P, Delemotte L, Klein ML, Chahine M. Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy. The Journal of General Physiology. 145: 93-106. PMID 25624448 DOI: 10.1085/Jgp.201411304 |
0.534 |
|
| 2015 |
Cens T, Rousset M, Collet C, Charreton M, Garnery L, Le Conte Y, Chahine M, Sandoz JC, Charnet P. Molecular characterization and functional expression of the Apis mellifera voltage-dependent Ca2+ channels. Insect Biochemistry and Molecular Biology. 58: 12-27. PMID 25602183 DOI: 10.1016/J.Ibmb.2015.01.005 |
0.471 |
|
| 2015 |
Pambrun T, Bortone A, Bois P, Degand B, Patri S, Mercier A, Chahine M, Chatelier A, Coisne D, Amiel A. Unmasked Brugada pattern by ajmaline challenge in patients with myotonic dystrophy type 1. Annals of Noninvasive Electrocardiology : the Official Journal of the International Society For Holter and Noninvasive Electrocardiology, Inc. 20: 28-36. PMID 24943134 DOI: 10.1111/Anec.12168 |
0.42 |
|
| 2015 |
Moreau A, Gosselin-Badaroudine P, Delemotte L, Klein ML, Chahine M. Gating Pore Currents are Common Defects of Two Nav1.5 Mutations in Patients with Mixed Arrhythmias and Dilated Cardiomyopathy Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.3131 |
0.498 |
|
| 2015 |
Habbout K, Guiliano S, Poulin H, Sternberg D, Eymard B, Rivier F, Juntas Morales R, Chahine M, Nicole S, Bendahhou S. Autosomal Recessive Inheritance of Congenital Myasthenic Syndrome is Associated with Skeletal Muscle Sodium Channel Mutations Biophysical Journal. 108: 491a. DOI: 10.1016/J.Bpj.2014.11.2684 |
0.498 |
|
| 2014 |
Kadala A, Charreton M, Jakob I, Cens T, Rousset M, Chahine M, Le Conte Y, Charnet P, Collet C. Pyrethroids differentially alter voltage-gated sodium channels from the honeybee central olfactory neurons. Plos One. 9: e112194. PMID 25390654 DOI: 10.1371/Journal.Pone.0112194 |
0.487 |
|
| 2014 |
Moreau A, Gosselin-Badaroudine P, Chahine M. Molecular biology and biophysical properties of ion channel gating pores. Quarterly Reviews of Biophysics. 47: 364-88. PMID 25382261 DOI: 10.1017/S0033583514000109 |
0.473 |
|
| 2014 |
Thériault O, Chahine M. Correlation of the electrophysiological profiles and sodium channel transcripts of individual rat dorsal root ganglia neurons. Frontiers in Cellular Neuroscience. 8: 285. PMID 25285069 DOI: 10.3389/Fncel.2014.00285 |
0.489 |
|
| 2014 |
Poulin H, Bruhova I, Timour Q, Theriault O, Beaulieu JM, Frassati D, Chahine M. Fluoxetine blocks Nav1.5 channels via a mechanism similar to that of class 1 antiarrhythmics. Molecular Pharmacology. 86: 378-89. PMID 25028482 DOI: 10.1016/J.Bpj.2013.11.1874 |
0.543 |
|
| 2014 |
Moreau A, Gosselin-Badaroudine P, Chahine M. Biophysics, pathophysiology, and pharmacology of ion channel gating pores. Frontiers in Pharmacology. 5: 53. PMID 24772081 DOI: 10.3389/Fphar.2014.00053 |
0.544 |
|
| 2014 |
Pambrun T, Mercier A, Chatelier A, Patri S, Schott JJ, Le Scouarnec S, Chahine M, Degand B, Bois P. Myotonic dystrophy type 1 mimics and exacerbates Brugada phenotype induced by Nav1.5 sodium channel loss-of-function mutation. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 11: 1393-400. PMID 24768612 DOI: 10.1016/J.Hrthm.2014.04.026 |
0.44 |
|
| 2014 |
Chahine M, O'Leary ME. Regulation/modulation of sensory neuron sodium channels. Handbook of Experimental Pharmacology. 221: 111-35. PMID 24737234 DOI: 10.1007/978-3-642-41588-3_6 |
0.495 |
|
| 2014 |
