Roger J. Ward, Ed.D. - Publications

Affiliations: 
2009 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Higher Education, Administration Education, Mental Health

0/247 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
Low-probability matches (unlikely to be authored by this person)
2024 Hallinan CM, Ward R, Hart GK, Sullivan C, Pratt N, Ng AP, Capurro D, Van Der Vegt A, Liaw ST, Daly O, Luxan BG, Bunker D, Boyle D. Seamless EMR data access: Integrated governance, digital health and the OMOP-CDM. Bmj Health & Care Informatics. 31. PMID 38387992 DOI: 10.1136/bmjhci-2023-100953  0.01
2023 Owens JA, Lilly FRW, Allen A, Falcon M, Ward RJ. From to : The Critical Role of Medical Housing for Individuals Seeking Abortion Care. American Journal of Public Health. 113: 1241-1243. PMID 37939341 DOI: 10.2105/AJPH.2023.307464  0.01
2023 El-Hayek C, Barzegar S, Faux N, Doyle K, Pillai P, Mutch SJ, Vaisey A, Ward R, Sanci L, Dunn AG, Hellard ME, Hocking JS, Verspoor K, Boyle DI. An evaluation of existing text de-identification tools for use with patient progress notes from Australian general practice. International Journal of Medical Informatics. 173: 105021. PMID 36870249 DOI: 10.1016/j.ijmedinf.2023.105021  0.01
2021 Carli S, Salgado JCS, Meleiro LP, Ward RJ. Covalent Immobilization of Chondrostereum purpureum Endopolygalacturonase on Ferromagnetic Nanoparticles: Catalytic Properties and Biotechnological Application. Applied Biochemistry and Biotechnology. PMID 34553326 DOI: 10.1007/s12010-021-03688-5  0.01
2021 Furtado GP, Carli S, Meleiro LP, Salgado JCS, Ward RJ. Enhanced hydrolytic efficiency of an engineered CBM11-glucanase enzyme chimera against barley β-d-glucan extracts. Food Chemistry. 365: 130460. PMID 34237573 DOI: 10.1016/j.foodchem.2021.130460  0.01
2021 Liu Y, Shao YT, Ward R, Ma L, Gui HX, Hao Q, Mu X, Yang Y, An S, Guo XX, Xu TR. The C-terminal of the α1b-adreneroceptor is a key determinant for its structure integrity and biological functions. Bioscience, Biotechnology, and Biochemistry. PMID 33693487 DOI: 10.1093/bbb/zbab034  0.01
2021 Pinheiro MP, Reis RAG, Dupree P, Ward RJ. Plant cell wall architecture guided design of CBM3-GH11 chimeras with enhanced xylanase activity using a tandem repeat left-handed β-3-prism scaffold. Computational and Structural Biotechnology Journal. 19: 1108-1118. PMID 33680354 DOI: 10.1016/j.csbj.2021.01.011  0.01
2020 Ward RJ, Pediani JD, Marsango S, Jolly R, Stoneman MR, Biener G, Handel TM, Raicu V, Milligan G. Chemokine receptor CXCR4 oligomerization is disrupted selectively by the antagonist ligand IT1t. The Journal of Biological Chemistry. PMID 33268380 DOI: 10.1074/jbc.RA120.016612  0.01
2020 Hao P, Yu J, Ward R, Liu Y, Hao Q, An S, Xu T. Eukaryotic translation initiation factors as promising targets in cancer therapy. Cell Communication and Signaling : Ccs. 18: 175. PMID 33148274 DOI: 10.1186/s12964-020-00607-9  0.01
2020 Monteiro LMO, Vici AC, Pinheiro MP, Heinen PR, de Oliveira AHC, Ward RJ, Prade RA, Buckeridge MS, Polizeli MLTM. A Highly Glucose Tolerant ß-Glucosidase from Malbranchea pulchella (MpBg3) Enables Cellulose Saccharification. Scientific Reports. 10: 6998. PMID 32332833 DOI: 10.1038/S41598-020-63972-Y  0.01
2020 Pasin TM, Salgado JCS, Scarcella ASA, de Oliveira TB, de Lucas RC, Cereia M, Rosa JC, Ward RJ, Buckeridge MS, Polizeli MLTM. A Halotolerant Endo-1,4-β-Xylanase from Aspergillus clavatus with Potential Application for Agroindustrial Residues Saccharification. Applied Biochemistry and Biotechnology. PMID 31960367 DOI: 10.1007/s12010-020-03232-x  0.01
2020 Mendonça EHM, Avanci NC, Romano LH, Branco DL, de Pádua AX, Ward RJ, Baptista Neto Ád, Lourenzoni MR. Recombinant xylanase production by Escherichia coli using a non-induced expression system with different nutrient sources Brazilian Journal of Chemical Engineering. 37: 29-39. DOI: 10.1007/s43153-019-00004-x  0.01
2019 Silva JCR, Salgado JCS, Vici AC, Ward RJ, Polizeli MLTM, Guimarães LHS, Furriel RPM, Jorge JA. A novel Trichoderma reesei mutant RP698 with enhanced cellulase production. Brazilian Journal of Microbiology : [Publication of the Brazilian Society For Microbiology]. PMID 31667801 DOI: 10.1007/s42770-019-00167-2  0.01
2019 Carli S, Meleiro LP, Ward RJ. Biochemical and kinetic characterization of the recombinant GH28 Stereum purpureum endopolygalacturonase and its biotechnological application. International Journal of Biological Macromolecules. 137: 469-474. PMID 31242449 DOI: 10.1016/j.ijbiomac.2019.06.165  0.01
2019 Stoneman MR, Biener G, Ward RJ, Pediani JD, Badu D, Eis A, Popa I, Milligan G, Raicu V. A general method to quantify ligand-driven oligomerization from fluorescence-based images. Nature Methods. PMID 31110281 DOI: 10.1038/S41592-019-0408-9  0.01
2019 Carli S, Carneiro LABC, Ward RJ, Meleiro LP. Immobilization of a β-glucosidase and an endoglucanase in ferromagnetic nanoparticles: A study of synergistic effects. Protein Expression and Purification. 160: 28-35. PMID 30940468 DOI: 10.1016/j.pep.2019.03.016  0.01
2019 Müskens FM, Ward RJ, Herkt D, van de Langemheen H, Tobin AB, Liskamp RMJ, Milligan G. Design, Synthesis, and Evaluation of a Diazirine Photoaffinity Probe for Ligand-Based Receptor Capture Targeting G Protein-Coupled Receptors. Molecular Pharmacology. 95: 196-209. PMID 30514721 DOI: 10.1124/Mol.118.114249  0.01
2018 Milligan G, Ward RJ, Marsango S. GPCR homo-oligomerization. Current Opinion in Cell Biology. 57: 40-47. PMID 30453145 DOI: 10.1016/j.ceb.2018.10.007  0.01
2018 Furtado GP, Lourenzoni MR, Fuzo CA, Fonseca-Maldonado R, Guazzaroni ME, Ribeiro LF, Ward RJ. Engineering the affinity of a family 11 carbohydrate binding module to improve binding of branched over unbranched polysaccharides. International Journal of Biological Macromolecules. PMID 30195003 DOI: 10.1016/j.ijbiomac.2018.09.022  0.01
2018 Ribeiro LF, Ribeiro LFC, Barreto MQ, Ward RJ. Protein Engineering Strategies to Expand CRISPR-Cas9 Applications. International Journal of Genomics. 2018: 1652567. PMID 30155473 DOI: 10.1155/2018/1652567  0.01
2018 Salgado JCS, Meleiro LP, Carli S, Ward RJ. Glucose tolerant and glucose stimulated β-glucosidases - A review. Bioresource Technology. PMID 30093225 DOI: 10.1016/j.biortech.2018.07.137  0.01
2018 Carneiro LABC, Yu L, Dupree P, Ward RJ. Characterization of a β-galactosidase from Bacillus subtilis with transgalactosylation activity. International Journal of Biological Macromolecules. PMID 30036621 DOI: 10.1016/J.Ijbiomac.2018.07.116  0.01
2018 Liu Y, Zeng H, Pediani JD, Ward RJ, Chen LY, Wu N, Ma L, Tang M, Yang Y, An S, Guo XX, Hao Q, Xu TR. Visualization of the activation of the histamine H3 receptor (H3R) using novel Fluorescence Resonance Energy Transfer Biosensors and their potential application to the study of H3R pharmacology. The Febs Journal. PMID 29701013 DOI: 10.1111/febs.14484  0.01
2018 Liu Y, Chen LY, Zeng H, Ward R, Wu N, Ma L, Mu X, Li QL, Yang Y, An S, Guo XX, Hao Q, Xu TR. Assessing the real-time activation of the cannabinoid CB1 receptor and the associated structural changes using a FRET biosensor. The International Journal of Biochemistry & Cell Biology. PMID 29626639 DOI: 10.1016/j.biocel.2018.04.003  0.01
2017 Heinen PR, Bauermeister A, Ribeiro LF, Messias JM, Almeida PZ, Moraes LAB, Vargas-Rechia CG, de Oliveira AHC, Ward RJ, Filho EXF, Kadowaki MK, Jorge JA, Polizeli MLTM. GH11 xylanase from Aspergillus tamarii Kita: Purification by one-step chromatography and xylooligosaccharides hydrolysis monitored in real-time by mass spectrometry. International Journal of Biological Macromolecules. 108: 291-299. PMID 29191425 DOI: 10.1016/j.ijbiomac.2017.11.150  0.01
2017 Fonseca-Maldonado R, Meleiro LP, Mendes LFS, Alves LF, Carli S, Morero LD, Basso LGM, Costa-Filho AJ, Ward RJ. Lignocellulose binding of a Cel5A-RtCBM11 chimera with enhanced β-glucanase activity monitored by electron paramagnetic resonance. Biotechnology For Biofuels. 10: 269. PMID 29163671 DOI: 10.1186/s13068-017-0964-0  0.01
2017 Carneiro LABC, Ward RJ. Functionalization of paramagnetic nanoparticles for protein immobilization and purification. Analytical Biochemistry. 45-51. PMID 29154787 DOI: 10.1016/j.ab.2017.11.005  0.01
2017 Meleiro LP, Carli S, Fonseca-Maldonado R, da Silva Torricillas M, Zimbardi ALRL, Ward RJ, Jorge JA, Furriel RPM. Overexpression of a Cellobiose-Glucose-Halotolerant Endoglucanase from Scytalidium thermophilum. Applied Biochemistry and Biotechnology. 185: 316-333. PMID 29150773 DOI: 10.1007/s12010-017-2660-8  0.01
2017 Marsango S, Ward RJ, Alvarez-Curto E, Milligan G. Muscarinic receptor oligomerization. Neuropharmacology. PMID 29146505 DOI: 10.1016/j.neuropharm.2017.11.023  0.01
2017 Meleiro LP, Salgado JCS, Maldonado RF, Carli S, Moraes LAB, Ward RJ, Jorge JA, Furriel RPM. Engineering the GH1 β-glucosidase from Humicola insolens: Insights on the stimulation of activity by glucose and xylose. Plos One. 12: e0188254. PMID 29145480 DOI: 10.1371/journal.pone.0188254  0.01
