| Year |
Citation |
Score |
| 2024 |
Chinthalapudi K, Biswas R, López-Serrano A, Huang HL, Ramirez-Navarro A, Grandinetti G, Heissler S, Deschênes I. Structural basis of human Na1.5 gating mechanisms. Research Square. PMID 38659812 DOI: 10.21203/rs.3.rs-3985999/v1 |
0.377 |
|
| 2024 |
Deschênes I, Biswas R, Chinthalapudi K. Advances in understanding of cardiac sodium channel structure/function and their relation to disease pathogenesis and treatment. Heart Rhythm. 21: 124-125. PMID 38176766 DOI: 10.1016/j.hrthm.2023.11.004 |
0.357 |
|
| 2023 |
Loyo-Celis V, Patel D, Sanghvi S, Kaur K, Ponnalagu D, Zheng Y, Bindra S, Bhachu HR, Deschenes I, Gururaja Rao S, Singh H. Biophysical Characterization of Chloride Intracellular Channel 6 (CLIC6). The Journal of Biological Chemistry. 105349. PMID 37838179 DOI: 10.1016/j.jbc.2023.105349 |
0.327 |
|
| 2022 |
Zheng Y, Deschenes I. Protein 14-3-3 Influences the Response of the Cardiac Sodium Channel Na1.5 to Anti-Arrhythmic Drugs. The Journal of Pharmacology and Experimental Therapeutics. PMID 36460339 DOI: 10.1124/jpet.122.001407 |
0.508 |
|
| 2022 |
Clatot J, Coulombe A, Deschênes I, Guicheney P, Neyroud N. Trafficking and Gating Cooperation Between Deficient Na1.5-mutant Channels to Rescue I. Frontiers in Bioscience (Landmark Edition). 27: 209. PMID 35866404 DOI: 10.31083/j.fbl2707209 |
0.497 |
|
| 2021 |
Zheng Y, Wan X, Yang D, Ramirez-Navarro A, Liu H, Fu JD, Deschênes I. A Heart Failure-Associated Splice Variant Leads to a Reduction in Sodium Current Through Coupled-Gating With the Wild-Type Channel. Frontiers in Physiology. 12: 661429. PMID 33828490 DOI: 10.3389/fphys.2021.661429 |
0.606 |
|
| 2021 |
Hu RM, Song EJ, Tester DJ, Deschenes I, Ackerman MJ, Makielski JC, Tan BH. Expression defect of the rare variant/Brugada mutation R1512W depends upon the SCN5A splice variant background and can be rescued by mexiletine and the common polymorphism H558R. Channels (Austin, Tex.). 15: 253-261. PMID 33535892 DOI: 10.1080/19336950.2021.1875645 |
0.391 |
|
| 2021 |
Poulin H, Mercier A, Djemai M, Pouliot V, Deschenes I, Boutjdir M, Puymirat J, Chahine M. iPSC-derived cardiomyocytes from patients with myotonic dystrophy type 1 have abnormal ion channel functions and slower conduction velocities. Scientific Reports. 11: 2500. PMID 33510259 DOI: 10.1038/s41598-021-82007-8 |
0.618 |
|
| 2021 |
Zheng Y, Wan X, Yang D, Ramirez-Navarro A, Liu H, Fu J, Deschênes I. A Heart Failure-Associated SCN5A Splice Variant Leads to a Reduction in Sodium Current Through Coupled-Gating With the Wild-Type Channel Frontiers in Physiology. 12. DOI: 10.3389/fphys.2021.661429 |
0.473 |
|
| 2020 |
Nowak MB, Greer-Short A, Wan X, Wu X, Deschênes I, Weinberg SH, Poelzing S. Intercellular Sodium Regulates Repolarization in Cardiac Tissue with Sodium Channel Gain of Function. Biophysical Journal. PMID 32402243 DOI: 10.1016/J.Bpj.2020.04.014 |
0.537 |
|
| 2020 |
Zheng Y, Liu H, Wan X, Deschenes I. An SCN5A Splice Variant Associated with Heart Failure Leads to a Reduction in Sodium Current Through Coupled Gating with the WT Channel Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.3136 |