Thériault O, Poulin H, Thomas GR, Friesen AD, Al-Shaqha WA, Chahine M. Pyridoxal-5'-phosphate (MC-1), a vitamin B6 derivative, inhibits expressed P2X receptors. Canadian Journal of Physiology and Pharmacology. 92: 189-96. PMID 24593783 DOI: 10.1139/Cjpp-2013-0404 |
0.309 |
|
| 2014 |
Thériault O, Poulin H, Sculptoreanu A, de Groat WC, O'Leary ME, Chahine M. Modulation of peripheral Na(+) channels and neuronal firing by n-butyl-p-aminobenzoate. European Journal of Pharmacology. 727: 158-66. PMID 24486399 DOI: 10.1016/J.Ejphar.2014.01.036 |
0.516 |
|
| 2014 |
Mechakra A, Vincent Y, Chevalier P, Millat G, Ficker E, Jastrzebski M, Poulin H, Pouliot V, Chahine M, Christé G. The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT. Gene. 536: 348-56. PMID 24334129 DOI: 10.1016/J.Gene.2013.11.072 |
0.396 |
|
| 2014 |
Gosselin-Badaroudine P, Moreau A, Chahine M. Nav 1.5 mutations linked to dilated cardiomyopathy phenotypes: Is the gating pore current the missing link? Channels (Austin, Tex.). 8: 90-4. PMID 24300601 DOI: 10.4161/Chan.27179 |
0.454 |
|
| 2013 |
Moreau A, Krahn AD, Gosselin-Badaroudine P, Klein GJ, Christé G, Vincent Y, Boutjdir M, Chahine M. Sodium overload due to a persistent current that attenuates the arrhythmogenic potential of a novel LQT3 mutation. Frontiers in Pharmacology. 4: 126. PMID 24098284 DOI: 10.3389/Fphar.2013.00126 |
0.476 |
|
| 2013 |
Desaphy JF, Chahine M. Recent advances in voltage-gated sodium channels, their pharmacology, and related diseases. Frontiers in Pharmacology. 4: 52. PMID 23616770 DOI: 10.3389/Fphar.2013.00052 |
0.541 |
|
| 2013 |
Maury P, Moreau A, Hidden-Lucet F, Leenhardt A, Fressart V, Berthet M, Denjoy I, Bennamar N, Rollin A, Cardin C, Guicheney P, Chahine M. Novel SCN5A mutations in two families with "Brugada-like" ST elevation in the inferior leads and conduction disturbances. Journal of Interventional Cardiac Electrophysiology : An International Journal of Arrhythmias and Pacing. 37: 131-40. PMID 23612926 DOI: 10.1007/S10840-013-9805-7 |
0.447 |
|
| 2013 |
Cens T, Rousset M, Collet C, Raymond V, Démares F, Quintavalle A, Bellis M, Le Conte Y, Chahine M, Charnet P. Characterization of the first honeybee Ca²⺠channel subunit reveals two novel species- and splicing-specific modes of regulation of channel inactivation. Pflã¼Gers Archiv : European Journal of Physiology. 465: 985-96. PMID 23588376 DOI: 10.1007/S00424-013-1223-2 |
0.525 |
|
| 2013 |
Theriault O, Chahine M. Correlation of Sodium Channels Transcripts of Single DRG Neuron to their Electrophysiological and Pharmacological Profiles Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.764 |
0.383 |
|
| 2013 |
Gosselin-Badaroudine P, Delemotte L, Moreau A, Klein ML, Chahine M. Investigating the Voltage Sensor Domains of Nav1.4, its Structural and Functional Properties via Histidine Scanning Mutagenesis Biophysical Journal. 104: 133a. DOI: 10.1016/J.Bpj.2012.11.759 |
0.436 |
|
| 2013 |
Moreau A, Gosselin-Badaroudine P, Poulin H, Chahine M. Development and Characterisation of Cardiomyocytes Derived from Murine Embryonic Stem Cells of a DCM Caused by a SCN5A Mutation Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.111 |
0.503 |
|
| 2012 |
Gosselin-Badaroudine P, Delemotte L, Moreau A, Klein ML, Chahine M. Gating pore currents and the resting state of Nav1.4 voltage sensor domains Proceedings of the National Academy of Sciences of the United States of America. 109: 19250-19255. PMID 23134726 DOI: 10.1073/Pnas.1217990109 |
0.543 |
|
| 2012 |
