Serena Spudich - Publications

Affiliations: 
Medicine Yale University, New Haven, CT 
Area:
Medicine and Surgery, Neuroscience Biology, General

157 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ament SA, Campbell RR, Lobo MK, Receveur JP, Agrawal K, Borjabad A, Byrareddy SN, Chang L, Clarke D, Emani P, Gabuzda D, Gaulton KJ, Giglio M, Giorgi FM, Gok B, ... ... Spudich S, et al. The single-cell opioid responses in the context of HIV (SCORCH) consortium. Molecular Psychiatry. PMID 38879719 DOI: 10.1038/s41380-024-02620-7  0.549
2024 Wagner TA, Tierney C, Huang S, Nichols S, Malee KM, Montañez NA, Coletti A, Spiegel HML, Krotje C, Bone F, Wilkins M, Abuogi L, Purswani M, Bearden A, Wiznia A, ... ... Spudich S, et al. Prevalence of detectable HIV-DNA and -RNA in cerebrospinal fluid of youth with perinatal HIV and impaired cognition on antiretroviral therapy. Aids (London, England). PMID 38814693 DOI: 10.1097/QAD.0000000000003937  0.596
2024 Hu Z, Cinque P, Dravid A, Hagberg L, Yilmaz A, Zetterberg H, Fuchs D, Gostner J, Blennow K, Spudich SS, Kincer L, Zhou S, Joseph S, Swanstrom R, Price RW, et al. Changes in Cerebrospinal Fluid Proteins across the Spectrum of Untreated and Treated Chronic HIV-1 Infection. Biorxiv : the Preprint Server For Biology. PMID 38746436 DOI: 10.1101/2024.05.03.592451  0.586
2024 Ocampo FF, Sacdalan C, Pinyakorn S, Paudel M, Wansom T, Poltubtim N, Sriplienc S, Phanuphak N, Paul R, Hsu D, Colby D, Trautmann L, Spudich S, Chan P. Neuropsychiatric and Laboratory Outcomes of Hepatitis C Treatment in an Early-Treated HIV Cohort in Thailand. Research Square. PMID 38645141 DOI: 10.21203/rs.3.rs-4186965/v1  0.311
2024 Wang M, Yoon J, Reisert H, Das B, Orlinick B, Chiarella J, Halvas EK, Mellors J, Pang AP, Barakat LA, Fikrig M, Cyktor J, Kluger Y, Spudich S, Corley MJ, et al. HIV-1-infected T cell clones are shared across cerebrospinal fluid and blood during ART. Jci Insight. 9. PMID 38587074 DOI: 10.1172/jci.insight.176208  0.56
2024 Holroyd KB, Han WM, Apornpong T, Trautmann L, Gatechompol S, Hiransuthikul A, Ubolyam S, Sacdalan C, Sriplienchan S, Kanaprach R, Kerr S, Avihingsanon A, Spudich S, Chan P. Framingham risk score based vascular outcomes in acute versus chronic HIV cohorts after 6 years of ART. Hiv Medicine. PMID 38383057 DOI: 10.1111/hiv.13621  0.455
2023 Chan P, Moreland S, Sacdalan C, Kroon E, Colby D, Sriplienchan S, Pinyakorn S, Phanuphak N, Jagodzinski L, Valcour V, Vasan S, Paul R, Trautmann L, Spudich S. Cerebrospinal fluid pleocytosis is associated with HIV-1 neuroinvasion during acute infection. Aids (London, England). PMID 37916464 DOI: 10.1097/QAD.0000000000003777  0.658
2023 Albalawi YA, Shull T, Virdi A, Subra C, Mitchell J, Slike BM, Jian N, Krebs SJ, Sacdalan C, Ratnaratorn N, Hsu DC, Phanuphak N, Spudich S, Trautmann L, Al-Harthi L. CD4dimCD8bright T cells are inversely associated with neuro-inflammatory markers among people living with HIV. Aids (London, England). PMID 37792358 DOI: 10.1097/QAD.0000000000003743  0.538
2023 Letendre SL, Chen H, McKhann A, Roa J, Vecchio A, Daar ES, Berzins B, Hunt PW, Marra CM, Campbell TB, Coombs RW, Ma Q, Swaminathan S, Macatangay BJC, Morse GD, ... ... Spudich S, et al. Antiretroviral Therapy Intensification for Neurocognitive Impairment in HIV. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 37183889 DOI: 10.1093/cid/ciad265  0.613
2023 Joseph SB, Gianella S, Burdo TH, Cinque P, Gisslen M, Letendre S, Nath A, Morgello S, Ndhlovu LC, Spudich S. Biotypes of Central Nervous System Complications in People With Human Immunodeficiency Virus: Virology, Immunology, and Neuropathology. The Journal of Infectious Diseases. 227: S3-S15. PMID 36930640 DOI: 10.1093/infdis/jiac370  0.466
2023 Kincer LP, Schnell G, Swanstrom R, Miller MB, Spudich S, Eron JJ, Price RW, Joseph SB. HIV-1 is Transported into the Central Nervous System by Trafficking Infected Cells. Pathogens & Immunity. 7: 131-142. PMID 36865569 DOI: 10.20411/pai.v7i2.524  0.573
2023 Bolzenius J, Sacdalan C, Ndhlovu LC, Sailasuta N, Trautmann L, Tipsuk S, Crowell TA, Suttichom D, Colby DJ, Phanuphak N, Chan P, Premeaux T, Kroon E, Vasan S, Hsu DC, ... ... Spudich S, et al. Brain volumetrics differ by fiebig stage in acute HIV infection. Aids (London, England). PMID 36723491 DOI: 10.1097/QAD.0000000000003496  0.618
2023 Kincer LP, Joseph SB, Gilleece MM, Hauser BM, Sizemore S, Zhou S, Di Germanio C, Zetterberg H, Fuchs D, Deeks SG, Spudich S, Gisslen M, Price RW, Swanstrom R. Rebound HIV-1 in cerebrospinal fluid after antiviral therapy interruption is mainly clonally amplified R5 T cell-tropic virus. Nature Microbiology. 8: 260-271. PMID 36717718 DOI: 10.1038/s41564-022-01306-6  0.54
2022 Paul R, Cho K, Bolzenius J, Sacdalan C, Ndhlovu LC, Trautmann L, Krebs S, Tipsuk S, Crowell TA, Suttichom D, Colby DJ, Premeaux TA, Phanuphak N, Chan P, Kroon E, ... ... Spudich S, et al. Individual differences in CD4/CD8 T-cell ratio trajectories and associated risk profiles modeled from acute HIV infection. Psychosomatic Medicine. PMID 36162059 DOI: 10.1097/PSY.0000000000001129  0.416
2022 Le LT, Price RW, Gisslén M, Zetterberg H, Emu B, Fabre R, Christian P, Andersen S, Spudich S, Vassallo M. Correlation between CD4/CD8 ratio and neurocognitive performance during early HIV infection. Hiv Medicine. PMID 36134890 DOI: 10.1111/hiv.13411  0.442
2022 Killingsworth L, Spudich S. Neuropathogenesis of HIV-1: insights from across the spectrum of acute through long-term treated infection. Seminars in Immunopathology. PMID 35882661 DOI: 10.1007/s00281-022-00953-5  0.654
2022 Farhadian SF, Lindenbaum O, Zhao J, Corley MJ, Im Y, Walsh H, Vecchio A, Garcia-Milian R, Chiarella J, Chintanaphol M, Calvi R, Wang G, Ndhlovu LC, Yoon J, Trotta D, ... ... Spudich S, et al. HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART. Jci Insight. 7. PMID 35801589 DOI: 10.1172/jci.insight.160267  0.621