0.475 |
|
| 2020 |
Miles M, Rodriguez N, Jiang M, Tomaszewski JE, Deschenes I, Tseng G. Cardiac Palmitome Sheds New Light on the Structural and Functional Roles of S-Palmitoylation in Cardiac Myocytes Biophysical Journal. 118: 257a. DOI: 10.1016/J.Bpj.2019.11.1495 |
0.337 |
|
| 2019 |
Murthy A, Workman S, Jiang M, Hu J, Sifa I, Bernas T, Tang W, Deschenes I, Tseng GN. Dynamic palmitoylation regulates trafficking of K channel interacting protein 2 (KChIP2) across multiple subcellular compartments in cardiac myocytes. Journal of Molecular and Cellular Cardiology. PMID 31362018 DOI: 10.1016/J.Yjmcc.2019.07.013 |
0.466 |
|
| 2018 |
Li J, Gresham KS, Mamidi R, Doh CY, Wan X, Deschenes I, Stelzer JE. Sarcomere-based genetic enhancement of systolic cardiac function in a murine model of dilated cardiomyopathy. International Journal of Cardiology. PMID 30279005 DOI: 10.1016/J.Ijcard.2018.09.073 |
0.347 |
|
| 2018 |
Clatot J, Zheng Y, Girardeau A, Liu H, Laurita KR, Marionneau C, Deschenes I. Mutant voltage-gated sodium channels can exert a dominant-negative effect through coupled gating. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30118344 DOI: 10.1152/Ajpheart.00721.2017 |
0.63 |
|
| 2018 |
Veeraraghavan R, Hoeker GS, Alvarez-Laviada A, Hoagland D, Wan X, King DR, Sanchez-Alonso J, Chen C, Jourdan J, Isom LL, Deschenes I, Smyth J, Gorelik J, Poelzing S, Gourdie RG. The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation. Elife. 7. PMID 30106376 DOI: 10.7554/Elife.37610 |
0.406 |
|
| 2018 |
Chatterjee S, Vyas R, Chalamalasetti SV, Sahu ID, Clatot J, Wan X, Lorigan GA, Deschênes I, Chakrapani S. The voltage-gated sodium channel pore exhibits conformational flexibility during slow inactivation. The Journal of General Physiology. PMID 30082431 DOI: 10.1085/Jgp.201812118 |
0.476 |
|
| 2018 |
Staudacher I, Illg C, Chai S, Deschenes I, Seehausen S, Gramlich D, Müller ME, Wieder T, Rahm AK, Mayer C, Schweizer PA, Katus HA, Thomas D. Cardiovascular pharmacology of K17.1 (TASK-4, TALK-2) two-pore-domain K channels. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 30008082 DOI: 10.1007/S00210-018-1535-Z |
0.417 |
|
| 2018 |
Chai S, Wan X, Ramirez-Navarro A, Tesar PJ, Kaufman ES, Ficker E, George AL, Deschênes I. Physiological genomics identifies genetic modifiers of long QT syndrome type 2 severity. The Journal of Clinical Investigation. PMID 29431731 DOI: 10.1172/Jci94996 |
0.389 |
|
| 2018 |
Veeraraghavan R, Hoeker GS, Alvarez-Laviada A, Hoagland D, Wan X, King DR, Sanchez-Alonso J, Chen C, Jourdan J, Isom LL, Deschenes I, Smyth JW, Gorelik J, Poelzing S, Gourdie RG. Author response: The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation Elife. DOI: 10.7554/Elife.37610.025 |
0.439 |
|
| 2018 |
Chatterjee S, Vyas R, Chalamalasetti S, Sahu ID, Clatot J, Lorigan GA, Deschenes I, Chakrapani S. Structural Dynamics of Slow-Inactivation in a Voltage-Gated Sodium Channel Biophysical Journal. 114: 38a-39a. DOI: 10.1016/J.Bpj.2017.11.262 |