2017 Pediani JD, Ward RJ, Marsango S, Milligan G. Spatial Intensity Distribution Analysis: Studies of G Protein-Coupled Receptor Oligomerisation. Trends in Pharmacological Sciences. 39: 175-186. PMID 29032835 DOI: 10.1016/j.tips.2017.09.001  0.01
2017 Marsango S, Caltabiano G, Jiménez-Rosés M, Millan MJ, Pediani JD, Ward RJ, Milligan G. A Molecular Basis for Selective Antagonist Destabilization of Dopamine D Receptor Quaternary Organization. Scientific Reports. 7: 2134. PMID 28522847 DOI: 10.1038/s41598-017-02249-3  0.01
2017 Ward RJ, Pediani JD, Harikumar KG, Miller LJ, Milligan G. Spatial Intensity Distribution Analysis Quantifies the Extent and Regulation of Homo-Dimerization of the Secretin Receptor. The Biochemical Journal. PMID 28424368 DOI: 10.1042/BCJ20170184  0.01
2017 Zambelli VO, Chioato L, Gutierrez VP, Ward RJ, Cury Y. Structural determinants of the hyperalgesic activity of myotoxic Lys49-phospholipase A2. The Journal of Venomous Animals and Toxins Including Tropical Diseases. 23: 7. PMID 28203248 DOI: 10.1186/s40409-017-0099-6  0.01
2017 Bergamachi Silva SR, Pinheiro MP, Fuzo CA, Silva SR, Ferreira TL, Lourenzoni MR, Nonato MC, Vieira DS, Ward RJ. The Role of Local Residue Environmental Changes in Thermostable Mutants of the GH11 Xylanase from Bacillus subtilis. International Journal of Biological Macromolecules. PMID 28109807 DOI: 10.1016/j.ijbiomac.2017.01.054  0.01
2017 Guo H, An S, Ward RJ, Yang Y, Liu Y, Guo XX, Hao Q, Xu TR. Methods used to study the oligomeric structure of G protein-coupled receptors. Bioscience Reports. PMID 28062602 DOI: 10.1042/BSR20160547  0.01
2017 Riess J, Floch N, Martin M, Orme J, Staniszewska A, Menard L, Cuomo ME, O'Neill D, Ward R, Finlay R, McKerrecher D, Cheng M, Vang D, Tsai R, Ye C, et al. Antitumor activity of osimertinib in NSCLC harboring EGFR exon 20 insertions. Journal of Clinical Oncology. 35: 9030-9030. DOI: 10.1200/JCO.2017.35.15_SUPPL.9030  0.01
2016 Antony B, Driban JB, Price LL, Lo GH, Ward RJ, Nevitt M, Lynch J, Eaton CB, Ding C, McAlindon TE. The relationship between meniscal pathology and osteoarthritis depends on the type of meniscal damage visible on magnetic resonance images: data from the Osteoarthritis Initiative. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. PMID 27539889 DOI: 10.1016/J.Joca.2016.08.004  0.01
2016 Driban JB, Stout AC, Duryea J, Lo GH, Harvey WF, Price LL, Ward RJ, Eaton CB, Barbe MF, Lu B, McAlindon TE. Coronal tibial slope is associated with accelerated knee osteoarthritis: data from the Osteoarthritis Initiative. Bmc Musculoskeletal Disorders. 17: 299. PMID 27432004 DOI: 10.1186/S12891-016-1158-9  0.01
2016 Ribeiro LF, Tullman J, Nicholes N, Silva SR, Vieira DS, Ostermeier M, Ward RJ. A xylose-stimulated xylanase-xylose binding protein chimera created by random nonhomologous recombination. Biotechnology For Biofuels. 9: 119. PMID 27274356 DOI: 10.1186/S13068-016-0529-7  0.01
2016 Pediani JD, Ward RJ, Godin AG, Marsango S, Milligan G. Dynamic Regulation of Quaternary Organization of the M1 Muscarinic Receptor by Subtype-Selective Antagonist Drugs. The Journal of Biological Chemistry. PMID 27080256 DOI: 10.1074/jbc.M115.712562  0.01
2016 Liu Y, An S, Ward R, Yang Y, Guo XX, Li W, Xu TR. G protein-coupled receptors as promising cancer targets. Cancer Letters. PMID 27000991 DOI: 10.1016/J.Canlet.2016.03.031  0.01
2016 Alponti JS, Fonseca Maldonado R, Ward RJ. Thermostabilization of Bacillus subtilis GH11 xylanase by surface charge engineering. International Journal of Biological Macromolecules. 87: 522-8. PMID 26955749 DOI: 10.1016/j.ijbiomac.2016.03.003  0.01
2016 Roberts CC, Kransdorf MJ, Beaman FD, Adler RS, Amini B, Appel M, Bernard SA, Fries IB, Germano IM, Greenspan BS, Holly LT, Kubicky CD, Shek-Man Lo S, Mosher TJ, Sloan AE, ... ... Ward RJ, et al. ACR Appropriateness Criteria Follow-Up of Malignant or Aggressive Musculoskeletal Tumors. Journal of the American College of Radiology : Jacr. PMID 26922595 DOI: 10.1016/j.jacr.2015.12.019  0.01
2016 Duarte A, Cotter SC, Reavey CE, Ward RJ, De Gasperin O, Kilner RM. Social immunity of the family: parental contributions to a public good modulated by brood size. Evolutionary Ecology. 30: 123-135. PMID 26900202 DOI: 10.1007/s10682-015-9806-3  0.01
2016 de Lima EA, Machado CB, Zanphorlin LM, Ward RJ, Sato HH, Ruller R. GH53 Endo-Beta-1,4-Galactanase from a Newly Isolated Bacillus licheniformis CBMAI 1609 as an Enzymatic Cocktail Supplement for Biomass Saccharification. Applied Biochemistry and Biotechnology. 179: 415-26. PMID 26879978 DOI: 10.1007/s12010-016-2003-1  0.01
2016 de Lima EA, Machado CB, Zanphorlin LM, Ward RJ, Sato HH, Ruller R. GH53 Endo-Beta-1,4-Galactanase from a Newly Isolated Bacillus licheniformis CBMAI 1609 as an Enzymatic Cocktail Supplement for Biomass Saccharification Applied Biochemistry and Biotechnology. 1-12. DOI: 10.1007/s12010-016-2003-1  0.01
2015 Decker SJ, Grajo JR, Hazelton TR, Hoang KN, McDonald JS, Otero HJ, Patel MJ, Prober AS, Retrouvey M, Rosenkrantz AB, Roth CG, Ward RJ. Research Challenges and Opportunities for Clinically Oriented Academic Radiology Departments. Academic Radiology. PMID 26598485 DOI: 10.1016/J.Acra.2015.10.007  0.01
2015 Tuite MJ, Kransdorf MJ, Beaman FD, Adler RS, Amini B, Appel M, Bernard SA, Dempsey ME, Fries IB, Greenspan BS, Khurana B, Mosher TJ, Walker EA, Ward RJ, Wessell DE, et al. ACR Appropriateness Criteria Acute Trauma to the Knee. Journal of the American College of Radiology : Jacr. 12: 1164-72. PMID 26541130 DOI: 10.1016/j.jacr.2015.08.014  0.01
2015 An S, Yang Y, Ward R, Liu Y, Guo XX, Xu TR. A-Raf: A new star of the family of raf kinases. Critical Reviews in Biochemistry and Molecular Biology. 1-12. PMID 26508523 DOI: 10.3109/10409238.2015.1102858  0.01
2015 Vici AC, da Cruz AF, Facchini FD, de Carvalho CC, Pereira MG, Fonseca-Maldonado R, Ward RJ, Pessela BC, Fernandez-Lorente G, Torres FA, Jorge JA, Polizeli ML. Beauveria bassiana Lipase A expressed in Komagataella (Pichia) pastoris with potential for biodiesel catalysis. Frontiers in Microbiology. 6: 1083. PMID 26500628 DOI: 10.3389/fmicb.2015.01083  0.01
2015 Ribeiro LF, Nicholes N, Tullman J, Ribeiro LF, Fuzo CA, Vieira DS, Furtado GP, Ostermeier M, Ward RJ. Insertion of a xylanase in xylose binding protein results in a xylose-stimulated xylanase. Biotechnology For Biofuels. 8: 118. PMID 26279676 DOI: 10.1186/S13068-015-0293-0  0.01
2015 Heldt G, Ward R. Evaluation of Ultrasound-Based Sensor to Monitor Respiratory and Non-Respiratory Movement and Timing in Infants. Ieee Transactions On Bio-Medical Engineering. PMID 26276983 DOI: 10.1109/TBME.2015.2466633  0.01
2015 Driban JB, Ward RJ, Eaton CB, Lo GH, Price LL, Lu B, McAlindon TE. Meniscal extrusion or subchondral damage characterize incident accelerated osteoarthritis: Data from the osteoarthritis initiative. Clinical Anatomy (New York, N.Y.). 28: 792-9. PMID 26149125 DOI: 10.1002/Ca.22590  0.01
2015 Ward RJ, Dexter DT, Crichton RR. Ageing, neuroinflammation and neurodegeneration. Frontiers in Bioscience (Scholar Edition). 7: 189-204. PMID 25961695 DOI: 10.2741/S433  0.01
2015 Bancroft LW, Kransdorf MJ, Adler R, Appel M, Beaman FD, Bernard SA, Bruno MA, Dempsey ME, Fries IB, Khoury V, Khurana B, Mosher TJ, Roberts CC, Tuite MJ, Ward RJ, et al. ACR Appropriateness Criteria Acute Trauma to the Foot. Journal of the American College of Radiology : Jacr. 12: 575-81. PMID 25935824 DOI: 10.1016/j.jacr.2015.02.018  0.01
2015 Ward RJ, Pediani JD, Godin AG, Milligan G. Regulation of oligomeric organization of the serotonin 5-hydroxytryptamine 2C (5-HT2C) receptor observed by spatial intensity distribution analysis. The Journal of Biological Chemistry. 290: 12844-57. PMID 25825490 DOI: 10.1074/jbc.M115.644724  0.01
2015 Machado CB, Citadini AP, Goldbeck R, de Lima EA, Figueiredo FL, da Silva TM, Hoffmam ZB, de Sousa AS, Squina FM, de Lourdes Teixeira de Moraes Polizeli M, Ruller R, Ward RJ. Increased biomass saccharification by supplementation of a commercial enzyme cocktail with endo-arabinanase from Bacillus licheniformis. Biotechnology Letters. 37: 1455-62. PMID 25801671 DOI: 10.1007/s10529-015-1818-0  0.01
2015 Liste MJ, Caltabiano G, Ward RJ, Alvarez-Curto E, Marsango S, Milligan G. The molecular basis of oligomeric organization of the human M3 muscarinic acetylcholine receptor. Molecular Pharmacology. 87: 936-53. PMID 25769304 DOI: 10.1124/mol.114.096925  0.01
2015 Mosher TJ, Kransdorf MJ, Adler R, Appel M, Beaman FD, Bernard SA, Bruno MA, Dempsey ME, Fries IB, Khoury V, Khurana B, Roberts CC, Tuite MJ, Ward RJ, Zoga AC, et al. ACR Appropriateness Criteria acute trauma to the ankle. Journal of the American College of Radiology : Jacr. 12: 221-7. PMID 25743919 DOI: 10.1016/j.jacr.2014.11.015  0.01