2022 Chan P, Yoon B, Colby D, Kroon E, Sacdalan C, Sriplienchan S, Pinyakorn S, Ananworanich J, Valcour V, Vasan S, Hsu D, Phanuphak N, Paul R, Spudich S. Immunological, Cognitive and Psychiatric Outcomes after Initiating EFV- and DTG-based Antiretroviral Therapy during Acute HIV Infection. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 35687498 DOI: 10.1093/cid/ciac466  0.577
2022 Chan P, Spudich S. HIV Compartmentalization in the CNS and Its Impact in Treatment Outcomes and Cure Strategies. Current Hiv/Aids Reports. 19: 207-216. PMID 35536438 DOI: 10.1007/s11904-022-00605-1  0.527
2022 Collora JA, Liu R, Pinto-Santini D, Ravindra N, Ganoza C, Lama JR, Alfaro R, Chiarella J, Spudich S, Mounzer K, Tebas P, Montaner LJ, van Dijk D, Duerr A, Ho YC. Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones. Immunity. PMID 35320704 DOI: 10.1016/j.immuni.2022.03.004  0.572
2021 Sharma V, Creegan M, Tokarev A, Hsu D, Slike BM, Sacdalan C, Chan P, Spudich S, Ananworanich J, Eller MA, Krebs SJ, Vasan S, Bolton DL. Cerebrospinal fluid CD4+ T cell infection in humans and macaques during acute HIV-1 and SHIV infection. Plos Pathogens. 17: e1010105. PMID 34874976 DOI: 10.1371/journal.ppat.1010105  0.58
2021 Ulfhammer G, Edén A, Antinori A, Brew BJ, Calcagno A, Cinque P, De Zan V, Hagberg L, Lin A, Nilsson S, Oprea C, Pinnetti C, Spudich S, Trunfio M, Winston A, et al. Cerebrospinal Fluid viral load across the spectrum of untreated HIV-1 infection: a cross-sectional multi-center study. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 34747481 DOI: 10.1093/cid/ciab943  0.627
2021 Longino AA, Paul R, Wang Y, Lama JR, Brandes P, Ruiz E, Correa C, Keating S, Spudich SS, Pilcher C, Vecchio A, Pasalar S, Bender Ignacio RA, Valdez R, Dasgupta S, et al. HIV disease dynamics, markers of inflammation and CNS injury during primary HIV infection and their relationship to cognitive performance. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 34629415 DOI: 10.1097/QAI.0000000000002832  0.599
2021 Corley MJ, Sacdalan C, Pang AP, Chomchey N, Ratnaratorn N, Valcour V, Kroon E, Cho KS, Belden AC, Colby D, Robb M, Hsu D, Spudich S, Paul R, Vasan S, et al. Abrupt and altered cell-type specific DNA methylation profiles in blood during acute HIV infection persists despite prompt initiation of ART. Plos Pathogens. 17: e1009785. PMID 34388205 DOI: 10.1371/journal.ppat.1009785  0.543
2021 Weiss JJ, Spudich S, Barakat L. VZV myelitis with secondary HIV CSF escape. Bmj Case Reports. 14. PMID 34187795 DOI: 10.1136/bcr-2021-241738  0.585
2021 Weiss JJ, Calvi R, Naganawa M, Toyonaga T, Farhadian SF, Chintanaphol M, Chiarella J, Zheng MQ, Ropchan J, Huang Y, Pietrzak RH, Carson RE, Spudich S. Preliminary in vivo Evidence of Reduced Synaptic Density in HIV despite Antiretroviral Therapy. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 34050746 DOI: 10.1093/cid/ciab484  0.516
2021 Gisslen M, Keating SM, Spudich S, Arechiga V, Stephenson S, Zetterberg H, Di Germanio C, Blennow K, Fuchs D, Hagberg L, Norris PJ, Peterson J, Shacklett BL, Yiannoutsos CT, Price RW. Compartmentalization of cerebrospinal fluid inflammation across the spectrum of untreated HIV-1 infection, central nervous system injury and viral suppression. Plos One. 16: e0250987. PMID 33983973 DOI: 10.1371/journal.pone.0250987  0.608
2021 Chan P, Spudich S. Investigating vascular diseases in people living with HIV by nuclear imaging. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. PMID 33884573 DOI: 10.1007/s12350-021-02613-x  0.435
2021 Chan P, Kerr SJ, Kroon E, Colby D, Sacdalan C, Hellmuth J, Reiss P, Vasan S, Ananworanich J, Valcour V, Spudich S, Paul R. Cognitive trajectories after treatment in acute HIV infection. Aids (London, England). PMID 33534200 DOI: 10.1097/QAD.0000000000002831  0.563
2020 Handoko R, Chan P, Jagodzinski L, Pinyakorn S, Ubolyam S, Phanuphak N, Sacdalan C, Kroon E, Dumrongpisutikul N, Paul R, Valcour V, Ananworanich J, Vasan S, Spudich S. Minimal detection of cerebrospinal fluid escape after initiation of antiretroviral therapy in acute HIV-1 infection. Aids (London, England). PMID 33306551 DOI: 10.1097/QAD.0000000000002786  0.683
2020 Kroon EDMB, Ananworanich J, Pagliuzza A, Rhodes A, Phanuphak N, Trautmann L, Mitchell JL, Chintanaphol M, Intasan J, Pinyakorn S, Benjapornpong K, Chang JJ, Colby DJ, Chomchey N, Fletcher JLK, ... ... Spudich S, et al. A randomized trial of vorinostat with treatment interruption after initiating antiretroviral therapy during acute HIV-1 infection. Journal of Virus Eradication. 6: 100004. PMID 33251022 DOI: 10.1016/J.Jve.2020.100004  0.683
2020 Handoko R, Colby DJ, Kroon E, Sacdalan C, de Souza M, Pinyakorn S, Prueksakaew P, Munkong C, Ubolyam S, Akapirat S, Chiarella J, Krebs S, Sereti I, Valcour V, Paul R, ... ... Spudich S, et al. Determinants of suboptimal CD4 T cell recovery after antiretroviral therapy initiation in a prospective cohort of acute HIV-1 infection. Journal of the International Aids Society. 23: e25585. PMID 32949118 DOI: 10.1002/Jia2.25585  0.634
2020 Hellmuth J, Muccini C, Colby DJ, Kroon E, de Souza M, Crowell TA, Chan P, Sacdalan C, Intasan J, Benjapornpong K, Tipsuk S, Puttamaswin S, Chomchey N, Valcour V, Sarnecki M, ... ... Spudich S, et al. Central nervous system safety during brief analytic treatment interruption of antiretroviral therapy within four HIV remission trials: an observational study in acutely treated people living with HIV. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 32916708 DOI: 10.1093/Cid/Ciaa1344  0.664
2020 Winston A, Spudich S. Cognitive disorders in people living with HIV. The Lancet. Hiv. 7: e504-e513. PMID 32621876 DOI: 10.1016/S2352-3018(20)30107-7  0.535
2020 Farhadian S, Glick LR, Vogels CBF, Thomas J, Chiarella J, Casanovas-Massana A, Zhou J, Odio C, Vijayakumar P, Geng B, Fournier J, Bermejo S, Fauver JR, Alpert T, Wyllie AL, ... ... Spudich S, et al. Acute encephalopathy with elevated CSF inflammatory markers as the initial presentation of COVID-19. Bmc Neurology. 20: 248. PMID 32552792 DOI: 10.1186/S12883-020-01812-2  0.351