Mercier A, Clément R, Harnois T, Bourmeyster N, Faivre JF, Findlay I, Chahine M, Bois P, Chatelier A. The β1-subunit of Na(v)1.5 cardiac sodium channel is required for a dominant negative effect through α-α interaction. Plos One. 7: e48690. PMID 23133651 DOI: 10.1371/Journal.Pone.0048690 |
0.545 |
|
| 2012 |
Chatelier A, Mercier A, Tremblier B, Thériault O, Moubarak M, Benamer N, Corbi P, Bois P, Chahine M, Faivre JF. A distinct de novo expression of Nav1.5 sodium channels in human atrial fibroblasts differentiated into myofibroblasts. The Journal of Physiology. 590: 4307-19. PMID 22802584 DOI: 10.1113/Jphysiol.2012.233593 |
0.533 |
|
| 2012 |
Gosselin-Badaroudine P, Keller DI, Huang H, Pouliot V, Chatelier A, Osswald S, Brink M, Chahine M. A proton leak current through the cardiac sodium channel is linked to mixed arrhythmia and the dilated cardiomyopathy phenotype. Plos One. 7: e38331. PMID 22675453 DOI: 10.1371/Journal.Pone.0038331 |
0.55 |
|
| 2012 |
Moreau A, Keller DI, Huang H, Fressart V, Schmied C, Timour Q, Chahine M. Mexiletine differentially restores the trafficking defects caused by two brugada syndrome mutations. Frontiers in Pharmacology. 3: 62. PMID 22529811 DOI: 10.3389/Fphar.2012.00062 |
0.589 |
|
| 2012 |
Ho C, Zhao J, Malinowski S, Chahine M, O'Leary ME. Differential expression of sodium channel β subunits in dorsal root ganglion sensory neurons. The Journal of Biological Chemistry. 287: 15044-53. PMID 22408255 DOI: 10.1074/Jbc.M111.333740 |
0.381 |
|
| 2012 |
Zhao J, Duprè N, Puymirat J, Chahine M. Biophysical characterization of M1476I, a sodium channel founder mutation associated with cold-induced myotonia in French Canadians. The Journal of Physiology. 590: 2629-44. PMID 22250216 DOI: 10.1113/Jphysiol.2011.223461 |
0.583 |
|
| 2012 |
Gosselin-Badaroudine P, Keller DI, Huang H, Chatelier A, Chahine M. A Proton Leak Current through the Cardiac Sodium Channel Linked to Mixed Arrhythmia and Dilated Cardiomyopathy Phenotypes Biophysical Journal. 102: 5-6. DOI: 10.1016/J.Bpj.2011.11.2877 |
0.554 |
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| 2011 |
Chahine M, O'Leary ME. Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons. Frontiers in Pharmacology. 2: 70. PMID 22125538 DOI: 10.3389/Fphar.2011.00070 |
0.468 |
|
| 2011 |
Chahine M. New insights into cardiac and brain sodium channels modulation by Beta blockers. Frontiers in Pharmacology. 2: 1. PMID 21779246 DOI: 10.3389/Fphar.2011.00001 |
0.513 |
|
| 2011 |
Zhao J, O'Leary ME, Chahine M. Regulation of Nav1.6 and Nav1.8 peripheral nerve Na+ channels by auxiliary β-subunits. Journal of Neurophysiology. 106: 608-19. PMID 21562192 DOI: 10.1152/Jn.00107.2011 |
0.456 |
|
| 2011 |
Qu Y, Karnabi E, Ramadan O, Yue Y, Chahine M, Boutjdir M. Perinatal and postnatal expression of Cav1.3 α1D Ca²⁺ channel in the rat heart. Pediatric Research. 69: 479-84. PMID 21378599 DOI: 10.1203/Pdr.0B013E318217A0Df |
0.521 |
|
| 2011 |
Huang H, Priori SG, Napolitano C, O'Leary ME, Chahine M. Y1767C, a novel SCN5A mutation, induces a persistent Na+ current and potentiates ranolazine inhibition of Nav1.5 channels. American Journal of Physiology. Heart and Circulatory Physiology. 300: H288-99. PMID 21076026 DOI: 10.1152/Ajpheart.00539.2010 |
0.598 |
|
| 2011 |
Huang H, Priori SG, Napolitano C, O’Leary ME, Chahine M. Y1767C, a Novel SCN5A Mutation Induces a Persistent Sodium Current and Potentiates Ranolazine Inhibition of NaV1.5 Channels Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.2494 |
0.6 |
|
| 2010 |
