Year |
Citation |
Score |
2018 |
Lin EYS, Silvian LF, Marcotte DJ, Banos CC, Jow F, Chan TR, Arduini RM, Qian F, Baker DP, Bergeron C, Hession CA, Huganir RL, Borenstein CF, Enyedy I, Zou J, ... ... Scannevin RH, et al. Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction. Scientific Reports. 8: 13438. PMID 30194389 DOI: 10.1038/S41598-018-31680-3 |
0.563 |
|
2017 |
Brennan MS, Matos MF, Richter KE, Li B, Scannevin RH. The NRF2 transcriptional target, OSGIN1, contributes to monomethyl fumarate-mediated cytoprotection in human astrocytes. Scientific Reports. 7: 42054. PMID 28181536 DOI: 10.1038/Srep42054 |
0.328 |
|
2016 |
Peng H, Li H, Sheehy A, Cullen P, Allaire N, Scannevin RH. Dimethyl fumarate alters microglia phenotype and protects neurons against proinflammatory toxic microenvironments. Journal of Neuroimmunology. 299: 35-44. PMID 27725119 DOI: 10.1016/j.jneuroim.2016.08.006 |
0.319 |
|
2016 |
Sevigny J, Chiao P, Bussière T, Weinreb PH, Williams L, Maier M, Dunstan R, Salloway S, Chen T, Ling Y, O'Gorman J, Qian F, Arastu M, Li M, Chollate S, ... ... Scannevin RH, et al. The antibody aducanumab reduces Aβ plaques in Alzheimer's disease. Nature. 537: 50-6. PMID 27582220 DOI: 10.1038/nature19323 |
0.31 |
|
2015 |
Scannevin RH, Chollate S, Brennan MS, Snodgrass-Belt PA, Peng H, Xu L, Jung MY, Bussiere T, Arastu MF, Talreja T, Xin Z, Dunstan RW, Fahrer D, Rohde E, Dunah AW, et al. BIIB042, a novel γ-secretase modulator, reduces amyloidogenic Aβ isoforms in primates and rodents and plaque pathology in a mouse model of Alzheimer's disease. Neuropharmacology. PMID 26690893 DOI: 10.1016/j.neuropharm.2015.12.006 |
0.331 |
|
2015 |
Bell KF, Al-Mubarak B, Martel MA, McKay S, Wheelan N, Hasel P, Márkus NM, Baxter P, Deighton RF, Serio A, Bilican B, Chowdhry S, Meakin PJ, Ashford ML, Wyllie DJ, ... Scannevin RH, et al. Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2. Nature Communications. 6: 7066. PMID 25967870 DOI: 10.1038/Ncomms8066 |
0.306 |
|
2015 |
Parodi B, Rossi S, Morando S, Cordano C, Bragoni A, Motta C, Usai C, Wipke BT, Scannevin RH, Mancardi GL, Centonze D, Kerlero de Rosbo N, Uccelli A. Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS. Acta Neuropathologica. 130: 279-95. PMID 25920452 DOI: 10.1007/S00401-015-1422-3 |
0.398 |
|
2015 |
Brennan MS, Matos MF, Li B, Hronowski X, Gao B, Juhasz P, Rhodes KJ, Scannevin RH. Dimethyl fumarate and monoethyl fumarate exhibit differential effects on KEAP1, NRF2 activation, and glutathione depletion in vitro. Plos One. 10: e0120254. PMID 25793262 DOI: 10.1371/journal.pone.0120254 |
0.304 |
|
2014 |
Alfonso S, Kessels HW, Banos CC, Chan TR, Lin ET, Kumaravel G, Scannevin RH, Rhodes KJ, Huganir R, Guckian KM, Dunah AW, Malinow R. Synapto-depressive effects of amyloid beta require PICK1. The European Journal of Neuroscience. 39: 1225-33. PMID 24713001 DOI: 10.1111/Ejn.12499 |
0.569 |
|
2012 |
Scannevin RH, Chollate S, Jung MY, Shackett M, Patel H, Bista P, Zeng W, Ryan S, Yamamoto M, Lukashev M, Rhodes KJ. Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway. The Journal of Pharmacology and Experimental Therapeutics. 341: 274-84. PMID 22267202 DOI: 10.1124/Jpet.111.190132 |
0.306 |
|
2011 |
Wu J, Petralia RS, Kurushima H, Patel H, Jung MY, Volk L, Chowdhury S, Shepherd JD, Dehoff M, Li Y, Kuhl D, Huganir RL, Price DL, Scannevin R, Troncoso JC, et al. Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation. Cell. 147: 615-28. PMID 22036569 DOI: 10.1016/J.Cell.2011.09.036 |
0.672 |
|
2001 |
Manganas LN, Wang Q, Scannevin RH, Antonucci DE, Rhodes KJ, Trimmer JS. Identification of a trafficking determinant localized to the Kv1 potassium channel pore. Proceedings of the National Academy of Sciences of the United States of America. 98: 14055-9. PMID 11698661 DOI: 10.1073/Pnas.241403898 |
0.682 |
|
2001 |
Liao D, Scannevin RH, Huganir R. Activation of silent synapses by rapid activity-dependent synaptic recruitment of AMPA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6008-17. PMID 11487624 |
0.492 |
|
2001 |
Liao D, Scannevin RH, Huganir R. Activation of Silent Synapses by Rapid Activity-Dependent Synaptic Recruitment of AMPA Receptors The Journal of Neuroscience. 21: 6008-6017. DOI: 10.1523/Jneurosci.21-16-06008.2001 |
0.615 |
|
2000 |
Scannevin RH, Huganir RL. Postsynaptic organization and regulation of excitatory synapses. Nature Reviews. Neuroscience. 1: 133-41. PMID 11252776 DOI: 10.1038/35039075 |
0.532 |
|
2000 |
Chung HJ, Xia J, Scannevin RH, Zhang X, Huganir RL. Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7258-67. PMID 11007883 DOI: 10.1523/Jneurosci.20-19-07258.2000 |
0.7 |
|
2000 |
Lim ST, Antonucci DE, Scannevin RH, Trimmer JS. A novel targeting signal for proximal clustering of the Kv2.1 K+ channel in hippocampal neurons. Neuron. 25: 385-97. PMID 10719893 DOI: 10.1016/S0896-6273(00)80902-2 |
0.564 |
|
1997 |
Murakoshi H, Shi G, Scannevin RH, Trimmer JS. Phosphorylation of the Kv2.1 K+ channel alters voltage-dependent activation. Molecular Pharmacology. 52: 821-8. PMID 9351973 DOI: 10.1124/Mol.52.5.821 |
0.581 |
|
1997 |
Scannevin RH, Trimmer JS. Cytoplasmic domains of voltage-sensitive K+ channels involved in mediating protein-protein interactions. Biochemical and Biophysical Research Communications. 232: 585-9. PMID 9126317 DOI: 10.1006/bbrc.1997.6333 |
0.554 |
|
1996 |
Scannevin RH, Murakoshi H, Rhodes KJ, Trimmer JS. Identification of a cytoplasmic domain important in the polarized expression and clustering of the Kv2.1 K+ channel. The Journal of Cell Biology. 135: 1619-32. PMID 8978827 DOI: 10.1083/jcb.135.6.1619 |
0.549 |
|
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