| Year |
Citation |
Score |
| 2024 |
Tsang YP, Hao T, Mao Q, Kelly EJ, Unadkat JD. Dysregulation of the mRNA Expression of Human Renal Drug Transporters by Proinflammatory Cytokines in Primary Human Proximal Tubular Epithelial Cells. Pharmaceutics. 16. PMID 38399338 DOI: 10.3390/pharmaceutics16020285 |
0.316 |
|
| 2023 |
Yin M, Balhara A, Marie S, Tournier N, Gáborik Z, Unadkat JD. Successful Prediction of Human Hepatic Concentrations of Transported Drugs Using the Proteomics-Informed Relative Expression Factor Approach. Clinical Pharmacology and Therapeutics. PMID 38037845 DOI: 10.1002/cpt.3123 |
0.353 |
|
| 2022 |
Storelli F, Yin M, Kumar AR, Ladumor MK, Evers R, Chothe PP, Enogieru OJ, Liang X, Lai Y, Unadkat JD. The next frontier in ADME science: Predicting transporter-based drug disposition, tissue concentrations and drug-drug interactions in humans. Pharmacology & Therapeutics. 108271. PMID 36002079 DOI: 10.1016/j.pharmthera.2022.108271 |
0.341 |
|
| 2022 |
Yin M, Storelli F, Unadkat JD. Is the Protein-Mediated Uptake of Drugs by Organic Anion Transporting Polypeptides a Real Phenomenon or an Artifact? Drug Metabolism and Disposition: the Biological Fate of Chemicals. 50: 1132-1141. PMID 35351775 DOI: 10.1124/dmd.122.000849 |
0.305 |
|
| 2022 |
Storelli F, Li CY, Sachar M, Kumar V, Heyward S, Sáfár Z, Kis E, Unadkat JD. Prediction of Hepatobiliary Clearances and Hepatic Concentrations of Transported Drugs in Humans Using Rosuvastatin as a Model Drug. Clinical Pharmacology and Therapeutics. PMID 35152400 DOI: 10.1002/cpt.2556 |
0.315 |
|
| 2021 |
Chen X, Unadkat JD, Mao Q. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 34326138 DOI: 10.1124/dmd.121.000505 |
0.333 |
|
| 2021 |
Storelli F, Anoshchenko O, Unadkat JD. Successful prediction of human brain K of P-gp substrates using the proteomics-informed relative expression factor approach. Clinical Pharmacology and Therapeutics. PMID 33675056 DOI: 10.1002/cpt.2227 |
0.316 |
|
| 2020 |
Nguyen JT, Tian DD, Tanna RS, Hadi DL, Bansal S, Calamia JC, Arian CM, Shireman LM, Molnár B, Horváth M, Kellogg JJ, Layton ME, White JR, Cech NB, Boyce RD, ... Unadkat JD, et al. Assessing Transporter-Mediated Natural Product-Drug Interactions via In vitro-In vivo Extrapolation: Clinical Evaluation with a Probe Cocktail. Clinical Pharmacology and Therapeutics. PMID 33174626 DOI: 10.1002/cpt.2107 |
0.35 |
|
| 2020 |
Kumar V, Yin M, Ishida K, Salphati L, Hop CECA, Rowbottom C, Xiao G, Lai Y, Mathias A, Chu X, Humphreys WG, Liao M, Nerada Z, Szilvásy N, Heyward S, ... Unadkat JD, et al. Prediction of Transporter-Mediated Rosuvastatin Hepatic Uptake Clearance and Drug Interaction in Humans Using Proteomics-Informed REF Approach. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 33051248 DOI: 10.1124/dmd.120.000204 |
0.702 |
|
| 2020 |
Storelli F, Billington S, Kumar AR, Unadkat JD. Abundance of P-glycoprotein and other drug transporters at the human blood-brain barrier in Alzheimer's Disease: a quantitative targeted proteomic study. Clinical Pharmacology and Therapeutics. PMID 32885413 DOI: 10.1002/Cpt.2035 |
0.424 |
|
| 2020 |
Sachar M, Kumar V, Gormsen LC, Munk OL, Unadkat JD. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32843330 DOI: 10.1124/Dmd.120.000156 |
0.434 |
|
| 2020 |
Kumar V, Li CY, Ishida K, Kis E, Gáborik Z, Unadkat JD. Pitfalls in Predicting Hepatobiliary Drug Transport Using Human Sandwich-Cultured Hepatocytes. The Aaps Journal. 22: 110. PMID 32808154 DOI: 10.1208/S12248-020-00496-3 |
0.342 |
|
| 2020 |
Anoshchenko O, Prasad B, Neradugomma NK, Wang J, Mao Q, Unadkat JD. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32591415 DOI: 10.1124/Dmd.120.000067 |
0.394 |
|
| 2020 |
Bansal S, Maharao N, Paine MF, Unadkat JD. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32587099 DOI: 10.1124/Dmd.120.000073 |
0.327 |
|
| 2020 |
Unadkat JD. SC1.1 - The next frontier in adme research: Predicting and verifying tissue drug concentrations using a proteomics and pet imaging approach Drug Metabolism and Pharmacokinetics. 35. DOI: 10.1016/J.Dmpk.2020.04.268 |
0.303 |
|
| 2020 |
Li CY, Hosey-Cojocari C, Basit A, Unadkat JD, Leeder JS, Prasad B. A11 - Optimized renal transporter quantification by using Aquaporin 1 and Aquaporin 2 as anatomical markers: Application in characterizing the ontogeny of renal transporters and its correlation with hepatic transporters in paired sample Drug Metabolism and Pharmacokinetics. 35. DOI: 10.1016/J.Dmpk.2020.04.265 |
0.337 |
|
| 2020 |
Kumar V, Ishida K, Salphati L, Hop CECA, Rowbottom C, Xiao G, Lai Y, Mathias A, Chu X, Humphreys WG, Liao M, Tóth B, Szilvásy N, Heyward S, Unadkat JD. P129 - In-vivo transporter-mediated hepatic clearance of rosuvastatin in humans could be better predicted using transporter-expressing cells than hepatocytes Drug Metabolism and Pharmacokinetics. 35. DOI: 10.1016/J.Dmpk.2020.04.130 |
0.718 |
|
| 2019 |
Li CY, Hosey-Cojocari C, Basit A, Unadkat JD, Leeder JS, Prasad B. Optimized Renal Transporter Quantification by Using Aquaporin 1 and Aquaporin 2 as Anatomical Markers: Application in Characterizing the Ontogeny of Renal Transporters and Its Correlation with Hepatic Transporters in Paired Human Samples. The Aaps Journal. 21: 88. PMID 31297641 DOI: 10.1208/S12248-019-0359-1 |
0.362 |
|
| 2019 |
Zhang D, Hop CE, Patilea-Vrana G, Gampa G, Seneviratne HK, Unadkat JD, Kenny JR, Nagapudi K, Di L, Zhou L, Zak M, Wright MR, Bumpus NN, Zang R, Liu X, et al. Drug Concentration Asymmetry in Tissues and Plasma for Small Molecule-Related Therapeutic Modalities. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31266753 DOI: 10.1124/Dmd.119.086744 |
0.369 |
|
| 2019 |
Billington S, Shoner S, Lee S, Clark-Snustad K, Pennington M, Lewis D, Muzi M, Rene S, Lee J, Nguyen TB, Kumar V, Ishida K, Chen L, Chu X, Lai Y, ... ... Unadkat JD, et al. PET Imaging of [ C]Rosuvastatin Hepatic Concentrations and Hepatobiliary Transport in Humans in the Absence and Presence of Cyclosporine A. Clinical Pharmacology and Therapeutics. PMID 31102467 DOI: 10.1002/Cpt.1506 |
0.378 |
|
| 2019 |
Cox EJ, Maharao N, Patilea-Vrana G, Unadkat JD, Rettie AE, McCune JS, Paine MF. A marijuana-drug interaction primer: Precipitants, pharmacology, and pharmacokinetics. Pharmacology & Therapeutics. PMID 31071346 DOI: 10.1016/J.Pharmthera.2019.05.001 |
0.304 |
|
| 2019 |
Patilea-Vrana GI, Unadkat JD. Quantifying hepatic enzyme kinetics of (-)-Δ-tetrahydrocannabinol (THC) and its psychoactive metabolite, 11-OH-THC, through in vitro modeling. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31048453 DOI: 10.1124/Dmd.119.086470 |
0.34 |
|
| 2019 |
Sachar M, Kelly EJ, Unadkat JD. Mechanisms of CYP3A Induction During Pregnancy: Studies in HepaRG Cells. The Aaps Journal. 21: 45. PMID 30919109 DOI: 10.1208/S12248-019-0316-Z |
0.367 |
|
| 2019 |