Chatelier A, Zhao J, Bois P, Chahine M. Biophysical characterisation of the persistent sodium current of the Nav1.6 neuronal sodium channel: a single-channel analysis. PflüGers Archiv : European Journal of Physiology. 460: 77-86. PMID 20204400 DOI: 10.1007/S00424-010-0801-9 |
0.551 |
|
| 2010 |
Ziane R, Huang H, Moghadaszadeh B, Beggs AH, Levesque G, Chahine M. Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction. Biochemistry. 49: 166-78. PMID 19943616 DOI: 10.1021/Bi901086V |
0.491 |
|
| 2010 |
Karnabi E, Qu Y, Wadgaonkar R, Mancarella S, Yue Y, Chahine M, Clancy RM, Buyon JP, Boutjdir M. Congenital heart block: identification of autoantibody binding site on the extracellular loop (domain I, S5-S6) of alpha(1D) L-type Ca channel. Journal of Autoimmunity. 34: 80-6. PMID 19640679 DOI: 10.1016/J.Jaut.2009.06.005 |
0.332 |
|
| 2009 |
Chahine M. Cardiac metabolic state and Brugada syndrome: a link revealed. Circulation Research. 105: 721-3. PMID 19815826 DOI: 10.1161/Circresaha.109.208405 |
0.536 |
|
| 2009 |
Keller DI, Grenier J, Christé G, Dubouloz F, Osswald S, Brink M, Ficker E, Chahine M. Characterization of novel KCNH2 mutations in type 2 long QT syndrome manifesting as seizures. The Canadian Journal of Cardiology. 25: 455-62. PMID 19668779 DOI: 10.1016/S0828-282X(09)70117-5 |
0.43 |
|
| 2009 |
Huang H, Millat G, Rodriguez-Lafrasse C, Rousson R, Kugener B, Chevalier P, Chahine M. Biophysical characterization of a new SCN5A mutation S1333Y in a SIDS infant linked to long QT syndrome. Febs Letters. 583: 890-6. PMID 19302788 DOI: 10.1016/J.Febslet.2009.02.007 |
0.463 |
|
| 2009 |
Li Q, Huang H, Liu G, Lam K, Rutberg J, Green MS, Birnie DH, Lemery R, Chahine M, Gollob MH. Gain-of-function mutation of Nav1.5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing. Biochemical and Biophysical Research Communications. 380: 132-7. PMID 19167345 DOI: 10.1016/J.Bbrc.2009.01.052 |
0.481 |
|
| 2009 |
Ramadan O, Qu Y, Wadgaonkar R, Baroudi G, Karnabi E, Chahine M, Boutjdir M. Phosphorylation of the consensus sites of protein kinase A on alpha1D L-type calcium channel. The Journal of Biological Chemistry. 284: 5042-9. PMID 19074150 DOI: 10.1074/Jbc.M809132200 |
0.421 |
|
| 2008 |
Christé G, Thériault O, Chahine M, Millat G, Rodriguez-Lafrasse C, Rousson R, Deschênes I, Ficker E, Chevalier P. A new C-terminal hERG mutation A915fs+47X associated with symptomatic LQT2 and auditory-trigger syncope. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 5: 1577-86. PMID 18984536 DOI: 10.1016/J.Hrthm.2008.08.031 |
0.594 |
|
| 2008 |
Lin MT, Wu MH, Chang CC, Chiu SN, Thériault O, Huang H, Christé G, Ficker E, Chahine M. In utero onset of long QT syndrome with atrioventricular block and spontaneous or lidocaine-induced ventricular tachycardia: compound effects of hERG pore region mutation and SCN5A N-terminus variant. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 5: 1567-74. PMID 18848812 DOI: 10.1016/J.Hrthm.2008.08.010 |
0.338 |
|
| 2008 |
Chahine M, Chatelier A, Babich O, Krupp JJ. Voltage-gated sodium channels in neurological disorders. Cns & Neurological Disorders Drug Targets. 7: 144-58. PMID 18537643 DOI: 10.2174/187152708784083830 |
0.561 |
|
| 2008 |
Hossain MI, Iwasaki H, Okochi Y, Chahine M, Higashijima S, Nagayama K, Okamura Y. Enzyme domain affects the movement of the voltage sensor in ascidian and zebrafish voltage-sensing phosphatases. The Journal of Biological Chemistry. 283: 18248-59. PMID 18375390 DOI: 10.1074/Jbc.M706184200 |
0.409 |
|
| 2008 |