2015 Ward RJ, Dexter DT, Crichton RR. Neurodegenerative diseases and therapeutic strategies using iron chelators. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). 31: 267-73. PMID 25716300 DOI: 10.1016/J.Jtemb.2014.12.012  0.01
2015 Furtado GP, Santos CR, Cordeiro RL, Ribeiro LF, de Moraes LA, Damásio AR, Polizeli Mde L, Lourenzoni MR, Murakami MT, Ward RJ. Enhanced xyloglucan-specific endo-β-1,4-glucanase efficiency in an engineered CBM44-XegA chimera. Applied Microbiology and Biotechnology. 99: 5095-107. PMID 25605422 DOI: 10.1007/s00253-014-6324-0  0.01
2015 An S, Yang Y, Ward R, Liu Y, Guo XX, Xu TR. Raf-interactome in tuning the complexity and diversity of Raf function. The Febs Journal. 282: 32-53. PMID 25333451 DOI: 10.1111/febs.13113  0.01
2015 Guazzaroni ME, Silva-Rocha R, Ward RJ. Synthetic biology approaches to improve biocatalyst identification in metagenomic library screening. Microbial Biotechnology. 8: 52-64. PMID 25123225 DOI: 10.1111/1751-7915.12146  0.01
2015 Liu Y, Yang Y, Ward R, An S, Guo XX, Li W, Xu TR. Biased signalling: The instinctive skill of the cell in the selection of appropriate signalling pathways Biochemical Journal. 470: 155-167. DOI: 10.1042/BJ20150358  0.01
2015 Meleiro LP, Salgado JCS, Maldonado RF, Alponti JS, Zimbardi ALRL, Jorge JA, Ward RJ, Furriel RPM. A Neurospora crassa ß-glucosidase with potential for lignocellulose hydrolysis shows strong glucose tolerance and stimulation by glucose and xylose Journal of Molecular Catalysis B: Enzymatic. 122: 131-140. DOI: 10.1016/j.molcatb.2015.09.003  0.01
2014 Ribeiro LF, De Lucas RC, Vitcosque GL, Ribeiro LF, Ward RJ, Rubio MV, Damásio AR, Squina FM, Gregory RC, Walton PH, Jorge JA, Prade RA, Buckeridge MS, Polizeli Mde L. A novel thermostable xylanase GH10 from Malbranchea pulchella expressed in Aspergillus nidulans with potential applications in biotechnology. Biotechnology For Biofuels. 7: 115. PMID 25788980 DOI: 10.1186/1754-6834-7-115  0.01
2014 Ward RJ, Zucca FA, Duyn JH, Crichton RR, Zecca L. The role of iron in brain ageing and neurodegenerative disorders. The Lancet. Neurology. 13: 1045-60. PMID 25231526 DOI: 10.1016/S1474-4422(14)70117-6  0.01
2014 Bago R, Malik N, Munson MJ, Prescott AR, Davies P, Sommer E, Shpiro N, Ward R, Cross D, Ganley IG, Alessi DR. Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase. The Biochemical Journal. 463: 413-27. PMID 25177796 DOI: 10.1042/Bj20140889  0.01
2014 Zhang M, Driban JB, Price LL, Harper D, Lo GH, Miller E, Ward RJ, McAlindon TE. Development of a rapid knee cartilage damage quantification method using magnetic resonance images. Bmc Musculoskeletal Disorders. 15: 264. PMID 25098589 DOI: 10.1186/1471-2474-15-264  0.01
2014 Ruller R, Alponti J, Deliberto LA, Zanphorlin LM, Machado CB, Ward RJ. Concommitant adaptation of a GH11 xylanase by directed evolution to create an alkali-tolerant/thermophilic enzyme. Protein Engineering, Design & Selection : Peds. 27: 255-62. PMID 25096197 DOI: 10.1093/protein/gzu027  0.01
2014 de Giuseppe PO, Souza Tde A, Souza FH, Zanphorlin LM, Machado CB, Ward RJ, Jorge JA, Furriel Rdos P, Murakami MT. Structural basis for glucose tolerance in GH1 β-glucosidases. Acta Crystallographica. Section D, Biological Crystallography. 70: 1631-9. PMID 24914974 DOI: 10.1107/S1399004714006920  0.01
2014 Driban JB, Eaton CB, Lo GH, Ward RJ, Lu B, McAlindon TE. Association of knee injuries with accelerated knee osteoarthritis progression: data from the Osteoarthritis Initiative. Arthritis Care & Research. 66: 1673-9. PMID 24782446 DOI: 10.1002/Acr.22359  0.01
2014 Fonseca-Maldonado R, Maller A, Bonneil E, Thibault P, Botelho-Machado C, Ward RJ, Polizeli Mde L. Biochemical properties of glycosylation and characterization of a histidine acid phosphatase (phytase) expressed in Pichia pastoris. Protein Expression and Purification. 99: 43-9. PMID 24680732 DOI: 10.1016/J.Pep.2014.03.006  0.01
2014 Zakrys L, Ward RJ, Pediani JD, Godin AG, Graham GJ, Milligan G. Roundabout 1 exists predominantly as a basal dimeric complex and this is unaffected by binding of the ligand Slit2. The Biochemical Journal. 461: 61-73. PMID 24673457 DOI: 10.1042/BJ20140190  0.01
2014 Ward RJ, Lallemand F, de Witte P. Influence of adolescent heavy session drinking on the systemic and brain innate immune system. Alcohol and Alcoholism (Oxford, Oxfordshire). 49: 193-7. PMID 24532587 DOI: 10.1093/alcalc/agu002  0.01
2014 Ward RJ, Weissman BN, Kransdorf MJ, Adler R, Appel M, Bancroft LW, Bernard SA, Bruno MA, Fries IB, Morrison WB, Mosher TJ, Roberts CC, Scharf SC, Tuite MJ, Zoga AC. ACR appropriateness criteria acute hip pain-suspected fracture. Journal of the American College of Radiology : Jacr. 11: 114-20. PMID 24368044 DOI: 10.1016/j.jacr.2013.10.023  0.01
2014 Ward RJ, Milligan G. Structural and biophysical characterisation of G protein-coupled receptor ligand binding using resonance energy transfer and fluorescent labelling techniques. Biochimica Et Biophysica Acta. 1838: 3-14. PMID 23590995 DOI: 10.1016/j.bbamem.2013.04.007  0.01
2014 Anderton M, Ward R, Galer A, Cross D, Marks L, Finlay R. Influence of early discovery safety on eliminating off-target insulin receptor activity and selection of the candidate drug AZD9291 Toxicology Letters. 229: S53. DOI: 10.1016/J.TOXLET.2014.06.221  0.01
2014 Fonseca-Maldonado R, Ribeiro LF, Furtado GP, Arruda LM, Meleiro LP, Alponti JS, Botelho-Machado C, Vieira DS, Bonneil E, Furriel RDPM, Thibault P, Ward RJ. Synergistic action of co-expressed xylanase/laccase mixtures against milled sugar cane bagasse Process Biochemistry. 49: 1152-1161. DOI: 10.1016/J.Procbio.2014.03.027  0.01
2014 Souza FHM, Meleiro LP, Machado CB, Zimbardi ALRL, Maldonado RF, Souza TACB, Masui DC, Murakami MT, Jorge JA, Ward RJ, Furriel RPM. Gene cloning, expression and biochemical characterization of a glucose- and xylose-stimulated β-glucosidase from Humicola insolens RP86 Journal of Molecular Catalysis B: Enzymatic. 106: 1-10. DOI: 10.1016/J.MOLCATB.2014.04.007  0.01
2013 Driban JB, Lo GH, Price L, Pang J, Miller E, Ward RJ, Hunter DJ, Eaton CB, Lynch JA, McAlindon TE. Bone marrow lesion volume reduction is not associated with improvement of other periarticular bone measures: data from the Osteoarthritis Initiative. Arthritis Research & Therapy. 15: R153. PMID 24432365 DOI: 10.1186/Ar4336  0.01
2013 Ribeiro LF, Bressan F, Furtado GP, Meireles F, Ward RJ. D-xylose detection in Escherichia coli by a xylose binding protein-dependent response. Journal of Biotechnology. 168: 440-5. PMID 24161920 DOI: 10.1016/j.jbiotec.2013.10.019  0.01
2013 Yang Y, Li H, Ward R, Gao L, Wei JF, Xu TR. Novel oxytocin receptor agonists and antagonists: a patent review (2002 - 2013). Expert Opinion On Therapeutic Patents. 24: 29-46. PMID 24094047 DOI: 10.1517/13543776.2014.845168  0.01
2013 Driban JB, Price L, Lo GH, Pang J, Hunter DJ, Miller E, Ward RJ, Eaton CB, Lynch JA, McAlindon TE. Evaluation of bone marrow lesion volume as a knee osteoarthritis biomarker--longitudinal relationships with pain and structural changes: data from the Osteoarthritis Initiative. Arthritis Research & Therapy. 15: R112. PMID 24020939 DOI: 10.1186/Ar4292  0.01
2013 Xu TR, Yang Y, Ward R, Gao L, Liu Y. Orexin receptors: multi-functional therapeutic targets for sleeping disorders, eating disorders, drug addiction, cancers and other physiological disorders. Cellular Signalling. 25: 2413-23. PMID 23917208 DOI: 10.1016/j.cellsig.2013.07.025  0.01
2013 Fonseca-Maldonado R, Vieira DS, Alponti JS, Bonneil E, Thibault P, Ward RJ. Engineering the pattern of protein glycosylation modulates the thermostability of a GH11 xylanase. The Journal of Biological Chemistry. 288: 25522-34. PMID 23846692 DOI: 10.1074/Jbc.M113.485953  0.01
2013 Hudson BD, Due-Hansen ME, Christiansen E, Hansen AM, Mackenzie AE, Murdoch H, Pandey SK, Ward RJ, Marquez R, Tikhonova IG, Ulven T, Milligan G. Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor. The Journal of Biological Chemistry. 288: 17296-312. PMID 23589301 DOI: 10.1074/Jbc.M113.455337  0.01
2013 Ward RJ, Xu TR, Milligan G. GPCR oligomerization and receptor trafficking. Methods in Enzymology. 521: 69-90. PMID 23351734 DOI: 10.1016/B978-0-12-391862-8.00004-1  0.01
2013 Pang J, Driban JB, Destenaves G, Miller E, Lo GH, Ward RJ, Price LL, Lynch JA, Eaton CB, Eckstein F, McAlindon TE. Quantification of bone marrow lesion volume and volume change using semi-automated segmentation: data from the osteoarthritis initiative. Bmc Musculoskeletal Disorders. 14: 3. PMID 23281825 DOI: 10.1186/1471-2474-14-3  0.01
2013 Furtado GP, Ribeiro LF, Lourenzoni MR, Ward RJ. A designed bifunctional laccase/β-1,3-1,4-glucanase enzyme shows synergistic sugar release from milled sugarcane bagasse. Protein Engineering, Design & Selection : Peds. 26: 15-23. PMID 23012443 DOI: 10.1093/protein/gzs057  0.01