Billington S, Salphati L, Hop CECA, Chu X, Evers R, Burdette D, Rowbottom C, Lai Y, Xiao G, Humphreys WG, Nguyen TB, Prasad B, Unadkat JD. Inter-Individual and Regional Variability in Drug Transporter Abundance at the Human Blood-Brain Barrier Measured by Quantitative Targeted Proteomics. Clinical Pharmacology and Therapeutics. PMID 30673124 DOI: 10.1002/Cpt.1373 |
0.45 |
|
| 2019 |
Kumar V, Salphati L, Hop CECA, Xiao G, Lai Y, Mathias A, Chu X, Humphreys WG, Liao M, Heyward S, Unadkat JD. A Comparison of Total and Plasma Membrane Abundance of Transporters in Suspended, Plated, Sandwich-Cultured Human Hepatocytes vs. Human Liver Tissue Using Quantitative Targeted Proteomics and Cell-Surface Biotinylation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 30622164 DOI: 10.1124/Dmd.118.084988 |
0.716 |
|
| 2019 |
Kumar V, Salphati L, Hop CE, Rowbottom C, Xiao G, Lai Y, Mathias A, Chu X, Humphreys WG, Liao M, Chen L, Tóth B, Juhasz V, Heyward S, Unadkat J. Can transporter-expressing cells predict rosuvastatin uptake clearance in suspended or plated human hepatocytes? Drug Metabolism and Pharmacokinetics. 34: S22-S23. DOI: 10.1016/J.Dmpk.2018.09.094 |
0.691 |
|
| 2019 |
Kumar V, Salphati L, Hop CE, Rowbottom C, Xiao G, Lai Y, Mathias A, Chu X, Humphreys W, Liao M, Chen L, Heyward S, Unadkat J. Does plasma membrane and total transporter abundance differ between suspended, plated, sandwich culture hepatocytes and human liver tissue? Drug Metabolism and Pharmacokinetics. 34: S17. DOI: 10.1016/J.Dmpk.2018.09.078 |
0.672 |
|
| 2019 |
Patilea-Vrana G, Unadkat J. Novel insights into predicting hepatic DDI liabilities when transporters and enzymes are involved Drug Metabolism and Pharmacokinetics. 34: 15. DOI: 10.1016/J.Dmpk.2018.09.073 |
0.364 |
|
| 2019 |
Unadkat J. Predicting and verifying maternal-fetal exposure to drugs during pregnancy Drug Metabolism and Pharmacokinetics. 34. DOI: 10.1016/J.Dmpk.2018.09.036 |
0.303 |
|
| 2018 |
Patilea-Vrana GI, Anoshchenko O, Unadkat JD. Hepatic enzymes relevant to the disposition of (-)-Δ-tetrahydrocannabinol (THC) and its psychoactive metabolite, 11-OH-THC. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 30567877 DOI: 10.1124/Dmd.118.085548 |
0.32 |
|
| 2018 |
McFeely SJ, Wu L, Ritchie TK, Unadkat J. Organic Anion Transporting Polypeptide 2B1 - More than a Glass-Full of Drug Interactions. Pharmacology & Therapeutics. PMID 30557631 DOI: 10.1016/J.Pharmthera.2018.12.009 |
0.401 |
|
| 2018 |
Xu M, Saxena N, Vrana M, Zhang H, Kumar V, Billington S, Khojasteh C, Heyward S, Unadkat JD, Prasad B. A Targeted LC-MS/MS Proteomics-Based Strategy to Characterize In Vitro Models Used in Drug Metabolism and Transport Studies. Analytical Chemistry. PMID 30204418 DOI: 10.1021/Acs.Analchem.8B01913 |
0.357 |
|
| 2018 |
Patilea-Vrana GI, Unadkat JD. When Does the Rate-Determining Step in the Hepatic Clearance of a Drug Switch from Sinusoidal Uptake to All Hepatobiliary Clearances? Implications for Predicting Drug-Drug Interactions. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 46: 1487-1496. PMID 30115647 DOI: 10.1124/Dmd.118.081307 |
0.423 |
|
| 2018 |
Kumar V, Yin J, Billington S, Prasad B, Brown C, Wang J, Unadkat JD. The importance of incorporating OCT2 plasma membrane expression and membrane potential in IVIVE of metformin renal secretory clearance. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 30093416 DOI: 10.1124/Dmd.118.082313 |
0.377 |
|
| 2018 |
Zamek-Gliszczynski MJ, Taub ME, Chothe PP, Chu X, Giacomini KM, Kim RB, Ray AS, Stocker SL, Unadkat JD, Wittwer MB, Xia C, Yee SW, Zhang L, Zhang Y. Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance. Clinical Pharmacology and Therapeutics. PMID 30091177 DOI: 10.1002/Cpt.1112 |
0.413 |
|
| 2018 |
Guo Y, Chu X, Parrott NJ, Brouwer KLR, Hsu V, Nagar S, Matsson P, Sharma P, Snoeys J, Sugiyama Y, Tatosian D, Unadkat JD, Huang SM, Galetin A. Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro, Imaging and PBPK Modeling Approaches. Clinical Pharmacology and Therapeutics. PMID 30059145 DOI: 10.1002/Cpt.1183 |
0.372 |
|
| 2018 |
Ishida K, Ullah M, Toth B, Juhasz V, Unadkat JD. Transport Kinetics, Selective Inhibition, and Successful Prediction of In Vivo Inhibition of Rat Hepatic Oatps. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29891589 DOI: 10.1124/Dmd.118.080770 |
0.412 |
|
| 2018 |
Zou L, Stecula A, Gupta A, Prasad B, Chien HC, Yee SW, Wang L, Unadkat JD, Stahl SH, Fenner KS, Giacomini KM. Molecular Mechanisms for Species Differences in Organic Anion Transporter 1, OAT1: Implications for Renal Drug Toxicity. Molecular Pharmacology. PMID 29720497 DOI: 10.1124/Mol.117.111153 |
0.38 |
|
| 2018 |
Prasad B, Bhatt DK, Johnson K, Chapa R, Chu X, Salphati L, Xiao G, Lee C, Hop CE, Mathias A, Lai Y, Liao M, Humphreys WG, Kumer SC, Unadkat JD. Abundance of Phase I and II Drug Metabolizing Enzymes in Alcoholic and Hepatitis C Cirrhotic Livers: A Quantitative Targeted Proteomics Study. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29695616 DOI: 10.1124/Dmd.118.080523 |
0.65 |
|
| 2018 |
Anoshchenko O, Prasad B, Unadkat JD. Gestational age-dependent abundance of drug transporters and metabolizing enzymes in human placentae quantified by LC–MS/MS proteomics Drug Metabolism and Pharmacokinetics. 33: S97. DOI: 10.1016/J.Dmpk.2017.11.312 |
0.384 |
|
| 2018 |
Ishida K, Ullah M, Tóth B, Juhász V, Unadkat JD. Determination of fraction of a drug transported by rat Oatps through identification and use of selective Oatp inhibitors Drug Metabolism and Pharmacokinetics. 33: S94. DOI: 10.1016/J.Dmpk.2017.11.305 |
0.378 |
|
| 2018 |
Patilea-Vrana G, Unadkat JD. When does the rate-determining step in hepatic clearance of a drug switch from sinusoidal uptake clearance to all hepatobiliary clearances? Drug Metabolism and Pharmacokinetics. 33. DOI: 10.1016/J.Dmpk.2017.11.107 |
0.35 |
|
| 2018 |
Kumar V, Nguyen TB, Tóth B, Juhász V, Unadkat JD. Are OATP1B1, OATP2B1, OATP1B3 and NTCP transporters exclusively expressed in the plasma membrane of transporter-expressing cells? Drug Metabolism and Pharmacokinetics. 33: S20-S21. DOI: 10.1016/J.Dmpk.2017.11.086 |
0.372 |
|
| 2018 |
Billington SF, Ray AS, Salphati L, Xiao G, Chu X, Humphreys WG, Liao M, Lee C, Mathias A, Hop CECA, Rowbottom C, Evers R, Lai Y, Kelly EJ, Prasad B, ... Unadkat JD, et al. Transporter expression in non-cancerous and cancerous liver tissue from subjects with hepatocellular carcinoma and chronic hepatitis C infection quantified by LC-MS/MS proteomics Drug Metabolism and Pharmacokinetics. 33. DOI: 10.1016/J.Dmpk.2017.11.081 |
0.642 |
|
| 2017 |
Billington S, Ray AS, Salphati L, Xiao G, Chu X, Humphreys WG, Liao M, Lee CA, Mathias AA, Hop CECA, Rowbottom C, Evers R, Lai Y, Kelly EJ, Prasad B, ... Unadkat JD, et al. Transporter expression in non-cancerous and cancerous liver tissue from donors with hepatocellular carcinoma and chronic hepatitis C infection quantified by LC-MS/MS proteomics. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29138286 DOI: 10.1124/Dmd.117.077289 |