Chatelier A, Dahllund L, Eriksson A, Krupp J, Chahine M. Biophysical properties of human Na v1.7 splice variants and their regulation by protein kinase A. Journal of Neurophysiology. 99: 2241-50. PMID 18337362 DOI: 10.1152/Jn.01350.2007 |
0.482 |
|
| 2008 |
Six I, Hermida JS, Huang H, Gouas L, Fressart V, Benammar N, Hainque B, Denjoy I, Chahine M, Guicheney P. The occurrence of Brugada syndrome and isolated cardiac conductive disease in the same family could be due to a single SCN5A mutation or to the accidental association of both diseases. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 10: 79-85. PMID 18156160 DOI: 10.1093/Europace/Eum271 |
0.343 |
|
| 2008 |
Chahine M, Qu Y, Mancarella S, Boutjdir M. Protein kinase C activation inhibits α1D L-type Ca channel: A single-channel analysis Pflugers Archiv European Journal of Physiology. 455: 913-919. PMID 17909852 DOI: 10.1007/S00424-007-0342-Z |
0.513 |
|
| 2008 |
Christé G, Chahine M, Chevalier P, Pásek M. Changes in action potentials and intracellular ionic homeostasis in a ventricular cell model related to a persistent sodium current in SCN5A mutations underlying LQT3 Progress in Biophysics and Molecular Biology. 96: 281-293. PMID 17892895 DOI: 10.1016/J.Pbiomolbio.2007.07.023 |
0.377 |
|
| 2007 |
Blanchet J, Chahine M. Accessibility of four arginine residues on the S4 segment of the Bacillus halodurans sodium channel. The Journal of Membrane Biology. 215: 169-80. PMID 17568977 DOI: 10.1007/S00232-007-9016-1 |
0.4 |
|
| 2007 |
Zhao J, Ziane R, Chatelier A, O'leary ME, Chahine M. Lidocaine promotes the trafficking and functional expression of Na(v)1.8 sodium channels in mammalian cells. Journal of Neurophysiology. 98: 467-77. PMID 17507497 DOI: 10.1152/Jn.00117.2007 |
0.556 |
|
| 2007 |
Blanchet J, Pilote S, Chahine M. Acidic residues on the voltage-sensor domain determine the activation of the NaChBac sodium channel. Biophysical Journal. 92: 3513-23. PMID 17325004 DOI: 10.1529/Biophysj.106.090464 |
0.354 |
|
| 2007 |
Qu Y, Karnabi E, Chahine M, Vassalle M, Boutjdir M. Expression of skeletal muscle Na(V)1.4 Na channel isoform in canine cardiac Purkinje myocytes. Biochemical and Biophysical Research Communications. 355: 28-33. PMID 17286959 DOI: 10.1016/J.Bbrc.2007.01.101 |
0.455 |
|
| 2007 |
Shin DJ, Kim E, Park SB, Jang WC, Bae Y, Han J, Jang Y, Joung B, Lee MH, Kim SS, Huang H, Chahine M, Yoon SK. A novel mutation in the SCN5A gene is associated with Brugada syndrome. Life Sciences. 80: 716-24. PMID 17141278 DOI: 10.1016/J.Lfs.2006.10.025 |
0.599 |
|
| 2006 |
Herbert E, Chahine M. Clinical aspects and physiopathology of Brugada syndrome: review of current concepts. Canadian Journal of Physiology and Pharmacology. 84: 795-802. PMID 17111025 DOI: 10.1139/Y06-038 |
0.451 |
|
| 2006 |
Baroudi G, Qu Y, Ramadan O, Chahine M, Boutjdir M. Protein kinase C activation inhibits Cav1.3 calcium channel at NH2-terminal serine 81 phosphorylation site. American Journal of Physiology. Heart and Circulatory Physiology. 291: H1614-22. PMID 16973824 DOI: 10.1152/Ajpheart.00095.2006 |
0.415 |
|
| 2006 |
Poelzing S, Forleo C, Samodell M, Dudash L, Sorrentino S, Anaclerio M, Troccoli R, Iacoviello M, Romito R, Guida P, Chahine M, Pitzalis M, Deschênes I. SCN5A polymorphism restores trafficking of a Brugada syndrome mutation on a separate gene. Circulation. 114: 368-76. PMID 16864729 DOI: 10.1161/Circulationaha.105.601294 |
0.677 |
|
| 2006 |