2020 Liu R, Yeh YJ, Varabyou A, Collora JA, Sherrill-Mix S, Talbot CC, Mehta S, Albrecht K, Hao H, Zhang H, Pollack RA, Beg SA, Calvi RM, Hu J, Durand CM, ... ... Spudich S, et al. Single-cell transcriptional landscapes reveal HIV-1-driven aberrant host gene transcription as a potential therapeutic target. Science Translational Medicine. 12. PMID 32404504 DOI: 10.1126/Scitranslmed.Aaz0802  0.654
2020 Chintanaphol M, Sacdalan C, Pinyakorn S, Rerknimitr R, Ridtitid W, Prueksapanich P, Sereti I, Schuetz A, Crowell TA, Colby DJ, Robb ML, Phanuphak N, Ananworanich J, Spudich SS, Kroon E. Feasibility and safety of research sigmoid colon biopsy in a cohort of Thai men who have sex with men with acute HIV-1. Journal of Virus Eradication. 6: 7-10. PMID 32175085  0.52
2020 Philippi CL, Reyna L, Nedderman L, Chan P, Samboju V, Chang K, Phanuphak N, Ratnaratorn N, Hellmuth J, Benjapornpong K, Dumrongpisutikul N, Pothisri M, Robb ML, Ananworanich J, Spudich S, et al. Resting-state neural signatures of depressive symptoms in acute HIV. Journal of Neurovirology. PMID 31989446 DOI: 10.1007/S13365-020-00826-3  0.414
2020 Peluso MJ, Colby DJ, Pinyakorn S, Ubolyam S, Intasan J, Trichavaroj R, Chomchey N, Prueksakaew P, Slike BM, Krebs SJ, Jian N, Robb ML, Phanuphak P, Phanuphak N, Spudich S, et al. Liver function test abnormalities in a longitudinal cohort of Thai individuals treated since acute HIV infection. Journal of the International Aids Society. 23: e25444. PMID 31953919 DOI: 10.1002/Jia2.25444  0.77
2020 Chan P, Goh O, Kroon E, Colby D, Sacdalan C, Pinyakorn S, Prueksakaew P, Reiss P, Ananworanich J, Valcour V, Spudich S, Paul R. Neuropsychiatric outcomes before and after switching to dolutegravir-based therapy in an acute HIV cohort. Aids Research and Therapy. 17: 1. PMID 31907064 DOI: 10.1186/S12981-019-0257-8  0.625
2019 Farhadian SF, Mistry H, Kirchwey T, Chiarella J, Calvi R, Chintanaphol M, Patel P, Landry ML, Robertson K, Spudich SS. Markers of CNS Injury in Adults Living With HIV With CSF HIV Not Detected vs Detected <20 Copies/mL. Open Forum Infectious Diseases. 6: ofz528. PMID 31893212 DOI: 10.1093/Ofid/Ofz528  0.522
2019 Winston A, Antinori A, Cinque P, Fox HS, Gisslen M, Henrich TJ, Letendre S, Persaud D, Price RW, Spudich S. Defining cerebrospinal fluid HIV RNA escape: editorial review AIDS. Aids (London, England). 33: S107-S111. PMID 31790376 DOI: 10.1097/Qad.0000000000002252  0.608
2019 Spudich S, Peterson J, Fuchs D, Price RW, Gisslen M. Potential for early antiretroviral therapy to reduce central nervous system HIV-1 persistence. Aids (London, England). 33: S135-S144. PMID 31789814 DOI: 10.1097/Qad.0000000000002326  0.71
2019 Spudich S, Clements JE. HIV persistence in the central nervous system during antiretroviral therapy: evidence and implications. Aids (London, England). 33: S103-S106. PMID 31789813 DOI: 10.1097/Qad.0000000000002439  0.647
2019 Kallianpur KJ, Jahanshad N, Sailasuta N, Benjapornpong K, Chan P, Pothisri M, Dumrongpisutikul N, Laws E, Ndhlovu LC, Clifford KM, Paul R, Jagodzinski L, Krebs S, Ananworanich J, Spudich S, et al. Regional brain volumetric changes despite two years of treatment initiated during acute HIV infection. Aids (London, England). PMID 31725432 DOI: 10.1097/Qad.0000000000002436  0.603
2019 OʼMeara T, Kong Y, Chiarella J, Price RW, Chaudhury R, Liu X, Spudich S, Robertson K, Emu B, Lu L. Exosomal MicroRNAs Associate With Neuropsychological Performance in Individuals With HIV Infection on Antiretroviral Therapy. Journal of Acquired Immune Deficiency Syndromes (1999). 82: 514-522. PMID 31714431 DOI: 10.1097/Qai.0000000000002187  0.606
2019 Patel PB, Apornpong T, Puthanakit T, Thongpibul K, Kosalaraksa P, Hansudewechakul R, Kanjanavanit S, Ngampiyaskul C, Luesomboon W, Wongsawat J, Sun LP, Chettra K, Saphonn V, Mellins CA, Malee K, ... Spudich S, et al. Trajectory Analysis of Cognitive Outcomes in Children With Perinatal HIV. The Pediatric Infectious Disease Journal. 38: 1038-1044. PMID 31568142 DOI: 10.1097/Inf.0000000000002427  0.418
2019 Tovanabutra S, Sirijatuphat R, Pham PT, Bonar L, Harbolick EA, Bose M, Song H, Chang D, Oropeza C, O'Sullivan AM, Balinang J, Kroon E, Colby DJ, Sacdalan C, Hellmuth J, ... ... Spudich S, et al. Deep Sequencing Reveals Central Nervous System Compartmentalization in Multiple Transmitted/Founder Virus Acute HIV-1 Infection. Cells. 8. PMID 31443253 DOI: 10.3390/Cells8080902  0.695
2019 Handoko R, Spudich S. Treatment of Central Nervous System Manifestations of HIV in the Current Era. Seminars in Neurology. 39: 391-398. PMID 31378874 DOI: 10.1055/S-0039-1688915  0.677
2019 Spudich S, Robertson KR, Bosch RJ, Gandhi RT, Cyktor JC, Mar H, Macatangay BJ, Lalama CM, Rinaldo C, Collier AC, Godfrey C, Eron JJ, McMahon D, Jacobs JL, Koontz D, et al. Persistent HIV-infected cells in cerebrospinal fluid are associated with poorer neurocognitive performance. The Journal of Clinical Investigation. 130. PMID 31305262 DOI: 10.1172/Jci127413  0.644
2019 Goh OQ, Colby DJ, Pinyakorn S, Sacdalan C, Kroon E, Chan P, Chomchey N, Kanaprach R, Prueksakaew P, Suttichom D, Trichavaroj R, Spudich S, Robb ML, Phanuphak P, Phanuphak N, et al. Switch to dolutegravir is well tolerated in Thais with HIV infection. Journal of the International Aids Society. 22: e25324. PMID 31294931 DOI: 10.1002/Jia2.25324  0.681
2019 Chan P, Dumrongpisutikul N, Subra C, Colby DJ, Kroon E, Fletcher J, Sacdalan C, Phanuphak N, Valcour V, Ananworanich J, Trautmann L, Spudich S. Neurosyphilis during Acute HIV Infection: A CNS Immunologic and Virologic Characterization. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 31180994 DOI: 10.1097/Qai.0000000000002114  0.691
2019 Sandhu MR, Rutledge R, Grant M, Mahajan A, Spudich S. Slowly progressive fatal PML-IRIS following antiretroviral initiation at CD4+ nadir of 350 cells/mm despite CD4+ cell count rise to 900 cells/mm. International Journal of Std & Aids. 956462419835966. PMID 31046614 DOI: 10.1177/0956462419835966  0.427