0.656 |
|
| 2017 |
Ishida K, Ullah M, Toth B, Juhasz V, Unadkat JD. Successful prediction of in vivo hepatobiliary clearances and hepatic concentrations of rosuvastatin using sandwich-cultured rat hepatocytes, transporter-expressing cell lines, and quantitative proteomics. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29084782 DOI: 10.1016/J.Dmpk.2017.11.106 |
0.406 |
|
| 2017 |
Kumar V, Nguyen TB, Tóth B, Juhasz V, Unadkat JD. Optimization and Application of a Biotinylation Method for Quantification of Plasma Membrane Expression of Transporters in Cells. The Aaps Journal. PMID 28741221 DOI: 10.1208/S12248-017-0121-5 |
0.344 |
|
| 2017 |
Zhang Z, Imperial MZ, Patilea-Vrana GI, Wedagedera J, Gaohua L, Unadkat JD. Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model I: Insights into Factors that Determine Fetal Drug Exposure through Simulations and Sensitivity Analyses. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28588050 DOI: 10.1124/Dmd.117.075192 |
0.37 |
|
| 2017 |
Zhang Z, Unadkat JD. Verification of a Maternal-Fetal Physiologically Based Pharmacokinetic Model for Passive Placental Permeability Drugs. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28049636 DOI: 10.1124/Dmd.116.073957 |
0.366 |
|
| 2016 |
Joshi AA, Vaidya SS, St-Pierre MV, Mikheev AM, Desino KE, Nyandege AN, Audus KL, Unadkat JD, Gerk PM. Placental ABC Transporters: Biological Impact and Pharmaceutical Significance. Pharmaceutical Research. PMID 27644937 DOI: 10.1007/S11095-016-2028-8 |
0.416 |
|
| 2016 |
Prasad B, Johnson K, Billington S, Lee CA, Chung GW, Brown CD, Kelly E, Himmelfarb J, Unadkat JD. Abundance of drug transporters in the human kidney cortex as quantified by LC-MS/MS proteomics. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 27621205 DOI: 10.1124/Dmd.116.072066 |
0.318 |
|
| 2016 |
Wang L, Collins C, Kelly EJ, Chu X, Ray AS, Salphati L, Xiao G, Lee C, Lai Y, Liao M, Mathias A, Evers R, Humphreys G, Hop CE, Kumer SC, ... Unadkat JD, et al. Transporter expression in liver tissue from subjects with alcoholic or hepatitis C cirrhosis quantified by targeted quantitative proteomics. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 27543206 DOI: 10.1124/Dmd.116.071050 |
0.686 |
|
| 2016 |
Patilea-Vrana G, Unadkat JD. Transport vs. metabolism: what determines the pharmacokinetics (PK) and pharmacodynamics (PD) of drugs? Insights from the extended clearance model. Clinical Pharmacology and Therapeutics. PMID 27448198 DOI: 10.1002/Cpt.437 |
0.357 |
|
| 2016 |
Prasad B, Gaedigk A, Vrana M, Gaedigk R, Leeder JS, Salphati L, Chu X, Xiao G, Hop CE, Evers R, Gan L, Unadkat JD. Ontogeny of hepatic drug transporters as quantified by LC-MS/MS proteomics. Clinical Pharmacology and Therapeutics. PMID 27301780 DOI: 10.1002/Cpt.409 |
0.427 |
|
| 2016 |
Endres CJ, Moss AM, Ishida K, Govindarajan R, Unadkat JD. The Role of the Equilibrative Nucleoside Transporter 1 on Tissue and Fetal Distribution of Ribavirin in the Mouse. Biopharmaceutics & Drug Disposition. PMID 27194214 DOI: 10.1002/Bdd.2015 |
0.799 |
|
| 2016 |
Farooq M, Kelly EJ, Unadkat JD. CYP2D6 is inducible by endogenous and exogenous corticosteroids. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26965986 DOI: 10.1124/Dmd.115.069229 |
0.382 |
|
| 2016 |
Zhang Z, Imperial MZ, Patilea‐Vrana GI, Wedagedera J, Lu G, Unadkat JD. Predicting Fetal Exposure To Drugs Throughout Pregnancy Using A Pbpk Model The Faseb Journal. 30. DOI: 10.1096/Fasebj.30.1_Supplement.712.6 |
0.313 |
|
| 2015 |
Liu L, Collier AC, Link JM, Domino KB, Mankoff DA, Eary JF, Spiekerman CF, Hsiao P, Deo AK, Unadkat JD. Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1795-804. PMID 26354948 DOI: 10.1124/Dmd.114.058685 |
0.794 |
|
| 2015 |
Liu H, Yu N, Lu S, Ito S, Zhang X, Prasad B, He E, Lu X, Li Y, Wang F, Xu H, An G, Unadkat JD, Kusuhara H, Sugiyama Y, et al. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2- Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1008-18. PMID 25908246 DOI: 10.1124/Dmd.115.064170 |
0.485 |
|
| 2015 |
Prasad B, Unadkat JD. The concept of fraction of drug transported (ft ) with special emphasis on BBB efflux of CNS and antiretroviral drugs Clinical Pharmacology and Therapeutics. 97: 320-323. PMID 25669655 DOI: 10.1002/Cpt.72 |
0.414 |
|
| 2015 |
Wang L, Prasad B, Salphati L, Chu X, Gupta A, Hop CE, Evers R, Unadkat JD. Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 367-74. PMID 25534768 DOI: 10.1124/Dmd.114.061580 |
0.427 |
|
| 2015 |
Kumar V, Prasad B, Patilea G, Gupta A, Salphati L, Evers R, Hop CE, Unadkat JD. Quantitative transporter proteomics by liquid chromatography with tandem mass spectrometry: addressing methodologic issues of plasma membrane isolation and expression-activity relationship. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 284-8. PMID 25488931 DOI: 10.1124/Dmd.114.061614 |
0.395 |
|
| 2015 |
Mao Q, Unadkat JD. Role of the breast cancer resistance protein (BCRP/ABCG2) in drug transport--an update. The Aaps Journal. 17: 65-82. PMID 25236865 DOI: 10.1208/S12248-014-9668-6 |
0.398 |
|
| 2014 |
Shuster DL, Risler LJ, Prasad B, Calamia JC, Voellinger JL, Kelly EJ, Unadkat JD, Hebert MF, Shen DD, Thummel KE, Mao Q. Identification of CYP3A7 for glyburide metabolism in human fetal livers. Biochemical Pharmacology. 92: 690-700. PMID 25450675 DOI: 10.1016/J.Bcp.2014.09.025 |
0.341 |
|
| 2014 |
Stieger B, Unadkat JD, Prasad B, Langer O, Gali H. Role of (drug) transporters in imaging in health and disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 2007-15. PMID 25249691 DOI: 10.1124/Dmd.114.059873 |
0.43 |
|
| 2014 |
Drozdzik M, Gröer C, Penski J, Lapczuk J, Ostrowski M, Lai Y, Prasad B, Unadkat JD, Siegmund W, Oswald S. Protein abundance of clinically relevant multidrug transporters along the entire length of the human intestine Molecular Pharmaceutics. 11: 3547-3555. PMID 25158075 DOI: 10.1021/Mp500330Y |
0.386 |
|
| 2014 |
Kaspera R, Kirby BJ, Sahele T, Collier AC, Kharasch ED, Unadkat JD, Totah RA. Investigating the contribution of CYP2J2 to ritonavir metabolism in vitro and in vivo. Biochemical Pharmacology. 91: 109-18. PMID 24973543 DOI: 10.1016/J.Bcp.2014.06.020 |
0.351 |
|
| 2014 |
He J, Yu Y, Prasad B, Link J, Miyaoka RS, Chen X, Unadkat JD. PET imaging of Oatp-mediated hepatobiliary transport of [(11)C] rosuvastatin in the rat. Molecular Pharmaceutics. 11: 2745-54. PMID 24957348 DOI: 10.1021/Mp500027C |
0.316 |
|
| 2014 |
Salphati L, Chu X, Chen L, Prasad B, Dallas S, Evers R, Mamaril-Fishman D, Geier EG, Kehler J, Kunta J, Mezler M, Laplanche L, Pang J, Rode A, Soars MG, ... Unadkat JD, et al. Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 1301-13. PMID 24855184 DOI: 10.1124/Dmd.114.057976 |
0.423 |
|
| 2014 |