Keller DI, Huang H, Zhao J, Frank R, Suarez V, Delacrétaz E, Brink M, Osswald S, Schwick N, Chahine M. A novel SCN5A mutation, F1344S, identified in a patient with Brugada syndrome and fever-induced ventricular fibrillation. Cardiovascular Research. 70: 521-9. PMID 16616735 DOI: 10.1016/J.Cardiores.2006.02.030 |
0.438 |
|
| 2006 |
Huang H, Zhao J, Barrane FZ, Champagne J, Chahine M. Nav1.5/R1193Q polymorphism is associated with both long QT and Brugada syndromes. The Canadian Journal of Cardiology. 22: 309-13. PMID 16568155 DOI: 10.1016/S0828-282X(06)70915-1 |
0.317 |
|
| 2005 |
Chahine M, Ziane R, Vijayaragavan K, Okamura Y. Regulation of Na v channels in sensory neurons. Trends in Pharmacological Sciences. 26: 496-502. PMID 16125256 DOI: 10.1016/J.Tips.2005.08.002 |
0.796 |
|
| 2004 |
Chahine M, Pilote S, Pouliot V, Takami H, Sato C. Role of arginine residues on the S4 segment of the Bacillus halodurans Na+ channel in voltage-sensing. The Journal of Membrane Biology. 201: 9-24. PMID 15635808 DOI: 10.1007/S00232-004-0701-Z |
0.495 |
|
| 2004 |
Chang CC, Acharfi S, Wu MH, Chiang FT, Wang JK, Sung TC, Chahine M. A novel SCN5A mutation manifests as a malignant form of long QT syndrome with perinatal onset of tachycardia/bradycardia. Cardiovascular Research. 64: 268-78. PMID 15485686 DOI: 10.1016/J.Cardiores.2004.07.007 |
0.313 |
|
| 2004 |
Shin DJ, Jang Y, Park HY, Lee JE, Yang K, Kim E, Bae Y, Kim J, Kim J, Kim SS, Lee MH, Chahine M, Yoon SK. Genetic analysis of the cardiac sodium channel gene SCN5A in Koreans with Brugada syndrome. Journal of Human Genetics. 49: 573-8. PMID 15338453 DOI: 10.1007/S10038-004-0182-Z |
0.444 |
|
| 2004 |
Vijayaragavan K, Powell AJ, Kinghorn IJ, Chahine M. Role of auxiliary beta1-, beta2-, and beta3-subunits and their interaction with Na(v)1.8 voltage-gated sodium channel. Biochemical and Biophysical Research Communications. 319: 531-40. PMID 15178439 DOI: 10.1016/J.Bbrc.2004.05.026 |
0.739 |
|
| 2004 |
Chevrier P, Vijayaragavan K, Chahine M. Differential modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by the local anesthetic lidocaine. British Journal of Pharmacology. 142: 576-84. PMID 15148257 DOI: 10.1038/Sj.Bjp.0705796 |
0.811 |
|
| 2004 |
Baroudi G, Napolitano C, Priori SG, Del Bufalo A, Chahine M. Loss of function associated with novel mutations of the SCN5A gene in patients with Brugada syndrome. The Canadian Journal of Cardiology. 20: 425-30. PMID 15057319 |
0.352 |
|
| 2004 |
Vijayaragavan K, Acharfi S, Chahine M. The C-terminal region as a modulator of rNa(v)1.7 and rNa(v)1.8 expression levels. Febs Letters. 559: 39-44. PMID 14960304 DOI: 10.1016/S0014-5793(04)00019-5 |
0.74 |
|
| 2004 |
Vijayaragavan K, Boutjdir M, Chahine M. Modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by protein kinase A and protein kinase C. Journal of Neurophysiology. 91: 1556-69. PMID 14657190 DOI: 10.1152/Jn.00676.2003 |
0.794 |
|
| 2003 |
Keller DI, Acharfi S, Delacrétaz E, Benammar N, Rotter M, Pfammatter JP, Fressart V, Guicheney P, Chahine M. A novel mutation in SCN5A, delQKP 1507-1509, causing long QT syndrome: role of Q1507 residue in sodium channel inactivation. Journal of Molecular and Cellular Cardiology. 35: 1513-21. PMID 14654377 DOI: 10.1016/J.Yjmcc.2003.08.007 |
0.6 |
|
| 2003 |
O'Leary ME, Digregorio M, Chahine M. Closing and inactivation potentiate the cocaethylene inhibition of cardiac sodium channels by distinct mechanisms. Molecular Pharmacology. 64: 1575-1585. PMID 14645689 DOI: 10.1124/Mol.64.6.1575 |
0.568 |
|
| 2003 |