2019 Julg B, Dee L, Ananworanich J, Barouch DH, Bar K, Caskey M, Colby DJ, Dawson L, Dong KL, Dubé K, Eron J, Frater J, Gandhi RT, Geleziunas R, Goulder P, ... ... Spudich S, et al. Recommendations for analytical antiretroviral treatment interruptions in HIV research trials-report of a consensus meeting. The Lancet. Hiv. PMID 30885693 DOI: 10.1016/S2352-3018(19)30052-9  0.541
2019 Srinivas N, Joseph SB, Robertson K, Kincer LP, Menezes P, Adamson L, Schauer AP, Blake KH, White N, Sykes C, Luciw P, Eron JJ, Forrest A, Price R, Spudich S, et al. Predicting efavirenz concentrations in the brain tissue of HIV-infected individuals and exploring their relationship to neurocognitive impairment. Clinical and Translational Science. PMID 30675981 DOI: 10.1111/Cts.12620  0.423
2019 Hellmuth J, Slike BM, Sacdalan C, Best J, Kroon E, Phanuphak N, Fletcher JLK, Prueksakaew P, Jagodzinski LL, Valcour V, Robb M, Ananworanich J, Allen IE, Krebs SJ, Spudich S, et al. Very early ART initiation during acute HIV infection is associated with normalization of cerebrospinal fluid but not plasma markers of immune activation. The Journal of Infectious Diseases. PMID 30668739 DOI: 10.1093/Infdis/Jiz030  0.693
2019 Yilmaz A, Fuchs D, Price RW, Spudich S, Blennow K, Zetterberg H, Gisslén M. Cerebrospinal Fluid Concentrations of the Synaptic Marker Neurogranin in Neuro-HIV and Other Neurological Disorders. Current Hiv/Aids Reports. PMID 30649659 DOI: 10.1007/S11904-019-00420-1  0.595
2019 Gisslén M, Heslegrave A, Veleva E, Yilmaz A, Andersson LM, Hagberg L, Spudich S, Fuchs D, Price RW, Zetterberg H. CSF concentrations of soluble TREM2 as a marker of microglial activation in HIV-1 infection. Neurology(R) Neuroimmunology & Neuroinflammation. 6: e512. PMID 30568991 DOI: 10.1212/Nxi.0000000000000512  0.673
2019 Mitchell B, Laws E, Paul R, Vasan S, Kroon E, Valcour V, Spudich S, Shikuma C, Ananworanich J, Ndhlovu L. A modified TZM-bl assay (MoCo-TZA) documents replication-competent HIV in circulating monocytes despite 2 years of antiretroviral therapy initiated early during acute infection Journal of Virus Eradication. 5: 35-36. DOI: 10.1016/S2055-6640(20)30167-9  0.657
2019 Reyna L, Dumrongpisutikul N, Chan P, Phanuphak N, Ratnaratorn N, Pothisri M, Samboju V, Robb M, Benjapornpong K, Spudich S, Valcour V, Paul R, Philippi C. T146. Altered Resting-State Connectivity of the Amygdala in Acute HIV Biological Psychiatry. 85: S185-S186. DOI: 10.1016/J.Biopsych.2019.03.469  0.549
2018 Joseph SB, Kincer LP, Bowman NM, Evans C, Vinikoor MJ, Lippincott CK, Gisslén M, Spudich S, Menezes P, Robertson K, Archin N, Kashuba A, Eron JJ, Price RW, Swanstrom R. HIV-1 RNA Detected in the CNS after Years of Suppressive Antiretroviral Therapy Can Originate from a Replicating CNS Reservoir or Clonally Expanded Cells. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 30561541 DOI: 10.1093/Cid/Ciy1066  0.603
2018 Silverman A, O'Meara T, Le L, Robertson K, Spudich S. Residency Training: Progressive gait difficulty and incontinence in a 40-year-old man with HIV. Neurology. 91: 1065-1070. PMID 30510020 DOI: 10.1212/Wnl.0000000000006619  0.528
2018 Farhadian SF, Mehta SS, Zografou C, Robertson K, Price RW, Pappalardo J, Chiarella J, Hafler DA, Spudich SS. Single-cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid during virologically suppressed HIV. Jci Insight. 3. PMID 30232286 DOI: 10.1172/Jci.Insight.121718  0.556
2018 Chintanaphol M, Sacdalan C, Chottanapund S, Pinyakorn S, Buranapraditkun S, Crowell TA, Kroon E, Manasnayakorn S, Chipman JG, Schacker TW, Michael N, Phanuphak N, Spudich SS, Colby DJ, Ananworanich J. Brief Report: Safety and Tolerability of Inguinal Lymph Node Biopsy in Individuals With Acute HIV Infection in Thailand. Journal of Acquired Immune Deficiency Syndromes (1999). 79: 244-248. PMID 30212436 DOI: 10.1097/QAI.0000000000001780  0.527
2018 Samboju V, Philippi CL, Chan P, Cobigo Y, Fletcher JLK, Robb M, Hellmuth J, Benjapornpong K, Dumrongpisutikul N, Pothisri M, Paul R, Ananworanich J, Spudich S, Valcour V. Structural and functional brain imaging in acute HIV. Neuroimage. Clinical. 20: 327-335. PMID 30101063 DOI: 10.1016/J.Nicl.2018.07.024  0.656
2018 D'Antoni ML, Byron MM, Chan P, Sailasuta N, Sacdalan C, Sithinamsuwan P, Tipsuk S, Pinyakorn S, Kroon E, Slike BM, Krebs SJ, Khadka VS, Chalermchai T, Kallianpur KJ, Robb M, ... Spudich S, et al. Normalization of Soluble CD163 after Institution of Antiretroviral Therapy During Acute HIV Infection Tracks with Fewer Neurological Abnormalities. The Journal of Infectious Diseases. PMID 29868826 DOI: 10.1093/Infdis/Jiy337  0.657
2018 Patel PB, Spudich SS. Global Health Neurology: HIV/AIDS. Seminars in Neurology. 38: 238-246. PMID 29791950 DOI: 10.1055/s-0038-1649334  0.617
2018 Chan P, Patel P, Hellmuth J, Colby DJ, Kroon E, Sacdalan C, Pinyakorn S, Jagodzinski L, Krebs S, Ananworanich J, Valcour V, Spudich S. Distribution of HIV RNA in CSF and Blood is linked to CD4/CD8 Ratio During Acute HIV. The Journal of Infectious Diseases. PMID 29741638 DOI: 10.1093/Infdis/Jiy260  0.674
2018 Sanford R, Ances BM, Meyerhoff DJ, Price RW, Fuchs D, Zetterberg H, Spudich S, Collins DL. Longitudinal Trajectories of Brain Volume and Cortical Thickness in Treated and Untreated Primary HIV Infection. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 29697762 DOI: 10.1093/Cid/Ciy362  0.688
2018 Chan P, Hellmuth J, Colby D, Kroon E, Sacdalan C, Fletcher J, Patel P, Pinyakorn S, Valcour V, Ananworanich J, Spudich S. Safety of lumbar puncture procedure in an international research setting during acute HIV infection. Journal of Virus Eradication. 4: 16-20. PMID 29568548 DOI: 10.1016/S2055-6640(20)30236-3  0.583
2018 Hsu DC, Sunyakumthorn P, Wegner M, Schuetz A, Silsorn D, Estes JD, Deleage C, Tomusange K, Lakhashe SK, Ruprecht RM, Lombardini E, Im-Erbsin R, Kuncharin Y, Phuang-Ngern Y, Inthawong D, ... ... Spudich S, et al. Central Nervous System Inflammation and Infection During Early, Non-Accelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques. Journal of Virology. PMID 29563297 DOI: 10.1128/Jvi.00222-18  0.628