2013 Souza FHM, Inocentes RF, Ward RJ, Jorge JA, Furriel RPM. Glucose and xylose stimulation of a β-glucosidase from the thermophilic fungus Humicola insolens: A kinetic and biophysical study Journal of Molecular Catalysis B: Enzymatic. 94: 119-128. DOI: 10.1016/J.MOLCATB.2013.05.012  0.01
2012 Laarman AJ, Mijnheer G, Mootz JM, van Rooijen WJ, Ruyken M, Malone CL, Heezius EC, Ward R, Milligan G, van Strijp JA, de Haas CJ, Horswill AR, van Kessel KP, Rooijakkers SH. Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis. The Embo Journal. 31: 3607-19. PMID 22850671 DOI: 10.1038/Emboj.2012.212  0.01
2012 Chudinova TV, Belekhova MG, Tostivint H, Ward R, Rio JP, Kenigfest NB. Differences in parvalbumin and calbindin chemospecificity in the centers of the turtle ascending auditory pathway revealed by double immunofluorescence labeling. Brain Research. 1473: 87-103. PMID 22820305 DOI: 10.1016/j.brainres.2012.07.022  0.01
2012 Fonseca-Maldonado R, Ferreira TL, Ward RJ. The bactericidal effect of human secreted group IID phospholipase A2 results from both hydrolytic and non-hydrolytic activities. Biochimie. 94: 1437-40. PMID 22490726 DOI: 10.1016/j.biochi.2012.03.020  0.01
2012 Ward RJ, Dexter DT, Crichton RR. Chelating agents for neurodegenerative diseases. Current Medicinal Chemistry. 19: 2760-72. PMID 22489724  0.01
2012 Xu TR, Ward RJ, Pediani JD, Milligan G. Intramolecular fluorescence resonance energy transfer (FRET) sensors of the orexin OX1 and OX2 receptors identify slow kinetics of agonist activation. The Journal of Biological Chemistry. 287: 14937-49. PMID 22389503 DOI: 10.1074/jbc.M111.334300  0.01
2012 Otero HJ, Fang CH, Sekar M, Ward RJ, Neumann PJ. Accuracy, risk and the intrinsic value of diagnostic imaging: a review of the cost-utility literature. Academic Radiology. 19: 599-606. PMID 22342653 DOI: 10.1016/j.acra.2012.01.011  0.01
2012 Tuite MJ, Daffner RH, Weissman BN, Bancroft L, Bennett DL, Blebea JS, Bruno MA, Fries IB, Hayes CW, Kransdorf MJ, Luchs JS, Morrison WB, Roberts CC, Scharf SC, Stoller DW, ... ... Ward RJ, et al. ACR appropriateness criteria(®) acute trauma to the knee. Journal of the American College of Radiology : Jacr. 9: 96-103. PMID 22305695 DOI: 10.1016/j.jacr.2011.10.013  0.01
2012 Aragão EA, Vieira DS, Chioato L, Ferreira TL, Lourenzoni MR, Silva SR, Ward RJ. Characterization of suramin binding sites on the human group IIA secreted phospholipase A2 by site-directed mutagenesis and molecular dynamics simulation. Archives of Biochemistry and Biophysics. 519: 17-22. PMID 22248627 DOI: 10.1016/j.abb.2012.01.002  0.01
2012 Damásio AR, Ribeiro LF, Ribeiro LF, Furtado GP, Segato F, Almeida FB, Crivellari AC, Buckeridge MS, Souza TA, Murakami MT, Ward RJ, Prade RA, Polizeli ML. Functional characterization and oligomerization of a recombinant xyloglucan-specific endo-β-1,4-glucanase (GH12) from Aspergillus niveus. Biochimica Et Biophysica Acta. 1824: 461-7. PMID 22230786 DOI: 10.1016/J.Bbapap.2011.12.005  0.01
2012 Chioato L, Aragão EA, Ferreira TL, Ward RJ. Active site mutants of human secreted Group IIA Phospholipase A2 lacking hydrolytic activity retain their bactericidal effect. Biochimie. 94: 132-6. PMID 21986368 DOI: 10.1016/j.biochi.2011.09.027  0.01
2012 Santos CR, Paiva JH, Sforça ML, Neves JL, Navarro RZ, Cota J, Akao PK, Hoffmam ZB, Meza AN, Smetana JH, Nogueira ML, Polikarpov I, Xavier-Neto J, Squina FM, Ward RJ, et al. Dissecting structure-function-stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168. The Biochemical Journal. 441: 95-104. PMID 21880019 DOI: 10.1042/BJ20110869  0.01
2012 Vieira DS, Ward RJ. Conformation analysis of a surface loop that controls active site access in the GH11 xylanase A from Bacillus subtilis. Journal of Molecular Modeling. 18: 1473-9. PMID 21785938 DOI: 10.1007/s00894-011-1172-7  0.01
2012 Souza T, Trindade D, Tonoli C, Santos C, Ward R, Oliveira A, Murakami M. Structural characterization of trypanosomatids kinases: targets to drug discovery Acta Crystallographica Section a Foundations of Crystallography. 68: s157-s157. DOI: 10.1107/S0108767312096985  0.01
2011 Ribeiro LF, Furtado GP, Lourenzoni MR, Costa-Filho AJ, Santos CR, Nogueira SC, Betini JA, Polizeli Mde L, Murakami MT, Ward RJ. Engineering bifunctional laccase-xylanase chimeras for improved catalytic performance. The Journal of Biological Chemistry. 286: 43026-38. PMID 22006920 DOI: 10.1074/jbc.M111.253419  0.01
2011 Driban JB, Lo GH, Lee JY, Ward RJ, Miller E, Pang J, Price LL, McAlindon TE. Quantitative bone marrow lesion size in osteoarthritic knees correlates with cartilage damage and predicts longitudinal cartilage loss. Bmc Musculoskeletal Disorders. 12: 217. PMID 21961433 DOI: 10.1186/1471-2474-12-217  0.01
2011 Ward RJ, Pediani JD, Milligan G. Heteromultimerization of cannabinoid CB(1) receptor and orexin OX(1) receptor generates a unique complex in which both protomers are regulated by orexin A. The Journal of Biological Chemistry. 286: 37414-28. PMID 21908614 DOI: 10.1074/jbc.M111.287649  0.01
2011 Xu TR, Ward RJ, Pediani JD, Milligan G. The orexin OX(1) receptor exists predominantly as a homodimer in the basal state: potential regulation of receptor organization by both agonist and antagonist ligands. The Biochemical Journal. 439: 171-83. PMID 21770891 DOI: 10.1042/BJ20110230  0.01
2011 Ward RJ, Alvarez-Curto E, Milligan G. Using the Flp-Inâ„¢ T-Rexâ„¢ system to regulate GPCR expression. Methods in Molecular Biology (Clifton, N.J.). 746: 21-37. PMID 21607850 DOI: 10.1007/978-1-61779-126-0_2  0.01
2011 Souza TA, Trindade DM, Tonoli CC, Santos CR, Ward RJ, Arni RK, Oliveira AH, Murakami MT. Molecular adaptability of nucleoside diphosphate kinase b from trypanosomatid parasites: stability, oligomerization and structural determinants of nucleotide binding. Molecular Biosystems. 7: 2189-95. PMID 21528129 DOI: 10.1039/c0mb00307g  0.01
2011 Smith NJ, Ward RJ, Stoddart LA, Hudson BD, Kostenis E, Ulven T, Morris JC, Tränkle C, Tikhonova IG, Adams DR, Milligan G. Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator. Molecular Pharmacology. 80: 163-73. PMID 21498659 DOI: 10.1124/Mol.110.070789  0.01
2011 Lallemand F, Ward RJ, De Witte P, Verbanck P. Binge drinking +/- chronic nicotine administration alters extracellular glutamate and arginine levels in the nucleus accumbens of adult male and female Wistar rats. Alcohol and Alcoholism (Oxford, Oxfordshire). 46: 373-82. PMID 21478495 DOI: 10.1093/alcalc/agr031  0.01
2011 Minty JJ, Lesnefsky AA, Lin F, Chen Y, Zaroff TA, Veloso AB, Xie B, McConnell CA, Ward RJ, Schwartz DR, Rouillard JM, Gao Y, Gulari E, Lin XN. Evolution combined with genomic study elucidates genetic bases of isobutanol tolerance in Escherichia coli. Microbial Cell Factories. 10: 18. PMID 21435272 DOI: 10.1186/1475-2859-10-18  0.01
2011 Ruller R, Silva-Rocha R, Silva A, Cruz Schneider MP, Ward RJ. A practical teaching course in directed protein evolution using the green fluorescent protein as a model. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. 39: 21-7. PMID 21433249 DOI: 10.1002/bmb.20430  0.01
2011 Ward RJ, Lallemand F, de Witte P, Crichton RR, Piette J, Tipton K, Hemmings K, Pitard A, Page M, Della Corte L, Taylor D, Dexter D. Anti-inflammatory actions of a taurine analogue, ethane β-sultam, in phagocytic cells, in vivo and in vitro. Biochemical Pharmacology. 81: 743-51. PMID 21232527 DOI: 10.1016/J.Bcp.2010.12.030  0.01
2011 Schmidt J, Smith NJ, Christiansen E, Tikhonova IG, Grundmann M, Hudson BD, Ward RJ, Drewke C, Milligan G, Kostenis E, Ulven T. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3. The Journal of Biological Chemistry. 286: 10628-40. PMID 21220428 DOI: 10.1074/Jbc.M110.210872  0.01
2011 Ward RJ, Pediani JD, Milligan G. Ligand-induced internalization of the orexin OX(1) and cannabinoid CB(1) receptors assessed via N-terminal SNAP and CLIP-tagging. British Journal of Pharmacology. 162: 1439-52. PMID 21175569 DOI: 10.1111/j.1476-5381.2010.01156.x  0.01
2011 Dexter DT, Statton SA, Whitmore C, Freinbichler W, Weinberger P, Tipton KF, Della Corte L, Ward RJ, Crichton RR. Clinically available iron chelators induce neuroprotection in the 6-OHDA model of Parkinson's disease after peripheral administration. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 223-31. PMID 21165659 DOI: 10.1007/s00702-010-0531-3  0.01
2011 Ward RJ, Crichton RR, Taylor DL, Della Corte L, Srai SK, Dexter DT. Iron and the immune system. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 315-28. PMID 20878427 DOI: 10.1007/s00702-010-0479-3  0.01
2011 Crichton RR, Dexter DT, Ward RJ. Brain iron metabolism and its perturbation in neurological diseases. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 301-14. PMID 20809066 DOI: 10.1007/s00702-010-0470-z  0.01
2011 Bräuer SL, Cadillo-Quiroz H, Ward RJ, Yavitt JB, Zinder SH. Methanoregula boonei gen. nov., sp. nov., an acidiphilic methanogen isolated from an acidic peat bog. International Journal of Systematic and Evolutionary Microbiology. 61: 45-52. PMID 20154331 DOI: 10.1099/Ijs.0.021782-0  0.01