Mok NS, Priori SG, Napolitano C, Chan NY, Chahine M, Baroudi G. A newly characterized SCN5A mutation underlying Brugada syndrome unmasked by hyperthermia. Journal of Cardiovascular Electrophysiology. 14: 407-11. PMID 12741714 DOI: 10.1046/J.1540-8167.2003.02379.X |
0.366 |
|
| 2003 |
Chahine M, Sculptoreanu A, Varma DR. Modulation of L-type Ca2+ channels in neonatal rat heart by a novel Ca2+ channel agonist. Canadian Journal of Physiology and Pharmacology. 81: 135-41. PMID 12710527 DOI: 10.1139/Y02-161 |
0.411 |
|
| 2003 |
Deschênes D, Acharfi S, Pouliot V, Hegele R, Krahn A, Daleau P, Chahine M. Biophysical characteristics of a new mutation on the KCNQ1 potassium channel (L251P) causing long QT syndrome. Canadian Journal of Physiology and Pharmacology. 81: 129-34. PMID 12710526 DOI: 10.1139/Y02-162 |
0.531 |
|
| 2002 |
Carbonneau E, Vijayaragavan K, Chahine M. A tryptophan residue (W736) in the amino-terminus of the P-segment of domain II is involved in pore formation in Na(v)1.4 voltage-gated sodium channels. PflüGers Archiv : European Journal of Physiology. 445: 18-24. PMID 12397382 DOI: 10.1007/S00424-002-0887-9 |
0.803 |
|
| 2002 |
O'Leary ME, Chahine M. Cocaine binds to a common site on open and inactivated human heart (Nav1.5) sodium channels The Journal of Physiology. 541: 701-716. PMID 12068034 DOI: 10.1113/Jphysiol.2001.016139 |
0.472 |
|
| 2002 |
Baroudi G, Acharfi S, Larouche C, Chahine M. Expression and intracellular localization of an SCN5A double mutant R1232W/T1620M implicated in Brugada syndrome. Circulation Research. 90: E11-6. PMID 11786529 DOI: 10.1161/Hh0102.102977 |
0.538 |
|
| 2001 |
Vijayaragavan K, O'Leary ME, Chahine M. Gating properties of Na(v)1.7 and Na(v)1.8 peripheral nerve sodium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7909-18. PMID 11588164 DOI: 10.1523/Jneurosci.21-20-07909.2001 |
0.792 |
|
| 2001 |
Deschênes I, Trottier E, Chahine M. Implication of the C-terminal region of the alpha-subunit of voltage-gated sodium channels in fast inactivation. The Journal of Membrane Biology. 183: 103-14. PMID 11562792 DOI: 10.1007/S00232-001-0058-5 |
0.739 |
|
| 2001 |
Lupoglazoff JM, Cheav T, Baroudi G, Berthet M, Denjoy I, Cauchemez B, Extramiana F, Chahine M, Guicheney P. Homozygous SCN5A Mutation in Long-QT Syndrome With Functional Two-to-One Atrioventricular Block Circulation Research. 89. PMID 11463728 DOI: 10.1161/Hh1401.095087 |
0.445 |
|
| 2001 |
Baroudi G, Pouliot V, Denjoy I, Guicheney P, Shrier A, Chahine M. Novel mechanism for Brugada syndrome: defective surface localization of an SCN5A mutant (R1432G). Circulation Research. 88: E78-83. PMID 11420310 DOI: 10.1161/Hh1201.093270 |
0.482 |
|
| 2000 |
Baroudi G, Chahine M. Biophysical phenotypes of SCN5A mutations causing long QT and Brugada syndromes. Febs Letters. 487: 224-228. PMID 11150514 DOI: 10.1016/S0014-5793(00)02360-7 |
0.538 |
|
| 2000 |
Deschênes I, Baroudi G, Berthet M, Barde I, Chalvidan T, Denjoy I, Guicheney P, Chahine M. Electrophysiological characterization of SCN5A mutations causing long QT (E1784K) and Brugada (R1512W and R1432G) syndromes. Cardiovascular Research. 46: 55-65. PMID 10727653 DOI: 10.1016/S0008-6363(00)00006-7 |
0.617 |
|
| 2000 |
Baroudi G, Carbonneau E, Pouliot V, Chahine M. SCN5A mutation (T1620M) causing Brugada syndrome exhibits different phenotypes when expressed in Xenopus oocytes and mammalian cells. Febs Letters. 467: 12-16. PMID 10664447 DOI: 10.1016/S0014-5793(00)01099-1 |
0.519 |
|
| 1999 |
Deschênes I, Trottier E, Chahine M. Cysteine scanning analysis of the IFM cluster in the inactivation gate of a human heart sodium channel. Cardiovascular Research. 42: 521-9. PMID 10533587 DOI: 10.1016/S0008-6363(99)00064-4 |