0.455 |
|
| 2017 |
Clatot J, Hoshi M, Wan X, Liu H, Jain A, Shinlapawittayatorn K, Marionneau C, Ficker E, Ha T, Deschênes I. Voltage-gated sodium channels assemble and gate as dimers. Nature Communications. 8: 2077. PMID 29233994 DOI: 10.1038/S41467-017-02262-0 |
0.507 |
|
| 2017 |
Sun Y, Timofeyev V, Dennis A, Bektik E, Wan X, Laurita KR, Deschênes I, Li RA, Fu JD. A Singular Role of IK1 Promoting the Development of Cardiac Automaticity during Cardiomyocyte Differentiation by IK1 -Induced Activation of Pacemaker Current. Stem Cell Reviews. PMID 28623610 DOI: 10.1007/S12015-017-9745-1 |
0.348 |
|
| 2017 |
Nassal DM, Wan X, Liu H, Laurita KR, Deschênes I. KChIP2 regulates the cardiac Ca2+ transient and myocyte contractility by targeting ryanodine receptor activity. Plos One. 12: e0175221. PMID 28384221 DOI: 10.1371/Journal.Pone.0175221 |
0.4 |
|
| 2017 |
Chai S, Wan X, Nassal DM, Liu H, Moravec CS, Ramirez-Navarro A, Deschenes I. Contribution of two pore potassium channels to cardiac ventricular action potential revealed using human iPSC-derived cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00107.2017. PMID 28341634 DOI: 10.1152/Ajpheart.00107.2017 |
0.504 |
|
| 2017 |
Nassal MM, Wan X, Dale Z, Deschenes I, Wilson LD, Piktel JS. Mild hypothermia preserves myocardial conduction during ischemia by maintaining gap junction intracellular communication and sodium channel function. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00298.2016. PMID 28283549 DOI: 10.1152/Ajpheart.00298.2016 |
0.399 |
|
| 2017 |
Nassal DM, Wan X, Liu H, Maleski D, Ramirez-Navarro A, Moravec CS, Ficker E, Laurita KR, Deschênes I. KChIP2 is a core transcriptional regulator of cardiac excitability. Elife. 6. PMID 28263709 DOI: 10.7554/Elife.17304 |
0.374 |
|
| 2017 |
Nassal DM, Wan X, Liu H, Maleski D, Ramirez-Navarro A, Moravec CS, Ficker E, Laurita KR, Deschênes I. Author response: KChIP2 is a core transcriptional regulator of cardiac excitability Elife. DOI: 10.7554/Elife.17304.018 |
0.304 |
|
| 2017 |
Veeraraghavan R, Hoeker GS, Alvarez Laviada A, Wan X, Deschenes I, Smyth J, Gorelik J, Poelzing S, Gourdie RG. STORM and TEM Identify the Cardiac Ephapse: An Intercalated Disk Nanodomain with Previously Unanticipated Functions in Cardiac Conduction Microscopy and Microanalysis. 23: 1110-1111. DOI: 10.1017/S1431927617006213 |
0.37 |
|
| 2017 |
Clatot J, Girardeau A, Marionneau C, Deschenes I. Voltage-Gated Sodium Channel Mutations can Exert Dominant-Negative Suppression by Coupled Gating Biophysical Journal. 112: 104a. DOI: 10.1016/J.Bpj.2016.11.594 |
0.571 |
|
| 2017 |
Bettinger R, Panjshiri R, Nassal DM, Deschenes I, Jiang M, Tseng G. KChIP2 Serves Multiple Functions in Cardiac Myocytes in Splice Isoform-Dependent Manner Biophysical Journal. 112: 36a-37a. DOI: 10.1016/J.Bpj.2016.11.230 |
0.469 |
|
| 2016 |
Chiamvimonvat N, Chen-Izu Y, Clancy CE, Deschenes I, Dobrev D, Heijman J, Izu L, Qu Z, Ripplinger CM, Vandenberg JI, Weiss JN, Koren G, Banyasz T, Grandi E, Sanguinetti MC, et al. Potassium currents in the heart: Functional roles in repolarization, arrhythmia and therapeutics. The Journal of Physiology. PMID 27808412 DOI: 10.1113/Jp272883 |