2011 Furtado GP, Ribeiro LF, Santos CR, Tonoli CC, de Souza AR, Oliveira RR, Murakami MT, Ward RJ. Biochemical and structural characterization of a β-1,3–1,4-glucanase from Bacillus subtilis 168 Process Biochemistry. 46: 1202-1206. DOI: 10.1016/J.PROCBIO.2011.01.037  0.01
2011 Tikhonova IG, Smith NJ, Ward RJ, Stoddart LA, Hudson BD, Kostenis E, Ulven T, Morris JC, Adams D, Milligan G. Probing Allosteric Binding Site Mapping in the Free Fatty Acid 2 receptor Biophysical Journal. 100: 52a. DOI: 10.1016/J.Bpj.2010.12.483  0.01
2011 Alvarez-Curto E, Ward RJ, Milligan G. Novel assay technologies for the discovery of G protein-coupled receptor drugs Neuromethods. 60: 231-253. DOI: 10.1007/978-1-61779-179-6_12  0.01
2010 Botelho-Machado C, Cabral FJ, Soares CS, Moreira EB, Morais ER, Magalhães LG, Gomes MS, Guerra-Sá R, Rosa JC, Ruller R, Ward RJ, Rodrigues V. Characterization and mRNA expression analysis of PI31, an endogenous proteasome inhibitor from Schistosoma mansoni. Parasitology Research. 107: 1163-71. PMID 20680343 DOI: 10.1007/s00436-010-1984-x  0.01
2010 Alvarez-Curto E, Ward RJ, Pediani JD, Milligan G. Ligand regulation of the quaternary organization of cell surface M 3 muscarinic acetylcholine receptors analyzed by fluorescence resonance energy transfer (FRET) imaging and homogeneous time-resolved FRET Journal of Biological Chemistry. 285: 23318-23330. PMID 20489201 DOI: 10.1074/jbc.M110.122184  0.01
2010 Belekhova MG, Chudinova TV, Repérant J, Ward R, Jay B, Vesselkin NP, Kenigfest NB. Core-and-belt organisation of the mesencephalic and forebrain auditory centres in turtles: expression of calcium-binding proteins and metabolic activity. Brain Research. 1345: 84-102. PMID 20478279 DOI: 10.1016/j.brainres.2010.05.026  0.01
2010 Park D, Finlay JA, Ward RJ, Weinman CJ, Krishnan S, Paik M, Sohn KE, Callow ME, Callow JA, Handlin DL, Willis CL, Fischer DA, Angert ER, Kramer EJ, Ober CK. Antimicrobial behavior of semifluorinated-quaternized triblock copolymers against airborne and marine microorganisms. Acs Applied Materials & Interfaces. 2: 703-11. PMID 20356271 DOI: 10.1021/Am900748V  0.01
2010 Yang RK, Roth CG, Ward RJ, deJesus JO, Mitchell DG. Optimizing abdominal MR imaging: approaches to common problems. Radiographics : a Review Publication of the Radiological Society of North America, Inc. 30: 185-99. PMID 20083593 DOI: 10.1148/rg.301095076  0.01
2009 Tonoli CC, Vieira PS, Ward RJ, Arni RK, de Oliveira AH, Murakami MT. Production, purification, crystallization and preliminary X-ray diffraction studies of the nucleoside diphosphate kinase b from Leishmania major. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 1116-9. PMID 19923730 DOI: 10.1107/S1744309109037567  0.01
2009 Ward RJ, Colivicchi MA, Allen R, Schol F, Lallemand F, de Witte P, Ballini C, Corte LD, Dexter D. Neuro-inflammation induced in the hippocampus of 'binge drinking' rats may be mediated by elevated extracellular glutamate content. Journal of Neurochemistry. 111: 1119-28. PMID 19765190 DOI: 10.1111/j.1471-4159.2009.06389.x  0.01
2009 da Silva TM, Michelin M, Damásio AR, Maller A, Almeida FB, Ruller R, Ward RJ, Rosa JC, Jorge JA, Terenzi HF, Polizeli Mde L. Purification and biochemical characterization of a novel alpha-glucosidase from Aspergillus niveus. Antonie Van Leeuwenhoek. 96: 569-78. PMID 19757138 DOI: 10.1007/s10482-009-9372-1  0.01
2009 Lallemand F, Ward RJ, De Witte P. The influence of chronic nicotine administration on behavioural and neurochemical parameters in male and female rats after repeated binge drinking exposure. Alcohol and Alcoholism (Oxford, Oxfordshire). 44: 535-46. PMID 19737814 DOI: 10.1093/alcalc/agp047  0.01
2009 Aragão EA, Randazzo-Moura P, Rostelato-Ferreira S, Rodrigues-Simioni L, Ward RJ. Shared structural determinants for the calcium-independent liposome membrane permeabilization and sarcolemma depolarization in Bothropstoxin-I, a LYS49-PLA(2) from the venom of Bothrops jararacussu. The International Journal of Biochemistry & Cell Biology. 41: 2588-93. PMID 19729073 DOI: 10.1016/j.biocel.2009.08.016  0.01
2009 da Silva TM, Maller A, Damásio AR, Michelin M, Ward RJ, Hirata IY, Jorge JA, Terenzi HF, de Polizeli ML. Properties of a purified thermostable glucoamylase from Aspergillus niveus. Journal of Industrial Microbiology & Biotechnology. 36: 1439-46. PMID 19697071 DOI: 10.1007/s10295-009-0630-z  0.01
2009 de Oliveira AH, Aragão EA, Sá JM, Chioato L, Bugs-Bortoleto R, Ruller R, Ferreira TL, Ward RJ. Calcium-independent membrane damage by venom phospholipases A2. Protein and Peptide Letters. 16: 877-86. PMID 19689413  0.01
2009 Ferreira TL, Ward RJ. The interaction of bothropstoxin-I (Lys49-PLA(2)) with liposome membranes. Toxicon : Official Journal of the International Society On Toxinology. 54: 525-30. PMID 19500612 DOI: 10.1016/j.toxicon.2009.05.025  0.01
2009 Ward RJ, Lee L, Graham K, Satkunendran T, Yoshikawa K, Ling E, Harper L, Austin R, Nieuwenhuis E, Clarke ID, Hui CC, Dirks PB. Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma. Cancer Research. 69: 4682-90. PMID 19487286 DOI: 10.1158/0008-5472.Can-09-0342  0.01
2009 de Oliveira AH, Ferreira TL, Ward RJ. Reduced pH induces an inactive non-native conformation of the monomeric bothropstoxin-I (Lys49-PLA2). Toxicon : Official Journal of the International Society On Toxinology. 54: 373-8. PMID 19450617 DOI: 10.1016/j.toxicon.2009.04.022  0.01
2009 Vieira DS, Degrève L, Ward RJ. Characterization of temperature dependent and substrate-binding cleft movements in Bacillus circulans family 11 xylanase: a molecular dynamics investigation. Biochimica Et Biophysica Acta. 1790: 1301-6. PMID 19409448 DOI: 10.1016/j.bbagen.2009.04.017  0.01
2009 Fonseca RG, Ferreira TL, Ward RJ. Refolding and purification of the human secreted group IID phospholipase A2 expressed as inclusion bodies in Escherichia coli. Protein Expression and Purification. 67: 82-7. PMID 19376232 DOI: 10.1016/j.pep.2009.04.006  0.01
2009 Médina M, Repérant J, Ward R, Jay B, Miceli D, Kenigfest N. Preoptic FMRF-amide-like immunoreactive projections to the retina in the lamprey (Lampetra fluviatilis). Brain Research. 1273: 58-65. PMID 19344699 DOI: 10.1016/j.brainres.2009.03.051  0.01
2009 Repérant J, Ward R, Médina M, Kenigfest NB, Rio JP, Miceli D, Jay B. Synaptic circuitry in the retinorecipient layers of the optic tectum of the lamprey (Lampetra fluviatilis). A combined hodological, GABA and glutamate immunocytochemical study. Brain Structure & Function. 213: 395-422. PMID 19252925 DOI: 10.1007/s00429-009-0205-9  0.01
2009 Vieira DS, Aragão EA, Lourenzoni MR, Ward RJ. Mapping of suramin binding sites on the group IIA human secreted phospholipase A2. Bioorganic Chemistry. 37: 41-5. PMID 19251299 DOI: 10.1016/j.bioorg.2009.01.002  0.01
2009 Ward RJ, Clements KD, Choat JH, Angert ER. Cytology of terminally differentiated Epulopiscium mother cells. Dna and Cell Biology. 28: 57-64. PMID 19196050 DOI: 10.1089/Dna.2008.0801  0.01
2009 Aragão EA, Chioato L, Ferreira TL, de Medeiros AI, Secatto A, Faccioli LH, Ward RJ. Suramin inhibits macrophage activation by human group IIA phospholipase A2, but does not affect bactericidal activity of the enzyme. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 58: 210-7. PMID 19169647 DOI: 10.1007/s00011-008-8137-z  0.01
2009 Ward RJ, Jenkins L, Milligan G. Selectivity and functional consequences of interactions of family A G protein-coupled receptors with neurochondrin and periplakin Journal of Neurochemistry. 109: 182-192. PMID 19166508 DOI: 10.1111/j.1471-4159.2009.05918.x  0.01
2009 Ward RJ, Lallemand F, de Witte P. Biochemical and neurotransmitter changes implicated in alcohol-induced brain damage in chronic or 'binge drinking' alcohol abuse. Alcohol and Alcoholism (Oxford, Oxfordshire). 44: 128-35. PMID 19155229 DOI: 10.1093/alcalc/agn100  0.01
2009 Ward RJ, Wilmet S, Legssyer R, Leroy D, Toussaint L, Crichton RR, Pierreux C, Hue L, Piette J, Srai SK, Solanky N, Klein D, Summer K. Effects of marginal iron overload on iron homeostasis and immune function in alveolar macrophages isolated from pregnant and normal rats. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 22: 211-23. PMID 18690415 DOI: 10.1007/s10534-008-9155-6  0.01
2008 Rigos CF, Nobre TM, Zaniquelli MED, Ward RJ, Ciancaglini P. The association of Na,K-ATPase subunits studied by circular dichroism, surface tension and dilatational elasticity Journal of Colloid and Interface Science. 325: 478-484. PMID 18597766 DOI: 10.1016/j.jcis.2008.06.011  0.01
2008 Ward RJ, Lallemand F, de Witte P, Dexter DT. Neurochemical pathways involved in the protective effects of nicotine and ethanol in preventing the development of Parkinson's disease: potential targets for the development of new therapeutic agents. Progress in Neurobiology. 85: 135-47. PMID 18482793 DOI: 10.1016/j.pneurobio.2008.03.003  0.01