2018 Burbelo PD, Price RW, Hagberg L, Hatano H, Spudich S, Deeks SG, Gisslén M. Anti-Human Immunodeficiency Virus Antibodies in the Cerebrospinal Fluid: Evidence of Early Treatment Impact on Central Nervous System Reservoir? The Journal of Infectious Diseases. PMID 29401308 DOI: 10.1093/Infdis/Jix662  0.585
2017 Crowell TA, Colby DJ, Pinyakorn S, Fletcher JLK, Kroon E, Schuetz A, Krebs SJ, Slike BM, Leyre L, Chomont N, Jagodzinski LL, Sereti I, Utay NS, Dewar R, Rerknimitr R, ... ... Spudich S, et al. Acute Retroviral Syndrome is Associated with High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 29228130 DOI: 10.1093/Cid/Cix1063  0.494
2017 Farhadian S, Patel P, Spudich S. Neurological Complications of HIV Infection. Current Infectious Disease Reports. 19: 50. PMID 29164407 DOI: 10.1007/S11908-017-0606-5  0.685
2017 Spudich SS, Ances BM. CROI 2017: Neurologic Complications of HIV Infection. Topics in Antiviral Medicine. 25: 69-76. PMID 28598791  0.659
2017 Yilmaz A, Blennow K, Hagberg L, Nilsson S, Price RW, Schouten J, Spudich S, Underwood J, Zetterberg H, Gisslén M. Neurofilament light chain protein as a marker of neuronal injury: review of its use in HIV-1 infection and reference values for HIV-negative controls. Expert Review of Molecular Diagnostics. PMID 28598205 DOI: 10.1080/14737159.2017.1341313  0.635
2017 Hellmuth J, Colby D, Valcour V, Suttichom D, Spudich S, Ananworanich J, Prueksakaew P, Sailasuta N, Allen I, Jagodzinski LL, Slike B, Ochi D, Paul R. Depression and Anxiety are Common in Acute HIV Infection and Associate with Plasma Immune Activation. Aids and Behavior. PMID 28484888 DOI: 10.1007/S10461-017-1788-4  0.55
2017 Weikum D, Shrestha R, Ferro EG, Vagenas P, Copenhaver M, Spudich S, Alpert MD, Cabello R, Lama JR, Sanchez J, Altice FL. An explanatory factor analysis of a brief self-report scale to detect neurocognitive impairment among HIV-positive men who have sex with men and transgender women in Peru. Aids Care. 1-5. PMID 28449599 DOI: 10.1080/09540121.2017.1322681  0.537
2017 Rahimy E, Li FY, Hagberg L, Fuchs D, Robertson K, Meyerhoff DJ, Zetterberg H, Price RW, Gisslén M, Spudich S. Blood-Brain Barrier Disruption Is Initiated During Primary HIV Infection and Not Rapidly Altered by Antiretroviral Therapy. The Journal of Infectious Diseases. PMID 28368497 DOI: 10.1093/Infdis/Jix013  0.672
2017 Kessing CF, Spudich S, Valcour V, Cartwright P, Chalermchai T, Fletcher JL, Nichols C, Josey BJ, Slike B, Krebs SJ, Sailsuta N, Lerdlum S, Jagodzinski L, Tipsuk S, Suttichom D, et al. High Number of Activated CD8+ T Cells Targeting HIV Antigens are Present in Cerebrospinal Fluid in Acute HIV Infection. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 28177966 DOI: 10.1097/Qai.0000000000001301  0.63
2016 Kamtchum-Tatuene J, Wan Sulaiman WA, Lekoubou A, Hellmuth J, Valcour V, Spudich S. Neurologic signs and symptoms frequently manifest in acute HIV infection. Neurology. 87: 2386. PMID 27895248 DOI: 10.1212/01.Wnl.0000510791.18526.Fb  0.603
2016 Peluso MJ, Valcour V, Phanuphak N, Ananworanich J, Fletcsher JL, Chalermchai T, Krebs SJ, Robb ML, Hellmuth J, Gisslén M, Zetterberg H, Spudich S. Immediate initiation of cART is associated with lower levels of cerebrospinal fluid YKL-40, a marker of microglial activation, in HIV-1 infection. Aids (London, England). PMID 27819802 DOI: 10.1097/Qad.0000000000001314  0.758
2016 Joseph J, Cinque P, Colosi D, Dravid A, Ene L, Fox H, Gabuzda D, Gisslen M, Beth Joseph S, Letendre S, Mukerji SS, Nath A, Perez-Valero I, Persaud D, Price RW, ... ... Spudich S, et al. Highlights of the Global HIV-1 CSF Escape Consortium Meeting, 9 June 2016, Bethesda, MD, USA. Journal of Virus Eradication. 2: 243-250. PMID 27781109  0.583
2016 Le LT, Spudich SS. HIV-Associated Neurologic Disorders and Central Nervous System Opportunistic Infections in HIV. Seminars in Neurology. 36: 373-81. PMID 27643907 DOI: 10.1055/s-0036-1585454  0.631
2016 Spudich SS, Ances BM. CROI 2016: Neurologic Complications of HIV Infection. Topics in Antiviral Medicine. 24: 29-37. PMID 27398860  0.666
2016 Gisslén M, Price RW, Andreasson U, Norgren N, Nilsson S, Hagberg L, Fuchs D, Spudich S, Blennow K, Zetterberg H. Corrigendum to: "Plasma concentration of the neurofilament light protein (NFL) is a biomarker of CNS injury in HIV infection: A cross-sectional study" [EBioMedicine 3 (216) 135-140]. Ebiomedicine. 7: 287-288. PMID 27322482 DOI: 10.1016/J.Ebiom.2016.04.021  0.58
2016 Hellmuth J, Fletcher JL, Valcour V, Kroon E, Ananworanich J, Intasan J, Lerdlum S, Narvid J, Pothisri M, Allen I, Krebs SJ, Slike B, Prueksakaew P, Jagodzinski LL, Puttamaswin S, ... ... Spudich S, et al. Neurologic signs and symptoms frequently manifest in acute HIV infection. Neurology. PMID 27287217 DOI: 10.1212/Wnl.0000000000002837  0.662
2016 Chan P, Hellmuth J, Spudich S, Valcour V. Cognitive Impairment and Persistent CNS Injury in Treated HIV. Current Hiv/Aids Reports. PMID 27188299 DOI: 10.1007/S11904-016-0319-7  0.615
2016 Wright PW, Pyakurel A, Vaida FF, Price RW, Lee E, Peterson J, Fuchs D, Zetterberg H, Robertson KR, Walter R, Meyerhoff DJ, Spudich SS, Ances BM. Putamen volume and its clinical and neurological correlates in primary HIV infection. Aids (London, England). PMID 27045376 DOI: 10.1097/Qad.0000000000001103  0.623
2016 Ganesh A, Lemongello D, Lee E, Peterson J, McLaughlin B, Ferre AL, Gillespie G, Fuchs D, Deeks SG, Hunt PW, Price RW, Spudich S, Shacklett BL. Immune Activation and HIV-Specific CD8+ T-cells in Cerebrospinal Fluid of HIV Controllers and Non-Controllers. Aids Research and Human Retroviruses. PMID 27019338 DOI: 10.1089/Aid.2015.0313  0.559
2016 Ananworanich J, Sacdalan CP, Pinyakorn S, Chomont N, de Souza M, Luekasemsuk T, Schuetz A, Krebs SJ, Dewar R, Jagodzinski L, Ubolyam S, Trichavaroj R, Tovanabutra S, Spudich S, Valcour V, et al. Virological and immunological characteristics of HIV-infected individuals at the earliest stage of infection. Journal of Virus Eradication. 2: 43-48. PMID 26889497 DOI: 10.1016/S2055-6640(20)30688-9  0.515