0.646 |
|
| 2016 |
Sattayaprasert P, Nassal DM, Wan X, Deschenes I, Laurita KR. Mesenchymal Stem Cells Suppress Cardiac Alternans by Activation of PI3K Mediated Nitroso-Redox Pathway. Journal of Molecular and Cellular Cardiology. PMID 27238412 DOI: 10.1016/J.Yjmcc.2016.05.014 |
0.327 |
|
| 2016 |
Nassal DM, Wan X, Liu H, Deschênes I. Myocardial KChIP2 Expression in Guinea Pig Resolves an Expanded Electrophysiologic Role. Plos One. 11: e0146561. PMID 26764482 DOI: 10.1371/Journal.Pone.0146561 |
0.525 |
|
| 2015 |
Hoshi M, Liu H, Kaufman ES, Deschênes I. Polygenic Case of Long QT Syndrome Confirmed through Functional Characterization Informs the Interpretation of Genetic Screening Results. Heartrhythm Case Reports. 1: 201-205. PMID 26213684 DOI: 10.1016/J.Hrcr.2015.02.011 |
0.408 |
|
| 2015 |
Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, et al. Na+ channel function, regulation, structure, trafficking and sequestration. The Journal of Physiology. 593: 1347-60. PMID 25772290 DOI: 10.1113/Jphysiol.2014.281428 |
0.657 |
|
| 2015 |
Plummer BN, Liu H, Wan X, Deschênes I, Laurita KR. Targeted antioxidant treatment decreases cardiac alternans associated with chronic myocardial infarction. Circulation. Arrhythmia and Electrophysiology. 8: 165-73. PMID 25491741 DOI: 10.1161/Circep.114.001789 |
0.307 |
|
| 2015 |
Clatot J, Liu H, Ficker E, Deschênes I. Interaction of the Cardiac Sodium Channel Alpha-Subunits Leads to Coupled Gating Properties Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.3132 |
0.535 |
|
| 2014 |
Ziyadeh-Isleem A, Clatot J, Duchatelet S, Gandjbakhch E, Denjoy I, Hidden-Lucet F, Hatem S, Deschênes I, Coulombe A, Neyroud N, Guicheney P. A truncating SCN5A mutation combined with genetic variability causes sick sinus syndrome and early atrial fibrillation. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 11: 1015-23. PMID 24582607 DOI: 10.1016/J.Hrthm.2014.02.021 |
0.506 |
|
| 2014 |
Neyroud N, Ziyadeh-Isleem A, Clatot J, Deschenes I, Coulombe A, Guicheney P. P371Role of the N- and distal C-terminal domains in Nav1.5 alpha-subunit interaction Cardiovascular Research. 103. DOI: 10.1093/Cvr/Cvu091.54 |
0.529 |
|
| 2014 |
Nassal DM, Liu H, Wan X, Ficker E, Deschenes I. Novel Role for Kchip2 as a Transcriptional Regulator of Cardiac Genes Biophysical Journal. 106: 750a. DOI: 10.1016/J.Bpj.2013.11.4130 |
0.315 |
|
| 2014 |
Clatot J, Liu H, Ficker E, Deschenes I. Cardiac Sodium Channel Display Coupled Gating Biophysical Journal. 106: 326-326. DOI: 10.1016/J.Bpj.2013.11.1878 |
0.562 |
|
| 2013 |
Jeyaraj D, Wan X, Ficker E, Stelzer JE, Deschenes I, Liu H, Wilson LD, Decker KF, Said TH, Jain MK, Rudy Y, Rosenbaum DS. Ionic bases for electrical remodeling of the canine cardiac ventricle. American Journal of Physiology. Heart and Circulatory Physiology. 305: H410-9. PMID 23709598 DOI: 10.1152/Ajpheart.00213.2013 |
0.365 |
|
| 2013 |