2008 Ward RJ, Buckland-Wright JC. Rates of medial tibiofemoral joint space narrowing in osteoarthritis studies consistent despite methodological differences. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 16: 330-6. PMID 18325452 DOI: 10.1016/j.joca.2007.06.015  0.01
2008 Ward RJ, Angert ER. DNA replication during endospore development in Metabacterium polyspora. Molecular Microbiology. 67: 1360-70. PMID 18284580 DOI: 10.1111/J.1365-2958.2008.06129.X  0.01
2008 Miceli D, Repérant J, Ward R, Rio JP, Jay B, Médina M, Kenigfest NB. Fine structure of the visual dorsolateral anterior thalamic nucleus of the pigeon (Columba livia): a hodological and GABA-immunocytochemical study. The Journal of Comparative Neurology. 507: 1351-78. PMID 18189307 DOI: 10.1002/cne.21635  0.01
2008 Aragão EA, Chioato L, Ward RJ. Permeabilization of E. coli K12 inner and outer membranes by bothropstoxin-I, A LYS49 phospholipase A2 from Bothrops jararacussu. Toxicon : Official Journal of the International Society On Toxinology. 51: 538-46. PMID 18160090 DOI: 10.1016/j.toxicon.2007.11.004  0.01
2008 Ferreira TL, Ruller R, Chioato L, Ward RJ. Insights on calcium-independent phospholipid membrane damage by Lys49-PLA2 using tryptophan scanning mutagenesis of bothropstoxin-I from Bothrops jararacussu. Biochimie. 90: 1397-406. PMID 18036350 DOI: 10.1016/j.biochi.2007.10.012  0.01
2008 Ruller R, Deliberto L, Ferreira TL, Ward RJ. Thermostable variants of the recombinant xylanase A from Bacillus subtilis produced by directed evolution show reduced heat capacity changes. Proteins. 70: 1280-93. PMID 17876824 DOI: 10.1002/prot.21617  0.01
2008 Hauk P, Negrotto S, Romero EC, Vasconcellos SA, Genovez MÉ, Ward RJ, Schattner M, Gómez RM, Ho PL. Corrigendum to “Expression and characterization of HlyX hemolysin from Leptospira interrogans serovar Copenhageni: Potentiation of hemolytic activity by LipL32” [Biochem. Biophys. Res. Commun. 333 (2005) 1341–1347] Biochemical and Biophysical Research Communications. 372: 948. DOI: 10.1016/J.BBRC.2008.05.106  0.01
2007 Smiseth PT, Ward RJ, Moore AJ. Parents influence asymmetric sibling competition: experimental evidence with partially dependent young. Ecology. 88: 3174-82. PMID 18229851 DOI: 10.1890/06-1992.1  0.01
2007 Ward RJ, Dirks PB. Cancer stem cells: at the headwaters of tumor development. Annual Review of Pathology. 2: 175-89. PMID 18039097 DOI: 10.1146/annurev.pathol.2.010506.091847  0.01
2007 Kenigfest NB, Rio JP, Belekhova MG, Repérant J, Ward R, Jay B, Vesselkin NP. Tectorotundal connections in turtles: an electron microscopic tracing and GABA-immunocytochemical study. Brain Research. 1186: 144-54. PMID 17996857 DOI: 10.1016/j.brainres.2007.09.038  0.01
2007 Michelin M, Ruller R, Ward RJ, Moraes LA, Jorge JA, Terenzi HF, Polizeli Mde L. Purification and biochemical characterization of a thermostable extracellular glucoamylase produced by the thermotolerant fungus Paecilomyces variotii. Journal of Industrial Microbiology & Biotechnology. 35: 17-25. PMID 17938981 DOI: 10.1007/s10295-007-0261-1  0.01
2007 Chioato L, Aragão EA, Lopes Ferreira T, Medeiros AI, Faccioli LH, Ward RJ. Mapping of the structural determinants of artificial and biological membrane damaging activities of a Lys49 phospholipase A2 by scanning alanine mutagenesis. Biochimica Et Biophysica Acta. 1768: 1247-57. PMID 17346668 DOI: 10.1016/J.BBAMEM.2007.01.023  0.01
2006 de Oliveira AH, Ruiz JC, Cruz AK, Greene LJ, Rosa JC, Ward RJ. Subproteomic analysis of soluble proteins of the microsomal fraction from two Leishmania species. Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics. 1: 300-8. PMID 20483262 DOI: 10.1016/j.cbd.2006.05.003  0.01
2006 Bugs MR, Bortoleto-Bugs RK, Cornélio ML, Ward RJ. An ultraviolet photoacoustic spectroscopy study of the interaction between Lys49-phospholipase A2 and amphiphilic molecules. Biochemical and Biophysical Research Communications. 353: 889-94. PMID 17210121 DOI: 10.1016/J.BBRC.2006.12.085  0.01
2006 Francke F, Ward RJ, Jenkins L, Kellett E, Richter D, Milligan G, Bächner D. Interaction of neurochondrin with the melanin-concentrating hormone receptor 1 interferes with G protein-coupled signal transduction but not agonist-mediated internalization. The Journal of Biological Chemistry. 281: 32496-507. PMID 16945926 DOI: 10.1074/Jbc.M602889200  0.01
2006 Bortoleto-Bugs RK, Bugs MR, Neto AA, Ward RJ. A micelle nucleation model for the interaction of dodecyl sulphate with Lys49-phospholipases A(2). Biophysical Chemistry. 125: 213-20. PMID 16945473 DOI: 10.1016/J.BPC.2006.08.002  0.01
2006 Costa-Neto CM, Parreiras-E-Silva LT, Ruller R, Oliveira EB, Miranda A, Oliveira L, Ward RJ. Molecular modeling of the human eukaryotic translation initiation factor 5A (eIF5A) based on spectroscopic and computational analyses. Biochemical and Biophysical Research Communications. 347: 634-40. PMID 16842744 DOI: 10.1016/J.BBRC.2006.06.119  0.01
2006 de Oliveira AH, Ruiz JC, Cruz AK, Greene LJ, Rosa JC, Ward RJ. Expression in E. coli and purification of the nucleoside diphosphate kinase b from Leishmania major. Protein Expression and Purification. 49: 244-50. PMID 16809050 DOI: 10.1016/j.pep.2006.05.010  0.01
2006 Rigos CF, de Lima Santos H, Ward RJ, Ciancaglini P. Lipid bilayer stabilization of the Na,K-ATPase reconstituted in DPPC/DPPE liposomes. Cell Biochemistry and Biophysics. 44: 438-45. PMID 16679531 DOI: 10.1385/CBB:44:3:438  0.01
2006 Ward RJ, McCrohan CR, White KN. Influence of aqueous aluminium on the immune system of the freshwater crayfish Pacifasticus leniusculus. Aquatic Toxicology (Amsterdam, Netherlands). 77: 222-8. PMID 16436302 DOI: 10.1016/j.aquatox.2005.12.006  0.01
2006 Novotny J, Durchankova D, Ward RJ, Carrillo JJ, Svoboda P, Milligan G. Functional interactions between the alpha1b-adrenoceptor and Galpha11 are compromised by de-palmitoylation of the G protein but not of the receptor. Cellular Signalling. 18: 1244-51. PMID 16297597 DOI: 10.1016/J.Cellsig.2005.10.004  0.01
2006 Ruller R, Rosa JC, Faça VM, Greene LJ, Ward RJ. Efficient constitutive expression of Bacillus subtilis xylanase A in Escherichia coli DH5alpha under the control of the Bacillus BsXA promoter. Biotechnology and Applied Biochemistry. 43: 9-15. PMID 15982188 DOI: 10.1042/BA20050016  0.01
2005 Murakami MT, Ruller R, Ward RJ, Arni RK. Crystallization and preliminary X-ray crystallographic studies of the mesophilic xylanase A from Bacillus subtilis 1A1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 219-20. PMID 16510999 DOI: 10.1107/S1744309105000904  0.01
2005 Murakami MT, Arni RK, Vieira DS, Degrève L, Ruller R, Ward RJ. Correlation of temperature induced conformation change with optimum catalytic activity in the recombinant G/11 xylanase A from Bacillus subtilis strain 168 (1A1). Febs Letters. 579: 6505-10. PMID 16289057 DOI: 10.1016/j.febslet.2005.10.039  0.01
2005 Ward RJ, Milligan G. A key serine for the GTPase-activating protein function of regulator of G protein signaling proteins is not a general target for 14-3-3 interactions. Molecular Pharmacology. 68: 1821-30. PMID 16160139 DOI: 10.1124/MOL.105.015073  0.01
2005 Kenigfest N, Belekhova M, Repérant J, Rio JP, Ward R, Vesselkin N. The turtle thalamic anterior entopeduncular nucleus shares connectional and neurochemical characteristics with the mammalian thalamic reticular nucleus Journal of Chemical Neuroanatomy. 30: 129-143. PMID 16140498 DOI: 10.1016/j.jchemneu.2005.07.001  0.01
2005 Médina M, Repérant J, Miceli D, Ward R, Arckens L. GnRH-immunoreactive centrifugal visual fibers in the Nile crocodile (Crocodylus niloticus). Brain Research. 1052: 112-7. PMID 16002052 DOI: 10.1016/j.brainres.2005.06.012  0.01
2005 Hauk P, Negrotto S, Romero EC, Vasconcellos SA, Genovez ME, Ward RJ, Schattner M, Goméz RM, Ho PL. Expression and characterization of HlyX hemolysin from Leptospira interrogans serovar Copenhageni: potentiation of hemolytic activity by LipL32. Biochemical and Biophysical Research Communications. 333: 1341-7. PMID 15990088 DOI: 10.1016/j.bbrc.2005.06.045  0.01
2005 Ruller R, Aragão EA, Chioato L, Ferreira TL, de Oliveira AH, Sà JM, Ward RJ. A predominant role for hydrogen bonding in the stability of the homodimer of bothropstoxin-I, A lysine 49-phospholipase A2. Biochimie. 87: 993-1003. PMID 15967564 DOI: 10.1016/j.biochi.2005.04.008  0.01
2005 Watanabe L, Soares AM, Ward RJ, Fontes MR, Arni RK. Structural insights for fatty acid binding in a Lys49-phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid. Biochimie. 87: 161-7. PMID 15760708 DOI: 10.1016/J.BIOCHI.2004.11.005  0.01
2005 Ambrosio AL, Nonato MC, de Araújo HS, Arni R, Ward RJ, Ownby CL, de Souza DH, Garratt RC. A molecular mechanism for Lys49-phospholipase A2 activity based on ligand-induced conformational change. The Journal of Biological Chemistry. 280: 7326-35. PMID 15596433 DOI: 10.1074/Jbc.M410588200  0.01