2016 Gisslén M, Price RW, Andreasson U, Norgren N, Nilsson S, Hagberg L, Fuchs D, Spudich S, Blennow K, Zetterberg H. Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection: A Cross-Sectional Study. Ebiomedicine. 3: 135-40. PMID 26870824 DOI: 10.1016/J.Ebiom.2015.11.036  0.628
2016 Spudich SS. Immune activation in the central nervous system throughout the course of HIV infection. Current Opinion in Hiv and Aids. 11: 226-33. PMID 26760827 DOI: 10.1097/COH.0000000000000243  0.546
2016 Chen LH, Peterson J, Robertson K, Fuchs D, Price R, Spudich S. Past Substance Use Affects Central Nervous System (CNS) Inflammation in Human Immunodeficiency Virus Infection Open Forum Infectious Diseases. 3. DOI: 10.1093/Ofid/Ofw194.60  0.4
2016 Kroon E, Ananworanich J, Le L, Intasan J, Benjapornpong K, Pinyakorn S, Karnsomlap P, Tipsuk S, Rattanamanee S, Hellmuth J, Eamyoung P, Eubanks K, Yang H, Phanuphak N, Souza M, ... ... Spudich S, et al. 50LB Central nervous system impact of vorinostat, hydroxychloroquine and maraviroc combination therapy followed by treatment interruption in individuals treated during acute HIV infection Journal of Virus Eradication. 2: 27. DOI: 10.1016/S2055-6640(20)30995-X  0.639
2015 Gega A, Kozal MJ, Chiarella J, Lee E, Peterson J, Hecht FM, Liegler T, St John EP, Simen BB, Price RW, Spudich SS. Deep sequencing of HIV-1 variants from paired plasma and cerebrospinal fluid during primary HIV infection. Journal of Virus Eradication. 1: 264-268. PMID 26855971  0.611
2015 Valcour VG, Spudich SS, Sailasuta N, Phanuphak N, Lerdlum S, Fletcher JL, Kroon ED, Jagodzinski LL, Allen IE, Adams CL, Prueksakaew P, Slike BM, Hellmuth JM, Kim JH, Ananworanich J, et al. Neurological Response to cART vs. cART plus Integrase Inhibitor and CCR5 Antagonist Initiated during Acute HIV. Plos One. 10: e0142600. PMID 26555069 DOI: 10.1371/journal.pone.0142600  0.551
2015 Kore I, Ananworanich J, Valcour V, Fletcher JL, Chalermchai T, Paul R, Reynolds J, Tipsuk S, Ubolyam S, Rattanamanee S, Jagodzinski L, Kim J, Spudich S. Neuropsychological Impairment in Acute HIV and the Effect of Immediate Antiretroviral Therapy. Journal of Acquired Immune Deficiency Syndromes (1999). 70: 393-9. PMID 26509933 DOI: 10.1097/Qai.0000000000000746  0.549
2015 Hellmuth J, Valcour V, Spudich S. CNS reservoirs for HIV: implications for eradication. Journal of Virus Eradication. 1: 67-71. PMID 26430703 DOI: 10.1016/S2055-6640(20)30489-1  0.655
2015 Arrildt KT, LaBranche CC, Joseph SB, Dukhovlinova EN, Graham WD, Ping LH, Schnell G, Sturdevant CB, Kincer LP, Mallewa M, Heyderman RS, Van Rie A, Cohen MS, Spudich S, Price RW, et al. Phenotypic Correlates of HIV-1 Macrophage Tropism. Journal of Virology. PMID 26339058 DOI: 10.1128/Jvi.00946-15  0.473
2015 Peluso MJ, Valcour V, Ananworanich J, Sithinamsuwan P, Chalermchai T, Fletcher JL, Lerdlum S, Chomchey N, Slike B, Sailasuta N, Gisslén M, Zetterberg H, Spudich S. Absence of Cerebrospinal Fluid Signs of Neuronal Injury Before and After Immediate Antiretroviral Therapy in Acute HIV Infection. The Journal of Infectious Diseases. PMID 25995196 DOI: 10.1093/Infdis/Jiv296  0.71
2015 Spudich SS, Ances BM. CROI 2015: Neurologic Complications of HIV Infection. Topics in Antiviral Medicine. 23: 47-55. PMID 25965311  0.645
2015 Ho EL, Spudich SS. Neurosyphilis and the impact of HIV infection. Sexual Health. PMID 25890619 DOI: 10.1071/SH14195  0.546
2015 Sturdevant CB, Joseph SB, Schnell G, Price RW, Swanstrom R, Spudich S. Compartmentalized replication of R5 T cell-tropic HIV-1 in the central nervous system early in the course of infection. Plos Pathogens. 11: e1004720. PMID 25811757 DOI: 10.1371/Journal.Ppat.1004720  0.64
2015 Zayyad Z, Spudich S. Neuropathogenesis of HIV: from initial neuroinvasion to HIV-associated neurocognitive disorder (HAND). Current Hiv/Aids Reports. 12: 16-24. PMID 25604237 DOI: 10.1007/S11904-014-0255-3  0.706
2015 Wright PW, Vaida FF, Fernández RJ, Rutlin J, Price RW, Lee E, Peterson J, Fuchs D, Shimony JS, Robertson KR, Walter R, Meyerhoff DJ, Spudich S, Ances BM. Cerebral white matter integrity during primary HIV infection. Aids (London, England). 29: 433-42. PMID 25513818 DOI: 10.1097/Qad.0000000000000560  0.607
2015 Ho EL, Spudich SS. Neurosyphilis and the impact of HIV infection Sexual Health. 12: 148-154. DOI: 10.1071/SH14195  0.623
2014 Peterson J, Gisslen M, Zetterberg H, Fuchs D, Shacklett BL, Hagberg L, Yiannoutsos CT, Spudich SS, Price RW. Cerebrospinal fluid (CSF) neuronal biomarkers across the spectrum of HIV infection: hierarchy of injury and detection. Plos One. 9: e116081. PMID 25541953 DOI: 10.1371/Journal.Pone.0116081  0.543
2014 Suh J, Sinclair E, Peterson J, Lee E, Kyriakides TC, Li FY, Hagberg L, Fuchs D, Price RW, Gisslen M, Spudich S. Progressive increase in central nervous system immune activation in untreated primary HIV-1 infection. Journal of Neuroinflammation. 11: 199. PMID 25465205 DOI: 10.1186/S12974-014-0199-Y  0.671
2014 Young AC, Yiannoutsos CT, Hegde M, Lee E, Peterson J, Walter R, Price RW, Meyerhoff DJ, Spudich S. Cerebral metabolite changes prior to and after antiretroviral therapy in primary HIV infection. Neurology. 83: 1592-600. PMID 25261502 DOI: 10.1212/Wnl.0000000000000932  0.628
2014 Peluso MJ, Spudich S. Treatment of HIV in the CNS: effects of antiretroviral therapy and the promise of non-antiretroviral therapeutics. Current Hiv/Aids Reports. 11: 353-62. PMID 25063356 DOI: 10.1007/S11904-014-0223-Y  0.778
2014 Spudich SS. CROI 2014: Neurologic complications of HIV infection. Topics in Antiviral Medicine. 22: 594-601. PMID 24901885  0.664
2014 Wang SX, Ho EL, Grill M, Lee E, Peterson J, Robertson K, Fuchs D, Sinclair E, Price RW, Spudich S. Peripheral neuropathy in primary HIV infection associates with systemic and central nervous system immune activation. Journal of Acquired Immune Deficiency Syndromes (1999). 66: 303-10. PMID 24732871 DOI: 10.1097/Qai.0000000000000167  0.669