Deo AK, Borson S, Link JM, Domino K, Eary JF, Ke B, Richards TL, Mankoff DA, Minoshima S, O'Sullivan F, Eyal S, Hsiao P, Maravilla K, Unadkat JD. Activity of P-Glycoprotein, a β-Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 1106-11. PMID 24842892 DOI: 10.2967/Jnumed.113.130161 |
0.754 |
|
| 2014 |
Prasad B, Unadkat JD. Optimized approaches for quantification of drug transporters in tissues and cells by MRM proteomics. The Aaps Journal. 16: 634-48. PMID 24752720 DOI: 10.1208/S12248-014-9602-Y |
0.383 |
|
| 2014 |
Prasad B, Unadkat JD. Comparison of Heavy Labeled (SIL) Peptide versus SILAC Protein Internal Standards for LC-MS/MS Quantification of Hepatic Drug Transporters. International Journal of Proteomics. 2014: 451510. PMID 24719762 DOI: 10.1155/2014/451510 |
0.346 |
|
| 2014 |
He J, Yu Y, Prasad B, Chen X, Unadkat JD. Mechanism of an unusual, but clinically significant, digoxin-bupropion drug interaction. Biopharmaceutics & Drug Disposition. 35: 253-63. PMID 24436229 DOI: 10.1002/Bdd.1890 |
0.391 |
|
| 2014 |
Ke AB, Rostami-Hodjegan A, Zhao P, Unadkat JD. Pharmacometrics in pregnancy: An unmet need. Annual Review of Pharmacology and Toxicology. 54: 53-69. PMID 24392692 DOI: 10.1146/Annurev-Pharmtox-011613-140009 |
0.342 |
|
| 2014 |
Hsiao P, Unadkat JD. Predicting the outer boundaries of P-glycoprotein (P-gp)-based drug interactions at the human blood-brain barrier based on rat studies. Molecular Pharmaceutics. 11: 436-44. PMID 24364805 DOI: 10.1021/Mp400396K |
0.799 |
|
| 2014 |
Hardy KD, Wahlin MD, Papageorgiou I, Unadkat JD, Rettie AE, Nelson SD. Studies on the role of metabolic activation in tyrosine kinase inhibitor-dependent hepatotoxicity: induction of CYP3A4 enhances the cytotoxicity of lapatinib in HepaRG cells. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 162-71. PMID 24191259 DOI: 10.1124/Dmd.113.054817 |
0.313 |
|
| 2014 |
Prasad B, Evers R, Gupta A, Hop CE, Salphati L, Shukla S, Ambudkar SV, Unadkat JD. Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem mass spectroscopy and influence of genotype, age, and sex. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 78-88. PMID 24122874 DOI: 10.1124/Dmd.113.053819 |
0.402 |
|
| 2014 |
Einolf HJ, Chen L, Fahmi OA, Gibson CR, Obach RS, Shebley M, Silva J, Sinz MW, Unadkat JD, Zhang L, Zhao P. Evaluation of various static and dynamic modeling methods to predict clinical CYP3A induction using in vitro CYP3A4 mRNA induction data. Clinical Pharmacology and Therapeutics. 95: 179-88. PMID 23995268 DOI: 10.1038/Clpt.2013.170 |
0.339 |
|
| 2014 |
Ke AB, Nallani SC, Zhao P, Rostami-Hodjegan A, Unadkat JD. Expansion of a PBPK model to predict disposition in pregnant women of drugs cleared via multiple CYP enzymes, including CYP2B6, CYP2C9 and CYP2C19. British Journal of Clinical Pharmacology. 77: 554-70. PMID 23834474 DOI: 10.1111/Bcp.12207 |
0.308 |
|
| 2013 |
Edson KZ, Prasad B, Unadkat JD, Suhara Y, Okano T, Guengerich FP, Rettie AE. Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11. Biochemistry. 52: 8276-85. PMID 24138531 DOI: 10.1021/Bi401208M |
0.336 |
|
| 2013 |
Lee N, Hebert MF, Prasad B, Easterling TR, Kelly EJ, Unadkat JD, Wang J. Effect of gestational age on mRNA and protein expression of polyspecific organic cation transporters during pregnancy. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 2225-32. PMID 24101703 DOI: 10.1124/Dmd.113.054072 |
0.42 |
|
| 2013 |
Ke AB, Eyal S, Chung FS, Link JM, Mankoff DA, Muzi M, Unadkat JD. Modeling cyclosporine A inhibition of the distribution of a P-glycoprotein PET ligand, 11C-verapamil, into the maternal brain and fetal liver of the pregnant nonhuman primate: impact of tissue blood flow and site of inhibition. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 437-46. PMID 23359659 DOI: 10.2967/Jnumed.112.111732 |
0.411 |
|
| 2013 |
Ke AB, Nallani SC, Zhao P, Rostami-Hodjegan A, Isoherranen N, Unadkat JD. A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 801-13. PMID 23355638 DOI: 10.1124/Dmd.112.050161 |
0.354 |
|
| 2013 |
Liu L, Unadkat JD. Interaction between HIV protease inhibitors (PIs) and hepatic transporters in sandwich cultured human hepatocytes: implication for PI-based DDIs. Biopharmaceutics & Drug Disposition. 34: 155-64. PMID 23280499 DOI: 10.1002/Bdd.1832 |
0.449 |
|
| 2013 |
Prasad B, Lai Y, Lin Y, Unadkat JD. Interindividual variability in the hepatic expression of the human breast cancer resistance protein (BCRP/ABCG2): effect of age, sex, and genotype. Journal of Pharmaceutical Sciences. 102: 787-93. PMID 23280364 DOI: 10.1002/Jps.23436 |
0.399 |
|
| 2013 |
Papageorgiou I, Grepper S, Unadkat JD. Induction of hepatic CYP3A enzymes by pregnancy-related hormones: studies in human hepatocytes and hepatic cell lines. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 281-90. PMID 23223499 DOI: 10.1124/Dmd.112.049015 |
0.325 |
|
| 2013 |
Ishida K, Fukao M, Watanabe H, Taguchi M, Miyawaki T, Matsukura H, Uemura O, Zhang Z, Unadkat JD, Hashimoto Y. Effect of salt intake on bioavailability of mizoribine in healthy Japanese males. Drug Metabolism and Pharmacokinetics. 28: 75-80. PMID 22813716 DOI: 10.2133/Dmpk.Dmpk-12-Nt-043 |
0.323 |
|
| 2012 |
Moss AM, Endres CJ, Ruiz-Garcia A, Choi DS, Unadkat JD. Role of the equilibrative and concentrative nucleoside transporters in the intestinal absorption of the nucleoside drug, ribavirin, in wild-type and Ent1(-/-) mice. Molecular Pharmaceutics. 9: 2442-9. PMID 22812541 DOI: 10.1021/Mp200647A |
0.799 |
|
| 2012 |
Liu L, Mugundu GM, Kirby BJ, Samineni D, Desai PB, Unadkat JD. Quantification of human hepatocyte cytochrome P450 enzymes and transporters induced by HIV protease inhibitors using newly validated LC-MS/MS cocktail assays and RT-PCR. Biopharmaceutics & Drug Disposition. 33: 207-17. PMID 22498895 DOI: 10.1002/Bdd.1788 |
0.414 |
|
| 2012 |
Deo AK, Prasad B, Balogh L, Lai Y, Unadkat JD. Interindividual variability in hepatic expression of the multidrug resistance-associated protein 2 (MRP2/ABCC2): quantification by liquid chromatography/tandem mass spectrometry. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 852-5. PMID 22318656 DOI: 10.1124/Dmd.111.043810 |
0.338 |
|
| 2012 |
Hsiao P, Unadkat JD. P-glycoprotein-based loperamide-cyclosporine drug interaction at the rat blood-brain barrier: prediction from in vitro studies and extrapolation to humans. Molecular Pharmaceutics. 9: 629-33. PMID 22316009 DOI: 10.1021/Mp200563A |
0.79 |
|
| 2012 |
Kirby BJ, Collier AC, Kharasch ED, Whittington D, Thummel KE, Unadkat JD. Complex drug interactions of the HIV protease inhibitors 3: effect of simultaneous or staggered dosing of digoxin and ritonavir, nelfinavir, rifampin, or bupropion. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 610-6. PMID 22190694 DOI: 10.1124/Dmd.111.042705 |
0.377 |
|
| 2012 |