2005 Cecchini AL, Soares AM, Cecchini R, de Oliveira AH, Ward RJ, Giglio JR, Arantes EC. Effect of crotapotin on the biological activity of Asp49 and Lys49 phospholipases A(2) from Bothrops snake venoms. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 138: 429-36. PMID 15536050 DOI: 10.1016/J.CCA.2004.07.010  0.01
2005 Herzig V, Ward RJ, Dos Santos WF. Ontogenetic changes in Phoneutria nigriventer (Araneae, Ctenidae) spider venom. Toxicon : Official Journal of the International Society On Toxinology. 44: 635-40. PMID 15501289 DOI: 10.1016/J.TOXICON.2004.07.020  0.01
2005 Médina M, Repérant J, Ward R, Miceli D. Presumptive FMRF-amide-like immunoreactive retinopetal fibres in Crocodylus niloticus. Brain Research. 1025: 231-6. PMID 15464765 DOI: 10.1016/j.brainres.2004.08.008  0.01
2004 Bortoleto-Bugs RK, Neto AA, Ward RJ. Activation of Ca2+-independent membrane-damaging activity in Lys49-phospholipase A2 promoted by amphiphilic molecules. Biochemical and Biophysical Research Communications. 322: 364-72. PMID 15325239 DOI: 10.1016/J.BBRC.2004.06.181  0.01
2004 Milligan G, Feng GJ, Ward RJ, Sartania N, Ramsay D, McLean AJ, Carillo JJ. G protein-coupled receptor fusion proteins in drug discovery Current Pharmaceutical Design. 10: 1989-2001. PMID 15279540 DOI: 10.2174/1381612043384295  0.01
2004 Heydorn A, Ward RJ, Jorgensen R, Rosenkilde MM, Frimurer TM, Milligan G, Kostenis E. Identification of a novel site within G protein alpha subunits important for specificity of receptor-G protein interaction. Molecular Pharmacology. 66: 250-9. PMID 15266015 DOI: 10.1124/MOL.66.2.250  0.01
2004 Ward RJ, Milligan G. Analysis of function of receptor-G-protein and receptor-RGS fusion proteins. Methods in Molecular Biology (Clifton, N.J.). 259: 225-47. PMID 15250496 DOI: 10.1385/1-59259-754-8:225  0.01
2004 Kenigfest N, Rio JP, Belekhova M, Repérant J, Vesselkin N, Ward R. Pretectal and tectal afferents to the dorsal lateral geniculate nucleus of the turtle: An electron microscopic axon tracing and γ-aminobutyric acid immunocytochemical study Journal of Comparative Neurology. 475: 107-127. PMID 15176088 DOI: 10.1002/cne.20159  0.01
2004 Sá JM, Chioato L, Ferreira TL, De Oliveira AH, Ruller R, Rosa JC, Greene LJ, Ward RJ. Topology of the substrate-binding site of a Lys49-phospholipase A2 influences Ca2+-independent membrane-damaging activity. The Biochemical Journal. 382: 191-8. PMID 15147240 DOI: 10.1042/BJ20031946  0.01
2004 Rodrigues MC, Guizzo R, Gobbo-Neto L, Ward RJ, Lopes NP, dos Santos WF. The biological activity in mammals and insects of the nucleosidic fraction from the spider Parawixia bistriata. Toxicon : Official Journal of the International Society On Toxinology. 43: 375-83. PMID 15051400 DOI: 10.1016/J.TOXICON.2004.01.009  0.01
2004 Chioato L, Ward RJ. Mapping structural determinants of biological activities in snake venom phospholipases A2 by sequence analysis and site directed mutagenesis. Toxicon : Official Journal of the International Society On Toxinology. 42: 869-83. PMID 15019488 DOI: 10.1016/J.TOXICON.2003.11.027  0.01
2004 Flanagan JU, Maréchal JD, Ward R, Kemp CA, McLaughlin LA, Sutcliffe MJ, Roberts GC, Paine MJ, Wolf CR. Phe120 contributes to the regiospecificity of cytochrome P450 2D6: mutation leads to the formation of a novel dextromethorphan metabolite. The Biochemical Journal. 380: 353-60. PMID 14992686 DOI: 10.1042/BJ20040062  0.01
2004 Médina M, Repérant J, Ward R, Miceli D. Centrifugal visual system of Crocodylus niloticus: a hodological, histochemical, and immunocytochemical study. The Journal of Comparative Neurology. 468: 65-85. PMID 14648691 DOI: 10.1002/cne.10959  0.01
2003 Ward RJ, Wilmet S, Legssyer R, Crichton RR. Iron supplementation during pregnancy--a necessary or toxic supplement? Bioinorganic Chemistry and Applications. 169-76. PMID 18365051 DOI: 10.1155/S156536330300013X  0.01
2003 Bugs MR, Forato LA, Bortoleto-Bugs RK, Fischer H, Mascarenhas YP, Ward RJ, Colnago LA. Spectroscopic characterization and structural modeling of prolamin from maize and pearl millet. European Biophysics Journal : Ebj. 33: 335-43. PMID 14508615 DOI: 10.1007/s00249-003-0354-3  0.01
2003 Bahia DS, Sartania N, Ward RJ, Cavalli A, Jones TL, Druey KM, Milligan G. Concerted stimulation and deactivation of pertussis toxin-sensitive G proteins by chimeric G protein-coupled receptor-regulator of G protein signaling 4 fusion proteins: analysis of the contribution of palmitoylated cysteine residues to the GAP activity of RGS4. Journal of Neurochemistry. 85: 1289-98. PMID 12753087  0.01
2003 Bertaso F, Ward RJ, Viard P, Milligan G, Dolphin AC. Mechanism of action of Gq to inhibit G beta gamma modulation of CaV2.2 calcium channels: probed by the use of receptor-G alpha tandems. Molecular Pharmacology. 63: 832-43. PMID 12644584 DOI: 10.1124/MOL.63.4.832  0.01
2003 Osterhout JL, Waheed AA, Hiol A, Ward RJ, Davey PC, Nini L, Wang J, Milligan G, Jones TL, Druey KM. Palmitoylation regulates regulator of G-protein signaling (RGS) 16 function. II. Palmitoylation of a cysteine residue in the RGS box is critical for RGS16 GTPase accelerating activity and regulation of Gi-coupled signalling. The Journal of Biological Chemistry. 278: 19309-16. PMID 12642592 DOI: 10.1074/jbc.M210124200  0.01
2003 Soares AM, Marcussi S, Stábeli RG, França SC, Giglio JR, Ward RJ, Arantes EC. Structural and functional analysis of BmjMIP, a phospholipase A2 myotoxin inhibitor protein from Bothrops moojeni snake plasma. Biochemical and Biophysical Research Communications. 302: 193-200. PMID 12604331 DOI: 10.1016/S0006-291X(03)00155-4  0.01
2003 Ruller R, Ferreira TL, de Oliveira AH, Ward RJ. Chemical denaturation of a homodimeric lysine-49 phospholipase A2: a stable dimer interface and a native monomeric intermediate. Archives of Biochemistry and Biophysics. 411: 112-20. PMID 12590929 DOI: 10.1016/S0003-9861(02)00712-9  0.01
2003 Konozy EH, Bernardes ES, Rosa C, Faca V, Greene LJ, Ward RJ. Isolation, purification, and physicochemical characterization of a D-galactose-binding lectin from seeds of Erythrina speciosa. Archives of Biochemistry and Biophysics. 410: 222-9. PMID 12573281 DOI: 10.1016/S0003-9861(02)00695-1  0.01
2003 Belekhova M, Kenigfest N, Rio JP, Repérant J, Ward R, Vesselkin N, Karamian O. Tectothalamic visual projections in turtles: Their cells of origin revealed by tracing methods Journal of Comparative Neurology. 457: 37-56. PMID 12541323 DOI: 10.1002/cne.10487  0.01
2003 Rigos CF, Santos HdL, Thedei G, Ward RJ, Ciancaglini P. Influence of enzyme conformational changes on catalytic activity investigated by circular dichroism spectroscopy Biochemistry and Molecular Biology Education. 31: 329-332. DOI: 10.1002/bmb.2003.494031050264  0.01
2002 Konozy EH, Mulay R, Faca V, Ward RJ, Greene LJ, Roque-Barriera MC, Sabharwal S, Bhide SV. Purification, some properties of a D-galactose-binding leaf lectin from Erythrina indica and further characterization of seed lectin. Biochimie. 84: 1035-43. PMID 12504284 DOI: 10.1016/S0300-9084(02)00003-2  0.01
2002 Chioato L, De Oliveira AH, Ruller R, Sá JM, Ward RJ. Distinct sites for myotoxic and membrane-damaging activities in the C-terminal region of a Lys49-phospholipase A2. The Biochemical Journal. 366: 971-6. PMID 12079495 DOI: 10.1042/BJ20020092  0.01
2002 Pierre-Simons J, Repérant J, Mahouche M, Ward R. Development of tyrosine hydroxylase-immunoreactive systems in the brain of the larval lamprey Lampetra fluviatilis. The Journal of Comparative Neurology. 447: 163-76. PMID 11977119 DOI: 10.1002/cne.10225  0.01
2002 Mermet N, Angulo J, Médina M, Repérant J, Ward R, Araneda S. Expression of Kin, a nuclear protein binding to curved DNA, in the brain of the frog (Rana esculenta), turtle (Trachemys scripta), quail (Coturnix coturnix) and mouse (Mus musculus). Anatomy and Embryology. 205: 37-51. PMID 11875664 DOI: 10.1007/s00429-001-0224-7  0.01
2002 Ward RJ, Chioato L, de Oliveira AH, Ruller R, Sá JM. Active-site mutagenesis of a Lys49-phospholipase A2: biological and membrane-disrupting activities in the absence of catalysis. The Biochemical Journal. 362: 89-96. PMID 11829743 DOI: 10.1042/0264-6021:3620089  0.01
2002 Ward RJ, Milligan G. Reciprocal mutations of highly conserved residues in transmembrane helices 2 and 7 of the alpha(2A)-adrenoceptor restore agonist activation of G(i1)alpha. Cellular Signalling. 14: 139-44. PMID 11781138 DOI: 10.1016/S0898-6568(01)00218-2  0.01
2002 WARD RJ, CHIOATO L, de OLIVEIRA AHC, RULLER R, SÁ JM. Active-site mutagenesis of a Lys49-phospholipase A2: biological and membrane-disrupting activities in the absence of catalysis Biochemical Journal. 362: 89-96. DOI: 10.1042/bj3620089  0.01
2001 Hoffmann M, Ward RJ, Cavalli A, Carr IC, Milligan G. Differential capacities of the RGS1, RGS16 and RGS-GAIP regulators of G protein signaling to enhance alpha2A-adrenoreceptor agonist-stimulated GTPase activity of G(o1)alpha. Journal of Neurochemistry. 78: 797-806. PMID 11520900 DOI: 10.1046/j.1471-4159.2001.00479.x  0.01