2014 Price RW, Spudich SS, Peterson J, Joseph S, Fuchs D, Zetterberg H, Gisslén M, Swanstrom R. Evolving character of chronic central nervous system HIV infection. Seminars in Neurology. 34: 7-13. PMID 24715483 DOI: 10.1055/S-0034-1372337  0.597
2014 Spudich S, Meyer AC. HIV Neurology. Preface. Seminars in Neurology. 34: 5-6. PMID 24715482 DOI: 10.1055/S-0034-1372336  0.669
2014 Gold JA, Grill M, Peterson J, Pilcher C, Lee E, Hecht FM, Fuchs D, Yiannoutsos CT, Price RW, Robertson K, Spudich S. Longitudinal characterization of depression and mood states beginning in primary HIV infection. Aids and Behavior. 18: 1124-32. PMID 24385231 DOI: 10.1007/S10461-013-0688-5  0.563
2014 Dahl V, Gisslen M, Hagberg L, Peterson J, Shao W, Spudich S, Price RW, Palmer S. An example of genetically distinct HIV type 1 variants in cerebrospinal fluid and plasma during suppressive therapy. The Journal of Infectious Diseases. 209: 1618-22. PMID 24338353 DOI: 10.1093/Infdis/Jit805  0.509
2013 Spudich SS, Ances BM. Neurologic complications of HIV infection: highlights from the 2013 Conference on Retroviruses and Opportunistic Infections. Topics in Antiviral Medicine. 21: 100-8. PMID 23981597  0.654
2013 Price RW, Peterson J, Fuchs D, Angel TE, Zetterberg H, Hagberg L, Spudich S, Smith RD, Jacobs JM, Brown JN, Gisslen M. Approach to cerebrospinal fluid (CSF) biomarker discovery and evaluation in HIV infection. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 1147-58. PMID 23943280 DOI: 10.1007/S11481-013-9491-3  0.426
2013 Spudich S. HIV and neurocognitive dysfunction. Current Hiv/Aids Reports. 10: 235-43. PMID 23860944 DOI: 10.1007/S11904-013-0171-Y  0.676
2013 Ho EL, Ronquillo R, Altmeppen H, Spudich SS, Price RW, Sinclair E. Cellular Composition of Cerebrospinal Fluid in HIV-1 Infected and Uninfected Subjects. Plos One. 8: e66188. PMID 23822975 DOI: 10.1371/journal.pone.0066188  0.573
2013 Yilmaz A, Yiannoutsos CT, Fuchs D, Price RW, Crozier K, Hagberg L, Spudich S, Gisslén M. Cerebrospinal fluid neopterin decay characteristics after initiation of antiretroviral therapy. Journal of Neuroinflammation. 10: 62. PMID 23664008 DOI: 10.1186/1742-2094-10-62  0.65
2013 Peluso MJ, Meyerhoff DJ, Price RW, Peterson J, Lee E, Young AC, Walter R, Fuchs D, Brew BJ, Cinque P, Robertson K, Hagberg L, Zetterberg H, Gisslén M, Spudich S. Cerebrospinal fluid and neuroimaging biomarker abnormalities suggest early neurological injury in a subset of individuals during primary HIV infection. The Journal of Infectious Diseases. 207: 1703-12. PMID 23460748 DOI: 10.1093/Infdis/Jit088  0.75
2013 Dahl V, Peterson J, Spudich S, Lee E, Shacklett BL, Price RW, Palmer S. Single-copy assay quantification of HIV-1 RNA in paired cerebrospinal fluid and plasma samples from elite controllers. Aids (London, England). 27: 1145-9. PMID 23211774 DOI: 10.1097/Qad.0B013E32835Cf235  0.634
2012 Sailasuta N, Ross W, Ananworanich J, Chalermchai T, DeGruttola V, Lerdlum S, Pothisri M, Busovaca E, Ratto-Kim S, Jagodzinski L, Spudich S, Michael N, Kim JH, Valcour V. Change in brain magnetic resonance spectroscopy after treatment during acute HIV infection. Plos One. 7: e49272. PMID 23229129 DOI: 10.1371/Journal.Pone.0049272  0.652
2012 Spudich SS, Ances BM. Neurologic complications of HIV infection. Topics in Antiviral Medicine. 20: 41-7. PMID 22710906  0.67
2012 Spudich S, González-Scarano F. HIV-1-related central nervous system disease: current issues in pathogenesis, diagnosis, and treatment. Cold Spring Harbor Perspectives in Medicine. 2: a007120. PMID 22675662 DOI: 10.1101/Cshperspect.A007120  0.703
2012 Peluso MJ, Ferretti F, Peterson J, Lee E, Fuchs D, Boschini A, Gisslén M, Angoff N, Price RW, Cinque P, Spudich S. Cerebrospinal fluid HIV escape associated with progressive neurologic dysfunction in patients on antiretroviral therapy with well controlled plasma viral load. Aids (London, England). 26: 1765-74. PMID 22614889 DOI: 10.1097/Qad.0B013E328355E6B2  0.73
2012 Valcour V, Chalermchai T, Sailasuta N, Marovich M, Lerdlum S, Suttichom D, Suwanwela NC, Jagodzinski L, Michael N, Spudich S, van Griensven F, de Souza M, Kim J, Ananworanich J. Central nervous system viral invasion and inflammation during acute HIV infection. The Journal of Infectious Diseases. 206: 275-82. PMID 22551810 DOI: 10.1093/Infdis/Jis326  0.653
2012 Angel TE, Jacobs JM, Spudich SS, Gritsenko MA, Fuchs D, Liegler T, Zetterberg H, Camp DG, Price RW, Smith RD. The cerebrospinal fluid proteome in HIV infection: change associated with disease severity. Clinical Proteomics. 9: 3. PMID 22433316 DOI: 10.1186/1559-0275-9-3  0.561
2012 Gold J, Peterson J, Lee E, Fuchs D, Price R, Yiannoutsos C, Robertson K, Spudich S. Depression and Mood States and Correlations with Biomarkers of Central Nervous System Disease in Primary-HIV Infection (P01.262) Neurology. 78: P01.262-P01.262. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P01.262  0.544
2011 Dahl V, Lee E, Peterson J, Spudich SS, Leppla I, Sinclair E, Fuchs D, Palmer S, Price RW. Raltegravir treatment intensification does not alter cerebrospinal fluid HIV-1 infection or immunoactivation in subjects on suppressive therapy. The Journal of Infectious Diseases. 204: 1936-45. PMID 22021620 DOI: 10.1093/infdis/jir667  0.579
2011 Schnell G, Joseph S, Spudich S, Price RW, Swanstrom R. HIV-1 replication in the central nervous system occurs in two distinct cell types. Plos Pathogens. 7: e1002286. PMID 22007152 DOI: 10.1371/Journal.Ppat.1002286  0.647
2011 Spudich SS, Ances BM. Central nervous system complications of HIV infection Topics in Antiviral Medicine. 19: 48-57. PMID 21868822  0.565
2011 Spudich S, Gisslen M, Hagberg L, Lee E, Liegler T, Brew B, Fuchs D, Tambussi G, Cinque P, Hecht FM, Price RW. Central nervous system immune activation characterizes primary human immunodeficiency virus 1 infection even in participants with minimal cerebrospinal fluid viral burden. The Journal of Infectious Diseases. 204: 753-60. PMID 21844301 DOI: 10.1093/Infdis/Jir387  0.657