Jehle J, Ficker E, Wan X, Deschenes I, Kisselbach J, Wiedmann F, Staudacher I, Schmidt C, Schweizer PA, Becker R, Katus HA, Thomas D. Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells. British Journal of Pharmacology. 168: 1215-29. PMID 23061993 DOI: 10.1111/Bph.12002 |
0.479 |
|
| 2013 |
Clatot J, Ziyadeh-Isleem A, Duchatelet S, Gandjbakhch E, Denjoy I, Hidden-Lucet F, Hatem S, Coulombe A, Neyroud N, Deschênes I, Guicheney P. Different Atrial and Ventricular Resting Membrane Potentials May Explain the Phenotypical Variability of a Truncating SCN5A Mutation Heart Rhythm. 10: 1746. DOI: 10.1016/J.Hrthm.2013.09.028 |
0.512 |
|
| 2013 |
Hoshi M, Shinlapawittayatorn K, Chai S, Du XX, Liu H, Wan X, Ficker E, Deschenes I. Erratum: Wild-type sodium channels and 'Atypical' Brugada syndrome mutants interact through C-terminal region (Biophysical Journal (2013) 104:2 (133a)) Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2013.03.003 |
0.4 |
|
| 2013 |
Jehle J, Wan X, Deschenes I, Thomas D, Ficker E. Analysis of Zolpidem-Induced Long Qt Syndrome in Recombinant hERG Channels and Stem Cell Derived Human Cardiomyocytes Biophysical Journal. 104: 298a. DOI: 10.1016/J.Bpj.2012.11.1661 |
0.374 |
|
| 2012 |
Cutler MJ, Plummer BN, Wan X, Sun QA, Hess D, Liu H, Deschenes I, Rosenbaum DS, Stamler JS, Laurita KR. Aberrant S-nitrosylation mediates calcium-triggered ventricular arrhythmia in the intact heart. Proceedings of the National Academy of Sciences of the United States of America. 109: 18186-91. PMID 23071315 DOI: 10.1073/Pnas.1210565109 |
0.312 |
|
| 2012 |
Cutler MJ, Wan X, Plummer BN, Liu H, Deschenes I, Laurita KR, Hajjar RJ, Rosenbaum DS. Targeted sarcoplasmic reticulum Ca2+ ATPase 2a gene delivery to restore electrical stability in the failing heart. Circulation. 126: 2095-104. PMID 23019291 DOI: 10.1161/Circulationaha.111.071480 |
0.349 |
|
| 2012 |
Clatot J, Ziyadeh-Isleem A, Maugenre S, Denjoy I, Liu H, Dilanian G, Hatem SN, Deschênes I, Coulombe A, Guicheney P, Neyroud N. Dominant-negative effect of SCN5A N-terminal mutations through the interaction of Na(v)1.5 α-subunits. Cardiovascular Research. 96: 53-63. PMID 22739120 DOI: 10.1093/Cvr/Cvs211 |
0.47 |
|
| 2012 |
Dennis AT, Wang L, Wan H, Nassal D, Deschenes I, Ficker E. Molecular determinants of pentamidine-induced hERG trafficking inhibition. Molecular Pharmacology. 81: 198-209. PMID 22046004 DOI: 10.1124/Mol.111.075135 |
0.504 |
|
| 2011 |
Shinlapawittayatorn K, Dudash LA, Du XX, Heller L, Poelzing S, Ficker E, Deschênes I. A novel strategy using cardiac sodium channel polymorphic fragments to rescue trafficking-deficient SCN5A mutations. Circulation. Cardiovascular Genetics. 4: 500-9. PMID 21840964 DOI: 10.1161/Circgenetics.111.960633 |
0.706 |
|
| 2011 |
Dennis AT, Nassal D, Deschenes I, Thomas D, Ficker E. Antidepressant-induced ubiquitination and degradation of the cardiac potassium channel hERG. The Journal of Biological Chemistry. 286: 34413-25. PMID 21832094 DOI: 10.1074/Jbc.M111.254367 |
0.492 |
|
| 2011 |