2001 de Oliveira AH, Giglio JR, Andrião-Escarso SH, Ward RJ. The effect of resonance energy homotransfer on the intrinsic tryptophan fluorescence emission of the bothropstoxin-I dimer. Biochemical and Biophysical Research Communications. 284: 1011-5. PMID 11409896 DOI: 10.1006/BBRC.2001.5073  0.01
2001 de Oliveira AH, Giglio JR, Andrião-Escarso SH, Ito AS, Ward RJ. A pH-induced dissociation of the dimeric form of a lysine 49-phospholipase A2 abolishes Ca2+-independent membrane damaging activity. Biochemistry. 40: 6912-20. PMID 11389606 DOI: 10.1021/BI0026728  0.01
2001 Soares AM, Andrião-Escarso SH, Bortoleto RK, Rodrigues-Simioni L, Arni RK, Ward RJ, Gutiérrez JM, Giglio JR. Dissociation of enzymatic and pharmacological properties of piratoxins-I and -III, two myotoxic phospholipases A2 from Bothrops pirajai snake venom. Archives of Biochemistry and Biophysics. 387: 188-96. PMID 11370840 DOI: 10.1006/ABBI.2000.2244  0.01
2001 Ward RJ, de Oliveira AH, Bortoleto RK, Rosa JC, Faça VM, Greene LJ. Refolding and purification of Bothropstoxin-I, a Lys49-phospholipase A2 homologue, expressed as inclusion bodies in Escherichia coli. Protein Expression and Purification. 21: 134-40. PMID 11162398 DOI: 10.1006/PREP.2000.1353  0.01
2000 Ward RJ, Milligan G. An Asp79Asn mutation of the alpha2A-adrenoceptor interferes equally with agonist activation of individual Gialpha-family G protein subtypes. Febs Letters. 462: 459-63. PMID 10622745 DOI: 10.1016/S0014-5793(99)01581-1  0.01
2000 Ward RJ, de Oliveira AHC, Chioato L, Bortoleto RK, Rosa JC, Faça VM, Green LJ. MUTAGENEIS OF THE ACTIVE SITE REGION OF BOTHROPSTOXIN-I, A Lys49-PHOSPHOLIPASE A2 HOMOLOGUE Biochemical Society Transactions. 28: A395-A395. DOI: 10.1042/BST028A395C  0.01
1999 Homsi-Brandeburgo MI, Toyama MH, Marangoni S, Ward RJ, Giglio JR, Hartley BS. The amino acid sequence of ribitol dehydrogenase-F, a mutant enzyme with improved xylitol dehydrogenase activity. Journal of Protein Chemistry. 18: 489-95. PMID 10449046 DOI: 10.1023/A:1020601011846  0.01
1999 Arni RK, Fontes MR, Barberato C, Gutiérrez JM, Díaz C, Ward RJ. Crystal structure of myotoxin II, a monomeric Lys49-phospholipase A2 homologue isolated from the venom of Cerrophidion (Bothrops) godmani. Archives of Biochemistry and Biophysics. 366: 177-82. PMID 10356281 DOI: 10.1006/ABBI.1999.1210  0.01
1999 de Azevedo WF, Ward RJ, Gutiérrez JM, Arni RK. Structure of a Lys49-phospholipase A2 homologue isolated from the venom of Bothrops nummifer (jumping viper). Toxicon : Official Journal of the International Society On Toxinology. 37: 371-84. PMID 10078866 DOI: 10.1016/S0041-0101(98)00189-5  0.01
1999 Arni RK, Watanabe L, Ward RJ, Kreitman RJ, Kumar K, Walz FG. Three-dimensional structure of ribonuclease T1 complexed with an isosteric phosphonate substrate analogue of GpU: alternate substrate binding modes and catalysis. Biochemistry. 38: 2452-61. PMID 10029539 DOI: 10.1021/Bi982612Q  0.01
1999 Ward RJ, de Azevedo WF, Arni RK. At the interface: crystal structures of phospholipases A2. Toxicon : Official Journal of the International Society On Toxinology. 36: 1623-33. PMID 9792179 DOI: 10.1016/S0041-0101(98)00155-X  0.01
1999 Ward R, Milligan G. Construction and Analysis of α2A-Adrenoceptor Gi/Goα-Subunit Fusion Proteins Biochemical Society Transactions. 27: A115-A115. DOI: 10.1042/BST027A115  0.01
1999 Milligan G, Groake DA, MacLean A, Ward R, Fong CW, Cavalli A, Drmota T. Diversity in the signaling and regulation of G protein-coupled receptors Biochemical Society Transactions. 27: A24-A24. DOI: 10.1042/BST027A024C  0.01
1998 de Azevedo WF, Ward RJ, Canduri F, Soares A, Giglio JR, Arni RK. Crystal structure of piratoxin-I: a calcium-independent, myotoxic phospholipase A2-homologue from Bothrops pirajai venom. Toxicon : Official Journal of the International Society On Toxinology. 36: 1395-406. PMID 9723838 DOI: 10.1016/S0041-0101(98)00017-8  0.01
1998 Canduri F, Ward RJ, de Azevedo Júnior WF, Gomes RA, Arni RK. Purification and partial characterization of cathepsin D from porcine (Sus scrofa) liver using affinity chromatography. Biochemistry and Molecular Biology International. 45: 797-803. PMID 9713704 DOI: 10.1080/15216549800203222  0.01
1998 Ward RJ, Alves AR, Ruggiero Neto J, Arni RK, Casari G. A SequenceSpace analysis of Lys49 phopholipases A2: clues towards identification of residues involved in a novel mechanism of membrane damage and in myotoxicity. Protein Engineering. 11: 285-94. PMID 9680190 DOI: 10.1093/PROTEIN/11.4.285  0.01
1998 de Sousa MV, Morhy L, Arni RK, Ward RJ, Díaz C, Gutiérrez JM. Amino acid sequence of a myotoxic Lys49-phospholipase A2 homologue from the venom of Cerrophidion (Bothrops) godmani. Biochimica Et Biophysica Acta. 1384: 204-8. PMID 9659381 DOI: 10.1016/S0167-4838(98)00023-5  0.01
1998 Canduri F, Mancuso LC, Soares AM, Giglio JR, Ward RJ, Arni RK. Crystallization of piratoxin I, a myotoxic Lys49-phospholipase A2 homologue isolated from the venom of Bothrops pirajai. Toxicon : Official Journal of the International Society On Toxinology. 36: 547-51. PMID 9637374 DOI: 10.1016/S0041-0101(97)00120-7  0.01
1998 Da Silva Giotto MT, Garratt RC, Oliva G, Mascarenhas YP, Giglio JR, Cintra ACO, De Azevedo WF, Arni RK, Ward RJ. Crystallographic and spectroscopic characterization of a molecular hinge: Conformational changes in Bothropstoxin I, a dimeric Lys49- phospholipase A2 homologue Proteins: Structure, Function and Genetics. 30: 442-454. PMID 9533628 DOI: 10.1002/(Sici)1097-0134(19980301)30:4<442::Aid-Prot11>3.0.Co;2-I  0.01
1998 Bortoleto RK, de Oliveira AH, Ruller R, Arni RK, Ward RJ. Tertiary structural changes of the alpha-hemolysin from Staphylococcus aureus on association with liposome membranes. Archives of Biochemistry and Biophysics. 351: 47-52. PMID 9500849 DOI: 10.1006/ABBI.1997.0550  0.01
1997 Arni RK, Ward RJ. Phospholipase A2--a structural review. Toxicon : Official Journal of the International Society On Toxinology. 34: 827-41. PMID 8875770 DOI: 10.1016/0041-0101(96)00036-0  0.01
1997 Ward R. STRUCTURE/FUNCTION RELATIONSHIPS OF K49-PHOSPHOLIPASE A2 (PLA2) HOMOLOGUES - FLUORESCENCE SPECTROSCOPY STUDIES USING BOTHROPSTOXIN I FROM Bothrops jararacussu AS A MODEL SYSTEM Journal of Venomous Animals and Toxins. 3: 356-356. DOI: 10.1590/S0104-79301997000200019  0.01
1996 Bortoleto RK, Ward RJ, Giglio JR, Cintra AC, Arni RK. Crystallization of bothropstoxin II isolated from the venom of Bothrops jararacussu. Toxicon : Official Journal of the International Society On Toxinology. 34: 614-7. PMID 8783457 DOI: 10.1016/0041-0101(95)00143-3  0.01
1995 Arni RK, Ward RJ, Gutierrez JM, Tulinsky A. Structure of a calcium-independent phospholipase-like myotoxic protein from Bothrops asper venom. Acta Crystallographica. Section D, Biological Crystallography. 51: 311-7. PMID 15299297 DOI: 10.1107/S0907444994011455  0.01
1995 Ward RJ, Monesi N, Arni RK, Larson RE, Paço-Larson ML. Sequence of a cDNA encoding bothropstoxin I, a myotoxin from the venom of Bothrops jararacussu. Gene. 156: 305-6. PMID 7758974 DOI: 10.1016/0378-1119(95)00099-R  0.01
1995 Hufton SE, Ward RJ, Bunce NA, Armstrong JT, Fletcher AJ, Glass RE. Structure-function analysis of the vitamin B12 receptor of Escherichia coli by means of informational suppression. Molecular Microbiology. 15: 381-93. PMID 7746157 DOI: 10.1111/j.1365-2958.1995.tb02251.x  0.01
1995 Arni RK, Ward RJ, Cintra AC, Giglio JR. Crystallization and preliminary diffraction data of bothropstoxin I isolated from the venom of Bothrops jararacussu. Toxicon : Official Journal of the International Society On Toxinology. 33: 383-6. PMID 7638878 DOI: 10.1016/0041-0101(94)00156-3  0.01
1995 Ward RJ, Glass RE. The 3'-terminal half of the btuB gene of Citrobacter freundii defines essential residues and supports a topological model for the outer membrane receptor. Molecular Microbiology. 16: 813-5. PMID 7476175 DOI: 10.1111/j.1365-2958.1995.tb02442.x  0.01
1993 Arni RK, Ward R, Gutierrez JM. Crystal structures of LYS49 phospholipases A2 fromBothrops asperandBothrops godmanivenoms Acta Crystallographica Section a Foundations of Crystallography. 49: c105-c105. DOI: 10.1107/S0108767378097007  0.01
1992 Ward RJ. Save the porphyries Resources Policy. 18: 304-305. DOI: 10.1016/0301-4207(92)90018-5  0.01
1990 Hunt PD, Tolley SP, Ward RJ, Hill CP, Dodson GG. Expression, purification and crystallization of penicillin G acylase from Escherichia coli ATCC 11105. Protein Engineering. 3: 635-9. PMID 2217137 DOI: 10.1093/PROTEIN/3.7.635  0.01
1975 Ames DE, Ward RJ. [1,4 ]Benzodioxinopyridazines Journal of the Chemical Society, Perkin Transactions 1. 534-538. DOI: 10.1039/P19750000534  0.01
1975 AMES DE, WARD RJ. ChemInform Abstract: (1,4)BENZODIOXINOPYRIDAZINES Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/chin.197524296  0.01
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