2011 Ho EL, Spudich SS, Lee E, Fuchs D, Sinclair E, Price RW. Minocycline fails to modulate cerebrospinal fluid HIV infection or immune activation in chronic untreated HIV-1 infection: results of a pilot study. Aids Research and Therapy. 8: 17. PMID 21569420 DOI: 10.1186/1742-6405-8-17  0.584
2011 Edén A, Fuchs D, Hagberg L, Nilsson S, Spudich S, Svennerholm B, Price RW, Gisslén M. Reply to Seligman Journal of Infectious Diseases. 204: 174-175. DOI: 10.1093/Infdis/Jir235  0.544
2010 Edén A, Fuchs D, Hagberg L, Nilsson S, Spudich S, Svennerholm B, Price RW, Gisslén M. HIV-1 viral escape in cerebrospinal fluid of subjects on suppressive antiretroviral treatment Journal of Infectious Diseases. 202: 1819-1825. PMID 21050119 DOI: 10.1086/657342  0.617
2010 Hagberg L, Cinque P, Gisslen M, Brew BJ, Spudich S, Bestetti A, Price RW, Fuchs D. Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection. Aids Research and Therapy. 7: 15. PMID 20525234 DOI: 10.1186/1742-6405-7-15  0.713
2010 Probasco JC, Deeks SG, Lee E, Hoh R, Hunt PW, Liegler T, Price RW, Spudich SS. Cerebrospinal fluid in HIV-1 systemic viral controllers: Absence of HIV-1 RNA and intrathecal inflammation Aids. 24: 1001-1005. PMID 20299968 DOI: 10.1097/QAD.0b013e328331e15b  0.616
2010 Schnell G, Price RW, Swanstrom R, Spudich S. Compartmentalization and clonal amplification of HIV-1 variants in the cerebrospinal fluid during primary infection. Journal of Virology. 84: 2395-407. PMID 20015984 DOI: 10.1128/Jvi.01863-09  0.694
2010 Schnell G, Joseph S, Spudich S, Price R, Swanstrom R. Where are macrophage-tropic viruses? Journal of the International Aids Society. 13: O3. DOI: 10.1186/1758-2652-13-S3-O3  0.527
2010 Hagberg L, Cinque P, Gisslen M, Brew BJ, Spudich S, Bestetti A, Price RW, Fuchs D. Cerebrospinal fluid neopterin: An informative biomarker of central nervous system immune activation in HIV-1 infection Aids Research and Therapy. 7. DOI: 10.1186/1742-6405-7-15  0.547
2009 Gisslén M, Krut J, Andreasson U, Blennow K, Cinque P, Brew BJ, Spudich S, Hagberg L, Rosengren L, Price RW, Zetterberg H. Amyloid and tau cerebrospinal fluid biomarkers in HIV infection Bmc Neurology. 9. PMID 20028512 DOI: 10.1186/1471-2377-9-63  0.645
2009 Yilmaz A, Gisslén M, Spudich S, Lee E, Jayewardene A, Aweeka F, Price RW. Raltegravir cerebrospinal fluid concentrations in HIV-1 infection Plos One. 4. PMID 19721718 DOI: 10.1371/Journal.Pone.0006877  0.648
2009 Schnell G, Spudich S, Harrington P, Price RW, Swanstrom R. Compartmentalized human immunodeficiency virus type 1 originates from long-lived cells in some subjects with HIV-1-associated dementia. Plos Pathogens. 5: e1000395. PMID 19390619 DOI: 10.1371/Journal.Ppat.1000395  0.616
2009 Brew BJ, Gisslen M, Pemberton L, Cinque P, Hagberg L, Price RW, Blennow K, Spudich S. 110. CSF t-tau, p-tau and Amyloid Beta 1-42 in HIV Infection Journal of Clinical Neuroscience. 16: 464. DOI: 10.1016/J.Jocn.2008.07.009  0.507
2008 Price RW, Parham R, Kroll JL, Wring SA, Baker B, Sailstad J, Hoh R, Liegler T, Spudich S, Kuritzkes DR, Deeks SG. Enfuvirtide cerebrospinal fluid (CSF) pharmacokinetics and potential use in defining CSF HIV-1 origin Antiviral Therapy. 13: 369-374. PMID 18572749  0.562
2008 Price RW, Spudich S. Antiretroviral therapy and central nervous system HIV type 1 infection Journal of Infectious Diseases. 197: S294-S306. PMID 18447615 DOI: 10.1086/533419  0.685
2008 Sinclair E, Ronquillo R, Lollo N, Deeks SG, Hunt P, Yiannoutsos CT, Spudich S, Price RW. Antiretroviral treatment effect on immune activation reduces cerebrospinal fluid HIV-1 infection. Journal of Acquired Immune Deficiency Syndromes (1999). 47: 544-52. PMID 18362693 DOI: 10.1097/Qai.0B013E318162754F  0.638
2008 Yilmaz A, Price RW, Spudich S, Fuchs D, Hagberg L, Gisslén M. Persistent intrathecal immune activation in HIV-1-infected individuals on antiretroviral therapy Journal of Acquired Immune Deficiency Syndromes. 47: 168-173. PMID 17971711 DOI: 10.1097/Qai.0B013E31815Ace97  0.67
2007 Edén A, Price RW, Spudich S, Fuchs D, Hagberg L, Gisslén M. Immune activation of the central nervous system is still present after >4 years of effective highly active antiretroviral therapy Journal of Infectious Diseases. 196: 1779-1783. PMID 18190258 DOI: 10.1086/523648  0.596
2007 Gisslen M, Hagberg L, Rosengren L, Brew BJ, Cinque P, Spudich S, Price RW. Defining and evaluating HIV-related neurodegenerative disease and its treatment targets: A combinatorial approach to use of cerebrospinal fluid molecular biomarkers Journal of Neuroimmune Pharmacology. 2: 112-119. PMID 18040834 DOI: 10.1007/S11481-006-9035-1  0.65
2006 Spudich S, Lollo N, Liegler T, Deeks SG, Price RW. Treatment benefit on cerebrospinal fluid HIV-1 levels in the setting of systemic virological suppression and failure Journal of Infectious Diseases. 194: 1686-1696. PMID 17109340 DOI: 10.1086/508750  0.63
2006 Hunt PW, Harrigan PR, Huang W, Bates M, Williamson DW, McCune JW, Price RW, Spudich SS, Lampiris H, Hoh R, Leigler T, Martin JN, Deeks SG. Prevalence of CXCR4 tropism among antiretroviral-treated HIV-1-infected patients with detectable viremia Journal of Infectious Diseases. 194: 926-930. PMID 16960780 DOI: 10.1086/507312  0.496
2005 Spudich SS, Nilsson AC, Lollo ND, Liegler TJ, Petropoulos CJ, Deeks SG, Paxinos EE, Price RW. Cerebrospinal fluid HIV infection and pleocytosis: relation to systemic infection and antiretroviral treatment. Bmc Infectious Diseases. 5: 98. PMID 16266436 DOI: 10.1186/1471-2334-5-98  0.615
2005 Spudich SS, Huang W, Nilsson AC, Petropoulos CJ, Liegler TJ, Whitcomb JM, Price RW. HIV-1 chemokine coreceptor utilization in paired cerebrospinal fluid and plasma samples: a survey of subjects with viremia. The Journal of Infectious Diseases. 191: 890-8. PMID 15717264 DOI: 10.1086/428095  0.546
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