| Year |
Citation |
Score |
| 2019 |
Eroglu B, Pang J, Jin X, Xi C, Moskophidis D, Mivechi NF. HSF1-mediated Control of Cellular Energy Metabolism and mTORC1 Activation Drive Acute T Cell Lymphoblastic Leukemia Progression. Molecular Cancer Research : McR. PMID 31744878 DOI: 10.1158/1541-7786.Mcr-19-0217 |
0.447 |
|
| 2019 |
Cho W, Jin X, Pang J, Wang Y, Mivechi NF, Moskophidis D. The Molecular Chaperone HSP70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA-Damage and MAPK/ERK Signaling Pathways. Molecular and Cellular Biology. PMID 30745413 DOI: 10.1128/Mcb.00391-18 |
0.32 |
|
| 2018 |
Jin X, Qiao A, Moskophidis D, Mivechi NF. Modulation of HSF1 Activity Through Silencing of Ser303/Ser307 Phosphorylation Supports A Metabolic Program Leading to Age-related Obesity and Insulin Resistance. Molecular and Cellular Biology. PMID 29941492 DOI: 10.1128/Mcb.00095-18 |
0.303 |
|
| 2017 |
Jin X, Qiao A, Moskophidis D, Mivechi NF. Abrogation of heat shock factor 1 (Hsf1) phosphorylation deregulates its activity and lowers activation threshold, leading to obesity in mice. The Journal of Biological Chemistry. PMID 28724629 DOI: 10.1074/Jbc.M117.789354 |
0.309 |
|
| 2017 |
Qiao A, Jin X, Pang J, Moskophidis D, Mivechi NF. The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis. The Journal of Cell Biology. PMID 28183717 DOI: 10.1083/Jcb.201607091 |
0.321 |
|
| 2009 |
Jin X, Moskophidis D, Hu Y, Phillips A, Mivechi NF. Heat shock factor 1 deficiency via its downstream target gene alphaB-crystallin (Hspb5) impairs p53 degradation. Journal of Cellular Biochemistry. 107: 504-15. PMID 19343786 DOI: 10.1002/Jcb.22151 |
0.315 |
|
| 2008 |
Chen M, Lan S, Ou R, Price GE, Jiang H, de la Torre JC, Moskophidis D. Genomic and biological characterization of aggressive and docile strains of lymphocytic choriomeningitis virus rescued from a plasmid-based reverse-genetics system. The Journal of General Virology. 89: 1421-33. PMID 18474558 DOI: 10.1099/Vir.0.83464-0 |
0.726 |
|
| 2008 |
Ou R, Zhang M, Huang L, Flavell RA, Koni PA, Moskophidis D. Regulation of immune response and inflammatory reactions against viral infection by VCAM-1. Journal of Virology. 82: 2952-65. PMID 18216105 DOI: 10.1128/Jvi.02191-07 |
0.777 |
|
| 2008 |
Ou R, Zhang M, Huang L, Moskophidis D. Control of virus-specific CD8+ T-cell exhaustion and immune-mediated pathology by E3 ubiquitin ligase Cbl-b during chronic viral infection. Journal of Virology. 82: 3353-68. PMID 18199651 DOI: 10.1128/Jvi.01350-07 |
0.785 |
|
| 2007 |
Huang L, Min JN, Masters S, Mivechi NF, Moskophidis D. Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption. Genesis (New York, N.Y. : 2000). 45: 487-501. PMID 17661394 DOI: 10.1002/Dvg.20319 |
0.329 |
|
| 2005 |
Price GE, Huang L, Ou R, Zhang M, Moskophidis D. Perforin and Fas cytolytic pathways coordinately shape the selection and diversity of CD8+-T-cell escape variants of influenza virus. Journal of Virology. 79: 8545-59. PMID 15956596 DOI: 10.1128/Jvi.79.13.8545-8559.2005 |
0.77 |
|
| 2004 |
Min JN, Zhang Y, Moskophidis D, Mivechi NF. Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation. Genesis (New York, N.Y. : 2000). 40: 205-17. PMID 15593327 DOI: 10.1002/Gene.20087 |
0.304 |
|
| 2004 |