Deo A, Borson S, Link J, Eary J, Richards T, Mankoff D, Hsiao P, Minoshima S, Maravilla K, Unadkat J. Activity of P-glycoprotein, an ABC efflux transporter at the blood-brain barrier, is compromised in Alzheimer's disease Alzheimers & Dementia. 8: 698. DOI: 10.1016/J.Jalz.2012.05.1880 |
0.784 |
|
| 2011 |
Kirby BJ, Collier AC, Kharasch ED, Dixit V, Desai P, Whittington D, Thummel KE, Unadkat JD. Complex drug interactions of HIV protease inhibitors 2: in vivo induction and in vitro to in vivo correlation of induction of cytochrome P450 1A2, 2B6, and 2C9 by ritonavir or nelfinavir. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 2329-37. PMID 21930825 DOI: 10.1124/Dmd.111.038646 |
0.405 |
|
| 2011 |
Zolnerciks JK, Booth-Genthe CL, Gupta A, Harris J, Unadkat JD. Substrate- and species-dependent inhibition of P-glycoprotein-mediated transport: implications for predicting in vivo drug interactions. Journal of Pharmaceutical Sciences. 100: 3055-61. PMID 21484807 DOI: 10.1002/Jps.22566 |
0.437 |
|
| 2011 |
Kirby BJ, Collier AC, Kharasch ED, Whittington D, Thummel KE, Unadkat JD. Complex drug interactions of HIV protease inhibitors 1: inactivation, induction, and inhibition of cytochrome P450 3A by ritonavir or nelfinavir. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1070-8. PMID 21406602 DOI: 10.1124/Dmd.110.037523 |
0.415 |
|
| 2010 |
Burnett LA, Blais EM, Unadkat JD, Hille B, Tilley SL, Babcock DF. Testicular expression of Adora3i2 in Adora3 knockout mice reveals a role of mouse A3Ri2 and human A3Ri3 adenosine receptors in sperm. The Journal of Biological Chemistry. 285: 33662-70. PMID 20732875 DOI: 10.1074/Jbc.M110.156075 |
0.304 |
|
| 2010 |
Kirby BJ, Unadkat JD. Impact of ignoring extraction ratio when predicting drug-drug interactions, fraction metabolized, and intestinal first-pass contribution. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 1926-33. PMID 20724498 DOI: 10.1124/Dmd.110.034736 |
0.372 |
|
| 2010 |
Plotnik DA, Emerick LE, Krohn KA, Unadkat JD, Schwartz JL. Different modes of transport for 3H-thymidine, 3H-FLT, and 3H-FMAU in proliferating and nonproliferating human tumor cells. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 1464-71. PMID 20720049 DOI: 10.2967/Jnumed.110.076794 |
0.322 |
|
| 2010 |
Zhou L, Zhang Y, Hebert MF, Unadkat JD, Mao Q. Increased glyburide clearance in the pregnant mouse model. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 1403-6. PMID 20558597 DOI: 10.1124/Dmd.110.033837 |
0.362 |
|
| 2010 |
Zhou L, Naraharisetti SB, Liu L, Wang H, Lin YS, Isoherranen N, Unadkat JD, Hebert MF, Mao Q. Contributions of human cytochrome P450 enzymes to glyburide metabolism. Biopharmaceutics & Drug Disposition. 31: 228-42. PMID 20437462 DOI: 10.1002/Bdd.706 |
0.367 |
|
| 2010 |
Eyal S, Ke B, Muzi M, Link JM, Mankoff DA, Collier AC, Unadkat JD. Regional P-glycoprotein activity and inhibition at the human blood-brain barrier as imaged by positron emission tomography. Clinical Pharmacology and Therapeutics. 87: 579-85. PMID 20336065 DOI: 10.1038/Clpt.2010.11 |
0.776 |
|
| 2010 |
Chung FS, Eyal S, Muzi M, Link JM, Mankoff DA, Kaddoumi A, O'Sullivan F, Hsiao P, Unadkat JD. Positron emission tomography imaging of tissue P-glycoprotein activity during pregnancy in the non-human primate. British Journal of Pharmacology. 159: 394-404. PMID 20002098 DOI: 10.1111/J.1476-5381.2009.00538.X |
0.774 |
|
| 2010 |
Burnett LA, Unadkat JD, Hille B, Tilley S, Babcock DF. How does Adenosine Alter Sperm Motility? Biophysical Journal. 98: 496a-497a. DOI: 10.1016/J.Bpj.2009.12.2704 |
0.325 |
|
| 2010 |
Unadkat JD, Kirby BJ, Endres CJ, Zolnerciks JK. The impact and in vitro to in vivo prediction of transporter-based drug-drug interactions in humans Enzyme- and Transporter-Based Drug-Drug Interactions: Progress and Future Challenges. 517-553. DOI: 10.1007/978-1-4419-0840-7_21 |
0.705 |
|
| 2009 |
Endres CJ, Endres MG, Unadkat JD. Interplay of drug metabolism and transport: a real phenomenon or an artifact of the site of measurement? Molecular Pharmaceutics. 6: 1756-65. PMID 19886641 DOI: 10.1021/Mp9002392 |
0.725 |
|
| 2009 |
Muzi M, Mankoff DA, Link JM, Shoner S, Collier AC, Sasongko L, Unadkat JD. Imaging of cyclosporine inhibition of P-glycoprotein activity using 11C-verapamil in the brain: studies of healthy humans. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 1267-75. PMID 19617341 DOI: 10.2967/Jnumed.108.059162 |
0.456 |
|
| 2009 |
Endres CJ, Moss AM, Govindarajan R, Choi DS, Unadkat JD. The role of nucleoside transporters in the erythrocyte disposition and oral absorption of ribavirin in the wild-type and equilibrative nucleoside transporter 1-/- mice. The Journal of Pharmacology and Experimental Therapeutics. 331: 287-96. PMID 19602549 DOI: 10.1124/Jpet.109.153130 |
0.783 |
|
| 2009 |
Zhang H, Wu X, Naraharisetti SB, Chung F, Whittington D, Mirfazaelian A, Unadkat JD. Pregnancy does not increase CYP3A or P-glycoprotein activity in the non-human primate, Macaca nemestrina. The Journal of Pharmacology and Experimental Therapeutics. 330: 586-95. PMID 19478134 DOI: 10.1124/Jpet.109.153569 |
0.666 |
|
| 2009 |
Zhang Y, Zhou L, Unadkat JD, Mao Q. Effect of pregnancy on nitrofurantoin disposition in mice. Journal of Pharmaceutical Sciences. 98: 4306-15. PMID 19422048 DOI: 10.1002/Jps.21698 |
0.361 |
|
| 2009 |
Eyal S, Chung FS, Muzi M, Link JM, Mankoff DA, Kaddoumi A, O'Sullivan F, Hebert MF, Unadkat JD. Simultaneous PET imaging of P-glycoprotein inhibition in multiple tissues in the pregnant nonhuman primate. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 798-806. PMID 19403878 DOI: 10.2967/Jnumed.108.059360 |
0.411 |
|
| 2009 |
Eyal S, Hsiao P, Unadkat JD. Drug interactions at the blood-brain barrier: fact or fantasy? Pharmacology & Therapeutics. 123: 80-104. PMID 19393264 DOI: 10.1016/J.Pharmthera.2009.03.017 |
0.791 |
|
| 2009 |
Zhang H, Wu X, Chung F, Naraharisetti SB, Whittington D, Mirfazaelian A, Unadkat JD. As in humans, pregnancy increases the clearance of the protease inhibitor nelfinavir in the nonhuman primate Macaca nemestrina. The Journal of Pharmacology and Experimental Therapeutics. 329: 1016-22. PMID 19293388 DOI: 10.1124/Jpet.109.151746 |
0.638 |
|
| 2009 |
Govindarajan R, Leung GP, Zhou M, Tse CM, Wang J, Unadkat JD. Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3. American Journal of Physiology. Gastrointestinal and Liver Physiology. 296: G910-22. PMID 19164483 DOI: 10.1152/Ajpgi.90672.2008 |
0.389 |
|
| 2009 |
Endres CJ, Moss AM, Ke B, Govindarajan R, Choi DS, Messing RO, Unadkat JD. The role of the equilibrative nucleoside transporter 1 (ENT1) in transport and metabolism of ribavirin by human and wild-type or Ent1-/- mouse erythrocytes. The Journal of Pharmacology and Experimental Therapeutics. 329: 387-98. PMID 19164463 DOI: 10.1124/Jpet.108.145854 |
0.772 |
|
| 2008 |