Shinlapawittayatorn K, Du XX, Liu H, Ficker E, Kaufman ES, Deschênes I. A common SCN5A polymorphism modulates the biophysical defects of SCN5A mutations. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 8: 455-62. PMID 21109022 DOI: 10.1016/J.Hrthm.2010.11.034 |
0.665 |
|
| 2011 |
Shinlapawittayatorn K, Nassal DM, Liu H, Ficker E, Deschenes I. Dominant-Negative Suppression of Sodium Channel Activity by a Brugada Syndrome Mutation Observed in Cardiomyocytes Biophysical Journal. 100: 424a. DOI: 10.1016/J.Bpj.2010.12.2508 |
0.562 |
|
| 2010 |
Hsu K, Han J, Shinlapawittayatorn K, Deschenes I, Marbán E. Membrane potential depolarization as a triggering mechanism for Vpu-mediated HIV-1 release. Biophysical Journal. 99: 1718-25. PMID 20858415 DOI: 10.1016/J.Bpj.2010.07.027 |
0.307 |
|
| 2010 |
Du X, Enweana P, Shinlapawittayatorn K, Deschênes I. A Novel Mechanism of Action for Sodium Channel Brugada Syndrome Mutations Heart Rhythm. 7: 1716. DOI: 10.1016/J.Hrthm.2010.09.041 |
0.501 |
|
| 2010 |
Shinlapawittayatorn K, Du X, Liu H, Ficker E, Deschenes I. Do Sodium Channel α - α Interactions Contribute to Loss-of-Function Observed in Brugada Syndrome? Biophysical Journal. 98: 311a. DOI: 10.1016/J.Bpj.2009.12.1691 |
0.7 |
|
| 2009 |
Shinlapawittayatorn K, Du X, Liu H, Kaufman ES, Deschenes I. A Common SCN5A Polymorphism Restores the Biophysical Defects of LQT3 Mutations Biophysical Journal. 96: 249a. DOI: 10.1016/J.Bpj.2008.12.1227 |
0.65 |
|
| 2008 |
Christé G, Thériault O, Chahine M, Millat G, Rodriguez-Lafrasse C, Rousson R, Deschênes I, Ficker E, Chevalier P. A new C-terminal hERG mutation A915fs+47X associated with symptomatic LQT2 and auditory-trigger syncope. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 5: 1577-86. PMID 18984536 DOI: 10.1016/J.Hrthm.2008.08.031 |
0.529 |
|
| 2008 |
Deschênes I, Armoundas AA, Jones SP, Tomaselli GF. Post-transcriptional gene silencing of KChIP2 and Navbeta1 in neonatal rat cardiac myocytes reveals a functional association between Na and Ito currents. Journal of Molecular and Cellular Cardiology. 45: 336-46. PMID 18565539 DOI: 10.1016/J.Yjmcc.2008.05.001 |
0.443 |
|
| 2008 |
Biswas S, Deschênes I, Disilvestre D, Tian Y, Halperin VL, Tomaselli GF. Calmodulin regulation of Nav1.4 current: role of binding to the carboxyl terminus. The Journal of General Physiology. 131: 197-209. PMID 18270170 DOI: 10.1085/jgp.200709863 |
0.349 |
|
| 2008 |
Kjølbye AL, Dikshteyn M, Eloff BC, Deschênes I, Rosenbaum DS. Maintenance of intercellular coupling by the antiarrhythmic peptide rotigaptide suppresses arrhythmogenic discordant alternans. American Journal of Physiology. Heart and Circulatory Physiology. 294: H41-9. PMID 17982010 DOI: 10.1152/Ajpheart.01089.2006 |
0.316 |
|
| 2007 |
Jeyaraj D, Wilson LD, Zhong J, Flask C, Saffitz JE, Deschênes I, Yu X, Rosenbaum DS. Mechanoelectrical feedback as novel mechanism of cardiac electrical remodeling. Circulation. 115: 3145-55. PMID 17562957 DOI: 10.1161/Circulationaha.107.688317 |
0.412 |
|
| 2007 |