Gronski MA, Boulter JM, Moskophidis D, Nguyen LT, Holmberg K, Elford AR, Deenick EK, Kim HO, Penninger JM, Odermatt B, Gallimore A, Gascoigne NR, Ohashi PS. TCR affinity and negative regulation limit autoimmunity. Nature Medicine. 10: 1234-9. PMID 15467726 DOI: 10.1038/Nm1114 |
0.468 |
|
| 2004 |
Zhou S, Ou R, Huang L, Price GE, Moskophidis D. Differential tissue-specific regulation of antiviral CD8+ T-cell immune responses during chronic viral infection. Journal of Virology. 78: 3578-600. PMID 15016881 DOI: 10.1128/Jvi.78.7.3578-3600.2004 |
0.772 |
|
| 2004 |
Wang G, Ying Z, Jin X, Tu N, Zhang Y, Phillips M, Moskophidis D, Mivechi NF. Essential requirement for both hsf1 and hsf2 transcriptional activity in spermatogenesis and male fertility. Genesis (New York, N.Y. : 2000). 38: 66-80. PMID 14994269 DOI: 10.1002/Gene.20005 |
0.338 |
|
| 2003 |
Wang G, Zhang J, Moskophidis D, Mivechi NF. Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis. Genesis (New York, N.Y. : 2000). 36: 48-61. PMID 12748967 DOI: 10.1002/Gene.10200 |
0.313 |
|
| 2002 |
Zhang Y, Huang L, Zhang J, Moskophidis D, Mivechi NF. Targeted disruption of hsf1 leads to lack of thermotolerance and defines tissue-specific regulation for stress-inducible Hsp molecular chaperones. Journal of Cellular Biochemistry. 86: 376-93. PMID 12112007 DOI: 10.1002/Jcb.10232 |
0.34 |
|
| 2002 |
Zhou S, Ou R, Huang L, Moskophidis D. Critical role for perforin-, Fas/FasL-, and TNFR1-mediated cytotoxic pathways in down-regulation of antigen-specific T cells during persistent viral infection. Journal of Virology. 76: 829-40. PMID 11752172 DOI: 10.1128/Jvi.76.2.829-840.2002 |
0.785 |
|
| 2001 |
Huang L, Mivechi NF, Moskophidis D. Insights into regulation and function of the major stress-induced hsp70 molecular chaperone in vivo: analysis of mice with targeted gene disruption of the hsp70.1 or hsp70.3 gene. Molecular and Cellular Biology. 21: 8575-91. PMID 11713291 DOI: 10.1128/Mcb.21.24.8575-8591.2001 |
0.302 |
|
| 2001 |
Ou R, Zhou S, Huang L, Moskophidis D. Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells. Journal of Virology. 75: 8407-23. PMID 11507186 DOI: 10.1128/Jvi.75.18.8407-8423.2001 |
0.786 |
|
| 2000 |
Price GE, Ou R, Jiang H, Huang L, Moskophidis D. Viral escape by selection of cytotoxic T cell-resistant variants in influenza A virus pneumonia. The Journal of Experimental Medicine. 191: 1853-67. PMID 10839802 DOI: 10.1084/Jem.191.11.1853 |
0.773 |
|
| 2000 |
Price GE, Gaszewska-Mastarlarz A, Moskophidis D. The Role of Alpha/Beta and Gamma Interferons in Development of Immunity to Influenza A Virus in Mice Journal of Virology. 74: 3996-4003. PMID 10756011 DOI: 10.1128/Jvi.74.9.3996-4003.2000 |
0.592 |
|
| 1998 |
Moskophidis D, Kioussis D. Contribution of virus-specific CD8+ cytotoxic T cells to virus clearance or pathologic manifestations of influenza virus infection in a T cell receptor transgenic mouse model. The Journal of Experimental Medicine. 188: 223-32. PMID 9670035 DOI: 10.1084/Jem.188.2.223 |
0.623 |
|
| 1995 |
Moskophidis D, Zinkernagel RM. Immunobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virus. Journal of Virology. 69: 2187-93. PMID 7533851 DOI: 10.1128/Jvi.69.4.2187-2193.1995 |
0.602 |
|
| 1995 |