Unadkat JD, Chung F, Sasongko L, Whittington D, Eyal S, Mankoff D, Collier AC, Muzi M, Link J. Rapid solid-phase extraction method to quantify [(11)C]-verapamil, and its [(11)C]-metabolites, in human and macaque plasma. Nuclear Medicine and Biology. 35: 911-7. PMID 19026953 DOI: 10.1016/J.Nucmedbio.2008.08.001 |
0.42 |
|
| 2008 |
Veltkamp SA, Pluim D, van Eijndhoven MA, Bolijn MJ, Ong FH, Govindarajan R, Unadkat JD, Beijnen JH, Schellens JH. New insights into the pharmacology and cytotoxicity of gemcitabine and 2',2'-difluorodeoxyuridine. Molecular Cancer Therapeutics. 7: 2415-25. PMID 18723487 DOI: 10.1158/1535-7163.Mct-08-0137 |
0.31 |
|
| 2008 |
Govindarajan R, Endres CJ, Whittington D, LeCluyse E, Pastor-Anglada M, Tse CM, Unadkat JD. Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G570-80. PMID 18635603 DOI: 10.1152/Ajpgi.00542.2007 |
0.731 |
|
| 2008 |
Zhang H, Wu X, Wang H, Mikheev AM, Mao Q, Unadkat JD. Effect of pregnancy on cytochrome P450 3a and P-glycoprotein expression and activity in the mouse: mechanisms, tissue specificity, and time course. Molecular Pharmacology. 74: 714-23. PMID 18509067 DOI: 10.1124/Mol.107.043851 |
0.65 |
|
| 2008 |
Dickmann LJ, Tay S, Senn TD, Zhang H, Visone A, Unadkat JD, Hebert MF, Isoherranen N. Changes in maternal liver Cyp2c and Cyp2d expression and activity during rat pregnancy. Biochemical Pharmacology. 75: 1677-87. PMID 18342837 DOI: 10.1016/J.Bcp.2008.01.012 |
0.614 |
|
| 2008 |
Gupta A, Mugundu GM, Desai PB, Thummel KE, Unadkat JD. Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1172-80. PMID 18332086 DOI: 10.1124/Dmd.107.018689 |
0.438 |
|
| 2008 |
Kirby BJ, Kalhorn T, Hebert M, Easterling T, Unadkat JD. Sensitive and specific LC-MS assay for quantification of digoxin in human plasma and urine. Biomedical Chromatography : Bmc. 22: 712-8. PMID 18317988 DOI: 10.1002/Bmc.988 |
0.301 |
|
| 2008 |
Hebert MF, Easterling TR, Kirby B, Carr DB, Buchanan ML, Rutherford T, Thummel KE, Fishbein DP, Unadkat JD. Effects of pregnancy on CYP3A and P-glycoprotein activities as measured by disposition of midazolam and digoxin: a University of Washington specialized center of research study. Clinical Pharmacology and Therapeutics. 84: 248-53. PMID 18288078 DOI: 10.1038/Clpt.2008.1 |
0.359 |
|
| 2008 |
Zhou L, Naraharisetti SB, Wang H, Unadkat JD, Hebert MF, Mao Q. The breast cancer resistance protein (Bcrp1/Abcg2) limits fetal distribution of glyburide in the pregnant mouse: an Obstetric-Fetal Pharmacology Research Unit Network and University of Washington Specialized Center of Research Study. Molecular Pharmacology. 73: 949-59. PMID 18079276 DOI: 10.1124/Mol.107.041616 |
0.406 |
|
| 2008 |
Hsiao P, Bui T, Ho RJ, Unadkat JD. In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 481-4. PMID 18057117 DOI: 10.1124/Dmd.107.018176 |
0.798 |
|
| 2008 |
Wang H, Unadkat JD, Mao Q. Hormonal regulation of BCRP expression in human placental BeWo cells. Pharmaceutical Research. 25: 444-52. PMID 17823853 DOI: 10.1007/S11095-007-9432-Z |
0.303 |
|
| 2007 |
Zhang Y, Wang H, Unadkat JD, Mao Q. Breast cancer resistance protein 1 limits fetal distribution of nitrofurantoin in the pregnant mouse. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 2154-8. PMID 17785426 DOI: 10.1124/Dmd.107.018044 |
0.39 |
|
| 2007 |
Govindarajan R, Bakken AH, Hudkins KL, Lai Y, Casado FJ, Pastor-Anglada M, Tse CM, Hayashi J, Unadkat JD. In situ hybridization and immunolocalization of concentrative and equilibrative nucleoside transporters in the human intestine, liver, kidneys, and placenta. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R1809-22. PMID 17761511 DOI: 10.1152/Ajpregu.00293.2007 |
0.352 |
|
| 2007 |
Dixit V, Hariparsad N, Li F, Desai P, Thummel KE, Unadkat JD. Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: implications for predicting clinical drug interactions. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1853-9. PMID 17639026 DOI: 10.1124/Dmd.107.016089 |
0.443 |
|
| 2007 |
Kaddoumi A, Choi SU, Kinman L, Whittington D, Tsai CC, Ho RJ, Anderson BD, Unadkat JD. Inhibition of P-glycoprotein activity at the primate blood-brain barrier increases the distribution of nelfinavir into the brain but not into the cerebrospinal fluid. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1459-62. PMID 17591677 DOI: 10.1124/Dmd.107.016220 |
0.407 |
|
| 2007 |
Gupta A, Unadkat JD, Mao Q. Interactions of azole antifungal agents with the human breast cancer resistance protein (BCRP). Journal of Pharmaceutical Sciences. 96: 3226-35. PMID 17518356 DOI: 10.1002/Jps.20963 |
0.372 |
|
| 2007 |
Dixit V, Hariparsad N, Desai P, Unadkat JD. In vitro LC-MS cocktail assays to simultaneously determine human cytochrome P450 activities. Biopharmaceutics & Drug Disposition. 28: 257-62. PMID 17443647 DOI: 10.1002/Bdd.552 |
0.322 |
|
| 2007 |
Kirby BJ, Unadkat JD. Grapefruit juice, a glass full of drug interactions? Clinical Pharmacology and Therapeutics. 81: 631-3. PMID 17438537 DOI: 10.1038/Sj.Clpt.6100185 |
0.383 |
|
| 2007 |
Unadkat JD, Wara DW, Hughes MD, Mathias AA, Holland DT, Paul ME, Connor J, Huang S, Nguyen BY, Watts DH, Mofenson LM, Smith E, Deutsch P, Kaiser KA, Tuomala RE. Pharmacokinetics and safety of indinavir in human immunodeficiency virus-infected pregnant women. Antimicrobial Agents and Chemotherapy. 51: 783-6. PMID 17158945 DOI: 10.1128/Aac.00420-06 |
0.655 |
|
| 2006 |
Wang H, Wu X, Hudkins K, Mikheev A, Zhang H, Gupta A, Unadkat JD, Mao Q. Expression of the breast cancer resistance protein (Bcrp1/Abcg2) in tissues from pregnant mice: effects of pregnancy and correlations with nuclear receptors. American Journal of Physiology. Endocrinology and Metabolism. 291: E1295-304. PMID 17082346 DOI: 10.1152/Ajpendo.00193.2006 |
0.607 |
|
| 2006 |
Kirby B, Kharasch ED, Thummel KT, Narang VS, Hoffer CJ, Unadkat JD. Simultaneous measurement of in vivo P-glycoprotein and cytochrome P450 3A activities. Journal of Clinical Pharmacology. 46: 1313-9. PMID 17050796 DOI: 10.1177/0091270006292625 |
0.373 |
|
| 2006 |
Lee EW, Lai Y, Zhang H, Unadkat JD. Identification of the mitochondrial targeting signal of the human equilibrative nucleoside transporter 1 (hENT1): implications for interspecies differences in mitochondrial toxicity of fialuridine. The Journal of Biological Chemistry. 281: 16700-6. PMID 16595656 DOI: 10.1074/Jbc.M513825200 |
0.593 |
|
| 2006 |
Hu H, Endres CJ, Chang C, Umapathy NS, Lee EW, Fei YJ, Itagaki S, Swaan PW, Ganapathy V, Unadkat JD. Electrophysiological characterization and modeling of the structure activity relationship of the human concentrative nucleoside transporter 3 (hCNT3). Molecular Pharmacology. 69: 1542-53. PMID 16446384 DOI: 10.1124/Mol.105.018945 |
0.7 |
|
| 2006 |
Hsiao P, Sasongko L, Link JM, Mankoff DA, Muzi M, Collier AC, Unadkat JD. Verapamil P-glycoprotein transport across the rat blood-brain barrier: cyclosporine, a concentration inhibition analysis, and comparison with human data. The Journal of Pharmacology and Experimental Therapeutics. 317: 704-10. PMID 16415090 DOI: 10.1124/Jpet.105.097931 |