Deschênes I, Laurita KR. How can a single mutation cause such arrhythmic havoc? Heart Rhythm : the Official Journal of the Heart Rhythm Society. 4: 198-9. PMID 17275756 DOI: 10.1016/J.Hrthm.2006.11.010 |
0.447 |
|
| 2006 |
Poelzing S, Forleo C, Samodell M, Dudash L, Sorrentino S, Anaclerio M, Troccoli R, Iacoviello M, Romito R, Guida P, Chahine M, Pitzalis M, Deschênes I. SCN5A polymorphism restores trafficking of a Brugada syndrome mutation on a separate gene. Circulation. 114: 368-76. PMID 16864729 DOI: 10.1161/Circulationaha.105.601294 |
0.633 |
|
| 2004 |
Akar FG, Wu RC, Deschenes I, Armoundas AA, Piacentino V, Houser SR, Tomaselli GF. Phenotypic differences in transient outward K+ current of human and canine ventricular myocytes: insights into molecular composition of ventricular Ito. American Journal of Physiology. Heart and Circulatory Physiology. 286: H602-9. PMID 14527940 DOI: 10.1152/Ajpheart.00673.2003 |
0.43 |
|
| 2002 |
Deschênes I, Tomaselli GF. Modulation of Kv4.3 current by accessory subunits. Febs Letters. 528: 183-8. PMID 12297301 DOI: 10.1016/S0014-5793(02)03296-9 |
0.447 |
|
| 2002 |
Deschênes I, DiSilvestre D, Juang GJ, Wu RC, An WF, Tomaselli GF. Regulation of Kv4.3 current by KChIP2 splice variants: a component of native cardiac I(to)? Circulation. 106: 423-9. PMID 12135940 DOI: 10.1161/01.Cir.0000025417.65658.B6 |
0.47 |
|
| 2001 |
Deschênes I, Trottier E, Chahine M. Implication of the C-terminal region of the alpha-subunit of voltage-gated sodium channels in fast inactivation. The Journal of Membrane Biology. 183: 103-14. PMID 11562792 DOI: 10.1007/S00232-001-0058-5 |
0.643 |
|
| 2000 |
Deschênes I, Baroudi G, Berthet M, Barde I, Chalvidan T, Denjoy I, Guicheney P, Chahine M. Electrophysiological characterization of SCN5A mutations causing long QT (E1784K) and Brugada (R1512W and R1432G) syndromes. Cardiovascular Research. 46: 55-65. PMID 10727653 DOI: 10.1016/S0008-6363(00)00006-7 |
0.574 |
|
| 1999 |
Deschênes I, Trottier E, Chahine M. Cysteine scanning analysis of the IFM cluster in the inactivation gate of a human heart sodium channel. Cardiovascular Research. 42: 521-9. PMID 10533587 DOI: 10.1016/S0008-6363(99)00064-4 |
0.64 |
|
| 1998 |
Deschênes I, Chen L, Kallen RG, Chahine M. Electrophysiological study of chimeric sodium channels from heart and skeletal muscle. The Journal of Membrane Biology. 164: 25-34. PMID 9636241 DOI: 10.1007/S002329900390 |
0.627 |
|
| 1997 |
Chahine M, Deschênes I, Trottier E, Chen LQ, Kallen RG. Restoration of fast inactivation in an inactivation-defective human heart sodium channel by the cysteine modifying reagent benzyl-MTS: analysis of IFM-ICM mutation. Biochemical and Biophysical Research Communications. 233: 606-10. PMID 9168898 DOI: 10.1006/Bbrc.1997.6510 |
0.663 |
|
| 1997 |
Deschênes I, Chahine M, Tremblay J, Paulin D, Puymirat J. Increase in the proliferative capacity of human myoblasts by using the T antigen under the vimentin promoter control. Muscle & Nerve. 20: 437-45. PMID 9121501 DOI: 10.1002/(Sici)1097-4598(199704)20:4<437::Aid-Mus6>3.0.Co;2-B |
0.484 |
|
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