Moskophidis D, Battegay M, van den Broek M, Laine E, Hoffmann-Rohrer U, Zinkernagel RM. Role of virus and host variables in virus persistence or immunopathological disease caused by a non-cytolytic virus. The Journal of General Virology. 76: 381-91. PMID 7531218 DOI: 10.1099/0022-1317-76-2-381 |
0.582 |
|
| 1994 |
Moskophidis D, Battegay M, Bruendler MA, Laine E, Gresser I, Zinkernagel RM. Resistance of lymphocytic choriomeningitis virus to alpha/beta interferon and to gamma interferon. Journal of Virology. 68: 1951-5. PMID 8107255 DOI: 10.1128/Jvi.68.3.1951-1955.1994 |
0.341 |
|
| 1993 |
Moskophidis D, Lechner F, Pircher H, Zinkernagel RM. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature. 362: 758-61. PMID 8469287 DOI: 10.1038/362758A0 |
0.664 |
|
| 1993 |
Moskophidis D, Laine E, Zinkernagel RM. Peripheral clonal deletion of antiviral memory CD8+ T cells. European Journal of Immunology. 23: 3306-11. PMID 8258345 DOI: 10.1002/Eji.1830231237 |
0.568 |
|
| 1993 |
Zinkernagel RM, Moskophidis D, Kündig T, Oehen S, Pircher H, Hengartner H. Effector T-cell induction and T-cell memory versus peripheral deletion of T cells. Immunological Reviews. 133: 199-223. PMID 8225368 DOI: 10.1111/J.1600-065X.1993.Tb01517.X |
0.424 |
|
| 1992 |
Althage A, Odermatt B, Moskophidis D, Kündig T, Hoffman-Rohrer U, Hengartner H, Zinkernagel RM. Immunosuppression by lymphocytic choriomeningitis virus infection: competent effector T and B cells but impaired antigen presentation. European Journal of Immunology. 22: 1803-12. PMID 1623925 DOI: 10.1002/Eji.1830220720 |
0.643 |
|
| 1992 |
Moskophidis D, Pircher H, Ciernik I, Odermatt B, Hengartner H, Zinkernagel RM. Suppression of virus-specific antibody production by CD8+ class I-restricted antiviral cytotoxic T cells in vivo. Journal of Virology. 66: 3661-8. PMID 1583725 DOI: 10.1128/Jvi.66.6.3661-3668.1992 |
0.631 |
|
| 1991 |
Moskophidis D, Frei K, Löhler J, Fontana A, Zinkernagel RM. Production of random classes of immunoglobulins in brain tissue during persistent viral infection paralleled by secretion of interleukin-6 (IL-6) but not IL-4, IL-5, and gamma interferon. Journal of Virology. 65: 1364-9. PMID 1899893 DOI: 10.1128/Jvi.65.3.1364-1369.1991 |
0.377 |
|
| 1991 |
Aebischer T, Moskophidis D, Rohrer UH, Zinkernagel RM, Hengartner H. In vitro selection of lymphocytic choriomeningitis virus escape mutants by cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 88: 11047-51. PMID 1722316 DOI: 10.1073/Pnas.88.24.11047 |
0.571 |
|
| 1991 |
Pircher H, Rohrer UH, Moskophidis D, Zinkernagel RM, Hengartner H. Lower receptor avidity required for thymic clonal deletion than for effector T-cell function. Nature. 351: 482-5. PMID 1710780 DOI: 10.1038/351482A0 |
0.545 |
|
| 1990 |
Pircher H, Moskophidis D, Rohrer U, Bürki K, Hengartner H, Zinkernagel RM. Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo. Nature. 346: 629-33. PMID 1696684 DOI: 10.1038/346629A0 |
0.599 |
|
| 1989 |
Moskophidis D, Fang L, Gossmann J, Lehmann-Grube F. Mechanism of recovery from acute virus infection. IX. Clearance of lymphocytic choriomeningitis (LCM) virus from the feet of mice undergoing LCM virus-specific delayed-type hypersensitivity reaction Journal of General Virology. 70: 3305-3316. PMID 2575136 DOI: 10.1099/0022-1317-70-12-3305 |
0.556 |
|
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