0.793 |
|
| 2006 |
Gupta A, Dai Y, Vethanayagam RR, Hebert MF, Thummel KE, Unadkat JD, Ross DD, Mao Q. Cyclosporin A, tacrolimus and sirolimus are potent inhibitors of the human breast cancer resistance protein (ABCG2) and reverse resistance to mitoxantrone and topotecan. Cancer Chemotherapy and Pharmacology. 58: 374-83. PMID 16404634 DOI: 10.1007/S00280-005-0173-6 |
0.336 |
|
| 2006 |
Endres CJ, Hsiao P, Chung FS, Unadkat JD. The role of transporters in drug interactions. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 27: 501-17. PMID 16364611 DOI: 10.1016/J.Ejps.2005.11.002 |
0.793 |
|
| 2006 |
Wang H, Zhou L, Gupta A, Vethanayagam RR, Zhang Y, Unadkat JD, Mao Q. Regulation of BCRP/ABCG2 expression by progesterone and 17beta-estradiol in human placental BeWo cells. American Journal of Physiology. Endocrinology and Metabolism. 290: E798-807. PMID 16352672 DOI: 10.1152/Ajpendo.00397.2005 |
0.305 |
|
| 2006 |
Mathias AA, Maggio-Price L, Lai Y, Gupta A, Unadkat JD. Changes in pharmacokinetics of anti-HIV protease inhibitors during pregnancy: the role of CYP3A and P-glycoprotein. The Journal of Pharmacology and Experimental Therapeutics. 316: 1202-9. PMID 16293714 DOI: 10.1124/Jpet.105.095406 |
0.684 |
|
| 2005 |
Sasongko L, Link JM, Muzi M, Mankoff DA, Yang X, Collier AC, Shoner SC, Unadkat JD. Imaging P-glycoprotein transport activity at the human blood-brain barrier with positron emission tomography. Clinical Pharmacology and Therapeutics. 77: 503-14. PMID 15961982 DOI: 10.1016/J.Clpt.2005.01.022 |
0.421 |
|
| 2005 |
Mathias AA, Hitti J, Unadkat JD. P-glycoprotein and breast cancer resistance protein expression in human placentae of various gestational ages. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 289: R963-9. PMID 15961534 DOI: 10.1152/Ajpregu.00173.2005 |
0.68 |
|
| 2005 |
Winter HR, Unadkat JD. Identification of cytochrome P450 and arylamine N-acetyltransferase isoforms involved in sulfadiazine metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 969-76. PMID 15843491 DOI: 10.1124/Dmd.104.002998 |
0.361 |
|
| 2005 |
Vethanayagam RR, Wang H, Gupta A, Zhang Y, Lewis F, Unadkat JD, Mao Q. Functional analysis of the human variants of breast cancer resistance protein: I206L, N590Y, and D620N. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 697-705. PMID 15743976 DOI: 10.1124/Dmd.105.003657 |
0.307 |
|
| 2005 |
Endres CJ, Unadkat JD. Residues Met89 and Ser160 in the human equilibrative nucleoside transporter 1 affect its affinity for adenosine, guanosine, S6-(4-nitrobenzyl)-mercaptopurine riboside, and dipyridamole. Molecular Pharmacology. 67: 837-44. PMID 15557207 DOI: 10.1124/Mol.104.008102 |
0.694 |
|
| 2005 |
Lai Y, Lee EW, Ton CC, Vijay S, Zhang H, Unadkat JD. Conserved residues F316 and G476 in the concentrative nucleoside transporter 1 (hCNT1) affect guanosine sensitivity and membrane expression, respectively. American Journal of Physiology. Cell Physiology. 288: C39-45. PMID 15456697 DOI: 10.1152/Ajpcell.00192.2004 |
0.631 |
|
| 2004 |
Thadani PV, Strauss JF, Dey SK, Anderson VM, Audus KL, Coats KS, Cross JC, Erlebacher A, Ganapathy V, Linzer DI, Miller RK, Novak DA, Rapaka RS, Sadovsky Y, Salafia CM, ... ... Unadkat J, et al. National Institute on Drug Abuse Conference report on placental proteins, drug transport, and fetal development. American Journal of Obstetrics and Gynecology. 191: 1858-62. PMID 15592265 DOI: 10.1016/J.Ajog.2004.07.059 |
0.33 |
|
| 2004 |
Wade NA, Unadkat JD, Huang S, Shapiro DE, Mathias A, Yasin S, Ciupak G, Watts DH, Delke I, Rathore M, Hitti J, Frenkel L, Samelson R, Smith ME, Mofenson L, et al. Pharmacokinetics and safety of stavudine in HIV-infected pregnant women and their infants: Pediatric AIDS Clinical Trials Group protocol 332. The Journal of Infectious Diseases. 190: 2167-74. PMID 15551216 DOI: 10.1086/425903 |
0.636 |
|
| 2004 |
Mao Q, Conseil G, Gupta A, Cole SP, Unadkat JD. Functional expression of the human breast cancer resistance protein in Pichia pastoris. Biochemical and Biophysical Research Communications. 320: 730-7. PMID 15240109 DOI: 10.1016/J.Bbrc.2004.06.012 |
0.334 |
|
| 2004 |
SenGupta DJ, Unadkat JD. Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep. Biochemical Pharmacology. 67: 453-8. PMID 15037197 DOI: 10.1016/J.Bcp.2003.09.018 |
0.403 |
|
| 2004 |
Gupta A, Zhang Y, Unadkat JD, Mao Q. HIV protease inhibitors are inhibitors but not substrates of the human breast cancer resistance protein (BCRP/ABCG2). The Journal of Pharmacology and Experimental Therapeutics. 310: 334-41. PMID 15007102 DOI: 10.1124/Jpet.104.065342 |
0.426 |
|
| 2004 |
Chang C, Swaan PW, Ngo LY, Lum PY, Patil SD, Unadkat JD. Molecular requirements of the human nucleoside transporters hCNT1, hCNT2, and hENT1. Molecular Pharmacology. 65: 558-70. PMID 14978234 DOI: 10.1124/Mol.65.3.558 |
0.405 |
|
| 2004 |
Unadkat JD, Dahlin A, Vijay S. Placental drug transporters. Current Drug Metabolism. 5: 125-31. PMID 14965255 DOI: 10.2174/1389200043489171 |
0.412 |
|
| 2004 |
Endres CJ, Sengupta DJ, Unadkat JD. Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1. The Biochemical Journal. 380: 131-7. PMID 14759222 DOI: 10.1042/Bj20031880 |
0.699 |
|
| 2004 |
Lai Y, Tse CM, Unadkat JD. Mitochondrial expression of the human equilibrative nucleoside transporter 1 (hENT1) results in enhanced mitochondrial toxicity of antiviral drugs. The Journal of Biological Chemistry. 279: 4490-7. PMID 14607828 DOI: 10.1074/Jbc.M307938200 |
0.363 |
|
| 2002 |
Lai Y, Bakken AH, Unadkat JD. Simultaneous expression of hCNT1-CFP and hENT1-YFP in Madin-Darby canine kidney cells. Localization and vectorial transport studies. The Journal of Biological Chemistry. 277: 37711-7. PMID 12097333 DOI: 10.1074/Jbc.M204986200 |
0.371 |
|
| 2002 |
SenGupta DJ, Lum PY, Lai Y, Shubochkina E, Bakken AH, Schneider G, Unadkat JD. A single glycine mutation in the equilibrative nucleoside transporter gene, hENT1, alters nucleoside transport activity and sensitivity to nitrobenzylthioinosine. Biochemistry. 41: 1512-9. PMID 11814344 DOI: 10.1021/Bi015833W |
0.409 |
|
| 2002 |
Weber A, Kaplan M, Chughtai SA, Cohn LA, Smith AL, Unadkat JD. CYP3A inductive potential of the rifamycins, rifabutin and rifampin, in the rabbit. Biopharmaceutics & Drug Disposition. 22: 157-68. PMID 11745918 DOI: 10.1002/Bdd.268 |
0.382 |
|
| 2001 |
Ngo LY, Patil SD, Unadkat JD. Ontogenic and longitudinal activity of Na(+)-nucleoside transporters in the human intestine. American Journal of Physiology. Gastrointestinal and Liver Physiology. 280: G475-81. PMID 11171631 DOI: 10.1152/Ajpgi.2001.280.3.G475 |
0.407 |
|
| 2000 |
Patil SD, Ngo LY, Unadkat JD. Structure-inhibitory profiles of nucleosides for the human intestinal N1 and N2 Na+-nucleoside transporters. Cancer Chemotherapy and Pharmacology. 46: 394-402. PMID 11127944 DOI: 10.1007/S002800000171 |
