Year |
Citation |
Score |
2021 |
Cai W, Ratnayake R, Wang M, Chen QY, Raisch KP, Dang LH, Law BK, Luesch H. Inhibition of cotranslational translocation by apratoxin S4: Effects on oncogenic receptor tyrosine kinases and the fate of transmembrane proteins produced in the cytoplasm. Current Research in Pharmacology and Drug Discovery. 2: 100053. PMID 34909679 DOI: 10.1016/j.crphar.2021.100053 |
0.735 |
|
2018 |
Cai W, Ratnayake R, Gerber MH, Chen QY, Yu Y, Derendorf H, Trevino JG, Luesch H. Development of apratoxin S10 (Apra S10) as an anti-pancreatic cancer agent and its preliminary evaluation in an orthotopic patient-derived xenograft (PDX) model. Investigational New Drugs. PMID 30073464 DOI: 10.1007/S10637-018-0647-0 |
0.736 |
|
2018 |
Cai W, Matthew S, Chen QY, Paul VJ, Luesch H. Discovery of new A- and B-type laxaphycins with synergistic anticancer activity. Bioorganic & Medicinal Chemistry. PMID 29606488 DOI: 10.1016/J.Bmc.2018.03.022 |
0.731 |
|
2017 |
Cai W, Chen QY, Dang LH, Luesch H. Correction to "Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors". Acs Medicinal Chemistry Letters. 8: 1342. PMID 29266134 DOI: 10.1021/Acsmedchemlett.7B00498 |
0.749 |
|
2017 |
Cai W, Salvador-Reyes LA, Zhang W, Chen QY, Matthew S, Ratnayake R, Seo SJ, Dolles S, Gibson DJ, Paul VJ, Luesch H. Apratyramide, a Marine-Derived Peptidic Stimulator of VEGF-A and Other Growth Factors with Potential Application in Wound Healing. Acs Chemical Biology. PMID 29205032 DOI: 10.1021/Acschembio.7B00827 |
0.7 |
|
2017 |
Cai W, Chen QY, Dang LH, Luesch H. Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors. Acs Medicinal Chemistry Letters. 8: 1007-1012. PMID 29057042 DOI: 10.1021/Acsmedchemlett.7B00192 |
0.762 |
|
2016 |
Wu P, Cai W, Chen QY, Xu S, Yin R, Li Y, Zhang W, Luesch H. Total Synthesis and Biological Evaluation of Apratoxin E and Its C30 Epimer: Configurational Reassignment of the Natural Product. Organic Letters. PMID 27723359 DOI: 10.1021/Acs.Orglett.6B02780 |
0.695 |
|
2016 |
Cai W, Matthews JH, Paul VJ, Luesch H. Pitiamides A and B, Multifunctional Fatty Acid Amides from Marine Cyanobacteria. Planta Medica. PMID 27135625 DOI: 10.1055/S-0042-105157 |
0.7 |
|
2015 |
Cai W, Salvador-Reyes L, Zhang W, Matthew S, Ratnayake R, Paul V, Dang L, Luesch H. Discovery, synthesis, and biological evaluation of apratyramide, a marine-derived transcriptional stimulator of VEGF-A Planta Medica. 81. DOI: 10.1055/S-0035-1556169 |
0.724 |
|
2014 |
Chen QY, Liu Y, Cai W, Luesch H. Improved total synthesis and biological evaluation of potent apratoxin S4 based anticancer agents with differential stability and further enhanced activity. Journal of Medicinal Chemistry. 57: 3011-29. PMID 24660812 DOI: 10.1021/Jm4019965 |
0.754 |
|
2014 |
Chen Q, Liu Y, Cai W, Luesch H. Improved total synthesis and biological evaluation of potent apratoxin S4 based anticancer agents with enhanced activity Planta Medica. 80. DOI: 10.1055/S-0034-1382377 |
0.551 |
|
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