0.728 |
|
| 1999 |
Bérubé J, Chahine M, Daleau P. Modulation of HERG potassium channel properties by external pH PflüGers Archiv: European Journal of Physiology. 438: 419-422. PMID 10398876 DOI: 10.1007/S004240050930 |
0.524 |
|
| 1998 |
Chahine M, Sirois J, Marcotte P, Chen LQ, Kallen RG. Extrapore residues of the S5-S6 loop of domain 2 of the voltage-gated skeletal muscle sodium channel (rSkM1) contribute to the μ-conotoxin GIIIA binding site Biophysical Journal. 75: 236-246. PMID 9649383 DOI: 10.1016/S0006-3495(98)77510-1 |
0.359 |
|
| 1998 |
Deschênes I, Chen L, Kallen RG, Chahine M. Electrophysiological study of chimeric sodium channels from heart and skeletal muscle. The Journal of Membrane Biology. 164: 25-34. PMID 9636241 DOI: 10.1007/S002329900390 |
0.721 |
|
| 1997 |
Chahine M, George AL. Myotonic Dystrophy Kinase Modulates Skeletal Muscle But Not Cardiac Voltage-Gated Sodium Channels Febs Letters. 412: 621-624. PMID 9276478 DOI: 10.1016/S0014-5793(97)00869-7 |
0.528 |
|
| 1997 |
Chahine M, Deschênes I, Trottier E, Chen LQ, Kallen RG. Restoration of fast inactivation in an inactivation-defective human heart sodium channel by the cysteine modifying reagent benzyl-MTS: analysis of IFM-ICM mutation. Biochemical and Biophysical Research Communications. 233: 606-10. PMID 9168898 DOI: 10.1006/Bbrc.1997.6510 |
0.755 |
|
| 1997 |
Deschênes I, Chahine M, Tremblay J, Paulin D, Puymirat J. Increase in the proliferative capacity of human myoblasts by using the T antigen under the vimentin promoter control. Muscle & Nerve. 20: 437-45. PMID 9121501 DOI: 10.1002/(Sici)1097-4598(199704)20:4<437::Aid-Mus6>3.0.Co;2-B |
0.58 |
|
| 1997 |
Marcotte P, Chen LQ, Kallen RG, Chahine M. Effects of Tityus serrulatus scorpion toxin gamma on voltage-gated Na+ channels. Circulation Research. 80: 363-9. PMID 9048656 DOI: 10.1161/01.Res.80.3.363 |
0.418 |
|
| 1994 |
Chahine M, George AL, Zhou M, Ji S, Sun W, Barchi RL, Horn R. Sodium channel mutations in paramyotonia congenita uncouple inactivation from activation. Neuron. 12: 281-94. PMID 8110459 DOI: 10.1016/0896-6273(94)90271-2 |
0.576 |
|
| 1994 |
Chahine M, Bennett PB, George AL, Horn R. Functional expression and properties of the human skeletal muscle sodium channel. Pflã¼Gers Archiv : European Journal of Physiology. 427: 136-42. PMID 8058462 DOI: 10.1007/Bf00585952 |
0.522 |
|
| 1992 |
Chahine M, Chen LQ, Barchi RL, Kallen RG, Horn R. Lidocaine block of human heart sodium channels expressed in Xenopus oocytes. Journal of Molecular and Cellular Cardiology. 24: 1231-6. PMID 1336062 DOI: 10.1016/0022-2828(92)93090-7 |
0.477 |
|
| 1992 |
Chen LQ, Chahine M, Kallen RG, Barchi RL, Horn R. Chimeric study of sodium channels from rat skeletal and cardiac muscle. Febs Letters. 309: 253-7. PMID 1325372 DOI: 10.1016/0014-5793(92)80783-D |
0.518 |
|
| 1992 |
Chahine M, Chen LQ, Kallen RG, Barchi RL, Horn R. Expressed Na channel clones differ in their sensitivity to external calcium concentration. Biophysical Journal. 62: 37-40. PMID 1318104 DOI: 10.1016/S0006-3495(92)81771-X |
0.459 |
|
| 1992 |
Gellens ME, George AL, Chen LQ, Chahine M, Horn R, Barchi RL, Kallen RG. Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel. Proceedings of the National Academy of Sciences of the United States of America. 89: 554-8. PMID 1309946 DOI: 10.1073/Pnas.89.2.554 |
0.539 |
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