0.338 |
|
| 2000 |
Lum PY, Ngo LY, Bakken AH, Unadkat JD. Human intestinal es nucleoside transporter: molecular characterization and nucleoside inhibitory profiles. Cancer Chemotherapy and Pharmacology. 45: 273-8. PMID 10755314 DOI: 10.1007/S002800050040 |
0.401 |
|
| 1999 |
Wang Y, Unadkat JD. Enzymes in addition to CYP3A4 and 3A5 mediate N-demethylation of dextromethorphan in human liver microsomes. Biopharmaceutics & Drug Disposition. 20: 341-346. PMID 10760842 DOI: 10.1002/(Sici)1099-081X(199910)20:7<341::Aid-Bdd195>3.0.Co;2-F |
0.333 |
|
| 1999 |
Wang Y, Livingston E, Patil S, McKinney RE, Bardeguez AD, Gandia J, O'Sullivan MJ, Clax P, Huang S, Unadkat JD. Pharmacokinetics of didanosine in antepartum and postpartum human immunodeficiency virus--infected pregnant women and their neonates: an AIDS clinical trials group study. The Journal of Infectious Diseases. 180: 1536-41. PMID 10515813 DOI: 10.1086/315067 |
0.336 |
|
| 1999 |
Tuntland T, Odinecs A, Pereira CM, Nosbisch C, Unadkat JD. In vitro models to predict the in vivo mechanism, rate, and extent of placental transfer of dideoxynucleoside drugs against human immunodeficiency virus American Journal of Obstetrics and Gynecology. 180: 198-206. PMID 9914604 DOI: 10.1016/S0002-9378(99)70175-4 |
0.393 |
|
| 1998 |
Patil SD, Ngo LY, Glue P, Unadkat JD. Intestinal absorption of ribavirin is preferentially mediated by the Na+-nucleoside purine (N1) transporter. Pharmaceutical Research. 15: 950-2. PMID 9647364 DOI: 10.1023/A:1011945103455 |
0.348 |
|
| 1997 |
Tuntland T, Nosbisch C, Unadkat JD. Effect of pregnancy, mode of administration and neonatal age on the pharmacokinetics of zalcitabine (2', 3'-dideoxycytidine) in the pigtailed macaque (Macaca nemestrina). Journal of Antimicrobial Chemotherapy. 40: 687-693. PMID 9421317 DOI: 10.1093/Jac/40.5.687 |
0.339 |
|
| 1997 |
Chandrasena G, Giltay R, Patil SD, Bakken A, Unadkat JD. Functional expression of human intestinal Na+-dependent and Na+-independent nucleoside transporters in Xenopus laevis oocytes. Biochemical Pharmacology. 53: 1909-18. PMID 9256166 DOI: 10.1016/S0006-2952(97)00170-6 |
0.405 |
|
| 1997 |
Patil SD, Unadkat JD. Sodium-dependent nucleoside transport in the human intestinal brush-border membrane. The American Journal of Physiology. 272: G1314-20. PMID 9227465 DOI: 10.1152/Ajpgi.1997.272.6.G1314 |
0.388 |
|
| 1996 |
Odinecs A, Pereira C, Nosbisch C, Unadkat JD. Prenatal and postpartum pharmacokinetics of stavudine (2',3'-didehydro-3'-deoxythymidine) and didanosine (dideoxyinosine) in pigtailed macaques (Macaca nemestrina). Antimicrobial Agents and Chemotherapy. 40: 2423-2425. PMID 8891157 DOI: 10.1128/Aac.40.10.2423 |
0.395 |
|
| 1996 |
Odinecs A, Nosbisch C, Keller RD, Baughman WL, Unadkat JD. In vivo maternal-fetal pharmacokinetics of stavudine (2',3'-didehydro-3'-deoxythymidine) in pigtailed macaques (Macaca nemestrina). Antimicrobial Agents and Chemotherapy. 40: 196-202. PMID 8787905 DOI: 10.1128/Aac.40.1.196 |
0.363 |
|
| 1996 |
Mitra AK, Thummel KE, Kalhorn TF, Kharasch ED, Unadkat JD, Slattery JT. Inhibition of sulfamethoxazole hydroxylamine formation by fluconazole in human liver microsomes and healthy volunteers. Clinical Pharmacology and Therapeutics. 59: 332-40. PMID 8653996 DOI: 10.1016/S0009-9236(96)80011-7 |
0.361 |
|
| 1996 |
Tuntland T, Nosbisch C, Baughmanc WL, Massarella J, Unadkat JD. Mechanism and rate of placental transfer of zalcitabine (2',3'-dideoxycytidine) in Macaca nemestrina. American Journal of Obstetrics and Gynecology. 174: 856-863. PMID 8633656 DOI: 10.1016/S0002-9378(96)70313-7 |
0.309 |
|
| 1995 |
Pereira CM, Nosbisch C, Baughman WL, Unadkat JD. Effect of zidovudine on transplacental pharmacokinetics of ddI in the pigtailed macaque (Macaca nemestrina) Antimicrobial Agents and Chemotherapy. 39: 343-345. PMID 7726494 DOI: 10.1128/Aac.39.2.343 |
0.312 |
|
| 1994 |
Wang JP, Unadkat JD, McNamara S, O'Sullivan TA, Smith AL, Trager WF, Ramsey B. Disposition of drugs in cystic fibrosis. VI. In vivo activity of cytochrome P450 isoforms involved in the metabolism of (R)-warfarin (including P450 3A4) is not enhanced in cystic fibrosis. Clinical Pharmacology and Therapeutics. 55: 528-34. PMID 8181197 DOI: 10.1038/Clpt.1994.66 |
0.328 |
|
| 1994 |
Tuntland T, Ravasco RJ, al-Habet S, Unadkat JD. Efflux of zidovudine and 2',3'-dideoxyinosine out of the cerebrospinal fluid when administered alone and in combination to Macaca nemestrina. Pharmaceutical Research. 11: 312-7. PMID 8165194 DOI: 10.1023/A:1018928013044 |
0.378 |
|
| 1994 |
Hutabarat RM, Smith AL, Unadkat JD. Disposition of drugs in cystic fibrosis. VII. Acetylation of sulfamethoxazole in blood cells: in vitro-in vivo correlation and characterization of its kinetics of acetylation in lymphocytes. Clinical Pharmacology and Therapeutics. 55: 427-33. PMID 8162669 DOI: 10.1038/Clpt.1994.52 |
0.309 |
|
| 1994 |
Pereira CM, Nosbisch C, Winter HR, Baughman WL, Unadkat JD. Transplacental pharmacokinetics of dideoxyinosine in pigtailed macaques Antimicrobial Agents and Chemotherapy. 38: 781-786. PMID 8031046 DOI: 10.1128/Aac.38.4.781 |
0.332 |
|
| 1994 |
Qian M, Chandrasena G, Ho RJY, Unadkat JD. Comparison of rates of intracellular metabolism of zidovudine in human and primate peripheral blood mononuclear cells. Antimicrobial Agents and Chemotherapy. 38: 2398-2403. PMID 7840577 DOI: 10.1128/Aac.38.10.2398 |
0.357 |
|
| 1994 |
Unadkat JD, Pereira CM. Maternal-fetal transfer and fetal toxicity of anti-HIV drugs Placenta. 15: 67-82. DOI: 10.1016/S0143-4004(05)80336-4 |
0.304 |
|
| 1993 |
Lopez-Anaya A, Unadkat JD, Calkins DF, Smith AL. Effect of age on distribution of zidovudine (azidothymidine) into the cerebrospinal fluid of Macaca nemestrina. Pharmaceutical Research. 10: 1338-40. PMID 8234173 DOI: 10.1023/A:1018977915364 |
0.322 |
|
| 1992 |
Pereira C, Nosbisch C, Winter H, Baughmans WL, Unadkat JD. Transplacental pharmacokinetics of dideoxvinosine (ddI) Placenta. 13: A50. DOI: 10.1016/0143-4004(92)90162-M |
0.334 |
|
| 1991 |
O'Sullivan TA, Bauer LA, Horn JR, Zierler BK, Strandness DE, Williams-Warren J, Smith AL, Unadkat JD. Disposition of drugs in cystic fibrosis. II. Hepatic blood flow. Clinical Pharmacology and Therapeutics. 50: 450-5. PMID 1914381 DOI: 10.1038/Clpt.1991.163 |
0.316 |
|
| 1991 |
Lopez-Anaya A, Unadkat JD, Schumann LA, Smith AL. Pharmacokinetics of Zidovudine (Azidothymidine). III. Effect of Pregnancy Jaids Journal of Acquired Immune Deficiency Syndromes. 4: 64???68. DOI: 10.1097/00126334-199101000-00009 |
0.323 |
|
| 1987 |
Carpenter RL, Eger RI, Johnson BH, Unadkat JD, Sheiner LB. Does the duration of anesthetic administration affect the pharmacokinetics or metabolism of inhaled anesthetics in humans? Anesthesia and Analgesia. 66: 1-8. PMID 3800013 DOI: 10.1213/00000539-198701000-00001 |
0.322 |
|
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